Home Sulfos (2E)-3-[(4-Methylbenzene)sulfonyl]prop-2-enenitrile

(2E)-3-[(4-Methylbenzene)sulfonyl]prop-2-enenitrile

CAS No.:
19542-67-7
Catalog Number:
AG003C0J
Molecular Formula:
C10H9NO2S
Molecular Weight:
207.2490
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
95%
In Stock USA
United States
$300
- +
500mg
95%
In Stock USA
United States
$450
- +
1g
95%
In Stock USA
United States
$750
- +
Product Description
Catalog Number:
AG003C0J
Chemical Name:
(2E)-3-[(4-Methylbenzene)sulfonyl]prop-2-enenitrile
CAS Number:
19542-67-7
Molecular Formula:
C10H9NO2S
Molecular Weight:
207.2490
MDL Number:
MFCD00712162
IUPAC Name:
(E)-3-(4-methylphenyl)sulfonylprop-2-enenitrile
InChI:
InChI=1S/C10H9NO2S/c1-9-3-5-10(6-4-9)14(12,13)8-2-7-11/h2-6,8H,1H3/b8-2+
InChI Key:
DOEWDSDBFRHVAP-KRXBUXKQSA-N
SMILES:
N#C/C=C/S(=O)(=O)c1ccc(cc1)C
UNII:
4Y5G2A4F6O
Properties
Complexity:
347  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
207.035g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
207.247g/mol
Monoisotopic Mass:
207.035g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
66.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.4  
Literature
Title Journal
Variation in doses and duration of particulate matter exposure in bronchial epithelial cells results in upregulation of different genes associated with airway disorders. Toxicology in vitro : an international journal published in association with BIBRA 20180901
MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis. Archives of toxicology 20180901
Licoricidin enhances gemcitabine-induced cytotoxicity in osteosarcoma cells by suppressing the Akt and NF-κB signal pathways. Chemico-biological interactions 20180625
Acrylamide-induced oxidative stress and inflammatory response are alleviated by N-acetylcysteine in PC12 cells: Involvement of the crosstalk between Nrf2 and NF-κB pathways regulated by MAPKs. Toxicology letters 20180515
Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype. Chemico-biological interactions 20180301
Nitro-fatty acid inhibition of triple-negative breast cancer cell viability, migration, invasion, and tumor growth. The Journal of biological chemistry 20180126
Intravasation of SW620 colon cancer cell spheroids through the blood endothelial barrier is inhibited by clinical drugs and flavonoids in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180101
NF-κB-vimentin is involved in steroidogenesis stimulated by mono-butyl phthalate in primary cultured ovarian granulosa cells. Toxicology in vitro : an international journal published in association with BIBRA 20171201
PKA/CREB and NF-κB pathway regulates AKNA transcription: A novel insight into T-2 toxin-induced inflammation and GH deficiency in GH3 cells. Toxicology 20171201
Bisphenol A induces COX-2 through the mitogen-activated protein kinase pathway and is associated with levels of inflammation-related markers in elderly populations. Environmental research 20171001
Promotion of Wilms' tumor cells migration and invasion by mono-2-ethyhexyl phthalate (MEHP) via activation of NF-κB signals. Chemico-biological interactions 20170525
From the Cover: Activation of NF-κB-Autophagy Axis by 2-Hydroxyethyl Methacrylate Commits Dental Mesenchymal Cells to Apoptosis. Toxicological sciences : an official journal of the Society of Toxicology 20170501
Bisphenol A suppresses glucocorticoid target gene (ENaCγ) expression via a novel ERβ/NF-κB/GR signalling pathway in lung epithelial cells. Archives of toxicology 20170401
Curcumin Inhibits 5-Fluorouracil-induced Up-regulation of CXCL1 and CXCL2 of the Colon Associated with Attenuation of Diarrhoea Development. Basic & clinical pharmacology & toxicology 20161201
Trikatu, an herbal compound ameliorates rheumatoid arthritis by the suppression of inflammatory immune responses in rats with adjuvant-induced arthritis and on cultured fibroblast like synoviocytes via the inhibition of the NFκB signaling pathway. Chemico-biological interactions 20161025
2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells. Archives of toxicology 20160901
Carbon monoxide releasing molecule-2 ameliorates IL-1β-induced IL-8 in human gastric cancer cells. Toxicology 20160615
Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. Toxicology and applied pharmacology 20160601
Gallic acid abolishes the EGFR/Src/Akt/Erk-mediated expression of matrix metalloproteinase-9 in MCF-7 breast cancer cells. Chemico-biological interactions 20160525
Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein. The Journal of biological chemistry 20160212
PM2.5-induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF-κB-dependent pathway. Journal of applied toxicology : JAT 20160101
Vimentin-Mediated Steroidogenesis Induced by Phthalate Esters: Involvement of DNA Demethylation and Nuclear Factor κB. PloS one 20160101
Diesel Exhaust Particles Upregulate Interleukins IL-6 and IL-8 in Nasal Fibroblasts. PloS one 20160101
Cadmium induces matrix metalloproteinase-9 expression via ROS-dependent EGFR, NF-кB, and AP-1 pathways in human endothelial cells. Toxicology 20151202
Nickel may contribute to EGFR mutation and synergistically promotes tumor invasion in EGFR-mutated lung cancer via nickel-induced microRNA-21 expression. Toxicology letters 20150819
Tetramethylpyrazine (TMP) protects against sodium arsenite-induced nephrotoxicity by suppressing ROS production, mitochondrial dysfunction, pro-inflammatory signaling pathways and programed cell death. Archives of toxicology 20150701
Cyclosporin A upregulates ETB receptor in vascular smooth muscle via activation of mitogen-activating protein kinases and NF-κB pathways. Toxicology letters 20150519
Antroquinonol from Antrodia Camphorata suppresses breast tumor migration/invasion through inhibiting ERK-AP-1- and AKT-NF-κB-dependent MMP-9 and epithelial-mesenchymal transition expressions. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150401
The role of NF-κB signaling pathway in polyhexamethylene guanidine phosphate induced inflammatory response in mouse macrophage RAW264.7 cells. Toxicology letters 20150304
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis. Molecular cell 20141023
Long-term low-dose exposure of human urothelial cells to sodium arsenite activates lipocalin-2 via promoter hypomethylation. Archives of toxicology 20140801
Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species. Free radical biology & medicine 20140801
Lipopolysaccharide-induced microRNA-146a targets CARD10 and regulates angiogenesis in human umbilical vein endothelial cells. Toxicological sciences : an official journal of the Society of Toxicology 20140801
