Home Other Building Blocks 2-Hydroxy-4-(methylthio)butyric acid

2-Hydroxy-4-(methylthio)butyric acid

CAS No.:
583-91-5
Catalog Number:
AG003HE5
Molecular Formula:
C5H10O3S
Molecular Weight:
150.1961
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
1 week
United States
$405
- +
Product Description
Catalog Number:
AG003HE5
Chemical Name:
2-Hydroxy-4-(methylthio)butyric acid
CAS Number:
583-91-5
Molecular Formula:
C5H10O3S
Molecular Weight:
150.1961
MDL Number:
MFCD00070490
IUPAC Name:
2-hydroxy-4-methylsulfanylbutanoic acid
InChI:
InChI=1S/C5H10O3S/c1-9-3-2-4(6)5(7)8/h4,6H,2-3H2,1H3,(H,7,8)
InChI Key:
ONFOSYPQQXJWGS-UHFFFAOYSA-N
SMILES:
CSCCC(C(=O)O)O
EC Number:
209-523-0
Properties
Complexity:
94.2  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
150.035g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
150.192g/mol
Monoisotopic Mass:
150.035g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
82.8A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2  
Literature
Title Journal
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Bioavailability of methionine hydroxy analog-calcium salt relative to DL-methionine to support nitrogen retention and growth in starter pigs. Animal : an international journal of animal bioscience 20121101
Effect of supplementary concentrate type on nitrogen partitioning in early lactation dairy cows offered perennial ryegrass-based pasture. Journal of dairy science 20120801
Effects of graded levels of dietary methionine hydroxy analogue on immune response and antioxidant status of immune organs in juvenile Jian carp (Cyprinus carpio var. Jian). Fish & shellfish immunology 20120501
Application of ultra-performance liquid chromatography coupled with mass spectrometry to metabonomic study on spontaneously hypertensive rats and intervention effects of Ping Gan prescription. Journal of separation science 20120201
Effects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens. The British journal of nutrition 20111201
Effects of dietary supplementation of methionine and its hydroxy analog DL-2-hydroxy-4-methylthiobutanoic acid on growth performance, plasma hormone levels, and the redox status of broiler chickens exposed to high temperatures. Poultry science 20111001
Effect of forage source and a supplementary methionine hydroxy analog on nitrogen balance in lactating dairy cows offered a low crude protein diet. Journal of dairy science 20111001
Comparative in vivo antioxidant capacity of DL-2-hydroxy-4-methylthiobutanoic acid (HMTBA) and DL-methionine in male mice fed a high-fat diet. Journal of the science of food and agriculture 20110901
Intestinal cell conversion of DL-2-hydroxy-(4-methylthio)butanoic acid in vitro: dietary up-regulation by this methionine precursor. The British journal of nutrition 20110801
The site of intestinal disappearance of DL-methionine and methionine hydroxy analog differs in pigs. Journal of animal science 20110501
Effect of feeding different sources of rumen-protected methionine on milk production and N-utilization in lactating dairy cows. Journal of dairy science 20110401
Metabolism of 2-hydroxy-4-(methylthio)butanoate (HMTBA) in lactating dairy cows. Journal of dairy science 20110301
Effects of dietary supplementation of methionine and lysine on milk production and nitrogen utilization in dairy cows. Journal of dairy science 20100801
Effects of adding liquid DL-methionine hydroxy analogue-free acid to drinking water on growth performance and small intestinal morphology of nursery pigs. Journal of animal physiology and animal nutrition 20100601
Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availability. The British journal of nutrition 20100301
Short communication: transport of 2-hydroxy-4-methyl-thio-butanoic isopropyl ester by rumen epithelium in vitro. Journal of dairy science 20100101
Effects of providing two forms of supplemental methionine to periparturient Holstein dairy cows on feed intake and lactational performance. Journal of dairy science 20091001
Apparent absorption of methionine and 2-hydroxy-4-methylthiobutanoic acid from gastrointestinal tract of conventional and gnotobiotic pigs. Animal : an international journal of animal bioscience 20091001
