Home Other Building Blocks 2-Amino-2-(3-oxo-2,3-dihydroisoxazol-5-yl)acetic acid

2-Amino-2-(3-oxo-2,3-dihydroisoxazol-5-yl)acetic acid

CAS No.:
2552-55-8
Catalog Number:
AG003BE7
Molecular Formula:
C5H6N2O4
Molecular Weight:
158.1121
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$122
- +
5mg
98%
1 week
United States
$321
- +
10mg
98%
1 week
United States
$529
- +
25mg
98%
1 week
United States
$1085
- +
50mg
98%
1 week
United States
$1862
- +
Product Description
Catalog Number:
AG003BE7
Chemical Name:
2-Amino-2-(3-oxo-2,3-dihydroisoxazol-5-yl)acetic acid
CAS Number:
2552-55-8
Molecular Formula:
C5H6N2O4
Molecular Weight:
158.1121
MDL Number:
MFCD00069294
IUPAC Name:
2-amino-2-(3-oxo-1,2-oxazol-5-yl)acetic acid
InChI:
InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
InChI Key:
IRJCBFDCFXCWGO-UHFFFAOYSA-N
SMILES:
OC(=O)C(c1o[nH]c(=O)c1)N
NSC Number:
204850
Properties
Complexity:
235  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
158.033g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
158.113g/mol
Monoisotopic Mass:
158.033g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
102A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.9  
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Ibotenic acid lesions to ventrolateral thalamic nuclei disrupts trace and delay eyeblink conditioning in rabbits. Behavioural brain research 20070416
Attenuation of the blood flow response to physostigmine in the rat cortex deafferented from the basal forebrain. Brain research bulletin 20070402
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Tolerance of Drosophila flies to ibotenic acid poisons in mushrooms. Journal of chemical ecology 20070201
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The median preoptic nucleus is involved in the facilitation of heat-escape/cold-seeking behavior during systemic salt loading in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20070101
Heparan sulfate mediates neuroprotection from degeneration in experimental glutaric aciduria. Cell transplantation 20070101
Peroxiredoxins in the central nervous system. Sub-cellular biochemistry 20070101
Analysis of hallucinogenic constituents in Amanita mushrooms circulated in Japan. Forensic science international 20061220
Thiorphan, a neutral endopeptidase inhibitor used for diarrhoea, is neuroprotective in newborn mice. Brain : a journal of neurology 20061201
Unilateral ibotenic acid lesions of the prefrontal cortex reduce rotational behavior in 6-hydroxydopamine-lesioned rats. Acta medica Okayama 20061201
The role of CA3 and CA1 in the acquisition of an object-trace-place paired-associate task. Behavioral neuroscience 20061201
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Cognitive dysfunction induced by sequential injection of amyloid-beta and ibotenate into the bilateral hippocampus; protection by memantine and MK-801. European journal of pharmacology 20061024
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Treatment-induced prevention of learning deficits in newborn mice with brain lesions. Neuroscience 20060825
The expression of social dominance following neonatal lesions of the amygdala or hippocampus in rhesus monkeys (Macaca mulatta). Behavioral neuroscience 20060801
Neonatal lesions of the ventral hippocampus in rats lead to prefrontal cognitive deficits at two maturational stages. Neuroscience 20060707
Cerebral metabolic consequences in the adult brain after neonatal excitotoxic lesions of the amygdala in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060701
Effect of dopamine D3 antagonists on PPI in DBA/2J mice or PPI deficit induced by neonatal ventral hippocampal lesions in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060701
Evidence for disease-regulated transgene expression in the brain with use of lentiviral vectors. Journal of neuroscience research 20060701
Effects of Yukmijihwang-tang derivatives (YMJd) on ibotenic acid-induced amnesia in the rat. Biological & pharmaceutical bulletin 20060701
Disconnection analysis of CA3 and DG in mediating encoding but not retrieval in a spatial maze learning task. Learning & memory (Cold Spring Harbor, N.Y.) 20060701
Lesions of suprachiasmatic nucleus efferents selectively affect rest-activity rhythm. Molecular and cellular endocrinology 20060627
Endocannabinoids potently protect the newborn brain against AMPA-kainate receptor-mediated excitotoxic damage. British journal of pharmacology 20060601
The pedunculopontine tegmental nucleus and responding for sucrose reward. Behavioral neuroscience 20060601
Selective excitotoxic lesions of the hippocampus and basolateral amygdala have dissociable effects on appetitive cue and place conditioning based on path integration in a novel Y-maze procedure. The European journal of neuroscience 20060601
On the retention of neurotensin in the ventral tegmental area (VTA) despite destruction of the main neurotensinergic afferents of the VTA--implications for the organization of forebrain projections to the VTA. Brain research 20060504
Cortical intrinsic circuits can support activity propagation through an isofrequency strip of the guinea pig primary auditory cortex. Cerebral cortex (New York, N.Y. : 1991) 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Investigation of a route to ibotenic acid analogues via a reduced pyroglutamate template. Organic & biomolecular chemistry 20060421
Systemic application of granulocyte-colony stimulating factor and stem cell factor exacerbates excitotoxic brain injury in newborn mice. Pediatric research 20060401
Intravenous self-administration of nicotine is altered by lesions of the posterior, but not anterior, pedunculopontine tegmental nucleus. The European journal of neuroscience 20060401
Effects of lesions to the dorsal and ventral hippocampus on defensive behaviors in rats. The European journal of neuroscience 20060401
Investigating the effect of bilateral amygdala lesions on fear conditioning and social interaction in the male Mongolian gerbil. Brain research 20060317
