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Home Aminos 2-Hydroxy-5-[[[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]methyl]amino]benzoic acid

2-Hydroxy-5-[[[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]methyl]amino]benzoic acid

CAS No.:
640290-67-1
Catalog Number:
AG003AKS
Molecular Formula:
C15H8F7NO3
Molecular Weight:
383.2177
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
99%
1 week
United States
$168
- +
5mg
99%
1 week
United States
$404
- +
10mg
99%
1 week
United States
$682
- +
50mg
99%
1 week
United States
$1932
- +
100mg
99%
1 week
United States
$2904
- +
Product Description
Catalog Number:
AG003AKS
Chemical Name:
2-Hydroxy-5-[[[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]methyl]amino]benzoic acid
CAS Number:
640290-67-1
Molecular Formula:
C15H8F7NO3
Molecular Weight:
383.2177
MDL Number:
MFCD28502109
IUPAC Name:
2-hydroxy-5-[[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]methylamino]benzoic acid
InChI:
InChI=1S/C15H8F7NO3/c16-10-7(11(17)13(19)9(12(10)18)15(20,21)22)4-23-5-1-2-8(24)6(3-5)14(25)26/h1-3,23-24H,4H2,(H,25,26)
InChI Key:
HABROHXUHNHQMY-UHFFFAOYSA-N
SMILES:
Fc1c(CNc2ccc(c(c2)C(=O)O)O)c(F)c(c(c1F)C(F)(F)F)F
Properties
Complexity:
490  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
383.039g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
383.222g/mol
Monoisotopic Mass:
383.039g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
69.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.4  
Literature
Title Journal
Attenuated effects of Neu2000 on hypoxia-induced synaptic activities in a rat hippocampus. Archives of pharmacal research 20140201
Neu2000, an NR2B-selective, moderate NMDA receptor antagonist and potent spin trapping molecule for stroke. Drug news & perspectives 20101101
The functional and neuroprotective actions of Neu2000, a dual-acting pharmacological agent, in the treatment of acute spinal cord injury. Journal of neurotrauma 20100101
The novel NMDA receptor antagonist, 2-hydroxy-5-(2,3,5,6-tetrafluoro-4-trifluoromethyl-benzylamino)-benzoic acid, is a gating modifier in cultured mouse cortical neurons. Journal of neurochemistry 20090601
Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070601
Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis. Molecular pharmacology 20070401
Properties