Bisdemethoxycurcumin
Title | Journal |
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Curcuminoids distinctly exhibit antioxidant activities and regulate expression of scavenger receptors and heme oxygenase-1. | Molecular nutrition & food research 20130901 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | Bioorganic & medicinal chemistry 20121115 |
Curcumin is an inhibitor of calcium/calmodulin dependent protein kinase II. | Bioorganic & medicinal chemistry 20121015 |
Evaluation in vitro of synthetic curcumins as agents promoting monocytic gene expression related to β-amyloid clearance. | Chemical research in toxicology 20120113 |
Structural investigation into the inhibitory mechanisms of indomethacin and its analogues towards human glyoxalase I. | Bioorganic & medicinal chemistry letters 20110715 |
Significant enhancement in radical-scavenging activity of curcuminoids conferred by acetoxy substituent at the central methylene carbon. | Bioorganic & medicinal chemistry 20110615 |
Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies. | Bioorganic & medicinal chemistry 20110201 |
Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity. | European journal of medicinal chemistry 20101001 |
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. | Journal of natural products 20100723 |
Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species. | European journal of medicinal chemistry 20100301 |
Optimized turmeric extracts have potent anti-amyloidogenic effects. | Current Alzheimer research 20091201 |
Induction of antioxidant enzymes by curcumin and its analogues in human islets: implications in transplantation. | Pancreas 20090501 |
Comparative antiulcer effect of bisdemethoxycurcumin and curcumin in a gastric ulcer model system. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20090401 |
Structure-activity relationship studies of curcumin analogues. | Bioorganic & medicinal chemistry letters 20090401 |
Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA. | The Journal of nutritional biochemistry 20090201 |
Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease. | Pharmacology, biochemistry, and behavior 20090201 |
Curcumin is a potent DNA hypomethylation agent. | Bioorganic & medicinal chemistry letters 20090201 |
Comparison of inhibitory potency of three different curcuminoid pigments on nitric oxide and tumor necrosis factor production of rat primary microglia induced by lipopolysaccharide. | Neuroscience letters 20081205 |
Effect of pure curcumin, demethoxycurcumin, and bisdemethoxycurcumin on WT1 gene expression in leukemic cell lines. | Cancer chemotherapy and pharmacology 20080901 |
Dimethoxycurcumin, a synthetic curcumin analogue with higher metabolic stability, inhibits NO production, inducible NO synthase expression and NF-kappaB activation in RAW264.7 macrophages activated with LPS. | Molecular nutrition & food research 20080901 |
Synthesis and evaluation of curcumin analogues as potential thioredoxin reductase inhibitors. | Bioorganic & medicinal chemistry 20080901 |
Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators in vitro and in vivo. | Archives of pharmacal research 20080401 |
Immune defects in Alzheimer's disease: new medications development. | BMC neuroscience 20080101 |
Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells. | American journal of physiology. Endocrinology and metabolism 20070901 |
Curcuminoids purified from turmeric powder modulate the function of human multidrug resistance protein 1 (ABCC1). | Cancer chemotherapy and pharmacology 20060201 |
Efficiency of foam fractionation for the enrichment of nonpolar compounds from aqueous extracts of plant materials. | Journal of natural products 20050901 |
A labdane diterpene glucoside from the rhizomes of Curcuma mangga. | Journal of natural products 20050701 |
Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of alpha,beta-unsaturated carbonyl compounds. | Biochemical pharmacology 20050615 |
Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents. | Bioorganic & medicinal chemistry letters 20050401 |
Curcuminoids and sesquiterpenoids in turmeric (Curcuma longa L.) suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice. | Journal of agricultural and food chemistry 20050223 |
Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder. | Biochemical pharmacology 20041115 |
In vitro peroxynitrite scavenging activity of diarylheptanoids from Curcuma longa. | Phytotherapy research : PTR 20030501 |
Studies on the role of some synthetic curcuminoid derivatives in the inhibition of tumour specific angiogenesis. | Journal of experimental & clinical cancer research : CR 20030301 |
Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease. | Journal of natural products 20020901 |
CoMFA and CoMSIA 3D QSAR and docking studies on conformationally-restrained cinnamoyl HIV-1 integrase inhibitors: exploration of a binding mode at the active site. | Journal of medicinal chemistry 20020214 |
Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling. | Journal of medicinal chemistry 19981008 |
Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action. | Journal of medicinal chemistry 19970912 |