NS-1643
| Title | Journal |
|---|---|
| Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643. | The Journal of pharmacology and experimental therapeutics 20120801 |
| Effects of the small molecule HERG activator NS1643 on Kv11.3 channels. | PloS one 20120101 |
| Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells. | Molecular pharmacology 20111101 |
| Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits. | Journal of cardiovascular pharmacology 20110201 |
| Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643. | Molecular pharmacology 20110101 |
| Enhanced repolarization capacity: new potential antiarrhythmic strategy based on HERG channel activation. | Current medicinal chemistry 20110101 |
| Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels. | British journal of pharmacology 20101001 |
| Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset. | The Journal of physiology 20090515 |
| Potent activation of large-conductance Ca2+-activated K+ channels by the diphenylurea 1,3-bis-[2-hydroxy-5-(trifluoromethyl)phenyl]urea (NS1643) in pituitary tumor (GH3) cells. | Molecular pharmacology 20081201 |
| Calcium-activated potassium channels contribute to human coronary microvascular dysfunction after cardioplegic arrest. | Circulation 20080930 |
| Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome. | Cardiovascular research 20080701 |
| Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243). | Molecular pharmacology 20080601 |
| Effects of potassium channel openers in the isolated perfused hypokalaemic murine heart. | Acta physiologica (Oxford, England) 20080501 |
| Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model. | Heart rhythm 20080501 |
| Erg K+ channels modulate contractile activity in the bovine epididymal duct. | American journal of physiology. Regulatory, integrative and comparative physiology 20080301 |
| Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells. | Molecular vision 20080101 |
| Activation of ERG2 potassium channels by the diphenylurea NS1643. | Neuropharmacology 20070801 |
| Mechanism of action of a novel human ether-a-go-go-related gene channel activator. | Molecular pharmacology 20060201 |
| Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643). | Molecular pharmacology 20060101 |
| Modulation of the Ca(2+)-dependent K+ channel, hslo, by the substituted diphenylurea NS 1608, paxilline and internal Ca2+. | Neuropharmacology 19960101 |