Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury.

Archives of toxicology 20170101

Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach.

Archives of toxicology 20170101

Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development.

Toxicology letters 20161130

Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice.

Toxicology and applied pharmacology 20160901

Alpha-naphthylisothiocyanate impairs bile acid homeostasis through AMPK-FXR pathways in rat primary hepatocytes.

Toxicology 20160831

Dioscin protects against ANIT-induced cholestasis via regulating Oatps, Mrp2 and Bsep expression in rats.

Toxicology and applied pharmacology 20160815

Promising toxicological biomarkers for the diagnosis of liver injury types: Bile acid metabolic profiles and oxidative stress marker as screening tools in drug development.

Chemico-biological interactions 20160805

Inhibition of PAR-4 and P2Y12 receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease.

Toxicology 20160715

Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism.

Blood 20160602

Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.

Chemical research in toxicology 20160321

Onset of hepatocarcinogen-specific cell proliferation and cell cycle aberration during the early stage of repeated hepatocarcinogen administration in rats.

Journal of applied toxicology : JAT 20160201

Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.

Toxicological sciences : an official journal of the Society of Toxicology 20150601

Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis.

Toxicology and applied pharmacology 20150315

Resveratrol effectively attenuates α-naphthyl-isothiocyanate-induced acute cholestasis and liver injury through choleretic and anti-inflammatory mechanisms.

Acta pharmacologica Sinica 20141201

Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice.

Toxicology 20141105

Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats.

Toxicology 20141003

The antifibrinolytic drug tranexamic acid reduces liver injury and fibrosis in a mouse model of chronic bile duct injury.

The Journal of pharmacology and experimental therapeutics 20140601

Metabolomic analysis of arginine metabolism in acute hepatic injury in rats.

The Journal of toxicological sciences 20140201

Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes.

Toxicology letters 20140103

Systems level analysis and identification of pathways and networks associated with liver fibrosis.

PloS one 20140101

Genomic biomarkers for cardiotoxicity in rats as a sensitive tool in preclinical studies.

Journal of applied toxicology : JAT 20131001

Evaluation of miR-122 and other biomarkers in distinct acute liver injury in rats.

Toxicologic pathology 20130701

Expression patterns of cell cycle proteins in the livers of rats treated with hepatocarcinogens for 28 days.

Archives of toxicology 20130601

Loss of A(1) adenosine receptor attenuates alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.

Toxicological sciences : an official journal of the Society of Toxicology 20130101

Changes of pharmacokinetics of 6,7-dimethoxycoumarin in a rat model of alpha-naphthylisothiocyanate-induced experimental hepatic injury after Yinchenhao Decoction () treatment.

Chinese journal of integrative medicine 20121101

Effect of JBP485 on obstructive jaundice is related to regulation of renal Oat1, Oat3 and Mrp2 expression in ANIT-treated rats.

Peptides 20120701

Gender-specific reduction of hepatic Mrp2 expression by high-fat diet protects female mice from ANIT toxicity.

Toxicology and applied pharmacology 20120601

Genetic Variations in TXNRD1 as Potential Predictors of Drug-Induced Liver Injury.

Allergy, asthma & immunology research 20120501

Metabolic profiling of the rat liver after chronic ingestion of alpha-naphthylisothiocyanate using in vivo and ex vivo magnetic resonance spectroscopy.

Toxicological sciences : an official journal of the Society of Toxicology 20120401

Protective effect of Danning tablet on acute livery injury with cholestasis induced by α-naphthylisothiocyanate in rats.

Journal of ethnopharmacology 20120327

Early growth response factor-1 limits biliary fibrosis in a model of xenobiotic-induced cholestasis in mice.

Toxicological sciences : an official journal of the Society of Toxicology 20120301

Mechanism of exacerbative effect of progesterone on drug-induced liver injury.

Toxicological sciences : an official journal of the Society of Toxicology 20120301

Comparative pharmacokinetic study of paeoniflorin and albiflorin after oral administration of Radix Paeoniae Rubra in normal rats and the acute cholestasis hepatitis rats.

Fitoterapia 20120301

Effect of alpha-naphthylisothiocyanate-induced liver injury on intestinal adaptation in a rat model of short bowel syndrome.

