L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparagine
| Title | Journal |
|---|---|
| TCDD and omeprazole prime platelets through the aryl hydrocarbon receptor (AhR) non-genomic pathway. | Toxicology letters 20150519 |
| Antioxidative properties of hydrogen sulfide may involve in its antiadhesive action on blood platelets. | Clinical biochemistry 20121201 |
| The activation of protease-activated receptor 1 mediates proliferation and invasion of nasopharyngeal carcinoma cells. | Oncology reports 20120701 |
| Thrombin stimulates integrin β1-dependent adhesion of human pancreatic cancer cells to vitronectin through protease-activated receptor (PAR)-1. | Hepato-gastroenterology 20120101 |
| PKC inhibition markedly enhances Ca2+ signaling and phosphatidylserine exposure downstream of protease-activated receptor-1 but not protease-activated receptor-4 in human platelets. | Journal of thrombosis and haemostasis : JTH 20110801 |
| Platelet function following trauma. A multiple electrode aggregometry study. | Thrombosis and haemostasis 20110801 |
| Negative regulation of Gq-mediated pathways in platelets by G(12/13) pathways through Fyn kinase. | The Journal of biological chemistry 20110708 |
| The effect of intravenous high-dose methylprednisolone on platelet reactivity assessed with multiple electrode aggregometry. | Thrombosis and haemostasis 20110601 |
| Increased platelet aggregation and in vivo platelet activation after granulocyte colony-stimulating factor administration. A randomised controlled trial. | Thrombosis and haemostasis 20110401 |
| In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation. | Journal of thrombosis and haemostasis : JTH 20110301 |
| Hemostatic function of buffy coat platelets in additive solution treated with pathogen reduction technology. | Transfusion 20110201 |
| Measurement of platelet function in dogs using a novel impedance aggregometer. | Veterinary journal (London, England : 1997) 20100801 |
| Pairwise agonist scanning predicts cellular signaling responses to combinatorial stimuli. | Nature biotechnology 20100701 |
| A point-of-care assessment of the effects of desmopressin on impaired platelet function using multiple electrode whole-blood aggregometry in patients after cardiac surgery. | Anesthesia and analgesia 20100301 |
| Mild and moderate hypothermia increases platelet aggregation induced by various agonists: a whole blood in vitro study. | Platelets 20100101 |
| Is TRAP-6 suitable as a positive control for platelet reactivity when assessing response to clopidogrel? | Platelets 20100101 |
| Valproic acid and all trans retinoic acid differentially induce megakaryopoiesis and platelet-like particle formation from the megakaryoblastic cell line MEG-01. | Platelets 20100101 |
| Preliminary evidence for a matrix metalloproteinase-2 (MMP-2)-dependent shedding of soluble CD40 ligand (sCD40L) from activated platelets. | Platelets 20090901 |
| Proteinase-activated receptor-1 activation presynaptically enhances spontaneous glutamatergic excitatory transmission in adult rat substantia gelatinosa neurons. | Journal of neurophysiology 20090701 |
| Protein kinase C-mediated phosphorylation and activation of PDE3A regulate cAMP levels in human platelets. | The Journal of biological chemistry 20090501 |
| Impaired activation of platelets lacking protein kinase C-theta isoform. | Blood 20090312 |
| Histone H3 as a novel substrate for MAP kinase phosphatase-1. | American journal of physiology. Cell physiology 20090201 |
| The effect of ex vivo anticoagulants on whole blood platelet aggregation. | Platelets 20090201 |
| Whole-blood aggregometry: are there any limits with regard to platelet counts? | Acta anaesthesiologica Scandinavica 20090101 |
| Endothelium-derived hyperpolarizing factor mediated relaxations in pig coronary arteries do not involve Gi/o proteins. | Acta pharmacologica Sinica 20081201 |
| Differential effects of serine proteases on the migration of normal and tumor cells: implications for tumor microenvironment. | Integrative cancer therapies 20081201 |
| Modulation of tissue factor and tissue factor pathway inhibitor-1 by neutrophil proteases. | Thrombosis and haemostasis 20081201 |
