Home Other Building Blocks (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

CAS No.:
104632-26-0
Catalog Number:
AG003CNR
Molecular Formula:
C10H17N3S
Molecular Weight:
211.3271
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$50
- +
5g
98%
In Stock USA
United States
$137
- +
10g
98%
In Stock USA
United States
$219
- +
25g
98%
In Stock USA
United States
$413
- +
Product Description
Catalog Number:
AG003CNR
Chemical Name:
(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
CAS Number:
104632-26-0
Molecular Formula:
C10H17N3S
Molecular Weight:
211.3271
MDL Number:
MFCD00869076
IUPAC Name:
(6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
InChI:
InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1
InChI Key:
FASDKYOPVNHBLU-ZETCQYMHSA-N
SMILES:
CCCN[C@H]1CCc2c(C1)sc(n2)N
EC Number:
600-593-1
UNII:
83619PEU5T
Properties
Complexity:
188  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
211.114g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
211.327g/mol
Monoisotopic Mass:
211.114g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
79.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.9  
Literature
Title Journal
European guidelines on management of restless legs syndrome: report of a joint task force by the European Federation of Neurological Societies, the European Neurological Society and the European Sleep Research Society. European journal of neurology 20121101
ADMET considerations for restless leg syndrome drug treatments. Expert opinion on drug metabolism & toxicology 20121001
Sleep and violence. Current treatment options in neurology 20121001
Strategies for the treatment of restless legs syndrome. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20121001
The role of the dopaminergic system in mood, motivation and cognition in Parkinson's disease: a double blind randomized placebo-controlled experimental challenge with pramipexole and methylphenidate. Journal of the neurological sciences 20120915
Pramipexole-related chronic lower limb oedema in a patient with Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120901
High-affinity and selective dopamine D₃ receptor full agonists. Bioorganic & medicinal chemistry letters 20120901
Spontaneous unwelcome orgasms due to pramipexole and ropinirole. Movement disorders : official journal of the Movement Disorder Society 20120901
Therapies in Parkinson's disease. Current opinion in neurology 20120801
The treatment of restless legs syndrome and periodic limb movement disorder in adults--an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline. Sleep 20120801
Depression in Parkinson's disease: diagnosis and treatment. Arquivos de neuro-psiquiatria 20120801
Pramipexole- and methamphetamine-induced reward-mediated behavior in a rodent model of Parkinson's disease and controls. Behavioural brain research 20120715
Indirect comparisons of adverse events and dropout rates in early Parkinson's disease trials of pramipexole, ropinirole, and rasagiline. The International journal of neuroscience 20120701
Differentiation of enantiomeric drugs by iodo-substituted L-amino acid references under electrospray ionization mass spectrometric conditions. Rapid communications in mass spectrometry : RCM 20120615
Pilot randomized, controlled trial of pramipexole to augment antipsychotic treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120601
Effects of acute pramipexole on male rats' preference for gambling-like rewards II. Experimental and clinical psychopharmacology 20120601
Reversible antecollis associated with pramipexole in a patient with Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120601
Midbrain tremor: a tremor resistant to treatment. Acta neurologica Belgica 20120601
Finasteride attenuates pathological gambling in patients with Parkinson disease. Journal of clinical psychopharmacology 20120601
Dopamine dysregulation syndrome including mania related to coadministration of droxidopa. Journal of clinical psychopharmacology 20120601
Dissociation of periodic leg movements from arousals in restless legs syndrome. Annals of neurology 20120601
Initiatives to improve prescribing efficiency for drugs to treat Parkinson's disease in Croatia: influence and future directions. Expert review of pharmacoeconomics & outcomes research 20120601
Anhedonia in Japanese patients with Parkinson's disease: analysis using the Snaith-Hamilton Pleasure Scale. Clinical neurology and neurosurgery 20120501
Pramipexole-induced increased probabilistic discounting: comparison between a rodent model of Parkinson's disease and controls. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120501
Leg movements during wakefulness in restless legs syndrome: time structure and relationships with periodic leg movements during sleep. Sleep medicine 20120501
Dopamine agonist-induced penile erection and yawning: differential role of D₂-like receptor subtypes and correlation with nitric oxide production in the paraventricular nucleus of the hypothalamus of male rats. Behavioural brain research 20120501
Neural stem cell niches in health and diseases. Current pharmaceutical design 20120501
A multicenter randomized placebo-controlled clinical trial of pramipexole for Tourette's syndrome. Movement disorders : official journal of the Movement Disorder Society 20120501
Drug safety evaluation of rotigotine. Expert opinion on drug safety 20120501
[Othello syndrome induced by pramipexole]. Revista de neurologia 20120416
Photo-degradation products of pramipexole. Bioorganic & medicinal chemistry letters 20120415
An upper limb variant of RLS? Report of 2 cases. Clinical neurology and neurosurgery 20120401
In vivo mesolimbic D2/3 receptor binding predicts posttherapeutic clinical responses in restless legs syndrome: a positron emission tomography study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120401
Burning mouth syndrome in Parkinson's disease: dopamine as cure or cause? The journal of headache and pain 20120401
Dopamine agonists in dihydropteridine reductase deficiency. Molecular genetics and metabolism 20120401
[Disinhibitory abnormal behavior induced by treatment of Parkinson disease]. Brain and nerve = Shinkei kenkyu no shinpo 20120401
[Fatigue and weight loss in Parkinson's disease]. Brain and nerve = Shinkei kenkyu no shinpo 20120401
Modeling mitochondrial dysfunctions in the brain: from mice to men. Journal of inherited metabolic disease 20120301
Long-term administration of the dopamine D3/2 receptor agonist pramipexole increases dopamine and serotonin neurotransmission in the male rat forebrain. Journal of psychiatry & neuroscience : JPN 20120301
The effect of dopamine agonists on adaptive and aberrant salience in Parkinson's disease. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120301
The risk of new onset heart failure associated with dopamine agonist use in Parkinson's disease. Pharmacological research 20120301
Evaluation of periodic limb movements in a putative animal model of restless leg syndrome. Movement disorders : official journal of the Movement Disorder Society 20120301
CART peptide in the nucleus accumbens shell acts downstream to dopamine and mediates the reward and reinforcement actions of morphine. Neuropharmacology 20120301
The abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and mitochondrial integrity. Neurobiology of disease 20120301
Novel extraction technique to remove a penile constriction device. The journal of sexual medicine 20120301
Effectiveness of pramipexole, a dopamine agonist, on rapid eye movement sleep behavior disorder. The Tohoku journal of experimental medicine 20120301
Pramipexole is active in depression tests and modulates monoaminergic transmission, but not brain levels of BDNF in mice. European journal of pharmacology 20120227
Stereochemical and neuroanatomical selectivity of pramipexole effects on sensorimotor gating in rats. Brain research 20120209
Breakthrough symptoms during the daytime in patients with restless legs syndrome (Willis-Ekbom disease). Sleep medicine 20120201
Effects of pramipexole on the reinforcing effectiveness of stimuli that were previously paired with cocaine reinforcement in rats. Psychopharmacology 20120101
Effect of pramipexole on cutaneous-silent-period parameters in patients with restless legs syndrome. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20120101
Dopamine agonists and ischemic complications in Parkinson's disease: a nested case-control study. European journal of clinical pharmacology 20120101
Outcomes from switching from rotigotine patch to alternate therapies in Parkinson's disease. The International journal of neuroscience 20120101
Dopamine agonist use and the risk of heart failure. Pharmacoepidemiology and drug safety 20120101
Efficacy and safety of pramipexole in chinese patients with restless legs syndrome: results from a multi-center, randomized, double-blind, placebo-controlled trial. Sleep medicine 20120101
Placebo-controlled adjunctive trial of pramipexole in patients with bipolar disorder: targeting cognitive dysfunction. The Journal of clinical psychiatry 20120101
Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas. Clinical schizophrenia & related psychoses 20120101
Adenosine A(2A) Receptor Antagonists Do Not Disrupt Rodent Prepulse Inhibition: An Improved Side Effect Profile in the Treatment of Parkinson's Disease. Parkinson's disease 20120101
Impact of anxiety on quality of life in Parkinson's disease. Parkinson's disease 20120101
The dopamine augmenter L-DOPA does not affect positive mood in healthy human volunteers. PloS one 20120101
The neuroprotective disease-modifying potential of psychotropics in Parkinson's disease. Parkinson's disease 20120101
A combination of dopamine genes predicts success by professional Wall Street traders. PloS one 20120101
Risk of falls in Parkinson's disease: a cross-sectional study of 160 patients. Parkinson's disease 20120101
Patient considerations in early management of Parkinson's disease: focus on extended-release pramipexole. Patient preference and adherence 20120101
Pramipexole may be an effective treatment option in essential tremor. Clinical neuropharmacology 20120101
Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial. BMJ open 20120101
Computed three-dimensional atlas of subthalamic nucleus and its adjacent structures for deep brain stimulation in Parkinson's disease. ISRN neurology 20120101
Restless leg syndrome, periodic limb movements, febrile seizures and Attention deficit hyperactivity disorder in an Indian family. Annals of Indian Academy of Neurology 20120101
Levodopa in combination with carbidopa does not affect plasma arginine vasopressin levels in treatment-naïve older patients with Parkinson's disease: A before-after study. Neuro endocrinology letters 20120101
The Effects of a Gentle Yoga Program on Sleep, Mood, and Blood Pressure in Older Women with Restless Legs Syndrome (RLS): A Preliminary Randomized Controlled Trial. Evidence-based complementary and alternative medicine : eCAM 20120101
Successful treatment with clonazepam and pramipexole of a patient with sleep-related eating disorder associated with restless legs syndrome: a case report. Case reports in medicine 20120101
Dyskinesias and treatment with pramipexole in patients with Parkinson's disease. Parkinson's disease 20120101
Role and clinical utility of pramipexole extended release in the treatment of early Parkinson's disease. Clinical interventions in aging 20120101
Nightmare-enacting behavior responding to zonisamide in early Parkinson's disease. Case reports in neurology 20120101
A deleterious mutation in DNAJC6 encoding the neuronal-specific clathrin-uncoating co-chaperone auxilin, is associated with juvenile parkinsonism. PloS one 20120101
Boomerang sign: Clinical significance of transient lesion in splenium of corpus callosum. Annals of Indian Academy of Neurology 20120101
Dopamine agonists and pathologic behaviors. Parkinson's disease 20120101
Role of gabapentin enacarbil XR in restless legs syndrome. Therapeutics and clinical risk management 20120101
Huntington's disease. Handbook of clinical neurology 20120101
Theranostic liposomes loaded with quantum dots and apomorphine for brain targeting and bioimaging. International journal of nanomedicine 20120101
Treatment-resistant Schizophrenia: Evidence-based Strategies. Mens sana monographs 20120101
Increased Orbitofrontal Brain Activation after Administration of a Selective Adenosine A(2A) Antagonist in Cocaine Dependent Subjects. Frontiers in psychiatry 20120101
Cognitive impairment and dementia in Parkinson's disease: clinical features, diagnosis, and management. Frontiers in neurology 20120101
Reviewing two types of addiction - pathological gambling and substance use. Indian journal of psychological medicine 20120101
Parallel appearance of compulsive behaviors and artistic creativity in Parkinson's disease. Case reports in neurology 20120101
Bipolar disorder: clinical perspectives and implications with cognitive dysfunction and dementia. Depression research and treatment 20120101
Clinical aspects and management of levodopa-induced dyskinesia. Parkinson's disease 20120101
A tribute to charlie chaplin: induced positive affect improves reward-based decision-learning in Parkinson's disease. Frontiers in psychology 20120101
Efficacy and safety of extended- versus immediate-release pramipexole in Japanese patients with advanced and L-dopa-undertreated Parkinson disease: a double-blind, randomized trial. Clinical neuropharmacology 20120101
The efficacy of pramipexole, a dopamine receptor agonist, as an adjunctive treatment in treatment-resistant depression: an open-label trial. TheScientificWorldJournal 20120101
The effect of pramipexole therapy on balance disorder and fall risk in Parkinson's disease at early stage: clinical and posturographic assessment. ISRN neurology 20120101
Pramipexole upregulates dopamine receptor D₂ and D₃ expression in rat striatum. Journal of pharmacological sciences 20120101
An eight component decision-making model for problem gambling: a systems approach to stimulate integrative research. Journal of gambling studies 20111201
Temporal stability of the Unified Dyskinesia Rating Scale. Movement disorders : official journal of the Movement Disorder Society 20111201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
New dopamine agonist pramipexole improves parkinsonism and depression in Parkinson's disease. Hiroshima journal of medical sciences 20111201
Dopamine D2-like receptor agonists induce penile erection in male rats: differential role of D2, D3 and D4 receptors in the paraventricular nucleus of the hypothalamus. Behavioural brain research 20111120
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis. Nature medicine 20111120
Effect of chronic kidney disease on excessive daytime sleepiness in Parkinson disease. European journal of neurology 20111101
