(10R,11R,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),2,7-trien-12-one
| Title | Journal |
|---|---|
| Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone. | Science (New York, N.Y.) 20150911 |
| Antiplasmodial and Cytotoxic Triterpenoids from the Bark of the Cameroonian Medicinal Plant Entandrophragma congoënse. | Journal of natural products 20150424 |
| 4'-Demethyl-deoxypodophyllotoxin glucoside isolated from Podophyllum hexandrum exhibits potential anticancer activities by altering Chk-2 signaling pathway in MCF-7 breast cancer cells. | Chemico-biological interactions 20141205 |
| Antiplasmodial and cytotoxic dibenzofurans from Preussia sp. harboured in Enantia chlorantha Oliv. | Fitoterapia 20140301 |
| Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues. | Bioorganic & medicinal chemistry 20140101 |
| Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor. | Scientific reports 20140101 |
| Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers. | Bioorganic & medicinal chemistry 20131201 |
| Enantioselective synthesis of encecaline-derived potent antimalarial agents. | Organic & biomolecular chemistry 20131114 |
| Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI). | Journal of medicinal chemistry 20131010 |
| Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives. | Journal of medicinal chemistry 20130926 |
| Investigation of acyclic uridine amide and 5'-amido nucleoside analogues as potential inhibitors of the Plasmodium falciparum dUTPase. | Bioorganic & medicinal chemistry 20130915 |
| Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives. | European journal of medicinal chemistry 20130901 |
| Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
| Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. | Journal of medicinal chemistry 20130711 |
| Antiprotozoal activity of Khaya anthotheca, (Welv.) C.D.C. a plant used by chimpanzees for self-medication. | Journal of ethnopharmacology 20130502 |
| Synthesis and in vitro antimalarial testing of neocryptolepines: SAR study for improved activity by introduction and modifications of side chains at C2 and C11 on indolo[2,3-b]quinolines. | Journal of medicinal chemistry 20130227 |
| Aminoalkyl derivatives of guanidine diaromatic minor groove binders with antiprotozoal activity. | Journal of medicinal chemistry 20130214 |
| Antibacterial and antiplasmodial constituents of Beilschmiedia cryptocaryoides. | Journal of natural products 20130125 |
| Next generation sequencing in predicting gene function in podophyllotoxin biosynthesis. | The Journal of biological chemistry 20130104 |
| Chemotherapy-induced bowel obstruction in small cell lung cancer: a case report. | Medical oncology (Northwood, London, England) 20121201 |
| Antileishmanial bis-arylimidamides: DB766 analogs modified in the linker region and bis-arylimidamide structure-activity relationships. | Bioorganic & medicinal chemistry letters 20121115 |
| Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | Bioorganic & medicinal chemistry 20121115 |
| Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents. | Bioorganic & medicinal chemistry 20121101 |
| Synthesis, characterization and biological evaluation of some novel 2,4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents. | Bioorganic & medicinal chemistry letters 20121015 |
| Quantification of limonin in human urine using solid-phase extraction by LC-MS/MS. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121015 |
| 2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani. | Bioorganic & medicinal chemistry letters 20121001 |
| Young women's experiences of managing self-treatment for anogenital warts. | Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives 20121001 |
| Adva-27a, a novel podophyllotoxin derivative found to be effective against multidrug resistant human cancer cells. | Anticancer research 20121001 |
| Anti-mycobacterial natural products from the Canadian medicinal plant Juniperus communis. | Journal of ethnopharmacology 20120928 |
| Ultrahigh pressure extraction of lignan compounds from Dysosma versipellis and purification by high-speed counter-current chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120915 |
| Topical treatments for cutaneous warts. | The Cochrane database of systematic reviews 20120912 |
| 18F-FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models. | Pediatric blood & cancer 20120901 |
| CIL-102 binds to tubulin at colchicine binding site and triggers apoptosis in MCF-7 cells by inducing monopolar and multinucleated cells. | Biochemical pharmacology 20120901 |
| IGF-1 alleviates ox-LDL-induced inflammation via reducing HMGB1 release in HAECs. | Acta biochimica et biophysica Sinica 20120901 |
| Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins. | Journal of medicinal chemistry 20120809 |
| Cytotoxic podophyllotoxin type-lignans from the steam bark of Bursera fagaroides var. fagaroides. | Molecules (Basel, Switzerland) 20120809 |
| Nordic MCL2 trial update: six-year follow-up after intensive immunochemotherapy for untreated mantle cell lymphoma followed by BEAM or BEAC + autologous stem-cell support: still very long survival but late relapses do occur. | British journal of haematology 20120801 |
| Synthesis and biological evaluation of novel 4β-(1,3,4-oxadiazole-2-amino)-podophyllotoxin derivatives. | Bioorganic & medicinal chemistry letters 20120715 |
| Antitumor agents 294. Novel E-ring-modified camptothecin-4β-anilino-4'-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents. | Bioorganic & medicinal chemistry 20120715 |
| Discovery of nitroheterocycles active against African trypanosomes. In vitro screening and preliminary SAR studies. | Bioorganic & medicinal chemistry letters 20120715 |
| Cantharidin-podophylotoxin-salicylic acid versus cryotherapy in the treatment of plantar warts: a randomized prospective study. | Journal of the European Academy of Dermatology and Venereology : JEADV 20120701 |
| The effect of light on gene expression and podophyllotoxin biosynthesis in Linum album cell culture. | Plant physiology and biochemistry : PPB 20120701 |
| Endophytic fungi: novel sources of anticancer lead molecules. | Applied microbiology and biotechnology 20120701 |
| Synthesis and evaluation of novel podophyllotoxin analogs. | Bioorganic & medicinal chemistry letters 20120701 |
| Novel 3-nitro-1H-1,2,4-triazole-based amides and sulfonamides as potential antitrypanosomal agents. | Journal of medicinal chemistry 20120614 |
| One-step bulk preparation of calcium carbonate nanotubes and its application in anticancer drug delivery. | Biological trace element research 20120601 |
| The use of sinecatechins (polyphenon E) ointment for treatment of external genital warts. | Expert opinion on biological therapy 20120601 |
| Human papillomavirus-related genital disease in the immunocompromised host: Part II. | Journal of the American Academy of Dermatology 20120601 |
| MYC+ diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation. | Blood 20120501 |
| Synthesis and anticancer activity of 2-benzylidene indanones through inhibiting tubulin polymerization. | Bioorganic & medicinal chemistry 20120501 |
| [Determination of podophyllotoxin and total lignans in Sinopodophyllum emodi]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120501 |
| The HDAC inhibitor LBH589 enhances the antimyeloma effects of the IGF-1RTK inhibitor picropodophyllin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120415 |
| Synthesis, biological evaluation, and structure-activity relationships of N-benzoyl-2-hydroxybenzamides as agents active against P. falciparum (K1 strain), Trypanosomes, and Leishmania. | Journal of medicinal chemistry 20120412 |
| Regulation by survivin of cancer cell death induced by F14512, a polyamine-containing inhibitor of DNA topoisomerase II. | Apoptosis : an international journal on programmed cell death 20120401 |
| Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: clinical implications. | International journal of oncology 20120401 |
| Condylomata acuminata in children. | The Pediatric infectious disease journal 20120401 |
| Synthesis and comparative evaluation of 4-oxa- and 4-aza-podophyllotoxins as antiproliferative microtubule destabilizing agents. | Bioorganic & medicinal chemistry letters 20120401 |
| Time-course changes in fungal elicitor-induced lignan synthesis and expression of the relevant genes in cell cultures of Linum album. | Journal of plant physiology 20120315 |
| Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4'-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents. | Bioorganic & medicinal chemistry 20120315 |
| Polygamain, a new microtubule depolymerizing agent that occupies a unique pharmacophore in the colchicine site. | Molecular pharmacology 20120301 |
| Synthesis and biological evaluation of conjugates of deoxypodophyllotoxin and 5-FU as inducer of caspase-3 and -7. | European journal of medicinal chemistry 20120301 |
| Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers. | Bioorganic & medicinal chemistry 20120215 |
| Synthesis and antitumor activity of novel aroylthiourea derivatives of podophyllotoxin. | Investigational new drugs 20120201 |
| In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin). | Journal of computer-aided molecular design 20120201 |
| Synthesis and anti-protozoal activity of novel dihydropyrrolo[3,4-d][1,2,3]triazoles. | European journal of medicinal chemistry 20120201 |
| Synthesis, characterization and in vitro biological evaluation of some novel diarylsulfonylureas as potential cytotoxic and antimicrobial agents. | Bioorganic & medicinal chemistry letters 20120115 |
| Factors affecting podophyllotoxin yield in the ex situ grown Podophyllum hexandrum, an endangered alpine native of the western Himalayas. | Journal of natural medicines 20120101 |
| Application of ultrasound as pretreatment for extraction of podophyllotoxin from rhizomes of Podophyllum peltatum. | Ultrasonics sonochemistry 20120101 |
| Manipulation of heterogeneity product in 4'-demethylepipodophyllotoxin biotransformation process by using yeast extract as nitrogen source. | Applied microbiology and biotechnology 20120101 |
| QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells. | Cancer science 20120101 |
| Synthesis and biological evaluation of 4α/4β-imidazolyl podophyllotoxin analogues as antitumor agents. | Archiv der Pharmazie 20120101 |
| Synthesis and anticancer activity of 4β-alkylamidochalcone and 4β-cinnamido linked podophyllotoxins as apoptotic inducing agents. | European journal of medicinal chemistry 20120101 |
| Isolation and Identification of Endophytic Fungi from Actinidia macrosperma and Investigation of Their Bioactivities. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Novel biotransformation process of podophyllotoxin to 4 β-sulfur-substituted podophyllum derivates with anti-tumor activity by Penicillium purpurogenum Y.J. Tang. | Current medicinal chemistry 20120101 |
| In vitro antitumour activity of stearic acid-g-chitosan oligosaccharide polymeric micelles loading podophyllotoxin. | Journal of microencapsulation 20120101 |
| Insulin-like growth factors promote vasculogenesis in embryonic stem cells. | PloS one 20120101 |
| Current approaches toward production of secondary plant metabolites. | Journal of pharmacy & bioallied sciences 20120101 |
| Stilbene derivatives promote Ago2-dependent tumour-suppressive microRNA activity. | Scientific reports 20120101 |
| How morphological constraints affect axonal polarity in mouse neurons. | PloS one 20120101 |
| Anogenital squamous cell carcinoma in neglected patient. | Bratislavske lekarske listy 20120101 |
| Inhibition mechanism and model of an angiotensin I-converting enzyme (ACE)-inhibitory hexapeptide from yeast (Saccharomyces cerevisiae). | PloS one 20120101 |
| Modified carbon nanotube paste electrode for voltammetric determination of carbidopa, folic Acid, and tryptophan. | Journal of analytical methods in chemistry 20120101 |
| Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II. | Biochemical pharmacology 20111215 |
| Carbamates of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxicity and cell cycle effects. | Bioorganic & medicinal chemistry letters 20111215 |
| Bis(oxyphenylene)benzimidazoles: a novel class of anti-Plasmodium falciparum agents. | Bioorganic & medicinal chemistry 20111215 |
| Design and synthesis of N-phosphoryl peptide modified podophyllotoxin derivatives as potent anticancer agents. | Protein and peptide letters 20111201 |
| Absolute configuration of podophyllotoxin related lignans from Bursera fagaroides using vibrational circular dichroism. | Phytochemistry 20111201 |
| Identification of lignans and related compounds in Anthriscus sylvestris by LC-ESI-MS/MS and LC-SPE-NMR. | Phytochemistry 20111201 |
| Facile synthesis of new 4-aza-podophyllotoxin analogs via microwave-assisted multi-component reactions and evaluation of their cytotoxic activity. | Bioorganic & medicinal chemistry letters 20111201 |
| Inhibition of CYP3A4 and CYP2C9 by podophyllotoxin: implication for clinical drug-drug interactions. | Journal of biosciences 20111201 |