| Coordinate activation of human platelet protease-activated receptor-1 and -4 in response to subnanomolar alpha-thrombin. | The Journal of biological chemistry 20081003 |
| Complement activation triggered by chondroitin sulfate released by thrombin receptor-activated platelets. | Journal of thrombosis and haemostasis : JTH 20080801 |
| The periodontal pathogen Porphyromonas gingivalis sensitises human blood platelets to epinephrine. | Platelets 20080801 |
| The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine. | The Journal of biological chemistry 20080704 |
| Development of proteomic signatures of platelet activation using surface-enhanced laser desorption/ionization technology in a clinical setting. | American journal of clinical pathology 20080601 |
| Delayed inhibition of agonist-induced granulocyte-platelet aggregation after low-dose sevoflurane inhalation in humans. | Anesthesia and analgesia 20080601 |
| Multiple electrode aggregometry and P2Y(12) antagonists. | Thrombosis and haemostasis 20080601 |
| Fluoxetine (Prozac) augments platelet activation mediated through protease-activated receptors. | Journal of thrombosis and haemostasis : JTH 20080401 |
| Elevated platelet reactivity in stable angina pectoris without significant coronary flow obstruction. | Journal of cardiovascular medicine (Hagerstown, Md.) 20080201 |
| Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080116 |
| VEGF and thrombin induce MKP-1 through distinct signaling pathways: role for MKP-1 in endothelial cell migration. | American journal of physiology. Cell physiology 20080101 |
| Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. | Thrombosis and haemostasis 20080101 |
| Regulation of protease-activated receptor (PAR) 1 and PAR4 signaling in human platelets by compartmentalized cyclic nucleotide actions. | The Journal of pharmacology and experimental therapeutics 20070801 |
| Osteosarcoma cell-calcium signaling through tissue factor-factor VIIa complex and factor Xa. | FEBS letters 20070612 |
| Platelets possess and require an active protein palmitoylation pathway for agonist-mediated activation and in vivo thrombus formation. | Arteriosclerosis, thrombosis, and vascular biology 20070601 |
| Parnaparin, a low-molecular-weight heparin, prevents P-selectin-dependent formation of platelet-leukocyte aggregates in human whole blood. | Thrombosis and haemostasis 20070601 |
| Adenosine opposes thrombin-induced inhibition of intercellular calcium wave in corneal endothelial cells. | Investigative ophthalmology & visual science 20070401 |
| Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development. | Thrombosis and haemostasis 20070301 |
| Ex vivo microvesicle formation after prolonged ischemia in renal transplantation. | Thrombosis research 20070101 |
| [Activation of cardiac contractivity of the edible snail H. pomatia under effect of thrombin. Study of role of cAMP]. | Zhurnal evoliutsionnoi biokhimii i fiziologii 20070101 |
| [Role of adenosine diphosphate in the course of thrombin signal transmission]. | Zhonghua yi xue za zhi 20061212 |
| PAR-1-dependent pp60src activation is dependent on protein kinase C and increased [Ca2+]: evidence that pp60src does not regulate PAR-1-dependent Ca2+ entry in human platelets. | Journal of thrombosis and haemostasis : JTH 20061201 |
| Platelet and monocyte activation by hyperglycemia and hyperinsulinemia in healthy subjects. | Platelets 20061201 |
| Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood. | Thrombosis and haemostasis 20061201 |
| Factor VIII is a positive regulator of platelet function. | Platelets 20061101 |
| Direct vascular effects of protease-activated receptor type 1 agonism in vivo in humans. | Circulation 20061010 |
| Comparison of the effects of PAR1 antagonists, PAR4 antagonists, and their combinations on thrombin-induced human platelet activation. | European journal of pharmacology 20060928 |
| Do heterotrimeric G proteins redistribute upon G protein-coupled receptor stimulation in platelets? | Platelets 20060901 |
| Galpha12/13- and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors. | Molecular pharmacology 20060601 |
| ThromboFix platelet stabilizer: advances in clinical platelet analyses by flow cytometry? | Platelets 20060601 |
| Actin polymerisation regulates thrombin-evoked Ca(2+) signalling after activation of PAR-4 but not PAR-1 in human platelets. | Platelets 20060501 |
