Home Other Building Blocks 2-Aminofluorene

2-Aminofluorene

CAS No.:
153-78-6
Catalog Number:
AG003GJE
Molecular Formula:
C13H11N
Molecular Weight:
181.2331
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$44
- +
5g
98%
In Stock USA
United States
$88
- +
25g
98%
In Stock USA
United States
$271
- +
Product Description
Catalog Number:
AG003GJE
Chemical Name:
2-Aminofluorene
CAS Number:
153-78-6
Molecular Formula:
C13H11N
Molecular Weight:
181.2331
MDL Number:
MFCD08459291
IUPAC Name:
9H-fluoren-2-amine
InChI:
InChI=1S/C13H11N/c14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7,14H2
InChI Key:
CFRFHWQYWJMEJN-UHFFFAOYSA-N
SMILES:
Nc1ccc2c(c1)Cc1c2cccc1
EC Number:
205-817-8
UNII:
3A69OS195N
UN Number:
2811
Properties
Complexity:
213  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
181.089g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
181.238g/mol
Monoisotopic Mass:
181.089g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
26A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.1  
Literature
Title Journal
In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of γ-hydroxybutyrate (GHB) binding. Toxicology in vitro : an international journal published in association with BIBRA 20170401
Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites. Archives of toxicology 20151201
Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1. Chemical research in toxicology 20130617
Binary and ternary binding affinities between exonuclease-deficient Klenow fragment (Kf-exo(-)) and various arylamine DNA lesions characterized by surface plasmon resonance. Chemical research in toxicology 20120820
The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat. Experimental and molecular pathology 20120801
Protective effect of Enicostema axillare on mutagenicity of Salmonella typhimurium by increasing free radical scavenging abilities. Pharmaceutical biology 20120601
Synthesis, study on anti-arthritic, anti-inflammatory activity and toxicity of some novel bis-oxy cyclophane diamides. Bioorganic & medicinal chemistry letters 20120601
Roles of human sulfotransferases in genotoxicity of carcinogens using genetically engineered umu test strains. Environmental and molecular mutagenesis 20120301
Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic mice. PloS one 20120101
[The role of metabolic activation of promutagens in the genome destabilization under pheromonal stress in the house mouse (Mus musculus)]. Genetika 20111001
Carbon black nanoparticles impair acetylation of aromatic amine carcinogens through inactivation of arylamine N-acetyltransferase enzymes. ACS nano 20110628
Antimutagenic and antioxidant characteristics of Chukrasia tabularis A Juss extracts. International journal of toxicology 20110201
Pulmonary cytochrome P450 enzymes belonging to the CYP4B subfamily from an Australian marsupial, the tammar wallaby (Macropus eugenii). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110101
Incorporation of 3-aminobenzanthrone into 2'-deoxyoligonucleotides and its impact on duplex stability. Journal of nucleic acids 20110101
Broad spectrum antimutagenic activity of antioxidant active fraction of punica granatum L. peel extracts. Mutation research 20101221
Cadmium alters the biotransformation of carcinogenic aromatic amines by arylamine N-acetyltransferase xenobiotic-metabolizing enzymes: molecular, cellular, and in vivo studies. Environmental health perspectives 20101201
Antimutagenic potential of glucosinolate-rich seed extracts of broccoli (Brassica oleracea L var italica Plenck). International journal of toxicology 20101201
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Biosynthesis and characterization of organosoluble conjugated poly(2-aminofluorene) with the pyrazine bridged. Biomacromolecules 20101011
Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet). Chemico-biological interactions 20100805
Antioxidant and antimutagenic activity of Carum copticum fruit extracts. Toxicology in vitro : an international journal published in association with BIBRA 20100601
Nuclear factor-kappa B as a promising target for selenium chemoprevention in rat hepatocarcinogenesis. Journal of gastroenterology and hepatology 20100401
Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4. Nature structural & molecular biology 20100301