| Stress-mediated adaptive response leading to genetic diversity and instability in metabolite contents of high medicinal value: an overview on Podophyllum hexandrum. | Omics : a journal of integrative biology 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Synthesis and cytotoxicity evaluation of novel podophyllotoxin derivatives. | Archiv der Pharmazie 20111101 |
| Biological evaluation of glycosyl-isoindigo derivatives against the pathogenic agents of tropical diseases (malaria, Chagas disease, leishmaniasis and human African trypanosomiasis). | Bioorganic & medicinal chemistry letters 20111101 |
| [Molecular determinants of response to topoisomerase II inhibitors]. | Bulletin du cancer 20111101 |
| 9-{[4-(Dimethyl-amino)-benzyl]amino}-5-(4-hy-droxy-3,5-dimeth-oxy-phenyl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one methanol monosolvate. | Acta crystallographica. Section E, Structure reports online 20111101 |
| In vitro antiprotozoal activity of extracts of five Turkish Lamiaceae species. | Natural product communications 20111101 |
| Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species. | The Journal of biological chemistry 20111028 |
| Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays. | Journal of medicinal chemistry 20111027 |
| 5k, a novel β-O-demethyl-epipodophyllotoxin analogue, inhibits the proliferation of cancer cells in vitro and in vivo via the induction of G2 arrest and apoptosis. | Investigational new drugs 20111001 |
| Genital warts and cost of care in England. | Sexually transmitted infections 20111001 |
| Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a]phenoxazine derivatives. | Bioorganic & medicinal chemistry letters 20111001 |
| [Anti-MDR tumor mechanism of CIP-36, a podophyllotoxin derivative]. | Yao xue xue bao = Acta pharmaceutica Sinica 20111001 |
| Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum. | Journal of natural products 20110923 |
| N-hydroxyethyl-4-aza-didehydropodophyllotoxin derivatives as potential antitumor agents. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110918 |
| Natural products-based insecticidal agents 11. Synthesis and insecticidal activity of novel 4α-arylsulfonyloxybenzyloxy-2β-chloropodophyllotoxin derivatives against Mythimna separata Walker in vivo. | Bioorganic & medicinal chemistry letters 20110915 |
| Podophyllotoxin and other aryltetralin lignans from Eriope latifolia and Eriope blanchetii. | Natural product research 20110901 |
| Podophyllotoxin-derived insecticidal agents: part XIII--evaluation of insecticidal activity of podophyllotoxin derivatives against Brontispa longissima. | Natural product research 20110901 |
| Synthesis and biological evaluation of derivatives of 4-deoxypodophyllotoxin as antitumor agents. | European journal of medicinal chemistry 20110901 |
| Anticancer lignans--from discovery to biotechnology. | Mini reviews in medicinal chemistry 20110901 |
| Recent advances in semisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: an update (2008-2010). | Mini reviews in medicinal chemistry 20110901 |
| Synthesis of 4β-triazole-podophyllotoxin derivatives by azide-alkyne cycloaddition and biological evaluation as potential antitumor agents. | European journal of medicinal chemistry 20110901 |
| Seasonal variations in the deoxypodophyllotoxin content and yield of Anthriscus sylvestris L. (Hoffm.) grown in the field and under controlled conditions. | Journal of agricultural and food chemistry 20110810 |
| Podophyllotoxin and deoxypodophyllotoxin in Juniperus bermudiana and 12 other Juniperus species: optimization of extraction, method validation, and quantification. | Journal of agricultural and food chemistry 20110810 |
| Association of HSV reactivation and pro-inflammatory cytokine levels with the severity of stomatitis after BEAM chemotherapy and autologous SCT. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110801 |
| Antiplasmodial and cytotoxicity evaluation of 3-functionalized 2-azetidinone derivatives. | Bioorganic & medicinal chemistry letters 20110801 |
| Synthesis and biological evaluation of 4β-acrylamidopodophyllotoxin congeners as DNA damaging agents. | Bioorganic & medicinal chemistry 20110801 |
| Does immunotherapy of viral warts provide beneficial effects when it is combined with conventional therapy? | Annals of dermatology 20110801 |
| 9-[(Furan-2-ylmeth-yl)amino]-5-(3,4,5-trimeth-oxy-phen-yl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one. | Acta crystallographica. Section E, Structure reports online 20110801 |
| Stereoselective synthesis of 4α-alkyloxy-2-α/β-bromopodophyllotoxin derivatives as insecticidal agents. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110718 |
| Phenylimino-10H-anthracen-9-ones as novel antimicrotubule agents-synthesis, antiproliferative activity and inhibition of tubulin polymerization. | Bioorganic & medicinal chemistry 20110715 |
| Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4. | Journal of medicinal chemistry 20110714 |
| Antimalarial pyrido[1,2-a]benzimidazoles. | Journal of medicinal chemistry 20110714 |
| Unexpectedly convenient and stereoselective synthesis of 4α-acyloxy-2-chloropodophyllotoxins in the presence of BF₃ ·Et₂O. | Bioorganic & medicinal chemistry letters 20110701 |
| N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20110623 |
| Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis. | Journal of medicinal chemistry 20110623 |
| Three new cytotoxic aryltetralin lignans from Sinopodophyllum emodi. | Bioorganic & medicinal chemistry letters 20110615 |
| Development and characterization of molecularly imprinted polymers for the selective enrichment of podophyllotoxin from traditional Chinese medicines. | Analytica chimica acta 20110610 |
| Application of ionic liquids in the microwave-assisted extraction of podophyllotoxin from Chinese herbal medicine. | The Analyst 20110607 |
| Expression and effects of inhibition of type I insulin-like growth factor receptor tyrosine kinase in mantle cell lymphoma. | Haematologica 20110601 |
| 4β-[(4-Alkyl)-1,2,3-triazol-1-yl] podophyllotoxins as anticancer compounds: design, synthesis and biological evaluation. | European journal of medicinal chemistry 20110601 |
| 9-[(2-Chloro-benz-yl)amino]-5-(3,4,5-trimeth-oxy-phen-yl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one. | Acta crystallographica. Section E, Structure reports online 20110601 |
| 9-{[4-(Dimethyl-amino)-benz-yl]amino}-5-(3,4,5-trimeth-oxy-phen-yl)-5,5a,8a,9-tetra-hydro-furo[3',4':6,7]naphtho-[2,3-d][1,3]dioxol-6(8H)-one. | Acta crystallographica. Section E, Structure reports online 20110601 |
| Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents. | Bioorganic & medicinal chemistry 20110501 |
| Synthesis and antitumor activity of novel podophyllotoxin derivatives against multidrug-resistant cancer cells. | Journal of Asian natural products research 20110501 |
| Genetic reconstruction of protozoan rRNA decoding sites provides a rationale for paromomycin activity against Leishmania and Trypanosoma. | PLoS neglected tropical diseases 20110501 |
| [Resources of survey in rare and endangered medicinal plant Sinopodophyllum emodi]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110501 |
| [Review on biosynthesis of podophyllotoxin]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110501 |
| Involvement of P-glycoprotein and CYP 3A4 in the enhancement of etoposide bioavailability by a piperine analogue. | Chemico-biological interactions 20110425 |
| Didemnidines A and B, indole spermidine alkaloids from the New Zealand ascidian Didemnum sp. | Journal of natural products 20110425 |
| Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. | Journal of natural products 20110425 |
| Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavage. | Biochemistry 20110419 |
| A synthetic route to highly substituted 1,2,3,4-tetrahydroisoquinolines via Yb(OTf)3 -catalyzed diastereoselective ring opening of bridged oxazolidines: asymmetric synthesis of 2-azapodophyllotoxin. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110418 |
| Peripheral sensitization caused by insulin-like growth factor 1 contributes to pain hypersensitivity after tissue injury. | Pain 20110401 |
| Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents. | Bioorganic & medicinal chemistry 20110401 |
| β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. | Bioorganic & medicinal chemistry 20110401 |
| (90)Y ibritumomab tiuxetan (Zevalin) combined with BEAM (Z -BEAM) conditioning regimen plus autologous stem cell transplantation in relapsed or refractory low-grade CD20-positive B-cell lymphoma. A GELA phase II prospective study. | Clinical lymphoma, myeloma & leukemia 20110401 |
| Efficacy and safety of imiquimod versus podophyllotoxin in the treatment of anogenital warts. | Sexually transmitted diseases 20110301 |
| Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors. | European journal of medicinal chemistry 20110301 |
| Immunobiological properties of selected natural and chemically modified phenylpropanoids. | Interdisciplinary toxicology 20110301 |
| Determination of picropodophyllin and its isomer podophyllotoxin in human serum samples with electrospray ionization of hexylamine adducts by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110215 |
| Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system. | Investigational new drugs 20110201 |
| A novel bis-indole destabilizes microtubules and displays potent in vitro and in vivo antitumor activity in prostate cancer. | Cancer chemotherapy and pharmacology 20110201 |
| Plant-derived bioactive compounds produced by endophytic fungi. | Mini reviews in medicinal chemistry 20110201 |
| Deoxypodophyllotoxin Induces a Th1 Response and Enhances the Antitumor Efficacy of a Dendritic Cell-based Vaccine. | Immune network 20110201 |
| Role of the adrenergic system in a mouse model of oxygen-induced retinopathy: antiangiogenic effects of beta-adrenoreceptor blockade. | Investigative ophthalmology & visual science 20110105 |
| Podophyllum hexandrum-Mediated Survival Protection and Restoration of Other Cellular Injuries in Lethally Irradiated Mice. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Andrographolide: a new plant-derived antineoplastic entity on horizon. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| REC-2006-A Fractionated Extract of Podophyllum hexandrum Protects Cellular DNA from Radiation-Induced Damage by Reducing the Initial Damage and Enhancing Its Repair In Vivo. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Chemometric evaluation of the anti-cancer pro-drug podophyllotoxin and potential therapeutic analogues in Juniperus and Podophyllum species. | Phytochemical analysis : PCA 20110101 |
| Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation. | Bioorganic & medicinal chemistry 20110101 |
| An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity. | Bioorganic & medicinal chemistry letters 20110101 |
| Synthesis and biological evaluation of new 4β-anilino-4'-O-demethyl-4-desoxypodophyllotoxin derivatives as potential antitumor agents. | European journal of medicinal chemistry 20110101 |
| Antimicrobial topical agents used in the vagina. | Current problems in dermatology 20110101 |
| The use of endophytes to obtain bioactive compounds and their application in biotransformation process. | Biotechnology research international 20110101 |
| Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP). | PloS one 20110101 |
| Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells. | Molecular cancer 20110101 |
| Molecular characterization of Chinese hamster cells mutants affected in adenosine kinase and showing novel genetic and biochemical characteristics. | BMC biochemistry 20110101 |
| Antiproliferation and cell apoptosis inducing bioactivities of constituents from Dysosma versipellis in PC3 and Bcap-37 cell lines. | Cell division 20110101 |
| Toxicity and neuropharmacological effects of elenine. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Apoptotic mechanism of human leukemia K562/A02 cells induced by magnetic iron oxide nanoparticles co-loaded with daunorubicin and 5-bromotetrandrin. | International journal of nanomedicine 20110101 |
| Antiprotozoal activities of organic extracts from French marine seaweeds. | Marine drugs 20110101 |
| Role of Apoptotic Proteins in REC-2006 Mediated Radiation Protection in Hepatoma Cell Lines. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
| Synthetic and application perspectives of azapodophyllotoxins: alternative scaffolds of podophyllotoxin. | Current medicinal chemistry 20110101 |
| An integrated Drosophila model system reveals unique properties for F14512, a novel polyamine-containing anticancer drug that targets topoisomerase II. | PloS one 20110101 |
| Imiquimod 3.75% cream applied daily to treat anogenital warts: combined results from women in two randomized, placebo-controlled studies. | Infectious diseases in obstetrics and gynecology 20110101 |
