Home Aminos 2,4,7-Triamino-6-Phenylpteridine

2,4,7-Triamino-6-Phenylpteridine

CAS No.:
396-01-0
Catalog Number:
AG003FOL
Molecular Formula:
C12H11N7
Molecular Weight:
253.2626
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%(HPLC)
In Stock USA
United States
$48
- +
5g
98%(HPLC)
In Stock USA
United States
$83
- +
10g
98%(HPLC)
In Stock USA
United States
$121
- +
25g
98%(HPLC)
In Stock USA
United States
$246
- +
100g
98%(HPLC)
In Stock USA
United States
$812
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Product Description
Catalog Number:
AG003FOL
Chemical Name:
2,4,7-Triamino-6-Phenylpteridine
CAS Number:
396-01-0
Molecular Formula:
C12H11N7
Molecular Weight:
253.2626
MDL Number:
MFCD00006708
IUPAC Name:
6-phenylpteridine-2,4,7-triamine
InChI:
InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)
InChI Key:
FNYLWPVRPXGIIP-UHFFFAOYSA-N
SMILES:
Nc1nc(N)c2c(n1)nc(c(n2)c1ccccc1)N
EC Number:
206-904-3
UNII:
WS821Z52LQ
Properties
Complexity:
307  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
253.108g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
253.269g/mol
Monoisotopic Mass:
253.108g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
130A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1  
Literature
Title Journal
Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study. Environmental health perspectives 20150501
Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. PloS one 20140101
Genomic biomarkers for cardiotoxicity in rats as a sensitive tool in preclinical studies. Journal of applied toxicology : JAT 20131001
Antihypertensive drugs and lip cancer in non-Hispanic whites. Archives of internal medicine 20120910
Garlic for the prevention of cardiovascular morbidity and mortality in hypertensive patients. The Cochrane database of systematic reviews 20120815
Use of diuretics and the risk of gouty arthritis: a systematic review. Seminars in arthritis and rheumatism 20120601
Use of a rhesus Plasmodium cynomolgi model to screen for anti-hypnozoite activity of pharmaceutical substances. The American journal of tropical medicine and hygiene 20120601
Amiloride off-target effect inhibits podocyte urokinase receptor expression and reduces proteinuria. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501
A co-module approach for elucidating drug-disease associations and revealing their molecular basis. Bioinformatics (Oxford, England) 20120401
Bioavailability study of triamterene and xipamide using urinary pharmacokinetic data following single oral dose of each drug or their combination. Journal of pharmaceutical and biomedical analysis 20120305
Antihypertensive Treatment in the Elderly and Very Elderly: Always 'the Lower, the Better?'. International journal of hypertension 20120101
Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis. BMC medicine 20120101
A comprehensive review of hypertension in pregnancy. Journal of pregnancy 20120101
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Long-term efficacy and tolerability of a fixed-dose combination of antihypertensive agents: an open-label surveillance study in China. Clinical drug investigation 20111101
The central mechanism underlying hypertension: a review of the roles of sodium ions, epithelial sodium channels, the renin-angiotensin-aldosterone system, oxidative stress and endogenous digitalis in the brain. Hypertension research : official journal of the Japanese Society of Hypertension 20111101
[Clinical strategies for prevention of drug-induced urinary calculi]. Clinical calcium 20111001
Mineralocorticoid hypertension. Indian journal of endocrinology and metabolism 20111001
Pediatric endocrine hypertension. Indian journal of endocrinology and metabolism 20111001
Mild hyperkalemia and low eGFR a tedious recipe for cardiac disaster in the elderly: an unusual reversible cause of syncope and heart block. Heart international 20110929
Aldosterone blockers (mineralocorticoid receptor antagonism) and potassium-sparing diuretics. Journal of clinical hypertension (Greenwich, Conn.) 20110901
Drug-induced photodermatitis in elderly nursing home residents. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20110801
Prevention of NSAID-associated gastroduodenal injury in healthy volunteers-a randomized, double-blind, multicenter study comparing DA-9601 with misoprostol. Journal of Korean medical science 20110801
Dynamics of a heparin-binding domain of VEGF(165) complexed with its inhibitor triamterene. Biochemistry 20110607
Simultaneous analysis of hydrochlorothiazide, triamterene and reserpine in rat plasma by high performance liquid chromatography and tandem solid-phase extraction. Journal of separation science 20110301