Enthalpy-entropy contribution to carcinogen-induced DNA conformational heterogeneity. Biochemistry 20100119
Effect of antisense oligomer in controlling c-raf.1 overexpression during diethylnitrosamine-induced hepatocarcinogenesis in rat. Cancer chemotherapy and pharmacology 20100101
Modulatory role of alizarin from Rubia cordifolia L. against genotoxicity of mutagens. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Mutagenicity of new lead compounds to treat sickle cell disease symptoms in a Salmonella/microsome assay. International journal of molecular sciences 20100101
Cellular proliferation, cell death, and liver histology in Gambusia affinis after dietary exposure to benzidine and 2-aminofluorene. International journal of toxicology 20100101
Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea. BMC complementary and alternative medicine 20100101
DNA polymerase: structural homology, conformational dynamics, and the effects of carcinogenic DNA adducts. Journal of nucleic acids 20100101
Anti- and pro-mutagenic effects of silymarin in the Ames bacterial reverse mutation assay. Phytotherapy research : PTR 20091001
Screening for reactive metabolites using electro-optical arrays featuring human liver cytosol and microsomal enzyme sources and DNA. Chemical communications (Cambridge, England) 20090928
Mutagenicity of aromatic amines and amides with chemical models for cytochrome P450 in Ames assay. Toxicology in vitro : an international journal published in association with BIBRA 20090901
Effect of N-2-acetylaminofluorene and 2-aminofluorene adducts on DNA binding and synthesis by yeast DNA polymerase eta. Biochemistry 20090519
Influence of water hydrogen bonding on the reactions of arylnitrenium ions with guanosine: hydrogen-bonding effects can favor reaction at the C8 site. The journal of physical chemistry. B 20090507
Kinetics of deoxy-CTP incorporation opposite a dG-C8-N-2-aminofluorene adduct by a high-fidelity DNA polymerase. Journal of molecular biology 20090306
A stable and sensitive testing system for potential carcinogens based on DNA damage-induced gene expression in human HepG2 cell. Toxicology in vitro : an international journal published in association with BIBRA 20090201
Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis. Journal of molecular histology 20090201
4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats. Toxicological sciences : an official journal of the Society of Toxicology 20090101
Mutagenicity of Chinese traditional medicine Semen Armeniacae amarum by two modified Ames tests. BMC complementary and alternative medicine 20090101
Genotoxicity revaluation of three commercial nitroheterocyclic drugs: nifurtimox, benznidazole, and metronidazole. Journal of parasitology research 20090101
Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole. Interdisciplinary toxicology 20081201
Possible relationship between the risk of Japanese bladder cancer cases and the CYP4B1 genotype. Japanese journal of clinical oncology 20080901
High-throughput approaches towards the definitive identification of pharmaceutical drug metabolites. 1. Evidence for an ortho effect on the fragmentation of 4-benzenesulfinyl-3-methylphenylamine using electrospray ionisation mass spectrometry. Rapid communications in mass spectrometry : RCM 20080801
Mutagenicity and antimutagenicity of teas used in popular medicine in the salmonella/microsome assay. Toxicology in vitro : an international journal published in association with BIBRA 20080601
Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1. Biochemical pharmacology 20080401
Electrochemical genotoxicity screening for arylamines bioactivated by N-acetyltransferase. Analytical chemistry 20080215
Fluorescence probing of aminofluorene-induced conformational heterogeneity in DNA duplexes. Chemical research in toxicology 20080201
Antigenotoxic effect of extract from Cynara cardunculus L. Phytotherapy research : PTR 20080101
Determination of genotoxic, antigenotoxic and cytotoxic potential of the extract from lichen Cetraria aculeata (Schreb.) Fr. in vitro. Phytotherapy research : PTR 20080101
Effects of luteolin on distribution and metabolism of 2-aminofluorene in male Sprague-Dawley rats. In vivo (Athens, Greece) 20080101
