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1-Phenylthiourea

CAS No.:
103-85-5
Catalog Number:
AG003EMX
Molecular Formula:
C7H8N2S
Molecular Weight:
152.2168
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
>98.0%(HPLC)(N)
1 week
United States
$98
- +
500g
>98.0%(HPLC)(N)
1 week
United States
$521
- +
Product Description
Catalog Number:
AG003EMX
Chemical Name:
1-Phenylthiourea
CAS Number:
103-85-5
Molecular Formula:
C7H8N2S
Molecular Weight:
152.2168
MDL Number:
MFCD00004933
IUPAC Name:
phenylthiourea
InChI:
InChI=1S/C7H8N2S/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10)
InChI Key:
FULZLIGZKMKICU-UHFFFAOYSA-N
SMILES:
NC(=S)Nc1ccccc1
EC Number:
203-151-2
UNII:
6F82C6Q54C
NSC Number:
5779
RTECS Number:
YU1400000
Properties
Complexity:
119  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
152.041g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
152.215g/mol
Monoisotopic Mass:
152.041g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
70.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.7  
Literature
Title Journal
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Behavioral analysis of Drosophila transformants expressing human taste receptor genes in the gustatory receptor neurons. Journal of neurogenetics 20120601
Diafenthiuron residue and decline in pakchoi and soil under field application. Ecotoxicology and environmental safety 20120501
Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa. Molecular biology and evolution 20120401
Infection of honey bees with acute bee paralysis virus does not trigger humoral or cellular immune responses. Archives of virology 20120401
Preparation of cross-linked magnetic chitosan-phenylthiourea resin for adsorption of Hg(II), Cd(II) and Zn(II) ions from aqueous solutions. Journal of hazardous materials 20120330
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Unique domain appended to vertebrate tRNA synthetase is essential for vascular development. Nature communications 20120221
The phenylthiourea is a competitive inhibitor of the enzymatic oxidation of DOPA by phenoloxidase. Journal of enzyme inhibition and medicinal chemistry 20120201
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Neurospora crassa Light Signal Transduction Is Affected by ROS. Journal of signal transduction 20120101
RP-LC of phenylthiocarbamyl amino acid adducts in plasma acetonitrile extracts: use of multiple internal standards and variable wavelength UV detection. Methods in molecular biology (Clifton, N.J.) 20120101
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Responsiveness to 6-n-propylthiouracil (PROP) is associated with salivary levels of two specific basic proline-rich proteins in humans. PloS one 20120101
In vitro murine leukemia retroviral integration and structure fluctuation of target DNA. PloS one 20120101
A proteomic view on the developmental transfer of homologous 30 kDa lipoproteins from peripheral fat body to perivisceral fat body via hemolymph in silkworm, Bombyx mori. BMC biochemistry 20120101
Cell-autonomous alterations in dendritic arbor morphology and connectivity induced by overexpression of MeCP2 in Xenopus central neurons in vivo. PloS one 20120101
Identification and analysis of conserved cis-regulatory regions of the MEIS1 gene. PloS one 20120101
Analysis of expressed sequence tags and characterization of a novel gene, Slmg7, in the midgut of the common cutworm, Spodoptera litura. PloS one 20120101
Electronic tongue: An analytical gustatory tool. Journal of advanced pharmaceutical technology & research 20120101
Wnt3 and Wnt3a are required for induction of the mid-diencephalic organizer in the caudal forebrain. Neural development 20120101
Zebrafish Agr2 is required for terminal differentiation of intestinal goblet cells. PloS one 20120101
High hemocyte load is associated with increased resistance against parasitoids in Drosophila suzukii, a relative of D. melanogaster. PloS one 20120101
PEDF and VEGF-A output from human retinal pigment epithelial cells grown on novel microcarriers. Journal of biomedicine & biotechnology 20120101
Genetic variation of an odorant receptor OR7D4 and sensory perception of cooked meat containing androstenone. PloS one 20120101
Miniaturized embryo array for automated trapping, immobilization and microperfusion of zebrafish embryos. PloS one 20120101
The viral TRAF protein (ORF111L) from infectious spleen and kidney necrosis virus interacts with TRADD and induces caspase 8-mediated apoptosis. PloS one 20120101
Role of phenylthiocarbamide as a genetic marker in predicting the predisposition of disease traits in humans. Journal of natural science, biology, and medicine 20120101
