1-β-D-Arabinofuranosyl-5-[(1E)-2-bromoethenyl]-2,4(1H,3H)-pyrimidinedione
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3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase. | Journal of medicinal chemistry 20100408 |
5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells. | Journal of medicinal chemistry 20070614 |
Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity. | Bioorganic & medicinal chemistry 20070415 |
Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides. | Antimicrobial agents and chemotherapy 20050301 |
Synthesis and antiviral activities of 1'-carbon-substituted 4'-thiothymidines. | Bioorganic & medicinal chemistry 20041015 |
Inactivity of the bicyclic pyrimidine nucleoside analogues against simian varicella virus (SVV) does not correlate with their substrate activity for SVV-encoded thymidine kinase. | Biochemical and biophysical research communications 20040319 |
In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir? | Antiviral research 20040301 |
Drug interaction ontology (DIO) for inferences of possible drug-drug interactions. | Studies in health technology and informatics 20040101 |
In vitro activity of potential anti-poxvirus agents. | Antiviral research 20030101 |
[Molecular toxicological mechanism of the lethal interactions of the new antiviral drug, sorivudine, with 5-fluorouracil prodrugs and genetic deficiency of dihydropyrimidine dehydrogenase]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020801 |
Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors. | Bioorganic & medicinal chemistry letters 20010521 |
2'-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase. | Biochemical pharmacology 20010315 |
Recent developments in herpesvirus therapy. | Herpes : the journal of the IHMF 20010301 |
Effects of light intensity, n-alcohols, water-soluble colorants, and solution viscosity on photoisomerization of sorivudine. | Pharmaceutical development and technology 20010101 |
Selective activity of various antiviral compounds against HHV-7 infection. | Antiviral research 19990801 |
Synthesis of novel 4'-C-methyl-pyrimidine nucleosides and their biological activities. | Bioorganic & medicinal chemistry letters 19990322 |
Anti-herpesvirus activity profile of 4'-thioarabinofuranosyl purine and uracil nucleosides and activity of 1-beta-D-2'-fluoro-4'-thioarabinofuranosyl guanine and 2,6-diaminopurine against clinical isolates of human cytomegalovirus. | Antiviral research 19980801 |
Structure-activity relationship of the affinity of 5-substituted uracil nucleoside analogues for varicella-zoster virus thymidine kinase and their activity against varicella-zoster virus. | Antiviral research 19970801 |
A facile, alternative synthesis of 4'-thioarabinonucleosides and their biological activities. | Journal of medicinal chemistry 19970704 |
Analysis of phosphorylation pathways of antiherpesvirus nucleosides by varicella-zoster virus-specific enzymes. | Antimicrobial agents and chemotherapy 19960401 |
Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6. | Antiviral research 19951201 |
Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 19950401 |
Synthesis and antiviral activity of 1-cyclobutyl-5-(2-bromovinyl)uracil nucleoside analogues and related compounds. | Journal of medicinal chemistry 19920515 |
Inhibition of human herpesvirus 6 replication by 9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (2HM-HBG) and other antiviral compounds. | Antimicrobial agents and chemotherapy 19901201 |
Effect of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus type 1 infection in immunosuppressed mice. | Antimicrobial agents and chemotherapy 19901201 |
Comparative activities of several nucleoside analogs against duck hepatitis B virus in vitro. | Antimicrobial agents and chemotherapy 19900701 |
Effect of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (brovavir) on experimental infections in mice with herpes simplex virus type 1 strains of different degrees of virulence. | Antimicrobial agents and chemotherapy 19900501 |
(E)-5-(2-bromovinyl)uridine requires phosphorylation by the herpes simplex virus (type 1)-induced thymidine kinase to express its antiviral activity. | Biochemical pharmacology 19890615 |
Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus types 1 and 2. | Antimicrobial agents and chemotherapy 19881001 |
Efficacies of antiherpesvirus nucleosides against two strains of herpes simplex virus type 1 in Vero and human embryo lung fibroblast cells. | Antimicrobial agents and chemotherapy 19880701 |
Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and E-5-(2-bromovinyl)-2'-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication. | Antimicrobial agents and chemotherapy 19880701 |
Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs. | Antimicrobial agents and chemotherapy 19860301 |
In vitro and in vivo antiviral activity of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) and related compounds. | Antiviral research 19840601 |
Strains of varicella-zoster virus resistant to 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil. | Antimicrobial agents and chemotherapy 19840601 |
Antiherpes activity of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil and some other 5-substituted uracil arabinosyl nucleosides in two different cell lines. | Antiviral research 19830901 |
Inhibitory effect of E-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil on herpes simplex virus replication and DNA synthesis. | Journal of virology 19820701 |
Inhibitory effects of antiherpesviral thymidine analogs against varicella-zoster virus. | Antimicrobial agents and chemotherapy 19820201 |
Antiherpes activity of [E]-5-(1-propenyl)-2'-deoxyuridine and 5-(1-propenyl)-1-beta-D-arabinofuranosyluracil. | Antiviral research 19811101 |
Differential activity of potential antiviral nucleoside analogs on herpes simplex virus-induced and human cellular thymidine kinases. | Antimicrobial agents and chemotherapy 19810901 |
Antiherpesviral and anticellular effects of 1-beta-D-arabinofuranosyl-E-5-(2-halogenovinyl) uracils. | Antimicrobial agents and chemotherapy 19810701 |