6-Azauracil
| Title | Journal |
|---|---|
| Molecular and functional properties of P2X receptors--recent progress and persisting challenges. | Purinergic signalling 20120901 |
| Electron configuration and hydrogen-bonding pattern in several thymine and uracil analogues studied by 1H-14N NQDR and DFT/QTAIM. | The journal of physical chemistry. B 20120802 |
| Role of Mediator in regulating Pol II elongation and nucleosome displacement in Saccharomyces cerevisiae. | Genetics 20120501 |
| Identification of Mutant Versions of the Spt16 Histone Chaperone That Are Defective for Transcription-Coupled Nucleosome Occupancy in Saccharomyces cerevisiae. | G3 (Bethesda, Md.) 20120501 |
| Inositol phosphate kinase Vip1p interacts with histone chaperone Asf1p in Saccharomyces cerevisiae. | Molecular biology reports 20120401 |
| Dissection of Pol II trigger loop function and Pol II activity-dependent control of start site selection in vivo. | PLoS genetics 20120401 |
| Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin. | Nature structural & molecular biology 20111001 |
| Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress. | The EMBO journal 20110817 |
| The new 5- or 6-azapyrimidine and cyanuric acid derivatives of l-ascorbic acid bearing the free C-5 hydroxy or C-4 amino group at the ethylenic spacer: CD-spectral absolute configuration determination and biological activity evaluations. | European journal of medicinal chemistry 20110701 |
| Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535. | Bioorganic & medicinal chemistry letters 20110615 |
| Synthesis and structure of ruthenium(IV) complexes featuring N-heterocyclic ligands with an N-H group as the hydrogen-bond donor: hydrogen interactions in solution and in the solid state. | Inorganic chemistry 20110606 |
| The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes. | Genes & development 20110601 |
| On the relaxation mechanisms of 6-azauracil. | The journal of physical chemistry. B 20110519 |
| N-aminoazetidinecarboxylic acid: direct access to a small-ring hydrazino acid. | The Journal of organic chemistry 20110121 |
| Guanine nucleotide pool imbalance impairs multiple steps of protein synthesis and disrupts GCN4 translational control in Saccharomyces cerevisiae. | Genetics 20110101 |
| Metabolic engineering and classic selection of the yeast Candida famata (Candida flareri) for construction of strains with enhanced riboflavin production. | Metabolic engineering 20110101 |
| Identification of lysine 37 of histone H2B as a novel site of methylation. | PloS one 20110101 |
| Elongator: an ancestral complex driving transcription and migration through protein acetylation. | Journal of biomedicine & biotechnology 20110101 |
| An investigation of a role for U2 snRNP spliceosomal components in regulating transcription. | PloS one 20110101 |
| Identification of the Arabidopsis REDUCED DORMANCY 2 gene uncovers a role for the polymerase associated factor 1 complex in seed dormancy. | PloS one 20110101 |
| p53 Interacts with RNA polymerase II through its core domain and impairs Pol II processivity in vivo. | PloS one 20110101 |
| The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses. | PloS one 20110101 |
| Overruling the energy gap law: fast triplet formation in 6-azauracil. | Physical chemistry chemical physics : PCCP 20101228 |
| Overexpression of SNG1 causes 6-azauracil resistance in Saccharomyces cerevisiae. | Current genetics 20100601 |
| Roles for H2A.Z and its acetylation in GAL1 transcription and gene induction, but not GAL1-transcriptional memory. | PLoS biology 20100601 |
| Triplet formation of 6-azauridine and singlet oxygen sensitization with UV light irradiation. | Physical chemistry chemical physics : PCCP 20100521 |
| Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability. | Molecular cell 20100423 |
| A nucleosome surface formed by histone H4, H2A, and H3 residues is needed for proper histone H3 Lys36 methylation, histone acetylation, and repression of cryptic transcription. | The Journal of biological chemistry 20100409 |