| Assessment of anti-cytogenotoxic effects of quercetin in animals treated with topotecan. | Oxidative medicine and cellular longevity 20110101 |
| Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells. | PloS one 20110101 |
| Microwave-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait. | International journal of molecular sciences 20110101 |
| CCND1 as a predictive biomarker of neoadjuvant chemotherapy in patients with locally advanced head and neck squamous cell carcinoma. | PloS one 20110101 |
| Reduction of atherosclerotic lesions in rabbits treated with etoposide associated with cholesterol-rich nanoemulsions. | International journal of nanomedicine 20110101 |
| Darinaparsin is a multivalent chemotherapeutic which induces incomplete stress response with disruption of microtubules and Shh signaling. | PloS one 20110101 |
| Identification of cytotoxic drugs that selectively target tumor cells with MYC overexpression. | PloS one 20110101 |
| The integrated HIV-1 provirus in patient sperm chromosome and its transfer into the early embryo by fertilization. | PloS one 20110101 |
| [Comparative assessment of the methods of treatment of Condylomata acuminata]. | Akusherstvo i ginekologiia 20110101 |
| Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities. | Bioorganic & medicinal chemistry 20101215 |
| Design, synthesis, and biological evaluation of the first podophyllotoxin analogues as potential vascular-disrupting agents. | ChemMedChem 20101203 |
| Role of radiation dose in the risk of secondary leukemia after a solid tumor in childhood treated between 1980 and 1999. | International journal of radiation oncology, biology, physics 20101201 |
| Pharmacological effect of deoxypodophyllotoxin: a medicinal agent of plant origin, on mammalian neurons. | Neurotoxicology 20101201 |
| Optimization of podophyllotoxin extraction method from Linum album cell cultures. | Pharmaceutical biology 20101201 |
| Development of predictive quantitative structure-activity relationship models of epipodophyllotoxin derivatives. | Journal of biomolecular screening 20101201 |
| The binding modes and binding affinities of epipodophyllotoxin derivatives with human topoisomerase IIα. | Journal of molecular graphics & modelling 20101201 |
| Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway. | The Journal of biological chemistry 20101126 |
| Salicylic acid improves podophyllotoxin production in cell cultures of Linum album by increasing the expression of genes related with its biosynthesis. | Biotechnology letters 20101101 |
| Synthesis and cytotoxicity evaluation of novel 1,4-disubstituted 1,2,3-triazoles via CuI catalysed 1,3-dipolar cycloaddition. | European journal of medicinal chemistry 20101101 |
| QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids. | European journal of medicinal chemistry 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| 2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections. | Bioorganic & medicinal chemistry 20101101 |
| A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment. | Leukemia research 20101001 |
| Structure-based virtual screening of novel tubulin inhibitors and their characterization as anti-mitotic agents. | Bioorganic & medicinal chemistry 20101001 |
| Competitive mass spectrometry binding assay for characterization of three binding sites of tubulin. | Journal of mass spectrometry : JMS 20101001 |
| [Topical imiquimod for the treatment of anogenital warts in an infant]. | Annales de dermatologie et de venereologie 20101001 |
| [Effect of deoxypodophyllotoxin on membrane potential of dorsal unpaired median neurons and its relationship with sodium channel]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20101001 |
| IGF-1 receptor inhibition by picropodophyllin in medulloblastoma. | Biochemical and biophysical research communications 20100903 |
| Natural products-based insecticidal agents 7. Semisynthesis and insecticidal activity of novel 4alpha-alkyloxy-2-chloropodophyllotoxin derivatives against Mythimna separata Walker in vivo. | Bioorganic & medicinal chemistry letters 20100901 |
| Drug-induced regulation of target expression. | PLoS computational biology 20100901 |
| Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium. | Journal of natural products 20100827 |
| Immunomagnetic selection of CD34(+) cells carried out in cryopreserved cell concentrates from a paediatric patient affected with non-Hodgkin lymphoma. | Transfusion medicine (Oxford, England) 20100801 |
| Synthesis, antiproliferative activity and inhibition of tubulin polymerization by 1,5- and 1,8-disubstituted 10H-anthracen-9-ones bearing a 10-benzylidene or 10-(2-oxo-2-phenylethylidene) moiety. | European journal of medicinal chemistry 20100801 |
| Natural products-based insecticidal agents 6. Design, semisynthesis, and insecticidal activity of novel monomethyl phthalate derivatives of podophyllotoxin against Mythimna separata Walker in vivo. | Bioorganic & medicinal chemistry letters 20100801 |
| Podophyllotoxin derivatives show activity against Brontispa longissima larvae. | Natural product communications 20100801 |
| Disruption of IGF-1R signaling increases TRAIL-induced apoptosis: a new potential therapy for the treatment of melanoma. | Experimental cell research 20100715 |
| Regioselective synthesis and in vitro anticancer activity of 4-aza-podophyllotoxin derivatives catalyzed by L-proline. | Journal of combinatorial chemistry 20100712 |
| Molecular characterization and marker based chemotaxonomic studies of Podophyllum hexandrum Royle. | Fitoterapia 20100601 |
| Molecular modeling and structure-activity relationship of podophyllotoxin and its congeners. | Journal of biomolecular screening 20100601 |
| Pegfilgrastim appears equivalent to daily dosing of filgrastim to treat neutropenia after autologous peripheral blood stem cell transplantation in patients with non-Hodgkin lymphoma. | Clinical lymphoma, myeloma & leukemia 20100601 |
| [Quantitative determination of podophyllotoxin in dermal and blood microdialysis samples of rats by liquid chromatography-tandem mass spectrometry]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100601 |
| Selective insulin-like growth factor-I antagonist inhibits mouse embryo development in a dose-dependent manner. | Fertility and sterility 20100515 |
| Inhibitory effects of deoxypodophyllotoxin from Anthriscus sylvestris on human CYP2C9 and CYP3A4. | Planta medica 20100501 |
| 6-methoxypodophyllotoxin-7-O-n-hexanoate, a new aryltetralin lignan ester from seeds of Linum flavum. | Planta medica 20100501 |
| Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays. | European journal of medicinal chemistry 20100501 |
| Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of beta-catenin signaling. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100501 |
| Search for new and novel chemotherapeutics for the treatment of human malignancies. | Mini reviews in medicinal chemistry 20100501 |
| Jacaranone-derived glucosidic esters from Jacaranda glabra and their activity against Plasmodium falciparum. | Journal of natural products 20100423 |
| Insulin-like growth factor-I receptor in proliferation and motility of pancreatic cancer. | World journal of gastroenterology 20100421 |
| Natural products-based insecticidal agents 5. Design, semisynthesis and insecticidal activity of novel 4'-substituted benzenesulfonate derivatives of 4-deoxypodophyllotoxin against Mythimna separata Walker in vivo. | Bioorganic & medicinal chemistry letters 20100415 |
| 5-FU for genital warts in non-immunocompromised individuals. | The Cochrane database of systematic reviews 20100414 |
| Characterization of the colchicine binding site on avian tubulin isotype betaVI. | Biochemistry 20100406 |
| First synthesis and biological evaluation of novel spin-labeled derivatives of deoxypodophyllotoxin. | European journal of medicinal chemistry 20100401 |
| Cytotoxicity and apoptosis induced by a new podophyllotoxin glucoside in human hepatoma (HepG2) cells. | Canadian journal of physiology and pharmacology 20100401 |
| Comparison of the cytotoxic effects of Juniperus sabina and Zataria multiflora extracts with Taxus baccata extract and Cisplatin on normal and cancer cell lines. | Pharmacognosy magazine 20100401 |
| The in vitro and in vivo anti-tumor effect of layered double hydroxides nanoparticles as delivery for podophyllotoxin. | International journal of pharmaceutics 20100330 |
| Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach. | Journal of natural products 20100326 |
| Discovery of novel and potent benzhydryl-tropane trypanocides highly selective for Trypanosoma cruzi. | Bioorganic & medicinal chemistry letters 20100315 |
| Updated biotechnological approaches developed for 2,7'-cyclolignan production1. | Biotechnology and applied biochemistry 20100312 |
| Podophyllotoxin analogues active versus Trypanosoma brucei. | Bioorganic & medicinal chemistry letters 20100301 |
| A QSAR study on the cytotoxicity of podophyllotoxin analogues against various cancer cell lines. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20100301 |
| Antiproliferative cardenolides from Pentopetia androsaemifolia Decne. from the Madagascar rain forest. | Indian journal of experimental biology 20100301 |
| 6-{[(Benz-yloxy)carbon-yl]-oxy}-2-methyl-hexa-hydro-pyrano[3,2-d][1,3]dioxin-7,8-diyl bis-(chloro-acetate). | Acta crystallographica. Section E, Structure reports online 20100301 |
| 7-p-Tolyl-10,11-dihydro-benzo[h]furo[3,4-b]quinolin-8(7H)-one. | Acta crystallographica. Section E, Structure reports online 20100301 |
| Podophyllum hexandrum as a potential botanical supplement for the medical management of nuclear and radiological emergencies (NREs) and free radical-mediated ailments: leads from in vitro/in vivo radioprotective efficacy evaluation. | Journal of dietary supplements 20100301 |
| Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives. | Journal of medicinal chemistry 20100211 |
| Synthesis and biological evaluation of new podophyllic aldehyde derivatives with cytotoxic and apoptosis-inducing activities. | Journal of medicinal chemistry 20100211 |
| A novel podophyllotoxin derivative (YB-1EPN) induces apoptosis and down-regulates express of P-glycoprotein in multidrug resistance cell line KBV200. | European journal of pharmacology 20100210 |
| A novel biotransformation process of 4'-demethylepipodophyllotoxin to 4'-demethylepipodophyllic acid by Bacillus fusiformis CICC 20463, Part II: process optimization. | Bioprocess and biosystems engineering 20100201 |
| Tuned C-H functionalization to construct aza-podophyllotoxin/aza-conidendrin derivatives by means of domino cyclization. | Chemistry, an Asian journal 20100201 |
| Novel semisynthetic spin-labeled derivatives of podophyllotoxin with cytotoxic and antioxidative activity. | Bioorganic & medicinal chemistry letters 20100201 |
| Novel 4 beta-anilino-podophyllotoxin derivatives: design synthesis and biological evaluation as potent DNA-topoisomerase II poisons and anti-MDR agents. | Molecular bioSystems 20100201 |
| Consensus conference on the use of 90-yttrium-ibritumomab tiuxetan therapy in clinical practice. A project of the Italian society of hematology. | American journal of hematology 20100201 |
| Design and synthesis of C-ring lactone- and lactam-based podophyllotoxin analogues as anticancer agents. | Chemical & pharmaceutical bulletin 20100201 |
| Reversal of mdr1-mediated multidrug resistance in human leukemia cells by a new spin-labeled derivative of podophyllotoxin. | Die Pharmazie 20100201 |
| Design, synthesis and biological evaluation of novel spin-labeled derivatives of podophyllotoxin. | Natural product communications 20100201 |
| [Comparison of the biodistribution and PET imaging with (11)C-PDT and (18)F-FDG in the mouse model of lung adenocarcinoma]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100201 |
| Deoxypodophyllotoxin induces G2/M cell cycle arrest and apoptosis in HeLa cells. | Cancer letters 20100128 |
| Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles. | Journal of medicinal chemistry 20100114 |
| A facile construction strategy of stable lipid nanoparticles for drug delivery using a hydrogel-thickened microemulsion system. | Nanotechnology 20100108 |
| Synthesis and biological evaluation of novel thiocolchicine-podophyllotoxin conjugates. | European journal of medicinal chemistry 20100101 |
| Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. | Bioorganic & medicinal chemistry 20100101 |
| Verteporfin photodynamic therapy of retinal capillary hemangioblastoma in von Hippel-Lindau disease. | Indian journal of ophthalmology 20100101 |
| Podophyllotoxin induces CREB phosphorylation and CRE-driven gene expression via PKA but not MAPKs. | Molecules and cells 20100101 |
| Deoxypodophyllotoxin inhibits the expression of intercellular adhesion molecule-1 induced by tumor necrosis factor-alpha in murine lung epithelial cells. | Biological & pharmaceutical bulletin 20100101 |
| Molecular bases of liver cancer refractoriness to pharmacological treatment. | Current medicinal chemistry 20100101 |
| Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma. | Neuro-oncology 20100101 |