Design and characterization of a laminar flow-through dissolution apparatus: Comparison of hydrodynamic conditions to those of common dissolution techniques. Pharmaceutical development and technology 20110201
Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110201
Bioequivalence evaluation of a triamterene-hydrochlorothiazide generic product: a new bioequivalence index for fixed-dose combinations. Regulatory toxicology and pharmacology : RTP 20110201
Modelling, solubility and pK(a) of five sparingly soluble drugs. International journal of pharmaceutics 20110117
Role of the kidneys in resistant hypertension. International journal of hypertension 20110101
Sequential injection chromatography with a miniaturized multi-channel fiber optic detector for separation and quantification of propranolol and hydrochlorothiazide. Chemistry Central journal 20110101
Intracranial aneurysms: review of current treatment options and outcomes. Frontiers in neurology 20110101
Trimethoprim-sulfamethoxazole induced hyperkalaemia in elderly patients receiving spironolactone: nested case-control study. BMJ (Clinical research ed.) 20110101
Skeletal muscle na channel disorders. Frontiers in pharmacology 20110101
Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. Scientia pharmaceutica 20110101
Studying relationships between environment and malaria incidence in Camopi (French Guiana) through the objective selection of buffer-based landscape characterisations. International journal of health geographics 20110101
Anticholinergic drugs and their effects on delirium and mortality in the elderly. Dementia and geriatric cognitive disorders extra 20110101
Integrated control of hypertension by olmesartan medoxomil and hydrochlorothiazide and rationale for combination. Integrated blood pressure control 20110101
Treatment of primary aldosteronism. Best practice & research. Clinical endocrinology & metabolism 20101201
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
'Interactive technology assessment' and beyond: the field trial of genetically modified grapevines at INRA-Colmar. PLoS biology 20101101
Genetic analyses of the chimeric CYP11B1/CYP11B2 gene in a Korean family with glucocorticoid-remediable aldosteronism. Journal of Korean medical science 20100901
A novel screen using the Reck tumor suppressor gene promoter detects both conventional and metastasis-suppressing anticancer drugs. Oncotarget 20100801
Effectiveness of initiating treatment with valsartan/hydrochlorothiazide in patients with stage-1 or stage-2 hypertension. Journal of human hypertension 20100701
Continuous wavelet and derivative transform applied to the overlapping spectra for the quantitative spectrophotometric multi-resolution of triamterene and hydrochlorothiazide in triamterene-H tablets. Talanta 20100615
A practical approach to genetic hypokalemia. Electrolyte & blood pressure : E & BP 20100601
Light induced fluorescence for predicting API content in tablets: sampling and error. International journal of pharmaceutics 20100531
Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells: consideration of triamterene to treat lupus. Medical hypotheses 20100501
Drug attitude and adherence to anti-glaucoma medication. Yonsei medical journal 20100301
Spectrophotometric and spectrodensitometric determination of triamterene and xipamide in pure form and in pharmaceutical formulation. Drug testing and analysis 20100301
Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension. The Cochrane database of systematic reviews 20100120
Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases. Journal of medicinal chemistry 20100114
Resolving anaphoras for the extraction of drug-drug interactions in pharmacological documents. BMC bioinformatics 20100101
Combination therapy in hypertension: An update. Diabetology & metabolic syndrome 20100101
Gitelman syndrome with mental retardation: a case report. Journal of nephrology 20100101
Deoxycorticosterone producing tumor as a cause of resistant hypertension. Case reports in medicine 20100101
Pioglitazone and alogliptin combination therapy in type 2 diabetes: a pathophysiologically sound treatment. Vascular health and risk management 20100101
Pregabalin, the lidocaine plaster and duloxetine in patients with refractory neuropathic pain: a systematic review. BMC neurology 20100101
Pilot study: rapidly cycling hypobaric pressure improves pain after 5 days in adiposis dolorosa. Journal of pain research 20100101
New and improved strategies for the treatment of gout. International journal of nephrology and renovascular disease 20100101
Diuretic and natriuretic activity of two mistletoe species in rats. Pharmacognosy research 20100101
Risks associated with melamine and related triazine contamination of food. Emerging health threats journal 20100101
Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database. Toxicology 20091109