Preferential expression of PAPPA in human preadipocytes from omental fat. The Journal of endocrinology 20140701
Subneurotoxic copper(II)-induced NF-κB-dependent microglial activation is associated with mitochondrial ROS. Toxicology and applied pharmacology 20140415
Apigenin potentiates the growth inhibitory effects by IKK-β-mediated NF-κB activation in pancreatic cancer cells. Toxicology letters 20140103
Cytoprotective effect of kaempferol on paraquat-exposed BEAS-2B cells via modulating expression of MUC5AC. Biological & pharmaceutical bulletin 20140101
Crucial role of Toll-like receptors in the zinc/nickel-induced inflammatory response in vascular endothelial cells. Toxicology and applied pharmacology 20131215
Induction of steroid sulfatase expression in PC-3 human prostate cancer cells by insulin-like growth factor II. Toxicology letters 20131125
Ethanol increases matrix metalloproteinase-12 expression via NADPH oxidase-dependent ROS production in macrophages. Toxicology and applied pharmacology 20131115
NADPH oxidase/ROS-dependent PYK2 activation is involved in TNF-α-induced matrix metalloproteinase-9 expression in rat heart-derived H9c2 cells. Toxicology and applied pharmacology 20131015
NF-κB-mediated inflammation leading to EMT via miR-200c is involved in cell transformation induced by cigarette smoke extract. Toxicological sciences : an official journal of the Society of Toxicology 20131001
Immunostimulatory activity of polysaccharides from Cheonggukjang. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130901
Apoptosis induced by trimethyltin chloride in human neuroblastoma cells SY5Y is regulated by a balance and cross-talk between NF-κB and MAPKs signaling pathways. Archives of toxicology 20130701
Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis. Archives of toxicology 20130701
Interaction of inflammatory and anti-inflammatory responses in microglia by Staphylococcus aureus-derived lipoteichoic acid. Toxicology and applied pharmacology 20130515
The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system. The Biochemical journal 20130501
Diclofenac enhances proinflammatory cytokine-induced phagocytosis of cultured microglia via nitric oxide production. Toxicology and applied pharmacology 20130415
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. The Biochemical journal 20130415
A novel interleukin 33/ST2 signaling regulates inflammatory response in human corneal epithelium. PloS one 20130101
TNF-Α may mediate inflammasome activation in the absence of bacterial infection in more than one way. PloS one 20130101
Yu Ping Feng San, an ancient Chinese herbal decoction containing Astragali Radix, Atractylodis Macrocephalae Rhizoma and Saposhnikoviae Radix, regulates the release of cytokines in murine macrophages. PloS one 20130101
Expression of macrophage migration inhibitory factor by osteoblastic cells: protection against cadmium toxicity. Toxicology letters 20121217
Inflammatory regulation of ATP binding cassette efflux transporter expression and function in microglia. The Journal of pharmacology and experimental therapeutics 20121201
Cytokine expression in trichloroethylene-induced hypersensitivity dermatitis: an in vivo and in vitro study. Toxicology letters 20121123
Opposed arsenite-mediated regulation of p53-survivin is involved in neoplastic transformation, DNA damage, or apoptosis in human keratinocytes. Toxicology 20121028
Changes in mitochondrial DNA alter expression of nuclear encoded genes associated with tumorigenesis. Experimental cell research 20121015
Protective role of quercetin against lead-induced inflammatory response in rat kidney through the ROS-mediated MAPKs and NF-κB pathway. Biochimica et biophysica acta 20121001
NF-κΒ inhibition is ineffective in blocking cytokine-induced IL-8 production but P38 and STAT1 inhibitors are effective. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120901
The role of endothelial cell adhesion molecules P-selectin, E-selectin and intercellular adhesion molecule-1 in leucocyte recruitment induced by exogenous methylglyoxal. Immunology 20120901
TNFR1-dependent pulmonary apoptosis during ischemic acute kidney injury. American journal of physiology. Lung cellular and molecular physiology 20120901
Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea. Bioorganic & medicinal chemistry letters 20120901
Activation of neurokinin-1 receptors up-regulates substance P and neurokinin-1 receptor expression in murine pancreatic acinar cells. Journal of cellular and molecular medicine 20120701
Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents. Journal of medicinal chemistry 20120628
Pro-inflammatory NF-κB and early growth response gene 1 regulate epithelial barrier disruption by food additive carrageenan in human intestinal epithelial cells. Toxicology letters 20120620
Prostanoid EP₁ receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB. British journal of pharmacology 20120601
Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway. Carcinogenesis 20120601
Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-κB, and MAPK pathways. Archives of toxicology 20120601
Inhibiting NF-κB in the developing lung disrupts angiogenesis and alveolarization. American journal of physiology. Lung cellular and molecular physiology 20120515
Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501
Suppression of NF-κB and NF-κB regulated oxidative stress and neuroinflammation by BAY 11-7082 (IκB phosphorylation inhibitor) in experimental diabetic neuropathy. Biochimie 20120501
Cadmium-mediated toxicity of lung epithelia is enhanced through NF-κB-mediated transcriptional activation of the human zinc transporter ZIP8. American journal of physiology. Lung cellular and molecular physiology 20120501
Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation. Free radical biology & medicine 20120501
IL-33 is induced by amyloid-β stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells. Inflammation 20120401
Inhibitory effects of melatonin on the lipopolysaccharide-induced CC chemokine expression in BV2 murine microglial cells are mediated by suppression of Akt-induced NF-κB and STAT/GAS activity. Journal of pineal research 20120401
Transglutaminase 2 expression is enhanced synergistically by interferon-γ and tumour necrosis factor-α in human small intestine. Clinical and experimental immunology 20120401
Direct regulation of interleukin-6 expression by Notch signaling in macrophages. Cellular & molecular immunology 20120301
Nicotine stimulates urokinase-type plasminogen activator receptor expression and cell invasiveness through mitogen-activated protein kinase and reactive oxygen species signaling in ECV304 endothelial cells. Toxicology and applied pharmacology 20120301
