Home Other Building Blocks 2-Hydroxy-4-methoxybenzophenone

2-Hydroxy-4-methoxybenzophenone

CAS No.:
131-57-7
Catalog Number:
AG003HEF
Molecular Formula:
C14H12O3
Molecular Weight:
228.2433
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
95%
In Stock USA
United States
$13
- +
25g
95%
In Stock USA
United States
$25
- +
100g
95%
In Stock USA
United States
$63
- +
500g
95%
In Stock USA
United States
$188
- +
Product Description
Catalog Number:
AG003HEF
Chemical Name:
2-Hydroxy-4-methoxybenzophenone
CAS Number:
131-57-7
Molecular Formula:
C14H12O3
Molecular Weight:
228.2433
MDL Number:
MFCD00008387
IUPAC Name:
(2-hydroxy-4-methoxyphenyl)-phenylmethanone
InChI:
InChI=1S/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H3
InChI Key:
DXGLGDHPHMLXJC-UHFFFAOYSA-N
SMILES:
COc1ccc(c(c1)O)C(=O)c1ccccc1
EC Number:
205-031-5
UNII:
95OOS7VE0Y
Properties
Complexity:
258  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
228.079g/mol
Formal Charge:
0
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
228.247g/mol
Monoisotopic Mass:
228.079g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
46.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.6  
Literature
Title Journal
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Sunscreen enhancement of UV-induced reactive oxygen species in the skin. Free radical biology & medicine 20061015
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Photopatch testing of 1155 patients: results of the U.K. multicentre photopatch study group. The British journal of dermatology 20061001
Causal agents of photoallergic contact dermatitis diagnosed in the national institute of dermatology of Colombia. Photodermatology, photoimmunology & photomedicine 20060801
Photoallergic contact cheilitis due to oxybenzone found in a lip cosmetic. Contact dermatitis 20060701
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Estrogenic activities of chemicals related to food contact plastics and rubbers tested by the yeast two-hybrid assay. Food additives and contaminants 20060401
Bioactive constituents from Chinese natural medicines. XVII. constituents with radical scavenging effect and new glucosyloxybenzyl 2-isobutylmalates from Gymnadenia conopsea. Chemical & pharmaceutical bulletin 20060401
In vitro permeation of repellent DEET and sunscreen oxybenzone across three artificial membranes. International journal of pharmaceutics 20060309
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Photocontact allergy to oxybenzone and contact allergy to lignocaine and prilocaine. Contact dermatitis 20060301
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Evaluation of the photostability of different UV filter combinations in a sunscreen. International journal of pharmaceutics 20060113
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Separation via flotation, spectrophotometric speciation, and determination of vanadium(IV) in wastes of power stations. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20051101
In vivo bioassay-guided fractionation of marine sediment extracts from the Southern California Bight, USA, for estrogenic activity. Environmental toxicology and chemistry 20051101
Additive estrogenic effects of mixtures of frequently used UV filters on pS2-gene transcription in MCF-7 cells. Toxicology and applied pharmacology 20051015
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Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells. Toxicology in vitro : an international journal published in association with BIBRA 20050901
Photoallergic and allergic reaction to 2-hydroxy-4-methoxybenzophenone (sunscreen) and allergy to cetyl alcohol in cosmetic cream. Contact dermatitis 20050901
Influence of anatomical site and topical formulation on skin penetration of sunscreens. Therapeutics and clinical risk management 20050901
Simultaneous analysis of insect repellent DEET, sunscreen oxybenzone and five relevant metabolites by reversed-phase HPLC with UV detection: application to an in vivo study in a piglet model. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805
[Estrogenic activity of ultraviolet absorbers and the related compounds]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050801
Assay of common sunscreen agents in suncare products by high-performance liquid chromatography on a cyanopropyl-bonded silica column. Journal of pharmaceutical and biomedical analysis 20050615
The effect of packaging materials on the stability of sunscreen emulsions. International journal of pharmaceutics 20050613
In vitro evaluation of concurrent use of commercially available insect repellent and sunscreen preparations. The British journal of dermatology 20050601
Estrogenic activity of cosmetic components in reporter cell lines: parabens, UV screens, and musks. Journal of toxicology and environmental health. Part A 20050227
Occurrence of some organic UV filters in wastewater, in surface waters, and in fish from Swiss Lakes. Environmental science & technology 20050215
Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays. Toxicological sciences : an official journal of the Society of Toxicology 20050201
Unexpected photolysis of the sunscreen octinoxate in the presence of the sunscreen avobenzone. Photochemistry and photobiology 20050101
Sunscreen penetration of human skin and related keratinocyte toxicity after topical application. Skin pharmacology and physiology 20050101
Sunscreens - which and what for? Skin pharmacology and physiology 20050101
Fading of artificial hair color and its prevention by photofilters. Journal of cosmetic science 20050101
Effects of estradiol, benzophenone-2 and benzophenone-3 on the expression pattern of the estrogen receptors (ER) alpha and beta, the estrogen receptor-related receptor 1 (ERR1) and the aryl hydrocarbon receptor (AhR) in adult ovariectomized rats. Toxicology 20041201
Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. The Journal of investigative dermatology 20040701
Recrystallization in different sunscreen formulations after cutaneous application. Journal of cosmetic dermatology 20040701
[First derivative spetrophotometric direct determination of 2-hydroxy-4-methoxybenzo phenone in polyester resin by computer assistant]. Guang pu xue yu guang pu fen xi = Guang pu 20040601
Occurrence of UV filter compounds from sunscreens in surface waters: regional mass balance in two Swiss lakes. Chemosphere 20040501
In-vitro permeation of the insect repellent N,N-diethyl-m-toluamide (DEET) and the sunscreen oxybenzone. The Journal of pharmacy and pharmacology 20040501
Liquid chromatographic assay for common sunscreen agents: application to in vivo assessment of skin penetration and systemic absorption in human volunteers. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040425
Contact and photocontact allergy to ketoprofen. The Belgian experience. Contact dermatitis 20040401
Active ingredients in sunscreens act as topical penetration enhancers for the herbicide 2,4-dichlorophenoxyacetic acid. Toxicology and applied pharmacology 20040315
In vitro estrogenicity of resin composites. Journal of dental research 20040301
Golmaenone, a new diketopiperazine alkaloid from the marine-derived fungus Aspergillus sp. Chemical & pharmaceutical bulletin 20040301
Polymeric nanoparticles composed of fatty acids and polyvinylalcohol for topical application of sunscreens. The Journal of pharmacy and pharmacology 20040301
Effect of oxybenzone on PGE2-production in vitro and on plaque and gingivitis in vivo. Journal of clinical periodontology 20040201
Influence of cyclodextrin complexation on the in vivo photoprotective effects of oxybenzone. Drug development and industrial pharmacy 20040101
Microbial transformation of terreusinone, an ultraviolet-A (UV-A) protecting dipyrroloquinone, by Streptomyces sp. Chemical & pharmaceutical bulletin 20031201
Facial erythema as a result of benzophenone allergy. Journal of the American Academy of Dermatology 20031101
Non-invasive in vivo determination of UVA efficacy of sunscreens using diffuse reflectance spectroscopy. Photodermatology, photoimmunology & photomedicine 20030801
UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay. Toxicological sciences : an official journal of the Society of Toxicology 20030701
North American Contact Dermatitis Group patch-test results, 1998 to 2000. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20030601
Determination of butyl methoxydibenzoylmethane, benzophenone-3, octyl dimethyl PABA and octyl methoxycinnamate in lipsticks. International journal of cosmetic science 20030601
TiO2-promoted mineralization of organic sunscreens in water suspension and sodium dodecyl sulfate micelles. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20030501
Contact urticaria, allergic contact dermatitis, and photoallergic contact dermatitis from oxybenzone. American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20030301
Skin penetration and sun protection factor of five UV filters: effect of the vehicle. Skin pharmacology and applied skin physiology 20030101
An in vitro systematic spectroscopic examination of the photostabilities of a random set of commercial sunscreen lotions and their chemical UVB/UVA active agents. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021201
Percutaneous absorption of benzophenone-3, a common component of topical sunscreens. Clinical and experimental dermatology 20021101
[Photocontact dermatitis due to ketoprofen and photosensitization to tetrachlorosalicylanide and to Fenticlor(R)]. Annales de dermatologie et de venereologie 20021001
Influence of hydroxypropyl-beta-cyclodextrin on the transdermal permeation and skin accumulation of oxybenzone. Drug development and industrial pharmacy 20021001