Identification of chemical compounds that induce HIF-1alpha activity. Toxicological sciences : an official journal of the Society of Toxicology 20091101
Heritable forms of hypertension. Pediatric nephrology (Berlin, Germany) 20091001
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening. Journal of medicinal chemistry 20090723
Consensus guidelines for oral dosing of primarily renally cleared medications in older adults. Journal of the American Geriatrics Society 20090201
Update on the treatment of ocular toxoplasmosis. International journal of medical sciences 20090101
Graz Endocrine Causes of Hypertension (GECOH) study: a diagnostic accuracy study of aldosterone to active renin ratio in screening for primary aldosteronism. BMC endocrine disorders 20090101
[Asynchronous lumbar synovial cysts after surgical resection: a case report]. Zeitschrift fur Orthopadie und Unfallchirurgie 20090101
Responses to diuretic treatment in gene-targeted mice lacking serum- and glucocorticoid-inducible kinase 1. Kidney & blood pressure research 20090101
[Simultaneous determination of 8 illegal synthetic drugs in antihypertensive dietary supplements by high performance liquid chromatography-mass spectrometry]. Se pu = Chinese journal of chromatography 20090101
Can tomato juice be used for prophylaxis in recurrent stone formers? Indian journal of urology : IJU : journal of the Urological Society of India 20090101
Renin-angiotensin-aldosterone system in the elderly: rational use of aliskiren in managing hypertension. Clinical interventions in aging 20090101
A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients with heart disease. Cardiovascular diabetology 20090101
Potential prescription patterns and errors in elderly adult patients attending public primary health care centers in Mexico City. Clinical interventions in aging 20090101
Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue. PloS one 20090101
A high throughput assay to identify small molecule modulators of prostatic acid phosphatase. Current chemical genomics 20090101
Clinical approach in treatment of resistant hypertension. Integrated blood pressure control 20090101
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry 20081113
Determination of diuretics in human urine by hollow fiber-based liquid-liquid-liquid microextraction coupled to high performance liquid chromatography. The Analyst 20080901
Development of a vessel-simulating flow-through cell method for the in vitro evaluation of release and distribution from drug-eluting stents. Journal of controlled release : official journal of the Controlled Release Society 20080825
Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes. Molecular microbiology 20080701
Quantitative investigation of the role of breast cancer resistance protein (Bcrp/Abcg2) in limiting brain and testis penetration of xenobiotic compounds. Drug metabolism and disposition: the biological fate of chemicals 20080601
Kinase-likeness and kinase-privileged fragments: toward virtual polypharmacology. Journal of medicinal chemistry 20080313
Drug-induced crystal nephropathy: an update. Expert opinion on drug safety 20080301
How long does it take to coil an intracranial aneurysm? Neuroradiology 20080101
Evaluation of a neck-bridge device to assist endovascular treatment of wide-neck aneurysms of the anterior circulation. AJNR. American journal of neuroradiology 20080101
Acute bilateral simultaneous angle closure glaucoma after topiramate administration: a case report. Journal of medical case reports 20080101
Practical aspects in the management of hypokalemic periodic paralysis. Journal of translational medicine 20080101
Simultaneous determination of triamterene and hydrochlorothiazide in tablets using derivative spectrophotometry. Acta poloniae pharmaceutica 20080101
The prince and the pauper. A tale of anticancer targeted agents. Molecular cancer 20080101
Determination of losartan and triamterene in pharmaceutical compounds and urine using cathodic adsorptive stripping voltammetry. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080101
Validated HPTLC Method for Simultaneous Determination of Quinapril Hydrochloride and Hydrochlorothiazide in a Tablet Dosage Form. Indian journal of pharmaceutical sciences 20080101
Determination of norfloxacin in rat liver perfusate using capillary electrophoresis with laser-induced fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070901
A study of western pharmaceuticals contained within samples of Chinese herbal/patent medicines collected from New York City's Chinatown. Legal medicine (Tokyo, Japan) 20070901
Fast quantitative determination of diuretic drugs in tablets and human urine by microchip electrophoresis with native fluorescence detection. Electrophoresis 20070801
Stereoselective syntheses of the 2-Isopropenyl-2,3-dihydrobenzofuran nucleus: potential chiral building blocks for the syntheses of tremetone, hydroxytremetone, and rotenone. The Journal of organic chemistry 20070413
Periprocedural morbidity and mortality by endovascular treatment of cerebral aneurysms with GDC: a retrospective 12-year experience of a single center. Neurosurgical review 20070401
Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis. Arthritis research & therapy 20070101
[Influence of diuretics on occupationally important qualities of engine drivers]. Meditsina truda i promyshlennaia ekologiia 20070101
Update of diuretics in the treatment of hypertension. American journal of therapeutics 20070101
Naturalised Vitis rootstocks in Europe and consequences to native wild grapevine. PloS one 20070101
Fast gas chromatographic/mass spectrometric determination of diuretics and masking agents in human urine: Development and validation of a productive screening protocol for antidoping analysis. Journal of chromatography. A 20061201
High-speed gas chromatography in doping control: fast-GC and fast-GC/MS determination of beta-adrenoceptor ligands and diuretics. Journal of separation science 20061201
Potassium-sparing diuretics. Nursing times 20060701
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
[Drug-induced renal calculi]. Annales d'urologie 20060401
[Liddle syndrome: Pathogenesis, pathophysiology, and therapy]. Nihon rinsho. Japanese journal of clinical medicine 20060201
[Diuretic therapy in heart failure]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20060101
Design, synthesis and diuretic activity of some novel 2,4-diamino-6-aryl-7-arylaminopyrimido [4,5-d]pyrimidin-5(6H)-ones. Arzneimittel-Forschung 20060101
A comparison of theoretical methods of calculation of partition coefficients for selected drugs. Acta poloniae pharmaceutica 20060101
Multicommuted flow-through fluorescence optosensor for determination of furosemide and triamterene. Analytical and bioanalytical chemistry 20051101
Drug-induced megaloblastic anemia. Digestive diseases and sciences 20051001
[Differential diagnosis of a macrocytic, hyperchromic anemia following alcohol abuse and simultaneous therapy with triamterene and cotrimoxazole]. Deutsche medizinische Wochenschrift (1946) 20050923
Hydrochlorothiazide-induced noncardiogenic pulmonary edema: an underrecognized yet serious adverse drug reaction. Pharmacotherapy 20050901
Differing effects of mineralocorticoid receptor-dependent and -independent potassium-sparing diuretics on fibrinolytic balance. Hypertension (Dallas, Tex. : 1979) 20050801
Rate-limiting biotransformation of triamterene is mediated by CYP1A2. International journal of clinical pharmacology and therapeutics 20050701
[A case of Gitelman's syndrome presenting with severe hypocalcaemia and hypokalemic periodic paralysis]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20050701
Polymeric worm micelles as nano-carriers for drug delivery. Nanotechnology 20050701
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Capillary electrophoretic determination of triamterene, methotrexate, and creatinine in human urine. Journal of separation science 20050501
Attenuation of the kaluretic properties of furosemide by triamterene (Dyrenium) in healthy volunteers. International journal of clinical pharmacology and therapeutics 20050201
[Capillary electrophoresis with end-column electrochemical detection for hydrochlorothiazide and triamterene diuretics]. Se pu = Chinese journal of chromatography 20050101
Dermatological conditions during TNF-alpha-blocking therapy in patients with rheumatoid arthritis: a prospective study. Arthritis research & therapy 20050101
Procedures for restoring vestibular disorders. GMS current topics in otorhinolaryngology, head and neck surgery 20050101
[Determination of five components in compound hypotensive tablet by HPLC]. Yao xue xue bao = Acta pharmaceutica Sinica 20040801
The G-tolerance after pharmacological hypohydration. Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology 20040701
Coil treatment of a fusiform upper basilar trunk aneurysm with a combination of 'kissing' neuroform stents, TriSpan-, 3D- and fibered coils, and permanent implantation of the microguidewires. Neuroradiology 20040601
Transvenous coil treatment of a type a carotid cavernous fistula in association with transarterial trispan coil protection. AJNR. American journal of neuroradiology 20040401
Triamterene-beta-cyclodextrin systems: preparation, characterization and in vivo evaluation. AAPS PharmSciTech 20040301
Application of PLS regression to fluorimetric data for the determination of furosemide and triamterene in pharmaceutical preparations and triamterene in urine. Talanta 20040206