Impulse control disorders in Parkinson's disease: seeking a roadmap toward a better understanding. Brain structure & function 20111101
Prescribed drugs and violence: a case/noncase study in the French PharmacoVigilance Database. European journal of clinical pharmacology 20111101
Development and validation of a chiral capillary electrophoresis method for assay and enantiomeric purity control of pramipexole. Journal of separation science 20111101
Restless legs syndrome in subjects with a knee prosthesis: evidence that symptoms are generated in the periphery. Clinics (Sao Paulo, Brazil) 20111101
Response perseveration in stimulant dependence is associated with striatal dysfunction and can be ameliorated by a D(2/3) receptor agonist. Biological psychiatry 20111015
Dopamine D1/5 and D2/3 agonists differentially attenuate somatic signs of nicotine withdrawal in rats. Pharmacology, biochemistry, and behavior 20111001
Disparate effects of pramipexole on locomotor activity and sensorimotor gating in Sprague-Dawley rats. Pharmacology, biochemistry, and behavior 20111001
Pharmacokinetic evaluation of pramipexole. Expert opinion on drug metabolism & toxicology 20111001
Pharmacological evaluation of the adequacy of marble burying as an animal model of compulsion and/or anxiety. Behavioural pharmacology 20111001
Treatment of Parkinson's disease. Psychological disorders: striking a balance in order to optimise antiparkinsonian treatment. Prescrire international 20111001
The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the motor symptoms of Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20111001
The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the non-motor symptoms of Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20111001
Electrode position and the clinical outcome after bilateral subthalamic nucleus stimulation. Journal of Korean medical science 20111001
Restless abdomen: a phenotypic variant of restless legs syndrome. Neurology 20110927
Functional potencies of dopamine agonists and antagonists at human dopamine D₂ and D₃ receptors. European journal of pharmacology 20110901
Acupuncture for restless legs syndrome in patients previously treated with dopaminergic drugs. Acupuncture in medicine : journal of the British Medical Acupuncture Society 20110901
Pramipexole extended release in Parkinson's disease. Expert review of neurotherapeutics 20110901
Comparison of weight changes following unilateral and staged bilateral STN DBS for advanced PD. Brain and behavior 20110901
Extended-release pramipexole in advanced Parkinson disease: a randomized controlled trial. Neurology 20110823
Extended-release pramipexole in early Parkinson disease: a 33-week randomized controlled trial. Neurology 20110823
Executive control in Parkinson's disease: effects of dopaminergic medication and deep brain stimulation on anti-cue keypress performance. Neuroscience letters 20110815
Safety, tolerability, and pharmacokinetics of KNS-760704 (dexpramipexole) in healthy adult subjects. Journal of clinical pharmacology 20110801
Pathological gambling plus hypersexuality in restless legs syndrome: a new case. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110801
Migraine and restless legs syndrome: is there an association? The journal of headache and pain 20110801
Effects of selective dopaminergic compounds on a delay-discounting task. Behavioural pharmacology 20110801
Rotigotine transdermal patch: a review of its use in the treatment of Parkinson's disease. CNS drugs 20110801
Disease modification in Parkinson's disease. Drugs & aging 20110801
Pathological behaviors provoked by dopamine agonist therapy of Parkinson's disease. Physiology & behavior 20110725
Preferential D2 or preferential D3 dopamine agonists in restless legs syndrome. Neurology 20110712
Dopaminergic drugs and the risk of hip or femur fracture: a population-based case-control study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110701
Anhedonia in Japanese patients with Parkinson's disease. Geriatrics & gerontology international 20110701
Reward processing abnormalities in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20110701
Pardoprunox in early Parkinson's disease: results from 2 large, randomized double-blind trials. Movement disorders : official journal of the Movement Disorder Society 20110701
Pramipexole for the treatment of early Parkinson's disease. Expert review of neurotherapeutics 20110701
Treatment in late Parkinson's disease. Annals of Indian Academy of Neurology 20110701
Motor fluctuations and dyskinesias (diagnosis and management). Annals of Indian Academy of Neurology 20110701
Psychosis in Parkinson's disease. Annals of Indian Academy of Neurology 20110701
Initiation of treatment in early PD (evidences based). Annals of Indian Academy of Neurology 20110701
Treatment-resistant sensory motor symptoms in persons with SCI may be signs of restless legs syndrome. Spinal cord 20110601
Behavioral sensitization to cocaine in rats: evidence for temporal differences in dopamine D3 and D2 receptor sensitivity. Psychopharmacology 20110601
Alterations in pain responses in treated and untreated patients with restless legs syndrome: associations with sleep disruption. Sleep medicine 20110601
Induction and expression of abnormal involuntary movements is related to the duration of dopaminergic stimulation in 6-OHDA-lesioned rats. The European journal of neuroscience 20110601
Therapies for dopaminergic-induced dyskinesias in Parkinson disease. Annals of neurology 20110601
Medical management of Parkinson's disease: focus on neuroprotection. Current neuropharmacology 20110601
Neural mechanisms of antidepressant efficacy of the dopamine receptor agonist pramipexole in treatment of bipolar depression. The international journal of neuropsychopharmacology 20110501
A 10-year, longitudinal assessment of dopamine agonists and methadone in the treatment of restless legs syndrome. Sleep medicine 20110501
Distinct effects of pramipexole on the proliferation of adult mouse sub-ventricular zone-derived cells and the appearance of a neuronal phenotype. Neuropharmacology 20110501
Dopamine agonist-triggered pathological behaviors: surveillance in the PD clinic reveals high frequencies. Parkinsonism & related disorders 20110501
Utilization of anti-Parkinson drugs in Australia: 1995-2009. Pharmacoepidemiology and drug safety 20110501
Pramipexole modulates the neural network of reward anticipation. Human brain mapping 20110501
Restless legs syndrome (RLS) augmentation associated with dopamine agonist and levodopa usage in a community sample. Sleep medicine 20110501
Milestones in Parkinson's disease therapeutics. Movement disorders : official journal of the Movement Disorder Society 20110501
Development and validation of GC/MS method for determination of pramipexole in rat plasma. Biomedical chromatography : BMC 20110401
Peripheral biomarkers of cognitive response to dopamine receptor agonist treatment. Psychopharmacology 20110401
The first case of a 'jumping stump' syndrome in a lower limb amputee responding to pramipexole. European journal of neurology 20110401
Efficacy and augmentation during 6 months of double-blind pramipexole for restless legs syndrome. Sleep medicine 20110401
Adjunctive treatment with low-dosage pramipexole for risperidone-associated hyperprolactinemia and sexual dysfunction in a male patient with schizophrenia. Journal of clinical psychopharmacology 20110401
Pramipexole versus ropinirole: polysomnographic acute effects in restless legs syndrome. Movement disorders : official journal of the Movement Disorder Society 20110401
Tinnitus control by dopamine agonist pramipexole in presbycusis patients: a randomized, placebo-controlled, double-blind study. The Laryngoscope 20110401
[Adverse effect of Sifrol or not?]. Lakartidningen 20110401
Dopamine agonists for restless legs syndrome. The Cochrane database of systematic reviews 20110316
Pharmacotherapy for the treatment of acute bipolar II depression: current evidence. The Journal of clinical psychiatry 20110301
Sleep disorders in patients with traumatic brain injury: a review. CNS drugs 20110301
Drugs and drug delivery in PD: optimizing control of symptoms with pramipexole prolonged-release. European journal of neurology 20110301
Treatment of depressive symptoms in Parkinson's disease. European journal of neurology 20110301
Hemiparkinsonism-hemiatrophy syndrome. Archives of Iranian medicine 20110301
Depressogenic effects of medications: a review. Dialogues in clinical neuroscience 20110301
Levodopa for restless legs syndrome. The Cochrane database of systematic reviews 20110216
The effect of pramipexole on depressive symptoms in Parkinson's disease. The Kobe journal of medical sciences 20110202
OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users. Neurogenetics 20110201
Evaluation of painful sensory symptoms in restless legs syndrome: experience from two clinical trials. Sleep medicine 20110201
Cost effectiveness of rasagiline and pramipexole as treatment strategies in early Parkinson's disease in the UK setting: An economic Markov model evaluation. Drugs & aging 20110201
Effects of acute pramipexole on preference for gambling-like schedules of reinforcement in rats. Psychopharmacology 20110101
Effects of acute dopamine-agonist treatment in restless legs syndrome on heart rate variability during sleep. Sleep medicine 20110101
Twice-daily, low-dose pramipexole in early Parkinson's disease: a randomized, placebo-controlled trial. Movement disorders : official journal of the Movement Disorder Society 20110101
Randomized trial of pramipexole for patients with restless legs syndrome (RLS) and RLS-related impairment of mood. Sleep medicine 20110101
Serotonin and dopamine play complementary roles in gambling to recover losses. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110101
Differential induction of adenylyl cyclase supersensitivity by antiparkinson drugs acting as agonists at dopamine D1/D2/D3 receptors vs D2/D3 receptors only: parallel observations from co-transfected human and native cerebral receptors. Neuropharmacology 20110101
The long-term effects of the dopamine agonist pramipexole in a proposed restless legs syndrome animal model. Sleep medicine 20110101
Efficacy, safety and dose-response of pramipexole in Japanese patients with primary restless legs syndrome: randomized trial. Neuropsychobiology 20110101
A meta-analysis of pain response in the treatment of fibromyalgia. Pain practice : the official journal of World Institute of Pain 20110101
[Possibilities and limitations of psychopharmacological treatments in patients with psychological comorbidity]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 20110101
Pathological gambling in a bipolar patient treated with pramipexole. The Journal of neuropsychiatry and clinical neurosciences 20110101
Rotigotine effects on early morning motor function and sleep in Parkinson's disease: a double-blind, randomized, placebo-controlled study (RECOVER). Movement disorders : official journal of the Movement Disorder Society 20110101
Algorithms for the diagnosis and treatment of restless legs syndrome in primary care. BMC neurology 20110101
Adenosine A(2A) receptors measured with [C]TMSX PET in the striata of Parkinson's disease patients. PloS one 20110101
New thoughts on thought disorders in Parkinson's disease: review of current research strategies and challenges. Parkinson's disease 20110101
Increased plasma arginine vasopressin levels in dopamine agonist-treated Parkinson's disease patients. Neuro endocrinology letters 20110101
Binding of pramipexole to extrastriatal dopamine D2/D3 receptors in the human brain: a positron emission tomography study using 11C-FLB 457. PloS one 20110101
Differential effects of dopaminergic therapies on dorsal and ventral striatum in Parkinson's disease: implications for cognitive function. Parkinson's disease 20110101
FTLD-TDP with motor neuron disease, visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases. BMC neurology 20110101
Predicting drug side-effect profiles: a chemical fragment-based approach. BMC bioinformatics 20110101
Dopamine-induced nonmotor symptoms of Parkinson's disease. Parkinson's disease 20110101
Available and emerging treatments for Parkinson's disease: a review. Drug design, development and therapy 20110101
Noradrenaline and Parkinson's disease. Frontiers in systems neuroscience 20110101
Nondrug-related aspect of treating Ekbom disease, formerly known as restless legs syndrome. Neuropsychiatric disease and treatment 20110101
Once-daily pramipexole for the treatment of early and advanced idiopathic Parkinson's disease: implications for patients. Neuropsychiatric disease and treatment 20110101
Sleep Duration and 'on' Time during Different Periods of the Day and Night in Patients with Advanced Parkinson's Disease Receiving Adjunctive Ropinirole Prolonged Release. Parkinson's disease 20110101
Visual symptoms in Parkinson's disease. Parkinson's disease 20110101
Neurobiology of depression and anxiety in Parkinson's disease. Parkinson's disease 20110101
Agonist-specific voltage sensitivity at the dopamine D2S receptor--molecular determinants and relevance to therapeutic ligands. Neuropharmacology 20110101
Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression. PloS one 20110101
Pharmacological and physiological characterization of the tremulous jaw movement model of parkinsonian tremor: potential insights into the pathophysiology of tremor. Frontiers in systems neuroscience 20110101
Pharmacotherapy for fibromyalgia. Frontiers in pharmacology 20110101
Enhanced catecholamine transporter binding in the locus coeruleus of patients with early Parkinson disease. BMC neurology 20110101
Case control polysomnographic studies of sleep disorders in Parkinson's disease. PloS one 20110101
Overnight switch from ropinirole to transdermal rotigotine patch in patients with Parkinson disease. BMC neurology 20110101
Sleep disturbances associated with Parkinson's disease. Parkinson's disease 20110101
Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation. Frontiers in neuroanatomy 20110101
Modulation of human time processing by subthalamic deep brain stimulation. PloS one 20110101
Controversies in neurology: why monoamine oxidase B inhibitors could be a good choice for the initial treatment of Parkinson's disease. BMC neurology 20110101
Psychopharmacological neuroprotection in neurodegenerative diseases, part III: criteria-based assessment: a report of the ANPA committee on research. The Journal of neuropsychiatry and clinical neurosciences 20110101
Panic attack-like episodes possibly induced by pramipexole in a patient with young-onset Parkinson's disease. The Journal of neuropsychiatry and clinical neurosciences 20110101
Frequency of impulse control behaviours associated with dopaminergic therapy in restless legs syndrome. BMC neurology 20110101
