Home Other Building Blocks L-Selenocystine monohydrate

L-Selenocystine monohydrate

CAS No.:
29621-88-3
Catalog Number:
AG003C8X
Molecular Formula:
C6H12N2O4Se2
Molecular Weight:
334.0905
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
50mg
≥90%
1 week
United States
$91
- +
100mg
≥90%
1 week
United States
$123
- +
250mg
≥90%
1 week
United States
$214
- +
1g
≥90%
1 week
United States
$300
- +
Product Description
Catalog Number:
AG003C8X
Chemical Name:
L-Selenocystine monohydrate
CAS Number:
29621-88-3
Molecular Formula:
C6H12N2O4Se2
Molecular Weight:
334.0905
MDL Number:
MFCD27977198
IUPAC Name:
(2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]diselanyl]propanoic acid
InChI:
InChI=1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1
InChI Key:
JULROCUWKLNBSN-IMJSIDKUSA-N
SMILES:
NC(C(=O)O)C[Se][Se]C[C@@H](C(=O)O)N
EC Number:
608-382-6
UNII:
261B157KR8
Properties
Complexity:
192  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
335.913g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
334.114g/mol
Monoisotopic Mass:
335.913g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
127A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Molecular mechanisms involved in the protective effect of selenocystine against methylmercury-induced cell death in human HepG2 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130901
Combination of chemometrically assisted voltammetry, calorimetry, and circular dichroism as a new method for the study of bioinorganic substances: application to selenocystine metal complexes. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120201
Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture. The Journal of nutritional biochemistry 20111001
Selenium bioaccumulation and speciation in Chironomus dilutus exposed to water-borne selenate, selenite, or seleno-DL-methionine. Environmental toxicology and chemistry 20111001
Hepatoprotective, immunomodulatory, and anti-inflammatory activities of selenocystine in experimental liver injury of rats. Biological trace element research 20110901
Distribution of Se and its species in Myriophyllum spicatum and Ceratophyllum demersum growing in water containing Se (VI). Chemosphere 20110901
Anti-hemolytic and peroxyl radical scavenging activity of organoselenium compounds: an in vitro study. Biological trace element research 20110501
Protective effects of selenocystine against γ-radiation-induced genotoxicity in Swiss albino mice. Radiation and environmental biophysics 20110501
Preventing metal-mediated oxidative DNA damage with selenium compounds. Metallomics : integrated biometal science 20110501
Fast cleavage of a diselenide induced by a platinum(II)-methionine complex and its biological implications. Journal of inorganic biochemistry 20101101
Simultaneous analysis of mercury and selenium species including chiral forms of selenomethionine in human urine and serum by HPLC column-switching coupled to ICP-MS. The Analyst 20101001
Synthesis of unnatural selenocystines and beta-aminodiselenides via regioselective ring-opening of sulfamidates using a sequential, one-pot, multistep strategy. The Journal of organic chemistry 20100507
Molecularly defined antibody conjugation through a selenocysteine interface. Biochemistry 20091222
Electrochemical oxidation of selenocystine and selenomethionine. Colloids and surfaces. B, Biointerfaces 20091101
In vitro radioprotection studies of organoselenium compounds: differences between mono- and diselenides. Radiation and environmental biophysics 20091101
No selenium required: reactions catalyzed by mammalian thioredoxin reductase that are independent of a selenocysteine residue. Biochemistry 20090707
Selenocystine induces caspase-independent apoptosis in MCF-7 human breast carcinoma cells with involvement of p53 phosphorylation and reactive oxygen species generation. The international journal of biochemistry & cell biology 20090301
Selenocystine induces reactive oxygen species-mediated apoptosis in human cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090201
Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylation. Journal of agricultural and food chemistry 20081126
Selenocystine induces apoptosis of A375 human melanoma cells by activating ROS-mediated mitochondrial pathway and p53 phosphorylation. Cellular and molecular life sciences : CMLS 20080901
Nanoparticulate glutathione peroxidase mimics based on selenocystine-pullulan conjugates. Bioconjugate chemistry 20080901
A novel HPLC-UV/nano-TiO2-chemiluminescence system for the determination of selenocystine and selenomethionine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080715
Pulse radiolysis studies on reactions of hydroxyl radicals with selenocystine derivatives. The journal of physical chemistry. B 20080410
Elution behavior of diaminopimelic acid and related diamino acids using the advanced Marfey's method. Journal of chromatography. A 20070810
New separation method for organic and inorganic selenium compounds based on anion exchange chromatography followed by inductively coupled plasma mass spectrometry. Analytical and bioanalytical chemistry 20060801
Effects of selenocystine on lead-exposed Chinese hamster ovary (CHO) and PC-12 cells. Toxicology and applied pharmacology 20060715
Direct amino acid analysis method for speciation of selenoamino acids using high-performance anion-exchange chromatography coupled with integrated pulsed amperometric detection. Journal of chromatography. A 20060616
Selenium speciation by high-performance anion-exchange chromatography-post-column UV irradiation coupled with atomic fluorescence spectrometry. Journal of chromatography. A 20060616
The electrochemical reaction mechanism of selenocystine on selenium-gold film modified glassy carbon electrode. Colloids and surfaces. B, Biointerfaces 20060501
Effect of pH on one-electron oxidation chemistry of organoselenium compounds in aqueous solutions. The journal of physical chemistry. A 20060209
The central role of metal coordination in selenium antioxidant activity. Inorganic chemistry 20060123
Effect of the chemical form of supranutritional selenium on selenium load and selenoprotein activities in virgin, pregnant, and lactating rats. Journal of animal science 20050201
Synthesis of single- and multiple-stranded cystine-rich peptides. Biopolymers 20050101
Study of selenium distribution in the protein fractions of the Brazil nut, Bertholletia excelsa. Journal of agricultural and food chemistry 20040630
Induction of the mitochondrial permeability transition by selenium compounds mediated by oxidation of the protein thiol groups and generation of the superoxide. Biochemical pharmacology 20031215
Mouse methionine sulfoxide reductase B: effect of selenocysteine incorporation on its activity and expression of the seleno-containing enzyme in bacterial and mammalian cells. Biochemical and biophysical research communications 20021004
Characterization of selenium species in Brazil nuts by HPLC-ICP-MS and ES-MS. Journal of agricultural and food chemistry 20020925
Solid-phase extraction for the simultaneous preconcentration of organic (selenocystine) and inorganic [Se(IV), Se(VI)] selenium in natural waters. Journal of chromatography. A 20020719
Transport measurements across Caco-2 monolayers of different organic and inorganic selenium: influence of sulfur compounds. Biological trace element research 20011201
Properties