Effects of pH and the presence of micelles on the resolution of diuretics by reversed-phase liquid chromatography. Journal of chromatography. A 20040102
Treatment of congenital nephrogenic diabetes insipidus with hydrochlorothiazide and amiloride in an adult patient. Hormone research 20040101
Application of a fluorescence sensor for miniscale on-line monitoring of powder mixing kinetics. Journal of pharmaceutical sciences 20040101
Drug-induced renal calculi: epidemiology, prevention and management. Drugs 20040101
[Circadian rhythm of the renin-angiotensin-aldosterone system: a summary of our research studies]. La Clinica terapeutica 20040101
Use of the TriSpan coil to facilitate the transcatheter occlusion of pulmonary arteriovenous malformation. Cardiovascular and interventional radiology 20040101
Direct determination of triamterene by potentiometry using a coated wire selective electrode. Journal of pharmaceutical and biomedical analysis 20031204
Rational diuretic management in congestive heart failure: a case-based review. Critical care nursing clinics of North America 20031201
Endovascular treatment of a wide-neck renal artery bifurcation aneurysm. Journal of vascular and interventional radiology : JVIR 20031101
Identification and prediction of promiscuous aggregating inhibitors among known drugs. Journal of medicinal chemistry 20031009
Mutations in the epithelial Na+ channel ENaC outer pore disrupt amiloride block by increasing its dissociation rate. Molecular pharmacology 20031001
Photostability studies on the furosemide-triamterene drug association. Farmaco (Societa chimica italiana : 1989) 20030901
Pharmacological characterization of unique prazosin-binding sites in human kidney. Naunyn-Schmiedeberg's archives of pharmacology 20030701
Kinetic modeling of triamterene intestinal absorption and its inhibition by folic acid and methotrexate. Journal of drug targeting 20030501
Drug-induced myopia. Prescrire international 20030201
Restoration of arterial baroreflex function contributes to organ protection in spontaneously hypertensive rats treated with long-term hydrochlorothiazide mixture. Clinical and experimental pharmacology & physiology 20030101
Potentially significant drug interactions of class III antiarrhythmic drugs. Drug safety 20030101
Drug-induced urinary calculi. Reviews in urology 20030101
Liddle's syndrome associated with a point mutation in the extracellular domain of the epithelial sodium channel gamma subunit. Journal of hypertension 20021201
Screening for 18 diuretics and probenecid in doping analysis by liquid chromatography-tandem mass spectrometry. Biomedical chromatography : BMC 20021201
Thiazide-induced lichenoid photosensitivity. Clinical and experimental dermatology 20021101
Acetazolamide-induced muscle weakness in hypokalemic periodic paralysis. Internal medicine (Tokyo, Japan) 20020901
Use of the trispan device to assist coil embolization of high-flow arteriovenous fistulas. AJNR. American journal of neuroradiology 20020801
Non-traumatic neurological emergencies: emergency neuroradiological interventions. European radiology 20020701
Micellar electrokinetic capillary chromatography analysis of diuretics in pharmaceutical formulations. Talanta 20020516
Determination of triamterene by transitory retention in a continuous flow solid phase system with fluorimetric transduction. Journal of pharmaceutical and biomedical analysis 20020515
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Effects of anion and cation inhibitors and carbonic anhydrase inhibitors upon the activity of the gypsy moth (Lepidoptera: Lymantriidae) nucleo-polyhedrovirus. Journal of economic entomology 20020401
[Simultaneous analysis of four diuretic drugs by HPLC and its application to health food supplements advertising weight reduction]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20020401
Determination of triamterene and its main metabolite hydroxytriamterene sulfate in human urine by capillary electrophoresis using ultraviolet absorbance and laser-induced fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020325
Determination of triamterene and leucovorin in biological fluids by UV derivative-spectrophotometry and partial least-squares (PLS-1) calibration. Journal of pharmaceutical and biomedical analysis 20020101
[Liddle's syndrome: late diagnosis of a rare cause of arterial hypertension]. Jornal de pediatria 20020101
Structure-based generation of a new class of potent Cdk4 inhibitors: new de novo design strategy and library design. Journal of medicinal chemistry 20011220
Neck-bridge device for endovascular treatment of wide-neck bifurcation aneurysms: initial experience. Radiology 20011101
Are certain diuretics also anticonvulsants? Annals of neurology 20011001