Modulation of energy metabolic enzyme expression in N-nitrosodiethylamine-mediated hepatocarcinogenesis by Chinese herbs, Huqi San. BioFactors (Oxford, England) 20080101
Solvent effects on intermolecular proton transfer: the rates of nitrene protonation and their correlation with Swain acity. Organic letters 20071206
The metabolic activation of 2-aminofluorine, 4-aminobiphenyl, and benzidine by cytochrome P-450-107S1 of Pseudomonas aeruginosa. Toxicology in vitro : an international journal published in association with BIBRA 20071201
Probing the sequence effects on NarI-induced -2 frameshift mutagenesis by dynamic 19F NMR, UV, and CD spectroscopy. Biochemistry 20071120
Time-resolved resonance Raman investigation of the 2-fluorenylnitrenium ion reactions with C8 guanosine derivatives. The journal of physical chemistry. B 20071108
Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells. Chemical research in toxicology 20071101
Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse. Drug metabolism and disposition: the biological fate of chemicals 20070701
The anti-mutagenic and antioxidant effects of bile pigments in the Ames Salmonella test. Mutation research 20070518
Time-resolved resonance Raman study of the reaction of the 2-fluorenylnitrenium ion with 2-fluorenylazide. The journal of physical chemistry. A 20070301
Conformation-specific recognition of carcinogen-DNA adduct in escherichia coli nucleotide excision repair. Chemical research in toxicology 20070101
Effects of oral administration of berberine on distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats. In vivo (Athens, Greece) 20070101
Suppression of T lymphocyte proliferation to antigenic and mitogenic stimuli by Benzo(alpha)pyrene and 2-aminofluorene metabolites. Immunopharmacology and immunotoxicology 20070101
Predicting drug metabolism-dependent toxicity for humans with a genetically engineered cell battery. Alternatives to laboratory animals : ATLA 20061201
Mutagenicity of cytochrome P450 2E1 substrates in the Ames test with the metabolic competent S. typhimurium strain YG7108pin3ERb5. Toxicology 20061110
In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice. Drug metabolism and disposition: the biological fate of chemicals 20061001
Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2. The Journal of pharmacology and experimental therapeutics 20061001
Stoichiometrically different inclusion complexes of 2-aminofluorene and 2-amino-9-hydroxyfluorene in beta-cyclodextrin: a spectrofluorimetric study. Journal of fluorescence 20060901
Induced circular dichroism characteristics as conformational probes for carcinogenic aminofluorene-DNA adducts. Chemical research in toxicology 20060801
Fluorimetric study on molecular recognition of beta-cyclodextrin with 2-amino-9-fluorenone. Journal of fluorescence 20060701
Microbial transformation of aniline derivatives: regioselective biotransformation and detoxification of 2-phenylenediamine by Bacillus cereus strain PDa-1. Journal of bioscience and bioengineering 20060701
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
A battery of in vivo and in vitro tests useful for genotoxic pollutant detection in surface waters. Aquatic toxicology (Amsterdam, Netherlands) 20060420
Metabolic activation of bladder procarcinogens, 2-aminofluorene, 4-aminobiphenyl, and benzidine by Pseudomonas aeruginosa and other human endogenous bacteria. Toxicology in vitro : an international journal published in association with BIBRA 20060401
Study on the mutagenicity and antimutagenicity of beta-ionone in the Salmonella/microsome assay. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060401
Solvent effects on the reactivity of fluorenyl nitrenium ion with DNA-like probes. Biophysical chemistry 20060201
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. PLoS biology 20060101
The role of Ca2+ in (-)-menthol-induced human promyelocytic leukemia HL-60 cell death. In vivo (Athens, Greece) 20060101
Ketoprofen-inhibited N-acetyltransferase activity and gene expression in human colon tumor cells. Anticancer research 20060101
Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2). Melanoma research 20051201
