Home Other Building Blocks 2-Chloroquinoline

2-Chloroquinoline

CAS No.:
612-62-4
Catalog Number:
AG003H3J
Molecular Formula:
C9H6ClN
Molecular Weight:
163.6036
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
96%
In Stock USA
United States
$25
- +
25g
96%
In Stock USA
United States
$75
- +
100g
96%
In Stock USA
United States
$244
- +
Product Description
Catalog Number:
AG003H3J
Chemical Name:
2-Chloroquinoline
CAS Number:
612-62-4
Molecular Formula:
C9H6ClN
Molecular Weight:
163.6036
MDL Number:
MFCD00006741
IUPAC Name:
2-chloroquinoline
InChI:
InChI=1S/C9H6ClN/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H
InChI Key:
OFUFXTHGZWIDDB-UHFFFAOYSA-N
SMILES:
Clc1ccc2c(n1)cccc2
EC Number:
210-317-8
UNII:
UX7RIN8GEW
NSC Number:
6163
Properties
Complexity:
138  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
163.019g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
163.604g/mol
Monoisotopic Mass:
163.019g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
12.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.7  
Literature
Title Journal
Synthesis and 3D-QSAR analysis of 2-chloroquinoline derivatives as H37 RV MTB inhibitors. Chemical biology & drug design 20131201
Prion inhibition with multivalent PrPSc binding compounds. Biomaterials 20121001
Discovery of a new antileishmanial hit in 8-nitroquinoline series. European journal of medicinal chemistry 20120801
C-C bond formation at C-2 of a quinoline ring: synthesis of 2-(1H-indol-3-yl)quinoline-3-carbonitrile derivatives as a new class of PDE4 inhibitors. Bioorganic & medicinal chemistry 20120401
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2). Journal of medicinal chemistry 20120308
A physico-chemical and biological study of novel chitosan-chloroquinoline derivative for biomedical applications. International journal of biological macromolecules 20111001
Effects of highly active novel artemisinin-chloroquinoline hybrid compounds on β-hematin formation, parasite morphology and endocytosis in Plasmodium falciparum. Biochemical pharmacology 20110801
Antiprotozoal activity of chloroquinoline based chalcones. European journal of medicinal chemistry 20110501
[Rationale for hygienic regulations for the use of a new mixed herbicide antidote]. Gigiena i sanitariia 20110101
N-[(2-Chloro-3-quinol-yl)meth-yl]-4-fluoro-aniline. Acta crystallographica. Section E, Structure reports online 20101001
1-{6-Chloro-2-[(2-chloro-8-methyl-3-quinol-yl)meth-oxy]-4-phenyl-quinolin-3-yl}ethanone. Acta crystallographica. Section E, Structure reports online 20100801
4-Chloro-2,5-dimethyl-quinoline. Acta crystallographica. Section E, Structure reports online 20100801
1-{6-Chloro-2-[(2-chloro-3-quinol-yl)meth-oxy]-4-phenyl-3-quinol-yl}ethan-1-one. Acta crystallographica. Section E, Structure reports online 20100701
1-{6-Chloro-2-[(2-chloro-6-methyl-quinolin-3-yl)meth-oxy]-4-phenyl-quinolin-3-yl}ethanone. Acta crystallographica. Section E, Structure reports online 20100701
Synthesis and in vitro biological evaluation of carbon-11-labeled quinoline derivatives as new candidate PET radioligands for cannabinoid CB2 receptor imaging. Bioorganic & medicinal chemistry 20100315
Chemoenzymatic synthesis of chiral 2,2'-bipyridine ligands and their N-oxide derivatives: applications in the asymmetric aminolysis of epoxides and asymmetric allylation of aldehydes. Organic & biomolecular chemistry 20100307
The identification of nonpeptide neurotensin receptor partial agonists from the potent antagonist SR48692 using a calcium mobilization assay. Bioorganic & medicinal chemistry letters 20090301
Chemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary culture. PloS one 20090101
Azaarene cis-dihydrodiol-derived 2,2'-bipyridine ligands for asymmetric allylic oxidation and cyclopropanation. Chemical communications (Cambridge, England) 20081121
N-(2-Chloro-quinolin-3-ylmethyl-ene)aniline. Acta crystallographica. Section E, Structure reports online 20080101
Sensitive and rapid liquid chromatography/tandem mass spectrometric assay for the quantification of piperaquine in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101
Sensitive and rapid liquid chromatography/tandem mass spectrometric assay for the quantification of chloroquine in dog plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601
Chloroquinolines block antibiotic efflux pumps in antibiotic-resistant Enterobacter aerogenes isolates. International journal of antimicrobial agents 20060601
Use of highly active palladium-phosphinous acid catalysts in Stille, Heck, amination, and thiation reactions of chloroquinolines. The Journal of organic chemistry 20030905
Novel synthesis of 2-chloroquinolines from 2-vinylanilines in nitrile solvent. The Journal of organic chemistry 20021101
Synthesis of 1,4-disubstituted 2-methylpiperazine derivatives, new 5-HT(1A) receptor ligands. Acta poloniae pharmaceutica 20010101
Properties