Molecular analysis of microbial community structure in the chicken ileum following organic acid supplementation. Veterinary microbiology 20090612
Effects of 2-hydroxy-4-methylthiobutyrate on portal plasma flow and net portal appearance of amino acids in piglets. Amino acids 20090301
Effects of 2-hydroxy-4-(methylthio)-butanoic acid on performance and carcass characteristics of finishing beef cattle and on fermentation in continuous culture. Journal of animal science 20080801
Effects of liquid DL-2-hydroxy-4-methylthio butanoic acid on growth performance and immune responses in broiler chickens. Poultry science 20080701
Partial Na+ dependence of DL-2-hydroxy-4-(methylthio)butanoic acid uptake in the chicken small intestine. Poultry science 20080701
The effect of several organic acids on phytate phosphorus hydrolysis in broiler chicks. Poultry science 20080401
Effect of different dietary methionine sources on intestinal microbial populations in broiler chickens. Poultry science 20071101
Effects of rumen-undegradable protein sources and supplemental 2-hydroxy-4-(methylthio)-butanoic acid and lysine-HCl on lactation performance in dairy cows. Journal of dairy science 20071101
Effect of excess methionine and methionine hydroxy analogue on growth performance and plasma homocysteine of growing Pekin ducks. Poultry science 20070901
Short communication: Absorption of 2-hydroxy-4-methylthiobutanoate in dairy cows. Journal of dairy science 20070601
Determining the methionine activity of Mintrex organic trace minerals in broiler chicks by using radiolabel tracing or growth assay. Poultry science 20070501
Impact of feeding 2-hydroxy-4-(methylthio)butanoic acid and DL-methionine supplemented maize-soybean-rapeseed meal diets on growth performance and carcase quality of broilers. British poultry science 20070401
Evidence of a different dose response in turkeys when fed 2-hydroxy-4(methylthio) butanoic acid versus DL-methionine. Poultry science 20070301
Assessment of ruminal bacterial populations and protozoal generation time in cows fed different methionine sources. Journal of dairy science 20070201
Multidimensional chromatographic approach applied to the identification of novel aroma compounds in wine. Identification of ethyl cyclohexanoate, ethyl 2-hydroxy-3-methylbutyrate and ethyl 2-hydroxy-4-methylpentanoate. Journal of chromatography. A 20061229
No evidence for different dose responses of commercial methionine sources in broilers. Poultry science 20061201
Conversion of the methionine hydroxy analogue DL-2-hydroxy-(4-methylthio) butanoic acid to sulfur-containing amino acids in the chicken small intestine. Poultry science 20061101
Effect of different forms of methionine on lactational performance of dairy cows. Journal of dairy science 20061101
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age. Poultry science 20061001
Absorption and digestive tract metabolism of 2-hydroxy-4-methylthiobutanoic acid in lambs. Journal of dairy science 20060901
Concentrations of putrescine, spermidine, and spermine in duodenum and pancreas as affected by the ratio of arginine to lysine and source of methionine in broilers under heat stress. Poultry science 20060801
Evidence for 2-hydroxy-4(methylthio) butanoic acid and DL-methionine having different dose responses in growing broilers. Poultry science 20060801
Effects of dietary supplementation of DL-methionine or 2-hydroxy-4-(methylthio)-butanoic acid on food intake, nutrient digestibility, nitrogen balance, and urinary and blood metabolites in healthy, growing dogs. Archives of animal nutrition 20060801
Estimation of the true ileal digestible lysine and sulfur amino acid requirement and comparison of the bioefficacy of 2-hydroxy-4-(methylthio)butanoic acid and DL-methionine in eleven- to twenty-six-kilogram nursery pigs. Journal of animal science 20060701
Appropriate statistical methods to compare dose responses of methionine sources. Poultry science 20060501
A multiple regression model approach to contrast the performance of 2-hydroxy-4-methylthio butanoic acid and DL-methionine supplementation tested in broiler experiments and reported in the literature. Poultry science 20060401
Hepatic metabolism of 2-hydroxy-4-methylthiobutyrate in growing lambs. Journal of dairy science 20060301