Heterologous co-expression of human cytochrome P450 1A2 and polymorphic forms of N-acetyltransferase 2 for studies on aromatic amines in V79 Chinese hamster cells. Alternatives to laboratory animals : ATLA 20051201
New fluorophores based on trifluorenylamine with very large intrinsic three-photon absorption cross sections. Organic letters 20051027
Berberine inhibits arylamine N-acetyltransferase activity and gene expression in Salmonella typhi. Current microbiology 20051001
Involvement of molybdenum hydroxylases in reductive metabolism of nitro polycyclic aromatic hydrocarbons in mammalian skin. Drug metabolism and disposition: the biological fate of chemicals 20050901
Evaluation of mutagenic and antimutagenic activities of alpha-bisabolol in the Salmonella/microsome assay. Mutation research 20050801
Oral administration of paclitaxel affects the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats. Phytomedicine : international journal of phytotherapy and phytopharmacology 20050801
Diallyl disulfide inhibits N-acetyltransferase activity and gene expression in human esophagus epidermoid carcinoma CE 81T/VGH cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050701
Time-resolved resonance Raman observation of the 2-fluorenylnitrenium ion reaction with guanosine to form a C8 intermediate. Journal of the American Chemical Society 20050615
Lack of evidence for metabolism of p-phenylenediamine by human hepatic cytochrome P450 enzymes. Toxicology 20050601
Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines. Mutagenesis 20050501
Incorporation of N2-deoxyguanosine metabolic adducts of 2-aminonaphthalene and 2-aminofluorene into oligomeric DNA. Chemical research in toxicology 20050301
Over-expression, purification, and characterization of recombinant human arylamine N-acetyltransferase 1. The protein journal 20050201
Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase. The Biochemical journal 20050115
Eukaryotic arylamine N-acetyltransferase. Investigation of substrate specificity by high-throughput screening. Biochemical pharmacology 20050115
Effects of ellagic acid by oral administration on distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats. In vivo (Athens, Greece) 20050101
Ellagic acid inhibits growth and arylamine N-acetyltransferase activity and gene expression in Staphylococcus aureus. In vivo (Athens, Greece) 20050101
N-acetyltransferase is involved in baicalein-induced N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells. In vivo (Athens, Greece) 20050101
Effects of aspirin on the in vitro and in vivo acetylation of 2-aminofluorene in Sprague-Dawley rats. In vivo (Athens, Greece) 20050101
Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells. Anticancer research 20050101
Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. In vivo (Athens, Greece) 20050101
Berberine decreased N-acetylation of 2-aminofluorene through inhibition of N-acetyltransferase gene expression in human leukemia HL-60 cells. Anticancer research 20050101
Effects of exposure to diesel exhaust particles (DEP) on pulmonary metabolic activation of mutagenic agents. Mutation research 20041212
Antimutagenicity of coriander (Coriandrum sativum) juice on the mutagenesis produced by plant metabolites of aromatic amines. Toxicology letters 20041102
Evidence for arylamine N-acetyltransferase activity in Klebsiella pneumoniae. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20040801
Formation and reduction of aryl and heterocyclic nitroso compounds and significance in the flux of hydroxylamines. Chemical research in toxicology 20040401
Mass spectrometric investigation of the mechanism of inactivation of hamster arylamine N-acetyltransferase 1 by N-hydroxy-2-acetylaminofluorene. Chemical research in toxicology 20040301
Inhibition of N-acetyltransferase activity and gene expression in human colon cancer cell lines by diallyl sulfide. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040201
Human acetyl CoA:arylamine N-acetyltransferase variants generated by random mutagenesis. Molecular pharmacology 20040101
The inhibition of N-acetyltransferase activity and gene expression in human bladder cancer cells (T24) by shikonin. In vivo (Athens, Greece) 20040101
PCR and flow cytometric analysis of paclitaxel-inhibited arylamine N-acetyltransferase activity and gene expression in human osteogenic sarcoma cells (U-2 OS). Anticancer research 20040101
