Home Other Building Blocks 2-Chloroacetanilide

2-Chloroacetanilide

CAS No.:
587-65-5
Catalog Number:
AG003H2Y
Molecular Formula:
C8H8ClNO
Molecular Weight:
169.6082
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$19
- +
5g
98%
In Stock USA
United States
$57
- +
10g
98%
In Stock USA
United States
$94
- +
25g
98%
In Stock USA
United States
$188
- +
100g
98%
In Stock USA
United States
$563
- +
Product Description
Catalog Number:
AG003H2Y
Chemical Name:
2-Chloroacetanilide
CAS Number:
587-65-5
Molecular Formula:
C8H8ClNO
Molecular Weight:
169.6082
MDL Number:
MFCD00018887
IUPAC Name:
2-chloro-N-phenylacetamide
InChI:
InChI=1S/C8H8ClNO/c9-6-8(11)10-7-4-2-1-3-5-7/h1-5H,6H2,(H,10,11)
InChI Key:
VONWPEXRCLHKRJ-UHFFFAOYSA-N
SMILES:
ClCC(=O)Nc1ccccc1
EC Number:
209-604-0
UNII:
2R6RM9R0W8
NSC Number:
311
Properties
Complexity:
132  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
169.029g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
169.608g/mol
Monoisotopic Mass:
169.029g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
29.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.6  
Literature
Title Journal
Butachlor induced dissipation of mitochondrial membrane potential, oxidative DNA damage and necrosis in human peripheral blood mononuclear cells. Toxicology 20121208
Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis. Journal of medicinal chemistry 20120726
Enantioselective phytotoxicity of metolachlor against maize and rice roots. Journal of hazardous materials 20120530
Assessing the impact of chloroacetanilide herbicides and their metabolites on periphyton in the Leyre River (SW France) via short term growth inhibition tests on autochthonous diatoms. Journal of environmental monitoring : JEM 20120501
The greening of pesticide-environment interactions: some personal observations. Environmental health perspectives 20120401
Acute oral poisoning due to chloracetanilide herbicides. Journal of Korean medical science 20120201
Cumulative risk assessment: an overview of methodological approaches for evaluating combined health effects from exposure to multiple environmental stressors. International journal of environmental research and public health 20120201
The ascorbate-glutathione-α-tocopherol triad in abiotic stress response. International journal of molecular sciences 20120101
Does S-metolachlor affect the performance of Pseudomonas sp. strain ADP as bioaugmentation bacterium for atrazine-contaminated soils? PloS one 20120101
Discriminating multiple impacts of biogas residues amendment in selectively decontaminating chloroacetanilide herbicides. Journal of agricultural and food chemistry 20111026
Pesticide processing potential in prairie pothole porewaters. Environmental science & technology 20110815
Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. Environmental health perspectives 20110801
Urinary biomarkers of prenatal atrazine exposure and adverse birth outcomes in the PELAGIE birth cohort. Environmental health perspectives 20110701
Novel liquid-liquid-solid microextraction method with molecularly imprinted polymer-coated stainless steel fiber for aqueous sample pretreatment. Journal of chromatography. A 20110624
Expansion mechanisms and functional divergence of the glutathione s-transferase family in sorghum and other higher plants. DNA research : an international journal for rapid publication of reports on genes and genomes 20110201
Erythema multiforme major due to occupational exposure to the herbicides alachlor and butachlor. Emergency medicine Australasia : EMA 20110201
RMDAP: a versatile, ready-to-use toolbox for multigene genetic transformation. PloS one 20110101
Parts-per-trillion LC-MS(Q) analysis of herbicides and transformation products in surface water. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20110101
Expression patterns of glutathione transferase gene (GstI) in maize seedlings under juglone-induced oxidative stress. International journal of molecular sciences 20110101
Evaluation of DNA damage in agricultural workers exposed to pesticides using single cell gel electrophoresis (comet) assay. Indian journal of human genetics 20110101
Influence of surfactants on the sorption of two chloroacetanilide in an Romanian chernozem soil. Communications in agricultural and applied biological sciences 20110101
Monitoring of pesticide residues in dairy cattle farms from NW Spain. Journal of environmental monitoring : JEM 20101006
Overexpression of a specific soybean GmGSTU4 isoenzyme improves diphenyl ether and chloroacetanilide herbicide tolerance of transgenic tobacco plants. Journal of biotechnology 20101001
Molecularly imprinted polymer coated on stainless steel fiber for solid-phase microextraction of chloroacetanilide herbicides in soybean and corn. Journal of chromatography. A 20100917
New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. European journal of medicinal chemistry 20100701
Comparison of current-use pesticide and other toxicant urinary metabolite levels among pregnant women in the CHAMACOS cohort and NHANES. Environmental health perspectives 20100601
A composite transcriptional signature differentiates responses towards closely related herbicides in Arabidopsis thaliana and Brassica napus. Plant molecular biology 20100301
Monocyclic aromatic amines as potential human carcinogens: old is new again. Carcinogenesis 20100101
Childhood brain tumors, residential insecticide exposure, and pesticide metabolism genes. Environmental health perspectives 20100101
