Home Other Building Blocks 4-Methylbenzylidene camphor

4-Methylbenzylidene camphor

CAS No.:
36861-47-9
Catalog Number:
AG003DRI
Molecular Formula:
C18H22O
Molecular Weight:
254.3667
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
98%(GC)
In Stock USA
United States
$150
- +
1g
98%(GC)
In Stock USA
United States
$429
- +
Product Description
Catalog Number:
AG003DRI
Chemical Name:
4-Methylbenzylidene camphor
CAS Number:
36861-47-9
Molecular Formula:
C18H22O
Molecular Weight:
254.3667
MDL Number:
MFCD00209662
IUPAC Name:
(3Z)-1,7,7-trimethyl-3-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-2-one
InChI:
InChI=1S/C18H22O/c1-12-5-7-13(8-6-12)11-14-15-9-10-18(4,16(14)19)17(15,2)3/h5-8,11,15H,9-10H2,1-4H3/b14-11-
InChI Key:
HEOCBCNFKCOKBX-KAMYIIQDSA-N
SMILES:
Cc1ccc(cc1)/C=C/1\C(=O)C2(C(C1CC2)(C)C)C
EC Number:
253-242-6
Properties
Complexity:
423  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
254.167g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
254.373g/mol
Monoisotopic Mass:
254.167g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
17.1A^2
Undefined Atom Stereocenter Count:
2  
Undefined Bond Stereocenter Count:
0
XLogP3:
4.5  
Literature
Title Journal
Comparison of Individual and Combined Effects of Four Endocrine Disruptors on Estrogen Receptor Beta Transcription in Cerebellar Cell Culture: The Modulatory Role of Estradiol and Triiodo-Thyronine. International journal of environmental research and public health 20160601
Simultaneous determination of ultraviolet filters in aqueous samples by plunger-in-needle solid-phase microextraction with graphene-based sol-gel coating as sorbent coupled with gas chromatography-mass spectrometry. Analytica chimica acta 20120912
Degradation of UV filters in sewage sludge and 4-MBC in liquid medium by the ligninolytic fungus Trametes versicolor. Journal of environmental management 20120815
Sunscreens: are they beneficial for health? An overview of endocrine disrupting properties of UV-filters. International journal of andrology 20120601
Ionic liquid based hollow fiber supported liquid phase microextraction of ultraviolet filters. Journal of chromatography. A 20120316
Impact of 4-methylbenzylidene camphor, daidzein, and estrogen on intact and osteotomized bone in osteopenic rats. The Journal of endocrinology 20111101
Acute and chronic toxicity of four frequently used UV filter substances for Desmodesmus subspicatus and Daphnia magna. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20110101
Vertical flow soil filter for the elimination of micro pollutants from storm and waste water. Chemosphere 20091101
Impact of 4-methylbenzylidene-camphor (4-MBC) during embryonic and fetal development in the neuroendocrine regulation of testicular axis in prepubertal and peripubertal male rats. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20091001
Determination of selected UV filters in indoor dust by matrix solid-phase dispersion and gas chromatography-tandem mass spectrometry. Journal of chromatography. A 20090731
Effect of daidzein, 4-methylbenzylidene camphor or estrogen on gastrocnemius muscle of osteoporotic rats undergoing tibia healing period. The Journal of endocrinology 20090501
Female sexual behavior, estrous cycle and gene expression in sexually dimorphic brain regions after pre- and postnatal exposure to endocrine active UV filters. Neurotoxicology 20090301
Co-loading of a photostabilizer with the sunscreen agent, butyl methoxydibenzoylmethane in solid lipid microparticles. Drug development and industrial pharmacy 20090201
Possible environmental effects of sunscreen run-off. Journal of the American Academy of Dermatology 20081101
Region-specific growth effects in the developing rat prostate following fetal exposure to estrogenic ultraviolet filters. Environmental health perspectives 20080701
Developmental toxicity of UV filters and environmental exposure: a review. International journal of andrology 20080401
Sunscreens in human plasma and urine after repeated whole-body topical application. Journal of the European Academy of Dermatology and Venereology : JEADV 20080401
Endocrine modulation and toxic effects of two commonly used UV screens on the aquatic invertebrates Potamopyrgus antipodarum and Lumbriculus variegatus. Environmental pollution (Barking, Essex : 1987) 20080301