Behavioural effects of neonatal lesions of the medial prefrontal cortex and subchronic pubertal treatment with phencyclidine of adult rats. Behavioural brain research 20060315
Ibotenic acid lesions of the medial preoptic area disrupt the expression of partner preference in sexually receptive female rats. Brain research 20060303
Effects of clozapine on memory function in the rat neonatal hippocampal lesion model of schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry 20060301
The role of the hippocampus in object recognition in rats: examination of the influence of task parameters and lesion size. Behavioural brain research 20060215
Do neonatal bilateral ibotenic acid lesions of the hippocampal formation or of the amygdala impair HPA axis responsiveness and regulation in infant rhesus macaques (Macaca mulatta)? Brain research 20060203
The effects of dexmedetomidine on perinatal excitotoxic brain injury are mediated by the alpha2A-adrenoceptor subtype. Anesthesia and analgesia 20060201
Medial parabrachial nucleus neurons modulate d-fenfluramine-induced anorexia through 5HT2C receptors. Brain research 20060105
Risperidone pretreatment prevents elevated locomotor activity following neonatal hippocampal lesions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060101
Regulatable acetylcholine-producing fibroblasts enhance cognitive performance. Molecular therapy : the journal of the American Society of Gene Therapy 20060101
Transient attenuation of neuropathic manifestations in rats following lesion or reversible block of the lateral thalamic somatosensory nuclei. Experimental neurology 20060101
Medial prefrontal cortex lesions inhibit reflex micturition in anethetized rats. Neuroscience research 20060101
The metabotropic glutamate receptor subtype 5 antagonist MPEP and the Na+ channel blocker riluzole show different neuroprotective profiles in reversing behavioral deficits induced by excitotoxic prefrontal cortex lesions. Neuroscience 20060101
Effects of hippocampal lesions on the monkey's ability to learn large sets of object-place associations. Hippocampus 20060101
Effects of partial hippocampal lesions by ibotenic acid on repeated acquisition of spatial discrimination in pigeons. Reviews in the neurosciences 20060101
Effects of hippocampal lesions on conditional discriminations in rats. Reviews in the neurosciences 20060101
[Neuroprotective effect of the hexapeptide HLDF-6 on neurons of rat hippocampus on the model of Alzheimer's disease in vivo and in vitro]. Bioorganicheskaia khimiia 20060101
Patterns of hippocampal cell loss based on subregional lesions of the hippocampus. Brain research 20051214
Topiramate prevents excitotoxic damage in the newborn rodent brain. Neurobiology of disease 20051201
Specific changes in conditioned responding following neurotoxic damage to the posterior parietal cortex. Behavioral neuroscience 20051201
Post insult enriched housing improves the 8-arm radial maze performance but not the Morris water maze task in ventral subicular lesioned rats. Brain research 20051130
Chronic excitotoxic lesion of the dorsal raphe nucleus induces sodium appetite. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20051101
Unilateral lesion of the pedunculopontine nucleus induces hyperactivity in the subthalamic nucleus and substantia nigra in the rat. The European journal of neuroscience 20051101
Opposing effects of amygdala and orbital prefrontal cortex lesions on the extinction of instrumental responding in macaque monkeys. The European journal of neuroscience 20051101
A new approach to the pharmacological regulation of memory: Sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models. Brain research 20051026
Neurochemical correlates of differential neuroprotection by long-term dietary creatine supplementation. Brain research 20051005
[Effects of ibotenic acid lesions to rat's hippocampus CA1 on place and cue learning in Morris water maze]. Shinrigaku kenkyu : The Japanese journal of psychology 20051001
Behavioral and morphological alterations following neonatal excitotoxic lesions of the medial prefrontal cortex in rats. Experimental neurology 20050901
VPAC2 receptors mediate vasoactive intestinal peptide-induced neuroprotection against neonatal excitotoxic brain lesions in mice. The Journal of pharmacology and experimental therapeutics 20050801
Neuronal markers expression of NGF-primed bone marrow cells (BMCs) transplanted in the brain of 6-hydroxydopamine and ibotenic acid lesioned littermate mice. Neuroscience letters 20050801
Excitotoxic lesions of the entorhinal cortex leave gustatory within-event learning intact. Behavioral neuroscience 20050801
Pontine-wave generator activation-dependent memory processing of avoidance learning involves the dorsal hippocampus in the rat. Journal of neuroscience research 20050601
The entorhinal cortex regulates blood glucose level in response to microinjection of neostigmine into the hippocampus. Neuro endocrinology letters 20050601
[Effects of the Panax notoginseng saponins on the level of synaptophysin protein in brain in rat model with lesion of Meynert]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601
Ibotenic acid lesions of the medial prefrontal cortex block the development and expression of 3,4-methylenedioxymethamphetamine-induced behavioral sensitization in rats. Behavioural brain research 20050528
Effects of pre-training pedunculopontine tegmental nucleus lesions on delayed matching- and non-matching-to-position in a T-maze in rats. Behavioural brain research 20050507
Natural reward-related learning in rats with neonatal ventral hippocampal lesions and prior cocaine exposure. Psychopharmacology 20050501
Glutamatergic chloride currents associated to glutamate transport? Neuroscience letters 20050404
Carotid body denervation alters ventilatory responses to ibotenic acid injections or focal acidosis in the medullary raphe. Journal of applied physiology (Bethesda, Md. : 1985) 20050401