An NF-κB-independent and Erk1/2-dependent mechanism controls CXCL8/IL-8 responses of airway epithelial cells to cadmium. Toxicological sciences : an official journal of the Society of Toxicology 20120201
Interleukin-18 facilitates neutrophil transmigration via myosin light chain kinase-dependent disruption of occludin, without altering epithelial permeability. American journal of physiology. Gastrointestinal and liver physiology 20120201
Curcumin regulates airway epithelial cell cytokine responses to the pollutant cadmium. Biochemical and biophysical research communications 20120106
Involvement of JNK and NF-κB pathways in lipopolysaccharide (LPS)-induced BAG3 expression in human monocytic cells. Experimental cell research 20120101
Transcription of promoter from the human APRIL gene regulated by Sp1 and NF-kB. Neoplasma 20120101
Nuclear factor-kappa B inhibition can enhance apoptosis of differentiated thyroid cancer cells induced by 131I. PloS one 20120101
Alpha-tocopherol and BAY 11-7082 reduce vascular cell adhesion molecule in human aortic endothelial cells. Journal of vascular research 20120101
BAY 11-7082 is a broad-spectrum inhibitor with anti-inflammatory activity against multiple targets. Mediators of inflammation 20120101
STAT1 mediates oroxylin a inhibition of iNOS and pro-inflammatory cytokines expression in microglial BV-2 cells. PloS one 20120101
Microarray-assisted pathway analysis identifies MT1X & NFκB as mediators of TCRP1-associated resistance to cisplatin in oral squamous cell carcinoma. PloS one 20120101
Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells. Biochemical and biophysical research communications 20111202
Activation of the IκB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Tax-induced polyubiquitination. Journal of biochemistry 20111201
RNA released from necrotic keratinocytes upregulates intercellular adhesion molecule-1 expression in melanocytes. Archives of dermatological research 20111201
Dienogest inhibits Toll-like receptor 4 expression induced by costimulation of lipopolysaccharide and high-mobility group box 1 in endometrial epithelial cells. Fertility and sterility 20111201
Sodium dl-α-tocopheryl-6-O-phosphate inhibits PGE₂ production in keratinocytes induced by UVB, IL-1β and peroxidants. Bioorganic & medicinal chemistry 20111101
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. Nature biotechnology 20111101
Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivo. Antiviral research 20111001
Involvement of endoplasmic reticulum stress-mediated CHOP (GADD153) induction in the cytotoxicity of 2-aminophenoxazine-3-one in cancer cells. International journal of oncology 20111001
NF-κB induces abnormal centrosome amplification by upregulation of CDK2 in laryngeal squamous cell cancer. International journal of oncology 20111001
Effect of interleukin-17 on the expression of chemokines in gingival epithelial cells. European journal of oral sciences 20111001
Doxycycline up-regulates the expression of IL-6 and GM-CSF via MAPK/ERK and NF-κB pathways in mouse thymic epithelial cells. International immunopharmacology 20110901
An IκBα phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)-Nrf2-ARE signaling and ROS-PI3K/Akt signaling in an NF-κB-independent mechanism. Cellular signalling 20110901
Enhancement of toll-like receptor 2-mediated immune responses by AIMP1, a novel cytokine, in mouse dendritic cells. Immunology 20110901
Tumor necrosis factor-α induces epithelial-mesenchymal transition of renal cell carcinoma cells via a nuclear factor kappa B-independent mechanism. Experimental biology and medicine (Maywood, N.J.) 20110901
Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways. The Journal of surgical research 20110801
Nuclear factor-kappa B mediates TRPV4-NO pathway involved in thermal hyperalgesia following chronic compression of the dorsal root ganglion in rats. Behavioural brain research 20110801
Inhibition of nuclear factor-kappa B sensitises anterior pituitary cells to tumour necrosis factor-α- and lipopolysaccharide-induced apoptosis. Journal of neuroendocrinology 20110801
Up-regulation of breast cancer resistance protein plays a role in HER2-mediated chemoresistance through PI3K/Akt and nuclear factor-kappa B signaling pathways in MCF7 breast cancer cells. Acta biochimica et biophysica Sinica 20110801
Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma. Cancer discovery 20110801
NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells. British journal of cancer 20110712
5-aminolevulinic acid induce apoptosis via NF-κB/JNK pathway in human oral cancer Ca9-22 cells. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20110701
Combined effects of TNF-α, IL-1β, and HIF-1α on MMP-2 production in ACL fibroblasts under mechanical stretch: an in vitro study. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20110701
The biological and clinical impact of inhibition of NF-κB-initiated apoptosis in diffuse large B cell lymphoma (DLBCL). The Journal of pathology 20110701
[Plasmacytoid dendritic cells as therapeutic targets in novel therapeutics for autoimmune diseases]. [Rinsho ketsueki] The Japanese journal of clinical hematology 20110701
Divalent lead cations induce cyclooxygenase-2 gene expression by epidermal growth factor receptor/nuclear factor-kappa B signaling in A431carcinoma cells. Toxicology letters 20110610
TGF-β1 promoted MMP-2 mediated wound healing of anterior cruciate ligament fibroblasts through NF-κB. Connective tissue research 20110601
Kinase inhibitors modulate huntingtin cell localization and toxicity. Nature chemical biology 20110529
[Promotion effect of nuclear factor kappa B p65 on early fracture healing of rat radius by elevating prostaglandins E2 production and regulating inhibitor of DNA binding 2 protein expression]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20110501
Fenofibrate suppresses microvascular inflammation and apoptosis through adenosine monophosphate-activated protein kinase activation. Metabolism: clinical and experimental 20110401
Role of inflammation and insulin resistance in endothelial progenitor cell dysfunction. Diabetes 20110401
Quercetin and its principal metabolites, but not myricetin, oppose lipopolysaccharide-induced hyporesponsiveness of the porcine isolated coronary artery. British journal of pharmacology 20110401
Influence of nuclear factor-κB inhibition on endothelin-1 induced lung edema and oxidative stress in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110401
Aquaporin-4 expression in cultured astrocytes after fluid percussion injury. Journal of neurotrauma 20110301
