Home Other Building Blocks (S)-1,1-Diphenylprolinol

(S)-1,1-Diphenylprolinol

CAS No.:
112068-01-6
Catalog Number:
AG003CE0
Molecular Formula:
C17H19NO
Molecular Weight:
253.3389
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$13
- +
5g
98%
In Stock USA
United States
$19
- +
25g
98%
In Stock USA
United States
$57
- +
100g
98%
In Stock USA
United States
$132
- +
Product Description
Catalog Number:
AG003CE0
Chemical Name:
(S)-1,1-Diphenylprolinol
CAS Number:
112068-01-6
Molecular Formula:
C17H19NO
Molecular Weight:
253.3389
MDL Number:
MFCD00075506
IUPAC Name:
diphenyl-[(2S)-pyrrolidin-2-yl]methanol
InChI:
InChI=1S/C17H19NO/c19-17(16-12-7-13-18-16,14-8-3-1-4-9-14)15-10-5-2-6-11-15/h1-6,8-11,16,18-19H,7,12-13H2/t16-/m0/s1
InChI Key:
OGCGXUGBDJGFFY-INIZCTEOSA-N
SMILES:
OC(c1ccccc1)(c1ccccc1)[C@@H]1CCCN1
EC Number:
601-153-1
Properties
Complexity:
261  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
253.147g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
253.345g/mol
Monoisotopic Mass:
253.147g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
32.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.7  
Literature
Title Journal
2-DPMP (desoxypipradrol, 2-benzhydrylpiperidine, 2-phenylmethylpiperidine) and D2PM (diphenyl-2-pyrrolidin-2-yl-methanol, diphenylprolinol): A preliminary review. Progress in neuro-psychopharmacology & biological psychiatry 20121203
Use and acute toxicity associated with the novel psychoactive substances diphenylprolinol (D2PM) and desoxypipradrol (2-DPMP). Clinical toxicology (Philadelphia, Pa.) 20120901
'Legal highs'--novel and emerging psychoactive drugs: a chemical overview for the toxicologist. Clinical toxicology (Philadelphia, Pa.) 20120101
Clinical toxicology of newer recreational drugs. Clinical toxicology (Philadelphia, Pa.) 20111001
Formation and stability of prolinol and prolinol ether enamines by NMR: delicate selectivity and reactivity balances and parasitic equilibria. Journal of the American Chemical Society 20110511
Organocatalytic approach to polysubstituted piperidines and tetrahydropyrans. Organic letters 20110401
Recreational drugs, 3,4-Methylenedioxymethamphetamine(MDMA), 3,4-methylenedioxyamphetamine (MDA) and diphenylprolinol, inhibit neurite outgrowth in PC12 cells. The Journal of toxicological sciences 20100601
Direct oxidation of beta-aryl substituted aldehydes to alpha,beta-unsaturated aldehydes promoted by an o-anisidine-Pd(OAc)2 co-catalyst. Chemistry, an Asian journal 20091102
Spiroborate ester-mediated asymmetric synthesis of beta-hydroxy ethers and its conversion to highly enantiopure beta-amino ethers. The Journal of organic chemistry 20090605
Catalytic asymmetric oxa-Michael-Michael cascade for facile construction of chiral chromans via an aminal intermediate. Organic letters 20090402
Highly enantio- and diastereoselective organocatalytic cascade aza-Michael-Michael reactions: a direct method for the synthesis of trisubstituted chiral pyrrolidines. Chemical communications (Cambridge, England) 20081121
Cardiovascular toxicity associated with recreational use of diphenylprolinol (diphenyl-2-pyrrolidinemethanol [D2PM]). Journal of medical toxicology : official journal of the American College of Medical Toxicology 20080901
Synthesis of a new C(2)-symmetric chiral catalyst and its application in the catalytic asymmetric borane reduction of prochiral ketones. Chirality 20080201
Organocatalytic enantioselective cascade Michael-alkylation reactions: synthesis of chiral cyclopropanes and investigation of unexpected organocatalyzed stereoselective ring opening of cyclopropanes. Journal of the American Chemical Society 20070905
Enantioselective organocatalytic double Michael addition reactions. Organic letters 20070426
Chiral Diphenylprolinol TES ether promoted conjugate addition-aldol-dehydration reactions between alpha,beta-unsaturated aldehydes and 2-N-protected amino benzaldehydes. Organic letters 20070315
Chiral diphosphites and diphosphoramidites as cheap and efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation. Chemical communications (Cambridge, England) 20060604
Enantioselective addition of diethylzinc to aldehydes catalyzed by optically active C2-symmetrical bis-beta-amino alcohols. Chirality 20021001
Properties