Pediatric surgery international 20120201

Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis.

Gastroenterology 20120201

Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat.

American journal of physiology. Gastrointestinal and liver physiology 20120101

Plasma microRNA profiles in rat models of hepatocellular injury, cholestasis, and steatosis.

PloS one 20120101

Identification of biomarkers of chemically induced hepatocarcinogenesis in rasH2 mice by toxicogenomic analysis.

Archives of toxicology 20111201

Pathogenesis of primary sclerosing cholangitis.

Best practice & research. Clinical gastroenterology 20111201

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

PLoS computational biology 20111201

1-[(Ferrocen-1-yl)meth-yl]-3-(naphthalen-1-yl)thio-urea.

Acta crystallographica. Section E, Structure reports online 20111201

Immunohistochemical characterization of macrophages and myofibroblasts in α-Naphthylisothiocyanate (ANIT)--induced bile duct injury and subsequent fibrogenesis in rats.

Toxicologic pathology 20110801

Evaluation study on urine metabolomics in yinhuang rat model induced by triplet factors of rhubarb, ethanol, and α-nephthylisothiolyanate.

Chinese journal of integrative medicine 20110501

Fibrosis in autoimmune and cholestatic liver disease.

Best practice & research. Clinical gastroenterology 20110401

Fibrinogen deficiency increases liver injury and early growth response-1 (Egr-1) expression in a model of chronic xenobiotic-induced cholestasis.

The American journal of pathology 20110301

Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice.

Toxicology and applied pharmacology 20110201

Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury.

Toxicological sciences : an official journal of the Society of Toxicology 20110101

Measuring size-dependent permeability of the tight junction using PEG profiling.

Methods in molecular biology (Clifton, N.J.) 20110101

Hepatotoxicity or hepatoprotection? Pattern recognition for the paradoxical effect of the Chinese herb Rheum palmatum L. in treating rat liver injury.

PloS one 20110101

Existence of inverted profile in chemically responsive molecular pathways in the zebrafish liver.

PloS one 20110101

Protective effects of Moutan Cortex Radicis against acute hepatotoxicity.

African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug metabolism and disposition: the biological fate of chemicals 20101201

The coagulation system contributes to alphaVbeta6 integrin expression and liver fibrosis induced by cholestasis.

The American journal of pathology 20101201

Interleukin-17 is involved in alpha-naphthylisothiocyanate-induced liver injury in mice.

Toxicology 20100910

Time course gene expression using laser capture microscopy-extracted bile ducts, but not hepatic parenchyma, reveals acute alpha-naphthylisothiocyanate toxicity.

Toxicologic pathology 20100801

Acute ANIT toxicity in male IL-10 knockout and wild-type mice.

Toxicologic pathology 20100801

Increased intestinal absorption of mizoribine, an immunosuppressive agent, in cholestatic rats.

Die Pharmazie 20100701

Metabolic Fingerprinting in Toxicological Assessment Using FT-ICR MS.

Journal of toxicologic pathology 20100601

Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies.

Toxicological sciences : an official journal of the Society of Toxicology 20100501

Evaluation of a liver micronucleus assay in young rats (III): a study using nine hepatotoxicants by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS).

Mutation research 20100430

[Effect of emodin on P-gp expression in intrahepatic cholestatic rats].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100401

Identification of urinary biomarkers useful for distinguishing a difference in mechanism of toxicity in rat model of cholestasis.

Basic & clinical pharmacology & toxicology 20090901

Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice.

Toxicological sciences : an official journal of the Society of Toxicology 20090701

Differentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation.

Hepatology (Baltimore, Md.) 20090701

Investigations of free anthraquinones from rhubarb against alpha-naphthylisothiocyanate-induced cholestatic liver injury in rats.

Basic & clinical pharmacology & toxicology 20090601

Comparative study on the protective effects of Yinchenhao Decoction against liver injury induced by alpha-naphthylisothiocyanate and carbon tetrachloride.

Chinese journal of integrative medicine 20090601

Quantitative analysis of valiolamine through pre-column derivatization with phenylisocyanate using high-performance liquid chromatography with UV detection: selection of reagent, identification of derivative and optimization of derivatization conditions.