Pramipexole reduces the prevalence of fatigue in patients with Parkinson's disease. Internal medicine (Tokyo, Japan) 20110101
Dopaminergic drug-induced modulation of the expression of the dopamine transporter in peripheral blood lymphocytes in Parkinson's disease. Pharmacological reports : PR 20110101
Management of bipolar depression. Indian journal of psychological medicine 20110101
Pramipexole versus dual release levodopa in restless legs syndrome: a double blind, randomised, cross-over trial. Swiss medical weekly 20110101
nardosinane-type sesquiterpenoids from the formosan soft coral Paralemnalia thyrsoides. Marine drugs 20110101
Dopamine dysregulation syndrome and deep brain stimulation of the subthalamic nucleus in Parkinson's disease. Neurology research international 20110101
Sentence comprehension and its association with executive functions in patients with Parkinson's disease. Parkinson's disease 20110101
Bipolar affective disorder and Parkinson's disease. Case reports in medicine 20110101
Cognitive rehabilitation in Parkinson's disease: evidence from neuroimaging. Frontiers in neurology 20110101
Liposomes for Targeted Delivery of Active Agents against Neurodegenerative Diseases (Alzheimer's Disease and Parkinson's Disease). Journal of drug delivery 20110101
Pregnancy in multiple system atrophy: a case report. Journal of medical case reports 20110101
Pramipexole-induced peripheral edema in a patient with bipolar depression. The Journal of neuropsychiatry and clinical neurosciences 20110101
A role for locus coeruleus in Parkinson tremor. Frontiers in human neuroscience 20110101
Proton magnetic resonance spectroscopy in depression. Indian journal of psychiatry 20110101
Periodic Limbic Movement Disorder during Sleep as Diabetes-Related Syndrome? A Polysomnographic Study. ISRN endocrinology 20110101
Apathy and anhedonia in Parkinson's disease. ISRN neurology 20110101
Exercise dependence induced by pramipexole in Parkinson's Disease-a case report. Movement disorders : official journal of the Movement Disorder Society 20101215
Stability studies and structural characterization of pramipexole. Journal of pharmaceutical and biomedical analysis 20101201
Levodopa and pramipexole effects on presynaptic dopamine PET markers and estimated dopamine release. European journal of nuclear medicine and molecular imaging 20101201
Pramipexole for stage 2 treatment-resistant major depression: an open study. Progress in neuro-psychopharmacology & biological psychiatry 20101201
Dopamine agonists and Othello's syndrome. Parkinsonism & related disorders 20101201
Dexpramipexole, the R(+) enantiomer of pramipexole, for the potential treatment of amyotrophic lateral sclerosis. IDrugs : the investigational drugs journal 20101201
Seniors with Parkinson's disease: initial medical treatment. Journal of clinical neurology (Seoul, Korea) 20101201
Successful drug development despite adverse preclinical findings part 2: examples. Journal of toxicologic pathology 20101201
Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study. The Lancet. Neurology 20101126
Randomized, double-blind, multicenter evaluation of pramipexole extended release once daily in early Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20101115
From the cell to the clinic: a comparative review of the partial D₂/D₃receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease. Pharmacology & therapeutics 20101101
Dopamine receptor agonists for the treatment of early or advanced Parkinson's disease. CNS drugs 20101101
Validated ultra-performance liquid chromatography tandem mass spectrometry method for the determination of pramipexole in human plasma. Journal of chromatographic science 20101101
The role of pramipexole in a severe Parkinson's disease model in mice. Therapeutic advances in neurological disorders 20101101
Efficacy, safety, and tolerability of overnight switching from immediate- to once daily extended-release pramipexole in early Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20101030
Toxicity assessment of pramipexole in juvenile rhesus monkeys. Toxicology 20101029
Neuroprotection of pramipexole in UPS impairment induced animal model of Parkinson's disease. Neurochemical research 20101001
Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation. Psychopharmacology 20101001
Role of pramipexole in the management of Parkinson's disease. CNS drugs 20101001
Hypotension and bradycardia associated with concomitant tizanidine and lisinopril therapy. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101001
Differential pharmacological responses of catatonia-like signs in frontotemporal dementia. Neurocase 20101001
[Dopaminergic neuroprotection and reconstruction of neural network tiara]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101001
Clozapine for medication-related pathological gambling in Parkinson disease. Movement disorders : official journal of the Movement Disorder Society 20100915
Adverse drug reactions to dopamine agonists: a comparative study in the French Pharmacovigilance Database. Movement disorders : official journal of the Movement Disorder Society 20100915
Long-term use of pramipexole in bipolar depression: a naturalistic retrospective chart review. The Psychiatric quarterly 20100901
Isolated delusional syndrome in Parkinson's Disease. Parkinsonism & related disorders 20100901
An interaction between levodopa and enteral nutrition resulting in neuroleptic malignant-like syndrome and prolonged ICU stay. The Annals of pharmacotherapy 20100901
Pramipexole extended-release (once-daily formulation) for the treatment of Parkinson's disease. Expert opinion on pharmacotherapy 20100901
Recurrence of cluster headache with pramipexole. Acta neurologica Belgica 20100901
Rationale for delayed-start study of pramipexole in Parkinson's disease: the PROUD study. Movement disorders : official journal of the Movement Disorder Society 20100815
Uptake of pramipexole by human organic cation transporters. Molecular pharmaceutics 20100802
Drug therapies for Parkinson's disease: A database analysis of patient compliance and persistence. The American journal of geriatric pharmacotherapy 20100801
Drug safety monitoring in patients of movement disorders of a tertiary care hospital. Indian journal of pharmacology 20100801
Long-term open-label study of pramipexole in patients with primary restless legs syndrome. Journal of the neurological sciences 20100715
Continuous dopaminergic stimulation by pramipexole is effective to treat early morning akinesia in animal models of Parkinson's disease: A pharmacokinetic-pharmacodynamic study using in vivo microdialysis in rats. Synapse (New York, N.Y.) 20100701
Trials of neuroprotective therapies for Parkinson's disease: problems and limitations. Parkinsonism & related disorders 20100701
Transdermal rotigotine for the perioperative management of Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996) 20100701
Bipolar disorder: an update. Postgraduate medicine 20100701
Coexisting huntingtin and SCA8 repeat expansion: case report of a severe complex neurodegenerative syndrome. Journal of the neurological sciences 20100615
Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade. Experimental neurology 20100601
Parametric approaches towards understanding the effects of the preferential D3 receptor agonist pramipexole on prepulse inhibition in rats. Pharmacology, biochemistry, and behavior 20100601
Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder. CNS neuroscience & therapeutics 20100601
Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial. The Lancet. Neurology 20100601
Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial. The Lancet. Neurology 20100601
Pramipexole for depression and motor symptoms in Parkinson's disease: can we kill two birds with one stone? The Lancet. Neurology 20100601
Influence of compulsivity of drug abuse on dopaminergic modulation of attentional bias in stimulant dependence. Archives of general psychiatry 20100601
Effects of pramipexole on impulsive choice in male wistar rats. Experimental and clinical psychopharmacology 20100601
Acute dopamine-agonist treatment in restless legs syndrome: effects on sleep architecture and NREM sleep instability. Sleep 20100601
Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents. Experimental neurobiology 20100601
[Clinical studies on pramipexol retard]. Ideggyogyaszati szemle 20100530
Dopaminergic challenges in social anxiety disorder: evidence for dopamine D3 desensitisation following successful treatment with serotonergic antidepressants. Journal of psychopharmacology (Oxford, England) 20100501
[Management of restless legs syndrome]. Presse medicale (Paris, France : 1983) 20100501
Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients. Archives of neurology 20100501
Proposed dose equivalence between clonazepam and pramipexole in patients with restless legs syndrome. Progress in neuro-psychopharmacology & biological psychiatry 20100416
Dopamine agonist induced compulsive eating behaviour in a Parkinson's disease patient. Pharmacy world & science : PWS 20100401
Impulsive smoking in a patient with Parkinson's disease treated with dopamine agonists. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100401
Pramipexole extended release: in Parkinson's disease. CNS drugs 20100401
[Pathologic gambling as an adverse effect of the treatment for Parkinson's disease]. Revista medica de Chile 20100401
Compulsive habits in restless legs syndrome patients under dopaminergic treatment. Journal of the neurological sciences 20100315
Patent watch. Nature reviews. Drug discovery 20100301
[Clinical data of the prolonged-release formulation of ropinirole]. Fortschritte der Neurologie-Psychiatrie 20100301
The effects of pramipexole on prepulse inhibition and locomotor activity in C57BL/6J mice. Behavioural pharmacology 20100301
Use of the D2/D3 receptor agonist pramipexole in treatment of rapid-cycling bipolar disorder in an elderly patient. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20100301
Parkinson's disease: health-related quality of life, economic cost, and implications of early treatment. The American journal of managed care 20100301
Othello syndrome in patients with Parkinson's disease. Psychiatria Danubina 20100301
Pramipexole combined with levodopa improves motor function but reduces dyskinesia in MPTP-treated common marmosets. Movement disorders : official journal of the Movement Disorder Society 20100215
Best practice guide for the treatment of REM sleep behavior disorder (RBD). Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20100215
Progressive development of augmentation during long-term treatment with levodopa in restless legs syndrome: results of a prospective multi-center study. Journal of neurology 20100201
Dopamine D2-D3 receptor heteromers: pharmacological properties and therapeutic significance. Current opinion in pharmacology 20100201
Successful treatment of restless legs syndrome with the herbal prescription Yokukansan. Progress in neuro-psychopharmacology & biological psychiatry 20100201
LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor. Psychopharmacology 20100201
Population in vitro-in vivo correlation model for pramipexole slow-release oral formulations. Pharmaceutical research 20100201
Tolerability and safety of ropinirole versus other dopamine agonists and levodopa in the treatment of Parkinson's disease: meta-analysis of randomized controlled trials. Drug safety 20100201
Randomized trials of dopamine agonists in restless legs syndrome: a systematic review, quality assessment, and meta-analysis. Clinical therapeutics 20100201
Decision-making during gambling: an integration of cognitive and psychobiological approaches. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20100127
Zolpidem-induced sleep-related eating disorder. Journal of the neurological sciences 20100115
Changes of cortical excitability after dopaminergic treatment in restless legs syndrome. Sleep medicine 20100101
Effect of apomorphine on cognitive performance and sensorimotor gating in humans. Psychopharmacology 20100101
Orally disintegrating selegiline in Parkinson patients with dopamine agonist-related adverse effects. Clinical neuropharmacology 20100101
Impulse control disorder and piribedil: report of 5 cases. Clinical neuropharmacology 20100101
Efficacy and safety of pramipexole in Japanese patients with primary restless legs syndrome: A polysomnographic randomized, double-blind, placebo-controlled study. Sleep medicine 20100101
Why do some promising brain-stimulation devices fail the next steps of clinical development? Expert review of medical devices 20100101
Effects of a dopamine agonist on the pharmacodynamics of levodopa in Parkinson disease. Archives of neurology 20100101
Impulse control disorders with the use of dopaminergic agents in restless legs syndrome: a case-control study. Sleep 20100101
Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole. BMC pharmacology 20100101
Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data. The Journal of neuropsychiatry and clinical neurosciences 20100101
[Effect of dopamine agonist pramipexole (mirapex) on tremor, affective disorders and quality of life in patients with Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
Delusion of Cotard's syndrome successfully treated with a dopamine agonist. The Journal of neuropsychiatry and clinical neurosciences 20100101
Impact of dopamine agonists on compulsive behaviors: a case series of pramipexole-induced pathological gambling. Psychosomatics 20100101
Gabapentin enacarbil - clinical efficacy in restless legs syndrome. Neuropsychiatric disease and treatment 20100101
[Effects of the dopamine agonist mirapex (pramipexole) therapy on sleep disorders in Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
Efficacy and acceptability of selective serotonin reuptake inhibitors for the treatment of depression in Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials. BMC neurology 20100101
Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management. Neuropsychiatric disease and treatment 20100101
Carbidopa/levodopa/entacapone: the evidence for its place in the treatment of Parkinson's disease. Core evidence 20100101
Use of near-infrared light to reduce symptoms associated with restless legs syndrome in a woman: a case report. Journal of medical case reports 20100101
Remission of severe restless legs syndrome and periodic limb movements in sleep after bilateral excision of multiple foot neuromas: a case report. Journal of medical case reports 20100101
Levodopa in the treatment of Parkinson's disease: an old drug still going strong. Clinical interventions in aging 20100101
Therapeutic interventions and adjustments in the management of Parkinson disease: role of combined carbidopa/levodopa/entacapone (Stalevo). Neuropsychiatric disease and treatment 20100101
