1,3-Dithiole-2-thione
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Dietary modulation of the biotransformation and genotoxicity of aflatoxin B(1). | Toxicology 20120928 |
Dithiolethiones inhibit NF-κB activity via covalent modification in human estrogen receptor-negative breast cancer. | Cancer research 20120501 |
6,6-Dimethyl-2H,5H,6H,7H-1,3-dithiolo[4,5-f][1,5,3]dithia-silepin-2-one. | Acta crystallographica. Section E, Structure reports online 20120401 |
2-Methyl-sulfanyl-5,6-dihydro-2H-1,3-dithiolo[4,5-b][1,4]dioxin-2-ium tetra-fluoro-borate. | Acta crystallographica. Section E, Structure reports online 20120401 |
Mechanism of chemical activation of Nrf2. | PloS one 20120101 |
The yin and yang of nrf2-regulated selenoproteins in carcinogenesis. | International journal of cell biology 20120101 |
The antioxidant 3H-1,2-dithiole-3-thione potentiates advanced glycation end-product-induced oxidative stress in SH-SY5Y cells. | Experimental diabetes research 20120101 |
2-Sulfanylidene-1,3-dithiolo[4,5-b]naphtho-[2,3-e][1,4]dithiine-5,10-dione. | Acta crystallographica. Section E, Structure reports online 20111101 |
5,6-Dihydro-2H-1,3-dithiolo[4,5-b][1,4]dioxine-2-thione. | Acta crystallographica. Section E, Structure reports online 20110601 |
S-diclofenac protects against doxorubicin-induced cardiomyopathy in mice via ameliorating cardiac gap junction remodeling. | PloS one 20110101 |
5,6-Diamino-1,3-benzodithiole-2-thione. | Acta crystallographica. Section E, Structure reports online 20101201 |
New aryldithiolethione derivatives as potent histone deacetylase inhibitors. | Bioorganic & medicinal chemistry 20100615 |
4,6,7,9,10,12,13,15,16,18-Decahydro-1,3-dithiolo[4,5-l][1,4,7,10,15]trioxadithia-cyclo-hepta-decine-2-thione. | Acta crystallographica. Section E, Structure reports online 20100601 |
Dithiolethione modified valproate and diclofenac increase E-cadherin expression and decrease proliferation of non-small cell lung cancer cells. | Lung cancer (Amsterdam, Netherlands) 20100501 |
Modulation of thiol homeostasis induced by H2S-releasing aspirin. | Free radical biology & medicine 20100501 |
HPLC determination of novel dithiolethione containing drugs and its application for in vivo studies in rats. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201 |
PSMB7 is associated with anthracycline resistance and is a prognostic biomarker in breast cancer. | British journal of cancer 20100119 |
Redox-active tetrathiafulvalene and dithiolene compounds derived from allylic 1,4-diol rearrangement products of disubstituted 1,3-dithiole derivatives. | Beilstein journal of organic chemistry 20100101 |
Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity. | Oncogene 20091029 |
Therapeutic potential of dithiolethiones for hepatic diseases. | Pharmacology & therapeutics 20091001 |
Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect. | Molecular cancer therapeutics 20091001 |
Structural and vibrational studies of molecular conductors using quantum mechanical methods: 1,3-Dithiole-2-thione, 1,3-dithiole-2-one, 1,3-dioxole-2-one and 1,3-dioxole-2-thione. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090915 |
Hydrogen peroxide is a second messenger in phase 2 enzyme induction by cancer chemopreventive dithiolethiones. | Chemical research in toxicology 20090817 |
4,6,7,9,10,12-Hexahydro-1,3-dithiolo[4,5-f][1,4,9]oxadithia-cyclo-undecine-2-thione. | Acta crystallographica. Section E, Structure reports online 20090701 |
Novel dithiolethione-modified nonsteroidal anti-inflammatory drugs in human hepatoma HepG2 and colon LS180 cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090315 |
Chemical genomics of cancer chemopreventive dithiolethiones. | Carcinogenesis 20090301 |
3-(2-Thioxo-1,3-dithiol-4-ylsulfan-yl)-propane-nitrile. | Acta crystallographica. Section E, Structure reports online 20081101 |
New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity. | Bioorganic & medicinal chemistry letters 20080315 |
An Hg2+-gated chiral molecular switch created by using binaphthalene molecules with two anthracene units and two 1,3-dithiole-2-thione (1,3-dithiole-2-one) units. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
Induction of Nrf2-regulated genes by 3H-1, 2-dithiole-3-thione through the ERK signaling pathway in murine keratinocytes. | European journal of pharmacology 20071222 |
Identification of a novel class of dithiolethiones that prevent hepatic insulin resistance via the adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway. | Hepatology (Baltimore, Md.) 20070901 |
Tissue specific increase of the catalytic subunits of the 26S proteasome by indirect antioxidant dithiolethione in mice: enhanced activity for degradation of abnormal protein. | Life sciences 20070606 |
Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target. | PLoS medicine 20070601 |
Modulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid. | British journal of pharmacology 20070501 |
The thiol antioxidant 1,2-dithiole-3-thione stimulates the expression of heat shock protein 70 in dopaminergic PC12 cells. | Neuroscience letters 20070406 |
Thiolated pi-extended tetrathiafulvalenes: versatile multifunctional pi-systems. | The Journal of organic chemistry 20070216 |
The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties. | Bioinorganic chemistry and applications 20070101 |
The chemopreventive efficacy of inhaled oltipraz particulates in the B[a]P-induced A/J mouse lung adenoma model. | Carcinogenesis 20060801 |
The antioxidant anethole dithiolethione inhibits monoamine oxidase-B but not monoamine oxidase A activity in extracts of cultured astrocytes. | Journal of neural transmission (Vienna, Austria : 1996) 20060501 |
Reactions Between Chalcogen Donors and Dihalogens/Interalogens: Typology of Products and Their Characterization by FT-Raman Spectroscopy. | Bioinorganic chemistry and applications 20060101 |
1,3-Dithiole-2-thione derivatives featuring an anthracene unit: new selective chemodosimeters for Hg(II) ion. | Chemical communications (Cambridge, England) 20050428 |
Safety and efficacy of weekly oral oltipraz in chronic smokers. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050401 |
NF-kappaB activation by the chemopreventive dithiolethione oltipraz is exerted through stimulation of MEKK3 signaling. | The Journal of biological chemistry 20040618 |
Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz. | Carcinogenesis 20031201 |
Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz. | Journal of the National Cancer Institute 20030101 |
Chemoprotective potential of phase 2 enzyme inducers. | Expert review of anticancer therapy 20021001 |