| Inhibitory activity of marine sponge-derived natural products against parasitic protozoa. | Marine drugs 20100101 |
| The quality of life of patients with genital warts: a qualitative study. | BMC public health 20100101 |
| The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate c-myc target genes in mammalian tumor cells. | PloS one 20100101 |
| Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells. | BMC cancer 20100101 |
| A novel synthetic analog of 5, 8-disubstituted quinazolines blocks mitosis and induces apoptosis of tumor cells by inhibiting microtubule polymerization. | PloS one 20100101 |
| Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine. | BMC cancer 20100101 |
| A screen for kinetochore-microtubule interaction inhibitors identifies novel antitubulin compounds. | PloS one 20100101 |
| Bromopyrrole alkaloids as lead compounds against protozoan parasites. | Marine drugs 20100101 |
| Sustained spindle-assembly checkpoint response requires de novo transcription and translation of cyclin B1. | PloS one 20100101 |
| Production of podophyllotoxin in Linum linearifolium in vitro cultures. | Pharmacognosy magazine 20100101 |
| Equivalence of pegfilgrastim and filgrastim in lymphoma patients treated with BEAM followed by autologous stem cell transplantation. | Oncology 20100101 |
| Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. | Journal of ethnobiology and ethnomedicine 20100101 |
| Quick and simple detection technique to assess the binding of antimicrotubule agents to the colchicine-binding site. | Biological procedures online 20100101 |
| Warts (genital). | BMJ clinical evidence 20100101 |
| Anticancer drugs from marine flora: an overview. | Journal of oncology 20100101 |
| Medical radiation countermeasures for nuclear and radiological emergencies: Current status and future perspectives. | Journal of pharmacy & bioallied sciences 20100101 |
| Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs. | Pharmacognosy reviews 20100101 |
| A multicentre, randomised, double-blind, placebo controlled study of cryotherapy versus cryotherapy and podophyllotoxin cream as treatment for external anogenital warts. | Sexually transmitted infections 20091201 |
| Abnormal blood vessels formed by human liver cavernous hemangioma endothelial cells in nude mice are suitable for drug evaluation. | Microvascular research 20091201 |
| Apoptosis of human Burkitt's lymphoma cells induced by 2-N,N-diethylaminocarbonyloxymethyl-1-diphenylmethyl-4-(3,4,5-trimethoxybenzoyl) piperazine hydrochloride (PMS-1077). | Archives of pharmacal research 20091201 |
| 4-Des-oxy-4β-(4-methoxy-carbonyl-1,2,3-triazol-1-yl)podophyllotoxin dichloro-methane solvate. | Acta crystallographica. Section E, Structure reports online 20091201 |
| Combretastatin-like chalcones as inhibitors of microtubule polymerisation. Part 2: Structure-based discovery of alpha-aryl chalcones. | Bioorganic & medicinal chemistry 20091115 |
| Anticancer agents derived from natural products. | Mini reviews in medicinal chemistry 20091101 |
| Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues. | Bioorganic & medicinal chemistry 20091015 |
| Prognostic factors for the response to treatment in males with genital warts. | Journal of the European Academy of Dermatology and Venereology : JEADV 20091001 |
| Imiquimod 5% cream for external genital or perianal warts in human immunodeficiency virus-positive patients treated with highly active antiretroviral therapy: an open-label, noncomparative study. | The British journal of dermatology 20091001 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Phase II study of combination chemotherapy with etoposide and ifosfamide in patients with heavily pretreated recurrent or persistent epithelial ovarian cancer. | Journal of Korean medical science 20091001 |
| Natural products-based insecticidal agents 4. Semisynthesis and insecticidal activity of novel esters of 2-chloropodophyllotoxin against Mythimna separata Walker in vivo. | Bioorganic & medicinal chemistry letters 20090915 |
| Semisynthesis and quantitative structure-activity relationship (QSAR) study of novel aromatic esters of 4'-demethyl-4-deoxypodophyllotoxin as insecticidal agents. | Journal of agricultural and food chemistry 20090909 |
| Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes. | European journal of medicinal chemistry 20090901 |
| Aspergillus fumigatus Fresenius, an endophytic fungus from Juniperus communis L. Horstmann as a novel source of the anticancer pro-drug deoxypodophyllotoxin. | Journal of applied microbiology 20090901 |
| Podophyllum hexandrum fraction (REC-2006) shows higher radioprotective efficacy in the p53-carrying hepatoma cell line: a role of cell cycle regulatory proteins. | Integrative cancer therapies 20090901 |
| The influence of bioactive oxylipins from marine diatoms on invertebrate reproduction and development. | Marine drugs 20090901 |
| Beta-amyloid monomers are neuroprotective. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826 |
| Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine. | Journal of medicinal chemistry 20090813 |
| Novel biotransformation process of podophyllotoxin to produce podophyllic acid and picropodophyllotoxin by Pseudomonas aeruginosa CCTCC AB93066. Part I: process development. | Bioprocess and biosystems engineering 20090801 |
| Antitumor activity of deoxypodophyllotoxin isolated from Anthriscus sylvestris: Induction of G2/M cell cycle arrest and caspase-dependent apoptosis. | Bioorganic & medicinal chemistry letters 20090801 |
| pY-STAT3 and p53 expression predict outcome for poor prognosis diffuse large B-cell lymphoma treated with high dose chemotherapy and autologous stem cell transplantation. | Leukemia & lymphoma 20090801 |
| Giant condyloma with demise secondary to meningococcemia in an infant boy. | Journal of pediatric urology 20090801 |
| Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines. | Molecular cancer therapeutics 20090801 |
| Deoxypodophyllotoxin, flavolignan, from Anthriscus sylvestris Hoffm. inhibits migration and MMP-9 via MAPK pathways in TNF-alpha-induced HASMC. | Vascular pharmacology 20090701 |
| The management of condyloma acuminata in the pediatric population. | Pediatric annals 20090701 |
| Insecticidal heterolignans--tubuline polymerization inhibitors with activity against chewing pests. | Bioorganic & medicinal chemistry 20090615 |
| Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase. | Bioorganic & medicinal chemistry letters 20090601 |
| Conditional drug screening shows that mitotic inhibitors induce AKT/PKB-insensitive apoptosis. | Journal of chemical biology 20090601 |
| Synthesis and antiparasitic and antifungal evaluation of 2'-arylsubstituted-1H,1'H-[2,5']bisbenzimidazolyl-5-carboxamidines. | European journal of medicinal chemistry 20090501 |
| HPLC-DAD and HPLC-ESI-MS separation, determination and identification of the spin-labeled diastereoisomers of podophyllotoxin. | Journal of separation science 20090501 |
| [Stem cell therapy in multiple sclerosis: a clinical update]. | Zeitschrift fur Rheumatologie 20090501 |
| Synthesis and biological evaluation of novel conjugates of podophyllotoxin and 5-FU as antineoplastic agents. | Bioorganic & medicinal chemistry 20090415 |
| Structure-activity study of pentamidine analogues as antiprotozoal agents. | Journal of medicinal chemistry 20090409 |
| Molecular modelling evaluation of the cytotoxic activity of podophyllotoxin analogues. | Journal of computer-aided molecular design 20090401 |
| Novel biotransformation process of podophyllotoxin to produce podophyllic acid and picropodophyllotoxin by Pseudomonas aeruginosa CCTCC AB93066, part II: process optimization. | Bioresource technology 20090401 |
| Yttrium-90 ibritumomab tiuxetan doses calculated to deliver up to 15 Gy to critical organs may be safely combined with high-dose BEAM and autologous transplantation in relapsed or refractory B-cell non-Hodgkin's lymphoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090401 |
| L1EPO, a novel podophyllotoxin derivative overcomes P-glycoprotein-mediated multidrug resistance in K562/A02 cell line. | Biological & pharmaceutical bulletin 20090401 |
| Germinating seeds of the mung bean, Vigna radiata (Fabaceae), as a model for the preliminary evaluation of cytotoxic effects of drugs. | Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20090401 |
| [Genital warts]. | Praxis 20090318 |
| 10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20090312 |
| Green tea catechins for treatment of external genital warts. | American journal of obstetrics and gynecology 20090301 |
| Diagnosis and management of hypersensitivity reactions related to common cancer chemotherapy agents. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090301 |
| Effects of zearalenone and alpha-Zearalenol in comparison with Raloxifene on T47D cells. | Toxicology mechanisms and methods 20090301 |
| Enantioselective sequential conjugate addition-allylation reactions: a concise total synthesis of (+)-podophyllotoxin. | Organic letters 20090205 |
| Preparation, characterization, and anti-tumor property of podophyllotoxin-loaded solid lipid nanoparticles. | Nanotechnology 20090204 |
| Antiplasmodial and antitrypanosomal activities of aminobicyclo[2.2.2]octyl omega-aminoalkanoates. | European journal of medicinal chemistry 20090201 |
| Redox-active dinitrodiphenylthioethers against Leishmania: synthesis, structure-activity relationships and mechanism of action studies. | Bioorganic & medicinal chemistry 20090115 |
| Comparison of podophyllotoxin and imiquimod as anal condyloma acuminata therapy. | Dermatology online journal 20090115 |
| Acute leukemia as a secondary malignancy in children and adolescents: current findings and issues. | Cancer 20090101 |
| A review on hemisynthesis, biosynthesis, biological activities, mode of action, and structure-activity relationship of podophyllotoxins: 2003-2007. | Current medicinal chemistry 20090101 |
| Applying linear interaction energy method for binding affinity calculations of podophyllotoxin analogues with tubulin using continuum solvent model and prediction of cytotoxic activity. | Journal of molecular graphics & modelling 20090101 |
| [Adverse muscle effects of a podofyllotoxin-containing cytotoxic drug product with simvastatin]. | Duodecim; laaketieteellinen aikakauskirja 20090101 |
| Podophyllin, but not the constituents quercetin or kaempferol, induced genotoxicity in vitro and in vivo through ROS production. | Drug and chemical toxicology 20090101 |
| The role of biotechnology in the production of the anticancer compound podophyllotoxin. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| Small-cell prostate carcinoma: A retrospective analysis of five newly reported cases. | Indian journal of urology : IJU : journal of the Urological Society of India 20090101 |
| Interferon for the treatment of genital warts: a systematic review. | BMC infectious diseases 20090101 |
| Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transporters. | PloS one 20090101 |
| Sexually transmitted papillomavirus infections: epidemiology pathogenesis, clinic, morphology, important differential diagnostic aspects, current diagnostic and treatment options. | Anais brasileiros de dermatologia 20090101 |
| Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening. | PloS one 20090101 |
| 7-Methyl-9-p-tolyl-4,9-dihydro-furo[3,4-b]quinolin-1(3H)-one. | Acta crystallographica. Section E, Structure reports online 20090101 |
| Selection methodology with scoring system: application to Mexican plants producing podophyllotoxin related lignans. | Journal of ethnopharmacology 20081208 |
| Effect of aeration on production of anticancer lignans by cell suspension cultures of Linum album. | Applied biochemistry and biotechnology 20081201 |
| F14512, a potent antitumor agent targeting topoisomerase II vectored into cancer cells via the polyamine transport system. | Cancer research 20081201 |
| Uveal melanoma and macular degeneration: molecular biology and potential therapeutic applications. | Acta ophthalmologica 20081201 |
| 4-Des-oxy-4β-[(5-meth-oxy-1H-indol-3-yl)oxalylamino]podophyllotoxin methanol solvate. | Acta crystallographica. Section E, Structure reports online 20081201 |
| Separation, determination and identification of the diastereoisomers of podophyllotoxin and its esters by high-performance liquid chromatography/tandem mass spectrometry. | Journal of chromatography. A 20081114 |
| Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans. | Journal of medicinal chemistry 20081113 |
| Anal intraepithelial neoplasia in HIV infection. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20081101 |
| Introduction: Uveal melanoma. | Acta ophthalmologica 20081101 |
| The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells. | Acta ophthalmologica 20081101 |
| Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma. | Acta ophthalmologica 20081101 |
| Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor. | Acta ophthalmologica 20081101 |