Journal of pharmaceutical and biomedical analysis 20090501

[Effect and mechanism of emodin on cholestatic hepatitis].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090501

Characterization of the enhancing effect of protamine on the proliferative activity of hepatocyte growth factor in rat hepatocytes.

Pharmaceutical research 20090401

Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice.

American journal of physiology. Gastrointestinal and liver physiology 20090401

ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling.

Toxicological sciences : an official journal of the Society of Toxicology 20090401

Gene expression profiling in rat liver treated with compounds inducing elevation of bilirubin.

Human & experimental toxicology 20090401

[Therapeutic effects of emodin on acute cholestatic hepatitis and mechanism thereof: experiment with rats].

Zhonghua yi xue za zhi 20090317

The impact of new research technologies on our understanding of environmental causes of disease: the concept of clinical vulnerability.

Environmental health : a global access science source 20090101

Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles.

PloS one 20090101

Raman spectral signatures of human liver perfusates correlate with oxidation reduction potential.

Molecular medicine reports 20090101

Monitoring healthy metabolic trajectories with nutritional metabonomics.

Nutrients 20090101

Modulation of the inflammatory response and apoptosis using epidermal growth factor and hepatocyte growth factor in a liver injury model: a potential approach to the management and treatment of cholestatic liver disease.

Journal of pediatric surgery 20081201

Bile acids metabonomic study on the CCl4- and alpha-naphthylisothiocyanate-induced animal models: quantitative analysis of 22 bile acids by ultraperformance liquid chromatography-mass spectrometry.

Chemical research in toxicology 20081201

Urinary metabolic fingerprinting for alpha-naphthylisothiocyanate-induced intrahepatic cholestasis in rats using Fourier transform-ion cyclotron resonance mass spectrometry.

Toxicologic pathology 20081001

In vivo effect of selective macrophage suppression on the development of intrahepatic cholestasis in mice.

Bulletin of experimental biology and medicine 20081001

Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway.

European journal of pharmacology 20080820

A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats.

Toxicology 20080819

Activity of lysosomal enzymes in the bile and serum of mice with intrahepatic cholestasis.

Bulletin of experimental biology and medicine 20080501

Validation of putative genomic biomarkers of nephrotoxicity in rats.

Toxicology 20080418

Integration of clinical chemistry, expression, and metabolite data leads to better toxicological class separation.

Toxicological sciences : an official journal of the Society of Toxicology 20080401

Protective response of the Ah receptor to ANIT-induced biliary epithelial cell toxicity in see-through medaka.

Toxicological sciences : an official journal of the Society of Toxicology 20080401

[Role of early growth response factor-1 signal pathway in acute intrahepatic cholestatic hepatic injury in rats].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080301

Hepatoprotective effect of Hypericum japonicum extract and its fractions.

Journal of ethnopharmacology 20080227

Seizure susceptibility alteration following reversible cholestasis in mice: Modulation by opioids and nitric oxide.

European journal of pharmacology 20080212

Integrative top-down system metabolic modeling in experimental disease states via data-driven Bayesian methods.

Journal of proteome research 20080201

Non invasive high resolution in vivo imaging of alpha-naphthylisothiocyanate (ANIT) induced hepatobiliary toxicity in STII medaka.

Aquatic toxicology (Amsterdam, Netherlands) 20080120

Piecewise multivariate modelling of sequential metabolic profiling data.

BMC bioinformatics 20080101

A CD133-expressing murine liver oval cell population with bilineage potential.

Stem cells (Dayton, Ohio) 20071001

Acute hepatotoxicity: a predictive model based on focused illumina microarrays.

Toxicological sciences : an official journal of the Society of Toxicology 20070901

Uniform procedure of (1)H NMR analysis of rat urine and toxicometabonomics Part II: comparison of NMR profiles for classification of hepatotoxicity.

Toxicological sciences : an official journal of the Society of Toxicology 20070701

Bone marrow fails to differentiate into liver epithelium during murine development and regeneration.

Hepatology (Baltimore, Md.) 20070501

Determination of phospholipidosis potential based on gene expression analysis in HepG2 cells.