Gas chromatographic determination of 2-hydroxy-4-methoxybenzophenone and octyldimethyl-p-aminobenzoic acid sunscreen agents in swimming pool and bathing waters by solid-phase microextraction. Journal of chromatography. A 20020823
The development of an improved carrier system for sunscreen formulations based on crystalline lipid nanoparticles. International journal of pharmaceutics 20020821
Solid lipid nanoparticles as carrier for sunscreens: in vitro release and in vivo skin penetration. Journal of controlled release : official journal of the Controlled Release Society 20020617
[Cross-reaction potentials of ketoprofen]. Orvosi hetilap 20020512
Photosensitive dermatitis due to sunscreen allergy in a child. The Australasian journal of dermatology 20020501
Benzophenone-3: rapid prediction and evaluation using non-invasive methods of in vivo human penetration. Journal of pharmaceutical and biomedical analysis 20020401
2-Acetylindan-1,3-dione and its Cu(2+) and Zn(2+) complexes as promising sunscreen agents. International journal of cosmetic science 20020401
Metabolism of 2-hydroxy-4-methoxybenzophenone in isolated rat hepatocytes and xenoestrogenic effects of its metabolites on MCF-7 human breast cancer cells. Chemico-biological interactions 20020220
Influence of Transcutol CG on the skin accumulation and transdermal permeation of ultraviolet absorbers. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020101
A new model using liposomes that allow to distinguish between absorption and oxidative properties of sunscreens. Photochemistry and photobiology 20020101
Severe contact urticaria and anaphylaxis from benzophenone-3(2-hydroxy 4-methoxy benzophenone). Contact dermatitis 20020101
[Results of a French nationwide survey of cutaneous side effects of ketoprofen gel reported between September 1996 and August 2000]. Therapie 20020101
[Do sunscreen lotions have any endocrine effects?]. Annales de dermatologie et de venereologie 20020101
Thioredoxin reductase - its role in epidermal redox status. Journal of photochemistry and photobiology. B, Biology 20011115
Report of 19 cases of photoallergic contact dermatitis to sunscreens seen at the Skin and Cancer Foundation. The Australasian journal of dermatology 20011101
There is no influence of a temperature rise on in vivo adsorption of UV filters into the stratum corneum. Journal of dermatological science 20011001
Solid lipid nanoparticles (SLN)--a novel carrier for UV blockers. Die Pharmazie 20011001
Photoallergic contact dermatitis is uncommon. The British journal of dermatology 20011001
[Photoaggravated contact allergy and contact photoallergy caused by ketoprofen: 19 cases]. Annales de dermatologie et de venereologie 20011001
LC separation of calcipotriol from its photodegradation products and protection possibilities using adjuvants. Journal of pharmaceutical and biomedical analysis 20010801
Sequential injection spectrophotometric determination of oxybenzone in lipsticks. The Analyst 20010801
Comments on 'In vitro and in vivo estrogenicity of UV screens'. Environmental health perspectives 20010801
Skin permeation of two different benzophenone derivatives from various vehicles. International journal of cosmetic science 20010801
Determination of the UV filters worldwide authorised in sunscreens by high-performance liquid chromatography. Use of cyclodextrins as mobile phase modifier. Journal of chromatography. A 20010706
Can increasing the viscosity of formulations be used to reduce the human skin penetration of the sunscreen oxybenzone? The Journal of investigative dermatology 20010701
Simultaneous photocontact sensitivity to ketoprofen and oxybenzone. Contact dermatitis 20010601
Photosensitization of the sunscreen octyl p-dimethylaminobenzoate by UVA in human melanocytes but not in keratinocytes. Photochemistry and photobiology 20010601
Determination of UV-filters in sunscreens by HPLC. Fresenius' journal of analytical chemistry 20010401
Efficient flow injection and sequential injection methods for spectrophotometric determination of oxybenzone in sunscreens based on reaction with Ni(II). Fresenius' journal of analytical chemistry 20010401
[Allergies to ketoprofen gels]. Presse medicale (Paris, France : 1983) 20010331
Anaphylaxis to oxybenzone, a frequent constituent of sunscreens. The Journal of allergy and clinical immunology 20010301
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. Chemical research in toxicology 20010301
In vitro and in vivo estrogenicity of UV screens. Environmental health perspectives 20010301
Metabolic effects of dental resin components in vitro detected by NMR spectroscopy. Journal of dental research 20010301
Five cases of photocontact dermatitis due to topical ketoprofen: photopatch testing and cross-reaction study. Photodermatology, photoimmunology & photomedicine 20010201
Analgesic-induced asthma caused by 2.0% ketoprofen adhesive agents, but not by 0.3% agents. Internal medicine (Tokyo, Japan) 20010201
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