Spectrophotometric simultaneous determination of triamterene and hydrochlorothiazide in triamterene-H tablets by multivariate calibration methods. Journal of pharmaceutical and biomedical analysis 20010901
Prolonged exercise following diuretic-induced hypohydration effects on fluid and electrolyte hormones. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010901
A family with liddle's syndrome caused by a mutation in the beta subunit of the epithelial sodium channel. Clinical and experimental hypertension (New York, N.Y. : 1993) 20010801
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry 20010719
The influence of age on the pharmacokinetics and pharmacodynamics of bemetizide and triamterene: a single and multiple dose study. Archives of gerontology and geriatrics 20010601
Disappearance of spironolactone-induced gynecomastia with triamteren. Internal medicine (Tokyo, Japan) 20010601
Neural tube defects in relation to use of folic acid antagonists during pregnancy. American journal of epidemiology 20010515
Simultaneous direct determination of amiloride and triamterene in urine using isopotential fluorometry. Analytical biochemistry 20010501
Antihypertensive drug prescription trends at the primary health care centres in Bahrain. Pharmacoepidemiology and drug safety 20010501
Folic acid antagonists during pregnancy and risk of birth defects. The New England journal of medicine 20010322
Evaluation of the TriSpan neck bridge device for the treatment of wide-necked aneurysms: an experimental study in canines. Stroke 20010201
Effects of the serine/threonine kinase SGK1 on the epithelial Na(+) channel (ENaC) and CFTR: implications for cystic fibrosis. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20010101
[Periodic paralysis secondary to urinary or gastrointestinal potassium loss]. Ryoikibetsu shokogun shirizu 20010101
Rational therapy of chronic venous insufficiency--chances and limits of the therapeutic use of horse-chestnut seeds extract. BMC cardiovascular disorders 20010101
In vitro antioxidant and photo-oxidant properties of dipyridamole. International journal of toxicology 20010101
Determination of hydrochlorothiazide, triamterene and propranolol hydrochloride by the spectrophotometric method and high-performance liquid chromatography (HPLC). Acta poloniae pharmaceutica 20010101
[Urinary lithiasis of medical origin]. Therapie 20010101
Nephrogenic diabetes insipidus persisting 57 months after cessation of lithium carbonate therapy: report of a case and review of the literature. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20000101
Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, and triamterene. Journal of the American Society of Nephrology : JASN 19950601
Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature 19940203
Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase. Antimicrobial agents and chemotherapy 19930901
Megaloblastic anaemia in an elderly patient treated with triamterene. The Netherlands journal of medicine 19910601
Irreversible renal failure associated with triamterene. American journal of nephrology 19910101
Triamterene nephrolithiasis: renewed attention is warranted. The Journal of urology 19901201
Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy. Protection by conventional doses of spironolactone but not triamterene. Chest 19901001
[Urinary lithiasis due to triamterene]. Annales d'urologie 19900101
Potassium restoration in hypertensive patients made hypokalemic by hydrochlorothiazide. Archives of internal medicine 19891201
Incidence of cardiac arrhythmias associated with mild hypokalemia induced by low-dose diuretic therapy for hypertension. Southern medical journal 19890801
Triamterene nephrolithiasis. Military medicine 19890301
Maintenance of potassium balance during long-term diuretic therapy in chronic heart failure patients with thiazide-induced hypokalemia: comparison of potassium supplementation with potassium chloride and potassium-sparing agents, amiloride and triamterene. International journal of clinical pharmacology, therapy, and toxicology 19880501
[13 cases of drug-induced calculi]. Annales d'urologie 19880101
Angiotensin converting enzyme inhibitors and diuretics. British medical journal (Clinical research ed.) 19871121
Triamterene bladder calculus. Urology 19870801
Indomethacin and ibuprofen-induced reversible acute renal failure in a patient with systemic lupus erythematosus. The Netherlands journal of medicine 19870401
Dyazide-induced reversible acute renal failure associated with intracellular crystal deposition. American journal of kidney diseases : the official journal of the National Kidney Foundation 19861201
[Nephrogenic diabetes insipidus associated with triamterene-cyclothiazide]. Presse medicale (Paris, France : 1983) 19861108
