Home Other Building Blocks 13-cis-Retinoic acid

13-cis-Retinoic acid

CAS No.:
4759-48-2
Catalog Number:
AG003DVB
Molecular Formula:
C20H28O2
Molecular Weight:
300.4351
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
~75%(HPLC)
In Stock USA
United States
$47
- +
25g
~75%(HPLC)
In Stock USA
United States
$113
- +
100g
~75%(HPLC)
In Stock USA
United States
$294
- +
Product Description
Catalog Number:
AG003DVB
Chemical Name:
13-cis-Retinoic acid
CAS Number:
4759-48-2
Molecular Formula:
C20H28O2
Molecular Weight:
300.4351
MDL Number:
MFCD00079542
IUPAC Name:
(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
InChI:
InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
InChI Key:
SHGAZHPCJJPHSC-XFYACQKRSA-N
SMILES:
C/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C
EC Number:
225-296-0
UNII:
EH28UP18IF
NSC Number:
758156
RTECS Number:
VH6440000
Properties
Complexity:
567  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
4  
Exact Mass:
300.209g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
300.442g/mol
Monoisotopic Mass:
300.209g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
37.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
6.3  
Literature
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The cultivation and identification of tumor stem cells from neuroblastoma derived tumor spheres. Chinese journal of cancer 20101201
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Raldh3 expression in diabetic islets reciprocally regulates secretion of insulin and glucagon from pancreatic islets. Biochemical and biophysical research communications 20101008
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Isotretinoin plus clindamycin seem highly effective against severe erlotinib-induced skin rash in advanced non-small cell lung cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101001
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Isotretinoin-induced effects of mast cells on wound healing. Journal of drugs in dermatology : JDD 20101001
Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. The New England journal of medicine 20100930
Antiproliferative effect of 13-cis-retinoic acid is associated with granulocyte differentiation and decrease in cyclin B1 and Bcl-2 protein levels in G0/G1 arrested HL-60 cells. Pathology oncology research : POR 20100901
Isotretinoin use and the risk of inflammatory bowel disease: a case-control study. The American journal of gastroenterology 20100901
Development of canal cholesteatoma in a patient with prenatal isotretinoin exposure. International journal of pediatric otorhinolaryngology 20100901
Palliative treatment of paraneoplastic acanthosis nigricans and oral florid papillomatosis with retinoids. Journal of drugs in dermatology : JDD 20100901
Acne - best practice management. Australian family physician 20100901
Acute generalized exanthematous pustulosis induced by isotretinoin. International journal of dermatology 20100901
The effect of isotretinoin treatment on plasma homocysteine levels in acne vulgaris. Clinical and experimental dermatology 20100801
Relevance of nonsynonymous CYP2C8 polymorphisms to 13-cis retinoic acid and paclitaxel hydroxylation. Drug metabolism and disposition: the biological fate of chemicals 20100801
Isotretinoin exposure during pregnancy: assessment of spontaneous reports in France. Drug safety 20100801
Facial porokeratosis: A series of six patients. The Australasian journal of dermatology 20100801
Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans. Drug metabolism and disposition: the biological fate of chemicals 20100701
Systemic isotretinoin in the treatment of rosacea - doxycycline- and placebo-controlled, randomized clinical study. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20100701
Treatment of extrafacial rosacea with low-dose isotretinoin. Acta dermato-venereologica 20100701
Onset of Kleine-Levin Syndrome in association with isotretinoin treatment. Acta paediatrica (Oslo, Norway : 1992) 20100601
Is nuclear deficiency of FoxO1 due to increased growth factor/PI3K/Akt-signalling in acne vulgaris reversed by isotretinoin treatment? The British journal of dermatology 20100601
Mortality in the randomized, controlled lung intergroup trial of isotretinoin. Cancer prevention research (Philadelphia, Pa.) 20100601
Regeneration of the gut requires retinoic acid in the budding ascidian Polyandrocarpa misakiensis. Development, growth & differentiation 20100601
Severe ulcerated 'bodybuilding acne' caused by anabolic steroid use and exacerbated by isotretinoin. International wound journal 20100601
Isotretinoin as monotherapy for sebaceous hyperplasia. Journal of drugs in dermatology : JDD 20100601
Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. 2010. The British journal of dermatology 20100601
A novel therapeutic combination for neuroblastoma: the vascular endothelial growth factor receptor/epidermal growth factor receptor/rearranged during transfection inhibitor vandetanib with 13-cis-retinoic acid. Cancer 20100515
Sacroiliitis and severe disability due to isotretinoin therapy. Rheumatology international 20100501
Psychiatric reactions to isotretinoin in patients with bipolar disorder. Journal of affective disorders 20100501
High-dose treatment with vitamin A analogues and risk of fractures. Archives of dermatology 20100501
Inflammatory information. Cutis 20100501
Short-term isotretinoin treatment decreases insulin-like growth factor-1 and insulin-like growth factor binding protein-3 levels: does isotretinoin affect growth hormone physiology? The British journal of dermatology 20100401
Dermabrasion for acne scars during treatment with oral isotretinoin. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20100401
Isotretinoin use and compliance with the Dutch Pregnancy Prevention Programme: a retrospective cohort study in females of reproductive age using pharmacy dispensing data. Drug safety 20100401
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Combinational treatment with retinoic acid derivatives in non-small cell lung carcinoma in vitro. Journal of Korean medical science 20070901
Isotretinoin as a diagnostic tool for localization of thyroid tissue in a thyroid cancer patient: a case report. Thyroid : official journal of the American Thyroid Association 20070901
Biopharmaceutics of 13-cis-retinoic acid (isotretinoin) formulated with modified beta-cyclodextrins. International journal of pharmaceutics 20070816
Sequence-dependent antitumor effects of differentiation agents in combination with cell cycle-dependent cytotoxic drugs. Cancer chemotherapy and pharmacology 20070801
Body dysmorphic disorder symptoms among patients with acne vulgaris. Journal of the American Academy of Dermatology 20070801
Isotretinoin and night vision. The British journal of ophthalmology 20070801
Valproic acid combined with 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 in the treatment of patients with myelodysplastic syndromes. Haematologica 20070801
Acute myopia while on oral isotretinoin treatment. Journal of the European Academy of Dermatology and Venereology : JEADV 20070801
Atrial tachycardia associated with isotretinoin use. Archives of dermatology 20070801
What's your assessment? Acne conglobata (AC). Dermatology nursing 20070801
The ache of isotretinoin. Cutis 20070801
[Therapy of severe cetuximab-induced acneiform eruptions with oral retinoid, topical antibiotic and topical corticosteroid]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20070701
Isotretinoin and inflammatory bowel disease. The American journal of gastroenterology 20070701
Responses to open peer commentaries on 'Physicians' silent decisions: because patient autonomy doesn't always come first'. The American journal of bioethics : AJOB 20070701
Physicians' silent decisions: because patient autonomy does not always come first. The American journal of bioethics : AJOB 20070701
Silence is not always golden in medical decision-making. The American journal of bioethics : AJOB 20070701
Silent decisions or veiled paternalism? Physicians are not experts in judging character. The American journal of bioethics : AJOB 20070701
Isotretinoin as a treatment for axillary granular parakeratosis. Cutis 20070701