Toxicological sciences : an official journal of the Society of Toxicology 20070301

Melatonin attenuates disruption of serum cholesterol status in rats with a single alpha-naphthylisothiocyanate treatment.

Journal of pineal research 20070301

Ketoprofen glucuronidation and bile excretion in carbon tetrachloride and alpha-naphthylisothiocyanate induced hepatic injury rats.

Toxicology 20070212

Protective effect of glycyrrhizin, glycyrrhetic acid and matrine on acute cholestasis induced by alpha-naphthyl isothiocyanate in rats.

Planta medica 20070201

Protective effect of glycyrrhizin and matrine on acute vanishing bile duct syndrome induced by alpha-naphthylisothiocyanate in rats.

Hepatology research : the official journal of the Japan Society of Hepatology 20070201

Determination and kinetics of producing glucosamine using fungi.

Biotechnology progress 20070101

Saikokeishito Extract Exerts a Therapeutic Effect on alpha-Naphthylisothiocyanate-Induced Liver Injury in Rats through Attenuation of Enhanced Neutrophil Infiltration and Oxidative Stress in the Liver Tissue.

Journal of clinical biochemistry and nutrition 20070101

Investigation of the hepatotoxicity profile of chemical entities using Liverbeads and WIF-B9 in vitro models.

Toxicology in vitro : an international journal published in association with BIBRA 20060901

ANIT toxicity toward mouse hepatocytes in vivo is mediated primarily by neutrophils via CD18.

American journal of physiology. Gastrointestinal and liver physiology 20060801

Heterogeneity of the intrahepatic biliary epithelium.

World journal of gastroenterology 20060614

alpha-Tocopherol protects against alpha-naphthylisothiocyanate-induced hepatotoxicity in rats less effectively than melatonin.

Chemico-biological interactions 20060610

Lack of evidence that bone marrow cells contribute to cholangiocyte repopulation during experimental cholestatic ductal hyperplasia.

Liver international : official journal of the International Association for the Study of the Liver 20060501

Analysis of kanamycin A in human plasma and in oral dosage form by derivatization with 1-naphthyl isothiocyanate and high-performance liquid chromatography.

Journal of separation science 20060301

The potential risks of nanomaterials: a review carried out for ECETOC.

Particle and fibre toxicology 20060101

Characterization of ANIT-induced toxicity using precision-cut rat and dog liver slices cultured in a dynamic organ roller system.

Toxicologic pathology 20060101

Liquid chromatography-mass spectrometric analysis of urinary metabolites and their pattern recognition for the prediction of drug-induced hepatotoxicity.

Chemical research in toxicology 20051201

NMR spectroscopic-based metabonomic investigation on the acute biochemical effects induced by Ce(NO3)3 in rats.

Journal of inorganic biochemistry 20051101

Pharmacokinetics of alpha-naphthyl isothiocyanate in rats.

Journal of pharmaceutical sciences 20051101

Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.

Clinical chemistry 20051001

Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.

Journal of biotechnology 20050929

Chemometric analysis of biofluids following toxicant induced hepatotoxicity: a metabonomic approach to distinguish the effects of 1-naphthylisothiocyanate from its products.

Xenobiotica; the fate of foreign compounds in biological systems 20050801

Comparison of murine cirrhosis models induced by hepatotoxin administration and common bile duct ligation.

World journal of gastroenterology 20050721

Limited protective role of V-PYRRO/NO against cholestasis produced by alpha-naphthylisothiocyanate in mice.

Biochemical pharmacology 20050701

Biliary excretion of taurocholate, organic anions and vinblastine in rats with alpha-naphthylisothiocyanate-induced cholestasis.

Journal of gastroenterology and hepatology 20050701

Effect of alpha-naphthyl isothiocyanate on 2-amino-3-methylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in rats.

International journal of cancer 20050620

Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alpha-naphthylisothiocyanate.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050501

Comparison of metabolic profiles from serum from hepatotoxin-treated rats by nuclear-magnetic-resonance-spectroscopy-based metabonomic analysis.