Role of gustatory thalamus in anticipation and comparison of rewards over time in rats. American journal of physiology. Regulatory, integrative and comparative physiology 20050401
Effect of excitotoxic lesions of the neonatal ventral hippocampus on the immobility response in rats. Life sciences 20050401
Glial overexpression of heme oxygenase-1: a histochemical marker for early stages of striatal damage. Journal of chemical neuroanatomy 20050301
Experimental cortical dysplasia following ibotenate administration in hamsters: pathogenesis of microgyria and associated gray matter heterotopia. Congenital anomalies 20050301
Effect of acamprosate on neonatal excitotoxic cortical lesions in in utero alcohol-exposed hamsters. Neuroscience letters 20050210
Effect of perinatal alcohol exposure on ibotenic acid-induced excitotoxic cortical lesions in newborn hamsters. Pediatric research 20050201
Dipsogenic stimulation in ibotenic DRN-lesioned rats induces concomitant sodium appetite. Neuroscience letters 20050201
[Protective effects of Panax notoginseng saponins against pathological lesion of cholinergic neuron in rat model with Alzheimer' s disease]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050201
Effects of ibotenic acid lesions of the mediodorsal thalamus on memory: relationship with emotional processes in mice. Behavioural brain research 20050130
Spatial discrimination deficits by excitotoxic lesions in the Morris water escape task. Behavioural brain research 20050130
Neurochemical and behavioral effects of the intrahippocampal co-injection of beta-amyloid protein1-40 and ibotenic acid in rats. Life sciences 20050128
Selective neurotoxic damage to the hippocampal formation impairs performance of the transverse patterning and location memory tasks in rhesus macaques. Hippocampus 20050101
Ontogenic study of the influence of tissue plasminogen activator (t-PA) in neonatal excitotoxic brain insult and the subsequent microglia/macrophage activation. Neuroscience 20050101
Alterations in dendritic morphology of prefrontal cortical and nucleus accumbens neurons in post-pubertal rats after neonatal excitotoxic lesions of the ventral hippocampus. Neuroscience 20050101
4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes. Neuropharmacology 20050101
Differential effects of infralimbic cortical lesions on temperature and locomotor activity responses to feeding in rats. Neuroscience 20050101
Prolonged initiation latency in Morris water maze learning in rats with ibotenic acid lesions to medial striatum: effects of systemic and intranigral muscimol administration. Brain research 20041231
Perirhinal and postrhinal contributions to remote memory for context. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041208
Transient attenuation of CO2 sensitivity after neurotoxic lesions in the medullary raphe area of awake goats. Journal of applied physiology (Bethesda, Md. : 1985) 20041201
Behavioral and neurochemical effects of the intrahippocampal co-injection of beta-amyloid protein 1-40 and ibotenic acid in rats. The International journal of neuroscience 20041201
Effects of ventral hippocampal lesion on thermal and mechanical nociception in neonates and adult rats. The European journal of neuroscience 20041201
Large lesions in the pre-Bötzinger complex area eliminate eupneic respiratory rhythm in awake goats. Journal of applied physiology (Bethesda, Md. : 1985) 20041101
Effects of methanol extract of Uncariae Ramulus et Uncus on ibotenic acid-induced amnesia in the rat. Journal of pharmacological sciences 20041101
Neurotoxic lesions of phasic pontine-wave generator cells impair retention of 2-way active avoidance memory. Sleep 20041101
Spatial conditional associative learning: effects of thalamo-hippocampal disconnection in rats. Neuroreport 20041025
Hypothalamic paraventricular nucleus neurons regulate medullary catecholamine cell responses to restraint stress. The Journal of comparative neurology 20041004
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. European journal of pharmacology 20040919
Cerebrovasodilation evoked by stimulation of subthalamic vasodilator area and hypoxia depends upon the integrity of cortical neurons in the rat. Neuroscience letters 20040916
KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Selective neurotoxic lesions of basolateral and central nuclei of the amygdala produce differential effects on fear conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040901
Mutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues. The Journal of biological chemistry 20040813
Age-dependent effect of cholinergic lesion on dendritic morphology in rat frontal cortex. Neurobiology of aging 20040801
Contribution of the medial amygdaloid nucleus to the development of hypertension in spontaneously hypertensive rats. Neuroscience letters 20040722
A critical role for the parabrachial nucleus in generating central nervous system responses elicited by a systemic immune challenge. Journal of neuroimmunology 20040701
Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040630
One-trial odor-reward association: a form of event memory not dependent on hippocampal function. Behavioral neuroscience 20040601
Is the songbird Area X striatal, pallidal, or both? An anatomical study. The Journal of comparative neurology 20040531
Effects of ibotenate pedunculopontine tegmental nucleus lesions on exploratory behaviour in the open field. Behavioural brain research 20040505
Effects of ibotenic acid lesions of the dorsal hippocampus on contextual fear conditioning in mice: comparison with mammillary body lesions. Behavioural brain research 20040505
Combined unilateral lesions of the amygdala and orbital prefrontal cortex impair affective processing in rhesus monkeys. Journal of neurophysiology 20040501
Hallucinogens and dissociative agents naturally growing in the United States. Pharmacology & therapeutics 20040501
Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid. European journal of pharmacology 20040319