Ethanol induces cholesterol efflux and up-regulates ATP-binding cassette cholesterol transporters in fetal astrocytes. The Journal of biological chemistry 20070629
Molecular targeting of retinoic acid metabolism in neuroblastoma: the role of the CYP26 inhibitor R116010 in vitro and in vivo. British journal of cancer 20070604
Cerebral ischemia probably related to isotretinoin. The Annals of pharmacotherapy 20070601
13-cis-Retinoic acid therapy induces insulin resistance, regulates inflammatory parameters, and paradoxically increases serum adiponectin concentration. Metabolism: clinical and experimental 20070601
Isotretinoin and inflammatory bowel disease. The American journal of gastroenterology 20070601
Isotretinoin: stroke and myocardial infarction? Prescrire international 20070601
Monitoring people treated with isotretinoin for depression. Psychological reports 20070601
Randomized trial of adjuvant 13-cis-retinoic acid and interferon alfa for patients with aggressive skin squamous cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070520
Phase II study of interleukin-2 and 13-cis-retinoic acid as maintenance therapy in metastatic colorectal cancer. Cancer immunology, immunotherapy : CII 20070501
A case of generalized granuloma annulare with myelodysplastic syndrome: successful treatment with systemic isotretinoin and topical pimecrolimus 1% cream combination. Journal of the European Academy of Dermatology and Venereology : JEADV 20070501
Isotretinoin, depression and suicide ideation in an adolescent boy. Pharmacopsychiatry 20070501
[Back pain and acne conglobata: SAPHO syndrome]. Praxis 20070411
Favorable histology, MYCN-amplified 4S neonatal neuroblastoma. Pediatric blood & cancer 20070401
Induction of cell cycle arrest and apoptosis by a combined treatment with 13-cis-retinoic acid, interferon-alpha2a, and alpha-tocopherol in squamous cell carcinoma of the head and neck. Head & neck 20070401
Acute depression caused by isotretinoin: does it exist? Journal of the European Academy of Dermatology and Venereology : JEADV 20070401
Menstrual irregularity during isotretinoin treatment. Journal of the European Academy of Dermatology and Venereology : JEADV 20070401
Pharmacologic modulation of sebaceous gland activity: mechanisms and clinical applications. Dermatologic clinics 20070401
On-line concentration and determination of all-trans- and 13-cis- retinoic acids in rabbit serum by application of sweeping technique in micellar electrokinetic chromatography. Journal of chromatography. A 20070330
Acneiform eruptions associated with epidermal growth factor receptor-targeted chemotherapy. Journal of the American Academy of Dermatology 20070301
Epidermal growth factor receptor inhibitors: a new era of drug reactions in a new era of cancer therapy. Journal of the American Academy of Dermatology 20070301
Effects of cisplatin, alpha-interferon, and 13-cis retinoic acid on the expression of Fas (CD95), intercellular adhesion molecule-1 (ICAM-1), and epidermal growth factor receptor (EGFR) in oral cancer cell lines. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20070301
Effective treatment of papular acantholytic dyskeratosis with oral isotretinoin. Journal of the European Academy of Dermatology and Venereology : JEADV 20070301
Nudulo-cystic eruption with musculoskeletal pain. The Journal of family practice 20070301
13-cis-Retinoic acid in combination with gemcitabine in the treatment of locally advanced and metastatic pancreatic cancer--report of a pilot phase II study. Clinical oncology (Royal College of Radiologists (Great Britain)) 20070301
A rapid HPLC method for simultaneous determination of tretinoin and isotretinoin in dermatological formulations. Journal of pharmaceutical and biomedical analysis 20070219
Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma - a study of the United Kingdom Children's Cancer Study Group. British journal of cancer 20070212
Isotretinoin, pregnancies, abortions and birth defects: a population-based perspective. British journal of clinical pharmacology 20070201
Isotretinoin-induced pleuritic chest pain. The British journal of dermatology 20070201
All-trans-retinoic acid and 13-cis-retinoic acid: pharmacokinetics and biological activity in different cell culture models of human keratinocytes. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070201
[Sweet's syndrome complicating isotretinoin therapy in acne]. Annales de dermatologie et de venereologie 20070201
Keratosis follicularis (Darier-White disease), with an unusual palmoplantar keratoderma. Dermatology online journal 20070127
Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery. International journal of pharmaceutics 20070110
Effects of oral isotretinoin therapy on peripheral nerve functions: a preliminary study. Clinical and experimental dermatology 20070101
Oral Accutane (13-cis-retinoic acid) has no effects on spatial learning and memory in male and female Sprague-Dawley rats. Neurotoxicology and teratology 20070101
Can we ensure the safe use of known human teratogens?: The iPLEDGE test case. Drug safety 20070101
Multiple keratoacanthomas in a young woman: report of a case emphasizing medical management and a review of the spectrum of multiple keratoacanthomas. International journal of dermatology 20070101
Antitumor effect of the histone deacetylase inhibitor LAQ824 in combination with 13-cis-retinoic acid in human malignant melanoma. Molecular cancer therapeutics 20070101
Perifolliculitis capitis abscedens et suffodiens in an 18-year-old Aboriginal Canadian patient: case report and review of the literature. Journal of cutaneous medicine and surgery 20070101
The cost of clear skin: balancing the social and safety costs of iPLEDGE with the efficacy of Accutane (isotretinoin). Seton Hall law review 20070101
Patient receipt and understanding of written information provided with isotretinoin and estrogen prescriptions. Journal of general internal medicine 20070101
Cytodifferentiation by retinoids, a novel therapeutic option in oncology: rational combinations with other therapeutic agents. Vitamins and hormones 20070101
Reduced salivary flow induced by systemic isotretinoin may lead to dental decay. A prospective clinical study. Dermatology (Basel, Switzerland) 20070101
Position statement for isotretinoin. Journal of cutaneous medicine and surgery 20070101
Antiandrogenic effect of isotretinoin: is the retina involved in mechanism of action? Medical hypotheses 20070101
Clinical and microbiological comparisons of isotretinoin vs. tetracycline in acne vulgaris. Acta dermato-venereologica 20070101
Safe usage of isotretinoin in a woman with latent acute intermittent porphyria. Acta dermato-venereologica 20070101
No association found between patients receiving isotretinoin for acne and the development of depression in a Canadian prospective cohort. The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20070101
Pharmacokinetics and pharmacogenetics of 13-cis-retinoic acid in the treatment of neuroblastoma. Therapie 20070101
Effect of 13-cis-retinoic acid on the genetic expression profile of human umbilical vein endothelial cells (HUVECs) determined by microarray. Clinical chemistry and laboratory medicine 20070101
The need for restricted prescription of retinoic acid derivative isotretinoin to prevent retinoid teratogenicity. Preventive medicine 20070101
[Toxic effects of medications on the cornea]. Bulletin de la Societe belge d'ophtalmologie 20070101
Isotretinoin-induced agranulocytosis. Pediatric dermatology 20070101
Moving toward bioadjuvant approaches to head and neck cancer prevention. International journal of radiation oncology, biology, physics 20070101
SEM analysis of oral lichen planus before and after treatment with 13 cis-retinoic acid. International journal of immunopathology and pharmacology 20070101
Age-related change in the retinoid X receptor beta gene expression in peripheral blood mononuclear cells of healthy volunteers: effect of 13-cis retinoic acid supplementation. Mechanisms of ageing and development 20070101
Oral treatment with ACCUTANE does not increase measures of anhedonia or depression in rats. Neurotoxicology and teratology 20070101