N-acetyltransferase activity is involved in paclitaxel-induced N-acetylation of 2-aminofluorene in human bladder cancer cells (T24). Anticancer research 20040101
Shikonin inhibits the growth and N-acetylation of 2-aminofluorene in Helicobacter pylori from ulcer patients. Anticancer research 20040101
N-ethylphenyl acetamide (EPA) inhibits DNA synthesis and N-acetylation of 2-aminofluorene in human colon tumor cells (colo 205). Anticancer research 20040101
Paclitaxel inhibits N-acetyltransferase activity and gene expression in human stomach tumor cells (SC-M1). Research communications in molecular pathology and pharmacology 20040101
Gypenosides inhibited N-acetylation of 2-aminofluorene, N-acetyltransferase gene expression and DNA adduct formation in human cervix epithelioid carcinoma cells (HeLa). Research communications in molecular pathology and pharmacology 20040101
Effects of tamoxifen on DNA adduct formation and arylamines N-acetyltransferase activity in human breast cancer cells. Research communications in molecular pathology and pharmacology 20040101
Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease. Biochemistry 20031104
Arylamine N-acetyltransferases: covalent modification and inactivation of hamster NAT1 by bromoacetamido derivatives of aniline and 2-aminofluorene. Journal of protein chemistry 20031101
Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells. Leukemia research 20030901
Neonatal ontogeny of murine arylamine N-acetyltransferases: implications for arylamine genotoxicity. Toxicological sciences : an official journal of the Society of Toxicology 20030601
Curcumin inhibited the arylamines N-acetyltransferase activity, gene expression and DNA adduct formation in human lung cancer cells (A549). Toxicology in vitro : an international journal published in association with BIBRA 20030601
Paclitaxel (taxol) inhibits the arylamine N-acetyltransferase activity and gene expression (mRNA NAT1) and 2-aminofluorene-DNA adduct formation in human bladder carcinoma cells (T24 and TSGH 8301). Pharmacology & toxicology 20030601
Characterization of pulmonary CYP4B2, specific catalyst of methyl oxidation of 3-methylindole. Molecular pharmacology 20030501
Xanthine oxidase-catalyzed metabolism of 2-nitrofluorene, a carcinogenic air pollutant, in rat skin. Drug metabolism and disposition: the biological fate of chemicals 20030401
Time-resolved resonance Raman and density functional study of an azirine intermediate in the 2-fluorenylnitrene ring-expansion reaction to form a dehydroazepine product. Chemistry (Weinheim an der Bergstrasse, Germany) 20030317
Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster. Pharmacogenetics 20030301
Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay. Mutagenesis 20030301
Mutagenic and antimutagenic potential of the medicinal plants M. laevigata and C. xanthocarpa. Phytotherapy research : PTR 20030301
Studies on correlation of antimutagenic and antiproliferative activities of Juglans regia L. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101
Bioassay-guided isolation of antimutagenic factors from fruits of Terminalia bellerica. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101
Luteolin induces N-acetylation and DNA adduct of 2-aminofluorene accompanying N-acetyltransferase activity and gene expression in human bladder cancer T24 cell line. Anticancer research 20030101
Paclitaxel affects the amounts of the N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in Sprague-Dawley rats. In vivo (Athens, Greece) 20030101
N-acetyltransferase is involved in gypenosides-induced N-acetylation of 2-aminofluorene and DNA adduct formation in human cervix epidermoid carcinoma cells (Ca Ski). In vivo (Athens, Greece) 20030101
Curcumin decreases the DNA adduct formation, arylamines N-acetyltransferase activity and gene expression in human colon tumor cells (colo 205). In vivo (Athens, Greece) 20030101
Effects of (-)-menthol on the distribution and metabolism of 2-aminofluorene in various tissues of Sprague-Dawley rats. In vivo (Athens, Greece) 20030101
Deacylation of N-arylformamides and N-arylacetamides by formamidase in rat liver. Drug metabolism and disposition: the biological fate of chemicals 20021201
