Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis.

Archives of toxicology 20130701

2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells.

Chemico-biological interactions 20130525

Xanthohumol induces phase II enzymes via Nrf2 in human hepatocytes in vitro.

Toxicology in vitro : an international journal published in association with BIBRA 20130201

Xanthohumol induces different cytotoxicity and apoptotic pathways in malignant and normal astrocytes.

Phytotherapy research : PTR 20121101

Prenylated chalcone xanthohumol associates with histones in breast cancer cells--a novel target identified by a monoclonal antibody.

Molecular nutrition & food research 20121101

Xanthohumol prevents carbon tetrachloride-induced acute liver injury in rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001

The AKT/NF-κB inhibitor xanthohumol is a potent anti-lymphocytic leukemia drug overcoming chemoresistance and cell infiltration.

Biochemical pharmacology 20120615

Xanthohumol inhibits growth and vascularization of developing endometriotic lesions.

Human reproduction (Oxford, England) 20120601

Inverse Virtual Screening allows the discovery of the biological activity of natural compounds.

Bioorganic & medicinal chemistry 20120601

Xanthohumol impairs autophagosome maturation through direct inhibition of valosin-containing protein.

ACS chemical biology 20120518

Protective effects of arachidonic acid against palmitic acid-mediated lipotoxicity in HIT-T15 cells.

Molecular and cellular biochemistry 20120501

Protective effects of xanthohumol against the genotoxicity of heterocyclic aromatic amines MeIQx and PhIP in bacteria and in human hepatoma (HepG2) cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301

Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.

Molecular nutrition & food research 20120301

Neuroprotective effects of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus), in ischemic stroke of rats.

Journal of agricultural and food chemistry 20120227

Xanthohumol, a prenylated chalcone derived from hops, suppresses cancer cell invasion through inhibiting the expression of CXCR4 chemokine receptor.

Current molecular medicine 20120201

Preliminary in vitro study on the effect of xanthohumol on rumen methanogenesis.

Archives of animal nutrition 20120201

Xanthohumol-supplemented beer modulates angiogenesis and inflammation in a skin wound healing model. Involvement of local adipocytes.

Journal of cellular biochemistry 20120101

Flavonoid production in transgenic hop (Humulus lupulus L.) altered by PAP1/MYB75 from Arabidopsis thaliana L.

Plant cell reports 20120101

Search method for inhibitors of Staphyloxanthin production by methicillin-resistant Staphylococcus aureus.

Biological & pharmaceutical bulletin 20120101

Geranyl derivative of phloroacetophenone induces cancer cell-specific apoptosis through Bax-mediated mitochondrial pathway in MCF-7 human breast cancer cells.

Biological & pharmaceutical bulletin 20120101

Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis.

International journal of clinical and experimental pathology 20120101

Pitfalls in cell culture work with xanthohumol.

Die Pharmazie 20120101

Anticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation.

Journal of experimental therapeutics & oncology 20120101

Xanthohumol uptake and intracellular kinetics in hepatocytes, hepatic stellate cells, and intestinal cells.

Journal of agricultural and food chemistry 20111228

Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways.

Journal of natural products 20111227

Xanthohumol decreases Notch1 expression and cell growth by cell cycle arrest and induction of apoptosis in epithelial ovarian cancer cell lines.

Gynecologic oncology 20110801

Novel application of square-wave adsorptive-stripping voltammetry for the determination of xanthohumol in spent hops.

Journal of agricultural and food chemistry 20110727

Magnetic mixed hemimicelles solid-phase extraction of xanthohumol in beer coupled with high-performance liquid chromatography determination.

Journal of separation science 20110601

Xanthohumol from the hop plant stimulates osteoblast differentiation by RUNX2 activation.

Biochemical and biophysical research communications 20110527

Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor.

Journal of medicinal chemistry 20110310

Inhibitors of hyaluronan export from hops prevent osteoarthritic reactions.

Molecular nutrition & food research 20110301

Anti-inflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells.

Neurochemistry international 20110201

Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS.

Analytical chemistry 20110201

Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines.

Nutrition research (New York, N.Y.) 20110201

In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds.

Nutrition and cancer 20110101

Surface plasmon resonance analysis of interactions between diacylglycerol acyltransferase and its interacting molecules.

Bioscience, biotechnology, and biochemistry 20110101

Polyphenols in alcoholic beverages activating constitutive androstane receptor CAR.

Bioscience, biotechnology, and biochemistry 20110101

Quantification of xanthohumol, isoxanthohumol, 8-prenylnaringenin, and 6-prenylnaringenin in hop extracts and derived capsules using secondary standards.

Talanta 20101215

Re-evaluation of superoxide scavenging capacity of xanthohumol.