Acute renal failure and hyperkalemia associated with triamterene and indomethacin. Veterinary and human toxicology 19860601
Triamterene stones and computerized axial tomography. Urology 19860201
Metabolic fate and solubility of triamterene--not an explanation for triamterene nephrolithiasis. Journal of pharmaceutical sciences 19860201
[Effect of diuretics on the course of experimental arrhythmias]. Farmakologiia i toksikologiia 19860101
[Nephrolithiasis caused by triamterene. Presentation of 2 cases]. Actas urologicas espanolas 19860101
The true composition of kidney stones passed during triamterene therapy. The Journal of urology 19851101
Renal failure with potassium-sparing diuretics. The New Zealand medical journal 19850814
Effects of triamterene and amiloride on urinary sediment in hypertensive patients taking hydrochlorothiazide. Lancet (London, England) 19850713
Triamterene calculus. The Journal of urology 19850601
Anuric renal failure precipitated by indomethacin and triamterene. Nephron 19850101
Early changes in plasma and urinary potassium in diuretic-treated patients with systemic hypertension. The American journal of cardiology 19841101
Propranolol in the treatment of cirrhotic ascites. Archives of internal medicine 19840901
[Nephrolithiasis caused by triamterene]. Revista clinica espanola 19840801
Relationship of renal prostaglandins to three diuretics. Prostaglandins, leukotrienes, and medicine 19840601
The short-term effects of reducing elevated blood pressure in elderly patients with propranolol and dyazide. Age and ageing 19840301
Diuretic-induced hypokalemia in uncomplicated systemic hypertension: effect of plasma potassium correction on cardiac arrhythmias. The American journal of cardiology 19831101
Thiazide-induced hyponatremia. Southern medical journal 19831101
Amantadine-dyazide interaction. Canadian Medical Association journal 19831101
[Detection and diagnosis of drug induced lithiasis]. Annales de biologie clinique 19830101
Drug-induced acute interstitial nephritis with granulomas. Human pathology 19830101
Pharmacokinetics of triamterene after i.v. administration to man: determination of bioavailability. European journal of clinical pharmacology 19830101
Risk of kidney stones. JAMA 19821022
Lithium intoxication and its clinical management. Southern medical journal 19820601
[Acute kidney failure caused by triamterene and hydrochlorothiazide]. Deutsche medizinische Wochenschrift (1946) 19820528
Diuretic induced hypokalemia in the elderly. The Journal of family practice 19820401
Reversible acute renal failure from combined triamterene and indomethacin: a study in healthy subjects. Annals of internal medicine 19820301
Triamterene-induced acute interstitial nephritis. Lancet (London, England) 19820123
[Triamterene induced nephrolithiasis (author's transl)]. Journal d'urologie 19820101
[Triamterene and renal calculi]. Nephrologie 19820101
Hypokalemic periodic paralysis exacerbated by acetazolamide. Neurology 19811101
Nephrogenic diabetes insipidus associated with Dyazide (triamterene-hydrochlorothiazide). British medical journal (Clinical research ed.) 19811031
Triamterene nephrolithiasis complicating dyazide therapy. The Journal of urology 19810801
Triamterene-induced nephrolithiasis. JAMA 19810626
Triamterene urolithiasis. Canadian Medical Association journal 19810615
Acute interstitial nephritis associated with thiazide diuretics. Clinical and pathologic observations in three cases. The American journal of medicine 19801201
Triamterene nephrolithiasis. JAMA 19801128
Triamterene-induced nephrolithiasis. Annals of internal medicine 19800301
[Drug induced nephrolithiasis: observation of an oxalate and hydroxylated triamterene stone (author's transl)]. Nephrologie 19800101
Triamterene-induced nephrolithiasis. Annals of internal medicine 19791101
Triamterene-induced immune haemolytic anaemia with acute intravascular haemolysis and acute renal failure. Scandinavian journal of haematology 19790801
[Triamterene-induced immune hemolytic anemia with acute intravascular hemolysis and acute renal failure (author's transl)]. [Rinsho ketsueki] The Japanese journal of clinical hematology 19790801
[Severe megaloblastic anaemia by triamterene in a patient with alcoholic liver cirrhosis (author's transl)]. Deutsche medizinische Wochenschrift (1946) 19790601
Maintenance of potassium balance during diuretic therapy. Acta medica Scandinavica 19790101
Antiarrhythmic activity of four pteridine compounds in ouabain intoxication. Clinical pharmacology and therapeutics 19750201
Diuretic-induced renal colic. JAMA 19730820
Mechanism of triamterene-induced megaloblastosis. Annals of internal medicine 19700901
Digitoxin induced cardiac necrosis and its inhibition. Cardiologia 19690101
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