Home Other Building Blocks 1-Amino-2-hydroxyindane

1-Amino-2-hydroxyindane

CAS No.:
74165-73-4
Catalog Number:
AG003DXI
Molecular Formula:
C9H11NO
Molecular Weight:
149.1897
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$50
- +
5g
95%
In Stock USA
United States
$150
- +
25g
95%
In Stock USA
United States
$600
- +
Product Description
Catalog Number:
AG003DXI
Chemical Name:
1-Amino-2-hydroxyindane
CAS Number:
74165-73-4
Molecular Formula:
C9H11NO
Molecular Weight:
149.1897
MDL Number:
MFCD00053472
IUPAC Name:
1-amino-2,3-dihydro-1H-inden-2-ol
InChI:
InChI=1S/C9H11NO/c10-9-7-4-2-1-3-6(7)5-8(9)11/h1-4,8-9,11H,5,10H2
InChI Key:
LOPKSXMQWBYUOI-UHFFFAOYSA-N
SMILES:
NC1C(O)Cc2c1cccc2
Properties
Complexity:
149  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
149.084g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
149.193g/mol
Monoisotopic Mass:
149.084g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
46.2A^2
Undefined Atom Stereocenter Count:
2  
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2  
Literature
Title Journal
Synthesis and biological evaluation of novel homochiral carbocyclic nucleosides from 1-amino-2-indanols. Bioorganic & medicinal chemistry 20121001
Stereocontrolled synthesis of substituted chiral piperidines via one-pot asymmetric 6π-azaelectrocyclization: asymmetric syntheses of (-)-dendroprimine, (+)-7-epidendroprimine, (+)-5-epidendroprimine, and (+)-5,7-epidendroprimine. The Journal of organic chemistry 20120217
The design and synthesis of novel IBiox N-heterocyclic carbene ligands derived from substituted amino-indanols. Organic & biomolecular chemistry 20120121
The role of weak hydrogen bonds in chiral recognition. Physical chemistry chemical physics : PCCP 20111028
Amino-indanol-catalyzed asymmetric Michael additions of oxindoles to protected 2-amino-1-nitroethenes for the synthesis of 3,3'-disubstituted oxindoles bearing α,β-diamino functionality. The Journal of organic chemistry 20110520
Chiral recognition in jet-cooled complexes of (1R,2S)-(+)-cis-1-amino-2-indanol and methyl lactate: on the importance of the CH...pi interaction. Physical chemistry chemical physics : PCCP 20090921
Glyceraldehyde-3-phosphate dehydrogenase-monoamine oxidase B-mediated cell death-induced by ethanol is prevented by rasagiline and 1-R-aminoindan. Neurotoxicity research 20090801
Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis. Neurotoxicity research 20090401
Kinetic resolution of racemic pyrrolidine-2,5-diones using chiral oxazaborolidine catalysts. Chemical communications (Cambridge, England) 20080521
Indene-based thiazolidinethione chiral auxiliary for propionate and acetate aldol additions. Organic letters 20080221
Differential behavioral syndrome evoked in the rats after multiple doses of SSRI fluoxetine with selective MAO inhibitors rasagiline or selegiline. Journal of neural transmission (Vienna, Austria : 1996) 20080101
The role of CH/pi interaction in the stabilization of less-soluble diastereomeric salt crystals. Chemical record (New York, N.Y.) 20070101
Fluorescence spectroscopy of jet-cooled chiral (+/-)-indan-1-ol and its cluster with (+/-)-methyl- and ethyl-lactate. The Journal of chemical physics 20061107
cis-1-Amino-2-indanol in drug design and applications to asymmetric processes. Chemical reviews 20060701
Synthesis of enantiomerically pure trans-(1R,2R)- and cis-(1S,2R)-1-amino-2-indanol by lipase and omega-transaminase. Biotechnology and bioengineering 20060205
Rational design of CH/pi interaction sites in a basic resolving agent. The Journal of organic chemistry 20041029
Synthetic applicability and in situ recycling of a B-methoxy oxazaborolidine catalyst derived from cis-1-amino-indan-2-ol. Organic letters 20040805
C2-symmetric inhibitors of Plasmodium falciparum plasmepsin II: synthesis and theoretical predictions. Bioorganic & medicinal chemistry 20030815
Improved synthesis of tert-butanesulfinamide suitable for large-scale production. Organic letters 20030417
Measurement of strain-dependent toxicity in the indene bioconversion using multiparameter flow cytometry. Biotechnology and bioengineering 20030220
Engineering an indene bioconversion process for the production of cis-aminoindanol: a model system for the production of chiral synthons. Applied microbiology and biotechnology 20020801
Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay. Biochemistry 20020122
Metabolic engineering of indene bioconversion in Rhodococcus sp. Advances in biochemical engineering/biotechnology 20010101
Properties