| Studies on novel 4beta-[(4-substituted)-1,2,3-triazol-1-yl] podophyllotoxins as potential anticancer agents. | European journal of medicinal chemistry 20081001 |
| Improved podophyllotoxin production by transformed cultures of Linum album. | Biotechnology journal 20081001 |
| Synthesis and structure-activity relationship of 3-phenylquinoxaline 1,4-di-N-oxide derivatives as antimalarial agents. | European journal of medicinal chemistry 20080901 |
| Co-culture of arbuscular mycorrhiza-like fungi (Piriformospora indica and Sebacina vermifera) with plant cells of Linum album for enhanced production of podophyllotoxins: a first report. | Biotechnology letters 20080901 |
| Keratinocyte growth factor is effective in the prevention of intestinal mucositis in patients with hematological malignancies treated with high-dose chemotherapy and autologous hematopoietic SCT: a video-capsule endoscopy study. | Bone marrow transplantation 20080901 |
| Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus Chaetomium sp. | Journal of natural products 20080901 |
| Modulation of gamma radiation-inflicted damage in Swiss albino mice by an alcoholic fraction of Podophyllum hexandrum rhizome. | Journal of medicinal food 20080901 |
| Synthesis and biological evaluation of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxins as potential anticancer agents. | Chemistry & biodiversity 20080901 |
| Structure-activity relationship studies on a novel class of antiproliferative agents derived from Lavendustin A. Part I: Ring A modifications. | Bioorganic & medicinal chemistry 20080815 |
| Noninvasive real-time imaging of intima thickness after rat carotid artery balloon injury using ultrasound biomicroscopy. | Atherosclerosis 20080801 |
| New picropodophyllin analogs via palladium-catalyzed allylic alkylation-Hiyama cross-coupling sequences. | The Journal of organic chemistry 20080801 |
| Treatments for genital warts. | Journal of drugs in dermatology : JDD 20080801 |
| [Effect of podophyllotoxin on human gastric cancer cell line SGC 7901]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080801 |
| Gallic acid-based indanone derivatives as anticancer agents. | Bioorganic & medicinal chemistry letters 20080715 |
| Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis. | Hepatology (Baltimore, Md.) 20080701 |
| Comorbidities, not age, impact outcomes in autologous stem cell transplant for relapsed non-Hodgkin lymphoma. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080701 |
| The naturally occurring flavolignan, deoxypodophyllotoxin, inhibits lipopolysaccharide-induced iNOS expression through the NF-kappaB activation in RAW264.7 macrophage cells. | Biological & pharmaceutical bulletin 20080701 |
| Modern management of external genital warts. | Journal of lower genital tract disease 20080701 |
| Metabolic stereoselectivity of cytochrome P450 3A4 towards deoxypodophyllotoxin: In silico predictions and experimental validation. | European journal of medicinal chemistry 20080601 |
| Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III. | Bioorganic & medicinal chemistry 20080601 |
| Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma. | Investigative ophthalmology & visual science 20080601 |
| Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor. | Investigative ophthalmology & visual science 20080601 |
| Design, synthesis and cytotoxicity of novel podophyllotoxin derivatives. | Chemical & pharmaceutical bulletin 20080601 |
| Podophyllotoxin directly binds a hinge domain in E2 of HPV and inhibits an E2/E7 interaction in vitro. | Bioorganic & medicinal chemistry 20080515 |
| Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes. | British journal of cancer 20080506 |
| Design and effective synthesis of the first 4-aza-2,3-didehydropodophyllotoxin rigid aminologue: a N-methyl-4-[(3,4,5-trimethoxyphenyl)amino)]-1,2-dihydroquinoline-lactone. | The Journal of organic chemistry 20080502 |
| Insulin growth factor signaling mediates neuron-like differentiation of adipose-tissue-derived stem cells. | Differentiation; research in biological diversity 20080501 |
| [Interest of lignans in prevention and treatment of cancers]. | Medecine sciences : M/S 20080501 |
| [Effects of podophyllotoxin solid lipid nanoparticles on proliferation and apoptosis of cervical carcinoma cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080501 |
| [Biotransformation of podophyllotoxin by cell suspension culture and root culture of Rheum palmatum]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501 |
| Structural simplification of bioactive natural products with multicomponent synthesis. 2. antiproliferative and antitubulin activities of pyrano[3,2-c]pyridones and pyrano[3,2-c]quinolones. | Journal of medicinal chemistry 20080424 |
| Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity. | Biochemistry 20080415 |
| Docetaxel-induced mitotic arrest in epithelium of gallbladder: a hitherto unreported occurrence. | International journal of surgical pathology 20080401 |
| Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum. | Journal of medicinal chemistry 20080313 |
| Synthesis of novel derivatives of bispodophyllotoxin as potential antineoplastic agents--part XVI. | Natural product research 20080310 |
| Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and beta-arrestin1. | Oncogene 20080306 |
| The construction and characterization of layered double hydroxides as delivery vehicles for podophyllotoxins. | Journal of materials science. Materials in medicine 20080301 |
| Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin. | Molecular pharmacology 20080301 |
| Dose-escalated CHOP and tailored intensification with IFE according to early response and followed by BEAM/autologous stem-cell transplantation in poor-risk aggressive B-cell lymphoma: a prospective study from the GEL-TAMO Study Group. | European journal of haematology 20080301 |
| Be wary, this is not a case of vulval warts! | International journal of STD & AIDS 20080301 |
| Novel three-component synthesis and antiproliferative properties of diversely functionalized pyrrolines. | Bioorganic & medicinal chemistry letters 20080215 |
| Seleno-podophyllotoxin derivatives induce hepatoma SMMC-7721 cell apoptosis through Bax pathway. | Cell biology international 20080201 |
| Design, synthesis, and biological testing of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin analogues as antitumor agents. | Archiv der Pharmazie 20080201 |
| Anti-osteosarcoma effects and mechanisms of 4-O-amino-phenol-4'-demethylepipodophyllotoxin ether. | The Journal of pharmacy and pharmacology 20080201 |
| Metabolic profiling of lignan variability in Linum species of section Syllinum native to Bulgaria. | Planta medica 20080201 |
| Exogenous hormones affecting morphology and biosynthetic potential of hairy root line (LYR2i) of Linum album. | Journal of bioscience and bioengineering 20080201 |
| Advances in the use of topical imiquimod to treat dermatologic disorders. | Therapeutics and clinical risk management 20080201 |
| Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids. | European journal of medicinal chemistry 20080101 |
| BEAC or BEAM high-dose chemotherapy followed by autologous stem cell transplantation in non-Hodgkin's lymphoma patients: comparative analysis of efficacy and toxicity. | Annals of hematology 20080101 |
| UDP-glucose:(6-methoxy)podophyllotoxin 7-O-glucosyltransferase from suspension cultures of Linum nodiflorum. | Phytochemistry 20080101 |
| Phase II trial of a transplantation regimen of yttrium-90 ibritumomab tiuxetan and high-dose chemotherapy in patients with non-Hodgkin's lymphoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080101 |
| Characterization of in vitro metabolites of deoxypodophyllotoxin in human and rat liver microsomes using liquid chromatography/tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20080101 |
| A fragmentation study of two compounds related to 4'-demethylepipodophyllotoxin in negative ion electrospray ionization by MSn ion-trap time-of-flight mass spectrometry. | Rapid communications in mass spectrometry : RCM 20080101 |
| Adding a quadrivalent human papillomavirus vaccine to the UK cervical cancer screening programme: A cost-effectiveness analysis. | Cost effectiveness and resource allocation : C/E 20080101 |
| Thiols oxidation and covalent binding of BSA by cyclolignanic quinones are enhanced by the magnesium cation. | Free radical research 20080101 |
| Bag culture: a method for root-root co-culture. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101 |
| Estimation of the incidence of genital warts and the cost of illness in Germany: a cross-sectional study. | BMC infectious diseases 20080101 |
| Podophyllotoxin from suspension culture of Linum album. | Natural product research 20080101 |
| Concise stereoselective synthesis of (-)-podophyllotoxin by an intermolecular iron(III)-catalyzed Friedel-Crafts alkylation. | Angewandte Chemie (International ed. in English) 20080101 |
| Application of cantharidin and podophyllotoxin for the treatment of plantar warts. | Journal of the American Podiatric Medical Association 20080101 |
| An experimental and computational study of effects of microtubule stabilization on T-cell polarity. | PloS one 20080101 |
| Total excision and V-Y plasty technique in the anal area condyloma acuminatum. | Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India 20080101 |
| A review on plant-derived natural products and their analogs with anti-tumor activity. | Indian journal of pharmacology 20080101 |
| 3-(2'-Bromopropionylamino)-benzamides as novel S-phase arrest agents. | Bioorganic & medicinal chemistry letters 20071215 |
| Pattern analysis of microtubule-polymerizing and -depolymerizing agent combinations as cancer chemotherapies. | International journal of oncology 20071201 |
| Reversal of P-glycoprotein-mediated drug efflux by eudesmin from Haplophyllum perforatum and cytotoxicity pattern versus diphyllin, podophyllotoxin and etoposide. | Planta medica 20071201 |
| Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20071129 |
| Synthesis and pharmacological evaluation of fluorescent and photoactivatable analogues of antiplasmodial naphthylisoquinolines. | Journal of medicinal chemistry 20071129 |
| Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations. | Journal of medicinal chemistry 20071115 |
| Synthesis and evaluation of antiparasitic activities of new 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine derivatives. | Journal of medicinal chemistry 20071115 |
| Quinuclidine derivatives as potential antiparasitics. | Antimicrobial agents and chemotherapy 20071101 |
| Marine natural products from the Turkish sponge Agelas oroides that inhibit the enoyl reductases from Plasmodium falciparum, Mycobacterium tuberculosis and Escherichia coli. | Bioorganic & medicinal chemistry 20071101 |
| Replacement of the lactone moiety on podophyllotoxin and steganacin analogues with a 1,5-disubstituted 1,2,3-triazole via ruthenium-catalyzed click chemistry. | Bioorganic & medicinal chemistry 20071101 |
| Frequency, severity and risk factors for oral mucositis after BEAM conditioning and autologous peripheral blood stem cell transplantation: a single center analysis and review of the literature. | Leukemia & lymphoma 20071101 |
| Discovery and investigation of antiproliferative and apoptosis-inducing properties of new heterocyclic podophyllotoxin analogues accessible by a one-step multicomponent synthesis. | Journal of medicinal chemistry 20071018 |
| Targeting the IGF-1R using picropodophyllin in the therapeutical 5T2MM mouse model of multiple myeloma: beneficial effects on tumor growth, angiogenesis, bone disease and survival. | International journal of cancer 20071015 |
| Silenes in organic synthesis: a concise synthesis of (+/-) -epi-picropodophyllin. | Organic & biomolecular chemistry 20071007 |
| Rho guanosine 5'-triphosphatases differentially regulate insulin-like growth factor I (IGF-I) receptor-dependent and -independent actions of IGF-II on human trophoblast migration. | Endocrinology 20071001 |
| Creatine enhances differentiation of myogenic C2C12 cells by activating both p38 and Akt/PKB pathways. | American journal of physiology. Cell physiology 20071001 |
| Primary refractory Hodgkin's lymphoma: outcome after high-dose chemotherapy and autologous SCT and impact of various prognostic factors on overall and event-free survival. A single institution result of 66 patients. | Bone marrow transplantation 20071001 |
| Insight into the GTPase activity of tubulin from complexes with stathmin-like domains. | Biochemistry 20070918 |
| Synthesis, biological evaluation, and molecular modeling of 3,5-substituted-N1-phenyl-N4,N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents. | Bioorganic & medicinal chemistry 20070915 |
| Synthesis and insecticidal activities of novel derivatives of podophyllotoxin. | Natural product research 20070901 |
| Design, synthesis, and biological evaluation of novel spin-labeled derivatives of podophyllotoxin as potential antineoplastic agents. Part XII. | Natural product research 20070901 |