Circadian rhythm disturbances in patients with Alzheimer's disease: a review. International journal of Alzheimer's disease 20100101
Treatment of moderate to severe restless legs syndrome: 2-year safety and efficacy of rotigotine transdermal patch. BMC neurology 20100101
Validation of a column liquid chromatographic method for the analysis of pramipexole and its five impurities. Journal of AOAC International 20100101
The Impact of Clinical and Cognitive Variables on Social Functioning in Parkinson's Disease: Patient versus Examiner Estimates. Parkinson's disease 20100101
Dopaminergic treatment in idiopathic restless legs syndrome: effects on subjective sleepiness. Clinical neuropharmacology 20100101
Extrastriatal dopaminergic circuits of the Basal Ganglia. Frontiers in neuroanatomy 20100101
Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys. PloS one 20100101
Pramipexole extended release: a novel treatment option in Parkinson's disease. Parkinson's disease 20100101
Effect of bromocriptine on the severity of ovarian hyperstimulation syndrome and outcome in high responders undergoing assisted reproduction. Journal of human reproductive sciences 20100101
Synthesis, Characterization, and Biological Evaluation of certain 6-methyl-2(3H)-benzo-1, 3-thiazolyl-1'-ethylidene-2-(o, p- Substituted Acetophenones) Hydrazine Analogs. Journal of young pharmacists : JYP 20100101
Pharmacotherapy in the management of early Parkinson's disease: cost-effectiveness and patient acceptability. ClinicoEconomics and outcomes research : CEOR 20100101
Pathological gambling from dopamine agonist and deep brain stimulation of the nucleus tegmenti pedunculopontine. BMJ case reports 20100101
Nonmotor symptoms in de novo Parkinson disease before and after dopaminergic treatment. Journal of the neurological sciences 20091215
Dopamine agonist-induced antecollis in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20091215
Pramipexole and gender identity disorder: expanding the phenotype of hypersexuality in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20091215
Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells. Clinical and experimental pharmacology & physiology 20091201
Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice. Neurochemistry international 20091201
Clinical and pharmacogenetic determinants for the discontinuation of non-ergoline dopamine agonists in Parkinson's disease. European journal of clinical pharmacology 20091201
Dopamine agonists diminish value sensitivity of the orbitofrontal cortex: a trigger for pathological gambling in Parkinson's disease? Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20091201
Potential neuroprotection mechanisms in PD: focus on dopamine agonist pramipexole. Current medical research and opinion 20091201
Transdermal rotigotine: a clinically innovative dopamine-receptor agonist for the management of Parkinson's disease. Pharmacotherapy 20091201
Dopamine receptor agonists and sleep disturbances in Parkinson's disease. Parkinsonism & related disorders 20091201
Heterodimerization of dopamine receptors: new insights into functional and therapeutic significance. Parkinsonism & related disorders 20091201
Role of dopamine receptor agonists in the treatment of early Parkinson's disease. Parkinsonism & related disorders 20091201
Systematic review of the effect of dopamine receptor agonists on patient health-related quality of life. Parkinsonism & related disorders 20091201
Treatment of restless legs syndrome. Parkinsonism & related disorders 20091201
Dopamine receptor agonists and depression in Parkinson's disease. Parkinsonism & related disorders 20091201
Transdermal delivery of dopamine receptor agonists. Parkinsonism & related disorders 20091201
Reward networks in the brain as captured by connectivity measures. Frontiers in neuroscience 20091201
Serotonin-norepinephrine reuptake inhibitors for pain control: premise and promise. Current neuropharmacology 20091201
Biogenic amine depletion causes chronic muscular pain and tactile allodynia accompanied by depression: A putative animal model of fibromyalgia. Pain 20091101
Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study. Journal of neurochemistry 20091101
Oxidative neurodegeneration is prevented by UCP0045037, an allosteric modulator for the reduced form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. International journal of molecular sciences 20091101
Pharmacokinetics of a once-daily extended-release formulation of pramipexole in healthy male volunteers: three studies. Clinical therapeutics 20091101
An open-label conversion study of pramipexole to ropinirole prolonged release in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20091030
Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model. Experimental neurology 20091001
Critical review of ropinirole and pramipexole - putative dopamine D(3)-receptor selective agonists - for the treatment of RLS. Journal of clinical pharmacy and therapeutics 20091001
Fibromyalgia and myofascial pain syndrome-a dilemma. Indian journal of anaesthesia 20091001
Managing pathological gambling in Parkinson's disease with enteral levodopa/carbidopa infusions. Movement disorders : official journal of the Movement Disorder Society 20090915
Impulse control disorder behaviors associated with pramipexole used to treat fibromyalgia. Journal of gambling studies 20090901
Long-term retention rate of pramipexole in the treatment of Parkinson's disease. European journal of clinical pharmacology 20090901
Reward-learning and the novelty-seeking personality: a between- and within-subjects study of the effects of dopamine agonists on young Parkinson's patients. Brain : a journal of neurology 20090901
Pramipexole effects on startle gating in rats and normal men. Psychopharmacology 20090901
Dopamine agonists in 6-pyruvoyl tetrahydropterin synthase deficiency. Neurology 20090825
Antidepressant effects of pramipexole, a dopamine D3/D2 receptor agonist, and 7-OH-DPAT, a dopamine D3 receptor agonist, in olfactory bulbectomized rats. European journal of pharmacology 20090815
Disruption of nigrostriatal and cerebellothalamic pathways in dopamine responsive Holmes' tremor. Journal of neurology, neurosurgery, and psychiatry 20090801
Using prepulse inhibition to detect functional D3 receptor antagonism: effects of WC10 and WC44. Pharmacology, biochemistry, and behavior 20090801
REM sleep behavior disorder and narcolepsy. CNS & neurological disorders drug targets 20090801
Pathological gambling associated with cabergoline in a case of recurrent depression. Drug discoveries & therapeutics 20090801
Single dose of a dopamine agonist impairs reinforcement learning in humans: evidence from event-related potentials and computational modeling of striatal-cortical function. Human brain mapping 20090701
Effects of pramipexole on the duration of immobility during the forced swim test in normal and ACTH-treated rats. Naunyn-Schmiedeberg's archives of pharmacology 20090701
Association of the DRD2 and DRD3 polymorphisms with response to pramipexole in Parkinson's disease patients. European journal of clinical pharmacology 20090701
Homology modeling of adenosine A2A receptor and molecular docking for exploration of appropriate potent antagonists for treatment of Parkinson's disease. Current aging science 20090701
A dose-ranging study of pramipexole for the symptomatic treatment of restless legs syndrome: polysomnographic evaluation of periodic leg movements and sleep disturbance. Sleep medicine 20090601
Overnight switching from ergot-derived dopamine agonists to pramipexole in patients with Parkinson's disease: an open preliminary trial in Japan. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090601
The effect of antipsychotics on the high-affinity state of D2 and D3 receptors: a positron emission tomography study With [11C]-(+)-PHNO. Archives of general psychiatry 20090601
Trends in the molecular pathogenesis and clinical therapeutics of common neurodegenerative disorders. International journal of molecular sciences 20090601
Pramipexole induced compulsive behaviors abate after initiation of rotigitine. Movement disorders : official journal of the Movement Disorder Society 20090515
[Socioeconomic relevance of the idiopathic restless legs syndrome (RLS) in Germany: cost-of-illness study]. Medizinische Klinik (Munich, Germany : 1983) 20090515
Changes in artistic style and behaviour in Parkinson's disease: dopamine and creativity. Journal of neurology 20090501
Long-term effect of initiating pramipexole vs levodopa in early Parkinson disease. Archives of neurology 20090501
A case of compulsive behaviors observed in a restless legs syndrome patient treated with a dopamine agonist. Sleep 20090501
Treatment of sleep disorders after traumatic brain injury. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090415
Increased frequency and range of sexual behavior in a patient with Parkinson's disease after use of pramipexole: a case report. The journal of sexual medicine 20090401
The discriminative stimulus effects of dopamine D2- and D3-preferring agonists in rats. Psychopharmacology 20090401
Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice. The Journal of pharmacology and experimental therapeutics 20090401
Diagnosis and management of restless legs syndrome in children. Sleep medicine reviews 20090401
Frequency of new-onset pathologic compulsive gambling or hypersexuality after drug treatment of idiopathic Parkinson disease. Mayo Clinic proceedings 20090401
Effects of a dopamine receptor agonist and atropine sulfate on absorption of valproic acid in rats. Biomedical research (Tokyo, Japan) 20090401
Dopamine and cognitive functioning in de novo subjects with Parkinson's disease: effects of pramipexole and pergolide on working memory. Neuropsychologia 20090401
Mechanism and treatment of dropped head syndrome associated with parkinsonism. Parkinsonism & related disorders 20090301
Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy. Parkinsonism & related disorders 20090301
Antiparkinsonian drug-induced sleepiness: a double-blind placebo-controlled study of L-dopa, bromocriptine and pramipexole in healthy subjects. British journal of clinical pharmacology 20090301
Involvement of the subthalamic nucleus in engagement with behaviourally relevant stimuli. The European journal of neuroscience 20090301
Treatment options for restless legs syndrome. Expert opinion on pharmacotherapy 20090301
Reversible Pisa syndrome in patients with Parkinson's disease on dopaminergic therapy. Journal of neurology 20090301
Treatment of restless legs syndrome with iron infusion therapy. JAAPA : official journal of the American Academy of Physician Assistants 20090301
Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive element. International journal of molecular sciences 20090301
Targeting the progression of Parkinson's disease. Current neuropharmacology 20090301
Sustained administration of pramipexole modifies the spontaneous firing of dopamine, norepinephrine, and serotonin neurons in the rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201
Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of pramipexole in human plasma: application to a clinical pharmacokinetic study. Biomedical chromatography : BMC 20090201
High risk factors for valvular heart disease from dopamine agonists in patients with Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996) 20090201
Effective control of catatonia in Parkinson's disease by electroconvulsive therapy: a case report. European journal of neurology 20090201
[Impulse control disorder induced by the use of dopamine agonists]. Nederlands tijdschrift voor geneeskunde 20090117
Cardiac and noncardiac fibrotic reactions caused by ergot-and nonergot-derived dopamine agonists. Movement disorders : official journal of the Movement Disorder Society 20090115
[Pathological gambling induced by dopamine agonist]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20090110
Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans. Diabetes 20090101
The effect of pramipexole on mood and motivational symptoms in Parkinson's disease: a meta-analysis of placebo-controlled studies. Clinical therapeutics 20090101
[The role of low-dose pramipexole in the treatment of treatment-resistant bipolar depression: a case report]. Turk psikiyatri dergisi = Turkish journal of psychiatry 20090101
Muscle modifications in fibromyalgic patients revealed by surface electromyography (SEMG) analysis. BMC musculoskeletal disorders 20090101
Fibromyalgia: diagnosis and treatment options. Gender medicine 20090101
A review of ropinirole prolonged release in Parkinson's disease. Clinical interventions in aging 20090101
Dopamine Agonists and their risk to induce psychotic episodes in Parkinson's disease: a case-control study. BMC neurology 20090101
Update on ropinirole in the treatment of Parkinson's disease. Neuropsychiatric disease and treatment 20090101
Restless legs syndrome: differential diagnosis and management with rotigotine. Neuropsychiatric disease and treatment 20090101
Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease. BMC neuroscience 20090101
Cost effectiveness of rasagiline and pramipexole as treatment strategies in early Parkinson's disease in the UK setting: an economic Markov model evaluation. Drugs & aging 20090101
[Influence of dopamine agonist pramipexole (mirapex) on tremor, cognitive and affective impairment in patients with Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
Restless legs syndrome: differential diagnosis and management with pramipexole. Clinical interventions in aging 20090101
[Fatigability in Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
Levodopa/carbidopa/entacapone 200/50/200 mg (Stalevo 200) in the treatment of Parkinson's disease: a case series. Cases journal 20090101
Visual hallucinations associated with varenicline: a case report. Journal of medical case reports 20090101
Sleep disorders in Parkinson's disease. Neuropsychiatric disease and treatment 20090101
Current and emerging treatments for amyotrophic lateral sclerosis. Neuropsychiatric disease and treatment 20090101
Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury. Oxidative medicine and cellular longevity 20090101
An unusual case of spontaneous multi vessel coronary artery dissection in an elderly patient: a case report. Cases journal 20090101
[Restless leg syndrome: diagnosis and treatment]. Glas. Srpska akademija nauka i umetnosti. Odeljenje medicinskih nauka 20090101
Impulse control disorders in Parkinson's disease. F1000 medicine reports 20090101
Hallucinations: Etiology and clinical implications. Industrial psychiatry journal 20090101
Pramipexole as a possible cause of the syndrome of inappropriate antidiuresis. BMJ case reports 20090101