The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis. Biochemical and biophysical research communications 20110218
Opioid-induced chemokine expression requires NF-κB activity: the role of PKCζ. Journal of leukocyte biology 20110201
NFκB inhibitors induce cell death in glioblastomas. Biochemical pharmacology 20110201
RNA-binding protein AUF1 regulates lipopolysaccharide-induced IL10 expression by activating IkappaB kinase complex in monocytes. Molecular and cellular biology 20110201
Requirement of the NF-κB pathway for induction of Wnt-5A by interleukin-1β in condylar chondrocytes of the temporomandibular joint: functional crosstalk between the Wnt-5A and NF-κB signaling pathways. Osteoarthritis and cartilage 20110101
The NFĸB pathway inhibitors Bay 11-7082 and parthenolide induce programmed cell death in anucleated Erythrocytes. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Tumor necrosis factor-alpha-nuclear factor-kappa B-signaling enhances St2b2 expression during 12-O-tetradecanoylphorbol-13-acetate-induced epidermal hyperplasia. Biological & pharmaceutical bulletin 20110101
Possible role of NF-ĸB signals in heat stress-associated increase in protein content of cultured C2C12 cells. Cells, tissues, organs 20110101
Emodin potentiates the antitumor effects of gemcitabine in pancreatic cancer cells via inhibition of nuclear factor-κB. Molecular medicine reports 20110101
IκB kinases increase Myc protein stability and enhance progression of breast cancer cells. Molecular cancer 20110101
ER stress drives Lipocalin 2 upregulation in prostate cancer cells in an NF-κB-dependent manner. BMC cancer 20110101
Hypoxia induces cysteine-rich 61, vascular endothelial growth factor, and interleukin-8 expressions in human nasal polyp fibroblasts: An implication of neutrophils in the pathogenesis of nasal polyposis. American journal of rhinology & allergy 20110101
Transcriptional activation of TINF2, a gene encoding the telomere-associated protein TIN2, by Sp1 and NF-κB factors. PloS one 20110101
Anticancer effects of 15d-prostaglandin-J2 in wild-type and doxorubicin-resistant ovarian cancer cells: novel actions on SIRT1 and HDAC. PloS one 20110101
Characterisation and manipulation of docetaxel resistant prostate cancer cell lines. Molecular cancer 20110101
Down-regulation of EBV-LMP1 radio-sensitizes nasal pharyngeal carcinoma cells via NF-κB regulated ATM expression. PloS one 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Abrogation of NF-κB signaling in human neutrophils induces neutrophil survival through sustained p38-MAPK activation. Journal of leukocyte biology 20101001
Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkappaBalpha phosphorylation in THP-1 cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100901
Oxidative stress enhances IL-8 and inhibits CCL20 production from intestinal epithelial cells in response to bacterial flagellin. American journal of physiology. Gastrointestinal and liver physiology 20100901
Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60. Frontiers of medicine in China 20100901
Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipopolysaccharide-stimulated NF-kappaB p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic E11 cells. Rheumatology (Oxford, England) 20100801
Chlamydial infection of monocytes stimulates IL-1beta secretion through activation of the NLRP3 inflammasome. Microbes and infection 20100801
Growth-stimulatory effect of resveratrol in human cancer cells. Molecular carcinogenesis 20100801
Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-{kappa}B activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKK{beta} as a potential target. Carcinogenesis 20100801
Co-regulation of nuclear respiratory factor-1 by NFkappaB and CREB links LPS-induced inflammation to mitochondrial biogenesis. Journal of cell science 20100801
Lipopolysaccharide induces calcitonin gene-related peptide in the RAW264.7 macrophage cell line. Immunology 20100701
mot-2-Mediated cross talk between nuclear factor-B and p53 is involved in arsenite-induced tumorigenesis of human embryo lung fibroblast cells. Environmental health perspectives 20100701
The repressive effect of NF-kappaB on p53 by mot-2 is involved in human keratinocyte transformation induced by low levels of arsenite. Toxicological sciences : an official journal of the Society of Toxicology 20100701
SIGNR1 ligation on murine peritoneal macrophages induces IL-12 production through NFkappaB activation. Glycoconjugate journal 20100701
A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens. Journal of immunological methods 20100630
TRAIL upregulates decoy receptor 1 and mediates resistance to apoptosis in insulin-secreting INS-1 cells. Biochemical and biophysical research communications 20100604
[Visfatin upregulates MMP-2 and MMP-9 expressions in human monocytes through activating NF-kappaB]. Zhonghua xin xue guan bing za zhi 20100501
Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model. Toxicology in vitro : an international journal published in association with BIBRA 20100401
NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction. Cancer research 20100401
Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome. The Journal of biological chemistry 20100326
Influence of NFkappaB inhibitors on IL-1beta-induced chemokine CXCL8 and -10 expression levels in intestinal epithelial cell lines: glucocorticoid ineffectiveness and paradoxical effect of PDTC. International journal of colorectal disease 20100301
Characterization of the 5'-flanking region and regulation of transcription of human BAFF-R gene. DNA and cell biology 20100301
Platelets and megakaryocytes contain functional nuclear factor-kappaB. Arteriosclerosis, thrombosis, and vascular biology 20100301
Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line. Cancer science 20100301
The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation. Cancer letters 20100227
A noble function of BAY 11-7082: Inhibition of platelet aggregation mediated by an elevated cAMP-induced VASP, and decreased ERK2/JNK1 phosphorylations. European journal of pharmacology 20100210
Rg1 protects the MPP+-treated MES23.5 cells via attenuating DMT1 up-regulation and cellular iron uptake. Neuropharmacology 20100201
IKK inhibitor bay 11-7082 induces necroptotic cell death in precursor-B acute lymphoblastic leukaemic blasts. British journal of haematology 20100201
[Effects of the inhibitor of NF-kappaB and IFN-gamma on BAFF-R gene promoter activity]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20100201
Inhibitor of IkappaB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells. Arthritis research & therapy 20100101