Angiolymphoid hyperplasia with eosinophilia treated with isotretinoin. European journal of dermatology : EJD 20070101
Childhood generalized pustular psoriasis: successful treatment with isotretinoin. Pediatric dermatology 20070101
[The state of keratinocytes of interfollicular epidermis after 13-cis-retinoic acid application (immunocytochemical analysis)]. Morfologiia (Saint Petersburg, Russia) 20070101
13-cis-Retinoic acid (isotretinoin) unmasking of clinical polycystic ovary syndrome. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20070101
13 Cis-retinoic acid mediates apoptosis in Dalton's lymphoma ascites cells by regulating gene expression. Journal of basic and clinical physiology and pharmacology 20070101
[Roaccutane and inflammatory bowel disease]. Lakartidningen 20061213
Joint effect of mutagen sensitivity and insulin-like growth factors in predicting the risk of developing secondary primary tumors and tumor recurrence in patients with head and neck cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20061201
Oral treatment with retinoic acid decreases bone mass in rats. Comparative medicine 20061201
[Panic attacks in a patient treated with isotretinoin for acne. Report of one case]. Revista medica de Chile 20061201
The results and side effects of systemic isotretinoin treatment in 100 patients with acne vulgaris. Dermatology nursing 20061201
Incidence of depression related to isotretinoin treatment in 100 acne vulgaris patients. Psychological reports 20061201
Folliculitis decalvans of the scalp: response to triple therapy with isotretinoin, clindamycin, and prednisolone. Acta dermatovenerologica Alpina, Pannonica, et Adriatica 20061201
Cytotoxic effect induced by retinoic acid loaded into galactosyl-sphingosine containing liposomes on human hepatoma cell lines. International journal of pharmaceutics 20061115
Pyoderma gangrenosum associated with isotretinoin therapy. Journal of the American Academy of Dermatology 20061101
The effectiveness of intermittent isotretinoin treatment in mild or moderate acne. Journal of the European Academy of Dermatology and Venereology : JEADV 20061101
A rare side-effect of systemic isotretinoin treatment: hoarseness. Journal of the European Academy of Dermatology and Venereology : JEADV 20061101
Anal fissure, rectal bleeding and proctitis as complications of systemic isotretinoin therapy: report of two cases. Journal of the European Academy of Dermatology and Venereology : JEADV 20061101
Feasibility of retinoids for the treatment of emphysema study. Chest 20061101
What is the best approach to reducing birth defects associated with isotretinoin? PLoS medicine 20061101
[Rosacea fulminans, pyostomatitis and pyovulvitis in Crohn's disease: dapsone as key factor in combination therapy]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20061001
13-cis Retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytes. The Journal of investigative dermatology 20061001
Isotretinoin revisited: pluripotent effects on human sebaceous gland cells. The Journal of investigative dermatology 20061001
Current concepts in acne management. Adolescent medicine clinics 20061001
Oral isotretinoin for acne, adjusting treatment according to patient's response. Journal of drugs in dermatology : JDD 20061001
Schools of pharmacology: retinoid update. Journal of drugs in dermatology : JDD 20061001
Efficacy of isotretinoin in pityriasis rubra pilaris: unapproved use. International journal of dermatology 20061001
Chronic administration of 13-cis-retinoic acid increases depression-related behavior in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060901
Peroxisome proliferator-activated receptors increase human sebum production. The Journal of investigative dermatology 20060901
Ensuring the safe and effective use of medications during pregnancy: planning and prevention through preconception care. Maternal and child health journal 20060901
The British Association of Dermatologists isotretinoin questionnaire for patients: a useful clinical tool. Clinical and experimental dermatology 20060901
A risk management program aimed at preventing fetal exposure to isotretinoin: retrospective cohort study. Journal of the American Academy of Dermatology 20060901
The effects of isotretinoin treatment on bone mineral density in patients with nodulocystic acne. Journal of the European Academy of Dermatology and Venereology : JEADV 20060901
Managing acne vulgaris effectively. Australian family physician 20060901
Adverse drug reactions. Southern medical journal 20060901
An adolescent with abdominal pain taking isotretinoin for severe acne. Southern medical journal 20060901
Acne fulminans: a case report. South Dakota medicine : the journal of the South Dakota State Medical Association 20060901
Interleukin-2/interferon-alpha2a/13-retinoic acid-based chemoimmunotherapy in advanced renal cell carcinoma: results of a prospectively randomised trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN). British journal of cancer 20060821
Increased use of mental health services related to isotretinoin treatment: a 5-year analysis. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060801
Does use of isotretinoin rule out a career in flying? The British journal of ophthalmology 20060801
Patterns and utilization of isotretinoin for acne from 1984 to 2003: is there need for concern? European journal of clinical pharmacology 20060801
Wolf's isotopic response: rosacea appearing at the site of healed herpes zoster. The Australasian journal of dermatology 20060801
A review of the European Directive for prescribing systemic isotretinoin for acne vulgaris. Journal of the European Academy of Dermatology and Venereology : JEADV 20060801
A population-based analysis of laboratory abnormalities during isotretinoin therapy for acne vulgaris. Archives of dermatology 20060801
The Smart Card: an alternative solution for the iPledge program. Archives of dermatology 20060801
A novel cytochrome P450, zebrafish Cyp26D1, is involved in metabolism of all-trans retinoic acid. Molecular endocrinology (Baltimore, Md.) 20060701
Retinoids activate the RXR/SXR-mediated pathway and induce the endogenous CYP3A4 activity in Huh7 human hepatoma cells. Toxicological sciences : an official journal of the Society of Toxicology 20060701
Possible isotretinoin-induced keloids in a patient with Behçet's disease. Clinical and experimental dermatology 20060701
Vitamin B12 and folate deficiency anaemia associated with isotretinoin treatment for acne. Clinical and experimental dermatology 20060701
Vaginal bleeding after initiation of isotretinoin in a female-to-male transsexual on testosterone. The British journal of dermatology 20060701
Isotretinoin in treatment of acne: its efficacy, side effects, and recurrence rate of disease. Archives of Iranian medicine 20060701
Isotretinoin and the controversy of psychiatric adverse effects. International journal of dermatology 20060701
Possible association between isotretinoin and inflammatory bowel disease. The American journal of gastroenterology 20060701
[Mechanism of receptor for retinoids inducing apoptosis of human melanoma cell line A375]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060701
Evaluation of glutathione S-transferase polymorphisms and mutagen sensitivity as risk factors for the development of second primary tumors in patients previously diagnosed with early-stage head and neck cancer. Cancer 20060615
Accutane registry compulsory in US, but not Canada. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060606
Steady state pharmacokinetics of oral treatment with 13-cis-retinoic acid or all-trans-retinoic acid in male and female adult rats. Basic & clinical pharmacology & toxicology 20060601
Light-assisted hair removal in patients undergoing isotretinoin therapy. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20060601
Isotretinoin--unapproved indications/uses and dosage: a physician's reference. International journal of dermatology 20060601
Acne vulgaris. Clinical evidence 20060601
Combination chemotherapy with 13-cis-retinoic acid and celecoxib in the treatment of glioblastoma multiforme. Journal of neuro-oncology 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Rhinophyma in an adolescent. Journal of the European Academy of Dermatology and Venereology : JEADV 20060501