Treatment of restless legs syndrome: an evidence-based review and implications for clinical practice. Movement disorders : official journal of the Movement Disorder Society 20081215
Adenosine A(2A) receptors in Parkinson's disease treatment. Purinergic signalling 20081201
Cabergoline and pramipexole fail to modify already established dyskinesias in an animal model of parkinsonism. Behavioural brain research 20081201
Effect of pramipexole on RLS symptoms and sleep: a randomized, double-blind, placebo-controlled trial. Sleep medicine 20081201
Pragmatic consideration of recent randomized, placebo-controlled clinical trials for treatment of fibromyalgia. Current pain and headache reports 20081201
Heritable strain differences in sensitivity to the startle gating-disruptive effects of D2 but not D3 receptor stimulation. Behavioural pharmacology 20081201
Toward achieving optimal response: understanding and managing antidepressant side effects. Dialogues in clinical neuroscience 20081201
Treatment options and patient perspectives in the management of fibromyalgia: future trends. Neuropsychiatric disease and treatment 20081201
New treatment options in the management of fibromyalgia: role of pregabalin. Neuropsychiatric disease and treatment 20081201
Dopamine agonist-based strategies in the treatment of Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20081201
Pharmacology and therapeutic potential of sigma(1) receptor ligands. Current neuropharmacology 20081201
Neurophysiology of sleep and wakefulness: basic science and clinical implications. Current neuropharmacology 20081201
Bromocriptine, a dopamine D(2) receptor agonist with the structure of the amino acid ergot alkaloids, induces neurite outgrowth in PC12 cells. European journal of pharmacology 20081119
Hiccups and dopamine. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081115
[D3 agonism: an augmentative treatment in tardive dyskinesia? A case report]. Psychiatrische Praxis 20081101
Late onset dopa-responsive dystonia with tremor, gait freezing and behavioural disturbance and a normal dopamine transporter scan. Age and ageing 20081101
[Restless-leg syndrome--possible unrecognized cause for insomnia and irritability in children]. No to hattatsu = Brain and development 20081101
Design, synthesis, and evaluation of potent and selective ligands for the dopamine 3 (D3) receptor with a novel in vivo behavioral profile. Journal of medicinal chemistry 20081009
Meta-analysis of the efficacy and tolerability of pramipexole versus ropinirole in the treatment of restless legs syndrome. Sleep medicine 20081001
Discontinuation of ropinirole and pramipexole in patients with Parkinson's disease: clinical practice versus clinical trials. European journal of clinical pharmacology 20081001
Heart valve abnormalities in Parkinson's disease treated with dopamine agonists. Journal of neurology 20081001
Cost-effectiveness of licensed treatment options for restless legs syndrome in the UK and Sweden. Current medical research and opinion 20081001
Lack of effects of pramipexole on REM sleep behavior disorder in Parkinson disease. Sleep 20081001
Analysis of the anti-Parkinson drug pramipexole in human urine by capillary electrophoresis with laser-induced fluorescence detection. Analytica chimica acta 20080919
Interactions between antiparkinsonian drugs and ABCB1/P-glycoprotein at the blood-brain barrier in a rat brain endothelial cell model. Neuroscience letters 20080905
Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain structure & function 20080901
Sleep dysfunction in heart failure. Current treatment options in neurology 20080901
Defining the boundaries of the response of sleep leg movements to a single dose of dopamine agonist. Sleep 20080901
Unraveling depression in Parkinson's disease. European journal of neurology 20080901
Dopaminergic modulation of semantic priming in Parkinson disease. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20080901
[Pathological gambling and Parkinson disease]. Brain and nerve = Shinkei kenkyu no shinpo 20080901
[Case of a 30-year history of PARK6 --findings from functional imaging of the brain]. Rinsho shinkeigaku = Clinical neurology 20080901
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part I: principles of functional organisation. Current neuropharmacology 20080901
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans. Current neuropharmacology 20080901
Pramipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity. Neuroscience letters 20080801
Continuous subcutaneous infusion of pramipexole protects against lipopolysaccharide-induced dopaminergic cell death without affecting the inflammatory response. Experimental neurology 20080801
Parkinson's disease and dopaminergic therapy--differential effects on movement, reward and cognition. Brain : a journal of neurology 20080801
Beneficial effect of pramipexole for motor function and depression in Parkinson's disease. Neuropsychiatric disease and treatment 20080801
Current approaches to the treatment of Parkinson's disease. Neuropsychiatric disease and treatment 20080801
Psychiatric disorders and traumatic brain injury. Neuropsychiatric disease and treatment 20080801
Synthesis and pharmacological investigation of novel 2-aminothiazole-privileged aporphines. Bioorganic & medicinal chemistry 20080715
Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA. Journal of neural transmission (Vienna, Austria : 1996) 20080701
Open-label study of the long-term efficacy and safety of pramipexole in patients with Restless Legs Syndrome (extension of the PRELUDE study). Sleep medicine 20080701
Valproate-induced parkinsonism, glial cells and Alexander's disease. Progress in neuro-psychopharmacology & biological psychiatry 20080701
[Two cases of patients with Parkinson's disease developing valvular heart disease while taking cabergoline]. Rinsho shinkeigaku = Clinical neurology 20080701
Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling. Neuropharmacology 20080601
Internal medicine: guidance to the diagnosis and management of restless legs syndrome. Southern medical journal 20080601
Restless legs syndrome in women: a review. Journal of women's health (2002) 20080601
A 77-year-old man with Parkinson's disease and hyperthermia. Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20080601
Medications for restless legs syndrome in pregnancy. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20080601
Fatal intoxication using amantadine and pramipexole in a uremic patient. Acta neurologica Taiwanica 20080601
Treatment of fragile X-associated tremor ataxia syndrome (FXTAS) and related neurological problems. Clinical interventions in aging 20080601
The frequency of cardiac valvular regurgitation in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20080515
Food restriction alters N'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine dihydrochloride (pramipexole)-induced yawning, hypothermia, and locomotor activity in rats: evidence for sensitization of dopamine D2 receptor-mediated effects. The Journal of pharmacology and experimental therapeutics 20080501
Rotigotine transdermal system for the treatment of Parkinson's disease. Clinical therapeutics 20080501
Medications used to treat Parkinson's disease and the risk of gambling. European journal of neurology 20080401
Depressive symptoms in Parkinson's disease. European journal of neurology 20080401
Protection against Parkinson's disease progression: clinical experience. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20080401
Pramipexole-induced psychosis in Parkinson's disease. Psychiatry and clinical neurosciences 20080401
Dopamine agonists in Parkinson's disease. Expert review of neurotherapeutics 20080401
Rotigotine: Parkinson's disease: a step backward. Prescrire international 20080401
Update on the use of pramipexole in the treatment of Parkinson's disease. Neuropsychiatric disease and treatment 20080401
Regulation of intracellular dopamine levels by dopaminergic drugs: involvement of vesicular monoamine transporter. European journal of pharmacology 20080317
Dopaminergic drug-induced tics in PARK2-positive Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20080315
A novel synthesis and pharmacological evaluation of a potential dopamine D1/D2 agonist: 1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol. Bioorganic & medicinal chemistry 20080315
Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria? Genes, brain, and behavior 20080301
Interaction between levodopa and enteral nutrition. The Annals of pharmacotherapy 20080301
[Isolated pulmonary hypertension and pergolide]. Revue neurologique 20080301
Restless arms. Lancet (London, England) 20080209
Single dose of a dopamine agonist impairs reinforcement learning in humans: behavioral evidence from a laboratory-based measure of reward responsiveness. Psychopharmacology 20080201
[Fibromyalgia syndrome: new developments in pharmacotherapy]. Zeitschrift fur Rheumatologie 20080201
Restless legs syndrome in older adults. Clinics in geriatric medicine 20080201
Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers. Journal of clinical psychopharmacology 20080201
Burning mouth syndrome responsive to pramipexol. The journal of headache and pain 20080201
Clinical experience with pramipexole in the treatment of restless legs syndrome. Expert opinion on drug metabolism & toxicology 20080201
R+ pramipexole as a mitochondrially focused neuroprotectant: initial early phase studies in ALS. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20080201
Patterns of treatment for restless legs syndrome in primary care in the United Kingdom. Clinical therapeutics 20080201
Depression in Parkinson's disease: health risks, etiology, and treatment options. Neuropsychiatric disease and treatment 20080201
Optimizing levodopa therapy for Parkinson's disease with levodopa/carbidopa/entacapone: implications from a clinical and patient perspective. Neuropsychiatric disease and treatment 20080201
Paradoxical aspects of parkinsonian tremor. Movement disorders : official journal of the Movement Disorder Society 20080130
Pramipexole-induced antecollis in Parkinson's disease. Journal of the neurological sciences 20080115
[Pramipexole and Parkinson's disease, an update]. Revista de neurologia 20080101
Pramipexole safely replaces ergot dopamine agonists with either rapid or slow switching. The Journal of international medical research 20080101
Spotlight on rotigotine in Parkinson's disease. Drugs & aging 20080101
Conversion from dopamine agonists to cabergoline: an open-label trial in 128 patients with advanced Parkinson disease. Clinical neuropharmacology 20080101
Antiparkinsonian medication and pathological gambling. CNS drugs 20080101
Development and evaluation of push-pull based osmotic delivery system for pramipexole. PDA journal of pharmaceutical science and technology 20080101
Impact of newer pharmacological treatments on quality of life in patients with Parkinson's disease. CNS drugs 20080101
Dopamine agonist increases risk taking but blunts reward-related brain activity. PloS one 20080101
[Mirapex (pramipexole) in the treatment of non-motor disturbances in Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
Haptic perception of object curvature in Parkinson's disease. PloS one 20080101
A meta-analysis of the efficacy of fibromyalgia treatment according to level of care. Arthritis research & therapy 20080101
[Restless-legs syndrome]. Revue neurologique 20080101
Cost effectiveness of pharmacotherapies in early Parkinson's disease. CNS drugs 20080101
KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis. CNS neuroscience & therapeutics 20080101
HIV, visceral leishmaniasis and Parkinsonism combined with diabetes mellitus and hyperuricaemia: A case report. Cases journal 20080101
[Pain and depression in Parkinson's disease: new therapeutic possibilities of pramipexole]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
Pramipexole-induced dropped head syndrome in Parkinson's disease. Internal medicine (Tokyo, Japan) 20080101
Pathological hypersexuality induced by dopamine replacement therapy in a patient with progressive supranuclear palsy. The Journal of neuropsychiatry and clinical neurosciences 20080101
The treatment of Parkinson's disease with dopamine agonists. GMS health technology assessment 20080101
Design and synthesis of a functionally selective D3 agonist and its in vivo delivery via the intranasal route. Bioorganic & medicinal chemistry letters 20071215
Antiparkinson therapeutic potencies correlate with their affinities at dopamine D2(High) receptors. Synapse (New York, N.Y.) 20071201
Reversible dopamine agonist induced anterocollis in a multiple system atrophy patient. Movement disorders : official journal of the Movement Disorder Society 20071115
Comparison of pramipexole with and without domperidone co-administration on alertness, autonomic, and endocrine functions in healthy volunteers. British journal of clinical pharmacology 20071101
Quantification of pramipexole in human plasma by liquid chromatography tandem mass spectrometry using tamsulosin as internal standard. Biomedical chromatography : BMC 20071101
Rapid eye movement sleep behavior disorder. The Annals of pharmacotherapy 20071101
Clinical practice regarding dopamine-agonist use and driving in Parkinson's disease. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20071101
[Sleep disorder as alarm symptom]. MMW Fortschritte der Medizin 20071025
Dopaminergic agonists: possible neurorescue drugs endowed with independent and synergistic multisites of action. Neurochemical research 20071001
Restless legs syndrome: nonpharmacologic and pharmacologic treatments. Geriatrics 20071001
Fibrotic heart-valve reactions to dopamine-agonist treatment in Parkinson's disease. The Lancet. Neurology 20070901
Restless legs syndrome and periodic limb movements during sleep: diagnosis and treatment. The neurologist 20070901
MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine. Purinergic signalling 20070901
Pramipexole and compulsive masturbation. Psychiatry (Edgmont (Pa. : Township)) 20070901
Pramipexole prevents neurotoxicity induced by oligomers of beta-amyloid. European journal of pharmacology 20070827
Using STN DBS and medication reduction as a strategy to treat pathological gambling in Parkinson's disease. Parkinsonism & related disorders 20070801
Yawning and hypothermia in rats: effects of dopamine D3 and D2 agonists and antagonists. Psychopharmacology 20070801
First night efficacy of pramipexole in restless legs syndrome and periodic leg movements. Sleep medicine 20070801
Pramipexole in psychiatry: a systematic review of the literature. The Journal of clinical psychiatry 20070801
Impact of pramipexole on the onset of levodopa-related dyskinesias. Movement disorders : official journal of the Movement Disorder Society 20070715
Risk factors for somnolence, edema, and hallucinations in early Parkinson disease. Neurology 20070710
