[[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium hydrate
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Ifenprodil, a NR2B-selective antagonist of NMDA receptor, inhibits reverse Na+/Ca2+ exchanger in neurons. | Neuropharmacology 20121101 |
State-dependent increase of cortical gamma activity during REM sleep after selective blockade of NR2B subunit containing NMDA receptors. | Sleep 20120701 |
NMDARs mediate the role of monoamine oxidase A in pathological aggression. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120620 |
Hippocampus versus entorhinal cortex decoupling by an NR2 subunit-specific block of NMDA receptors in a rat in vitro model of temporal lobe epilepsy. | Epilepsia 20120501 |
NMDA GluN2A and GluN2B receptors play separate roles in the induction of LTP and LTD in the amygdala and in the acquisition and extinction of conditioned fear. | Neuropharmacology 20120201 |
Role of GluN2A and GluN2B subunits in the formation of filopodia and secondary dendrites in cultured hippocampal neurons. | Naunyn-Schmiedeberg's archives of pharmacology 20120201 |
Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures. | Cell calcium 20120201 |
Dopamine induces a GluN2A-dependent form of long-term depression of NMDA synaptic responses in the nucleus accumbens. | Neuropharmacology 20110501 |
Blockade of NR2A-containing NMDA receptors induces Tau phosphorylation in rat hippocampal slices. | Neural plasticity 20100101 |
Differential role of N-methyl-D-aspartate receptor subunits 2A and 2B in mediating phencyclidine-induced perinatal neuronal apoptosis and behavioral deficits. | Neuroscience 20091110 |
Reduced spatial learning in mice treated with NVP-AAM077 through down-regulating neurogenesis. | European journal of pharmacology 20091110 |
N-methyl-D-aspartate-evoked adenosine and inosine release from neurons requires extracellular calcium. | Canadian journal of physiology and pharmacology 20091001 |
Differential roles of NMDA receptor subtypes in ischemic neuronal cell death and ischemic tolerance. | Stroke 20081101 |
NMDA receptor antagonists reveal age-dependent differences in the properties of visual cortical plasticity. | Journal of neurophysiology 20081001 |
Conditioning-strength dependent involvement of NMDA NR2B subtype receptor in the basolateral nucleus of amygdala in acquisition of auditory fear memory. | Neuropharmacology 20080801 |
Differential effect of NR2A and NR2B subunit selective NMDA receptor antagonists on striato-pallidal neurons: relationship to motor response in the 6-hydroxydopamine model of parkinsonism. | Journal of neurochemistry 20080701 |
Amygdala infusions of an NR2B-selective or an NR2A-preferring NMDA receptor antagonist differentially influence fear conditioning and expression in the fear-potentiated startle test. | Learning & memory (Cold Spring Harbor, N.Y.) 20080201 |
Brain-derived neurotrophic factor activation of extracellular signal-regulated kinase is autonomous from the dominant extrasynaptic NMDA receptor extracellular signal-regulated kinase shutoff pathway. | Neuroscience 20080124 |
Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors. | Neuropharmacology 20070701 |
Modular competition driven by NMDA receptor subtypes in spike-timing-dependent plasticity. | Journal of neurophysiology 20070401 |
Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus. | Neuropharmacology 20070101 |
Pharmacological isolation of postsynaptic currents mediated by NR2A- and NR2B-containing NMDA receptors in the anterior cingulate cortex. | Molecular pain 20070101 |
Effects of exercise on NMDA receptor subunit contributions to bidirectional synaptic plasticity in the mouse dentate gyrus. | Hippocampus 20070101 |
Equilibrium constants for (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic acid (NVP-AAM077) acting at recombinant NR1/NR2A and NR1/NR2B N-methyl-D-aspartate receptors: Implications for studies of synaptic transmission. | Molecular pharmacology 20060901 |
Zinc modulates bidirectional hippocampal plasticity by effects on NMDA receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060705 |
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315 |
Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine. | Neuron 20060216 |
Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060201 |
Tonic facilitation of glutamate release by presynaptic NR2B-containing NMDA receptors is increased in the entorhinal cortex of chronically epileptic rats. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111 |
Contribution of NR2A and NR2B NMDA subunits to bidirectional synaptic plasticity in the hippocampus in vivo. | Hippocampus 20060101 |
Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory. | Neuron 20050915 |
Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050720 |
Roles of NMDA receptor NR2A and NR2B subtypes for long-term depression in the anterior cingulate cortex. | The European journal of neuroscience 20050701 |
Synthesis and pharmacology of N1-substituted piperazine-2,3-dicarboxylic acid derivatives acting as NMDA receptor antagonists. | Journal of medicinal chemistry 20050407 |
Selective subunit antagonists suggest an inhibitory relationship between NR2B and NR2A-subunit containing N-methyl-D: -aspartate receptors in hippocampal slices. | Experimental brain research 20050401 |
Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908 |
Structure-activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid. | British journal of pharmacology 20040201 |
5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. | Bioorganic & medicinal chemistry letters 20020408 |
Glucocorticoid rapidly enhances NMDA-evoked neurotoxicity by attenuating the NR2A-containing NMDA receptor-mediated ERK1/2 activation. | Molecular endocrinology (Baltimore, Md.) |