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Phenylthiourea specifically reduces zebrafish eye size. PloS one 20120101
Effects of known phenoloxidase inhibitors on hemocyanin-derived phenoloxidase from Limulus polyphemus. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120101
First evidence of a potential antibacterial activity involving a laccase-type enzyme of the phenoloxidase system in Pacific oyster Crassostrea gigas haemocytes. Fish & shellfish immunology 20111201
Lyn is a redox sensor that mediates leukocyte wound attraction in vivo. Nature 20111201
Lhx2 and Lhx9 determine neuronal differentiation and compartition in the caudal forebrain by regulating Wnt signaling. PLoS biology 20111201
Structural requirement of phenylthiourea analogs for their inhibitory activity of melanogenesis and tyrosinase. Bioorganic & medicinal chemistry letters 20111115
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Integration of CNS survival and differentiation by HIF2α. Cell death and differentiation 20111101
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N-(4-Hy-droxy-phen-yl)-3,4,5-trimeth-oxy-benzamide. Acta crystallographica. Section E, Structure reports online 20111101
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Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish. Development (Cambridge, England) 20111015
Histone deacetylase activators: N-acetylthioureas serve as highly potent and isozyme selective activators for human histone deacetylase-8 on a fluorescent substrate. Bioorganic & medicinal chemistry letters 20111001
Photodynamic therapy-induced killing is enhanced in depigmented metastatic melanoma cells. Cell biology international 20110901
Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Disease models & mechanisms 20110901
Colorimetric detection of cyanide with phenyl thiourea derivatives. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901
Purification and characterization of phenoloxidase from brine shrimp Artemia sinica. Acta biochimica et biophysica Sinica 20110901
Stearoyl-CoA desaturase is an essential enzyme for the parasitic protist Trypanosoma brucei. Biochemical and biophysical research communications 20110826
Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK. The Biochemical journal 20110815
Facile synthesis of carbohydrate-integrated isoxazolines through tandem [4+1] cycloaddition and rearrangement of 2-nitroglycals. Chemical communications (Cambridge, England) 20110814
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Celsr3 is required for normal development of GABA circuits in the inner retina. PLoS genetics 20110801
6-n-propylthiouracil taster status not related to reported cruciferous vegetable intake among ethnically diverse children. Nutrition research (New York, N.Y.) 20110801
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Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component. Disease models & mechanisms 20110701
Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process. Bioorganic & medicinal chemistry 20110701
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The oriented emergence of axons from retinal ganglion cells is directed by laminin contact in vivo. Neuron 20110428
The N-terminal region of centrosomal protein 290 (CEP290) restores vision in a zebrafish model of human blindness. Human molecular genetics 20110415
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Identification of a potent and noncytotoxic inhibitor of melanin production. Bioorganic & medicinal chemistry 20100801
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(-)-N-Formylanonaine from Michelia alba as a human tyrosinase inhibitor and antioxidant. Bioorganic & medicinal chemistry 20100715
Evolving neural network optimization of cholesteryl ester separation by reversed-phase HPLC. Analytical and bioanalytical chemistry 20100701
Toxicity of diafenthiuron to honey bees in laboratory, semi-field and field conditions. Pest management science 20100501
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Structural requirement(s) of N-phenylthioureas and benzaldehyde thiosemicarbazones as inhibitors of melanogenesis in melanoma B 16 cells. Bioorganic & medicinal chemistry letters 20100501
Computational processing of optical measurements of neuronal and synaptic activity in networks. Journal of neuroscience methods 20100430
First evidence of laccase activity in the Pacific oyster Crassostrea gigas. Fish & shellfish immunology 20100401
N-(2-Bromo-phen-yl)thio-urea. Acta crystallographica. Section E, Structure reports online 20100401
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Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern. Developmental biology 20100115