Transcriptional responses to polycyclic aromatic hydrocarbon-induced stress in Arabidopsis thaliana reveal the involvement of hormone and defense signaling pathways. BMC plant biology 20100101
Dechlorination of chloroacetanilide herbicides by plant growth regulator sodium bisulfite. Water research 20090801
Comparison of rat olfactory mucosal responses to carcinogenic and non-carcinogenic chloracetanilides. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090601
Effects of alachlor on biochemical parameters of the freshwater fish, Channa punctatus (Bloch). Journal of environmental biology 20090501
Studies on histopathological changes in the gill, liver and kidney of Channa punctatus (Bloch) exposed to Alachlor. Journal of environmental biology 20090301
Investigation of the matrix effects on a HPLC-ESI-MS/MS method and application for monitoring triazine, phenylurea and chloroacetanilide concentrations in fresh and estuarine waters. Journal of environmental monitoring : JEM 20090101
The watershed as a conceptual framework for the study of environmental and human health. Environmental health insights 20090101
Degradation of acetochlor by four microbial communities. Bioresource technology 20081101
Relative effects of surfactants and humidity on soil/air desorption of chloroacetanilide and dinitroaniline herbicides. Environmental science & technology 20080915
Catabolism of glutathione conjugates in Arabidopsis thaliana. Role in metabolic reactivation of the herbicide safener fenclorim. The Journal of biological chemistry 20080725
Specific interactions of chloroacetanilide herbicides with human ABC transporter proteins. Toxicology 20080603
2-Chloro-N-phenyl-acetamide. Acta crystallographica. Section E, Structure reports online 20080601
Comparative cytotoxicity of alachlor, acetochlor, and metolachlor herbicides in isolated rat and cryopreserved human hepatocytes. Journal of biochemical and molecular toxicology 20080201
2-Chloro-N-(2,3-dichloro-phen-yl)acetamide. Acta crystallographica. Section E, Structure reports online 20080201
Direct observation of aminyl radical intermediate during single-crystal to single-crystal photoinduced Orton rearrangement. The journal of physical chemistry. B 20070906
Identification of human urinary metabolites of acetochlor in exposed herbicide applicators by high-performance liquid chromatography-tandem mass spectrometry. Journal of exposure science & environmental epidemiology 20070901
Determination of enzyme kinetics and glutathione conjugates of chlortetracycline and chloroacetanilides using liquid chromatography-mass spectrometry. The Analyst 20070701
Effects of relative humidity on chloroacetanilide and dinitroaniline herbicide desorption from agricultural PM2.5 on quartz fiber filters. Environmental science & technology 20070601
Analysis of chloroacetanilide herbicides in water samples by solid-phase microextraction coupled with gas chromatography-mass spectrometry. Analytica chimica acta 20070515
Cytotoxicity of chloroacetanilide herbicide alachlor in HepG2 cells independent of CYP3A4 and CYP3A7. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070501
Effect of humic acids on photodegradation of chloroacetanilide herbicides under UV irradiation. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20070201
In vitro alachlor effects on reactive oxygen species generation, motility patterns and apoptosis markers in human spermatozoa. Reproductive toxicology (Elmsford, N.Y.) 20070101
Characterization of glutathione conjugates of chloroacetanilide pesticides using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry. Rapid communications in mass spectrometry : RCM 20070101
Study on the biochemical characterization of herbicide detoxification enzyme, glutathione S-transferase. BioFactors (Oxford, England) 20070101
Characterization of two Arabidopsis thaliana glutathione S-transferases. Plant cell reports 20060901
Dechlorinating chloroacetanilide herbicides by dithionite-treated aquifer sediment and surface soil. Environmental science & technology 20060501
Degradation of chloroacetanilide herbicides by anodic fenton treatment. Journal of agricultural and food chemistry 20060405
Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact? Environmental health perspectives 20060401
Development of EPA method 535 for the determination of chloroacetanilide and other acetamide herbicide degradates in drinking water by solid-phase extraction and liquid chromatography/tandem mass spectrometry. Journal of AOAC International 20060101
Phytoremediation of metolachlor by transgenic rice plants expressing human CYP2B6. Journal of agricultural and food chemistry 20051116
Development of transgenic tobacco plants overexpressing maize glutathione S-transferase I for chloroacetanilide herbicides phytoremediation. Biomolecular engineering 20051001
Correlation analyses for bimolecular nucleophilic substitution reactions of chloroacetanilide herbicides and their structural analogs with environmentally relevant nucleophiles. Environmental toxicology and chemistry 20051001
Kinetic analysis of maize glutathione S-transferase I catalysing the detoxification from chloroacetanilide herbicides. Planta 20050901
Dissipation of acetochlor and its distribution in surface and sub-surface soil fractions during laboratory incubations. Pest management science 20050601
An analytical method for the simultaneous determination of butachlor and benoxacor in wheat and soil. Journal of agricultural and food chemistry 20050601
