2-Oxopyrimidine
| Title | Journal |
|---|---|
| Reduction and methylation of ziprasidone by glutathione, aldehyde oxidase, and thiol S-methyltransferase in humans: an in vitro study. | Xenobiotica; the fate of foreign compounds in biological systems 20121101 |
| The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabetes. | The Journal of pharmacology and experimental therapeutics 20120701 |
| Role of glutamate 64 in the activation of the prodrug 5-fluorocytosine by yeast cytosine deaminase. | Biochemistry 20120110 |
| The (α-4) photoconjugates of 5-methylcytosine, 1,5-dimethylcytosine, 1-methylthymine and thymidine. | Photochemistry and photobiology 20120101 |
| Effects of a novel DNA methyltransferase inhibitor Zebularine on human lens epithelial cells. | Molecular vision 20120101 |
| Triple helical recognition of pyrimidine inversions in polypurine tracts of RNA by nucleobase-modified PNA. | Chemical communications (Cambridge, England) 20111021 |
| Synthesis of some pyrazolines and pyrimidines derived from polymethoxy chalcones as anticancer and antimicrobial agents. | Archiv der Pharmazie 20110901 |
| A novel HDAC inhibitor with a hydroxy-pyrimidine scaffold. | Bioorganic & medicinal chemistry letters 20110715 |
| An oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndrome. | Journal of lipid research 20110601 |
| Toxicokinetic model describing bioconcentration and biotransformation of diazinon in Daphnia magna. | Environmental science & technology 20110601 |
| 2´-deoxy-5,6-dihydro-5-azacytidine - a less toxic alternative of 2´-deoxy-5-azacytidine: a comparative study of hypomethylating potential. | Epigenetics 20110601 |
| Identifying chelators for metalloprotein inhibitors using a fragment-based approach. | Journal of medicinal chemistry 20110127 |
| Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets? | International journal of biological sciences 20110101 |
| Current and emerging 'at-site' pain medications: a review. | Journal of pain research 20110101 |
| Cytosine methyltransferases as tumor markers. | Current genomics 20101201 |
| Inhibition of murine DNA methyltransferase Dnmt3a by DNA duplexes containing pyrimidine-2(1H)-one. | Biochemistry. Biokhimiia 20100901 |
| The role of the formamide/zirconia system in the synthesis of nucleobases and biogenic carboxylic acid derivatives. | Journal of molecular evolution 20100801 |
| 2-[2-(2-Anilino-4-oxo-3,4-dihydro-quinazolin-3-yl)phen-oxy]-3-phenyl-quinazolin-4(3H)-one methanol hemisolvate. | Acta crystallographica. Section E, Structure reports online 20100801 |
| Supersonic jet UV spectrum and nonradiative processes of the thymine analogue 5-methyl-2-hydroxypyrimidine. | Physical chemistry chemical physics : PCCP 20100521 |
| Two solid phases of pyrimidin-1-ium hydrogen chloranilate monohydrate determined at 225 and 120 K. | Acta crystallographica. Section C, Crystal structure communications 20100315 |
| Determination of derivatized urea in exhaled breath condensate by LC-MS. | Journal of chromatographic science 20100201 |
| Tyrosine analogues for probing proton-coupled electron transfer processes in peptides and proteins. | Journal of the American Chemical Society 20100120 |
| Genome-wide gene expression analysis in response to organophosphorus pesticide chlorpyrifos and diazinon in C. elegans. | PloS one 20100101 |
| Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine. | PloS one 20100101 |
| Mutational analysis of the CG recognizing DNA methyltransferase SssI: insight into enzyme-DNA interactions. | Biochimica et biophysica acta 20091101 |
| Structural and mutational analysis of TenA protein (HP1287) from the Helicobacter pylori thiamin salvage pathway - evidence of a different substrate specificity. | The FEBS journal 20091101 |
| DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site. | Biochemical pharmacology 20090915 |
| Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy. | Current genomics 20090801 |
| Methyl 4-(3-eth-oxy-4-hydroxy-phen-yl)-6-methyl-2-oxo-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate monohydrate. | Acta crystallographica. Section E, Structure reports online 20090801 |
| Asymmetric autocatalysis triggered by carbon isotope (13C/12C) chirality. | Science (New York, N.Y.) 20090424 |