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Silicon switch approach in TRPV1 antagonist MK-056 and its analogues. Bioorganic & medicinal chemistry 20100101
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Immunity and other defenses in pea aphids, Acyrthosiphon pisum. Genome biology 20100101
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Phenotypic analysis of images of zebrafish treated with Alzheimer's gamma-secretase inhibitors. BMC biotechnology 20100101
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Smell perception in normal tension glaucoma patients. Molecular vision 20100101
Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. Neural development 20100101
Chemical modulators of the innate immune response alter gypsy moth larval susceptibility to Bacillus thuringiensis. BMC microbiology 20100101
Functional conservation of a forebrain enhancer from the elephant shark (Callorhinchus milii ) in zebrafish and mice. BMC evolutionary biology 20100101
Atoh8, a bHLH transcription factor, is required for the development of retina and skeletal muscle in zebrafish. PloS one 20100101
A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer. BMC medical genetics 20100101
Platelet-derived growth factor receptor beta is critical for zebrafish intersegmental vessel formation. PloS one 20100101
Age modifies the genotype-phenotype relationship for the bitter receptor TAS2R38. BMC genetics 20100101
Evolution of a bitter taste receptor gene cluster in a New World sparrow. Genome biology and evolution 20100101
A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development. BMC developmental biology 20100101
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Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system. Neural development 20100101
Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor. PloS one 20100101
Expression of immune-response genes in lepidopteran host is suppressed by venom from an endoparasitoid, Pteromalus puparum. BMC genomics 20100101
In vivo imaging of zebrafish retinal cells using fluorescent coumarin derivatives. BMC neuroscience 20100101
Sensitivity to bitter and sweet taste perception in schoolchildren and their relation to dental caries. Oral health & preventive dentistry 20100101
Duplicate dmbx1 genes regulate progenitor cell cycle and differentiation during zebrafish midbrain and retinal development. BMC developmental biology 20100101
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Pdlim7 is required for maintenance of the mesenchymal/epidermal Fgf signaling feedback loop during zebrafish pectoral fin development. BMC developmental biology 20100101
Multicolor time-lapse imaging of transgenic zebrafish: visualizing retinal stem cells activated by targeted neuronal cell ablation. Journal of visualized experiments : JoVE 20100101
Optogenetic in vivo cell manipulation in KillerRed-expressing zebrafish transgenics. BMC developmental biology 20100101
In the absence of Sonic hedgehog, p53 induces apoptosis and inhibits retinal cell proliferation, cell-cycle exit and differentiation in zebrafish. PloS one 20100101
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Purification of lectin from larvae of the fly, Musca domestica, and in vitro anti-tumor activity in MCF-7 cells. Journal of insect science (Online) 20100101
Bitter receptor gene (TAS2R38) P49A genotypes and their associations with aversion to vegetables and sweet/fat foods in Malaysian subjects. Asia Pacific journal of clinical nutrition 20100101
Loss of cofilin 1 disturbs actin dynamics, adhesion between enveloping and deep cell layers and cell movements during gastrulation in zebrafish. PloS one 20100101
Visualization of Gli activity in craniofacial tissues of hedgehog-pathway reporter transgenic zebrafish. PloS one 20100101
Bitter taste perception in Neanderthals through the analysis of the TAS2R38 gene. Biology letters 20091223
Selective neuronal requirement for huntingtin in the developing zebrafish. Human molecular genetics 20091215
A double-blind study of the influences of eszopiclone on dysgeusia and taste function. Pharmacology, biochemistry, and behavior 20091201
The hunt for natural skin whitening agents. International journal of molecular sciences 20091201
A non-synonymous variant in ADH1B is strongly associated with prenatal alcohol use in a European sample of pregnant women. Human molecular genetics 20091115
Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity. Bioorganic & medicinal chemistry letters 20091115
Solid phase extraction of gold(III) on silica gel modified with benzoylthiourea prior to its determination by flame atomic absorption spectrometry. Environmental monitoring and assessment 20091101