Agonist enhacement of macrocyclic lactone activity at a glutamate-gated chloride channel subunit from Haemonchus contortus. Biochemical pharmacology 20040315
Ectopic parvalbumin expression in mouse forebrain neurons increases excitotoxic injury provoked by ibotenic acid injection into the striatum. Experimental neurology 20040301
The hippocampal/parahippocampal regions and recognition memory: insights from visual paired comparison versus object-delayed nonmatching in monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040225
Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors. European journal of pharmacology 20040223
Excitotoxic lesions of the prefrontal cortex attenuate the potentiation of amphetamine-induced locomotion by repeated neurotensin receptor activation. Brain research 20040220
Thalamic paraventricular nucleus lesions facilitate central amygdala neuronal responses to acute psychological stress. Brain research 20040206
Striatal neurons in striatal grafts are derived from both post-mitotic cells and dividing progenitors. The European journal of neuroscience 20040201
Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector. The European journal of neuroscience 20040201
Radial and tangential neuronal migration disorder in ibotenate-induced cortical lesions in hamsters: immunohistochemical study of reelin, vimentin, and calretinin. Journal of child neurology 20040201
Role of the medial prefrontal cortex in N-methyl-D-aspartate receptor antagonist induced sensorimotor gating deficit in rats. Neuroscience letters 20040123
The development of mother-infant interactions after neonatal amygdala lesions in rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040121
Pretraining or previous non-spatial experience improves spatial learning in the Morris water maze of nucleus basalis lesioned rats. Behavioural brain research 20040105
Post-pubertal adrenergic changes in rats with neonatal lesions of the ventral hippocampus. Neuropharmacology 20040101
Intralaminar thalamic nuclei lesions: widespread impact on dopamine denervation-mediated cellular defects in the rat basal ganglia. Journal of neuropathology and experimental neurology 20040101
Role of tissue-derived plasminogen activator (t-PA) in an excitotoxic mouse model of neonatal white matter lesions. Journal of neuropathology and experimental neurology 20040101
Intraparenchymal nerve growth factor improves behavioral deficits while minimizing the adverse effects of intracerebroventricular delivery. Neuroscience 20040101
Methylphenidate and MK-801, an N-methyl-d-aspartate receptor antagonist: shared biological properties. Neuroscience 20040101
Trace eyeblink conditioning is hippocampally dependent in mice. Hippocampus 20040101
Excitotoxic lesions of the pre- and parasubiculum disrupt the place fields of hippocampal pyramidal cells. Hippocampus 20040101
An examination of d-amphetamine self-administration in pedunculopontine tegmental nucleus-lesioned rats. Neuroscience 20040101
Argyrophilic dark neurons represent various states of neuronal damage in brain insults: some come to die and others survive. Neuroscience 20040101
Chronic stress enhances ibotenic acid-induced damage selectively within the hippocampal CA3 region of male, but not female rats. Neuroscience 20040101
Differential contributions of dorsal hippocampal subregions to memory acquisition and retrieval in contextual fear-conditioning. Hippocampus 20040101
Effect of memantine on the levels of glial cells, neuropeptides, and peptide-degrading enzymes in rat brain regions of ibotenic acid-treated alzheimer's disease model. Neuroscience 20040101
Effects of neonatal excitotoxic lesions of the entorhinal cortex on cognitive functions in the adult rat. Neuroscience 20040101
[Proliferation and differentiation of neural stem cells within the subependymal layer of lateral brain ventricles in response to the neurodegenerative process in the striatum]. Acta medica (Hradec Kralove). Supplementum 20040101
Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor. Biological psychiatry 20031201
Anxiolysis followed by anxiogenesis relates to coping and corticosterone after medial prefrontal cortical damage in rats. Brain research 20031128
Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. The Journal of neuroscience : the official journal of the Society for Neuroscience 20031119
Hypothalamic regulation of pancreatic secretion is mediated by central cholinergic pathways in the rat. The Journal of physiology 20031015
Lesions of the diagonal band of broca enhance drinking in the rat. Journal of neuroendocrinology 20031001
Differential contributions of the basolateral and central nuclei of the amygdala in the negative affective component of chemical somatic and visceral pains in rats. The European journal of neuroscience 20031001
The medial prefrontal cortex differentially regulates stress-induced c-fos expression in the forebrain depending on type of stressor. The European journal of neuroscience 20031001
Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound. Brain research 20030919
Potent mammalian cerebroprotection and neuronal cell death inhibition are afforded by a synthetic antioxidant analogue of marine invertebrate cell protectant ovothiols. The European journal of neuroscience 20030901
Learning and memory impairments in Kv beta 1.1-null mutants are rescued by environmental enrichment or ageing. The European journal of neuroscience 20030901
Evaluation of radioiodinated (-)-o-iodovesamicol as a radiotracer for mapping the vesicular acetylcholine transporter. Annals of nuclear medicine 20030901
Ionic interaction of [11C]-N,alpha-dimethylbenzylamine (DMBA) in rodent brain. Annals of nuclear medicine 20030901
Chronic stress alters behavior in the conditioned defensive burying test: role of the posterior paraventricular thalamus. Pharmacology, biochemistry, and behavior 20030901
Beta-lactams as versatile synthons for homochiral ibotenate analogues with potential for activity at glutamate receptors. Organic & biomolecular chemistry 20030807
Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo. Journal of neurochemistry 20030801
Neurodevelopmental animal models of schizophrenia: effects on prepulse inhibition. Current molecular medicine 20030801
Functional disconnection of the medial prefrontal cortex and subthalamic nucleus in attentional performance: evidence for corticosubthalamic interaction. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030702
Bilateral lesions of the insular cortex or of the prefrontal cortex block the association between taste and odor in the rat. Neurobiology of learning and memory 20030701
Gene expression in dopamine and GABA systems in an animal model of schizophrenia: effects of antipsychotic drugs. The European journal of neuroscience 20030701
Anisotropic functional connections between the auditory cortex and area 18a in rat cerebral slices. Neuroscience research 20030601
The effect on motor cortical neuronal development of focal lesions to the sub-cortical white matter in the neonatal rat: a model for periventricular leukomalacia. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20030601
Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin. Molecular and biochemical parasitology 20030601
The effects of selective ibotenate lesions of the hippocampus on conditioned inhibition and extinction. Cognitive, affective & behavioral neuroscience 20030601
Comparative behavioral changes between male and female postpubertal rats following neonatal excitotoxic lesions of the ventral hippocampus. Brain research 20030530
Selective hippocampal lesions do not increase adrenocortical activity. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515
Neuroprotective properties of tianeptine: interactions with cytokines. Neuropharmacology 20030501
Supraspinal contribution to development of both tonic nociception and referred mirror hyperalgesia: a comparative study between formalin test and bee venom test in the rat. Anesthesiology 20030501
Pharmacological properties of l-glutamate receptors associated with the crayfish hindgut. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 20030501
The effects of ibotenic hippocampal lesions on discriminative fear conditioning to context in mice: impairment or facilitation depending on the associative value of a phasic explicit cue. The European journal of neuroscience 20030501
Excitotoxic lesions of the medial prefrontal cortex attenuate fear responses in the elevated-plus maze, social interaction and shock probe burying tests. Brain research 20030418
Effects of T-82, a novel acetylcholinesterase inhibitor, on impaired learning and memory in passive avoidance task in rats. European journal of pharmacology 20030328
Effects of interleukin-10 on neonatal excitotoxic brain lesions in mice. Brain research. Developmental brain research 20030314
Involvement of the entorhinal cortex in the stress response to immobilization, but not to insulin-induced hypoglycaemia. Journal of neuroendocrinology 20030301
Effects of a mediodorsal thalamus lesion on prefrontal inhibitory circuitry: implications for schizophrenia. Biological psychiatry 20030301
One-trial memory for object-place associations after separate lesions of hippocampus and posterior parahippocampal region in the monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301
The substance P (NK1) receptor antagonist L-760735 inhibits fear conditioning in gerbils. Neuropharmacology 20030301
Fructose-1,6-biphosphate prevents excitotoxic neuronal cell death in the neonatal mouse brain. Brain research. Developmental brain research 20030216
Time-dependent relationship between the dorsal hippocampus and the prefrontal cortex in spatial memory. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030215
The alpha2-adrenoceptor agonist dexmedetomidine converges on an endogenous sleep-promoting pathway to exert its sedative effects. Anesthesiology 20030201
Amanita muscaria: chemistry, biology, toxicology, and ethnomycology. Mycological research 20030201
Selective neurodegeneration of hippocampus and entorhinal cortex correlates with spatial learning impairments in rats with bilateral ibotenate lesions of ventral subiculum. Brain research 20030117
The amygdala: is it an essential component of the neural network for social cognition? Neuropsychologia 20030101
Theta- and movement velocity-related firing of hippocampal neurons is disrupted by lesions centered on the perirhinal cortex. Hippocampus 20030101
Preserved performance in a hippocampal-dependent spatial task despite complete place cell remapping. Hippocampus 20030101
Hippocampal lesions and discrimination performance of mice in the radial maze: sparing or impairment depending on the representational demands of the task. Hippocampus 20030101
Distribution and binding parameters of GABAA receptors in the thalamic nuclei of Macaca mulatta and changes caused by lesioning in the globus pallidus and reticular thalamic nucleus. Neuroscience 20030101
Early microglial activation following neonatal excitotoxic brain damage in mice: a potential target for neuroprotection. Neuroscience 20030101
The perirhinal-entorhinal cortex, but not the hippocampus, is critical for expression of individual recognition in the context of the Coolidge effect. Neuroscience 20030101
Neonatal ventral hippocampus lesion leads to reductions in nerve growth factor inducible-B mRNA in the prefrontal cortex and increased amphetamine response in the nucleus accumbens and dorsal striatum. Neuroscience 20030101
Effect of unilateral ibotenate lesions of the ventral tegmental area on cortical and hippocampal EEG in freely behaving rats. Acta neurobiologiae experimentalis 20030101
Assessment of locus and extent of neurotoxic lesions in monkeys using neuroimaging techniques: a replication. Journal of neuroscience methods 20021215
Lateral hypothalamic lesions impair flavour-nutrient and flavour-toxin trace learning in rats. The European journal of neuroscience 20021201
Modulation of cell death by mouse genotype: differential vulnerability to excitatory amino acid-induced lesions. Experimental neurology 20021201
Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus. Brain research 20021122
In vivo conversion of racemized beta-amyloid ([D-Ser 26]A beta 1-40) to truncated and toxic fragments ([D-Ser 26]A beta 25-35/40) and fragment presence in the brains of Alzheimer's patients. Journal of neuroscience research 20021101
Stimulation of N-methyl-D-aspartate (NMDA) receptors inhibits neuronal migration in embryonic cerebral cortex: a tissue culture study. Brain research. Developmental brain research 20021020
Delayed mesolimbic system alteration in a developmental animal model of schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience 20021015
Subthalamic GAD gene therapy in a Parkinson's disease rat model. Science (New York, N.Y.) 20021011
Activation of different vestibular subnuclei evokes differential respiratory and pressor responses in the rat. The Journal of physiology 20021001
Cellular localization of cannabinoid receptors and activated G-proteins in rat anterior cingulate cortex. Life sciences 20020927
Chemical lesions of the nucleus isthmi increase the hypoxic and hypercarbic drive to breathing of toads. Respiratory physiology & neurobiology 20020904
Reduced N-acetylaspartate in prefrontal cortex of adult rats with neonatal hippocampal damage. Cerebral cortex (New York, N.Y. : 1991) 20020901
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4. The Journal of pharmacology and experimental therapeutics 20020901
Glucocorticoid treatment in an ischaemic-like excitotoxic model of periventricular leucomalacia in mice. BJOG : an international journal of obstetrics and gynaecology 20020901
Acute neuroinflammation exacerbates excitotoxicity in rat hippocampus in vivo. Experimental neurology 20020901
Cholinergic receptor blockade in prefrontal cortex and lesions of the nucleus basalis: implications for allocentric and egocentric spatial memory in rats. Behavioural brain research 20020821
Reduced prepulse inhibition in rats with entorhinal cortex lesions. Behavioural brain research 20020821
An examination of the effects of bilateral excitotoxic lesions of the pedunculopontine tegmental nucleus on responding to sucrose reward. Behavioural brain research 20020821
Effects of ibotenic acid lesions of the nucleus accumbens on paced mating behavior in the female rat. Behavioral neuroscience 20020801
Ibotenic acid lesions of the medial septum retard delay eyeblink conditioning in rabbits (Oryctolagus cuniculus). Behavioral neuroscience 20020801
Epileptiform activity extinguished by amygdala infusion of the neurotoxin ibotenate in a rat model of temporal lobe epilepsy. Journal of neurosurgery 20020801
Neither ibotenic acid nor volkensin lesions of the nucleus accumbens shell affect the expression of cocaine sensitization. The European journal of neuroscience 20020801
Thalamocortical dysrhythmia and the thalamic reticular nucleus in behaving rats. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20020701
The hippocampus and disambiguation of overlapping sequences. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020701
Anterograde amnesia and temporally graded retrograde amnesia for a nonspatial memory task after lesions of hippocampus and subiculum. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020601
Anxiolytic effects of cytotoxic hippocampal lesions in rats. Behavioral neuroscience 20020601
Deficits in reward sensitivity in a neurodevelopmental rat model of schizophrenia. Psychopharmacology 20020601
The effect of the destruction of the caudate-putamen on the development of amygdaloid kindling and kindled seizures. Fukushima journal of medical science 20020601
17 beta-estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons. Brain research 20020517
Low levels of estrogen significantly diminish axonal sprouting after entorhinal cortex lesions in the mouse. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020515
Role of the rostral medial medulla in the development of primary and secondary hyperalgesia after incision in the rat. Anesthesiology 20020501
Lesions of extrastriate cortex and consequences for visual guidance during locomotion. Experimental brain research 20020501
The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation. Pain 20020501
Activity-dependent receptive field changes in the surround of adult cat visual cortex lesions. The European journal of neuroscience 20020501
Opposing roles for medial and central amygdala in the initiation of noradrenergic cell responses to a psychological stressor. The European journal of neuroscience 20020501
Medial versus lateral parabrachial nucleus lesions in the rat: effects on mercaptoacetate-induced feeding and conditioned taste aversion. Brain research bulletin 20020501
Effects of excitotoxic median raphe lesions on scopolamine-induced working memory deficits in inhibitory avoidance. The International journal of neuroscience 20020501
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Effects of acute and subchronic administration of dexefaroxan, an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents. The Journal of pharmacology and experimental therapeutics 20020401
Excitotoxic lesions of the rhinal cortex in the baboon differentially affect visual recognition memory, habit memory and spatial executive functions. The European journal of neuroscience 20020401
Performance of different synchronization measures in real data: a case study on electroencephalographic signals. Physical review. E, Statistical, nonlinear, and soft matter physics 20020401
mRNA expression alterations of inward rectifier potassium channels in rat brain with cholinergic impairment. Neuroscience letters 20020329
Determination of acetylcholine and dopamine content in thalamus and striatum after excitotoxic lesions of the pedunculopontine tegmental nucleus in rats. Neuroscience letters 20020329
Effects of excitotoxic median raphe lesion on working memory deficits produced by the dorsal hippocampal muscarinic receptor blockade in the inhibitory avoidance in rats. Brain research bulletin 20020315
Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020301
Behavioral effects of excitotoxic lesions of ventral medial prefrontal cortex in the rat are hemisphere-dependent. Brain research 20020208
Cell dynamics of calretinin-immunoreactive neurons in the rostral migratory stream after ibotenate-induced lesions in the forebrain. Neuroscience research 20020201
Effects of alpha(2)-adrenoceptor agonists on perinatal excitotoxic brain injury: comparison of clonidine and dexmedetomidine. Anesthesiology 20020101
Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge. Annals of neurology 20020101
Electrolytic and ibotenic acid lesions of the nucleus basalis magnocellularis interrupt long-term retention, but not acquisition of two-way active avoidance, in rats. Experimental brain research 20020101
Hippocampal dysfunction and behavioral deficit in the water maze in mice: an unresolved issue? Brain research bulletin 20020101
Effects of brain histamine on memory deficit induced by nucleus basalis-lesion in rats. Acta pharmacologica Sinica 20020101
Excitotoxic lesions of the pedunculopontine differentially mediate morphine- and d-amphetamine-evoked striatal dopamine efflux and behaviors. Neuroscience 20020101
The effect of excitotoxic lesions of the pedunculopontine tegmental nucleus on performance of a progressive ratio schedule of reinforcement. Neuroscience 20020101
Effects of lesions to the hippocampus or the fornix on allocentric conditional associative learning in rats. Hippocampus 20020101
The reaction of the subependymal layer of lateral brain ventricles to striatal ibotenic acid lesions in a long-term study. Acta histochemica 20020101
[An animal model of Huntington's disease: the development of histopathological changes within the neurotoxic lesions of the striatum in long-term surviving rats]. Acta medica (Hradec Kralove). Supplementum 20020101
Neuroprotective effects of leptin in vivo and in vitro. Neuroreport 20011221
Subthalamo-pallido-striatal axis: a feedback system in the basal ganglia. Neuroreport 20011204
The effects of excitotoxic lesions of the pedunculopontine tegmental nucleus on conditioned place preference to 4%, 12% and 20% sucrose solutions. Brain research bulletin 20011201
Differentiation of GABA(A) receptors in subcortical heterotopias: subunit distribution of displaced cortex reflects original commitment. Neuroreport 20011116
Role of Barrington's nucleus in the activation of rat locus coeruleus neurons by colonic distension. Brain research 20011102
Involvement of the bed nucleus of the stria terminalis in hippocampal cholinergic system-mediated activation of the hypothalamo--pituitary--adrenocortical axis in rats. Brain research 20011019
Reduction in opioid- and cannabinoid-induced antinociception in rhesus monkeys after bilateral lesions of the amygdaloid complex. The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015
Subthalamic nucleus lesions are neuroprotective against terminal 6-OHDA-induced striatal lesions and restore postural balancing reactions. Experimental neurology 20011001
Forebrain muscarinic control of micturition reflex in rats. Neuropharmacology 20011001
Prolonged survival of axons terminating within lesions of cat visual cortex. Neuroscience letters 20010921
Region-specific decrease in 5-HT1A and 5-HT1B binding sites after intra-hippocampal ibotenic acid injections in the rat. Neuroscience letters 20010907
Sustained, long-lasting inhibition of nitric oxide synthase aggravates the neural damage in some models of excitotoxic brain injury. Brain research bulletin 20010901
Stimulation of the subthalamic vasodilator area and fastigial nucleus independently protects the brain against focal ischemia. Brain research 20010831
Experimental localization of Kv1 family voltage-gated K+ channel alpha and beta subunits in rat hippocampal formation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815
Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain. Pediatric research 20010801
Long-term cortical atrophy after excitotoxic striatal lesion: effects of intrastriatal fetal-striatum grafts and implications for Huntington disease. Journal of neuropathology and experimental neurology 20010801
Negative chronotropism of the heart is inhibited with lesions of the caudal medulla in the rat. Brain research 20010727
Neurotoxic lesions of perirhinal cortex impair visual recognition memory in rhesus monkeys. Neuroreport 20010703
Contrasting effects of ibotenate lesions of the paraventricular nucleus and subparaventricular zone on sleep-wake cycle and temperature regulation. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701
Ibotenate injections into the pre- and parasubiculum provide partial protection against kainate-induced epileptic damage in layer III of rat entorhinal cortex. Epilepsia 20010701
Impaired recognition of the goal location during spatial navigation in rats with hippocampal lesions. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010615
Instability in the place field location of hippocampal place cells after lesions centered on the perirhinal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601
Neurons of a limited subthalamic area mediate elevations in cortical cerebral blood flow evoked by hypoxia and excitation of neurons of the rostral ventrolateral medulla. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010601
Alterations in ApoE and ApoJ in relation to degeneration and regeneration in a mouse model of entorhinal cortex lesion. Experimental neurology 20010601
The effects of bilateral lesions of the amygdala on dyadic social interactions in rhesus monkeys (Macaca mulatta). Behavioral neuroscience 20010601
Dopamine D1 receptor activation in the medial prefrontal cortex prevents the expression of cocaine sensitization. The Journal of pharmacology and experimental therapeutics 20010501
Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010501