| The platelet receptor for type III collagen (TIIICBP) is present in platelet membrane lipid microdomains (rafts). | Histochemistry and cell biology 20060401 |
| Fibrin sealant promotes migration and proliferation of human articular chondrocytes: possible involvement of thrombin and protease-activated receptors. | International journal of molecular medicine 20060401 |
| Agonists-induced platelet activation varies considerably in healthy male individuals: studies by flow cytometry. | Annals of hematology 20060201 |
| The influence of bromelain on platelet count and platelet activity in vitro. | Platelets 20060201 |
| Development of a time-resolved immunofluorometric assay for quantifying platelet-derived microparticles in human plasma. | Thrombosis research 20060101 |
| [Biodegradable microparticles with immobilized peptide for wound healing]. | Biomeditsinskaia khimiia 20060101 |
| The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion. | Blood 20050515 |
| Coagulation factor Xa stimulates interleukin-8 release in endothelial cells and mononuclear leukocytes: implications in acute myocardial infarction. | Arteriosclerosis, thrombosis, and vascular biology 20050201 |
| Inverse relationships between coronary blood flow obstruction and platelet reactivity in stable angina pectoris. | Platelets 20050101 |
| alpha-thrombin rapidly induces tyrosine phosphorylation of a novel, 74-78-kDa stress response protein(s) in lung fibroblast cells. | The Journal of biological chemistry 20041119 |
| Signaling mechanisms involved in protease-activated receptor-1-mediated interleukin-6 production by human gingival fibroblasts. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Induction and antimicrobial activity of platelet basic protein derivatives in human monocytes. | Journal of leukocyte biology 20041101 |
| Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1. | The Biochemical journal 20040915 |
| Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses. | Blood 20040901 |
| Variable hypocoagulant effect of fish oil intake in humans: modulation of fibrinogen level and thrombin generation. | Arteriosclerosis, thrombosis, and vascular biology 20040901 |
| Effects of inhaled thrombin receptor agonists in mice. | British journal of pharmacology 20040901 |
| The effect of ASA on platelet activation during apheresis and on in-vitro properties of stored platelet concentrates. | Transfusion 20040901 |
| The effects of high molecular weight hydroxyethyl starch solutions on platelets. | Anesthesia and analgesia 20040901 |
| Soluble CD40 ligand in pulmonary arterial hypertension: possible pathogenic role of the interaction between platelets and endothelial cells. | Circulation 20040824 |
| Akt activation in platelets depends on Gi signaling pathways. | The Journal of biological chemistry 20040206 |
| PAR1 antagonism protects against experimental liver fibrosis. Role of proteinase receptors in stellate cell activation. | Hepatology (Baltimore, Md.) 20040201 |
| Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets. | The Journal of biological chemistry 20040123 |
| The anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolism. | Leukemia & lymphoma 20030901 |
| High-affinity thrombin receptor (PAR-1) ligands: a new generation of indole-based peptide mimetic antagonists with a basic amine at the C-terminus. | Bioorganic & medicinal chemistry letters 20030707 |
| Thrombin downregulates muscle acetylcholine receptors via an IP3 signaling pathway by activating its G-protein-coupled protease-activated receptor-1. | Journal of cellular physiology 20030701 |
| Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin. | The Journal of physiology 20030615 |
| Thrombin-induced Ca2+ mobilization in human gingival fibroblasts is mediated by protease-activated receptor-1 (PAR-1). | Life sciences 20030606 |
| Interleukin-7-mediated inflammation in unstable angina: possible role of chemokines and platelets. | Circulation 20030603 |
| Involvement of nitric oxide and tachykinins in the effects induced by protease-activated receptors in rat colon longitudinal muscle. | British journal of pharmacology 20030601 |