Facial edema induced by isotretinoin use: a case and a review of the side effects of isotretinoin. Journal of drugs in dermatology : JDD 20060501
Epidermal effects of tretinoin and isotretinoin: influence of isomerism. Die Pharmazie 20060501
A pox on your practice. iPLEDGE program scars dermatologists. Texas medicine 20060501
The retinoic acid paradox in cancer chemoprevention. Journal of the National Cancer Institute 20060405
Randomized phase III trial of low-dose isotretinoin for prevention of second primary tumors in stage I and II head and neck cancer patients. Journal of the National Cancer Institute 20060405
Low-dose isotretinoin in the treatment of acne vulgaris. Journal of the American Academy of Dermatology 20060401
Acute hip monoarthritis in a patient treated with isotretinoin. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20060401
iPLEDGE: protecting patients or prohibiting access to care? Dermatology nursing 20060401
Collagenous colitis: possible link with isotretinoin. European annals of allergy and clinical immunology 20060401
Pregnancy prevention among women taking isotretinoin: failure to comply with the recommendations. Canadian family physician Medecin de famille canadien 20060310
Effects of isotretinoin on the metabolism of triglyceride-rich lipoproteins and on the lipid profile in patients with acne. Archives of dermatological research 20060301
Epitheliotropic cutaneous lymphoma (mycosis fungoides) in a dog. Journal of veterinary science 20060301
One-year results of a pilot study using oral 13-cis retinoic acid as a treatment for subfoveal predominantly occult choroidal neovascularization in patients with age-related macular degeneration. Retina (Philadelphia, Pa.) 20060301
Acne: improving skin and self-esteem. Pediatric annals 20060301
Pharmaceutical quality of generic isotretinoin products, compared with Roaccutane. Current medical research and opinion 20060301
Evaluation of the clinical and histological effectiveness of isotretinoin in the therapy of oral leukoplakia: ten years of experience: is management still up to date and effective? Methods and findings in experimental and clinical pharmacology 20060301
Nonclassical action of retinoic acid on the activation of the cAMP response element-binding protein in normal human bronchial epithelial cells. Molecular biology of the cell 20060201
Paradoxical rise in serum adiponectin concentration in the face of acid-induced insulin resistance 13-cis-retinoic. Diabetologia 20060201
Folliculitis spinulosa decalvans: failure to respond to oral isotretinoin. Journal of the European Academy of Dermatology and Venereology : JEADV 20060201
Recovery of anaerobic bacteria from a case of dissecting cellulitis. International journal of dermatology 20060201
Isotretinoin-induced inflammatory bowel disease. The Netherlands journal of medicine 20060201
Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation. Biochemistry 20060124
[From the Cochrane Library: Improvement of photodamaged skin with retinoid creams and not with other local treatments]. Nederlands tijdschrift voor geneeskunde 20060121
A randomized trial assessing the effectiveness of different concentrations of isotretinoin in the management of lichen planus. International journal of oral and maxillofacial surgery 20060101
Multicenter phase 2 study of interleukin-2 and 13-cis retinoic acid as maintenance therapy in advanced non-small-cell lung cancer. Journal of immunotherapy (Hagerstown, Md. : 1997) 20060101
The importance of screening for laser-assisted in situ keratomileusis operation (LASIK) before prescribing isotretinoin. Journal of the American Academy of Dermatology 20060101
Recurrent herpes labialis during isotretinoin therapy: is there a role for photosensitivity? Journal of the European Academy of Dermatology and Venereology : JEADV 20060101
Generalized granuloma annulare in a patient with type II diabetes mellitus: successful treatment with isotretinoin. Journal of the European Academy of Dermatology and Venereology : JEADV 20060101
Angioedema and urticaria due to isotretinoin therapy. Journal of the European Academy of Dermatology and Venereology : JEADV 20060101
Short-term oral isotretinoin therapy does not cause clinical or subclinical peripheral neuropathy. The Journal of dermatological treatment 20060101
Oral therapy for rosacea. Journal of drugs in dermatology : JDD 20060101
Tinea versicolor clearance with oral isotretinoin therapy. Journal of drugs in dermatology : JDD 20060101
The truth behind this undeniable efficacy--recurrence rates and relapse risk factors of acne treatment with oral isotretinoin. Dermatology (Basel, Switzerland) 20060101
Prospective study of risk factors of relapse after treatment of acne with oral isotretinoin. Dermatology (Basel, Switzerland) 20060101
Risk. Pennsylvania dental journal 20060101
Acceleration of lung maturation in a human fetus following maternal isotretinoin intake. Biology of the neonate 20060101
[Recurrence in patients diagnosed with acne treated by isotretinoin and other methods]. Wiadomosci lekarskie (Warsaw, Poland : 1960) 20060101
Erythrokeratodermia variabilis with adult onset: report of a sporadic case unresponsive to systemic retinoids. The Journal of dermatological treatment 20060101
In vivo porphyrin production by P. acnes in untreated acne patients and its modulation by acne treatment. Acta dermato-venereologica 20060101
Ulcerative colitis probably associated with isotretinoin. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20060101
Improvement of cystic fibrosis during treatment with isotretinoin. Skinmed 20060101
Is it necessary to have routine blood tests in patients treated with isotretinoin? The Journal of dermatological treatment 20060101
Coping with the isotretinoin registry. Dermatologic therapy 20060101
[Application of 13-cis-retinoic acid in patients with 131I scintigraphically-negative metastases of differentiated thyroid carcinoma]. Endokrynologia Polska 20060101
Acute generalized facial erythema and swelling associated with oral isotretinoin in a child. Pediatric dermatology 20060101
Angiolymphoid hyperplasia with eosinophilia: efficacy of isotretinoin? Head & face medicine 20060101
Differential regulation of Toll-like receptor and CD14 pathways by retinoids and corticosteroids in human sebocytes. Dermatology (Basel, Switzerland) 20060101
[Dermatology under threat]. Annales de dermatologie et de venereologie 20060101
Cyclic adenosine monophosphate-dependent cell type-specific modulation of mitogenic signaling by retinoids in normal and neoplastic lung cells. Cancer detection and prevention 20060101
An expert view on the treatment of acne with systemic antibiotics and/or oral isotretinoin in the light of the new European recommendations. European journal of dermatology : EJD 20060101
Prurigo pigmentosa successfully treated with low-dose isotretinoin. Dermatology (Basel, Switzerland) 20060101
Beneficial effect of a moisturizing cream as adjunctive treatment to oral isotretinoin or topical tretinoin in the management of acne. Journal of drugs in dermatology : JDD 20060101
[Chief teratogenic factors in facial abnormalities]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101
Communication development of a young child with foetal retinoid syndrome: a seven-year follow-up study. The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings 20060101
AT1 receptor and ACE mRNA are increased in chemically induced carcinoma of rat mammary gland. Molecular and cellular endocrinology 20051201
Building upon the standard of care in adjuvant therapy of high-risk melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051201
Prospective, randomized, multicenter, double-blind placebo-controlled trial comparing adjuvant interferon alfa and isotretinoin with interferon alfa alone in stage IIA and IIB melanoma: European Cooperative Adjuvant Melanoma Treatment Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051201
All-trans-retinoic acid accelerates the differentiation of human B lymphocytes maturing into plasma cells. International immunopharmacology 20051201
Retinoic acid is a potential negative regulator for differentiation of human periodontal ligament cells. Journal of periodontal research 20051201
Efficacy of oral isotretinoin in the control of skin and nasal colonization by antibiotic-resistant propionibacteria in patients with acne. The British journal of dermatology 20051201
Retinoic acid induces VEGF gene expression in human retinal pigment epithelial cells (ARPE-19). Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20051201
Development of severe thyroid-associated ophthalmopathy in a patient with disseminated thyroid cancer treated with recombinant human thyrotropin/radioiodine and retinoic acid. Thyroid : official journal of the American Thyroid Association 20051201
Profile of acne patients in the Philippines requiring a second course of oral isotretinoin. International journal of dermatology 20051201
iPLEDGE allegiance. Cutis 20051201
[Ulcerative colitis probably induced by isotretinoin]. Gastroenterologie clinique et biologique 20051201
Wrinkles. Clinical evidence 20051201
Apoptotic events induced by naturally occurring retinoids ATRA and 13-cis retinoic acid on human hepatoma cell lines Hep3B and HepG2. Cancer letters 20051118
Actinic folliculitis. Clinical and experimental dermatology 20051101
Keratosis follicularis spinulosa decalvans and acne keloidalis nuchae. The Australasian journal of dermatology 20051101
A survey of pregnant women using isotretinoin. Birth defects research. Part A, Clinical and molecular teratology 20051101
Erythematous plaques on the flexural surfaces. Archives of dermatology 20051101
Isotretinoin-related optic disc swelling. British journal of hospital medicine (London, England : 2005) 20051101
Acne guideline 2005 update. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20051101
Chronic oral treatment with 13-cis-retinoic acid (isotretinoin) or all-trans-retinoic acid does not alter depression-like behaviors in rats. Toxicological sciences : an official journal of the Society of Toxicology 20051001
Acne, depression, and suicide. Dermatologic clinics 20051001
Interleukin-2 and 13-cis retinoic acid as maintenance therapy in advanced ovarian cancer. International journal of oncology 20051001
Successful treatment with oral isotretinoin of acneiform skin lesions associated with cetuximab therapy. The British journal of dermatology 20051001
Matrix metalloproteinases of epithelial origin in facial sebum of patients with acne and their regulation by isotretinoin. The Journal of investigative dermatology 20051001
Regulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cells. Leukemia & lymphoma 20051001
Isotretinoin in the treatment of multiple benign pilomatrixomas in a mixed-breed dog. Veterinary dermatology 20051001
FDA approves mandatory risk management program for isotretinoin. Dermatology nursing 20051001
Questions & answers. Does the acne drug, isotretinoin (Accutane), cause depression and suicide, or are the psychiatric risk exaggerated? The Harvard mental health letter 20051001
Adult acne. Troublesome, but treatable. Mayo Clinic health letter (English ed.) 20051001
Mechanism of retinoid receptors in inhibiting proliferation and inducing apoptosis of human melanoma cell line A375. Chinese medical journal 20050905
Pledging for accutane. U.S. news & world report 20050905
Changes in isotretinoin prescribing before and after implementation of the System to Manage Accutane Related Teratogenicity (SMART) risk management program. Pharmacoepidemiology and drug safety 20050901
Acquired port wine stain following oral isotretinoin. Clinical and experimental dermatology 20050901
Isotretinoin-induced elkonyxis. The British journal of dermatology 20050901
Isotretinoin prescribing: finding a balance between benefit and risk. Pharmacoepidemiology and drug safety 20050901
Patients' perceptions of isotretinoin, depression and suicide--a qualitative study. Australian family physician 20050901
Four weeks of oral isotretinoin treatment causes few signs of general toxicity in male and female Sprague-Dawley rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050801
[Receptor-related mechanism of proliferation inhibilion and apoptosis induetion of human tongue squamous cell line Tca8113 by retinoids]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050801
Combination therapy is the standard of care. Cutis 20050801
Pimple positives. Cutis 20050801
Development of a gas chromatography method for the determination of isotretinoin and its degradation products in pharmaceuticals. Journal of pharmaceutical and biomedical analysis 20050715
Isotretinoin does have an adverse effect on bone mineral density. Journal of the American Academy of Dermatology 20050701
13-cis retinoic acid inhibits development and progression of chronic allograft nephropathy. The American journal of pathology 20050701
Retinoic acid and its 4-oxo metabolites are functionally active in human skin cells in vitro. The Journal of investigative dermatology 20050701
Vesiculous prurigo pigmentosa in a 13-year-old girl: good response to isotretinoin. Journal of the European Academy of Dermatology and Venereology : JEADV 20050701
Managing adolescent acne: a guide for pediatricians. Pediatrics in review 20050701
Erythematous and hypopigmented patches on the face. Archives of dermatology 20050701
Randomized phase II/III trial of interferon Alfa-2a with and without 13-cis-retinoic acid in patients with progressive metastatic renal cell Carcinoma: the European Organisation for Research and Treatment of Cancer Genito-Urinary Tract Cancer Group (EORTC 30951). Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050620
In vivo imaging of retinoic acid receptor beta2 transcriptional activation by the histone deacetylase inhibitor MS-275 in retinoid-resistant prostate cancer cells. The Prostate 20050615
Introduction: welcome to the next generation of acne research. Seminars in cutaneous medicine and surgery 20050601
Depression and suicidal behavior in acne patients treated with isotretinoin: a systematic review. Seminars in cutaneous medicine and surgery 20050601
Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3, 4-dihydronaphthalen-1(2H)-one on all-trans and 13-cis-retinoic acid levels in plasma quantified by high perfomance liquid chromatography coupled to tandem mass spectrometry. Journal of enzyme inhibition and medicinal chemistry 20050601
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Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by phase solubility, photostability, physicochemical and computational analysis. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050501
Acute depression from isotretinoin. Another case. Journal of the European Academy of Dermatology and Venereology : JEADV 20050501
Dermatoses of pregnancy update. Journal of the American Academy of Dermatology 20050501
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A phase II study of concurrent temozolomide and cis-retinoic acid with radiation for adult patients with newly diagnosed supratentorial glioblastoma. International journal of radiation oncology, biology, physics 20050401
Isotretinoin (13-cis-retinoic acid) associated atrial tachycardia. Pacing and clinical electrophysiology : PACE 20050401
Phase 2 bioadjuvant study of interferon alfa-2a, isotretinoin, and vitamin E in locally advanced squamous cell carcinoma of the head and neck: long-term follow-up. Archives of otolaryngology--head & neck surgery 20050401
Congenital oculomotor nerve synkinesis associated with fetal retinoid syndrome. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20050401
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Treatment of photoaged skin with a cream containing 0.05% isotretinoin and sunscreens. The Journal of dermatological treatment 20050401
The detection of differentiation-inducing chemicals by using green fluorescent protein expression in genetically engineered teratocarcinoma cells. Alternatives to laboratory animals : ATLA 20050401
Expression of gastrointestinal glutathione peroxidase is inversely correlated to the presence of hepatitis C virus subgenomic RNA in human liver cells. The Journal of biological chemistry 20050311
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Diode laser hair removal and isotretinoin therapy. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20050301
Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells. British journal of cancer 20050227
Retinoids and pulmonary hypertension. Circulation 20050215
Determination of plasma and brain levels of isotretinoin in mice following single oral dose by high-performance liquid chromatography. Journal of pharmaceutical and biomedical analysis 20050207
Flushing and papules in a middle-aged woman. Obstetrics and gynecology 20050201
Acne fulminans. International journal of dermatology 20050201
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A 20-year-old basal cell carcinoma. Plastic and reconstructive surgery 20050201
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A prospective study of the responsiveness of depression and suicidal ideation in acne patients to different phases of isotretinoin therapy. European journal of dermatology : EJD 20050101
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[Patient with ileitis associated to...]. Acta gastroenterologica Latinoamericana 20050101
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A phase II study using retinoids as redifferentiation agents to increase iodine uptake in metastatic thyroid cancer. Clinical oncology (Royal College of Radiologists (Great Britain)) 20041201
Follicular mucinosis responding to isotretinoin treatment. The Journal of dermatological treatment 20041201
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Oral isotretinoin and haemophilia A. Journal of the European Academy of Dermatology and Venereology : JEADV 20041101
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Effect of a single course of isotretinoin therapy on bone mineral density in adolescent patients with severe, recalcitrant, nodular acne. Journal of the American Academy of Dermatology 20041101
[Confluent and reticulated papillomatosis. Gougerot-Carteaud disease]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20041001
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Diode laser hair removal in patients undergoing isotretinoin therapy. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20040901
A case of condyloma acuminatum treated successfully with low-dose isotretinoin and interferon. International journal of clinical practice 20040901
Treatment of acne vulgaris. JAMA 20040811
Interferon-alpha-2a with or without 13-cis retinoic acid in patients with progressive, measurable metastatic renal cell carcinoma. Cancer 20040801
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Acne vulgaris: myths and misconceptions among patients and family physicians. Patient education and counseling 20040701
13-cis-retinoic acid in the treatment of recurrent glioblastoma multiforme. Neuro-oncology 20040701
[Treatment of high-risk neuroblastoma with intensive chemotherapy, autologous peripheral blood stem cell transplantation, and 13-cis-retinoic acid]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20040701
The moral of the isotretinoin depression story. The Journal of dermatological treatment 20040701
Depression is not common in isotretinoin-treated acne patients. The Journal of dermatological treatment 20040701
Analysis of pilot and early phase studies with small sample sizes. Statistics in medicine 20040630
Guillain-Barré syndrome seen in users of isotretinoin. BMJ (Clinical research ed.) 20040626
Hypersomnia associated with isotretinoin in a patient with recurrent major depressive disorder and acne vulgaris. Sleep 20040615
13-cis retinoic acid in head and neck cancer chemoprevention: results of a randomized trial from the Italian Head and Neck Chemoprevention Study Group. Oncology reports 20040601
American Academy of Dermatology Consensus Conference on the safe and optimal use of isotretinoin: summary and recommendations. Journal of the American Academy of Dermatology 20040601
Oral isotretinoin in the treatment of recalcitrant condylomata acuminata of the cervix: a randomised placebo controlled trial. Sexually transmitted infections 20040601
Isotretinoin-associated intracranial hypertension. Ophthalmology 20040601
A pilot study evaluating anxiety and depressive scores in acne patients treated with isotretinoin. The Journal of dermatological treatment 20040601
13-cis Retinoic acid (accutane) suppresses hippocampal cell survival in mice. Annals of the New York Academy of Sciences 20040601
Generic isotretinoin: a new risk for unborn children. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20040511
Isotretinoin and fenofibrate induce adiposity with distinct effect on metabolic profile in a rat model of the insulin resistance syndrome. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040501
The effect of isotretinoin on the pharmacokinetics and pharmacodynamics of ethinyl estradiol and norethindrone. Clinical pharmacology and therapeutics 20040501
Differentiating agents + low-dose chemotherapy in the management of old/poor prognosis patients with acute myeloid leukemia or myelodysplastic syndrome. Haematologica 20040501
Maintenance therapy with 13-cis retinoid acid in high-grade glioma at complete response after first-line multimodal therapy--a phase-II study. Journal of neuro-oncology 20040501
Interleukin-2- and interferon alfa-2a-based immunochemotherapy in advanced renal cell carcinoma: a Prospectively Randomized Trial of the German Cooperative Renal Carcinoma Chemoimmunotherapy Group (DGCIN). Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040401
Chemoprevention of squamous cell carcinoma in recessive dystrophic epidermolysis bullosa: results of a phase 1 trial of systemic isotretinoin. Journal of the American Academy of Dermatology 20040401
Keratoacanthoma centrifugum marginatum: a diagnostic and therapeutic challenge. Cutis 20040401
Retinoic acid in patients with radioiodine non-responsive thyroid carcinoma. Journal of endocrinological investigation 20040401
[Isotretinoin and increase in breast volume]. Annales de dermatologie et de venereologie 20040401
[Water alone is not enough. Proper cleansing is the basis of acne treatment]. MMW Fortschritte der Medizin 20040304
The renal retinoid system: time-dependent activation in experimental glomerulonephritis. American journal of physiology. Renal physiology 20040301
Isotretinoin in the treatment of granuloma annulare. The Annals of pharmacotherapy 20040301
Continuous 'microdose' isotretinoin in adult recalcitrant rosacea. Clinical and experimental dermatology 20040301
Safety and side effects of the acne drug, oral isotretinoin. Expert opinion on drug safety 20040301
A review of systemic retinoid therapy for acne and related conditions. Skin therapy letter 20040301
Novel regimen for the treatment of juvenile myelomonocytic leukemia (JMML). Leukemia research 20040201
Activity of interferon-alpha and isotretinoin in patients with advanced, refractory lymphoid malignancies. Cancer 20040201
Systemic therapy for acne vulgaris. Hospital medicine (London, England : 1998) 20040201
[Ultrastructural findings in the liver due to long-term retinol (isotretinoin) treatment. Significance of the perisinusoidal (Ito) cells]. Orvosi hetilap 20040125
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Reduced therapeutic activity of warfarin during treatment with oral isotretinoin. The British journal of dermatology 20040101
Isotretinoin treatment inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration. Novartis Foundation symposium 20040101
Treatment of an infantile acne with oral isotretinoin. European journal of dermatology : EJD 20040101
Ocular side effects associated with isotretinoin. Drugs of today (Barcelona, Spain : 1998) 20040101
Myths of isotretinoin therapy in patients with acne: a personal opinion. Journal of drugs in dermatology : JDD 20040101
The revolutionary field of chemoprevention. Journal of drugs in dermatology : JDD 20040101
Oral isotretinoin for severe acne in beta-thalassemia major. Dermatology (Basel, Switzerland) 20040101
13-cis Retinoic acid ameliorates benzoyl peroxide-induced oxidative stress and hyperproliferative response in murine skin: a chemopreventive study. Cancer detection and prevention 20040101
Subacromial/subdeltoid septic bursitis associated with isotretinoin therapy and corticosteroid injection. The Journal of the American Board of Family Practice 20040101