Antimutagenic effects of black tea (World Blend) and its two active polyphenols theaflavins and thearubigins in Salmonella assays. Phytotherapy research : PTR 20021101
Antimutagenic activities of acetone and methanol fractions of Terminalia arjuna. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001
Quercetin glucuronides inhibited 2-aminofluorene acetylation in human acute myeloid HL-60 leukemia cells. Phytomedicine : international journal of phytotherapy and phytopharmacology 20021001
Comments on the history and importance of aromatic and heterocyclic amines in public health. Mutation research 20020930
Metabolic oxidation of carcinogenic arylamines by p450 monooxygenases: theoretical support for the one-electron transfer mechanism. Mutation research 20020930
Berberine inhibited arylamine N-acetyltransferase activity and gene expression and DNA adduct formation in human malignant astrocytoma (G9T/VGH) and brain glioblastoma multiforms (GBM 8401) cells. Neurochemical research 20020901
Chemical models for cytochrome P450 as a biomimetic metabolic activation system in mutation assays. Mutation research 20020826
Functional genomics of C190T single nucleotide polymorphism in human N-acetyltransferase 2. Biological chemistry 20020601
Time-resolved resonance Raman spectroscopy and density functional study of 2-fluorenylnitrene and its dehydroazepine products. Chemistry (Weinheim an der Bergstrasse, Germany) 20020503
The effect of paclitaxel on 2-aminofluorene-DNA adducts formation and arylamine N-acetyltransferase activity and gene expression in human lung tumor cells (A549). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020501
The effect of paclitaxel on gene expression and activity of arylamine N-acetyltransferase and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020501
Transformation of mutagenic aromatic amines into non-mutagenic species by alkyl substituents. Part II: alkylation far away from the amino function. Mutation research 20020325
A correlative study on antimutagenic and chemopreventive activity of Acacia auriculiformis A. Cunn. and Acacia nilotica (L.) Willd. Ex Del. Drug and chemical toxicology 20020201
Effects of butylated hydroxyanisole and butylated hydroxytoluene on DNA adduct formation and arylamine N-acetyltransferase activity in human bladder tumour cells. Journal of applied toxicology : JAT 20020101
Antimutagenic and anticarcinogenic effects of Phyllanthus amarus. Phytomedicine : international journal of phytotherapy and phytopharmacology 20020101
Modulatory effect of phenolic fractions of Terminalia arjuna on the mutagenicity in Ames assay. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20020101
Preliminary evaluation of the cytotoxic and genotoxic potential of D-003: Mixture of very long chain fatty acids. Teratogenesis, carcinogenesis, and mutagenesis 20020101
Hydrocortisone affects the N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in Sprague-Dawley rats. Anticancer research 20020101
Induction of light emission by luminescent bacteria treated with UV light and chemical mutagens. Journal of applied genetics 20020101
Oral administration of 5-methoxypsoralen affects the distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats. In vivo (Athens, Greece) 20020101
Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in human promyelocytic leukemia cells. The American journal of Chinese medicine 20020101
Reversion mutation in dark variants of luminous bacteria and its application in gene toxicant monitoring. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101
Activities of cytochrome p450 enzymes in liver and kidney microsomes from systemic carnitine deficiency mice with a gene mutation of carnitine/organic cation transporter. Drug metabolism and pharmacokinetics 20020101
Metabolic activation of three arylamines and two organophosphorus insecticides by coriander (Coriandrum sativum) a common edible vegetable. Toxicology letters 20011215
Leukemia inhibitory factor decreases the arylamine N-acetyltransferase activity in human cumulus granulosa cells. Journal of assisted reproduction and genetics 20011201
Sulindac inhibited gene expression and activity of arylamine N-acetyltransferase and DNA-2-aminofluorene adduct formation in T24 human bladder tumor cells. Urological research 20011201