Inhibition of nuclear factor-kappa B differentially affects thyroid cancer cell growth, apoptosis, and invasion. Molecular cancer 20100101
BAY 11-7082, a nuclear factor-κB inhibitor, reduces inflammation and apoptosis in a rat cardiac ischemia-reperfusion injury model. International heart journal 20100101
Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. Acta poloniae pharmaceutica 20100101
MKP1 repression is required for the chemosensitizing effects of NF-kappaB and PI3K inhibitors to cisplatin in non-small cell lung cancer. Cancer letters 20091228
Tumor necrosis factor alpha represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of Smads through the activation of NF-kappaB. The Journal of biological chemistry 20091218
Upregulation of neutrophil gelatinase-associated lipocalin by ErbB2 through nuclear factor-kappaB activation. Cancer research 20091215
Inhibition of constitutive and cxc-chemokine-induced NF-kappaB activity potentiates ansamycin-based HSP90-inhibitor cytotoxicity in castrate-resistant prostate cancer cells. British journal of cancer 20091103
Cholesterol-3-beta, 5-alpha, 6-beta-triol induced PI(3)K-Akt-eNOS-dependent cyclooxygenase-2 expression in endothelial cells. Toxicology letters 20091028
N(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1. The Journal of biological chemistry 20091009
Extracellular redox modulation by regulatory T cells. Nature chemical biology 20091001
Arecoline-stimulated connective tissue growth factor production in human buccal mucosal fibroblasts: Modulation by curcumin. Oral oncology 20090901
Role of the phosphatidylinositol 3-kinase/protein kinase B pathway in regulating alternative splicing of tissue factor mRNA in human endothelial cells. Circulation journal : official journal of the Japanese Circulation Society 20090901
Targeting NF-kappaB signaling pathway suppresses tumor growth, angiogenesis, and metastasis of human esophageal cancer. Molecular cancer therapeutics 20090901
Porphyromonas gingivalis fimbriae-dependent interleukin-6 autocrine regulation by increase of gp130 in endothelial cells. Journal of periodontal research 20090801
An unbiased chemical biology screen identifies agents that modulate uptake of oxidized LDL by macrophages. Circulation research 20090717
Upregulation of proinflammatory cytokines and NO production in BV-activated avian macrophage-like cell line (HD11) requires MAPK and NF-kappaB pathways. International immunopharmacology 20090701
Novel cytostatic activity of the trypanocidal drug Benznidazole. International immunopharmacology 20090601
Low concentration of lipopolysaccharide acts on MC3T3-E1 osteoblasts and induces proliferation via the COX-2-independent NFkappaB pathway. Cell biochemistry and function 20090601
Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells. Toxicology and applied pharmacology 20090515
Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas. Journal of the National Cancer Institute 20090506
Imatinib resistance in multidrug-resistant K562 human leukemic cells. Leukemia research 20090501
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. Molecular endocrinology (Baltimore, Md.) 20090501
B-Lymphocyte stimulator: a new biomarker for multiple myeloma. European journal of haematology 20090401
Proteasome inhibition induces apoptosis in primary human natural killer cells and suppresses NKp46-mediated cytotoxicity. Haematologica 20090401
Antigen-specific suppression of inflammatory arthritis using liposomes. Journal of immunology (Baltimore, Md. : 1950) 20090315
Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation. Bioorganic & medicinal chemistry letters 20090215
Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis. Experimental cell research 20090201
EFEMP1 expression promotes in vivo tumor growth in human pancreatic adenocarcinoma. Molecular cancer research : MCR 20090201
The IKK-neutralizing compound Bay11 kills supereffector CD8 T cells by altering caspase-dependent activation-induced cell death. Journal of leukocyte biology 20090101
Adiponectin upregulates ferritin heavy chain in skeletal muscle cells. Diabetes 20090101
Insulin-like growth factor-1 promotes cell cycle progression via upregulation of cyclin D1 expression through the phosphatidylinositol 3-kinase/nuclear factor-kappaB signaling pathway in FRTL thyroid cells. Acta pharmacologica Sinica 20090101
Chemosensitization in non-small cell lung cancer cells by IKK inhibitor occurs via NF-kappaB and mitochondrial cytochrome c cascade. Journal of cellular and molecular medicine 20090101
The pivotal role of p38 and NF-kappaB signal pathways in the maturation of human monocyte-derived dendritic cells stimulated by streptococcal agent OK-432. Immunobiology 20090101
Mechanistic study on growth suppression and apoptosis induction by targeting hepatoma-derived growth factor in human hepatocellular carcinoma HepG2 cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20090101
Triglycerides potentiate the inflammatory response in rat Kupffer cells. Antioxidants & redox signaling 20081201
TNF-alpha-mediates neuroprotection against glutamate-induced excitotoxicity via NF-kappaB-dependent up-regulation of K2.2 channels. Journal of neurochemistry 20081101
Glucocorticoid-induced TNF receptor expression by T cells is reciprocally regulated by NF-kappaB and NFAT. Journal of immunology (Baltimore, Md. : 1950) 20081015
A nuclear factor-kappaB inhibitor BAY11-7082 inhibits interactions between human endothelial cells, T cells, and monocytes. Transplantation proceedings 20081001
BAY 11-7082 induces cell death through NF-kappaB-independent mechanisms in the Ewing's sarcoma family of tumours. Cancer letters 20080918
A role for the aryl hydrocarbon receptor and the dioxin TCDD in rheumatoid arthritis. Rheumatology (Oxford, England) 20080901
Innate immune responses of epididymal epithelial cells to Staphylococcus aureus infection. Immunology letters 20080815
Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells. Toxicological sciences : an official journal of the Society of Toxicology 20080801
Interleukin-1beta, but not interleukin-6, enhances renal and systemic endothelin production in vivo. American journal of physiology. Renal physiology 20080801
NF-kappaB inhibitors induce lytic cytotoxicity in Epstein-Barr virus-positive nasopharyngeal carcinoma cells. Cell biology international 20080801
Nrf2 regulates curcumin-induced aldose reductase expression indirectly via nuclear factor-kappaB. Pharmacological research 20080701
Death receptor-4 (DR4) expression is regulated by transcription factor NF-kappaB in response to etoposide treatment. Apoptosis : an international journal on programmed cell death 20080601
