Home Other Building Blocks 2',4',6'-Trihydroxyacetophenone

2',4',6'-Trihydroxyacetophenone

CAS No.:
480-66-0
Catalog Number:
AG003FN6
Molecular Formula:
C8H8O4
Molecular Weight:
168.1467
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$17
- +
25g
98%
In Stock USA
United States
$44
- +
100g
98%
In Stock USA
United States
$144
- +
500g
98%
In Stock USA
United States
$600
- +
Product Description
Catalog Number:
AG003FN6
Chemical Name:
2',4',6'-Trihydroxyacetophenone
CAS Number:
480-66-0
Molecular Formula:
C8H8O4
Molecular Weight:
168.1467
MDL Number:
MFCD00149091
IUPAC Name:
1-(2,4,6-trihydroxyphenyl)ethanone
InChI:
InChI=1S/C8H8O4/c1-4(9)8-6(11)2-5(10)3-7(8)12/h2-3,10-12H,1H3
InChI Key:
XLEYFDVVXLMULC-UHFFFAOYSA-N
SMILES:
CC(=O)c1c(O)cc(cc1O)O
EC Number:
207-556-5
UNII:
8L7XD8830T
NSC Number:
54927
Properties
Complexity:
168  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
168.042g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
168.148g/mol
Monoisotopic Mass:
168.042g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
77.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.1  
Literature
Title Journal
Synthesis and antimicrobial activity of geranyloxy- and farnesyloxy-acetophenone derivatives against oral pathogens. Fitoterapia 20120901
Analysis of initial reactions of MALDI based on chemical properties of matrixes and excitation condition. The journal of physical chemistry. B 20120816
Production and fragmentation of negative ions from neutral N-linked carbohydrates ionized by matrix-assisted laser desorption/ionization. Rapid communications in mass spectrometry : RCM 20120227
Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition. Analytical chemistry 20120221
Geranyl derivative of phloroacetophenone induces cancer cell-specific apoptosis through Bax-mediated mitochondrial pathway in MCF-7 human breast cancer cells. Biological & pharmaceutical bulletin 20120101
Molecular and catalytic properties of monoacetylphloroglucinol acetyltransferase from Pseudomonas sp. YGJ3. Bioscience, biotechnology, and biochemistry 20120101
Matrix-assisted laser desorption ionization mass spectrometry of maltohexaose and acetylsalicylic acid using alkali metal cation-substituted zeolites. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101
Plume expansion dynamics of matrix-assisted laser desorption ionization. Chemistry, an Asian journal 20111104
The 2',4',6'-trihydroxyacetophenone isolated from Myrcia multiflora has antiobesity and mixed hypolipidemic effects with the reduction of lipid intestinal absorption. Planta medica 20110901
Growth inhibitory activities of oxyprenylated and non-prenylated naturally occurring phenylpropanoids in cancer cell lines. Bioorganic & medicinal chemistry letters 20110715
Phloroglucinol mediates cross-talk between the pyoluteorin and 2,4-diacetylphloroglucinol biosynthetic pathways in Pseudomonas fluorescens Pf-5. Molecular microbiology 20110701
Structure of dihydrochalcones and related derivatives and their scavenging and antioxidant activity against oxygen and nitrogen radical species. Molecules (Basel, Switzerland) 20110221
EJMS protocol: systematic studies on TiO2-based phosphopeptide enrichment procedures upon in-solution and in-gel digestions of proteins. Are there readily applicable protocols suitable for matrix-assisted laser desorption/ionization mass spectrometry-based phosphopeptide stability estimations? European journal of mass spectrometry (Chichester, England) 20110101
Solid-phase thermodynamic interpretation of ion desorption in matrix-assisted laser desorption/ionization. The journal of physical chemistry. B 20101104
Synthesis of kaempferol 3-O-(3'',6''-di-O-E-p-coumaroyl)-β-D-glucopyranoside, efficient glycosylation of flavonol 3-OH with glycosyl o-alkynylbenzoates as donors. The Journal of organic chemistry 20101015
Synthesis of vicenin-1 and 3, 6,8- and 8,6-di-C-beta-D-(glucopyranosyl-xylopyranosyl)-4',5,7-trihydroxyflavones using two direct C-glycosylations of naringenin and phloroacetophenone with unprotected D-glucose and D-xylose in aqueous solution as the key reactions. Carbohydrate research 20100903
Prenylflavonoids and prenyl/alkyl-phloroacetophenones: synthesis and antitumour biological evaluation. European journal of medicinal chemistry 20100901
Crystal structure and computational analyses provide insights into the catalytic mechanism of 2,4-diacetylphloroglucinol hydrolase PhlG from Pseudomonas fluorescens. The Journal of biological chemistry 20100212
Use of a novel ionic liquid matrix for MALDI-MS analysis of glycopeptides and glycans out of total tryptic digests. Journal of mass spectrometry : JMS 20091101
Alkali-hydroxide-doped matrices for structural characterization of neutral underivatized oligosaccharides by MALDI time-of-flight mass spectrometry. Journal of mass spectrometry : JMS 20090301
The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2,5-dihydroxybenzoic acid, 2,4,6-trihydroxyacetophenone, alpha-cyano-4-hydroxycinnamic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane. Journal of mass spectrometry : JMS 20090201
Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors. Bioorganic & medicinal chemistry letters 20090201