Transient-resonance Raman and density functional theory investigation of 4-biphenylylnitrenium, 2-fluorenylnitrenium, and diphenylnitrenium ions. Chemistry (Weinheim an der Bergstrasse, Germany) 20011119
Transformation of mutagenic aromatic amines into non-mutagenic species by alkyl substituents. Part I. Alkylation ortho to the amino function. Mutation research 20011115
Studies on the antimutagenesis of Phyllanthus orbicularis: mechanisms involved against aromatic amines. Mutation research 20011115
N-benzylimidazole for preparation of S9 fraction with multi-induction of metabolizing enzymes in short-term genotoxicity assays. Mutagenesis 20011101
S9 induction by the combined treatment with cyclohexanol and albendazole. Mutagenesis 20011101
Vitamin C inhibited DNA adduct formation and arylamine N-acetyltransferase activity and gene expression in rat glial tumor cells. Neurochemical research 20011001
Kinetics of acetyl coenzyme A: arylamine N-acetyltransferase from rapid and slow acetylator human benign prostatic hyperplasia tissues. Urological research 20011001
CYP1A2 is expressed along with CYP1A1 in the human lung. Cancer letters 20010928
Antimutagenicity and induction of anticarcinogenic phase II enzymes by basidiomycetes. Journal of ethnopharmacology 20010901
Kinetics of acetyl coenzyme A: arylamine N-acetyltransferase from human cumulus cells. Journal of assisted reproduction and genetics 20010901
Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010701
A transgenic mouse expressing human CYP4B1 in the liver. Biochemical and biophysical research communications 20010615
Inhibitory actions of luteolin on the growth and arylamine N-acetyltransferase activity in strains of Helicobacter pylori from ulcer patients. Toxicology in vitro : an international journal published in association with BIBRA 20010601
Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase. Mutation research 20010531
Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms. Pharmacogenetics 20010401
Transient resonance Raman and density functional theory investigation of the 2-fluorenylnitrenium ion. Journal of the American Chemical Society 20010321
CYP1A2 is expressed along with CYP1A1 in the human lung. Cancer letters 20010310
Antimutagenic potential of extracts isolated from Terminalia arjuna. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20010101
Ellagic acid inhibited 2-aminofluorene and p-aminobenzoic acid acetylation by mononuclear leucocytes from Sprague-Dawley rats. Cytobios 20010101
Luteolin inhibits the growth and arylamine N-acetyl-transferase activity in Neisseria gonorrhoeae. Microbios 20010101
Effect of norcantharidin on N-acetyltransferase activity in HepG2 cells. The American journal of Chinese medicine 20010101
Metabolism of 2-nitrofluorene, 2-aminofluorene and 2-acylaminofluorenes in rat and dog and the role of intestinal bacteria. Xenobiotica; the fate of foreign compounds in biological systems 20010101
Effects of carmustine on aminofluorene-DNA adducts formation in rat glial tumor cells. Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 20010101
Effects of (-)-menthol on arylamine N-acetyltransferase activity in human liver tumor cells. The American journal of Chinese medicine 20010101
Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons. Mutation research 20000323
Rhein affects arylamine N-acetyltransferase activity in Helicobacter pylori from peptic ulcer patients. Journal of applied toxicology : JAT 19980101
Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation. Mutation research 19970801
p53 protein expression by hepatocarcinogens in the rat liver and its potential role in mitoinhibition of normal hepatocytes as a mechanism of hepatic tumour promotion. Carcinogenesis 19970501
Function and localization of cytochromes P450 involved in the metabolic activation of food-derived heterocyclic amines. Princess Takamatsu symposia 19950101
Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test. Mutation research 19931201
Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002. Cancer research 19890615
N-hydroxy-2-acetylaminofluorene as effective inhibitor of aldehyde oxidase. Biochemical and biophysical research communications 19860716
Properties