Development of a cell death-based method for the screening of nuclear factor-kappaB inhibitors. Journal of immunological methods 20080601
Adiponectin induces NF-kappaB activation that leads to suppression of cytokine-induced NF-kappaB activation in vascular endothelial cells: globular adiponectin vs. high molecular weight adiponectin. Diabetes & vascular disease research 20080601
Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells. Toxicology and applied pharmacology 20080415
Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. Cancer research 20080415
1-Bromopropane induces macrophage activation via extracellular signal-regulated kinase 1/2 MAPK and NF-κB pathways. Cancer letters 20080408
Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation. Journal of immunology (Baltimore, Md. : 1950) 20080401
Mitochondrial function and nuclear factor-kappaB-mediated signaling in radiation-induced bystander effects. Cancer research 20080401
Acetylcholine mediates the release of IL-8 in human bronchial epithelial cells by a NFkB/ERK-dependent mechanism. European journal of pharmacology 20080317
Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression. Experimental cell research 20080310
Decreased epithelial barrier function evoked by exposure to metabolic stress and nonpathogenic E. coli is enhanced by TNF-alpha. American journal of physiology. Gastrointestinal and liver physiology 20080301
The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes. Atherosclerosis 20080201
Mycobacterium bovis bacillus Calmette-Guerin induces CCL5 secretion via the Toll-like receptor 2-NF-kappaB and -Jun N-terminal kinase signaling pathways. Clinical and vaccine immunology : CVI 20080201
TNF alpha acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-kappa B-dependent pathways. Experimental cell research 20080201
Interferon-alpha induces transient upregulation of c-FLIP through NF-kappaB activation. Experimental cell research 20080115
Proinflammatory impact of Staphylococcus epidermidis on the nasal epithelium quantified by IL-8 and GRO-alpha responses in primary human nasal epithelial cells. International archives of allergy and immunology 20080101
Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation. Bioorganic & medicinal chemistry letters 20080101
Inhibition of NF-kappaB by (E)3-[(4-methylphenyl)-sulfonyl]-2-propenenitrile (BAY11-7082; BAY) is associated with enhanced 12-O-tetradecanoylphorbol-13-acetate-induced growth suppression and apoptosis in human prostate cancer PC-3 cells. International journal of oncology 20080101
Suppressive effect of hydroquinone, a benzene metabolite, on in vitro inflammatory responses mediated by macrophages, monocytes, and lymphocytes. Mediators of inflammation 20080101
[Cross-talk between nuclear factor-kappaB and P53 signal pathway in keratinocytes after ultraviolet B irradiation]. Zhonghua yi xue za zhi 20071120
Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis. Journal of leukocyte biology 20071001
Bortezomib inhibits nuclear factor-kappaB dependent survival and has potent in vivo activity in mesothelioma. Clinical cancer research : an official journal of the American Association for Cancer Research 20071001
[Enhancement of Fas-mediated apoptosis in leukemic cell line HL-60 by Bay 11 - 7082]. Zhongguo shi yan xue ye xue za zhi 20071001
Inhibition of NF-kappa B during human dendritic cell differentiation generates anergy and regulatory T-cell activity for one but not two human leukocyte antigen DR mismatches. Human immunology 20070901
Modulation of tight junction barrier function by outer membrane proteins of enteropathogenic Escherichia coli: role of F-actin and junctional adhesion molecule-1. Cell biology international 20070801
High-content classification of nucleocytoplasmic import or export inhibitors. Journal of biomolecular screening 20070801
Effect of ionizing radiation on cellular procoagulability and co-ordinated gene alterations. Haematologica 20070801
Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-kappaB. Arthritis and rheumatism 20070701
Curcumin attenuates inflammatory responses of TNF-alpha-stimulated human endothelial cells. Journal of cardiovascular pharmacology 20070701
NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia. Oncogene 20070614
Hydrogen sulfide induces the synthesis of proinflammatory cytokines in human monocyte cell line U937 via the ERK-NF-kappaB pathway. Journal of leukocyte biology 20070501
Influence of the fungal NF-kappaB inhibitor panepoxydone on inflammatory gene expression in MonoMac6 cells. International immunopharmacology 20070501
Advanced glycation endproducts mediate pro-inflammatory actions in human gestational tissues via nuclear factor-kappaB and extracellular signal-regulated kinase 1/2. The Journal of endocrinology 20070501
Inflammatory effect of endosulfan via NF-kappaB activation in macrophages. Biochemical and biophysical research communications 20070420
Helicobacter pylori stimulates urokinase plasminogen activator receptor expression and cell invasiveness through reactive oxygen species and NF-kappaB signaling in human gastric carcinoma cells. International journal of molecular medicine 20070401
Activation of transcription factor IL-6 (NF-IL-6) and nuclear factor-kappaB (NF-kappaB) by lipid ozonation products is crucial to interleukin-8 gene expression in human airway epithelial cells. Environmental toxicology 20070401
The proteasome inhibitor bortezomib acts independently of p53 and induces cell death via apoptosis and mitotic catastrophe in B-cell lymphoma cell lines. Cancer research 20070315
Involvement of nuclear factor-kB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells. Molecular human reproduction 20070301
Anti-inflammatory effects of the advanced glycation end product inhibitor LR-90 in human monocytes. Diabetes 20070301
Pharmacological inhibitors of NF-kappaB accelerate apoptosis in chronic lymphocytic leukaemia cells. Oncogene 20070222
Differential involvement of NF-kappaB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils. Journal of leukocyte biology 20070201
Ceramide induces early and late apoptosis in human papilloma virus+ cervical cancer cells by inhibiting reactive oxygen species decay, diminishing the intracellular concentration of glutathione and increasing nuclear factor-kappaB translocation. Anti-cancer drugs 20070201
NF-kappa B as a target for cancer therapy. Expert opinion on therapeutic targets 20070201
Inhibition of human preadipocyte proteasomal activity by HIV protease inhibitors or specific inhibitor lactacystin leads to a defect in adipogenesis, which involves matrix metalloproteinase-9. The Journal of pharmacology and experimental therapeutics 20070101