| Time-resolved transcriptome analysis of Bacillus subtilis responding to valine, glutamate, and glutamine. | PloS one 20090101 |
| Design and Synthesis of Imidazopyrimidine Derivatives as Potent iNOS Dimerization Inhibitors. | The open medicinal chemistry journal 20090101 |
| Synthesis and degradation of nucleic acid components by formamide and iron sulfur minerals. | Journal of the American Chemical Society 20081119 |
| Antioxidant properties of argpyrimidine. | European journal of pharmacology 20080928 |
| Electrochemically and photochemically active Palladium(II) heterotopic metallacalix[3]arenes. | Chemical communications (Cambridge, England) 20080828 |
| 2-Oxo-1,2-dihydro-pyrimidin-3-ium di-μ-chlorido-bis-{dichloridobis[pyrimidin-2(1H)-one-κN]cuprate(II)} dihydrate. | Acta crystallographica. Section E, Structure reports online 20080701 |
| Penta-kis(2-oxo-2,3-dihydro-pyrimidin-1-ium) di-μ(3)-chlorido-tri-μ(2)-chlorido-hexa-chloridotricadmate(II). | Acta crystallographica. Section E, Structure reports online 20080701 |
| cis-Aqua-dichlorido[pyrimidin-2(1H)-one-κN]copper(II). | Acta crystallographica. Section E, Structure reports online 20080701 |
| Three-state conical intersections in cytosine and pyrimidinone bases. | The Journal of chemical physics 20080607 |
| Two-photon absorption enhancement induced by aggregation due to intermolecular hydrogen bonding in V-shaped 2-hydroxypyrimidine derivatives. | Chemical communications (Cambridge, England) 20080521 |
| The first metal complexes of 4,6-diamino-1-hydro-5-hydroxy-pyrimidine-2-thione: preparation, physical and spectroscopic studies, and preliminary antimicrobial properties. | Bioinorganic chemistry and applications 20080101 |
| Cytosine in context: a theoretical study of substituent effects on the excitation energies of 2-pyrimidinone derivatives. | The journal of physical chemistry. A 20070906 |
| Stabilization of a transition-state analogue at the active site of yeast cytosine deaminase: importance of proton transfers. | The journal of physical chemistry. B 20070614 |
| Radiationless decay mechanism of cytosine: an ab initio study with comparisons to the fluorescent analogue 5-methyl-2-pyrimidinone. | The journal of physical chemistry. A 20070412 |
| Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells. | Molecular cancer 20070101 |
| Formamide as the main building block in the origin of nucleic acids. | BMC evolutionary biology 20070101 |
| Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer. | British journal of cancer 20061218 |
| A mass balance and disposition study of the DNA methyltransferase inhibitor zebularine (NSC 309132) and three of its metabolites in mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061001 |
| Diazinon, chlorpyrifos and parathion are metabolised by multiple cytochromes P450 in human liver. | Toxicology 20060705 |
| Expression of the E. coli fpg protein in CHO cells lowers endogenous oxypurine clustered damage levels and decreases accumulation of endogenous Hprt mutations. | Environmental and molecular mutagenesis 20060601 |
| Synthesis and SAR of highly potent and selective dopamine D3-receptor antagonists: variations on the 1H-pyrimidin-2-one theme. | Bioorganic & medicinal chemistry letters 20060401 |
| H2, N2, CO, and CO2 sorption properties of a series of robust sodalite-type microporous coordination polymers. | Inorganic chemistry 20060320 |
| Microwave-assisted synthesis of antimicrobial dihydropyridines and tetrahydropyrimidin-2-ones: novel compounds against aspergillosis. | Bioorganic & medicinal chemistry 20060215 |
| Synthesis and SAR of highly potent and selective dopamine D(3)-receptor antagonists: 1H-pyrimidin-2-one derivatives. | Bioorganic & medicinal chemistry letters 20060201 |
| Interaction of thioamides, selenoamides, and amides with diiodine. | Bioinorganic chemistry and applications 20060101 |
| Synthesis of new 2-thiouracil-5-sulphonamide derivatives with antibacterial and antifungal activity. | Archives of pharmacal research 20051101 |
| Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin. | Drug metabolism and disposition: the biological fate of chemicals 20050901 |