Molecular modeling and inhibition of phospholipase A2 by polyhydroxy phenolic compounds. European journal of medicinal chemistry 20090101
Simultaneous analysis of vitamins and caffeine in energy drinks by surfactant-mediated matrix-assisted laser desorption/ionization. Analytical and bioanalytical chemistry 20080801
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of oligonucleotides. Current protocols in nucleic acid chemistry 20080601
Rapid screening of anthocyanins in berry samples by surfactant-mediated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid communications in mass spectrometry : RCM 20080101
Ion-induced nucleation in solution: promotion of solute nucleation in charged levitated droplets. Journal of the American Chemical Society 20070919
Strategies for the analysis of poly(methacrylic acid) by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Journal of the American Society for Mass Spectrometry 20070801
Suppression and enhancement of secondary ion formation due to the chemical environment in static-secondary ion mass spectrometry. Journal of the American Society for Mass Spectrometry 20070801
Phloracetophenone-induced choleresis in rats is mediated through Mrp2. American journal of physiology. Gastrointestinal and liver physiology 20070701
Polyketide folding in higher plants: biosynthesis of the phenylanthraquinone knipholone. The Journal of organic chemistry 20070427
Analysis of lipids using 2,4,6-trihydroxyacetophenone as a matrix for MALDI mass spectrometry. Analytical chemistry 20070415
Combined use of 2,4,6-trihydroxyacetophenone as matrix and enzymatic deglycosylation in organic-aqueous solvent systems for the simultaneous characterization of complex glycoproteins and N-glycans by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid communications in mass spectrometry : RCM 20070101
Determining enediol compounds in tea using surface-assisted laser desorption/ionization mass spectrometry with titanium dioxide nanoparticle matrices. Rapid communications in mass spectrometry : RCM 20070101
Matrix-assisted laser desorption/ionization mass spectrometry of polysaccharides with 2',4',6'-trihydroxyacetophenone as matrix. Rapid communications in mass spectrometry : RCM 20070101
Differential effects of hydroxyacetophenone analogues on the transcytotic vesicular pathway in rat liver. European journal of pharmacology 20061010
Detection of phosphopeptides using Fe(III)-nitrilotriacetate complexes immobilized on a MALDI plate. Analytical chemistry 20060301
Inhibitory effects of choleretic hydroxyacetophenones on ileal bile acid transport in rats. Life sciences 20060227
Complete MALDI-ToF MS analysis of cross-linked peptide-RNA oligonucleotides derived from nonlabeled UV-irradiated ribonucleoprotein particles. RNA (New York, N.Y.) 20051201
Induction of human cholesterol 7alpha-hydroxylase in HepG2 cells by 2,4,6-trihydroxyacetophenone. European journal of pharmacology 20050516
Rapid separation of antimicrobial metabolites by microchip electrophoresis with UV linear imaging detection. Journal of chromatography. A 20050415
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of 4-sulfophenyl isothiocyanate-derivatized peptides on AnchorChip sample supports using the sodium-tolerant matrix 2,4,6-trihydroxyacetophenone and diammonium citrate. Rapid communications in mass spectrometry : RCM 20050101
[Determination of oligonucleotide molecular masses by MS-MALDI]. Bioorganicheskaia khimiia 20050101
Defense responses of Fusarium oxysporum to 2,4-diacetylphloroglucinol, a broad-spectrum antibiotic produced by Pseudomonas fluorescens. Molecular plant-microbe interactions : MPMI 20041101
Rapid analysis of antimicrobial metabolites monoacetylphloroglucinol and 2,4-diacetylphloroglucinol using capillary zone electrophoresis. Electrophoresis 20040601
Enhanced ionization of phosphorylated peptides during MALDI TOF mass spectrometry. Analytical chemistry 20040301
Chromone studies. Part 13. Synthesis and electron-impact mass spectrometric studies of 5-hydroxy-2-isopropyl-7-methoxychromone, a constituent of the medicinal plant Baeckea frutescens, and side-chain analogues. Journal of natural products 20030801
Cholesterol lowering effects of a choleretic phloracetophenone in hypercholesterolemic hamsters. European journal of pharmacology 20020329
Evaluation of the acute and subacute toxicity of a choleretic phloracetophenone in experimental animals. Toxicology letters 20020324
Sodium-tolerant matrix for matrix-assisted laser desorption/ionization mass spectrometry and post-source decay of oligonucleotides. Rapid communications in mass spectrometry : RCM 20020101
Involvement of gacS and rpoS in enhancement of the plant growth-promoting capabilities of Enterobacter cloacae CAL2 and UW4. Canadian journal of microbiology 20010801
Investigating the molecular heterogeneity of polysorbate emulsifiers by MALDI-TOF MS. Journal of agricultural and food chemistry 20010701
A rapid polymerase chain reaction-based assay characterizing rhizosphere populations of 2,4-diacetylphloroglucinol-producing bacteria. Phytopathology 20010101
Properties