| Effects of inhibition of P2Y(1) and P2Y(12) on whole blood clotting, coagulum elasticity and fibrinolysis resistance studied with free oscillation rheometry. | Thrombosis research 20030315 |
| Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas. | Cancer 20030201 |
| Platelet phosphatidylserine exposure and procoagulant activity in clotting whole blood--different effects of collagen, TRAP and calcium ionophore A23187. | Thrombosis and haemostasis 20030101 |
| Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation. | The Biochemical journal 20021201 |
| Protease-activated receptor-1-mediated DNA synthesis in cardiac fibroblast is via epidermal growth factor receptor transactivation: distinct PAR-1 signaling pathways in cardiac fibroblasts and cardiomyocytes. | Circulation research 20020920 |
| Enhanced platelet aggregation with TRAP-6 and collagen in platelet aggregometry in patients with venous thromboembolism. | Thrombosis research 20020915 |
| Selective inhibition of protease-activated receptor 4-dependent platelet activation by YD-3. | Thrombosis and haemostasis 20020601 |
| Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling. | Blood 20020515 |
| Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1. | The Biochemical journal 20020501 |
| Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome. | Thrombosis and haemostasis 20020401 |
| Identification of functional VEGF receptors on human platelets. | FEBS letters 20020213 |
| Participation of protease-activated receptor-1 in thrombin-induced microglial activation. | Journal of neurochemistry 20020201 |
| Effect of halothane and isoflurane on binding of ADP- and TRAP-6- activated platelets to leukocytes in Whole blood. | Anesthesiology 20020101 |
| [Polymer coatings with immobilized thrombin and peptides: preparation and use for wound healing]. | Voprosy meditsinskoi khimii 20020101 |
| Thrombin and PAR-1 activating peptide increase iNOS expression in cytokine-stimulated C6 glioma cells. | Journal of neurochemistry 20011101 |
| Platelet aggregation is not initiated by platelet shape change. | Laboratory investigation; a journal of technical methods and pathology 20011101 |
| [The role of PAR family receptors in activation of mast cells in the norm and in acute inflammation in rats]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20011101 |
| Aprotinin: is it prothrombotic? | Perfusion 20010901 |
| Pharmacodynamics and pharmacokinetics of eptifibatide in patients with acute coronary syndromes: prospective analysis from PURSUIT. | Circulation 20010724 |
| Tritiated photoactivatable analogs of the native human thrombin receptor (PAR-1) agonist peptide, SFLLRN-NH2. | The journal of peptide research : official journal of the American Peptide Society 20010601 |
| Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20010401 |
| Clinical application of procedural platelet monitoring during percutaneous coronary intervention among patients at increased bleeding risk. | Journal of thrombosis and thrombolysis 20010401 |
| Systemic vascular effects of thrombin and thrombin receptor activating peptide in rats. | Thrombosis research 20010315 |
| Platelet CD40 ligand (CD40L)--subcellular localization, regulation of expression, and inhibition by clopidogrel. | Platelets 20010301 |
| Thrombin-stimulated growth, clustering, and collagen lattice contraction of human gingival fibroblasts is associated with its protease activity. | Journal of periodontology 20010301 |
| The effects of stimulating protease-activated receptor-1 and -2 in A172 human glioblastoma. | Journal of neural transmission (Vienna, Austria : 1996) 20010101 |
| Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets. | Blood 20001215 |
| In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist. | European journal of pharmacology 19991119 |
| Transcellular signaling and pharmacological modulation of thrombin-induced production of plasminogen activator inhibitor-1 in vascular smooth muscle cells. | Seminars in thrombosis and hemostasis 19980101 |
| Expression of thrombin receptors in human atherosclerotic coronary arteries leads to an exaggerated vasoconstrictory response in vitro. | Journal of cardiovascular pharmacology 19971101 |
| Thrombin stimulates wortmannin-inhibitable phosphoinositide 3-kinase and membrane blebbing in CHRF-288 cells. | The Biochemical journal 19960315 |