1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)hexahydro-1H-1,4-diazepin-1-yl]-
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The central mechanism underlying hypertension: a review of the roles of sodium ions, epithelial sodium channels, the renin-angiotensin-aldosterone system, oxidative stress and endogenous digitalis in the brain. | Hypertension research : official journal of the Japanese Society of Hypertension 20111101 |
Difficult-to-control hypertension due to bilateral aldosterone-producing adrenocortical microadenomas associated with a cortisol-producing adrenal macroadenoma. | Journal of human hypertension 20110201 |
Augmented antihypertensive effect of a fixed combination formula of candesartan and hydrochlorothiazide combined with furosemide in a patient on peritoneal dialysis. | Clinical and experimental nephrology 20110201 |
An immunohistochemical analysis of the neuroprotective effects of memantine, hyperbaric oxygen therapy, and brimonidine after acute ischemia reperfusion injury. | Molecular vision 20110101 |
Restraint stress induces connexin-43 translocation via α-adrenoceptors in rat heart. | Circulation journal : official journal of the Japanese Circulation Society 20101101 |
Ocular hypotensive effects of anti-glaucoma agents in mice. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20091001 |
New perspectives of infections in cardiovascular disease. | Current cardiology reviews 20090501 |
[The use of andante in the therapy of insomnia]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101 |
Review of nifedipine GITS in the treatment of high risk patients with coronary artery disease and hypertension. | Vascular health and risk management 20090101 |
Distinctive effects of carvedilol in the non-infarct zone: remodelling of the ligated rat heart linked to oxidative stress. | The Journal of international medical research 20090101 |
Possible mechanism of intraoperative floppy iris syndrome: a clinicopathological study. | The British journal of ophthalmology 20080801 |
Ocular pharmacokinetic/pharmacodynamic modeling for multiple anti-glaucoma drugs. | Biological & pharmaceutical bulletin 20080801 |
Comparison of the cardiac electrophysiological effects between doxazosin and bunazosin. | Journal of biomedical science 20080701 |
Comparison of the cardiac effects between quinazoline-based alpha1-adrenoceptor antagonists on occlusion-reperfusion injury. | Journal of biomedical science 20080301 |
Protective effects of carvedilol in murine model with the coxsackievirus B3-induced viral myocarditis. | Journal of cardiovascular pharmacology 20080101 |
Effects of adrenergic and cholinergic antagonists on diameter of nasolacrimal drainage system. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20071201 |
Role of alpha2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice. | British journal of pharmacology 20070901 |
The IOP-lowering effects and mechanism of action of tafluprost in prostanoid receptor-deficient mice. | The British journal of ophthalmology 20070501 |
[Case of pigmentary glaucoma treated with medical therapy, laser treatment, and trabeculotomy]. | Nippon Ganka Gakkai zasshi 20070201 |
Incidence of intraoperative floppy iris syndrome in patients on either systemic or topical alpha(1)-adrenoceptor antagonist. | American journal of ophthalmology 20070101 |
Beneficial effect of combination therapy with antihypertensive drugs in patients with hypertension. | Experimental and clinical cardiology 20070101 |
An alpha1-receptor blocker reduces plasma leptin levels in hypertensive patients with obesity and hyperleptinemia. | Hypertension research : official journal of the Japanese Society of Hypertension 20061001 |
Local regulation of skin blood flow during cooling involving presynaptic P2 purinoceptors in rats. | British journal of pharmacology 20060701 |
Correlation between the additive effect of bunazosin and the response to latanoprost on intraocular pressure in patients with glaucoma treated with bunazosin as adjunctive therapy to latanoprost. | Japanese journal of ophthalmology 20060101 |
Addition of or switch to topical bunazosin hydrochloride in elderly patients with normal-tension glaucoma: A one-year follow-up study. | Japanese journal of ophthalmology 20060101 |
The effects of prostaglandin analogues on IOP in prostanoid FP-receptor-deficient mice. | Investigative ophthalmology & visual science 20051101 |