Dopamine agonists and cardiac valvulopathy in Parkinson disease: a case-control study. Neurology 20070703
Efficacy and safety of pramipexole in restless legs syndrome. Current neurology and neuroscience reports 20070701
Use of the dopamine receptor agonist Mirapex in the treatment of Parkinson's disease. Neuroscience and behavioral physiology 20070701
Orthostatic tremor in progressive supranuclear palsy. Movement disorders : official journal of the Movement Disorder Society 20070615
Risk factors for the development of pedal edema in patients using pramipexole. Archives of neurology 20070601
Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: a double-blind, double-dummy, randomised controlled trial. The Lancet. Neurology 20070601
Rasagiline - a novel MAO B inhibitor in Parkinson's disease therapy. Therapeutics and clinical risk management 20070601
Continuous levodopa for advanced Parkinson's disease. Neuropsychiatric disease and treatment 20070601
Efficacy and safety of pramipexole in restless legs syndrome. Neurology 20070508
Sleep and aging: 2. Management of sleep disorders in older people. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070508
Panic attack like episodes possibly associated with pramipexole therapy in Parkinson's disease. European journal of neurology 20070501
Belly dancer's syndrome following central pontine and extrapontine myelinolysis. Movement disorders : official journal of the Movement Disorder Society 20070430
Blood-brain barrier transport of pramipexole, a dopamine D2 agonist. Life sciences 20070403
Responsiveness to a dopamine agent in Holmes tremor--case report. European journal of neurology 20070401
The effects of L-3,4-dihydroxyphenylalanine and dopamine agonists on dopamine neurons in the progressive hemiparkinsonian rat models. Neurological research 20070401
Pramipexole (Mirapex) for restless legs syndrome. The Medical letter on drugs and therapeutics 20070326
Cardiac valve regurgitation with pergolide compared with nonergot agonists in Parkinson disease. Archives of neurology 20070301
Treatment of juvenile Parkinson disease and the recurrent emergence of pathologic gambling. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20070301
Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity. European journal of pharmacology 20070227
Dopamine D3 receptor agonists for protection and repair in Parkinson's disease. Current opinion in pharmacology 20070201
A case of mania following the use of pramipexole. The American journal of psychiatry 20070201
Pramipexole: new indication. Restless legs: still no satisfactory drug treatment. Prescrire international 20070201
Pathological gambling and dopamine agonists: A phenotype? Neuropsychiatric disease and treatment 20070201
Impaired cognition and attention in adults: pharmacological management strategies. Neuropsychiatric disease and treatment 20070201
The four As associated with pathological Parkinson disease gamblers: anxiety, anger, age, and agonists. Neuropsychiatric disease and treatment 20070201
[Pramipexole therapy of restless legs syndrome]. Ideggyogyaszati szemle 20070120
Valvular heart disease in Parkinson's disease patients treated with dopamine agonists: a reader-blinded monocenter echocardiography study. Movement disorders : official journal of the Movement Disorder Society 20070115
Efficacy of pramipexole in restless legs syndrome: a six-week, multicenter, randomized, double-blind study (effect-RLS study). Movement disorders : official journal of the Movement Disorder Society 20070115
Restless arm symptoms as an extension of restless leg syndrome. Age and ageing 20070101
Bipolar depression: a review of randomised clinical trials. Expert opinion on pharmacotherapy 20070101
[Antidepressant effects of dopamine agonists. Experimental and clinical findings]. Der Nervenarzt 20070101
Drug adverse events and drop-out risk: a clinical case. Archives of gerontology and geriatrics 20070101
Pramipexole in levodopa-treated Parkinson disease patients of African, Asian, and Hispanic heritage. Clinical neuropharmacology 20070101
Pramipexole: in restless legs syndrome. CNS drugs 20070101
The implications of using US-specific EQ-5D preference weights for cost-effectiveness evaluation. Medical decision making : an international journal of the Society for Medical Decision Making 20070101
State of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndrome. Movement disorders : official journal of the Movement Disorder Society 20070101
Biology and therapy of fibromyalgia. Stress, the stress response system, and fibromyalgia. Arthritis research & therapy 20070101
Medical management of levodopa-associated motor complications in patients with Parkinson's disease. CNS drugs 20070101
High prevalence of extrapyramidal signs and symptoms in a group of Italian dental technicians. BMC neurology 20070101
Gambling and increased sexual desire with dopaminergic medications in restless legs syndrome. Clinical neuropharmacology 20070101
Overnight switch from oral dopaminergic agonists to transdermal rotigotine patch in subjects with Parkinson disease. Clinical neuropharmacology 20070101
The effect of levodopa and dopamine agonists on optic nerve head in Parkinson disease. European journal of ophthalmology 20070101
[Neuroprotective effect of dopamine agonists]. Neurologia i neurochirurgia polska 20070101
[Dopamine agonists in the treatment of motor complications in advanced Parkinson's disease]. Neurologia i neurochirurgia polska 20070101
Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease. CNS drugs 20070101
Cerebral and Extracranial Neurodegeneration are Strongly Coupled in Parkinson's Disease. The open neurology journal 20070101
In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates, the selective 5-hydroxytryptamine 1a agonist (R)-(+)-8-OHDPAT inhibits levodopa-induced dyskinesia but only with\ increased motor disability. The Journal of pharmacology and experimental therapeutics 20061201
Long-term treatment with pramipexole in restless legs syndrome. European journal of neurology 20061201
Neuroprotection in Parkinson models varies with toxin administration protocol. The European journal of neuroscience 20061201
Epilepsy, parkinsonism, and neuroleptic malignant syndrome in a child. Journal of child neurology 20061201
Factors associated with the development of motor fluctuations and dyskinesias in Parkinson disease. Archives of neurology 20061201
End-of-dose deterioration in non ergolinic dopamine agonist monotherapy of Parkinson's disease. Journal of neurology 20061201
Restless leg syndrome: is it a real problem? Therapeutics and clinical risk management 20061201
Restless legs is a medical disorder and can be treated. Neuropsychiatric disease and treatment 20061201
Pramipexole: new use for an old drug - the potential use of pramipexole in the treatment of restless legs syndrome. Neuropsychiatric disease and treatment 20061201
Ropinirole for the treatment of restless legs syndrome. Neuropsychiatric disease and treatment 20061201
Rotigotine transdermal system: a short review. Neuropsychiatric disease and treatment 20061201
The biopsychosocial effects of restless legs syndrome (RLS). Neuropsychiatric disease and treatment 20061201
Effects of restless legs syndrome (RLS) on sleep. Neuropsychiatric disease and treatment 20061201
Comparison of pramipexole and modafinil on arousal, autonomic, and endocrine functions in healthy volunteers. Journal of psychopharmacology (Oxford, England) 20061101
Increase in body weight after pramipexole treatment in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20061101
Telogen effluvium associated with the dopamine agonist pramipexole in a 55-year-old woman with Parkinson's disease. Journal of the American Academy of Dermatology 20061101
A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease. Journal of the neurological sciences 20061025
Effects of the dopamine agonist pramipexole on depression, anhedonia and motor functioning in Parkinson's disease. Journal of the neurological sciences 20061025
Dopamine agonists and cardiac valvulopathy in Parkinson disease: a case-control study. Neurology 20061010
The weight of evidence for ropinirole in restless legs syndrome. European journal of neurology 20061001
Dopamine agonist therapy in low-response children following traumatic brain injury. Journal of child neurology 20061001
Efficacy and safety of pramipexole in restless legs syndrome. Neurology 20060926
Controlled withdrawal of pramipexole after 6 months of open-label treatment in patients with restless legs syndrome. Movement disorders : official journal of the Movement Disorder Society 20060901
Comparison of pramipexole and amisulpride on alertness, autonomic and endocrine functions in healthy volunteers. Psychopharmacology 20060901
New-onset narcolepsy with cataplexy in a geriatric patient. Sleep medicine 20060901
[Pathological gambling associated with pramipexole use in Parkinson's disease]. Revista de neurologia 20060901
[Treatment of Parkinson disease: therapeutic reserve of the dopaminergic agonist]. Neurologia (Barcelona, Spain) 20060901
Surrogate outcomes in neurology, psychiatry, and psychopharmacology. Dialogues in clinical neuroscience 20060901
Patterns of prefrontal dysfunction in alcoholics with and without Korsakoff's syndrome, patients with Parkinson's disease, and patients with rupture and repair of the anterior communicating artery. Neuropsychiatric disease and treatment 20060901
Religiosity in patients with Parkinson's disease. Neuropsychiatric disease and treatment 20060901
Valvular heart disease in Parkinson's disease vs. controls: An echocardiographic study. Movement disorders : official journal of the Movement Disorder Society 20060801
Efficacy and safety of pramipexole in idiopathic restless legs syndrome: a polysomnographic dose-finding study--the PRELUDE study. Sleep medicine 20060801
Use of pramipexole in REM sleep behavior disorder: results from a case series. Sleep medicine 20060801
[Reversible pathological gambling under treatment with pramipexole]. Der Nervenarzt 20060801
[Dopamine agonists for treatment of restless leg syndrome]. Medizinische Monatsschrift fur Pharmazeuten 20060801
Ergoline and non-ergoline derivatives in the treatment of Parkinson's disease. Journal of neurology 20060801
A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. Clinical therapeutics 20060801
[A case of Parkinson's disease with neuroleptic malignant syndrome induced by paroxetine]. Rinsho shinkeigaku = Clinical neurology 20060801
Association of dopamine agonist use with impulse control disorders in Parkinson disease. Archives of neurology 20060701
Validated chiral liquid chromatographic method for the enantiomeric separation of Pramipexole dihydrochloride monohydrate. Journal of pharmaceutical and biomedical analysis 20060616
[More on therapeutic options in fibromyalgia]. Medicina clinica 20060610
[Restless legs syndrome: when uncontrollable urge to move afflicts the patient...]. MMW Fortschritte der Medizin 20060608
Chronic cluster headache responsive to pramipexole. Cephalalgia : an international journal of headache 20060601
[Pre-launching of drugs--the RLS example]. Lakartidningen 20060601
Future prospects in depression research. Dialogues in clinical neuroscience 20060601
Treatments in depression. Dialogues in clinical neuroscience 20060601
[Case of juvenile parkinsonism in pregnancy]. Rinsho shinkeigaku = Clinical neurology 20060601
Restless legs syndrome: diagnosis and review of management options. Neuropsychiatric disease and treatment 20060601
Pramipexole versus sertraline in the treatment of depression in Parkinson's disease: a national multicenter parallel-group randomized study. Journal of neurology 20060501
Practice Parameter: treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 20060411
Compulsive eating and weight gain related to dopamine agonist use. Movement disorders : official journal of the Movement Disorder Society 20060401
Hiccups associated with dopamine agonists in Parkinson disease. Neurology 20060314
Patch clamp reveals powerful blockade of the mitochondrial permeability transition pore by the D2-receptor agonist pramipexole. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Pramipexole protects against MPTP toxicity in non-human primates. Journal of neurochemistry 20060301
Pramipexole for the treatment of restless legs syndrome. Expert opinion on pharmacotherapy 20060301
Restless legs syndrome: facts & treatments. This strange malady affects 12 million Americans, many of whom go misdiagnosed or undiagnosed. Health news (Waltham, Mass.) 20060301
Pramipexole: augmentation in the treatment of depressive symptoms. CNS spectrums 20060301
Pisa syndrome without neuroleptic exposure in a patient with Parkinson's disease: case report. Movement disorders : official journal of the Movement Disorder Society 20060201
Gambling and Parkinson disease. Archives of neurology 20060201
Targeted antioxidative and neuroprotective properties of the dopamine agonist pramipexole and its nondopaminergic enantiomer SND919CL2x [(+)2-amino-4,5,6,7-tetrahydro-6-Lpropylamino-benzathiazole dihydrochloride]. The Journal of pharmacology and experimental therapeutics 20060101
The neurophysiology of the alternating leg muscle activation (ALMA) during sleep: study of one patient before and after treatment with pramipexole. Sleep medicine 20060101
Pramipexole protects against H2O2-induced PC12 cell death. Naunyn-Schmiedeberg's archives of pharmacology 20060101
Motor deficits in Parkinsonian reaching: dopa-sensitivity influenced by real-world task constraint. Journal of motor behavior 20060101
Pramipexole versus levodopa in patients with early Parkinson's disease: effect on generic and disease-specific quality of life. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20060101
Pharmacokinetic optimisation in the treatment of Parkinson's disease : an update. Clinical pharmacokinetics 20060101
Proposed dose equivalence for rapid switch between dopamine receptor agonists in Parkinson's disease: a review of the literature. Clinical therapeutics 20060101
Management of restless legs syndrome in patients on dialysis. Drugs 20060101
Review of evidence that posttransplantation psychiatric treatment commonly affects prolactin levels and thereby influences graft fate. General hospital psychiatry 20060101
Reversal learning in Parkinson's disease depends on medication status and outcome valence. Neuropsychologia 20060101
Biology and therapy of fibromyalgia. New therapies in fibromyalgia. Arthritis research & therapy 20060101
[Dopamine receptors agonists (mirapex) in the treatment of Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
Pharmacological management of Huntington's disease: an evidence-based review. Current pharmaceutical design 20060101
Duloxetine compared with fluoxetine and venlafaxine: use of meta-regression analysis for indirect comparisons. BMC psychiatry 20060101