| Heteroleptic pyrimidine-2-olate and 4,4[prime or minute]-bipyridine copper(II) layered metal-organic frameworks with swelling properties. | Dalton transactions (Cambridge, England : 2003) 20050505 |
| Structure, spectroscopic properties, and reversible solid-to-solid reactions of metal complexes of 5-nitro-pyrimidin-2-olate. | Inorganic chemistry 20050307 |
| [Studies on the structure-activity relationship of allyl substituted oxopyrimidines searching for the novel antagonist or agonist of barbiturates to the sleep mechanism based on the uridine receptor theory--barbituric acid to uridine (part I)]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050101 |
| Genetic and other sources of variation in the activity of serum paraoxonase/diazoxonase in humans: consequences for risk from exposure to diazinon. | Pharmacogenetics and genomics 20050101 |
| Pyrazolo[1,5-a]pyrimidines as estrogen receptor ligands: defining the orientation of a novel heterocyclic core. | Bioorganic & medicinal chemistry letters 20041115 |
| Formation of heterotopic metallacalix[n]arenes (n=3, 4, 6) containing ethylenediaminepalladium(II) metal fragments and 4,7-phenanthroline and 2-pyrimidinolate bridges. Synthesis, structure and host-guest chemistry. | Dalton transactions (Cambridge, England : 2003) 20040907 |
| 2-Pyrimidinone as a probe for studying the EcoRII DNA methyltransferase-substrate interaction. | European journal of biochemistry 20040601 |
| Mineralomimetic sodalite- and muscovite-type coordination frameworks. Dynamic crystal-to-crystal interconversion processes sensitive to ion pair recognition. | Journal of the American Chemical Society 20040317 |
| Synthesis, stability, and protonation studies of a self-complementary dodecamer containing the modified nucleoside 2'-deoxyzebularine. | Biopolymers 20040101 |
| Traceless solid-phase synthesis of nitrogen-containing heterocycles and their biological evaluations as inhibitors of neuronal sodium channels. | Journal of combinatorial chemistry 20040101 |
| Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside (zebularine) at the GCGC recognition domain. | Annals of the New York Academy of Sciences 20031201 |
| Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution. | The Journal of biological chemistry 20030523 |
| Crystallization and preliminary crystallographic analysis of yeast cytosine deaminase. | Acta crystallographica. Section D, Biological crystallography 20030501 |
| Xanthine oxidase-catalyzed metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin. | Drug metabolism and disposition: the biological fate of chemicals 20030401 |
| Antiandrogenic activity and metabolism of the organophosphorus pesticide fenthion and related compounds. | Environmental health perspectives 20030401 |
| In vitro metabolism of fenthion and fenthion sulfoxide by liver preparations of sea bream, goldfish, and rats. | Drug metabolism and disposition: the biological fate of chemicals 20030201 |
| Fluorescent 2-pyrimidinone nucleoside in parallel-stranded DNA. | Nucleosides, nucleotides & nucleic acids 20030101 |
| N3-phenacyluridine as a new type of antinociceptive compound in mice. | Research communications in molecular pathology and pharmacology 20030101 |
| Degradation and sorption of pirimiphos-methyl in two Nigerian soils. | Journal of agricultural and food chemistry 20020925 |
| Metabolism of 2-nitrofluorene, an environmental pollutant, by liver preparations of sea bream, Pagrus major. | Xenobiotica; the fate of foreign compounds in biological systems 20020801 |
| Photochemistry of 2-chloropyrimidine. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020801 |
| Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. | RNA (New York, N.Y.) 20011101 |
| Enzymatic and non-enzymatic reduction of brucine N-oxide by aldehyde oxidase and catalase. | Xenobiotica; the fate of foreign compounds in biological systems 20011101 |
| Extremely high drug-reductase activity based on aldehyde oxidase in monkey liver. | Biological & pharmaceutical bulletin 20010701 |
| Uridine receptor: discovery and its involvement in sleep mechanism. | Sleep 20010501 |
| Hydrogen-bonded complexes of 2-pyridone with centrosymmetric and non-centrosymmetric dicarboxylic acids. | Acta crystallographica. Section C, Crystal structure communications 20010501 |