Free radical research 20101201

Xanthohumol and related prenylated flavonoids inhibit inflammatory cytokine production in LPS-activated THP-1 monocytes: structure-activity relationships and in silico binding to myeloid differentiation protein-2 (MD-2).

Planta medica 20101001

Recovery and metabolism of xanthohumol in germ-free and human microbiota-associated rats.

Molecular nutrition & food research 20101001

Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).

Mutation research 20100910

Growth inhibitory and apoptosis-inducing effects of xanthohumol, a prenylated chalone present in hops, in human prostate cancer cells.

Anticancer research 20100901

Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100801

Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis.

Molecular nutrition & food research 20100701

Triggering of dendritic cell apoptosis by xanthohumol.

Molecular nutrition & food research 20100701

Xanthohumol feeding does not impair organ function and homoeostasis in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100701

Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism.

Molecular nutrition & food research 20100701

Disposition of hop prenylflavonoids in human breast tissue.

Molecular nutrition & food research 20100701

Identification of new phase II metabolites of xanthohumol in rat in vivo biotransformation of hop extracts using high-performance liquid chromatography electrospray ionization tandem mass spectrometry.

Journal of chromatography. A 20100618

Synthesis, cytotoxicity, anti-oxidative and anti-inflammatory activity of chalcones and influence of A-ring modifications on the pharmacological effect.

European journal of medicinal chemistry 20100601

Isolation of phenolic compounds from hop extracts using polyvinylpolypyrrolidone: characterization by high-performance liquid chromatography-diode array detection-electrospray tandem mass spectrometry.

Journal of chromatography. A 20100507

Xanthohumol inhibits IL-12 production and reduces chronic allergic contact dermatitis.

International immunopharmacology 20100501

Determination of xanthohumol in beer based on cloud point extraction coupled with high performance liquid chromatography.

Talanta 20100415

Xanthohumol enhances antiviral effect of interferon alpha-2b against bovine viral diarrhea virus, a surrogate of hepatitis C virus.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20100401

Xanthohumol inhibits the neuroendocrine transcription factor achaete-scute complex-like 1, suppresses proliferation, and induces phosphorylated ERK1/2 in medullary thyroid cancer.

American journal of surgery 20100301

Xanthohumol, a prenylated chalcone derived from hops, inhibits proliferation, migration and interleukin-8 expression of hepatocellular carcinoma cells.

International journal of oncology 20100201

Direct inhibition of elastase and matrixmetalloproteinases and stimulation of biosynthesis of fibrillar collagens, elastin, and fibrillins by xanthohumol.

Journal of cosmetic science 20100101

Modulation of aflatoxin B1-mediated genotoxicity in primary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthohumols.

Toxicological sciences : an official journal of the Society of Toxicology 20091201

Inhibition of bovine viral diarrhea virus in vitro by xanthohumol: comparisons with ribavirin and interferon-alpha and implications for the development of anti-hepatitis C virus agents.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091105

Characterization of prenylflavonoids and hop bitter acids in various classes of Czech beers and hop extracts using high-performance liquid chromatography-mass spectrometry.

Journal of chromatography. A 20091023

Antioxidant effects of xanthohumol and functional impact on hepatic ischemia-reperfusion injury.

Journal of natural products 20091001

Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia.

Anticancer research 20091001

Xanthohumol from hop (Humulus lupulus L.) is an efficient inhibitor of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha release in LPS-stimulated RAW 264.7 mouse macrophages and U937 human monocytes.

Journal of agricultural and food chemistry 20090826

Inhibition of suicidal erythrocyte death by xanthohumol.

Journal of agricultural and food chemistry 20090826

Anti-obesity effects of xanthohumol plus guggulsterone in 3T3-L1 adipocytes.

Journal of medicinal food 20090801

Dynamic residual complexity of natural products by qHNMR: solution stability of desmethylxanthohumol.

Planta medica 20090601

Fundamentals and health benefits of xanthohumol, a natural product derived from hops and beer.

Natural product communications 20090501

[Determination of xanthohumol in beer by solid-phase extraction-high performance liquid chromatography].

Se pu = Chinese journal of chromatography 20090501

In vitro evaluation of antibacterial, anticollagenase, and antioxidant activities of hop components (Humulus lupulus) addressing acne vulgaris.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20090401

Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells.

Blood 20090226

LC-MS/MS quantitation of hop-derived bitter compounds in beer using the ECHO technique.

Journal of agricultural and food chemistry 20090225

Increased IL-2 production in T cells by xanthohumol through enhanced NF-AT and AP-1 activity.

International immunopharmacology 20090101

Immunomodulatory activity of xanthohumol: inhibition of T cell proliferation, cell-mediated cytotoxicity and Th1 cytokine production through suppression of NF-kappaB.