Biology and therapy of fibromyalgia. Genetic aspects of fibromyalgia syndrome. Arthritis research & therapy 20060101
Phenomenology and management of cognitive and behavioral disorders in Parkinson's disease. Rise and logic of dementia in Parkinson's disease. Annals of general psychiatry 20060101
Mechanism of synergistic action following co-treatment with pramipexole and fluoxetine or sertraline in the forced swimming test in rats. Pharmacological reports : PR 20060101
Using pramipexole in neuropsychiatry: a cautionary note. The Journal of neuropsychiatry and clinical neurosciences 20060101
[7-year experience in usage of mirapex in patients with different forms of primary parkinsonism]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
A comparative study on the cost of new antibiotics and drugs of other therapeutic categories. PloS one 20060101
The acute effect of a low dosage of pramipexole on severe idiopathic restless legs syndrome: an open-label trial. Neuropsychobiology 20060101
Optimization of chiral separation of pramipexole on various polisaccharide stationary phases. Acta poloniae pharmaceutica 20060101
Changing dopamine agonist treatment in Parkinson's disease: experiences with switching to pramipexole. Journal of neural transmission. Supplementum 20060101
Restless Legs Syndrome: The underrecognised condition. The Libyan journal of medicine 20060101
Parkinson's drug may relieve fibromyalgia pain. Health news (Waltham, Mass.) 20051201
Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment. Psychopharmacology 20051101
Antiparkinson concentrations of pramipexole and PHNO occupy dopamine D2(high) and D3(high) receptors. Synapse (New York, N.Y.) 20051101
Present and future drug treatment for Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry 20051101
Dopamine D3 receptor-preferring agonists induce neurotrophic effects on mesencephalic dopamine neurons. The European journal of neuroscience 20051101
Treatment of fibromyalgia: a changing of the guard. Women's health (London, England) 20051101
[The role of dopaminagonists in the treatment of Parkinson's disease]. Praxis 20051019
Pathological gambling in Parkinson's disease. The Lancet. Neurology 20051001
Neuroprotective therapy in Parkinson's disease: current status and new directions from experimental and genetic clues. Journal of clinical neurology (Seoul, Korea) 20051001
Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists. Journal of medicinal chemistry 20050908
Pathological gambling caused by drugs used to treat Parkinson disease. Archives of neurology 20050901
Pathological hypersexuality predominantly linked to adjuvant dopamine agonist therapy in Parkinson's disease and multiple system atrophy. Parkinsonism & related disorders 20050901
Pramipexole in the treatment of Parkinson's disease: new developments. Expert review of neurotherapeutics 20050901
A randomized, double-blind, placebo-controlled trial of pramipexole, a dopamine agonist, in patients with fibromyalgia receiving concomitant medications. Arthritis and rheumatism 20050801
Sudden uncontrollable somnolence and medication use in Parkinson disease. Archives of neurology 20050801
Pleuropulmonary fibrosis after long-term treatment with the dopamine agonist pergolide for Parkinson Disease. Archives of neurology 20050801
REM sleep behaviour disorder: clinical profiles and pathophysiology. International review of psychiatry (Abingdon, England) 20050801
Pramipexole has ameliorating effects on levodopa-induced abnormal dopamine turnover in parkinsonian striatum and quenching effects on dopamine-semiquinone generated in vitro. Neurological research 20050701
A pilot double-blind placebo-controlled trial of low-dose pramipexole in sleep-related eating disorder. European journal of neurology 20050601
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Long-term efficacy and safety of pramipexole in advanced Parkinson's disease: results from a European multicenter trial. Movement disorders : official journal of the Movement Disorder Society 20050501
Actometry in measuring the symptom severity of restless legs syndrome. European journal of neurology 20050501
Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004. Movement disorders : official journal of the Movement Disorder Society 20050501
CoMFA and CoMSIA investigations revealing novel insights into the binding modes of dopamine D3 receptor agonists. Journal of medicinal chemistry 20050407
Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney. Drug metabolism and disposition: the biological fate of chemicals 20050401
D3 dopamine receptors do not regulate neurogenesis in the subventricular zone of adult mice. Neurobiology of disease 20050401
Pramipexole, ropinirole, and mania in Parkinson's disease. The American journal of psychiatry 20050401
Biological effects of pramipexole on dopaminergic neuron-associated genes: relevance to neuroprotection. Neuroscience letters 20050329
'Levodopa phobia': a new iatrogenic cause of disability in Parkinson disease. Neurology 20050308
Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence. Addiction (Abingdon, England) 20050301
Sleep attacks in patients receiving dopamine-receptor agonists. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050301
Recovery from parkinson syndrome and prolonged visually evoked potentials in hepatic encephalopathy. Metabolic brain disease 20050301
Mild cognitive impairment in Parkinson's disease: the challenge and the promise. Neuropsychiatric disease and treatment 20050301
Molecular studies probe bipolar disorder. JAMA 20050202
Pergolide effect on cognitive functions in early-mild Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996) 20050201
Sleep episodes and daytime somnolence as result of individual susceptibility to different dopaminergic drugs in a PD patient: a polysomnographic study. Journal of the neurological sciences 20050115
A randomly assigned double-blind cross-over study examining the relative anti-parkinsonian tremor effects of pramipexole and pergolide. European journal of neurology 20050101
Cognitive performance in people with Parkinson's disease and mild or moderate depression: effects of dopamine agonists in an add-on to L-dopa therapy. European journal of neurology 20050101
Diagnosis and management of patients with bipolar II disorder. The Journal of clinical psychiatry 20050101
[Organ changes induced by ergot derivative dopamine agonist drugs: time to change treatment guidelines in Parkinson's disease?]. Casopis lekaru ceskych 20050101
Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexole. The Journal of neuropsychiatry and clinical neurosciences 20050101
[Syndrome of inappropriate ADH secretion (SIADH) induced by pramipexole in a patient with Parkinson's disease]. Nihon Jinzo Gakkai shi 20050101
Newer treatment studies for bipolar depression. Bipolar disorders 20050101
Fluoxetine versus other types of pharmacotherapy for depression. The Cochrane database of systematic reviews 20050101
Pramipexole and levodopa in early Parkinson's disease: dynamic changes in cost effectiveness. PharmacoEconomics 20050101
Short review on dopamine agonists: insight into clinical and research studies relevant to Parkinson's disease. Pharmacological reports : PR 20050101
Pramipexole in restless legs syndrome: an evidence-based review of its effectiveness on clinical outcomes. Core evidence 20050101
Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms. Journal of neurochemistry 20041201
[Pramipexole for intractable hiccups]. Medicina clinica 20041113
Switching from ergot to nonergot dopamine agonists in Parkinson's disease: a clinical series and five-drug dose conversion table. Movement disorders : official journal of the Movement Disorder Society 20041101
Predictors of sudden onset of sleep in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20041101
Involvement of dopamine D(2)/D(3) receptors and BDNF in the neuroprotective effects of S32504 and pramipexole against 1-methyl-4-phenylpyridinium in terminally differentiated SH-SY5Y cells. Experimental neurology 20041101
Periodic leg movements in prepubertal children with sleep disturbance. Developmental medicine and child neurology 20041101
[Diseases other than Parkinson's disease presenting with parkinsonism]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20041101
Effect of monoamine reuptake inhibitor NS 2330 in advanced Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20041001
The activity of pramipexole in the mouse forced swim test is mediated by D2 rather than D3 receptors. Psychopharmacology 20040901
SL25.1131 [3(S),3a(S)-3-methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a new, reversible, and mixed inhibitor of monoamine oxidase-A and monoamine oxidase-B: biochemical and behavioral profile. The Journal of pharmacology and experimental therapeutics 20040901
Pramipexole-treated Parkinson's disease during pregnancy. Movement disorders : official journal of the Movement Disorder Society 20040901
[Treatment for patients with early Parkinson's disease]. Nihon rinsho. Japanese journal of clinical medicine 20040901
Depression and Parkinson's disease. Journal of neurology 20040901
Drug treatment of Parkinson's disease. Dialogues in clinical neuroscience 20040901
Imaging dopamine neurotransmission in Parkinson's disease: biomarker versus surrogate end point. Dialogues in clinical neuroscience 20040901
The effects of dopamine D3 agonists and antagonists in a nonhuman primate model of tardive dyskinesia. Pharmacology, biochemistry, and behavior 20040801
Calming restless legs. Sleep 20040801
Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biological psychiatry 20040701
Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial. Archives of neurology 20040701
[Pharmacological profiles and clinical effects of antiparkinsonian agent, pramipexole]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040601
Practice parameters for the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. Sleep 20040501
An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. Sleep 20040501
Pramipexole for the treatment of uremic restless legs in patients undergoing hemodialysis. Neurology 20040309
Preliminary randomized, double-blind, placebo-controlled trial of pramipexole added to mood stabilizers for treatment-resistant bipolar depression. The American journal of psychiatry 20040301
Conversion from dopamine agonists to pramipexole. An open-label trial in 227 patients with advanced Parkinson's disease. Journal of neurology 20040301
Current perspectives in the management of treatment-resistant depression. Dialogues in clinical neuroscience 20040301
Modulation of ATP levels alters the mode of hydrogen peroxide-induced cell death in primary cortical cultures: effects of putative neuroprotective agents. Brain research 20040130
Slowing Parkinson's disease progression: recent dopamine agonist trials. Neurology 20040127
Slowing Parkinson's disease progression: recent dopamine agonist trials. Neurology 20040127
Augmentation and tolerance with long-term pramipexole treatment of restless legs syndrome (RLS). Sleep medicine 20040101
Role of dopamine receptor agonists in the treatment of restless legs syndrome. CNS drugs 20040101
Predictors of impaired daytime sleep and wakefulness in patients with Parkinson disease treated with older (ergot) vs newer (nonergot) dopamine agonists. Archives of neurology 20040101
Quality of life in early Parkinson's disease: impact of dyskinesias and motor fluctuations. Movement disorders : official journal of the Movement Disorder Society 20040101
[A comparative study of efficacy of dopamine receptors agonists and catechol-O-methyltransferase in the treatment of late stages of Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101
Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists. Neurotoxicity research 20040101
Low-dose pramipexole in the management of restless legs syndrome. An open label trial. Neuropsychobiology 20040101
Restless legs symptoms in a patient with above knee amputations: a case of phantom restless legs. Clinical neuropharmacology 20040101
Pramipexole v. levodopa as initial treatment for Parkinson's disease: a randomized clinical-economic trial. Medical decision making : an international journal of the Society for Medical Decision Making 20040101
Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D3 receptor. BMC biology 20040101
Pramipexole in treatment-resistant depression: an extended follow-up. Depression and anxiety 20040101
Vasculitis and nephritis caused by pramipexole, a second generation dopamine agonist. Clinical and experimental rheumatology 20040101
Efficacy, safety, and tolerability of pramipexole in untreated and levodopa-treated patients with Parkinson's disease. Journal of the neurological sciences 20031215
Pramipexole in Restless Legs syndrome. Evaluation by suggested immobilization test. Journal of neurology 20031201
Fibromyalgia and pramipexole: promise and precaution. The Journal of rheumatology 20031201
Comparing dopamine agonists in Parkinson's disease. Current opinion in neurology 20031201
Diagnosis and treatment of sleep disorders: a brief review for clinicians. Dialogues in clinical neuroscience 20031201
The effects of pramipexole in REM sleep behavior disorder. Neurology 20031125
Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor. The Journal of biological chemistry 20031121
Potent activation of dopamine D3/D2 heterodimers by the antiparkinsonian agents, S32504, pramipexole and ropinirole. Journal of neurochemistry 20031101
Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole. Experimental neurology 20031101
Randomized, double-blind, 3-month parallel study of the effects of pramipexole, pergolide, and placebo on Parkinsonian tremor. Movement disorders : official journal of the Movement Disorder Society 20031101
Pramipexole in the management of restless legs syndrome: an extended study. Sleep 20031101
3,4-methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates. The Journal of neuroscience : the official journal of the Society for Neuroscience 20031008
Current treatment options for restless legs syndrome. Expert opinion on pharmacotherapy 20031001
Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum. Journal of neural transmission (Vienna, Austria : 1996) 20031001
Randomized, double-blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20031001
Sleep attacks in Parkinson's disease: a clinical and polysomnographic study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20031001
Oral anticoagulation for ECG tremor artefact simulating atrial fibrillation. Acta cardiologica 20031001
Clinical strategies to prevent and delay motor complications. Neurology 20030923
Treatment effects on nigrostriatal projection integrity in partial 6-OHDA lesions: comparison of L-DOPA and pramipexole. Experimental neurology 20030901