Basonuclin-2 requirements for zebrafish adult pigment pattern development and female fertility. PLoS genetics 20091101
N-(Acetamido)thiourea based simple neutral hydrogen-bonding receptors for anions. Organic & biomolecular chemistry 20091007
Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway. Pigment cell & melanoma research 20091001
Purification and characterization of phenoloxidase from Octopus ocellatus. Acta biochimica et biophysica Sinica 20091001
Light directs zebrafish period2 expression via conserved D and E boxes. PLoS biology 20091001
Role of the ubiquitin proteasome system in regulating skin pigmentation. International journal of molecular sciences 20091001
Actomyosin is the main driver of interkinetic nuclear migration in the retina. Cell 20090918
Influence of melanosome dynamics on melanoma drug sensitivity. Journal of the National Cancer Institute 20090916
The expression of nr0b1, the earliest gene in zebrafish tooth development, is a marker for human tooth and ameloblastoma formation. Development genes and evolution 20090801
The mode of action of venom from the endoparasitic wasp Pimpla hypochondriaca (hymenoptera: ichneumonidae) involves Ca+2-dependent cell death pathways. Archives of insect biochemistry and physiology 20090701
Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes. PLoS genetics 20090701
Genetic variation in taste sensitivity to 6-n-propylthiouracil and its relationship to taste perception and food selection. Annals of the New York Academy of Sciences 20090701
Nucleotide-responsive wettability on a smart polymer surface. Journal of the American Chemical Society 20090624
Solid phase extraction of mercury on sulfur loaded with N-(2-chloro benzoyl)-N'-phenylthiourea as a new adsorbent and determination by cold vapor atomic absorption spectrometry. Talanta 20090615
Synthesis of phenylisothiourea derivatives as inhibitors of NO production in LPS activated macrophages. Bioorganic & medicinal chemistry letters 20090601
Nanomolar Hg(II) detection using Nile blue chemodosimeter in biological media. Organic letters 20090521
Ethyl 4-(2,4-difluoro-phen-yl)-6-methyl-1-phenyl-2-thioxo-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20090501
Structural stability, C--N internal rotations and vibrational spectral analysis of non-planar phenylurea and phenylthiourea. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090401
Identification and characterization of a hemocyanin-derived phenoloxidase from the crab Charybdis japonica. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20090201
Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene. Human molecular genetics 20090115
Synthesis and anticonvulsant activity of new N-(alkyl/sub-stituted aryl)-N'-[4-(5-cyclohexylamino)-1,3,4-thiadiazole-2-yl)phenyl]thioureas. Archiv der Pharmazie 20090101
Noninvasive technique for measurement of heartbeat regularity in zebrafish (Danio rerio) embryos. BMC biotechnology 20090101
Two-photon axotomy and time-lapse confocal imaging in live zebrafish embryos. Journal of visualized experiments : JoVE 20090101
Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains. Molecular neurodegeneration 20090101
Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. BMC cell biology 20090101
The phytoestrogen genistein affects zebrafish development through two different pathways. PloS one 20090101
A novel puf-A gene predicted from evolutionary analysis is involved in the development of eyes and primordial germ-cells. PloS one 20090101
Role of the 2 zebrafish survivin genes in vasculo-angiogenesis, neurogenesis, cardiogenesis and hematopoiesis. BMC developmental biology 20090101
Vsx2 in the zebrafish retina: restricted lineages through derepression. Neural development 20090101
Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae. BMC biotechnology 20090101
Mosaic hoxb4a neuronal pleiotropism in zebrafish caudal hindbrain. PloS one 20090101
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Genetic and molecular basis of individual differences in human umami taste perception. PloS one 20090101
Labelling and targeted ablation of specific bipolar cell types in the zebrafish retina. BMC neuroscience 20090101
Ptf1a is expressed transiently in all types of amacrine cells in the embryonic zebrafish retina. Neural development 20090101
Zebrafish con/disp1 reveals multiple spatiotemporal requirements for Hedgehog-signaling in craniofacial development. BMC developmental biology 20090101
A genome-wide survey for host response of silkworm, Bombyx mori during pathogen Bacillus bombyseptieus infection. PloS one 20090101
