Home Other Building Blocks Nicotinoyl-glycine

Nicotinoyl-glycine

CAS No.:
583-08-4
Catalog Number:
AG003F3X
Molecular Formula:
C8H8N2O3
Molecular Weight:
180.1607
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$50
- +
5g
95%
In Stock USA
United States
$150
- +
25g
95%
In Stock USA
United States
$475
- +
Product Description
Catalog Number:
AG003F3X
Chemical Name:
Nicotinoyl-glycine
CAS Number:
583-08-4
Molecular Formula:
C8H8N2O3
Molecular Weight:
180.1607
MDL Number:
MFCD00023578
IUPAC Name:
2-(pyridine-3-carbonylamino)acetic acid
InChI:
InChI=1S/C8H8N2O3/c11-7(12)5-10-8(13)6-2-1-3-9-4-6/h1-4H,5H2,(H,10,13)(H,11,12)
InChI Key:
ZBSGKPYXQINNGF-UHFFFAOYSA-N
SMILES:
OC(=O)CNC(=O)c1cccnc1
EC Number:
209-497-0
UNII:
77V5315PIU
NSC Number:
71273
Properties
Complexity:
206  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
180.053g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
180.163g/mol
Monoisotopic Mass:
180.053g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
79.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.4  
Literature
Title Journal
Simultaneous quantification of niacin and its three main metabolites in human plasma by LC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901
Beneficial metabolic effects of 2',3',5'-tri-acetyl-N6- (3-hydroxylaniline) adenosine in the liver and plasma of hyperlipidemic hamsters. PloS one 20120101
Assessment of potential pharmacokinetic interactions of ezetimibe/simvastatin and extended-release niacin tablets in healthy subjects. European journal of clinical pharmacology 20110501
Feedback modeling of non-esterified fatty acids in rats after nicotinic acid infusions. Journal of pharmacokinetics and pharmacodynamics 20110201
Pharmacokinetics and dose recommendations of Niaspan® in chronic kidney disease and dialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101
Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni. Parasites & vectors 20110101
[Determination of nicacid and its metabolites in human plasma by HPLC-MS/MS]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101
Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. Biomedical chromatography : BMC 20101001
Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. Journal of nucleic acids 20100101
A comparison of the pharmacokinetics of two different formulations of extended-release niacin. Current medical research and opinion 20090101
Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM). Bioorganic & medicinal chemistry 20081201
Targeting multiple dyslipidemias with fixed combinations--focus on extended release niacin and simvastatin. Vascular health and risk management 20081001
Analysis of time-related metabolic fluctuations induced by ethionine in the rat. Journal of proteome research 20071201
The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. Biopharmaceutics & drug disposition 20070901
Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation. International journal of clinical pharmacology and therapeutics 20070801
Nicotinic acid induces secretion of prostaglandin D2 in human macrophages: an in vitro model of the niacin flush. Atherosclerosis 20070601
Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites. Journal of clinical pharmacology 20070601
Azabicyclic amino acids by stereoselective dearomatizing cyclization of the enolates of N-nicotinoyl glycine derivatives. Organic letters 20061109
Simultaneous determination of niacin, niacinamide and nicotinuric acid in human plasma. Journal of pharmaceutical and biomedical analysis 20050104
Simultaneous determination of nicotinic acid and its metabolites using hydrophilic interaction chromatography with tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20050101
Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats. Bioscience, biotechnology, and biochemistry 20040101
Synthesis and asymmetric reducing performance of chitin/dihydronicotinamide conjugates having glycine or L-leucine spacer arms. Biomacromolecules 20020101
Properties