The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment. Dialogues in clinical neuroscience 20030901
Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms. European journal of pharmacology 20030815
Pathological gambling associated with dopamine agonist therapy in Parkinson's disease. Neurology 20030812
Pramipexole increases vesicular dopamine uptake: implications for treatment of Parkinson's neurodegeneration. European journal of pharmacology 20030808
Current status of Parkinson's disease treatment in Korea. Parkinsonism & related disorders 20030801
Neuroprotective mechanisms of antiparkinsonian dopamine D2-receptor subfamily agonists. Neurochemical research 20030701
REAL and CALM: what have we learned? Movement disorders : official journal of the Movement Disorder Society 20030701
Pramipexole and pergolide in the treatment of depression in Parkinson's disease: a national multicentre prospective randomized study. European journal of neurology 20030701
Dual dopamine agonist treatment in Parkinson's disease. Journal of neurology 20030701
Parkinson's disease: is the initial treatment established? Current neurology and neuroscience reports 20030701
Assessment of sleepiness and unintended sleep in Parkinson's disease patients taking dopamine agonists. Sleep medicine 20030701
The use of dopamine enhancing medications with children in low response states following brain injury. Brain injury 20030601
The increased utilisation of dopamine agonists and the introduction of COMT inhibitors have not reduced levodopa consumption--a nation-wide perspective in Sweden. Parkinsonism & related disorders 20030601
Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20030601
Dopamine agonist therapy for hyperprolactinemia. Clinical obstetrics and gynecology 20030601
[Treatment of restless legs syndrome in uremic patients undergoing dialysis with pramipexole: preliminary results]. Revista medica de Chile 20030601
Reduction of oxidative stress in amyotrophic lateral sclerosis following pramipexole treatment. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20030601
Dihydroergocriptine in Parkinson's disease: clinical efficacy and comparison with other dopamine agonists. Acta neurologica Scandinavica 20030501
The initial drug treatment of older patients with Parkinson's disease - consider an agonist, but don't demonise dopa. Age and ageing 20030501
Efficacy, safety and cost of new drugs acting on the central nervous system. European journal of clinical pharmacology 20030501
Pramipexole in comparison to l-dopa: a neuropsychological study. Journal of neural transmission (Vienna, Austria : 1996) 20030401
[(123)I]beta-CIT SPECT is a useful method for monitoring dopaminergic degeneration in early stage Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry 20030301
Slowing Parkinson's disease progression: recent dopamine agonist trials. Neurology 20030211
Double-blind, single-dose, cross-over study of the effects of pramipexole, pergolide, and placebo on rest tremor and UPDRS part III in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20030201
Piribedil-induced sleep attacks in Parkinson's disease. Fundamental & clinical pharmacology 20030201
Sleep attacks--facts and fiction: a critical review. Advances in neurology 20030101
Dopamine agonists induce episodes of irresistible daytime sleepiness. European neurology 20030101
Sleepwalking and sleep terrors in prepubertal children: what triggers them? Pediatrics 20030101
Loss of color vision during long-term treatment with pramipexole. Journal of neurology 20030101
Multiple blood donations associated with iron deficiency in patients with restless legs syndrome. Mayo Clinic proceedings 20030101
Comparison of the risk of adverse events with pramipexole and ropinirole in patients with Parkinson's disease: a meta-analysis. Drug safety 20030101
Inhibitory effects of D2 agonists by striatal injection on excessive release of dopamine and hyperactivity induced by Bay K 8644 in rats. Neuroscience 20030101
Advances in the pharmacological management of Parkinson disease. Journal of neural transmission. Supplementum 20030101
Cabergoline, pramipexole and ropinirole used as monotherapy in early Parkinson's disease: an evidence-based comparison. Drugs & aging 20030101
Pramipexole in routine clinical practice: a prospective observational trial in Parkinson's disease. CNS drugs 20030101
Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics. Neurology 20021224
Dopamine agonist monotherapy in Parkinson's disease. Lancet (London, England) 20021130
Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes. The Journal of pharmacology and experimental therapeutics 20021101
Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor. The Journal of pharmacology and experimental therapeutics 20021101
Dopamine agonists and neuroprotection in Parkinson's disease. European journal of neurology 20021101
Do dopamine agonists or levodopa modify Parkinson's disease progression? European journal of neurology 20021101
Restless legs syndrome augmentation and pramipexole treatment. Sleep medicine 20021101
Effect of daily dosing duration of direct and indirect dopamine receptor agonists: cocaine cross-tolerance following chronic regimens. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20021001
Potential antidepressant properties of pramipexole detected in locomotor and operant behavioral investigations in mice. Psychopharmacology 20021001
An evidence-based review of dopamine receptor agonists in the treatment of Parkinson's disease. Saudi medical journal 20021001
Pramipexole in treatment-resistant depression: a 16-week naturalistic study. Bipolar disorders 20021001
Neuroprotection in idiopathic Parkinson's disease. Journal of neurology 20021001
Fused azaindole derivatives: molecular design, synthesis and in vitro pharmacology leading to the preferential dopamine D3 receptor agonist FAUC 725. Bioorganic & medicinal chemistry letters 20020902
Combination of two different dopamine agonists in the management of Parkinson's disease. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20020901
Two advances in the management of Parkinson disease. Cleveland Clinic journal of medicine 20020801
[The usefulness of dopaminergic drugs in traumatic brain injury]. Revista de neurologia 20020801
Acute placebo-controlled sleep laboratory studies and clinical follow-up with pramipexole in restless legs syndrome. European archives of psychiatry and clinical neuroscience 20020801
[Pramipexole in Parkinson disease. Results of a treatment observation]. Der Nervenarzt 20020801
Brain imaging to assess the effects of dopamine agonists on progression of Parkinson disease. JAMA 20020717
The effects of speech therapy and pharmacological treatments on voice and speech in Parkinson s disease: a review of the literature. Current medicinal chemistry 20020701
Sleep attacks in patients taking dopamine agonists: review. BMJ (Clinical research ed.) 20020622
Pramipexole in patients with Parkinson's disease and marked drug resistant tremor: a randomised, double blind, placebo controlled multicentre study. Journal of neurology, neurosurgery, and psychiatry 20020601
[Multiple latency test in a patient with episodes of sleep induced by pergolide]. Revista de neurologia 20020601
Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics. Neurology 20020514
[Dopamine agonist is effective in Parkinson disease not only against tremor. Depression is also improved]. MMW Fortschritte der Medizin 20020506
A case of Parkinsonism due to lithium intoxication: treatment with Pramipexole. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20020501
Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression. JAMA 20020403
Alopecia induced by dopamine agonists. Neurology 20020312
Influence of sildenafil on copulatory behaviour in sluggish or normal ejaculator male rats: a central dopamine mediated effect? Neuropharmacology 20020301
Neuroprotection and dopamine agonists. Neurology 20020226
Long-term studies of dopamine agonists. Neurology 20020226
Restless legs syndrome: treatment with dopaminergic agents. Neurology 20020226
Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma. Journal of neuroscience research 20020215
Pramipexole for depression. The American journal of psychiatry 20020201
A review of pramipexole and its clinical utility in Parkinson's disease. Expert opinion on pharmacotherapy 20020201
[Rapid-eye-movement sleep disorders in Parkinson's disease]. Revue neurologique 20020201
Excessive daytime sleepiness and sudden-onset sleep in Parkinson disease: a survey by the Canadian Movement Disorders Group. JAMA 20020101
Pergolide in the treatment of patients with early and advanced Parkinson's disease. Clinical neuropharmacology 20020101
Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington's disease. Clinical neuropharmacology 20020101
Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease. Clinical pharmacokinetics 20020101
'Sleep attacks' or 'unintended sleep episodes' occur with dopamine agonists: is this a class effect? Drug safety 20020101
[Rhabdomyolysis as a complication of Parkinson's disease]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20020101
Choosing the right dopamine agonist for patients with Parkinson's disease. Current medical research and opinion 20020101
Review: selegiline improves symptoms and levodopa is better than pramipexole for motor function in untreated Parkinson disease. ACP journal club 20020101
DA agonists -- non-ergot derivatives: pramipexole: management of Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20020101
[Use of dopamine agonists in the treatment of Parkinson's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101
Sleep disorders in Parkinson's disease: epidemiology and management. Drugs & aging 20020101
Restless legs syndrome in the older adult: diagnosis and management. Drugs & aging 20020101
Pramipexole in Parkinson's disease. A short-term study using the combined levodopa-dopamine agonist test. Functional neurology 20020101
Daytime sleepiness and other sleep disorders in Parkinson's disease. Neurology 20011023
Pramipexole: a nonergot dopamine agonist as drug therapy in Parkinson's disease. Expert review of neurotherapeutics 20010901
Current advances in Parkinson's disease. Trends in neurosciences 20010701
Modafinil and pramipexole-associated somnolence. Movement disorders : official journal of the Movement Disorder Society 20010701
Adjunctive dopamine agonists in treatment-resistant bipolar II depression: an open case series. Pharmacopsychiatry 20010701
Neuroprotective effects of pramipexole in young and aged MPTP-treated mice. Brain research 20010629
Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD. Neurology 20010612
Newer dopamine agonists in the treatment of restless legs syndrome. The Annals of pharmacotherapy 20010501
Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole. European journal of pharmacology 20010406
Antiparkinsonian drugs and 'sleep attacks'. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010403
Pramipexole augmentation in panic with agoraphobia. The American journal of psychiatry 20010301
Antagonism of the discriminative stimulus effects of (+)-7-OH-DPAT by remoxipride but not PNU-99194A. Pharmacology, biochemistry, and behavior 20010301
Current and emerging treatments in Parkinson's disease. Annals of the Academy of Medicine, Singapore 20010301
Possible applications for dopaminergic agents following traumatic brain injury: part 2. The Journal of head trauma rehabilitation 20010201
Efficacy and tolerability of dopamine agonists in a parkinsonian population. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20010201
Switching from pergolide to pramipexole in patients with Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996) 20010101
A study of excessive daytime sleepiness and its clinical significance in three groups of Parkinson's disease patients taking pramipexole, cabergoline and levodopa mono and combination therapy. Journal of neural transmission (Vienna, Austria : 1996) 20010101
Dopamine agonists. Seminars in neurology 20010101
Are dopamine receptor agonists neuroprotective in Parkinson's disease? Drugs & aging 20010101
Sleep disorders in patients with Parkinson's disease: epidemiology and management. CNS drugs 20010101
Economic and health-related quality of life considerations of new therapies in Parkinson's disease. PharmacoEconomics 20010101
Increased risk of somnolence with the new dopamine agonists in patients with Parkinson's disease: a meta-analysis of randomised controlled trials. Drug safety 20010101
Does combined treatment with novel antidepressants and a dopamine D3 receptor agonist reproduce cocaine discrimination in rats? Polish journal of pharmacology 20010101
Locomotor hypoactivity and motor disturbances--behavioral effects induced by intracerebellar microinjections of dopaminergic DA-D2/D3 receptor agonists. Polish journal of pharmacology 20010101
[Dopaminergic agonists in the treatment of Parkinson's disease]. Revue medicale de Bruxelles 20001201
['Sleep attacks' in Parkinson patients. A side effect of nonergoline dopamine agonists or a class effect of dopamine agonists?]. Der Nervenarzt 20000801
Pramipexole-induced somnolence and episodes of daytime sleep. Movement disorders : official journal of the Movement Disorder Society 20000701
Discriminative stimulus properties of the dopamine D3 receptor agonists, PD128,907 and 7-OH-DPAT: a comparative characterization with novel ligands at D3 versus D2 receptors. Neuropharmacology 20000214
Role of dopamine D3 receptors in thermoregulation: a reappraisal. Neuroreport 20000117
Clinical pharmacology of dopamine agonists. Pharmacotherapy 20000101
Efficacy of pramipexole, a new dopamine receptor agonist, to relieve the parkinsonian-like muscle rigidity in rats. European journal of pharmacology 19991126
Pramipexole treatment for cocaine cravings. The American journal of psychiatry 19991101
Effects of pramipexole on contraversive rotation and functional motor impairments in 1-methyl-4-phenyl1,2,3, 6-tetrahydropyridine-induced chronic hemiparkinsonian monkeys. The Journal of pharmacology and experimental therapeutics 19981201
Involvement of dopamine D2 receptors in the effect of cocaine on sexual behaviour and stretching-yawning of male rats. Neuropharmacology 19970601
The behavioural effects of pramipexole, a novel dopamine receptor agonist. European journal of pharmacology 19970411
Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors. European journal of pharmacology 19950623
A functional test identifies dopamine agonists selective for D3 versus D2 receptors. Neuroreport 19950126
Effects of several partial dopamine D2 receptor agonists in Cebus apella monkeys previously treated with haloperidol. European journal of pharmacology 19930624
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