Critical early roles for col27a1a and col27a1b in zebrafish notochord morphogenesis, vertebral mineralization and post-embryonic axial growth. PloS one 20090101
TAS2R38 genotypes and phenylthiocarbamide bitter taste perception in a population of young adults. Journal of nutrigenetics and nutrigenomics 20090101
Drugs impact on CYP-450 enzyme family: A pharmacogenetical study of response variation. Indian journal of human genetics 20090101
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients. Hepatology (Baltimore, Md.) 20081201
Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells. PLoS genetics 20081201
DNA-small molecule chimera with responsive protein-binding ability. Journal of the American Chemical Society 20081112
Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2. The Journal of biological chemistry 20081017
Phenylthiocarbamide taste perception and susceptibility to motion sickness: linking higher susceptibility with higher phenylthiocarbamide taste acuity. The Journal of laryngology and otology 20081001
Purification and characterization of hemolymph prophenoloxidase from Ostrinia furnacalis (Lepidoptera: Pyralidae) larvae. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20081001
Diurnal variation of human sweet taste recognition thresholds is correlated with plasma leptin levels. Diabetes 20081001
Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy. International journal of cancer 20080915
The prophenoloxidase system is activated during the tunic inflammatory reaction of Ciona intestinalis. Cell and tissue research 20080901
Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish. PLoS genetics 20080901
L-DOPA is an endogenous ligand for OA1. PLoS biology 20080901
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Regulation of eumelanin/pheomelanin synthesis and visible pigmentation in melanocytes by ligands of the melanocortin 1 receptor. Pigment cell & melanoma research 20080801
The identification of zebrafish mutants showing alterations in senescence-associated biomarkers. PLoS genetics 20080801
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Birth of a new breed of supertaster. Chemical senses 20080701
Positional cloning of 'Lisch-Like', a candidate modifier of susceptibility to type 2 diabetes in mice. PLoS genetics 20080701
Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. Bioorganic & medicinal chemistry letters 20080615
Synthesis and structure of monomeric, trimeric, and mixed phenylcyanamides. Chemistry, an Asian journal 20080602
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Comparing sensory experience in bitter taste perception of phenylthiocarbamide within and between human twins and singletons: intrapair differences in thresholds and genetic variance estimates. Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur 20080601
Synergy of a hepatitis C virus (HCV) NS4A antagonist in combination with HCV protease and polymerase inhibitors. Antimicrobial agents and chemotherapy 20080501
Kinetic properties of catecholoxidase activity of tarantula hemocyanin. The FEBS journal 20080401
Supertasting and PROP bitterness depends on more than the TAS2R38 gene. Chemical senses 20080301
RBP4 disrupts vitamin A uptake homeostasis in a STRA6-deficient animal model for Matthew-Wood syndrome. Cell metabolism 20080301
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Role of CCK1 and Y2 receptors in activation of hindbrain neurons induced by intragastric administration of bitter taste receptor ligands. American journal of physiology. Regulatory, integrative and comparative physiology 20080101
Tissue-specific requirements for specific domains in the FERM protein Moe/Epb4.1l5 during early zebrafish development. BMC developmental biology 20080101
Genomewide expression analysis in zebrafish mind bomb alleles with pancreas defects of different severity identifies putative Notch responsive genes. PloS one 20080101
Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes. PloS one 20080101
Prevalence of common disease-associated variants in Asian Indians. BMC genetics 20080101
Cyanide sensing with organic dyes: studies in solution and on nanostructured Al2O3 surfaces. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Brain asymmetry is encoded at the level of axon terminal morphology. Neural development 20080101
Nutritional implications of genetic taste variation: the role of PROP sensitivity and other taste phenotypes. Annual review of nutrition 20080101
Kinetic properties of hexameric tyrosinase from the crustacean Palinurus elephas. Photochemistry and photobiology 20080101
In vivo analysis of choroid plexus morphogenesis in zebrafish. PloS one 20080101
Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish. BMC developmental biology 20080101
Distinct roles of Shh and Fgf signaling in regulating cell proliferation during zebrafish pectoral fin development. BMC developmental biology 20080101
Domain-specific regulation of foxP2 CNS expression by lef1. BMC developmental biology 20080101
Impact of genetic and environmental determinants of taste with food preferences in older adults. Journal of nutrition for the elderly 20080101
Bitter taste receptors influence glucose homeostasis. PloS one 20080101
Targeting retinal dopaminergic neurons in tyrosine hydroxylase-driven green fluorescent protein transgenic zebrafish. Molecular vision 20080101
Effect of norharmane in vitro on juvenile hormone epoxide hydrolase activity in the lower termite, Reticulitermes speratus. Journal of insect science (Online) 20080101
Depigmentation of melanocytes by isopanduratin A and 4-hydroxypanduratin A isolated from Kaempferia pandurata ROXB. Biological & pharmaceutical bulletin 20071101
Twin study of the heritability of recognition thresholds for sour and salty taste. Chemical senses 20071001
Interaction between myosin heavy chain and troponin isoforms modulate cardiac myofiber contractile dynamics. American journal of physiology. Regulatory, integrative and comparative physiology 20071001
Lack of support for the inability to taste phenylthiocarbamide as an endophenotypic marker in patients with schizophrenia and their first-degree relatives. Schizophrenia research 20070901
Phenylthiocarbamide (PTC) perception in Parkinson disease. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20070901
Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. Current biology : CB 20070821
Tracking of mercury ions in living cells with a fluorescent chemodosimeter under single- or two-photon excitation. Analytica chimica acta 20070806
TRP-ing up melanophores: TRPM7, melanin synthesis, and pigment cell survival. The Journal of investigative dermatology 20070801
The effect of dialysis membrane flux on amino acid loss in hemodialysis patients. Journal of Korean medical science 20070801
Modest thyroid hormone insufficiency during development induces a cellular malformation in the corpus callosum: a model of cortical dysplasia. Endocrinology 20070601
Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish. PLoS genetics 20070601
Demonstration of a true phenoloxidase activity and activation of a ProPO cascade in Pacific oyster, Crassostrea gigas (Thunberg) in vitro. Fish & shellfish immunology 20070401
Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds. Pigment cell research 20070401
Variation in oral sensation: implications for diet and health. Current opinion in gastroenterology 20070301
A review of the risk factors in primary open angle glaucoma. Nigerian journal of clinical practice 20070301
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Direct calorimetry of free-moving eels with manipulated thyroid status. Die Naturwissenschaften 20070201
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Electroporation-based methods for in vivo, whole mount and primary culture analysis of zebrafish brain development. Neural development 20070101
The disarrayed mutation results in cell cycle and neurogenesis defects during retinal development in zebrafish. BMC developmental biology 20070101
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The chemokine Sdf-1 and its receptor Cxcr4 are required for formation of muscle in zebrafish. BMC developmental biology 20070101
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Pbx homeodomain proteins pattern both the zebrafish retina and tectum. BMC developmental biology 20070101
Expression of the zebrafish intermediate neurofilament Nestin in the developing nervous system and in neural proliferation zones at postembryonic stages. BMC developmental biology 20070101
Refining associations between TAS2R38 diplotypes and the 6-n-propylthiouracil (PROP) taste test: findings from the Avon Longitudinal Study of Parents and Children. BMC genetics 20070101
Nutrigenomics of taste - impact on food preferences and food production. Forum of nutrition 20070101
Behavioral genetics and taste. BMC neuroscience 20070101
Porphobilinogen synthase from the butterfly, Pieris brassicae: purification and comparative characterization. Journal of insect science (Online) 20070101
Evolution of phenylthiocarbamide taster trait in Mysore, South India. Indian journal of human genetics 20070101
Differences in smoking-related variables based on phenylthiocarbamide 'taster' status. Addictive behaviors 20061201
Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. American journal of physiology. Gastrointestinal and liver physiology 20061101
Epidermal transient down-regulation of retinol-binding protein 4 and mirror expression of apolipoprotein Eb and estrogen receptor 2a during zebrafish fin and scale development. Developmental dynamics : an official publication of the American Association of Anatomists 20061101
Bitter stimuli induce Ca2+ signaling and CCK release in enteroendocrine STC-1 cells: role of L-type voltage-sensitive Ca2+ channels. American journal of physiology. Cell physiology 20061001
A potential novel mechanism involving connexin 43 gap junction for control of sertoli cell proliferation by thyroid hormones. Journal of cellular physiology 20061001
Dose-dependent effects of chemical immobilization on the heart rate of embryonic zebrafish. Lab animal 20061001
Modeling the human PTC bitter-taste receptor interactions with bitter tastants. Journal of molecular modeling 20060901
Associations of phenylthiocarbamide tasting to alcohol problems and family history of alcoholism differ by gender. Psychiatry research 20060630
s-Benzylthiuronium PVC matrix membrane sensor for potentiometric determination of cationic surfactants in some pharmaceutical formulation. Journal of pharmaceutical and biomedical analysis 20060616
Human glioblastoma ADF cells express tyrosinase, L-tyrosine hydroxylase and melanosomes and are sensitive to L-tyrosine and phenylthiourea. Journal of cellular physiology 20060601
The relationship between phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) taster status and taste thresholds for sucrose and quinine. Archives of oral biology 20060501
Conformational preferences and internal rotation in alkyl- and phenyl-substituted thiourea derivatives. The journal of physical chemistry. A 20060413
Independent evolution of bitter-taste sensitivity in humans and chimpanzees. Nature 20060413
Phenylthiocarbamide: a 75-year adventure in genetics and natural selection. Genetics 20060401
Regulation of melanin synthesis by selenium-containing carbohydrates. Chemical & pharmaceutical bulletin 20060301
A unique NH-spacer for N-benzamidothiourea based anion sensors. Substituent effect on anion sensing of the ICT dual fluorescent N-(p-dimethylaminobenzamido)-N'-arylthioureas. Organic & biomolecular chemistry 20060221
Synthesis and in vitro antitubercular activity of some 1-[(4-sub)phenyl]-3-(4-{1-[(pyridine-4-carbonyl)hydrazono]ethyl}phenyl)thiourea. Bioorganic & medicinal chemistry letters 20060215
Purification and characterization of phenoloxidase from crab Charybdis japonica. Fish & shellfish immunology 20060101
Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents. Bioorganic & medicinal chemistry letters 20060101
Clinically useful vanilloid receptor TRPV1 antagonists: just around the corner (or too early to tell)? Progress in medicinal chemistry 20060101
The human sweet tooth. BMC oral health 20060101
Computational studies of ligand-receptor interactions in bitter taste receptors. Journal of receptor and signal transduction research 20060101
Polarization and orientation of retinal ganglion cells in vivo. Neural development 20060101
Use of growth regulator of cytokinin type for enhancement and modification of herbicide activity. Communications in agricultural and applied biological sciences 20060101
Plasma phenoloxidase of the larval tobacco budworm, Heliothis virescens, is virucidal. Journal of insect science (Online) 20060101
Laccase-type phenoloxidase in salivary glands and watery saliva of the green rice leafhopper, Nephotettix cincticeps. Journal of insect physiology 20051201
Associations between phenylthiocarbamide gene polymorphisms and cigarette smoking. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20051201
1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists. Journal of medicinal chemistry 20051117
Alkylating benzamides with melanoma cytotoxicity: role of melanin, tyrosinase, intracellular pH and DNA interaction. Melanoma research 20051001
Founder mutations. Scientific American 20051001
Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci. Human mutation 20050901
Purification and characterisation of phenoloxidase from amphioxus Branchiostoma belcheri tsingtauense. Fish & shellfish immunology 20050801
Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat. Physiological genomics 20050714
Genetic analysis of reproduction in the Buryat populations. Journal of physiological anthropology and applied human science 20050701
Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar. PLoS genetics 20050701
Phenylthiocarbamide produces conditioned taste aversions in mice. Chemical senses 20050601