Effects of different alpha-1 adrenoceptor blockers on proximal urethral function using in vivo isovolumetric pressure changes. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20051001 |
Alterations of alpha-adrenergic modulations of coronary microvascular tone in dogs with heart failure. | Journal of cardiac failure 20050601 |
Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits. | Clinical and experimental pharmacology & physiology 20050401 |
Amelioration of endothelin-1-induced optic nerve head ischemia by topical bunazosin. | Current eye research 20050201 |
alpha1-Adrenergic receptor antagonists induce production of IL-18 and expression of ICAM-1 and CD40 in human monocytes. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20050101 |
Evaluation of the additive effect of bunazosin on latanoprost in primary open-angle glaucoma. | Japanese journal of ophthalmology 20050101 |
Bunazosin, a selective alpha1-adrenoceptor antagonist, as an anti-glaucoma drug: effects on ocular circulation and retinal neuronal damage. | Cardiovascular drug reviews 20050101 |
Comparative study on the combined effects of bunazosin and nipradilol or timolol on intraocular pressure in normotensive rabbits. | Japanese journal of ophthalmology 20050101 |
Effects of topically instilled bunazosin, an alpha1-adrenoceptor antagonist, on constrictions induced by phenylephrine and ET-1 in rabbit retinal arteries. | Investigative ophthalmology & visual science 20041101 |
Effects of bunazosin hydrochloride on ciliary muscle constriction and matrix metalloproteinase activities. | Journal of glaucoma 20040801 |
Ocular pharmacokinetic/ pharmacodynamic modeling for bunazosin after instillation into rabbits. | Pharmaceutical research 20040501 |
Bunazosin hydrochloride reduces glutamate-induced neurotoxicity in rat primary retinal cultures. | Brain research 20040402 |
Efficacy of bunazosin hydrochloride 0.01% as adjunctive therapy of latanoprost or timolol. | Journal of glaucoma 20040201 |
Binding affinity of bunazosin, dorzolamide, and timolol to synthetic melanin. | Japanese journal of ophthalmology 20040101 |
Effects of topically instilled bunazosin hydrochloride and other ocular hypotensive drugs on endothelin-1-induced constriction in rabbit retinal arteries. | Japanese journal of ophthalmology 20040101 |
[Effects of ocular hypotensive agents on the circadian rhythm in intraocular pressure in rabbits as measured by telemetry]. | Nippon Ganka Gakkai zasshi 20030901 |
Amelioration by topical bunazosin hydrochloride of the impairment in ocular blood flow caused by nitric oxide synthase inhibition in rabbits. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030201 |
Additive effect of bunazosin on intraocular pressure when topically added to treatment with latanoprost in patients with glaucoma. | Japanese journal of ophthalmology 20030101 |
Effect of phenylephrine injected into the nucleus tractus solitarius of Sprague-Dawley rats and spontaneously hypertensive rats. | Brain research bulletin 20020815 |
Neuroprotective effects of nipradilol on purified cultured retinal ganglion cells. | Journal of glaucoma 20020601 |
The alpha(1D)-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction. | The Journal of clinical investigation 20020315 |
Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats. | Circulation 20020226 |
The renin-angiotensin and adrenergic nervous system in cardiac hypertrophy in fructose-fed rats. | American journal of hypertension 20020101 |
Purinergic modulation of vascular sympathetic neurotransmission. | Japanese journal of pharmacology 20020101 |
Noradrenaline stimulates 5-hydroxytryptamine release from mouse ileal tissues via alpha(2)-adrenoceptors. | European journal of pharmacology 20011207 |
Neuroprotective effect and intraocular penetration of nipradilol, a beta-blocker with nitric oxide donative action. | Investigative ophthalmology & visual science 20010301 |
Orthostatic hypotension: how to avoid it during antihypertensive therapy. | American journal of hypertension 19961101 |
[Comparison of selective alpha-1 blockades for alpha-receptors in human hypertrophied prostatic adenomas]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 19920301 |
Effects of regression of left ventricular hypertrophy following atenolol or bunazosin therapy on ischemic cardiac function and myocardial metabolism in spontaneously hypertensive rats. | Japanese circulation journal 19911201 |
Mechanism of myocardial injury in dogs with hypokalaemia. | Cardiovascular research 19880401 |