| Anti-malarial activity of N6-modified purine analogues. | Bioorganic & medicinal chemistry 20070815 |
| Sesquiterpenoids and cytotoxic lignans from the bark of Libocedrus chevalieri. | Journal of natural products 20070801 |
| Treatment of ano-genital warts: the effect of an educational event on practitioner choice. | International journal of STD & AIDS 20070801 |
| Treatment of molluscum contagiosum: a brief review and discussion of a case successfully treated with adapelene. | Dermatology online journal 20070713 |
| Novel potent antimitotic heterocyclic ketones: synthesis, antiproliferative activity, and structure-activity relationships. | Bioorganic & medicinal chemistry letters 20070701 |
| GP7 induces internucleosomal DNA fragmentation independent of caspase activation and DNA fragmentation factor in NB4 cells. | Oncology reports 20070701 |
| The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling. | Journal of vascular surgery 20070701 |
| Secondary acute myelogenous leukemia in patients with retinoblastoma: is chemotherapy a factor? | Ophthalmology 20070701 |
| Antioxidative and antitumor activity of derivatives of 4-beta-amino-4'-demethylepipodophyllotoxin and their structure-activity relationship. | Die Pharmazie 20070601 |
| Protective efficacy of semi purified fraction of high altitude podophyllum hexandrum rhizomes in lethally irradiated Swiss albino mice. | Cellular and molecular biology (Noisy-le-Grand, France) 20070530 |
| Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles. | Journal of medicinal chemistry 20070517 |
| Aryltetralin-lignan formation in two different cell suspension cultures of Linum album: deoxypodophyllotoxin 6-hydroxylase, a key enzyme for the formation of 6-methoxypodophyllotoxin. | Phytochemistry 20070501 |
| A second autologous transplant may be efficacious in selected patients with Hodgkin's lymphoma relapsing after a previous autograft. | Leukemia & lymphoma 20070501 |
| [Treatment of recurrent condyloma acuminatum with solid lipid nanoparticle gel containing podophyllotoxin: a randomized double-blinded, controlled clinical trial]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070501 |
| Synthesis and anti-HIV-1 activities of novel podophyllotoxin derivatives. | Bioorganic & medicinal chemistry letters 20070401 |
| Yttrium-90-ibritumomab tiuxetan (Zevalin) combined with high-dose BEAM chemotherapy and autologous stem cell transplantation for chemo-refractory aggressive non-Hodgkin's lymphoma. | Experimental hematology 20070401 |
| Podophyllotoxin content, above- and belowground biomass in relation to altitude in Podophyllum hexandrum populations from Kumaun region of the Indian Central Himalaya. | Planta medica 20070401 |
| The contribution of oxazolidinone frame to the biological activity of pharmaceutical drugs and natural products. | Mini reviews in medicinal chemistry 20070401 |
| [Transdermal fentanyl in treating severe painful mucositis caused by autologous hematopoietic stem cell transplantation]. | Ai zheng = Aizheng = Chinese journal of cancer 20070401 |
| The diagnosis and treatment of human papillomavirus-mediated genital lesions. | Cutis 20070401 |
| A new and efficient strategy for the synthesis of podophyllotoxin and its analogues. | Organic letters 20070329 |
| In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth. | Blood 20070315 |
| Picropodophyllotoxin or podophyllotoxin does not induce cell death via insulin-like growth factor-I receptor. | Cancer research 20070315 |
| Structural simplification of bioactive natural products with multicomponent synthesis: dihydropyridopyrazole analogues of podophyllotoxin. | Bioorganic & medicinal chemistry letters 20070301 |
| Novel pyridinyl and pyrimidinylcarbazole sulfonamides as antiproliferative agents. | Bioorganic & medicinal chemistry letters 20070301 |
| Long-term follow-up of endoscopic therapy of anal canal condylomata acuminata with podophyllotoxin. | Journal of the European Academy of Dermatology and Venereology : JEADV 20070301 |
| Targeted therapies in adult soft tissue sarcomas. | Journal of surgical oncology 20070301 |
| Palifermin and palmar-plantar erythrodysesthesia. | British journal of haematology 20070301 |
| Synthesis and cytotoxic evaluation of C-9 oxidized podophyllotoxin derivatives. | Bioorganic & medicinal chemistry 20070215 |
| Tandem high-dose chemotherapy and autologous stem cell transplantation in refractory/relapsed Hodgkin's lymphoma: a monocenter prospective study. | American journal of hematology 20070201 |
| Lignans from Dysosma versipellis with inhibitory effects on prostate cancer cell lines. | Journal of natural products 20070201 |
| Factors influencing engraftment in autologous peripheral hematopoetic stem cell transplantation (PBSCT). | Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20070201 |
| [What is your diagnosis? Neutropenic colitis (neutropenic typhlitis)]. | Praxis 20070124 |
| Insulin-like growth factor-I is an important antiapoptotic factor for rat leydig cells during postnatal development. | Endocrinology 20070101 |
| Promotion of tubulin assembly by poorly soluble taxol analogs. | Analytical biochemistry 20070101 |
| Combination chemotherapy followed by autologous stem cell transplant for enteropathy-associated T cell lymphoma. | British journal of haematology 20070101 |
| Two cases of secondary acute myeloid leukemia accompanying adult T-cell leukemia/lymphoma. | International journal of hematology 20070101 |
| Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I). | Advances in cancer research 20070101 |
| Root cultures of linum species section Syllinum as rich sources of 6-methoxypodophyllotoxin. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101 |
| A fragmentation study of podophyllotoxin and its 4'-demethyl-4beta-substituted derivatives by electrospray ionization ion-trap time-of-flight tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20070101 |
| Induction of apoptosis by alkaloids, non-protein amino acids, and cardiac glycosides in human promyelotic HL-60 cells. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101 |
| Genital warts treated by photodynamic therapy. | Skinmed 20070101 |
| Treatment outcome and cost-effectiveness analysis of two chemotherapeutic regimens (BEP vs. VIP) for poor-prognosis metastatic germ cell tumors. | Journal of cancer research and therapeutics 20070101 |
| Warts (genital). | BMJ clinical evidence 20070101 |
| The roles of beta-tubulin mutations and isotype expression in acquired drug resistance. | Cancer informatics 20070101 |
| 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20061228 |
| Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding. | The FEBS journal 20061201 |
| Podophyllum hexandrum Offers Radioprotection by Modulating Free Radical Flux: Role of Aryl-Tetralin Lignans. | Evidence-based complementary and alternative medicine : eCAM 20061201 |
| Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4. | Journal of biotechnology 20061110 |
| Synthesis and biological evaluation of new 4beta-5-Fu-substituted 4'-demethylepipodophyllotoxin derivatives. | Molecules (Basel, Switzerland) 20061102 |
| In vitro antiprotozoal activity of the lipophilic extracts of different parts of Turkish Pistacia vera L. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20061101 |
| Synthesis and structure-activity relationships of carbazole sulfonamides as a novel class of antimitotic agents against solid tumors. | Journal of medicinal chemistry 20061019 |
| Outpatient autologous hematopoietic stem cell transplantation for patients with relapsed follicular lymphoma. | Annals of hematology 20061001 |
| Structure-activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416. | Bioorganic & medicinal chemistry 20061001 |
| Autologous peripheral blood stem cell transplantation for severe multiple sclerosis. | International journal of hematology 20061001 |
| Nursing care and treatment of the patient with human papillomavirus. | British journal of nursing (Mark Allen Publishing) 20061001 |
| Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin. | Journal of medicinal chemistry 20060921 |
| [4-(imidazol-1-yl)thiazol-2-yl]phenylamines. A novel class of highly potent colchicine site binding tubulin inhibitors: synthesis and cytotoxic activity on selected human cancer cell lines. | Journal of medicinal chemistry 20060921 |
| IGF-1R tyrosine kinase expression and dependency in clones of IGF-1R knockout cells (R-). | Biochemical and biophysical research communications 20060908 |
| Prolonged remission in a case of Richter's transformation of B-cell chronic lymphocytic leukaemia following adoptive immunotherapy. | Bone marrow transplantation 20060901 |
| Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060801 |
| Endophyte fungal isolates from Podophyllum peltatum produce podophyllotoxin. | Journal of natural products 20060801 |
| Synthesis and cytotoxicity of racemic isodeoxypodophyllotoxin analogues with isoprene-derived side chains. | Journal of natural products 20060801 |
| Morbidity and transplant-related mortality of CBV and BEAM preparative regimens for patients with lymphoid malignancies undergoing autologous stem-cell transplantation. | Leukemia & lymphoma 20060801 |
| Design, synthesis and evaluation of novel uracil amino acid conjugates for the inhibition of Trypanosoma cruzi dUTPase. | Bioorganic & medicinal chemistry letters 20060715 |
| Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. | Journal of medicinal chemistry 20060713 |
| Deoxypodophyllotoxin (DPT) inhibits eosinophil recruitment into the airway and Th2 cytokine expression in an OVA-induced lung inflammation. | Planta medica 20060701 |
| Frequency and timing of leaf removal affect growth and podophyllotoxin content of Podophyllum peltatum in full sun. | Planta medica 20060701 |
| Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents. | Journal of medicinal chemistry 20060629 |
| Upfront double high-dose chemotherapy with DICEP followed by BEAM and autologous stem cell transplantation for poor-prognosis aggressive non-Hodgkin lymphoma. | Blood 20060615 |
| Molecular identification of Sinopodophyllum hexandrum and Dysosma species using cpDNA sequences and PCR-RFLP markers. | Planta medica 20060601 |
| Medicinal chemistry approaches to target the kinase activity of IGF-1R. | IDrugs : the investigational drugs journal 20060601 |
| Palifermin for oral mucositis in the high-dose chemotherapy and stem cell transplant setting: the Royal Adelaide Hospital Cancer Centre experience. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20060601 |
| Genital warts. | Clinical evidence 20060601 |
| Recent patents therapeutic agents for cancer. | Recent patents on anti-cancer drug discovery 20060601 |
| The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection. | Oncogene 20060525 |
| Oxalone and lactone moieties of podophyllotoxin exhibit properties of both the B and C rings of colchicine in its binding with tubulin. | Biochemistry 20060523 |
| Synthesis and biological evaluation of new spin-labeled derivatives of podophyllotoxin. | Bioorganic & medicinal chemistry 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Randomised phase III study of R-ICE versus R-DHAP in relapsed patients with CD20 diffuse large B-cell lymphoma (DLBCL) followed by high-dose therapy and a second randomisation to maintenance treatment with rituximab or not: an update of the CORAL study. | Annals of oncology : official journal of the European Society for Medical Oncology 20060501 |
| Successful autologous hematopoietic stem cell transplantations for severe multiple sclerosis with fludarabine and cyclophosphamide conditioning. | International journal of hematology 20060501 |
| [Studies on the interaction of the metal complex of hydrazide of podophyllic acid with DNA]. | Guang pu xue yu guang pu fen xi = Guang pu 20060501 |
| [Study on extraction methods of activity components from Podophyllum emodi wall]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060501 |
| The endophytic fungus Trametes hirsuta as a novel alternative source of podophyllotoxin and related aryl tetralin lignans. | Journal of biotechnology 20060420 |
| Benzoylphenylurea sulfur analogues with potent antitumor activity. | Journal of medicinal chemistry 20060406 |
| Incidence and clinical relevance of abnormal complete blood counts in long-term survivors of childhood cancer. | Cancer 20060401 |
| Evaluation of cytotoxic potential of latex of Calotropis procera and podophyllotoxin in Allium cepa root model. | Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al 20060401 |
| Thiocolchicine-podophyllotoxin conjugates: dynamic libraries based on disulfide exchange reaction. | The Journal of organic chemistry 20060331 |
| An evidence-based review of medical and surgical treatments of genital warts. | Dermatology online journal 20060330 |
| Secoisolariciresinol dehydrogenase: mode of catalysis and stereospecificity of hydride transfer in Podophyllum peltatum. | Organic & biomolecular chemistry 20060307 |
| Alkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents. | Bioorganic & medicinal chemistry letters 20060301 |
| Efficacy of diverse high-dose regimens followed by autologous peripheral blood stem cell transplantation in consecutive multiple myeloma patients: a single-centre analysis over a 12-year period. | Annals of hematology 20060301 |
| Immunology and homeopathy. 2. Cells of the immune system and inflammation. | Evidence-based complementary and alternative medicine : eCAM 20060301 |
| The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060215 |
| Successful autologous peripheral blood stem cell harvest and transplant in a patient with cold agglutinins. | Bone marrow transplantation 20060201 |
| Protection of the hemopoietic system by Podophyllum hexandrum against gamma radiation-induced damage. | Planta medica 20060201 |
| Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model. | Blood 20060115 |
| IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells. | Blood 20060115 |
| Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting. | Journal of controlled release : official journal of the Controlled Release Society 20060110 |
| Trial of amifostine in autologous stem cell transplant. | Bone marrow transplantation 20060101 |
| Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data. | Anti-cancer drugs 20060101 |
| L-carnitine inhibits apoptotic DNA fragmentation induced by a new spin-labeled derivative of podophyllotoxin via caspase-3 in Raji cells. | Oncology reports 20060101 |
| Prophylaxis of central venous catheter-related thrombosis with minidose warfarin in patients treated with high-dose chemotherapy and peripheral-blood stem-cell transplantation: retrospective analysis of 228 cancer patients. | American journal of hematology 20060101 |
| Isoflavonoids and other compounds from Psorothamnus arborescens with antiprotozoal activities. | Journal of natural products 20060101 |
| Camptothecin and podophyllotoxin derivatives: inhibitors of topoisomerase I and II - mechanisms of action, pharmacokinetics and toxicity profile. | Drug safety 20060101 |
| [Studies on antitumor effects of podophyllotoxin nanoliposome]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060101 |
| Aspects of early arthritis. Traditional DMARD therapy: is it sufficient? | Arthritis research & therapy 20060101 |
| Characterization of two epimers, 4alpha and 4beta, of a novel podophyllotoxin-4-O-(D)-6-acetylglucopyranoside from Podophyllum hexandrum by LC-ESI-MS-MS. | Journal of chromatographic science 20060101 |
| Colchitaxel, a coupled compound made from microtubule inhibitors colchicine and paclitaxel. | Beilstein journal of organic chemistry 20060101 |
| Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma. | World journal of surgical oncology 20060101 |
| Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression. | Molecular neurodegeneration 20060101 |
| Meta-analysis of 5% imiquimod and 0.5% podophyllotoxin in the treatment of condylomata acuminata. | Dermatology (Basel, Switzerland) 20060101 |
| Taxane-resistant lymphoepithelial-like carcinoma: excellent response to VIP chemotherapy. | Irish journal of medical science 20060101 |
| Deoxypodophyllotoxin content and antioxidant activity of aerial parts of Anthriscus sylvestris Hoffm. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101 |
| Conformationally restricted analogs of Combretastatin A-4 derived from SU5416. | Bioorganic & medicinal chemistry letters 20051215 |
| Randomized controlled trial of an adjuvanted human papillomavirus (HPV) type 6 L2E7 vaccine: infection of external anogenital warts with multiple HPV types and failure of therapeutic vaccination. | The Journal of infectious diseases 20051215 |
| Bioactive constituents from roots of Bursera tonkinensis. | Phytochemistry 20051201 |
| Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate. | Journal of medicinal chemistry 20051117 |
| Synthesis and biological evaluation of new 4beta-anilino- and 4beta-imido-substituted podophyllotoxin congeners. | Bioorganic & medicinal chemistry 20051115 |
| Discovery of novel immunostimulants by dendritic-cell-based functional screening. | Blood 20051101 |
| Methyltrioxorhenium catalysed synthesis of highly oxidised aryltetralin lignans with anti-topoisomerase II and apoptogenic activities. | Bioorganic & medicinal chemistry 20051101 |
| Plant-based anticancer molecules: a chemical and biological profile of some important leads. | Bioorganic & medicinal chemistry 20051101 |
| Enhancement of lignan biosynthesis in suspension cultures of Linum nodiflorum by coronalon, indanoyl-isoleucine and methyl jasmonate. | Planta 20051101 |
| Development of an enzyme-linked immunosorbent assay for podophyllotoxin. | International immunopharmacology 20051001 |
| Ifosfamide, epirubicin, etoposide (IEV) and autologous peripheral blood progenitor cell transplant: a feasible and effective salvage treatment for lymphoid malignancies. | Oncology reports 20051001 |
| A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. | Journal of medicinal chemistry 20050922 |
| Florid cutaneous papillomatosis leading to social exclusion. | The British journal of dermatology 20050901 |
| Chemotherapy-induced hypersensitivity reactions. | Oncology nursing forum 20050901 |
| Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles. | British journal of cancer 20050822 |
| Apoptosis induced by one new podophyllotoxin glucoside in human carcinoma cells. | Toxicology 20050815 |
| Cytotoxicity, apoptosis induction, and mitotic arrest by a novel podophyllotoxin glucoside, 4DPG, in tumor cells. | Acta pharmacologica Sinica 20050801 |
| Influence of methyl jasmonate on podophyllotoxin and 6-methoxypodophyllotoxin accumulation in Linum album cell suspension cultures. | Plant cell reports 20050701 |
| A phase Ib clinical trial of PV701, a milk-derived protein extract, for the prevention and treatment of oral mucositis in patients undergoing high-dose BEAM chemotherapy. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050701 |
| Expression and growth dependency of the insulin-like growth factor I receptor in craniopharyngioma cells: a novel therapeutic approach. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050701 |
| Pinoresinol-lariciresinol reductases with different stereospecificity from Linum album and Linum usitatissimum. | Phytochemistry 20050601 |
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
| Genital warts. | Clinical evidence 20050601 |
| Synthesis and identification of antigenic conjugates of podophyllotoxin. | Yao xue xue bao = Acta pharmaceutica Sinica 20050601 |
| Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound. | Journal of natural products 20050501 |
| Synthesis and biological activity of new class of dioxygenated anticancer agents. | Current medicinal chemistry. Anti-cancer agents 20050501 |
| Insulin-like growth factor-I receptor activity is essential for Kaposi's sarcoma growth and survival. | British journal of cancer 20050425 |
| Crystal structures of apo-form and binary/ternary complexes of Podophyllum secoisolariciresinol dehydrogenase, an enzyme involved in formation of health-protecting and plant defense lignans. | The Journal of biological chemistry 20050401 |
| Synthesis and in vitro cytotoxic activity of N-, F-, and S-ether derivatives of podophyllotoxin fatty acid adducts. | Lipids 20050401 |
| Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation. | Organic & biomolecular chemistry 20050321 |
| Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life. | Blood 20050315 |
| Toxicity of the topoisomerase II inhibitors. | Expert opinion on drug safety 20050301 |
| A cross-sectional survey of treatment choices for anogenital warts. | International journal of STD & AIDS 20050301 |
| Anticancer activity and possible mode of action of 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate. | Lipids 20050301 |
| [An experimental study on proliferative effects and apoptotic effects of podophyllic acid in K562 cells]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050201 |
| Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives. | Journal of medicinal chemistry 20050127 |
| [Preparation of stearic acid solid lipid nanoparticles containing podophyllotoxin]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050101 |
| [4-Aza-2,3-didehydropodophyllotoxins: new lignan with antitumor activity obtained from one-step synthesis]. | Annales pharmaceutiques francaises 20050101 |
| Condyloma with lichen nitidus. | Skinmed 20050101 |
| Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. | Current pharmaceutical design 20050101 |
| Linum mucronatum: organ to organ lignan variations. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101 |
| Genital warts: current and future management options. | American journal of clinical dermatology 20050101 |
| Grade 3 vulvar and anal intraepithelial neoplasia in a HIV seropositive child--therapeutic result: case report. | Clinical and experimental obstetrics & gynecology 20050101 |
| Cytotoxic activity of a podophyllotoxin-like lignan from Linum tauricum Willd. | Neoplasma 20050101 |
| ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal. | Cancer cell international 20050101 |
| Genital infection with human papillomavirus in adolescents. | Advances in therapy 20050101 |
| Human papillomavirus: burden of illness and treatment cost considerations. | American journal of clinical dermatology 20050101 |
| Radioprotective and antioxidant properties of low-altitude Podophyllum hexandrum (LAPH). | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20050101 |
| Management of genital warts. | American family physician 20041215 |
| Microtubulin binding sites as target for developing anticancer agents. | Mini reviews in medicinal chemistry 20041201 |
| Lignan accumulation in cell cultures of Linum strictum ssp. strictum L. | Acta pharmaceutica (Zagreb, Croatia) 20041201 |
| Pearly penile lesions. | The Journal of family practice 20041101 |
| Insecticidal activity of deoxypodophyllotoxin, isolated from Juniperus sabina L, and related lignans against larvae of Pieris rapae L. | Pest management science 20041101 |
| Synthesis and cytotoxic activity of novel derivatives of 4'-demethylepipodophyllotoxin. | Bioorganic & medicinal chemistry letters 20041018 |
| The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway. | Oncogene 20041014 |
| Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4beta-[(4' '-benzamido)-amino]-4'-o-demethyl-epipodophyllotoxin derivatives. | Journal of medicinal chemistry 20041007 |
| High-dose CEB vs BEAM with autologous stem cell transplant in lymphoma. | Bone marrow transplantation 20041001 |
| Low-dose oral etoposide-based induction regimen for children with acute lymphoblastic leukemia in first bone marrow relapse. | Leukemia 20041001 |
| Biotechnological aspects of the production of the anticancer drug podophyllotoxin. | Applied microbiology and biotechnology 20041001 |
| Lignoids in insects: chemical probes for the study of ecdysis, excretion and Trypanosoma cruzi-triatomine interactions. | Toxicon : official journal of the International Society on Toxinology 20040915 |
| Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives. | Toxicon : official journal of the International Society on Toxinology 20040915 |
| Mass spectrometric measurement of differential reactivity of cysteine to localize protein-ligand binding sites. Application to tubulin-binding drugs. | Analytical biochemistry 20040915 |
| Design, synthesis, biological evaluation and QSAR studies of novel bisepipodophyllotoxins as cytotoxic agents. | Bioorganic & medicinal chemistry 20040801 |
| Anti-AIDS agents. Part 61: Anti-HIV activity of new podophyllotoxin derivatives. | Bioorganic & medicinal chemistry 20040801 |
| Remission of acute monocytic leukemia, secondary to treatment with epipodophyllotoxins, in a patient with t(8;16)(p11;p13) and MYST3-CREBBP fusion. | Cancer genetics and cytogenetics 20040715 |
| Roles of NF-kappaB and SP-1 in oxidative stress-mediated induction of platelet-derived growth factor-B by TNFalpha in human endothelial cells. | Journal of cardiovascular pharmacology 20040701 |
| [Preparation and characterization of podophyllotoxin-dipalmitoylphosphatidylcholine proliposome]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20040701 |
| Synthesis, spectroscopic, and biological studies of novel estolides derived from anticancer active 4-O-podophyllotoxinyl 12-hydroxyl-octadec-Z-9-enoate. | Lipids 20040701 |
| Antitumor agents. Part 227: Studies on novel 4'-O-demethyl-epipodophyllotoxins as antitumor agents targeting topoisomerase II. | Bioorganic & medicinal chemistry 20040615 |
| Critical appraisal of commonly used treatment for genital warts. | International journal of STD & AIDS 20040601 |
| Dual inhibition of cyclooxygenases-2 and 5-lipoxygenase by deoxypodophyllotoxin in mouse bone marrow-derived mast cells. | Biological & pharmaceutical bulletin 20040601 |
| Comparison of different extraction methods for the determination of podophyllotoxin and 6-methoxypodophyllotoxin in Linum species. | Journal of pharmaceutical and biomedical analysis 20040528 |