Absorption of 2-hydroxy-4-methylthiobutyrate and conversion to methionine in lambs. Journal of dairy science 20060301
Oligomers are not the limiting factor in the absorption of DL-2-hydroxy-4-(methylthio)butanoic acid in the chicken small intestine. Poultry science 20060101
Estimation of the ideal ratio of true ileal digestible sulfur amino acids:lysine in 8- to 26-kg nursery pigs. Journal of animal science 20051101
Methionine availability in plasma of dairy cows supplemented with methionine hydroxy analog isopropyl ester. Journal of dairy science 20051001
The effects of various organic acids on phytate phosphorus utilization in chicks. Poultry science 20050901
Comparative in vitro and in vivo absorption of 2-hydroxy-4(methylthio) butanoic acid and methionine in the broiler chicken. Poultry science 20050901
Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) and its isopropyl ester on milk production and composition by Holstein cows. Journal of dairy science 20050701
Metal chelates of 2-hydroxy-4-methylthiobutanoic acid in animal feeding. Part 2: Further characterizations, in vitro and in vivo investigations. Journal of inorganic biochemistry 20050201
The influence of dietary sodium chloride, arginine:lysine ratio, and methionine source on apparent ileal digestibility of arginine and lysine in acutely heat-stressed broilers. Poultry science 20050201
Determination of rumen degradability and ruminal effects of three sources of methionine in lactating cows. Journal of dairy science 20050101
Estimation of bioavailability of DL-methionine hydroxy analogue relative to DL-methionine in layers with exponential and slope-ratio models. Poultry science 20040901
Effects of zinc and sodium monensin on ruminal degradation of lysine-HCl and liquid 2-hydroxy-4-methylthiobutanoic acid. Journal of dairy science 20040801
Feeding 2-hydroxy-4-(methylthio)-butanoic acid to periparturient dairy cows improves milk production but not hepatic metabolism. Journal of dairy science 20040401
Catabolism of volatile sulfur compounds precursors by Brevibacterium linens and Geotrichum candidum, two microorganisms of the cheese ecosystem. Journal of biotechnology 20031106
Adaptations in body muscle and fat in transition dairy cattle fed differing amounts of protein and methionine hydroxy analog. Journal of dairy science 20031101
Effects of 2-hydroxy-4-(methylthio) butanoic acid (HMB) on microbial growth in continuous culture. Journal of dairy science 20030801
Absorption of methionine and 2-hydroxy-4-methylthiobutoanic acid in conventional and germ-free chickens. Poultry science 20030701
Metal chelates of 2-hydroxy-4-methylthiobutanoic acid in animal feeding: preliminary investigations on stability and bioavailability. Journal of inorganic biochemistry 20030601
Enzymatic synthesis and characterization of l-methionine and 2-hydroxy-4-(methylthio)butanoic acid (HMB) co-oligomers. Journal of agricultural and food chemistry 20030423
Effects of calcium salts of fatty acids and calcium salt of methionine hydroxy analogue on plasma prostaglandin F2alpha metabolite and milk fatty acid profiles in late lactation Holstein-Friesian cows. Theriogenology 20021101
Relative effectiveness of methionine hydroxy analog compared to DL-methionine in broiler chickens. Poultry science 20020601
Rumen degradation and availability of various amounts of liquid methionine hydroxy analog in lactating dairy cows. Journal of dairy science 20020401
[The feed value in growing pigs of a new cultivar of field beans (Vicia faba L.) supplemented with DL-methionine or DL-methionine-hydroxyanalog]. Journal of animal physiology and animal nutrition 20020201
Uptake of DL-2-hydroxy-4-methylthio-butanoic acid (DL-HMB) in the broiler liver in vivo. Poultry science 20011101
The hepatic extraction of plasma free amino acids and response to hepatic portal venous infusion of methionine sources in anesthetized SCWL males (Gallus domesticus). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010901
Lactobacillus casei and Lactobacillus plantarum initiate catabolism of methionine by transamination. Journal of applied microbiology 20010601
Effects of alimet on nutrient digestibility, bacterial protein synthesis, and ruminal disappearance during continuous culture. Journal of dairy science 20010101
Properties