Home Other Building Blocks (E)-5-(2-Bromovinyl)pyrimidine-2,4(1H,3H)-dione

(E)-5-(2-Bromovinyl)pyrimidine-2,4(1H,3H)-dione

CAS No.:
69304-49-0
Catalog Number:
AG003C0T
Molecular Formula:
C6H5BrN2O2
Molecular Weight:
217.0201
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
≥95%
1 week
United States
$126
- +
50mg
≥95%
1 week
United States
$175
- +
100mg
≥95%
1 week
United States
$279
- +
250mg
≥95%
1 week
United States
$397
- +
Product Description
Catalog Number:
AG003C0T
Chemical Name:
(E)-5-(2-Bromovinyl)pyrimidine-2,4(1H,3H)-dione
CAS Number:
69304-49-0
Molecular Formula:
C6H5BrN2O2
Molecular Weight:
217.0201
MDL Number:
MFCD00132885
IUPAC Name:
5-[(E)-2-bromoethenyl]-1H-pyrimidine-2,4-dione
InChI:
InChI=1S/C6H5BrN2O2/c7-2-1-4-3-8-6(11)9-5(4)10/h1-3H,(H2,8,9,10,11)/b2-1+
InChI Key:
BLXGZIDBSXVMLU-OWOJBTEDSA-N
SMILES:
Br/C=C/c1c[nH]c(=O)[nH]c1=O
Properties
Complexity:
257  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
215.953g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
217.022g/mol
Monoisotopic Mass:
215.953g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
58.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.1  
Literature
Title Journal
Relationships among plasma [2-(13)C]uracil concentrations, breath (13)CO(2) expiration, and dihydropyrimidine dehydrogenase (DPD) activity in the liver in normal and dpd-deficient dogs. Drug metabolism and disposition: the biological fate of chemicals 20050301
[Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020801
Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase. Molecular pharmacology 20020501
Synthesis and antiviral activity of (E)-5-(2-bromovinyl)uracil and (E)-5-(2-bromovinyl)uridine. Journal of medicinal chemistry 19860201
Properties