1-(2-Trifluoromethylphenyl)imidazole
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Stress response to cadmium and manganese in Paracentrotus lividus developing embryos is mediated by nitric oxide. | Aquatic toxicology (Amsterdam, Netherlands) 20141101 |
cGMP Signaling, Phosphodiesterases and Major Depressive Disorder. | Current neuropharmacology 20111201 |
Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain. | Journal of medicinal chemistry 20111027 |
Effects of nitric oxide synthase inhibitors 1-(2-trifluoromethylphenyl)--imidazole (TRIM) and 7-nitroindazole (7-NI) on learning and memory in mice. | Fundamental & clinical pharmacology 20110601 |
Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review. | Journal of pharmacy & bioallied sciences 20110101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Nitric oxide is involved in the regulation of marble-burying behavior. | Neuroscience letters 20100809 |
Effects of inhibition of neuronal nitric oxide synthase on basal retinal blood flow regulation. | Experimental eye research 20091101 |
Evidence of a Ca(2+)-(*)NO-cGMP signaling pathway controlling zoospore biogenesis in the aquatic fungus Blastocladiella emersonii. | Fungal genetics and biology : FG & B 20090801 |
Involvement of capsaicin-sensitive afferent nerves in the proteinase-activated receptor 2-mediated vasodilatation in the rat dura mater. | Neuroscience 20090707 |
Role of extracellular Na+, Ca2+-activated Cl- channels and BK channels in the contraction of Ca2+ store-depleted tracheal smooth muscle. | Clinical and experimental pharmacology & physiology 20090701 |
Direct evidence of nitric oxide release from neuronal nitric oxide synthase activation in the left ventricle as a result of cervical vagus nerve stimulation. | The Journal of physiology 20090615 |
Paradoxical facilitation of pentylenetetrazole-induced convulsion susceptibility in mice lacking neuronal nitric oxide synthase. | Neuroscience 20090317 |
Effects of neuronal and inducible NOS inhibitor 1-[2-(trifluoromethyl) phenyl] imidazole (TRIM) in unpredictable chronic mild stress procedure in mice. | Pharmacology, biochemistry, and behavior 20090301 |
Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice. | Molecular brain 20090101 |
Nitric oxide modulates the cardiovascular effects elicited by acetylcholine in the NTS of awake rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20081201 |
Neuronal nitric oxide synthase-derived hydrogen peroxide is a major endothelium-dependent relaxing factor. | American journal of physiology. Heart and circulatory physiology 20081201 |
Neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole augment the effects of antidepressants acting via serotonergic system in the forced swimming test in rats. | Pharmacology, biochemistry, and behavior 20081001 |
Activities of 7-nitroindazole and 1-(2-(trifluoromethylphenyl)-imidazole independent of neuronal nitric-oxide synthase inhibition. | The Journal of pharmacology and experimental therapeutics 20080501 |
A physiological role for nitric oxide in the centrally mediated sympathetic and somatomotor ejaculatory response in anesthetized male Wistar rats. | Neuroscience 20071205 |
Pharmacological characterization and molecular determinants of the activation of transient receptor potential V2 channel orthologs by 2-aminoethoxydiphenyl borate. | Molecular pharmacology 20071101 |
Nitric oxide increases GLUT4 expression and regulates AMPK signaling in skeletal muscle. | American journal of physiology. Endocrinology and metabolism 20071001 |
Nitric oxide synthase isoform inhibition before whole body ischemia reperfusion in pigs: vital or protective? | Resuscitation 20070901 |
Neuronal nitric oxide synthase (nNOS) blockade within the ventrolateral medulla differentially modulates cardiovascular responses and nNOS expression during static skeletal muscle contraction. | Brain research 20070530 |
Modulation of cardiovascular responses and neurotransmission during peripheral nociception following nNOS antagonism within the periaqueductal gray. | Brain research 20070427 |
Different roles of nitric oxide synthase isoforms in cardiopulmonary resuscitation in pigs. | Resuscitation 20070401 |
Effects of TRIM on tension, intracellular calcium and nitrergic transmission in the rat anococcygeus muscle. | Nitric oxide : biology and chemistry 20070201 |
Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice. | Molecular pain 20070101 |
Involvement of endogenous nitric oxide in the regulation of K+ channel activity in cultured human proximal tubule cells. | The journal of physiological sciences : JPS 20061201 |
A store-operated current (SOC) mediates oxytocin autocontrol in the developing rat hypothalamus. | The European journal of neuroscience 20060701 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Role of nitric oxide on ATP-induced Ca2+ signaling in outer hair cells of the guinea pig cochlea. | Brain research 20060407 |
Role of nitric oxide and prostanoids in attenuation of rapid baroreceptor resetting. | American journal of physiology. Heart and circulatory physiology 20060301 |