Gene expression and microscopic analysis of Arabidopsis exposed to chloroacetanilide herbicides and explosive compounds. A phytoremediation approach. Plant physiology 20050601
[Study on the reaction mechanism of chloroacetanilide herbicides with urease using fluorescence spectrum and high-performance liquid chromatography]. Guang pu xue yu guang pu fen xi = Guang pu 20050301
The acetochlor registration partnership surface water monitoring program for four corn herbicides. Journal of environmental quality 20050101
Chemopreventive properties of trans-resveratrol against the cytotoxicity of chloroacetanilide herbicides in vitro. International journal of hygiene and environmental health 20050101
Analysis of the chloroacetanilide herbicides in water using SPME with CAR/PDMS and GC/ECD. Journal of AOAC International 20050101
Reduction of alachlor-induced olfactory mucosal neoplasms by the matrix metalloproteinase inhibitor Ro 28-2653. Toxicologic pathology 20050101
Transformation of herbicide propachlor by an agrochemical thiourea. Environmental science & technology 20041215
Chloroacetanilide herbicide metabolites in Wisconsin groundwater: 2001 survey results. Environmental science & technology 20041015
Novel analogues of sydnone: synthesis, characterization and antibacterial evaluation. Archiv der Pharmazie 20040801
Development of a sensitivity enhanced multiplexed fluorescence covalent microbead immunosorbent assay (FCMIA) for the measurement of glyphosate, atrazine and metolachlor mercapturate in water and urine. Analytical and bioanalytical chemistry 20040601
Kinetics and mechanism of the nucleophilic displacement reactions of chloroacetanilide herbicides: investigation of alpha-substituent effects. Journal of agricultural and food chemistry 20040519
Herbicide concentrations in the Mississippi River Basin-the importance of chloroacetanilide herbicide degradates. The Science of the total environment 20040405
Antioxidant perturbations in the olfactory mucosa of alachlor-treated rats. Biochemical pharmacology 20031101
Predictability of combined effects of eight chloroacetanilide herbicides on algal reproduction. Pest management science 20031001
Adsorption mechanism of chloroacetanilide herbicides to modified montmorillonite. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20030901
The fate of chloroacetanilide herbicides and their degradation products in the Nzoia Basin, Kenya. Ambio 20030901
Cloning, characterization and regulation of a family of phi class glutathione transferases from wheat. Plant molecular biology 20030601
Persistence, mobility, efficacy and activity of chloroacetanilide herbicide formulation under greenhouse and field experiments. Environmental pollution (Barking, Essex : 1987) 20030101
The herbicide metolachlor induces liver cytochrome P450s 2B1/2 and 3A1/2, but not thyroxine-uridine dinucleotide phosphate glucuronosyltransferase and associated thyroid gland activity. International journal of toxicology 20030101
Stream transport of herbicides and metabolites in a tile-drained, agricultural watershed. Journal of environmental quality 20030101
Induction of glutathione S-transferases in Arabidopsis by herbicide safeners. Plant physiology 20021101
Nucleophilic aliphatic substitution reactions of propachlor, alachlor, and metolachlor with bisulfide (HS-) and polysulfides (Sn2-). Environmental science & technology 20021001
Herbicide safeners: uses, limitations, metabolism, and mechanisms of action. Chemosphere 20020901
Determination of triazine and chloroacetanilide herbicides in soils by microwave-assisted extraction (MAE) coupled to gas chromatographic analysis with either GC-NPD or GC-MS. Journal of agricultural and food chemistry 20020828
Analytical method for the determination of metolachlor, acetochlor, alachlor, dimethenamid, and their corresponding ethanesulfonic and oxanillic acid degradates in water using SPE and LC/ESI-MS/MS. Analytical chemistry 20020801
Influence of herbicide structure, clay acidity, and humic acid coating on acetanilide herbicide adsorption on homoionic clays. Journal of agricultural and food chemistry 20020703
Adsorption of chloroacetanilide herbicides on soil and its components. III. Influence of clay acidity, humic acid coating and herbicide structure on acetanilide herbicide adsorption on homoionic clays. Journal of environmental sciences (China) 20020401
Developmental disorders in embryos of the frog Xenopus laevis induced by chloroacetanilide herbicides and their degradation products. Environmental toxicology and chemistry 20020201
Plant glutathione transferases. Genome biology 20020101
Metolachlor dechlorination by zerovalent iron during unsaturated transport. Journal of environmental quality 20020101
Evaluation of enzyme-linked immunoassays for the determination of chloroacetanilides in water and soils. Environmental science & technology 20011015
Development of sampling and analytical methods for concerted determination of commonly used chloroacetanilide, chlorotriazine, and 2,4-D herbicides in hand-wash, dermal-patch, and air samples. Applied occupational and environmental hygiene 20010601
Enhanced tolerance of transgenic poplar plants overexpressing gamma-glutamylcysteine synthetase towards chloroacetanilide herbicides. Journal of experimental botany 20010501
Adsorption of chloroacetanilide herbicides on soil (I). Structural influence of chloroacetanilide herbicide for their adsorption on soils and its components. Journal of environmental sciences (China) 20010101
Properties