Development of a method for the determination of UV filters in water samples using stir bar sorptive extraction and thermal desorption-gas chromatography-mass spectrometry. Journal of chromatography. A 20080201
Influence of solid lipid microparticle carriers on skin penetration of the sunscreen agent, 4-methylbenzylidene camphor. The Journal of pharmacy and pharmacology 20071201
Estrogen sensitivity of target genes and expression of nuclear receptor co-regulators in rat prostate after pre- and postnatal exposure to the ultraviolet filter 4-methylbenzylidene camphor. Environmental health perspectives 20071201
Occurrence and behavior of four of the most used sunscreen UV filters in a wastewater reclamation plant. Water research 20070801
Risk assessment of topically applied products. Toxicology 20070701
Complexation of the sunscreen agent, 4-methylbenzylidene camphor with cyclodextrins: effect on photostability and human stratum corneum penetration. Journal of pharmaceutical and biomedical analysis 20070509
Sunscreens and thyroid function in humans after short-term whole-body topical application: a single-blinded study. The British journal of dermatology 20070501
Sexually dimorphic gene regulation in brain as a target for endocrine disrupters: developmental exposure of rats to 4-methylbenzylidene camphor. Toxicology and applied pharmacology 20070115
A validated method for the determination of traces of UV filters in fish using LC-MS/MS. Analytical and bioanalytical chemistry 20061101
Toxicokinetics and biotransformation of 3-(4-methylbenzylidene)camphor in rats after oral administration. Toxicology and applied pharmacology 20061015
Kinetics of 3-(4-methylbenzylidene)camphor in rats and humans after dermal application. Toxicology and applied pharmacology 20061015
Comparison of effects of estradiol with those of octylmethoxycinnamate and 4-methylbenzylidene camphor on fat tissue, lipids and pituitary hormones. Toxicology and applied pharmacology 20060701
Occurrence of UV filters 4-methylbenzylidene camphor and octocrylene in fish from various Swiss rivers with inputs from wastewater treatment plants. Environmental science & technology 20060301
Comparison of effects of estradiol (E2) with those of octylmethoxycinnamate (OMC) and 4-methylbenzylidene camphor (4MBC)--2 filters of UV light - on several uterine, vaginal and bone parameters. Toxicology and applied pharmacology 20060201
Concentrations and specific loads of UV filters in sewage sludge originating from a monitoring network in Switzerland. Chemosphere 20060201
Evaluation of the photostability of different UV filter combinations in a sunscreen. International journal of pharmaceutics 20060113
Enantioselective separation of the sunscreen agent 3-(4-methylbenzylidene)-camphor by electrokinetic chromatography: Quantitative analysis in cosmetic formulations. Electrophoresis 20051001
Estrogen target gene regulation and coactivator expression in rat uterus after developmental exposure to the ultraviolet filter 4-methylbenzylidene camphor. Endocrinology 20050501
Shining a light on sunscreens. Endocrinology 20050501
Stereoisomer composition of the chiral UV filter 4-methylbenzylidene camphor in environmental samples. Environmental science & technology 20050501
Estrogen-like effects of ultraviolet screen 3-(4-methylbenzylidene)-camphor (Eusolex 6300) on cell proliferation and gene induction in mammalian and amphibian cells. Environmental research 20050301
Occurrence of some organic UV filters in wastewater, in surface waters, and in fish from Swiss Lakes. Environmental science & technology 20050215
Estrogenic activity and estrogen receptor beta binding of the UV filter 3-benzylidene camphor. Comparison with 4-methylbenzylidene camphor. Toxicology 20040701
Assessment of hormonal activity of UV filters in tadpoles of frog Xenopus laevis at environmental concentrations. Marine environmental research 20040101
Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes). Toxicology 20031215
Confirmation of uterotrophic activity of 3-(4-methylbenzylidine)camphor in the immature rat. Environmental health perspectives 20020501
Confirmation of uterotrophic activity for 4-MBC in the immature rat. Environmental health perspectives 20011101
Properties