Immunopharmacology and immunotoxicology 20090101

Xanthohumol influences preadipocyte differentiation: implication of antiproliferative and apoptotic effects.

Journal of agricultural and food chemistry 20081224

Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models.

Xenobiotica; the fate of foreign compounds in biological systems 20081201

Inhibitory effects of xanthohumol from hops (Humulus lupulus L.) on human hepatocellular carcinoma cell lines.

Phytotherapy research : PTR 20081101

Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation.

Molecular cancer therapeutics 20080901

Xanthohumol inhibits inflammatory factor production and angiogenesis in breast cancer xenografts.

Journal of cellular biochemistry 20080801

Synthesis, cytotoxicity, and antioxidative activity of minor prenylated chalcones from Humulus lupulus.

Journal of natural products 20080701

Effect of xanthohumol on melanogenesis in B16 melanoma cells.

Experimental & molecular medicine 20080630

Enhanced effects of xanthohumol plus honokiol on apoptosis in 3T3-L1 adipocytes.

Obesity (Silver Spring, Md.) 20080601

Natural and non-natural prenylated chalcones: synthesis, cytotoxicity and anti-oxidative activity.

Bioorganic & medicinal chemistry 20080415

Differential anti-inflammatory pathway by xanthohumol in IFN-gamma and LPS-activated macrophages.

International immunopharmacology 20080401

Antimutagenicity of hops (Humulus lupulus L.): bioassay-directed fractionation and isolation of xanthohumol.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20080301

Antigenotoxic effect of Xanthohumol in rat liver slices.

Toxicology in vitro : an international journal published in association with BIBRA 20080301

Positive antibacterial co-action between hop (Humulus lupulus) constituents and selected antibiotics.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20080301

Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death.

Phytotherapy research : PTR 20080201

EST analysis of hop glandular trichomes identifies an O-methyltransferase that catalyzes the biosynthesis of xanthohumol.

The Plant cell 20080101

New prenylchalcones from the hops of Humulus lupulus.

Journal of Asian natural products research 20080101

Glycosylation of xanthohumol by fungi.

Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women.

The British journal of nutrition 20071101

AKT/NF-kappaB inhibitor xanthohumol targets cell growth and angiogenesis in hematologic malignancies.

Cancer 20071101

Effect of xanthohumol and isoxanthohumol on 3T3-L1 cell apoptosis and adipogenesis.

Apoptosis : an international journal on programmed cell death 20071101

Inhibition of topoisomerase I activity and efflux drug transporters' expression by xanthohumol. from hops.

Archives of pharmacal research 20071101

Total synthesis of xanthohumol.

Journal of natural products 20070901

Protective effects of xanthohumol against the genotoxicity of benzo(a)pyrene (BaP), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and tert-butyl hydroperoxide (t-BOOH) in HepG2 human hepatoma cells.

Mutation research 20070815

Binding of the hop (Humulus lupulus L.) chalcone xanthohumol to cytosolic proteins in Caco-2 intestinal epithelial cells.

Molecular nutrition & food research 20070701

Analysis of xanthohumol and isoxanthohumol in different hop products by liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry.

Journal of chromatography. A 20070525

Sensitive electrochemical detection method for alpha-acids, beta-acids and xanthohumol in hops (Humulus lupulus L.).

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

Determination of xanthohumol in hops (Humulus lupulus L.) by nonaqueous CE.

Electrophoresis 20070301

Anticoccidial effects of xanthohumol.

Avian diseases 20070301

Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells.

Cancer letters 20070208

Distinct modulation of alkaline phosphatase isoenzymes by 17beta-estradiol and xanthohumol in breast cancer MCF-7 cells.

Clinical biochemistry 20070201

Inhibition of S1P by polyphenols prevents inflammation and angiogenesis: NFkappaB, a downstream effector?

Free radical biology & medicine 20070115

Relevance of organic farming and effect of climatological conditions on the formation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol in hop (Humulus lupulus L.).

Journal of agricultural and food chemistry 20070110

Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20061101

Microbial metabolism of the prenylated chalcone xanthohumol.

Journal of natural products 20061001

Influence of xanthohumol on the binding behavior of GABAA receptors and their lateral mobility at hippocampal neurons.

Planta medica 20060601

Effect of hop (Humulus lupulus L.) flavonoids on aromatase (estrogen synthase) activity.

Journal of agricultural and food chemistry 20060419

Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-kappaB and Akt as targets.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

Antiinvasive effect of xanthohumol, a prenylated chalcone present in hops (Humulus lupulus L.) and beer.

International journal of cancer 20051220

Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice.

Biochemical and biophysical research communications 20051028

Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway.