Home Other Building Blocks Phenylethanolamine

Phenylethanolamine

CAS No.:
7568-93-6
Catalog Number:
AG003GCC
Molecular Formula:
C8H11NO
Molecular Weight:
137.1790
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
85%
In Stock USA
United States
$13
- +
5g
85%
In Stock USA
United States
$19
- +
25g
85%
In Stock USA
United States
$63
- +
100g
85%
In Stock USA
United States
$225
- +
Product Description
Catalog Number:
AG003GCC
Chemical Name:
Phenylethanolamine
CAS Number:
7568-93-6
Molecular Formula:
C8H11NO
Molecular Weight:
137.1790
MDL Number:
MFCD00008137
IUPAC Name:
2-amino-1-phenylethanol
InChI:
InChI=1S/C8H11NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2
InChI Key:
ULSIYEODSMZIPX-UHFFFAOYSA-N
SMILES:
NCC(c1ccccc1)O
EC Number:
231-469-1
Properties
Complexity:
89.3  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
137.084g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
137.182g/mol
Monoisotopic Mass:
137.084g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
46.2A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
0.1  
Literature
Title Journal
Determination of phenylethanolamine A in animal hair, tissues and feeds by reversed phase liquid chromatography tandem mass spectrometry with QuEChERS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120701
Activated plasma coagulation β-Factor XII-induced vasoconstriction in rats. Clinical science (London, England : 1979) 20120601
Study on the use of boromycin as a chiral selector in capillary electrophoresis. Journal of chromatography. A 20120511
Murine models and cell lines for the investigation of pheochromocytoma: applications for future therapies? Endocrine pathology 20120301
Alterations of blood brain barrier function in hyperammonemia: an overview. Neurotoxicity research 20120201
Role of peripheral versus spinal 5-HT(7) receptors in the modulation of pain undersensitizing conditions. European journal of pain (London, England) 20120101
Sympathetic and catecholaminergic alterations in sleep apnea with particular emphasis on children. Frontiers in neurology 20120101
An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors. PloS one 20120101
Differential effects of Mycobacterium bovis--derived polar and apolar lipid fractions on bovine innate immune cells. Veterinary research 20120101
1-(2-Hy-droxy-2-phenyl-eth-yl)-3-(4-meth-oxy-phen-yl)urea. Acta crystallographica. Section E, Structure reports online 20111001
Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature 20110714
Stereoselective conjugate addition reactions to phenylglycinol-derived, unsaturated oxazolopiperidone lactams. Chemistry (Weinheim an der Bergstrasse, Germany) 20110704
Highly stereoselective double (R)-phenylglycinol-induced cyclocondensation reactions of symmetric aryl bis(oxoacids). Organic & biomolecular chemistry 20110407
A colorimetric chiral sensor based on chiral crown ether for the recognition of the two enantiomers of primary amino alcohols and amines. Chirality 20110401
Enantioselective synthesis of alkaloids from phenylglycinol-derived lactams. Natural product communications 20110401
An (R)-specific N-methyltransferase involved in human morphine biosynthesis. Archives of biochemistry and biophysics 20110201
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. International journal of molecular sciences 20110101
Potent inhibition of Acid ceramidase by novel B-13 analogues. Journal of lipids 20110101
Secondary hypertension: A rare cause. Indian journal of endocrinology and metabolism 20110101
A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects. Oxidative medicine and cellular longevity 20110101
Hypertension and other morbidities with Cushing's syndrome associated with corticosteroids: a review. Integrated blood pressure control 20110101
Role of reactive oxygen species in the neural and hormonal regulation of the PNMT gene in PC12 cells. Oxidative medicine and cellular longevity 20110101
Comparison of chiral electrophoretic separation methods for phenethylamines and application on impurity analysis. Journal of pharmaceutical and biomedical analysis 20101215
The inhibitory effect of a novel cytotoxic somatostatin analogue AN-162 on experimental glioblastoma. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20101001
Ligands in PSI structures. Acta crystallographica. Section F, Structural biology and crystallization communications 20101001
Targeted cytotoxic somatostatin analog AN-162 inhibits growth of human colon carcinomas and increases sensitivity of doxorubicin resistant murine leukemia cells. Cancer letters 20100801
A medicinal chemist's guide to molecular interactions. Journal of medicinal chemistry 20100722
Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/experimental approach. Mammalian genome : official journal of the International Mammalian Genome Society 20100401
Synthesis and evaluation of novel phenylethanolamine derivatives containing acetanilides as potent and selective beta3-adrenergic receptor agonists. Chemical & pharmaceutical bulletin 20100401
Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay. BMC biochemistry 20100101
Cerebral net exchange of large neutral amino acids after lipopolysaccharide infusion in healthy humans. Critical care (London, England) 20100101
Does proteolysis explain glutamine release from the septic brain? Critical care (London, England) 20100101
Intelligent chiral sensing based on supramolecular and interfacial concepts. Sensors (Basel, Switzerland) 20100101
Inhibition of human non-small cell lung cancers with a targeted cytotoxic somatostatin analog, AN-162. Peptides 20090901
Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives. Marine drugs 20090901
Synthesis of highly enantioenriched chiral alpha-aminoorganotins via diastereoselective ring opening of chiral N-(arenesulfonyl) 2-tributylstannyloxazolidines. The Journal of organic chemistry 20090821
Preclinical evaluation of properties of a new targeted cytotoxic somatostatin analog, AN-162 (AEZS-124), and its effects on tumor growth inhibition. Anti-cancer drugs 20090801
Shape of biomolecules by free jet microwave spectroscopy: 2-amino-1-phenylethanol and 2-methylamino-1-phenylethanol. The journal of physical chemistry. A 20090709
[Studies on the chemical constituents of Epimedium brevicornum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090701
Straightforward stereoselective access to cyclic peptidomimetics. The Journal of organic chemistry 20090605
Enantioselective total synthesis of the indole alkaloid 16-episilicine. Chemical communications (Cambridge, England) 20090528
Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups. Journal of medicinal chemistry 20090423
Thermodynamic functions of molecular conformations of (2-fluoro-2-phenyl-1-ethyl)ammonium ion and (2-hydroxy-2-phenyl-1-ethyl)ammonium ion as models for protonated noradrenaline and adrenaline: first-principles computational study of conformations and thermodynamic functions for the noradrenaline and adrenaline models. The journal of physical chemistry. A 20090319
Synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid. Journal of fluorescence 20090101
Preparation and chiral recognition of a mono[6A-N-1-(2-hydroxy)-phenylethylimino-6A-deoxy]-beta-cyclodextrin HPLC stationary phase. Journal of chromatographic science 20081001
Neuropharmacology. Indian journal of pharmacology 20081001
An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines. The Journal of organic chemistry 20080905
Formal total synthesis of (+)-gephyrotoxin. The Journal of organic chemistry 20080815
Discovery of a novel series of benzoic acid derivatives as potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. 3. Phenylethanolaminotetraline (PEAT) skeleton containing biphenyl or biphenyl ether moiety. Journal of medicinal chemistry 20080814
Enantioseparation and impurity determination of the enantiomers of novel phenylethanolamine derivatives by high performance liquid chromatography on amylose stationary phase. Analytica chimica acta 20080310
Solvent control of optical resolution of 2-amino-1-phenylethanol using dehydroabietic acid. Organic & biomolecular chemistry 20080207
D-phenylglycinol-derived non-covalent factor Xa inhibitors: effect of non-peptidic S4 linkage elements on affinity and anticoagulant activity. Bioorganic & medicinal chemistry letters 20071101
Purification and characterization of 2-aminoacetophenone reductase of newly isolated Burkholderia sp. YT. Journal of bioscience and bioengineering 20071101
The effect of solvation on biomolecular conformation: 2-amino-1-phenylethanol. The journal of physical chemistry. B 20070823
Enantioselective synthesis of 3,3-disubstituted piperidine derivatives by enolate dialkylation of phenylglycinol-derived oxazolopiperidone lactams. The Journal of organic chemistry 20070608
Enantioseparation of phenylglycinol in chiral-modified zeolite HY: a molecular simulation study. Chirality 20070601
Infrared spectroscopy and structure of photochemically protonated biomolecules in the gas phase: a noradrenaline analogue, lysine and alanyl alanine. Physical chemistry chemical physics : PCCP 20070528
Syntheses and anti-cancer activities of 2-[1-(indol-3-yl-/pyrimidin-5-yl-/pyridine-2-yl-/quinolin-2-yl)-but-3-enylamino]-2-phenyl-ethanols. Bioorganic & medicinal chemistry 20070315
Chiral separation of amino-alcohols using extractant impregnated resins. Journal of chromatography. A 20070216
Blockade of catecholamine-induced growth by adrenergic and dopaminergic receptor antagonists in Escherichia coli O157:H7, Salmonella enterica and Yersinia enterocolitica. BMC microbiology 20070101
Recent advances in identification and characterization of beta-adrenoceptor agonists and antagonists. Current topics in medicinal chemistry 20070101
Transcriptional regulation of human eosinophil RNases by an evolutionary- conserved sequence motif in primate genome. BMC molecular biology 20070101
Structure-selective recognition by voltammetry: enantiomeric determination of amines using azophenolic crowns in aprotic solvent. Analytical chemistry 20061101
Dynamic kinetic resolution and desymmetrization processes: a straightforward methodology for the enantioselective synthesis of piperidines. Chemistry (Weinheim an der Bergstrasse, Germany) 20061016
Polymer-coated hollow fiber microextraction combined with on-column stacking in capillary electrophoresis. Journal of chromatography. A 20060922
Alkylation of phenylglycinol-derived oxazolopiperidone lactams. Enantioselective synthesis of beta-substituted piperidines. The Journal of organic chemistry 20060512
Quantum simulation of a hydrated noradrenaline analog with the torsional path integral method. The journal of physical chemistry. A 20060119
Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase. Journal of medicinal chemistry 20051117
Functionalized pyrrolidines inhibit alpha-mannosidase activity and growth of human glioblastoma and melanoma cells. Journal of medicinal chemistry 20050630
Indium-mediated asymmetric Barbier-type allylation of aldimines in alcoholic solvents: synthesis of optically active homoallylic amines. The Journal of organic chemistry 20050429
3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a potent and orally active antagonist of the human gonadotropin-releasing hormone receptor. Design, synthesis, and in vitro and in vivo characterization. Journal of medicinal chemistry 20050224
Comparison of the binding affinity of some newly synthesized phenylethanolamine and phenoxypropanolamine compounds at recombinant human beta- and alpha1-adrenoceptor subtypes. The Journal of pharmacy and pharmacology 20050101
Conjugate additions to phenylglycinol-derived unsaturated delta-lactams. Enantioselective synthesis of uleine alkaloids. The Journal of organic chemistry 20041210
Transformation of 2-aminoacetophenone to ( S) -2-amino-1-phenylethanol by Arthrobacter sulfureus. Biotechnology letters 20040801
Brain amino acid abnormalities in kidney disease and diabetes mellitus. Forensic science international 20040610
MMA/MPEOMA/VSA copolymer as a novel blood-compatible material: ex vivo platelet adhesion study. Journal of materials science. Materials in medicine 20040201
Highly enantioselective ruthenium-catalyzed reduction of ketones employing readily available Peptide ligands. Chemistry (Weinheim an der Bergstrasse, Germany) 20040105
Thermodynamically controlled synthesis of amide bonds catalyzed by highly organic solvent-resistant penicillin acylase derivatives. Biotechnology progress 20040101
Chiral bis(amino alcohol)oxalamide gelators-gelation properties and supramolecular organization: racemate versus pure enantiomer gelation. Chemistry (Weinheim an der Bergstrasse, Germany) 20031121
Fluorescence sensing of ammonium and organoammonium ions with tripodal oxazoline receptors. Organic letters 20030501
Absence of binding of targeted analogs of somatostatin carrying cytotoxic radicals or radionuclides to growth hormone secretagogue receptors on human myocardium. Life sciences 20030425
Combination of liquid-phase microextraction and on-column stacking for trace analysis of amino alcohols by capillary electrophoresis. Journal of chromatography. A 20021206
Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits. Neuropharmacology 20021101
Structure-activity relationship studies of phenoxypropanolamine derivatives for beta 3-adrenergic activity. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101
Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry 20020122
Tuning and enhancing enantioselective quenching of calixarene hosts by chiral guest amines. Analytical chemistry 20020101
The enigma of conditioned taste aversion learning: stimulus properties of 2-phenylethylamine derivatives. Physiological research 20020101
Unprecedented oxidation of a phenylglycinol-derived 2-pyridone: enantioselective synthesis of polyhydroxypiperidines. Organic letters 20011018
[Isolation and fermentation conditions of strains producing 1-phenyl-2-amino-ethanol alcohol dehydrogenase]. Wei sheng wu xue bao = Acta microbiologica Sinica 20011001
Enantioselective molecular sensing of aromatic amines using tetra-(S)-di-2-naphthylprolinol calix[4]arene. The Analyst 20010701
[Studies on asymmetric synthesis of R-phenylethanolamine by whole cells of Arachnia sp. P163]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20010701
Activity of N-(phenethyl)phenylethanolamines at beta(1) and beta(2) adrenoceptors: structural modifications can result in selectivity for either subtype. Pharmacology 20010201
Depression during methadone withdrawal: no role for beta-phenylethylamine. Drug and alcohol dependence 19840101
[Clonidine for the treatment of heroin withdrawal syndrome]. Wiener klinische Wochenschrift 19830826
Properties