| Improving binding specificity of pharmacological chaperones that target mutant superoxide dismutase-1 linked to familial amyotrophic lateral sclerosis using computational methods. | Journal of medicinal chemistry 20100408 |
| The YEATS domain of Taf14 in Saccharomyces cerevisiae has a negative impact on cell growth. | Molecular genetics and genomics : MGG 20100401 |
| The Snf2 homolog Fun30 acts as a homodimeric ATP-dependent chromatin-remodeling enzyme. | The Journal of biological chemistry 20100326 |
| Functional characterization and virulence study of ADE8 and GUA1 genes involved in the de novo purine biosynthesis in Candida albicans. | FEMS yeast research 20100301 |
| A Bre1-associated protein, large 1 (Lge1), promotes H2B ubiquitylation during the early stages of transcription elongation. | The Journal of biological chemistry 20100122 |
| A chemical genetic screen for modulators of asymmetrical 2,2'-dimeric naphthoquinones cytotoxicity in yeast. | PloS one 20100101 |
| Histone H3 serine 57 and lysine 56 interplay in transcription elongation and recovery from S-phase stress. | PloS one 20100101 |
| The SWR1 histone replacement complex causes genetic instability and genome-wide transcription misregulation in the absence of H2A.Z. | PloS one 20100101 |
| Intersystem crossing to excited triplet state of aza analogues of nucleic acid bases in acetonitrile. | The journal of physical chemistry. A 20091105 |
| Global analysis of mutual interaction surfaces of nucleosomes with comprehensive point mutants. | Genes to cells : devoted to molecular & cellular mechanisms 20091101 |
| Yeast genetic analysis reveals the involvement of chromatin reassembly factors in repressing HIV-1 basal transcription. | PLoS genetics 20090101 |
| The SNF2-family member Fun30 promotes gene silencing in heterochromatic loci. | PloS one 20090101 |
| Excited state characteristics of 6-azauracil in acetonitrile: drastically different relaxation mechanism from uracil. | The journal of physical chemistry. A 20081225 |
| H3K9 methylation regulates growth and development in Aspergillus fumigatus. | Eukaryotic cell 20081201 |
| Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway. | PLoS genetics 20081201 |
| Histone H3 K36 methylation is mediated by a trans-histone methylation pathway involving an interaction between Set2 and histone H4. | Genes & development 20081015 |
| Neo-clinicians, clinical trials, and the reorganization of medical research in Paris hospitals after the Second World War: the trajectory of Jean Bernard. | Medical history 20081001 |
| Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways. | The EMBO journal 20080917 |
| Identification and characterization of two trypanosome TFIIS proteins exhibiting particular domain architectures and differential nuclear localizations. | Molecular microbiology 20080901 |
| Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid state. | Journal of the American Chemical Society 20080716 |
| Genomewide recruitment analysis of Rpb4, a subunit of polymerase II in Saccharomyces cerevisiae, reveals its involvement in transcription elongation. | Eukaryotic cell 20080601 |
| Reversal of RNA polymerase II ubiquitylation by the ubiquitin protease Ubp3. | Molecular cell 20080523 |
| The tumor suppressor p53 associates with gene coding regions and co-traverses with elongating RNA polymerase II in an in vivo model. | Oncogene 20080424 |
| Cell-to-cell stochastic variation in gene expression is a complex genetic trait. | PLoS genetics 20080401 |
| 6-Azauracil or 8-aza-7-deazaadenine nucleosides and oligonucleotides: the effect of 2'-fluoro substituents and nucleobase nitrogens on conformation and base pairing. | Organic & biomolecular chemistry 20080207 |
| Chemogenetic fingerprinting by analysis of cellular growth dynamics. | BMC chemical biology 20080101 |
| Recruitment of P-TEFb (Cdk9-Pch1) to chromatin by the cap-methyl transferase Pcm1 in fission yeast. | The EMBO journal 20070321 |
| Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL. | The Journal of biological chemistry 20070223 |
| Global analysis of functional surfaces of core histones with comprehensive point mutants. | Genes to cells : devoted to molecular & cellular mechanisms 20070101 |