Analytical biochemistry 20050501

Studies on the acute biochemical effects of La(NO3)3 using 1H NMR spectroscopy of urine combined with pattern recognition.

Journal of inorganic biochemistry 20050201

Identification of 4-methylspinaceamine--a Pictet-Spengler condensation reaction product of histamine with acetaldehyde--in human urine.

Life sciences 20050128

Effects of alpha-naphthyl isothiocyanate and a heterocyclic amine, PhIP, on cytochrome P-450, mutagenic activation of various carcinogens and glucuronidation in rat liver.

Mutagenesis 20050101

In vivo antihepatotoxic effects of Ligularia fischeri var. spiciformis and the identification of the active component, 3,4-dicaffeoylquinic acid.

Journal of medicinal food 20050101

Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury.

American journal of physiology. Gastrointestinal and liver physiology 20040901

Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines.

Experimental biology and medicine (Maywood, N.J.) 20040901

Discriminating different classes of toxicants by transcript profiling.

Environmental health perspectives 20040801

Effects of benzyl-, phenethyl-, and alpha-naphthyl isothiocyanates on P-glycoprotein- and MRP1-mediated transport.

Journal of pharmaceutical sciences 20040701

Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver.

Biochemical pharmacology 20040601

Development of a LC-MS/MS method for the analysis of volatile primary and secondary amines as NIT (naphthylisothiocyanate) derivatives.

Analytical and bioanalytical chemistry 20040201

Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status.

Archives of toxicology 20040201

Effects of feeding and body weight loss on the 1H-NMR-based urine metabolic profiles of male Wistar Han rats: implications for biomarker discovery.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101

[6,8-Dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo[2,3-f]xanthine: a new inductor of the monooxygenase system inhibits experimental intrahepatic cholestasis in rats].

Eksperimental'naia i klinicheskaia farmakologiia 20040101

Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.

The Journal of clinical investigation 20031201

Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes.

Toxicological sciences : an official journal of the Society of Toxicology 20031001

Toward the identification of liver toxicity markers: a proteome study in human cell culture and rats.

Proteomics 20031001

Assessment of hepatocytes and liver slices as in vitro test systems to predict in vivo gene expression.

Toxicological sciences : an official journal of the Society of Toxicology 20030901

Glucocorticoid receptors are downregulated in hepatic T lymphocytes in rats with experimental cholangitis.

Gut 20030901

Histological changes and impairment of liver mitochondrial bioenergetics after long-term treatment with alpha-naphthyl-isothiocyanate (ANIT).

Toxicology 20030828

Glutathione depletion exacerbates methylenedianiline toxicity to biliary epithelial cells and hepatocytes in rats.

Toxicological sciences : an official journal of the Society of Toxicology 20030801

A metabonomic investigation of hepatotoxicity using diffusion-edited 1H NMR spectroscopy of blood serum.

The Analyst 20030701

Determination of alpha-naphthylisothiocyanate and metabolites alpha-naphthylamine and alpha-naphthylisocyanate in rat plasma and urine by high-performance liquid chromatography.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505

Preventive effect of melatonin on the progression of alpha-naphthylisothiocyanate-induced acute liver injury in rats.

Journal of pineal research 20030401

Hepatic artery and portal vein remodeling in rat liver: vascular response to selective cholangiocyte proliferation.

The American journal of pathology 20030401

Cholestasis induced by chronic treatment with alpha-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics.

Archives of toxicology 20030401

An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria.

Archives of toxicology 20030401

Cardiac mitochondrial calcium loading capacity is severely affected after chronic cholestasis in Wistar rats.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20030301

Reduction in cardiac mitochondrial calcium loading capacity is observable during alpha-naphthylisothiocyanate-induced acute cholestasis: a clue for hepatic-derived cardiomyopathies?

Biochimica et biophysica acta 20030120

Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20030101

Cholestasis: human disease and experimental animal models.

Annals of hepatology 20030101

Trace analysis of tobramycin in human plasma by derivatization and high-performance liquid chromatography with ultraviolet detection.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125

Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine.

Pharmaceutical research 20021001

Efficiency of enzyme-inducing agents in rats with intrahepatic cholestasis.

