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Home Other Building Blocks 1,2,3,4,5,6-HEXABROMOCYCLOHEXANE

1,2,3,4,5,6-HEXABROMOCYCLOHEXANE

CAS No.:
1837-91-8
Catalog Number:
AG003D9L
Molecular Formula:
C6H6Br6
Molecular Weight:
557.5358
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Product Description
Catalog Number:
AG003D9L
Chemical Name:
1,2,3,4,5,6-HEXABROMOCYCLOHEXANE
CAS Number:
1837-91-8
Molecular Formula:
C6H6Br6
Molecular Weight:
557.5358
MDL Number:
MFCD00059127
IUPAC Name:
1,2,3,4,5,6-hexabromocyclohexane
InChI:
InChI=1S/C6H6Br6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H
InChI Key:
QFQZKISCBJKVHI-UHFFFAOYSA-N
SMILES:
BrC1C(Br)C(Br)C(C(C1Br)Br)Br
NSC Number:
7908
Properties
Complexity:
104  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
557.551g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
557.538g/mol
Monoisotopic Mass:
551.557g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5  
Literature
Title Journal
Growth hormone-stimulated insulin-like growth factor-1 expression in rainbow trout (Oncorhynchus mykiss) hepatocytes is mediated by ERK, PI3K-AKT, and JAK-STAT. American journal of physiology. Regulatory, integrative and comparative physiology 20110701
ERK, Akt, and STAT5 are Differentially Activated by the Two Growth Hormone Receptor Subtypes of a Teleost Fish (Oncorhynchus Mykiss). Frontiers in endocrinology 20110101
Prolactin-induced Jak2 phosphorylation of RUSH: a key element in Jak/RUSH signaling. Molecular and cellular endocrinology 20100830
Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients. Oncogene 20090409
Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth. The Journal of biological chemistry 20070209
Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophosphorylation [correction of autophophorylation]. Journal of medicinal chemistry 20050407
Properties