1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione
| Title | Journal |
|---|---|
| Effect of tetrahydrocurcumin on the profiles of drug-metabolizing enzymes induced by a high fat and high fructose diet in mice. | Chemico-biological interactions 20150905 |
| Tetrahydrocurcumin exerts protective effect on vincristine induced neuropathy: Behavioral, biochemical, neurophysiological and histological evidence. | Chemico-biological interactions 20150805 |
| Ameliorative efficacy of tetrahydrocurcumin against arsenic induced oxidative damage, dyslipidemia and hepatic mitochondrial toxicity in rats. | Chemico-biological interactions 20150625 |
| Tetrahydrocurcumin protects against cadmium-induced hypertension, raised arterial stiffness and vascular remodeling in mice. | PloS one 20140101 |
| Synthesis of quinoline derivatives of tetrahydrocurcumin and zingerone and evaluation of their antioxidant and antibacterial attributes. | Food chemistry 20130115 |
| Tissue distribution of (Lipocurc™) liposomal curcumin and tetrahydrocurcumin following two- and eight-hour infusions in Beagle dogs. | Anticancer research 20121001 |
| Infusion pharmacokinetics of Lipocurc™ (liposomal curcumin) and its metabolite tetrahydrocurcumin in Beagle dogs. | Anticancer research 20121001 |
| Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia. | Journal of molecular neuroscience : MN 20120501 |
| Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency. | Hypertension research : official journal of the Japanese Society of Hypertension 20120401 |
| Formation of tetrahydrocurcumin by reduction of curcumin with cultured plant cells of Marchantia polymorpha. | Natural product communications 20120401 |
| Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis. | Molecular nutrition & food research 20111201 |
| Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells. | Molecular nutrition & food research 20111101 |
| Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor. | Aging 20111101 |
| Bioactive antioxidant mixtures promote proliferation and migration on human oral fibroblasts. | Archives of oral biology 20110801 |
| Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with L-NAME-induced hypertension. | Naunyn-Schmiedeberg's archives of pharmacology 20110501 |
| Controlled release of oral tetrahydrocurcumin from a novel self-emulsifying floating drug delivery system (SEFDDS). | AAPS PharmSciTech 20110301 |
| In vitro inhibitory effect of tetrahydrocurcuminoids on Fusarium proliferatum growth and fumonisin B₁ biosynthesis. | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110201 |
| Tetrahydrocurcumin confers protection against amyloid β-induced toxicity. | Neuroreport 20110105 |
| Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents. | Chemico-biological interactions 20101205 |
| Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells. | Journal of periodontology 20101101 |
| Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity. | European journal of medicinal chemistry 20101001 |
| Tetrahydrocurcuminoid cream plus targeted narrowband UVB phototherapy for vitiligo: a preliminary randomized controlled study. | Photomedicine and laser surgery 20101001 |
| Comparative and combined effect of chlorogenic acid and tetrahydrocurcumin on antioxidant disparities in chemical induced experimental diabetes. | Molecular and cellular biochemistry 20100801 |
| Curcuminoids activate p38 MAP kinases and promote UVB-dependent signalling in keratinocytes. | Experimental dermatology 20100601 |
| Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species. | European journal of medicinal chemistry 20100301 |
| Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on streptozotocin-nicotinamide-induced diabetic rats. | General physiology and biophysics 20100301 |
| Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts. | Methods in molecular biology (Clifton, N.J.) 20100101 |
| Optimized turmeric extracts have potent anti-amyloidogenic effects. | Current Alzheimer research 20091201 |
| Curcumin is a potent DNA hypomethylation agent. | Bioorganic & medicinal chemistry letters 20090201 |
| Cardioprotective effect of tetrahydrocurcumin and rutin on lipid peroxides and antioxidants in experimentally induced myocardial infarction in rats. | Die Pharmazie 20090201 |
| Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300. | Biochemical and biophysical research communications 20081226 |
| Tetrahydrocurcumin inhibits HT1080 cell migration and invasion via downregulation of MMPs and uPA. | Acta pharmacologica Sinica 20080701 |
| Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice. | World journal of gastroenterology 20080407 |
| Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080401 |
| Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice. | Inflammopharmacology 20080401 |
| Effect of tetrahydrocurcumin on insulin receptor status in type 2 diabetic rats: studies on insulin binding to erythrocytes. | Journal of biosciences 20080301 |