In vivo inhibition of nitric oxide synthase impairs upregulation of contractile protein mRNA in overloaded plantaris muscle. | Journal of applied physiology (Bethesda, Md. : 1985) 20060101 |
Nitric oxide and thromboxane A2 modulate pulmonary pressure after ischemia and intestinal reperfusion. | Transplantation proceedings 20060101 |
[Effects of new nitric oxide synthase inhibitors on spontaneous locomotor activity]. | Medicinski pregled 20060101 |
Co-expression and modulation of neuronal and endothelial nitric oxide synthase in human endothelial cells. | Journal of molecular and cellular cardiology 20041101 |
The role of neuronal nitric oxide in the vagal control of cardiac interval of the rat heart in vitro. | Autonomic neuroscience : basic & clinical 20040430 |
Impaired nitric oxide production of the myenteric plexus in colitis detected by a new bioimaging system. | The Journal of surgical research 20040401 |
Influence of endogenous nitric oxide on sympathetic vasoconstriction in normoxia, acute and chronic systemic hypoxia in the rat. | The Journal of physiology 20040316 |
Positive N-methyl-D-aspartate receptor modulation by selective glycine transporter-1 inhibition in the rat dorsal spinal cord in vivo. | Neuroscience 20040101 |
The neuronal nitric oxide synthase inhibitor, TRIM, as a neuroprotective agent: effects in models of cerebral ischaemia using histological and magnetic resonance imaging techniques. | Brain research 20031212 |
Cardiovascular responses and neurotransmitter changes following blockade of nNOS within the ventrolateral medulla during static muscle contraction. | Brain research 20030704 |
Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice. | Behavioural brain research 20030318 |
Inhibitory effects of NO on carotid body: contribution of neural and endothelial nitric oxide synthase isoforms. | American journal of physiology. Lung cellular and molecular physiology 20030101 |
Study on the influence of potent inhibitors of neuronal nitric oxide synthase on the antinociceptive and anticonvulsant activity of benzodiazepines in mice. | Polish journal of pharmacology 20030101 |
Contribution of neural and endothelial isoforms of the nitric oxide synthase to the inhibitory effects of NO on the cat carotid body. | Advances in experimental medicine and biology 20030101 |
Different strains of rats show different sensitivity to block of long-term potentiation by nitric oxide synthase inhibitors. | European journal of pharmacology 20021220 |
Role of spinal nitric oxide in the inhibitory effect of [D-Pen2, D-Pen5]-enkephalin on ascending dorsal horn neurons in normal and diabetic rats. | The Journal of pharmacology and experimental therapeutics 20021201 |
Nitric oxide inhibits spinally projecting paraventricular neurons through potentiation of presynaptic GABA release. | Journal of neurophysiology 20021101 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Reflex choroidal blood flow responses of the eyeball following somatic sensory stimulation in rats. | Autonomic neuroscience : basic & clinical 20020418 |
Neuronal NO mediates cerebral vasodilator responses to K+ in hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20020401 |
Augmented expression of neuronal nitric oxide synthase in the atria parasympathetically decreases heart rate during acute myocardial infarction in rats. | Circulation 20020129 |
Contribution of cerebral nitric oxide to bladder overactivity after cerebral infarction in rats. | The Journal of urology 20020101 |
Nitric oxide facilitates vagal control of heart rate via actions in the cardiac parasympathetic ganglia of the anaesthetised dog. | Experimental physiology 20020101 |
Peripheral vagal control of heart rate is impaired in neuronal NOS knockout mice. | American journal of physiology. Heart and circulatory physiology 20011201 |
Role of nitric oxide on in vitro human eosinophil migration. | Biochemical pharmacology 20011115 |
Major role for neuronal NO synthase in curtailing choroidal blood flow autoregulation in newborn pig. | Journal of applied physiology (Bethesda, Md. : 1985) 20011001 |
Selective inhibition of thapsigargin-induced contraction and capacitative calcium entry in mouse anococcygeus by trifluoromethylphenylimidazole (TRIM). | British journal of pharmacology 20010901 |
Inhibition of neuronal nitric oxide reduces heart rate variability in the anaesthetised dog. | Experimental physiology 20010901 |
Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles. | Bioorganic & medicinal chemistry letters 20010507 |
Inhibition of neuronal nitric oxide synthase results in neurodegenerative changes in the axotomised dorsal root ganglion neurons: evidence for a neuroprotective role of nitric oxide in vivo. | Neuroscience research 20010501 |
Cerebral hyperemia and nitric oxide synthase in rats with ammonia-induced brain edema. | Journal of hepatology 20010401 |
Anticonvulsant activity of new and potent inhibitors of nitric oxide synthase. | Brain research bulletin 19970101 |