Developmental and stress-related changes of neurotrophic factor gene expression in an animal model of schizophrenia. Molecular psychiatry 20010501
Cytotoxic lesions of the hippocampus increase social investigation but do not impair social-recognition memory. Experimental brain research 20010501
Lesions of the pedunculopontine tegmental nucleus reduce paradoxical sleep (PS) propensity: evidence from a short-term PS deprivation study in rats. The European journal of neuroscience 20010501
Parabrachial nucleus modulates cardiovascular responses to blood loss. American journal of physiology. Regulatory, integrative and comparative physiology 20010401
Medial versus lateral parabrachial nucleus lesions in the rat: effects on cholecystokinin- and D-fenfluramine-induced anorexia. Brain research 20010316
The primate amygdala mediates acute fear but not the behavioral and physiological components of anxious temperament. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010315
Neurohistological and behavioral evidence for lordosis-inhibiting tract from lateral septum to periaqueductal gray in male rats. The Journal of comparative neurology 20010312
Expression of AMPA receptor flip and flop mRNAs in the nucleus accumbens and prefrontal cortex after neonatal ventral hippocampal lesions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010301
Glycine reduces novelty- and methamphetamine-induced locomotor activity in neonatal ventral hippocampal damaged rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010301
Lesion of the perinuclear zone attenuates cardiac sensitivity of vasopressinergic supraoptic neurons. American journal of physiology. Regulatory, integrative and comparative physiology 20010301
Impairments in visual discrimination learning and recognition memory produced by neurotoxic lesions of rhinal cortex in rhesus monkeys. The European journal of neuroscience 20010301
Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain. The Journal of clinical investigation 20010215
Antiparkinsonian and behavioral effects of inactivation of the substantia nigra pars reticulata in hemiparkinsonian primates. Experimental neurology 20010201
Excitotoxicity induces changes in rat brain gangliosides. Neuroscience research 20010201
The effects of excitotoxic lesions of the nucleus accumbens core or shell regions on intravenous heroin self-administration in rats. Psychopharmacology 20010201
The effects of nucleus accumbens core and shell lesions on intravenous heroin self-administration and the acquisition of drug-seeking behaviour under a second-order schedule of heroin reinforcement. Psychopharmacology 20010201
Dorsal and ventral medullary catecholamine cell groups contribute differentially to systemic interleukin-1beta-induced hypothalamic pituitary adrenal axis responses. Neuroendocrinology 20010201
Excitotoxic lesions of the pre- and parasubiculum disrupt object recognition and spatial memory processes. Behavioral neuroscience 20010201
Basal midbrain modulation of tonic immobility in the toad Bufo paracnemis. Physiology & behavior 20010201
Long-term neurochemical changes after visual cortical lesions in the adult cat. The Journal of comparative neurology 20010108
Regulation by the medial amygdala of copulation and medial preoptic dopamine release. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010101
Subicular lesions cause dendritic atrophy in CA1 and CA3 pyramidal neurons of the rat hippocampus. Neuroscience 20010101
Locomotor activity induced by the non-competitive N-methyl-D-aspartate antagonist, MK-801: role of nucleus accumbens efferent pathways. Neuroscience 20010101
Rats with lesions of the hippocampus are impaired on the delayed nonmatching-to-sample task. Hippocampus 20010101
Drastic neuronal loss in vivo by beta-amyloid racemized at Ser(26) residue: conversion of non-toxic [D-Ser(26)]beta-amyloid 1-40 to toxic and proteinase-resistant fragments. Neuroscience 20010101
Ibotenate lesion of the ventromedial hypothalamus lowers hyperthermic effects of prostaglandin E1. Physiological research 20010101
Dissociation between the attentional functions mediated via basal forebrain cholinergic and GABAergic neurons. Neuroscience 20010101
MRI-Based evaluation of locus and extent of neurotoxic lesions in monkeys. Hippocampus 20010101
Ibotenic acid lesions in the pedunculopontine region result in recovery of visual orienting in the hemianopic cat. Neuroscience 20010101
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. Journal of neurochemistry 20001201
Ouabain- and central sodium-induced hypertension depend on the ventral anteroventral third ventricle region. The American journal of physiology 19990101
Effect of Trasina, an ayurvedic herbal formulation, on experimental models of Alzheimer's disease and central cholinergic markers in rats. Journal of alternative and complementary medicine (New York, N.Y.) 19970101
RJR-2403: a nicotinic agonist with CNS selectivity II. In vivo characterization. The Journal of pharmacology and experimental therapeutics 19961201
Gonadectomy does not prevent novelty or drug-induced motor hyperresponsiveness in rats with neonatal hippocampal damage. Brain research. Developmental brain research 19940415
Delayed effects of neonatal hippocampal damage on haloperidol-induced catalepsy and apomorphine-induced stereotypic behaviors in the rat. Brain research. Developmental brain research 19931015
A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line. Brain research 19930813
Neuronal cell bodies in the hypothalamic paraventricular nucleus mediate stress-induced renin and corticosterone secretion. Neuroendocrinology 19890701
Paradoxical anticonvulsant activity of the excitatory amino acid N-methyl-D-aspartate in the rat caudate-putamen. Proceedings of the National Academy of Sciences of the United States of America 19870301
Dopamine dependent behaviours in rats with bilateral ibotenic acid-induced lesions of the globus pallidus. Brain research bulletin 19860101
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