| Comparative anti-inflammatory activities of curcumin and tetrahydrocurcumin based on the phenolic O-H bond dissociation enthalpy, ionization potential and quantum chemical descriptor. | Anticancer research 20080101 |
| Influence of tetrahydrocurcumin on tail tendon collagen contents and its properties in rats with streptozotocin-nicotinamide-induced type 2 diabetes. | Fundamental & clinical pharmacology 20071201 |
| The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice. | Biogerontology 20071001 |
| Influence of tetrahydrocurcumin on hepatic and renal functional markers and protein levels in experimental type 2 diabetic rats. | Basic & clinical pharmacology & toxicology 20071001 |
| Influence of tetrahydrocurcumin on erythrocyte membrane bound enzymes and antioxidant status in experimental type 2 diabetic rats. | Journal of ethnopharmacology 20070925 |
| Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. | Carcinogenesis 20070801 |
| Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells. | Experimental & molecular medicine 20070630 |
| The study of human skin irritation of a novel herbal skin care product and ingredients by human single closed patch testing. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070601 |
| Tetrahydrocurcumin prevents brain lipid peroxidation in streptozotocin-induced diabetic rats. | Journal of medicinal food 20070601 |
| Changes in glycoprotein components in streptozotocin--nicotinamide induced type 2 diabetes: influence of tetrahydrocurcumin from Curcuma longa. | Plant foods for human nutrition (Dordrecht, Netherlands) 20070301 |
| Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells. | Biochemical and biophysical research communications 20070223 |
| Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. | Molecular and cellular biochemistry 20070201 |
| Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives. | Biological & pharmaceutical bulletin 20070101 |
| Comparative cytotoxicity and ROS generation by curcumin and tetrahydrocurcumin following visible-light irradiation or treatment with horseradish peroxidase. | Anticancer research 20070101 |
| Antihyperlipidemic effect of curcumin and tetrahydrocurcumin in experimental type 2 diabetic rats. | Renal failure 20070101 |
| Comparative radical-scavenging activity of curcumin and tetrahydrocurcumin with thiols as measured by the induction period method. | In vivo (Athens, Greece) 20070101 |
| Tetrahydrocurcumin: effect on chloroquine-mediated oxidative damage in rat kidney. | Basic & clinical pharmacology & toxicology 20061101 |
| Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats. | Life sciences 20060927 |
| Effect of tetrahydrocurcumin on lipid peroxidation and lipids in streptozotocin-nicotinamide-induced diabetic rats. | Basic & clinical pharmacology & toxicology 20060801 |
| Validated LC/MS/MS assay for curcumin and tetrahydrocurcumin in rat plasma and application to pharmacokinetic study of phospholipid complex of curcumin. | Journal of pharmaceutical and biomedical analysis 20060224 |
| Effect of tetrahydrocurcumin on plasma antioxidants in streptozotocin-nicotinamide experimental diabetes. | Journal of basic and clinical physiology and pharmacology 20060101 |
| Tetrahydrocurcumin in plasma and urine: quantitation by high performance liquid chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925 |
| Relationship between intracellular ROS production and membrane mobility in curcumin- and tetrahydrocurcumin-treated human gingival fibroblasts and human submandibular gland carcinoma cells. | Oral diseases 20050701 |
| Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050430 |
| Effect of tetrahydrocurcumin on erythromycin estolate-induced lipid peroxidation in rats. | Journal of basic and clinical physiology and pharmacology 20050101 |
| Effect of tetrahydrocurcumin on blood glucose, plasma insulin and hepatic key enzymes in streptozotocin induced diabetic rats. | Journal of basic and clinical physiology and pharmacology 20050101 |
| Hydrogen-bonding and C-H...pi interactions in 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione (tetrahydrocurcumin). | Acta crystallographica. Section C, Crystal structure communications 20040801 |
| Interventions in aging and age-associated pathologies by means of nutritional approaches. | Annals of the New York Academy of Sciences 20040601 |
| Protective role of tetrahydrocurcumin against erythromycin estolate-induced hepatotoxicity. | Pharmacological research 20040501 |
| Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites. | Biochemical and biophysical research communications 20031010 |
| Contact allergy to tetrahydrocurcumin. | Contact dermatitis 20030401 |
| Studies on the role of some synthetic curcuminoid derivatives in the inhibition of tumour specific angiogenesis. | Journal of experimental & clinical cancer research : CR 20030301 |
| The protective effects of tetrahydrocurcumin on oxidative stress in cholesterol-fed rabbits. | Journal of atherosclerosis and thrombosis 20020101 |
| Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action. | Journal of medicinal chemistry 19970912 |