Gene expression profiling of LPS-stimulated murine macrophages and role of the NF-kappaB and PI3K/mTOR signaling pathways. Annals of the New York Academy of Sciences 20070101
Hydrogen peroxide increases [3H]-2-deoxyglucose uptake via MAPKs, cPLA2, and NF-kappaB signaling pathways in mouse embryonic stem cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101
Epidermal growth factor inhibits Fas-mediated apoptosis in salivary epithelial cells of patients with primary Sjögren's syndrome. Clinical and experimental rheumatology 20070101
NF-kB inhibition as a strategy to enhance etoposide-induced apoptosis in K562 cell line. American journal of hematology 20061201
Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis. Biochemical pharmacology 20061130
Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells. American journal of physiology. Gastrointestinal and liver physiology 20061101
Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells. The Journal of pharmacology and experimental therapeutics 20061101
Bortezomib induces different apoptotic rates in B-CLL cells according to IgVH and BCL-6 mutations. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061101
Resistin worsens cardiac ischaemia-reperfusion injury. Biochemical and biophysical research communications 20061013
Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: the type of DNA damage determines the final outcome. Oncogene 20061012
COX-2 is associated with cadmium-induced ICAM-1 expression in cerebrovascular endothelial cells. Toxicology letters 20060910
Raloxifene increases proliferation and up-regulates telomerase activity in human umbilical vein endothelial cells. The Journal of biological chemistry 20060825
House dust mite allergen Der p 1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells. International immunology 20060801
TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. Proceedings of the National Academy of Sciences of the United States of America 20060705
Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity. Carcinogenesis 20060701
Serum amyloid A induces contrary immune responses via formyl peptide receptor-like 1 in human monocytes. Molecular pharmacology 20060701
An osteopontin-NADPH oxidase signaling cascade promotes pro-matrix metalloproteinase 9 activation in aortic mesenchymal cells. Circulation research 20060623
Infectious bursal disease virus infection induces macrophage activation via p38 MAPK and NF-kappaB pathways. Virus research 20060601
Proinsulin C-peptide stimulates a PKC/IkappaB/NF-kappaB signaling pathway to activate COX-2 gene transcription in Swiss 3T3 fibroblasts. Journal of biochemistry 20060601
Nuclear Factor-kappaB controls the reaggregation of 3D neurosphere cultures in vitro. European cells & materials 20060523
Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regulatory peptides 20060515
Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways. Liver international : official journal of the International Association for the Study of the Liver 20060501
NF-kappaB is essential for the progression of KSHV- and EBV-infected lymphomas in vivo. Blood 20060415
Shortcomings of protein removal prior to high performance liquid chromatographic analysis-A case study using method development for BAY 11-7082. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060413
Stereospecific and redox-sensitive increase in monocyte adhesion to endothelial cells by homocysteine. Arteriosclerosis, thrombosis, and vascular biology 20060301
Lipopolysaccharide and TNF-alpha activate the nuclear factor kappa B pathway in the human placental JEG-3 cells. Placenta 20060101
Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through nuclear factor-kappaB-related survival pathway down-regulation. The Journal of pharmacology and experimental therapeutics 20060101
The novel cytokine p43 induces IL-12 production in macrophages via NF-kappaB activation, leading to enhanced IFN-gamma production in CD4+ T cells. Journal of immunology (Baltimore, Md. : 1950) 20060101
Inhibition of NF-kappaB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines. Leukemia research 20051201
Activity and function of the nuclear factor kappaB pathway in human parathyroid tumors. Endocrine-related cancer 20051201
The ACAT inhibitor VULM1457 significantly reduced production and secretion of adrenomedullin (AM) and down-regulated AM receptors on human hepatoblastic cells. General physiology and biophysics 20051201
Lipopolysaccharide rapidly modifies adenosine receptor transcripts in murine and human macrophages: role of NF-kappaB in A(2A) adenosine receptor induction. The Biochemical journal 20051101
Enhancement of TPA-induced growth inhibition and apoptosis in myeloid leukemia cells by BAY 11-7082, an NF-kappaB inhibitor. International journal of oncology 20051001
Effects of nuclear factor-kappaB inhibitors and its implication on natural killer T-cell lymphoma cells. British journal of haematology 20051001
S100b counteracts effects of the neurotoxicant trimethyltin on astrocytes and microglia. Journal of neuroscience research 20050901
NF-kappaB activation contributes to anthracycline resistance pathway in human ovarian carcinoma cell line A2780. International journal of oncology 20050901
Activation of NF-kappaB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells. The Journal of biological chemistry 20050826
Methoxychlor-induced inducible nitric oxide synthase and proinflammatory cytokines expression in macrophages via NF-kappaB, ERK, and p38 mitogen-activated protein kinases. Biochemical and biophysical research communications 20050812
Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-kappaB pathway. Cell death and differentiation 20050801
Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB. American journal of respiratory cell and molecular biology 20050801
Induction of interleukin-8 production via nuclear factor-kappaB activation in human intestinal epithelial cells infected with Vibrio vulnificus. Immunology 20050801
Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation. Molecular and cellular biology 20050701
Enhancing the ratio of molecular ions to non-covalent compounds in the electrospray interface of LC-MS in quantitative analysis. Analytical and bioanalytical chemistry 20050601
Effects of mechanistically distinct NF-kappaB inhibitors on glial inducible nitric-oxide synthase expression. Nitric oxide : biology and chemistry 20050601
Juzentaihoto, a Kampo medicine, enhances IL-12 production by modulating Toll-like receptor 4 signaling pathways in murine peritoneal exudate macrophages. International immunopharmacology 20050501