Bulletin of experimental biology and medicine 20020901

Functional heterogeneity of cholangiocytes.

Seminars in liver disease 20020801

NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate.

Biochemical pharmacology 20020701

Improved efficiency of hepatic mitochondrial function in rats with cholestasis induced by an acute dose of alpha-naphthylisothiocyanate.

Toxicology and applied pharmacology 20020701

Experimental colitis attenuates development of toxin-induced cholangitis in rats.

Digestive diseases and sciences 20020601

Disruption of mitochondrial calcium homeostasis after chronic alpha-naphthylisothiocyanate administration: relevance for cholestasis.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020501

Preventive effect of the Taiwan folk medicine Ixeris laevigata var. oldhami on alpha-naphthyl-isothiocyanate and carbon tetrachloride-induced acute liver injury in rats.

Phytotherapy research : PTR 20020301

Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data.

The Analyst 20020201

Alpha-glutathione S-transferase in the assessment of hepatotoxicity--its diagnostic utility in comparison with other recognized markers in the Wistar Han rat.

Toxicologic pathology 20020101

High performance liquid chromatographic determination of glucosamine in rat plasma.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20020101

Prophylactic effect of four prescriptions of traditional Chinese medicine on alpha-naphthylisothiocyanate and carbon tetrachloride induced toxicity in rats.

Acta pharmacologica Sinica 20011201

Effect of melatonin on changes in hepatic antioxidant enzyme activities in rats treated with alpha-naphthylisothiocyanate.

Journal of pineal research 20011101

Role of MRP2 and GSH in intrahepatic cycling of toxins.

Toxicology 20011005

NMR and pattern recognition studies on the time-related metabolic effects of alpha-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach.

Chemical research in toxicology 20011001

Regression of cholangiocyte proliferation after cessation of ANIT feeding is coupled with increased apoptosis.

American journal of physiology. Gastrointestinal and liver physiology 20010701

Quantitative assessment of the rat intrahepatic biliary system by three-dimensional reconstruction.

The American journal of pathology 20010601

[Study on hepatic-protective effect of 'yinzhihuang' granula].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010501

Regulation of cholangiocyte proliferation.

Liver 20010401

Determination of morpholine in air by derivatisation with 1-naphthylisothiocyanate and HPLC analysis.

The Analyst 20010201

Characterization of the protective effects of melatonin and related indoles against alpha-naphthylisothiocyanate-induced liver injury in rats.

Journal of cellular biochemistry 20010101

Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants.

Toxicological sciences : an official journal of the Society of Toxicology 20001001

ANIT-induced disruption of biliary function in rat hepatocyte couplets.

Toxicological sciences : an official journal of the Society of Toxicology 19990201

Cytotoxicity of naphthylisothiocyanates in rat hepatocyte-neutrophil cocultures.

Toxicology letters 19980501

Naphthylisothiocyanate disposition in bile and its relationship to liver glutathione and toxicity.

Biochemical pharmacology 19951026

Leukotrienes and alpha-naphthylisothiocyanate-induced liver injury.

Toxicology 19950626

Cholestatic potentials of alpha-naphthylisothiocyanate (ANIT) and beta-naphthylisothiocyanate (BNIT) in the isolated perfused rat liver.

Biochemical pharmacology 19931203

Lack of benefit of ursodeoxycholic acid in drug-induced cholestasis in the rat.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19920501

Relationship between alpha-naphthylisothiocyanate-induced liver injury and elevations in hepatic non-protein sulfhydryl content.

Biochemical pharmacology 19910822

Increased paracellular permeability in intrahepatic cholestasis induced by carmustine (BCNU) in rats.

Gastroenterology 19910701

Drug-induced intrahepatic cholestasis: characterization of different pathomechanisms.

Archives of toxicology 19870101

Hepatic levels of cytosolic, microsomal and 'mitochondrial' epoxide hydrolases and other drug-metabolizing enzymes after treatment of mice with various xenobiotics and endogenous compounds.

Chemico-biological interactions 19870101

No increase of biliary permeability in ethinylestradiol-treated rats.

Gastroenterology 19831001

Effect of various factors on the induction of liver tumors in animals by quinoline.

Gan 19771201