Disseminate and recurrent infundibulofolliculitis: response to isotretinoin. Journal of drugs in dermatology : JDD 20040101
[Isotretinoin and ulcerous colitis]. Anales del sistema sanitario de Navarra 20040101
Can transforming growth factor-beta1 and retinoids modify the activity of estradiol and antiestrogens in MCF-7 breast cancer cells? Acta biochimica Polonica 20040101
Polar hysteria: an expression of hypervitaminosis A. American journal of therapeutics 20040101
Oral isotretinoin in the treatment and prevention of cutaneous squamous cell carcinoma. Journal of drugs in dermatology : JDD 20040101
Can we ensure the safe use of known human teratogens? Introduction of generic isotretinoin in the US as an example. Drug safety 20040101
Acne: systemic treatment. Clinics in dermatology 20040101
[Chemoprevention possibilities of lung cancer]. Medicina (Kaunas, Lithuania) 20040101
Isotretinoin therapy: any need for laboratory assessment? West African journal of medicine 20040101
Body dysmorphic disorder of twins with facial illness after successful isotretinoin therapy. Acta dermato-venereologica 20040101
Low dose isotretinoin combined with tretinoin is effective to correct abnormalities of acne. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20040101
Accutane and pregnancy. Journal of the American Academy of Dermatology 20031201
Pregnancy rates associated with isotretinoin (Accutane) and the FDA. Journal of the American Academy of Dermatology 20031201
Retrospective survey of serum lipids in patients receiving more than three courses of isotretinoin. The Journal of dermatological treatment 20031201
Improvement of acanthosis nigricans on isotretinoin and metformin. Journal of drugs in dermatology : JDD 20031201
[Perifolliculitis capitis abscedens and suffodiens]. Annales de dermatologie et de venereologie 20031201
Night blindness, vitamin A deficiency, and isotretinoin psychotoxicity. Dermatology online journal 20031201
Wrinkles. Clinical evidence 20031201
Very low dose isotretinoin is effective in controlling seborrhea. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20031201
Low dose interleukin-2 and 13-cis-retinoic acid as maintenance therapy in patients with solid tumors responsive to chemotherapy. Journal of experimental & clinical cancer research : CR 20031201
[Psychiatric symptoms during isotretinoin therapy]. Nederlands tijdschrift voor geneeskunde 20031122
Prolonged thrombocytopenia associated with isotretinoin. The Annals of pharmacotherapy 20031101
[Acne vulgaris in connection with the use of progestagens in a hormonal IUD or a subcutaneous implant]. Nederlands tijdschrift voor geneeskunde 20031025
Response of recurrent anaplastic ependymoma to a combination of tamoxifen and isotretinoin. Neurology 20031014
Retinoid agonist isotretinoin ameliorates obstructive renal injury. The Journal of urology 20031001
Oral retinoid use reduces cutaneous squamous cell carcinoma risk in patients with psoriasis treated with psoralen-UVA: a nested cohort study. Journal of the American Academy of Dermatology 20031001
Are there racial and sex differences in the use of oral isotretinoin for acne management in the United States? Journal of the American Academy of Dermatology 20031001
The risk of second primary tumors after resection of stage I nonsmall cell lung cancer. The Annals of thoracic surgery 20031001
Acne, isotretinoin and depression. Drug and therapeutics bulletin 20031001
Generalized granuloma annulare. Dermatology online journal 20031001
Lipofuscin and macular degeneration. Nutrition reviews 20031001
A rare side-effect of systemic isotretinoin treatment: pyogenic granuloma. Journal of the European Academy of Dermatology and Venereology : JEADV 20030901
The inter-relationship between isotretinoin/acne and depression. Journal of the European Academy of Dermatology and Venereology : JEADV 20030901
Impetigo herpetiformis followed by generalized pustular psoriasis: more evidence of same disease entity. International journal of dermatology 20030901
Isotretinoin and antidepressant pharmacotherapy: a prescription sequence symmetry analysis. Journal of the American Academy of Dermatology 20030901
Gene and protein expression profiling during differentiation of neuroblastoma cells triggered by 13-cis retinoic acid. Journal of pediatric hematology/oncology 20030901
Treatment of 1-methyl-1-nitrosourea-induced mammary tumours with immunostimulatory CpG motifs and 13-cis retinoic acid in female rats: histopathological study. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030901
Pneumocystis carinii pneumonia: a late presentation following treatment for stage IV neuroblastoma. Pediatric hematology and oncology 20030901
Isotretinoin ameliorates renal damage in experimental acute renal allograft rejection. Transplantation 20030815
A phase I trial of weekly paclitaxel, 13- cis-retinoic acid, and interferon alpha in patients with prostate cancer and other advanced malignancies. Cancer chemotherapy and pharmacology 20030801
Systemic and topical drugs for aging skin. Journal of drugs in dermatology : JDD 20030801
Antibiotic resistance of Propionibacterium acnes in acne vulgaris. Dermatology nursing 20030801
Rapid deterioration in quality of life during interleukin-2- and alpha-interferon-based home therapy of renal cell carcinoma is associated with a good outcome. British journal of cancer 20030707
Acne: comparing hormonal approaches to antibiotics and isotretinoin. Expert opinion on pharmacotherapy 20030701
Analysis of long-term outcomes of combined modality therapy for cutaneous T-cell lymphoma. Journal of the American Academy of Dermatology 20030701
Favre-Racouchot-like disease after radiation therapy. Journal of the American Academy of Dermatology 20030701
Comparative bioequivalence study of two isotretinoin soft gel capsule formulations in healthy male volunteers. International journal of clinical pharmacology and therapeutics 20030701
[Enduring oral dryness after acne treatment]. Nederlands tijdschrift voor tandheelkunde 20030701
Long-term mini-doses of isotretinoin in the treatment of relapsing acne. The Journal of dermatology 20030701
Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: a North American Brain Tumor Consortium study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615
Herpetic whitlow during isotretinoin therapy. International journal of dermatology 20030601
Acute rhabdomyolysis and myoglobinuria associated with isotretinoin treatment. International journal of dermatology 20030601
Wrinkles. Clinical evidence 20030601
Impact of radiotherapy for high-risk neuroblastoma: a Children's Cancer Group study. International journal of radiation oncology, biology, physics 20030501
13-cis-retinoic acid for chemoprevention after colpoconization for cervical intraepithelial neoplasia. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20030501
Assessment of dermatopharmacokinetic approach in the bioequivalence determination of topical tretinoin gel products. Journal of the American Academy of Dermatology 20030501
Treatment of acne with isotretinoin: recommendations based on Australian experience. The Australasian journal of dermatology 20030501
Retinoids: fascinating up-and-coming scenario. The Journal of dermatology 20030501
The synthetic retinoid RO 13-6307 induces neuroblastoma differentiation in vitro and inhibits neuroblastoma tumour growth in vivo. International journal of cancer 20030420
Retinoic acid for redifferentiation of thyroid cancer--does it hold its promise? European journal of endocrinology 20030401
Eye problems with isotretinoin. Prescrire international 20030401
Generalized annular granuloma: response to isotretinoin. International journal of dermatology 20030401
Pharmacists' attitudes toward and practices with adolescents. Archives of pediatrics & adolescent medicine 20030401
The predictive value of cytologic testing in women with the human immunodeficiency virus who have low-grade squamous cervical lesions: a substudy of a randomized, phase III chemoprevention trial. American journal of obstetrics and gynecology 20030401
Effects of 13-cis-retinoic acid on chemoimmunotherapy of metastatic renal cell carcinoma--results of a retrospective analysis. Cancer biotherapy & radiopharmaceuticals 20030401