| [Lectins from Sambucus nigra L inflorescences: isolation and investigation of biological activity using procaryotic test-systems]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101 |
| 6-azauracil sensitivity assay for yeast. | CSH protocols 20061201 |
| Combined use of two transcriptional reporters improves signalling assays for G protein-coupled receptors in fission yeast. | Yeast (Chichester, England) 20060901 |
| Mutations in the Saccharomyces cerevisiae RPB1 gene conferring hypersensitivity to 6-azauracil. | Genetics 20060401 |
| [The synthesis of arginine derivatives of chromone and azauracil]. | Bioorganicheskaia khimiia 20060101 |
| Folding free energies of 5'-UTRs impact post-transcriptional regulation on a genomic scale in yeast. | PLoS computational biology 20051201 |
| Altered nucleosome occupancy and histone H3K4 methylation in response to 'transcriptional stress'. | The EMBO journal 20050706 |
| A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. | Molecular and cellular biology 20050401 |
| Distinction and relationship between elongation rate and processivity of RNA polymerase II in vivo. | Molecular cell 20050318 |
| Synthesis and biological activity of some unsaturated 6-azauracil acyclonucleosides. | Nucleosides, nucleotides & nucleic acids 20050101 |
| Large-scale screening of yeast mutants for sensitivity to the IMP dehydrogenase inhibitor 6-azauracil. | Yeast (Chichester, England) 20040201 |
| The uses of genome-wide yeast mutant collections. | Genome biology 20040101 |
| Functional distinctions between IMP dehydrogenase genes in providing mycophenolate resistance and guanine prototrophy to yeast. | The Journal of biological chemistry 20030801 |
| Triazines facilitate neurotransmitter release of synaptic terminals located in hearts of frog (Rana ridibunda) and honeybee (Apis mellifera) and in the ventral nerve cord of a beetle (Tenebrio molitor). | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030701 |
| Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast. | Science (New York, N.Y.) 20030418 |
| The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. | The Journal of biological chemistry 20030314 |
| Cleavage, but not read-through, stimulation activity is responsible for three biologic functions of transcription elongation factor S-II. | The Journal of biological chemistry 20030307 |
| Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics. | Bioorganic & medicinal chemistry letters 20030210 |
| Use of RNA yeast polymerase II mutants in studying transcription elongation. | Methods in enzymology 20030101 |
| Association of the histone methyltransferase Set2 with RNA polymerase II plays a role in transcription elongation. | The Journal of biological chemistry 20021220 |
| A role for SSU72 in balancing RNA polymerase II transcription elongation and termination. | Molecular cell 20021101 |
| Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism. | Molecular genetics and genomics : MGG 20021001 |
| SDT1/SSM1, a multicopy suppressor of S-II null mutant, encodes a novel pyrimidine 5'-nucleotidase. | The Journal of biological chemistry 20020614 |
| The Paf1 complex physically and functionally associates with transcription elongation factors in vivo. | The EMBO journal 20020402 |
| Genetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation. | Genetics 20010601 |
| Analysis of gene induction and arrest site transcription in yeast with mutations in the transcription elongation machinery. | The Journal of biological chemistry 20010413 |
| Involvement of yeast carboxy-terminal domain kinase I (CTDK-I) in transcription elongation in vivo. | Gene 20010404 |
| Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro. | Annals of tropical medicine and parasitology 19961201 |
| Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii. | Biochemical pharmacology 19940817 |
| 2,4-Bis(arylamino)-5-methylpyrimidines as antimicrobial agents. | Journal of medicinal chemistry 19670901 |
| 2,4-Bis(arylamino)pyrimidines as antimicrobial agents. | Journal of medicinal chemistry 19660501 |