Home Aminos (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS No.:
13441-51-5
Catalog Number:
AG003GDY
Molecular Formula:
C10H12N2O3
Molecular Weight:
208.2139
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Product Description
Catalog Number:
AG003GDY
Chemical Name:
(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
CAS Number:
13441-51-5
Molecular Formula:
C10H12N2O3
Molecular Weight:
208.2139
MDL Number:
MFCD00133224
IUPAC Name:
(2R)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
InChI:
InChI=1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m1/s1
InChI Key:
YGPSJZOEDVAXAB-MRVPVSSYSA-N
SMILES:
OC(=O)[C@@H](CC(=O)c1ccccc1N)N
UNII:
DK8PQD0WC5
Properties
Complexity:
255  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
208.085g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
208.217g/mol
Monoisotopic Mass:
208.085g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
106A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2.2  
Literature
Title Journal
Kynurenic acid and 3-hydroxykynurenine production from D-kynurenine in mice. Brain research 20120521
Enzymatic transamination of D-kynurenine generates kynurenic acid in rat and human brain. Journal of neurochemistry 20120301
Inhibition of D-amino acid oxidase activity by antipsychotic drugs evaluated by a fluorometric assay using D-kynurenine as substrate. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
Changes in the plasma concentrations of D-kynurenine and kynurenic acid in rats after intraperitoneal administration of tryptophan enantiomers. Chirality 20101101
Changes in extracellular kynurenic acid concentrations in rat prefrontal cortex after D-kynurenine infusion: an in vivo microdialysis study. Neurochemical research 20100401
Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B. Proceedings of the National Academy of Sciences of the United States of America 20090310
Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice. Molecular brain 20090101
3-[(3-Dehydroabietamidopropyl)dimethylammonio]-1-propane-sulfonate as a new type of chiral surfactant for enantiomer separation in micellar electrokinetic chromatography. Journal of chromatography. A 20070323
Purification and biochemical characterization of some of the properties of recombinant human kynureninase. European journal of biochemistry 20020401
Properties