13-cis-retinoic acid competitively inhibits 3 alpha-hydroxysteroid oxidation by retinol dehydrogenase RoDH-4: a mechanism for its anti-androgenic effects in sebaceous glands? Biochemical and biophysical research communications 20030328
A highly efficient and sensitive screening method for trans-activation activity of estrogen receptors. Gene 20030313
[The Medical Products Agency is following up Roaccutane to assure patients' safety]. Lakartidningen 20030306
Decreasing serum concentrations of all-trans, 13-cis retinoic acids and retinol during fasting and caloric restriction. Journal of internal medicine 20030301
Taking advantage of a side effect of isotretinoin. Archives of dermatology 20030301
Two new adverse effects of isotretinoin. The British journal of dermatology 20030301
Conducting research using pharmacy databases. Managed care interface 20030301
Identification and management of oral isotretinoin use inconsistent with product labeling. Managed care interface 20030301
Second primary tumors in patients with upper aerodigestive tract cancers: joint effects of smoking and alcohol (United States). Cancer causes & control : CCC 20030301
[Doubtful re-evaluation of Roaccutane]. Lakartidningen 20030213
Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer. Journal of the National Cancer Institute 20030205
Sweet syndrome associated with 13-cis-retinoic acid (isotretinoin) therapy. Medical and pediatric oncology 20030201
The association between depression and isotretinoin use in acne. The Australian and New Zealand journal of psychiatry 20030201
Differentiation and apoptosis in human immortalized sebocytes. The Journal of investigative dermatology 20030201
Cloning of monkey RALDH1 and characterization of retinoid metabolism in monkey kidney proximal tubule cells. Journal of lipid research 20030201
Isotretinoin (Accutane) and serious psychiatric adverse events. Journal of the American Academy of Dermatology 20030201
[Classification of dermatologic manifestations in lupus erythematosus]. Annales de medecine interne 20030201
Accutane (isotretinoin) and psychiatric adverse effects. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030107
Management of acne. The Journal of family practice 20030101
Update and future of systemic acne treatment. Dermatology (Basel, Switzerland) 20030101
[Severe acne]. Annales de dermatologie et de venereologie 20030101
[Treatment of severe acne]. Annales de dermatologie et de venereologie 20030101
[An algorithm for the treatment of acne]. Annales de dermatologie et de venereologie 20030101
Overview of existing research and information linking isotretinoin (accutane), depression, psychosis, and suicide. American journal of therapeutics 20030101
A phase II study of 13-cis retinoic acid plus interferon alpha-2a in advanced stage penile carcinoma: an Eastern Cooperative Oncology Group study (E3893). Cancer investigation 20030101
Isotretinoin-induced bilateral sacroiliitis. Dermatology (Basel, Switzerland) 20030101
Treatment of gram-negative folliculitis in patients with acne. American journal of clinical dermatology 20030101
Perifolliculitis capitis abscedens et suffodiens successfully controlled with topical isotretinoin. European journal of dermatology : EJD 20030101
Guidelines for the management of acne vulgaris in adolescents. Paediatric drugs 20030101
[Value of isotretinoin in the treatment of acne in hemodialysis patients: apropos of 1 case]. Nephrologie 20030101
Acne in Apert's syndrome: treatment with isotretinoin. The Journal of dermatological treatment 20030101
Isotretinoin use and subsequent depression and suicide: presenting the evidence. American journal of clinical dermatology 20030101
Isotretinoin and psychiatric illness in adolescents and young adults. The Annals of pharmacotherapy 20030101
Retinoid-induced hypertriglyceridemia. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20030101
Isotretinoin treatment of acne in a patient with Apert syndrome. Pediatric dermatology 20030101
Does isotretinoin cause depression and suicide? Psychopharmacology bulletin 20030101
Oral isotretinoin and the use of 'conventional therapy'. Journal of managed care pharmacy : JMCP 20030101
Acne vulgaris. Skinmed 20030101
Phase I clinical trial of chemoimmunotherapy in combination with radiotherapy in stage IIIB cervical cancer patients. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20030101
Solid facial edema of acne: failure of treatment with isotretinoin. European journal of dermatology : EJD 20030101
Companies warned about unapproved Accutane. FDA consumer 20030101
Low-dose schema of isotretinoin in acne vulgaris. International journal of clinical pharmacology research 20030101
Progression of cervical disease among adolescents infected with HIV with low-grade squamous intraepithelial lesions. Journal of acquired immune deficiency syndromes (1999) 20021215
Familial Mediterranean fever: attacks during isotretinoin treatment. Journal of the American Academy of Dermatology 20021201
Extranodal Rosai-Dorfman disease with cutaneous, ophthalmic and laryngeal involvement: report of a case treated with isotretinoin. International journal of dermatology 20021201
[Axillary granular parakeratosis]. Biomedica : revista del Instituto Nacional de Salud 20021201
Wrinkles. Clinical evidence 20021201
Stiff-person syndrome associated with oral isotretinoin treatment. Neuromuscular disorders : NMD 20021101
Pregnancy and pregnancy rates in association with isotretinoin (Accutane). Journal of the American Academy of Dermatology 20021101
[ANCA-positive vasculitis of the skin and kidneys associated with acne conglobata]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20021101
Prospective study of depressive symptoms and quality of life in acne vulgaris patients treated with isotretinoin compared to antibiotic and topical therapy. The Australasian journal of dermatology 20021101
Is retinoid-induced osteopenia reversible? Archives of dermatology 20021101
Improvement of chronic generalized granuloma annulare with isotretinoin. Archives of dermatology 20021101
Phase I/II trial of accutane as a potentiator of carboplatin and paclitaxel in squamous cell carcinomas. American journal of clinical oncology 20021001
Is accutane really dangerous? The Medical letter on drugs and therapeutics 20020916
Multivariate survival analysis with doubly-censored data: application to the assessment of Accutane treatment for fibrodysplasia ossificans progressiva. Statistics in medicine 20020915
Pityriasis rubra pilaris in children. Journal of the American Academy of Dermatology 20020901
Topical adapalene gel 0.1% vs. isotretinoin gel 0.05% in the treatment of acne vulgaris: a randomized open-label clinical trial. The British journal of dermatology 20020901
Thirteen-year, long-term efficacy of interferon 2alpha and interleukin 2-based home therapy in patients with advanced renal cell carcinoma. Cancer 20020901
Clinical evaluation of Double Strength Isotrexin versus Benzamycin in the topical treatment of mild to moderate acne vulgaris. The Journal of dermatological treatment 20020901
Isotretinoin in Denmark -- 20 years on. The Journal of dermatological treatment 20020901
Prolonged remissions of cystic acne and conglobate acne with 13-cis-retinoic acid Peck GL, Olsen TG, Yoder FW et al. Clinical and experimental dermatology 20020901
Selected retinoids: determination by isocratic normal-phase HPLC. Endocrine regulations 20020901
Systematized epidermal nevus treated with isotretinoin. Journal of drugs in dermatology : JDD 20020901
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Superior effect of 9-cis retinoic acid (RA) compared with all-trans RA and 13-cis RA on the inhibition of clonogenic cell growth and the induction of apoptosis in OCI/AML-2 subclones: is the p53 pathway involved? British journal of haematology 20020801
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Phase 1B study of subcutaneously administered interleukin 2 in combination with 13-cis retinoic acid as maintenance therapy in advanced cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20010501
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