Potential mechanism of blood vessel protection by resveratrol, a component of red wine. Annals of the New York Academy of Sciences 20050501
Diesel exhaust particles induce the over expression of tumor necrosis factor-alpha (TNF-alpha) gene in alveolar macrophages and failed to induce apoptosis through activation of nuclear factor-kappaB (NF-kappaB). International journal of environmental research and public health 20050501
The inhibitor of I kappa B alpha phosphorylation BAY 11-7082 prevents NMDA neurotoxicity in mouse hippocampal slices. Neuroscience letters 20050404
Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and I kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro. Endocrinology 20050301
Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells. Biochemical pharmacology 20050101
Role of p38 MAPK and NF-kB for chemokine release in coculture of human eosinophils and bronchial epithelial cells. Clinical and experimental immunology 20050101
Interferon-gamma-dependent in vitro model for the putative keratin 17 autoimmune loop in psoriasis: exploration of pharmaco- and gene-therapeutic effects. Skin pharmacology and physiology 20050101
Inhibition of IkappaBalpha phosphorylation prevents glutamate-induced NF-kappaB activation and neuronal cell death. Acta neurochirurgica. Supplement 20050101
Lysophospholipids increase ICAM-1 expression in HUVEC through a Gi- and NF-kappaB-dependent mechanism. American journal of physiology. Cell physiology 20041201
Mechanisms for macrophage-mediated HIV-1 induction. Journal of immunology (Baltimore, Md. : 1950) 20041201
Enteropathogenic Escherichia coli outer membrane proteins induce iNOS by activation of NF-kappaB and MAP kinases. Inflammation 20041201
Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase. The Journal of biological chemistry 20041105
Nuclear factor kappaB activity determines the sensitivity of kidney epithelial cells to apoptosis: implications for mercury-induced renal failure. Toxicological sciences : an official journal of the Society of Toxicology 20041101
[BAY11-7082 and Lactacystein in CD154-induced NF-kappaB activation]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20041001
Induction of endothelial iNOS by 4-hydroxyhexenal through NF-kappaB activation. Free radical biology & medicine 20040815
In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse. Journal of immunology (Baltimore, Md. : 1950) 20040801
T cells signaled by NF-kappa B- dendritic cells are sensitized not anergic to subsequent activation. Journal of immunology (Baltimore, Md. : 1950) 20040801
Angiotensin II stimulates the release of interleukin-6 and interleukin-8 from cultured human adipocytes by activation of NF-kappaB. Arteriosclerosis, thrombosis, and vascular biology 20040701
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity. Diabetologia 20040501
Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact. American journal of respiratory cell and molecular biology 20040401
Interruption of the NF-kappaB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells. Blood 20040401
Id-1 expression induces androgen-independent prostate cancer cell growth through activation of epidermal growth factor receptor (EGF-R). Carcinogenesis 20040401
Regulation of glutathione S-transferase P1-1 gene expression by NF-kappaB in tumor necrosis factor alpha-treated K562 leukemia cells. Biochemical pharmacology 20040401
Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells. Journal of virology 20040401
Ethanol-induced iNOS and COX-2 expression in cultured astrocytes via NF-kappa B. Neuroreport 20040322
The molecular mechanism of sensitization to Fas-mediated apoptosis by 2-methoxyestradiol in PC3 prostate cancer cells. Molecular carcinogenesis 20040101
Induction of intercellular adhesion molecule-1 on human brain endothelial cells by HIV-1 gp120: role of CD4 and chemokine coreceptors. Laboratory investigation; a journal of technical methods and pathology 20031201
The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571. Blood 20031115
Pharmacological analysis of signal transduction pathways required for oxidative burst in chicken heterophils stimulated by a Toll-like receptor 2 agonist. International immunopharmacology 20031101
Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors. Free radical biology & medicine 20031101
Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. Journal of immunology (Baltimore, Md. : 1950) 20030701
Mechanisms of endotoxin tolerance in human intestinal microvascular endothelial cells. Journal of immunology (Baltimore, Md. : 1950) 20030615
Upregulation of expression of the chemokine receptor CCR5 by hydrogen peroxide in human monocytes. Mediators of inflammation 20030201
Characterization of the molecular events following impairment of NF-kappaB-driven transcription in neurons. Brain research. Molecular brain research 20021230
Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis. Cancer research 20021201
Contributions of mitogen-activated protein kinase and nuclear factor kappa B to N-(4-hydroxyphenyl)retinamide-induced apoptosis in prostate cancer cells. Molecular carcinogenesis 20021101
Bay 11-7082 inhibits transcription factor NF-kappaB and induces apoptosis of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells. Blood 20020901
Expression of kinin B(1) receptor in fresh or cultured rabbit aortic smooth muscle: role of NF-kappa B. American journal of physiology. Heart and circulatory physiology 20020701
High glucose induced nuclear factor kappa B mediated inhibition of endothelial cell migration. Atherosclerosis 20020601
Further pharmacological evidence of nuclear factor-kappa B pathway involvement in bradykinin B1 receptor-sensitized responses in human umbilical vein. The Journal of pharmacology and experimental therapeutics 20020601
A nuclear factor-kappaB inhibitor BAY 11-7082 suppresses endothelin-1 production in cultured vascular endothelial cells. Japanese journal of pharmacology 20020501
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer. Oncogene 20011101
NF-kappa B-mediated chemoresistance in breast cancer cells. Surgery 20010801
CD40L induces matrix-metalloproteinase-9 but not tissue inhibitor of metalloproteinases-1 in cervical carcinoma cells: imbalance between NF-kappaB and STAT3 activation. Experimental cell research 20010715
Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis. The Journal of biological chemistry 20000121
Mechanism of PKA-dependent and lipid-raft independent stimulation of Connexin43 expression by oxytoxin in mouse embryonic stem cells. Molecular endocrinology (Baltimore, Md.)
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