The relationship between PTC taster status and taste thresholds in young adults. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20050601
Genetics of individual differences in bitter taste perception: lessons from the PTC gene. Clinical genetics 20050401
Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation. Pigment cell research 20050401
Phenylthiocarbamide perception in patients with schizophrenia and first-degree family members. The American journal of psychiatry 20050401
The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception. Current biology : CB 20050222
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1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents. Bioorganic & medicinal chemistry letters 20050201
Thermogravimetric studies of benzoylthiourea-modified MCM-41 after adsorption of mercury ions from aqueous solutions. The Analyst 20050101
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Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice. BMC genetics 20050101
Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli. BMC genetics 20050101
Human taste genetics. Annual review of genomics and human genetics 20050101
Identification and partial characterization of the enzyme of omega: one of five putative DPP IV genes in Drosophila melanogaster. Journal of insect science (Online) 20050101
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Structure-activity relationship of S-benzylisothiourea derivatives to induce spherical cells in Escherichia coli. Bioscience, biotechnology, and biochemistry 20041101
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Analysis of structure-activity relationships with the N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea template for vanilloid receptor 1 antagonism. Bioorganic & medicinal chemistry 20040701
Genetics of human taste perception. Journal of dental research 20040601
Possible relationship between phenylthiocarbamide taste sensitivity and epilepsy. Neurology India 20040601
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione. Chemical research in toxicology 20040501
Phenylthiocarbamide tasting and family history of depression, revisited: low rates of depression in families of supertasters. Psychiatry research 20040415
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Synergistic drug combinations against the in vitro replication of Coxsackie B1 virus. Antiviral research 20040401
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Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis. The Journal of biological chemistry 20031226
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Versatile access to benzhydryl-phenylureas through an unexpected rearrangement during microwave-enhanced synthesis of hydantoins. Organic letters 20031002
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Combined effect of dopamine and MPP+ on membrane permeability in mitochondria and cell viability in PC12 cells. Neurochemistry international 20030701
Genetic analysis of a complex trait in the Utah Genetic Reference Project: a major locus for PTC taste ability on chromosome 7q and a secondary locus on chromosome 16p. Human genetics 20030501
Scientist finds gene that determines major sensitivity to bitter taste. Journal of the California Dental Association 20030401
Truffle thio-flavours reversibly inhibit truffle tyrosinase. FEMS microbiology letters 20030314
Elimination of shrimp endogenous peroxidase background in immunodot blot assays to detect white spot syndrome virus (WSSV). Diseases of aquatic organisms 20030227
Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science (New York, N.Y.) 20030221
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A new member of the GM130 golgin subfamily is expressed in the optic lobe anlagen of the metamorphosing brain of Manduca sexta. Journal of insect science (Online) 20030101
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Dissipation of foliar residues of diafenthiuron and its metabolites. Bulletin of environmental contamination and toxicology 20020601
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Application of the artificial neural network in quantitative structure-gradient elution retention relationship of phenylthiocarbamyl amino acids derivatives. Journal of pharmaceutical and biomedical analysis 20020515
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3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents. Chemical & pharmaceutical bulletin 20011201
Catalytic hydrogen evolution in cathodic stripping voltammetry on a mercury electrode in the presence of cobalt(II) ion and phenylthiourea or thiourea. The Analyst 20011101
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