| A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel. | Cancer chemotherapy and pharmacology 20040501 |
| Patient assessment of anogenital warts and the success of treatment with home applied therapy. | International journal of STD & AIDS 20040501 |
| Effects of microtubule-depolymerizing agents on the transfection of cultured vascular smooth muscle cells: enhanced expression with free drug and especially with drug-gene lipoplexes. | Molecular therapy : the journal of the American Society of Gene Therapy 20040501 |
| Deoxypodophyllotoxin, a naturally occurring lignan, inhibits the passive cutaneous anaphylaxis reaction. | Planta medica 20040501 |
| A novel podophyllotoxin lignan from Justicia heterocarpa. | Chemical & pharmaceutical bulletin 20040501 |
| Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin. | Journal of medicinal chemistry 20040422 |
| alphaB-Crystallin-coated MAP microtubule resists nocodazole and calcium-induced disassembly. | Journal of cell science 20040401 |
| [Preparation of liposome podophyllotoxin chitosan film and determination the podophyllotoxin content in the film by ultraviolet spectrophotometry]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20040401 |
| Deoxypodophyllotoxin reduces skin pigmentation of brown Guinea pigs. | Planta medica 20040401 |
| New chromanone acids with antibacterial activity from Calophyllum brasiliense. | Journal of natural products 20040401 |
| Alpha-conidendrin as a source for preparation of sikkimotoxin derivatives. | Journal of natural products 20040401 |
| Antitumor agents. Part 232: Synthesis of cyclosulfite podophyllotoxin analogues as novel prototype antitumor agents. | Bioorganic & medicinal chemistry letters 20040322 |
| Synthesis and cytotoxicity of hydrophobic esters of podophyllotoxins. | Bioorganic & medicinal chemistry letters 20040308 |
| Synthesis and biological evaluation of new selective cytotoxic cyclolignans derived from podophyllotoxin. | Journal of medicinal chemistry 20040226 |
| Sexually transmissible infections other than HIV. | Lancet (London, England) 20040214 |
| Cytotoxicity of in vitro produced podophyllotoxin from Podophyllum hexandrum on human cancer cell line. | Natural product research 20040201 |
| Antineoplastic agents. 522. Hernandia peltata (Malaysia) and Hernandia nymphaeifolia (Republic of Maldives). | Journal of natural products 20040201 |
| Alkyl and carboxylalkyl esters of 4'-demethyl-4-deoxypodophyllotoxin: synthesis, cytotoxic, and antitumor activity. | European journal of medicinal chemistry 20040201 |
| Synthesis and anticancer activities of fatty acid analogs of podophyllotoxin. | Lipids 20040201 |
| A concise stereocontrolled formal total synthesis of (+/-)-podophyllotoxin using sulfoxide chemistry. | Chemical communications (Cambridge, England) 20040121 |
| GP7 can induce apoptotic DNA fragmentation of human leukemia cells through caspase-3-dependent and -independent pathways. | International journal of molecular medicine 20040101 |
| Pharmacokinetic optimisation of treatment with oral etoposide. | Clinical pharmacokinetics 20040101 |
| Radioprotective effect of podophyllotoxin in Saccharomyces cerevisiae. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101 |
| Analysis of neutral drugs in human plasma by fluoride attachment in liquid chromatography/negative ion electrospray tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20040101 |
| Therapy of cutaneous human Papillomavirus infections. | Dermatologic therapy 20040101 |
| [The multidrug tumor cell resistance phenotype caused by the impaired cell death program]. | Vestnik Rossiiskoi akademii meditsinskikh nauk 20040101 |
| [Autologous stem-cell transplantations in children with non-Hodgkin lymphomas]. | Przeglad lekarski 20040101 |
| Human papillomavirus infections: diagnosis, treatment, and hope for a vaccine. | Obstetrics and gynecology clinics of North America 20031201 |
| Synthesis of 4beta-amido and 4beta-sulphonamido analogues of podophyllotoxin as potential antitumour agents. | Bioorganic & medicinal chemistry 20031117 |
| LAV694, a new antiproliferative agent showing improved skin tolerability vs. clinical standards for the treatment of actinic keratosis. | Biochemical pharmacology 20031115 |
| Extensive condyloma acuminata treated with imiquimod 5% cream: a case report. | Clinical and experimental dermatology 20031101 |
| The intramolecular carboxyarylation approach to podophyllotoxin. | Journal of the American Chemical Society 20031008 |
| Synthesis, cytotoxicity and antiviral activity of podophyllotoxin analogues modified in the E-ring. | European journal of medicinal chemistry 20031001 |
| [Human papillomaviruses]. | Therapeutische Umschau. Revue therapeutique 20031001 |
| Beta-peltatin 6-O-methyltransferase from suspension cultures of Linum nodiflorum. | Phytochemistry 20030901 |
| Enhancement of radiation-induced apoptosis by Podophyllum hexandrum. | The Journal of pharmacy and pharmacology 20030901 |
| Antitumor activity of unsaturated fatty acid esters of 4'-demethyldeoxypodophyllotoxin. | Bioorganic & medicinal chemistry letters 20030818 |
| A mathematical model for reconstitution of granulopoiesis after high dose chemotherapy with autologous stem cell transplantation. | Journal of mathematical biology 20030801 |
| Randomised controlled trial and economic evaluation of podophyllotoxin solution, podophyllotoxin cream, and podophyllin in the treatment of genital warts. | Sexually transmitted infections 20030801 |
| A phytochemical study of lignans in whole plants and cell suspension cultures of Anthriscus sylvestris. | Planta medica 20030801 |
| The bioconversion process of deoxypodophyllotoxin with Linum flavum cell cultures. | Planta medica 20030801 |
| The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter. | The Journal of biological chemistry 20030718 |
| Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20030717 |
| In vitro cytotoxicity of aplidin and crossresistance with other cytotoxic drugs in childhood leukemic and normal bone marrow and blood samples: a rational basis for clinical development. | Leukemia 20030701 |
| Biotransformation of a dibenzylbutanolide to podophyllotoxin analogues by shoot cultures of Haplophyllum patavinum. | Chemical & pharmaceutical bulletin 20030701 |
| BEAC or BEAM for high-dose therapy in patients with non-Hodgkin's lymphoma? A single centre analysis on toxicity and efficacy. | Leukemia & lymphoma 20030701 |
| Efficient enantioselective total synthesis of (-)-epipodophyllotoxin. | Angewandte Chemie (International ed. in English) 20030606 |
| Cytotoxic and cytostatic activity of erlangerins from Commiphora erlangeriana. | Toxicon : official journal of the International Society on Toxinology 20030501 |
| A hybrid form of myeloid/NK-cell acute leukemia and myeloid/NK-cell precursor acute leukemia. | Human pathology 20030501 |
| Variation of podophyllotoxin in leaves of Eastern Red Cedar (Juniperus virginiana). | Planta medica 20030501 |
| Bioactivity of secoiridoid glycosides from Centaurium erythraea. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20030501 |
| [Therapy-related acute leukaemia and myelodysplastic syndrome]. | Anales de medicina interna (Madrid, Spain : 1984) 20030501 |
| Synthesis, anticancer activity, and inhibition of tubulin polymerization by conformationally restricted analogues of lavendustin A. | Journal of medicinal chemistry 20030424 |
| Transcription factor IID recruitment and Sp1 activation. Dual function of TAF1 in cyclin D1 transcription. | The Journal of biological chemistry 20030411 |
| The cost-effectiveness of patient-applied treatments for anogenital warts. | International journal of STD & AIDS 20030401 |
| Er:YAG laser followed by topical podophyllotoxin for hard-to-treat palmoplantar warts. | Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology 20030401 |
| Modes of methyleneoxy bridging and their effect on tetrahydronaphthalene lignan cytotoxicity. | Journal of medicinal chemistry 20030327 |
| Podophyllum peltatum possesses a beta-glucosidase with high substrate specificity for the aryltetralin lignan podophyllotoxin. | Biochimica et biophysica acta 20030321 |
| Dearomatizing cyclization of arylsulfonylalkoxymethyl lithiums: a route to the podophyllotoxin skeleton. | Organic letters 20030320 |
| [Bacteremia due to Capnocytophaga spp.: two cases]. | Enfermedades infecciosas y microbiologia clinica 20030301 |
| Preparation and comparative analysis of two podophyllotoxin liposomes. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030301 |
| Naphthalene analogues of lignans. | The Journal of organic chemistry 20030207 |
| Algicidal activity and gliding motility of Saprospira sp. SS98-5. | Canadian journal of microbiology 20030201 |
| Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma. | British journal of cancer 20030113 |
| High-dose therapy in diffuse large cell lymphoma: results and prognostic factors in 452 patients from the GEL-TAMO Spanish Cooperative Group. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
| Effect of major nutrients on podophyllotoxin production in Podophyllum hexandrum suspension cultures. | Applied microbiology and biotechnology 20030101 |
| Synthesis and cytotoxicity of podophyllotoxin analogues modified in the A ring. | European journal of medicinal chemistry 20030101 |
| Taxanes in the treatment of advanced (stage III and IV) non-small cell lung cancer (NSCLC): recent developments. | Cancer investigation 20030101 |
| Late effects of treatment for cancer during childhood and adolescence. | Current problems in cancer 20030101 |
| Enhanced production of podophyllotoxin by Podophyllum hexandrum using in situ cell retention bioreactor. | Biotechnology progress 20030101 |
| CPH 82. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20030101 |
| Production of podophyllotoxin using cross-species coculture of Linum flavum hairy roots and Podophyllum hexandrum cell suspensions. | Biotechnology progress 20030101 |
| [A model-based comparison of cost effectiveness of imiquimod versus podophyllotoxin for the treatment of external anogenital warts in France]. | Annales de dermatologie et de venereologie 20030101 |
| Pervilleine F, a new tropane alkaloid aromatic ester that reverses multidrug resistance. | Anticancer research 20030101 |
| An epiisopicropodophyllin aza analogue via palladium-catalyzed pseudo-domino cyclization. | The Journal of organic chemistry 20021227 |
| Chemoresistant or aggressive lymphoma predicts for a poor outcome following reduced-intensity allogeneic progenitor cell transplantation: an analysis from the Lymphoma Working Party of the European Group for Blood and Bone Marrow Transplantation. | Blood 20021215 |
| Prodrugs of 4'-demethyl-4-deoxypodophyllotoxin: synthesis and evaluation of the antitumor activity. | Bioorganic & medicinal chemistry letters 20021202 |
| Hemi-synthesis and biological activity of new analogues of podophyllotoxin. | Bioorganic & medicinal chemistry 20021101 |
| Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay. | Journal of natural products 20021101 |
| External genital warts: diagnosis, treatment, and prevention. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021015 |
| Meiotic telomere clustering is inhibited by colchicine but does not require cytoplasmic microtubules. | Journal of cell science 20021001 |
| Methamphetamine activates DNA binding of specific redox-responsive transcription factors in mouse brain. | Journal of neuroscience research 20021001 |
| Biosynthesis of podophyllotoxin in Linum album cell cultures. | Planta 20021001 |
| Experimental study of podophyllotoxin dipalmitoylphosphatidylcholine liposome for topical skin application. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021001 |
| Zinc enhances the expression of interleukin-2 and interleukin-2 receptors in HUT-78 cells by way of NF-kappaB activation. | The Journal of laboratory and clinical medicine 20021001 |
| Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. | Journal of natural products 20021001 |
| A multicomponent reaction for the one-pot synthesis of 4-aza-2,3-didehydropodophyllotoxin and derivatives. | Organic letters 20020919 |
| Cytogenetic analysis of giant oocytes and zygotes to assess their relevance for the development of digynic triploidy. | Human reproduction (Oxford, England) 20020901 |
| [Changes in serum concentration of podophyllotoxin after its topical application with liposome on rat skin]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020901 |
| Four lignans from Commiphora erlangeriana. | Journal of natural products 20020901 |
| Antioxidative activity of spin labeled derivatives of podophyllic acid hydrazide. | Acta pharmacologica Sinica 20020801 |
| Biological activity of 4-acetyltropolone, the minor component of Thujopsis dolabrata SIeb. et Zucc. hondai Mak. | Biological & pharmaceutical bulletin 20020801 |
| [Poisoning with a podophyllin-containing wart-treating tincture]. | Deutsche medizinische Wochenschrift (1946) 20020712 |
| Unusual implantation site of a port-a-cath system via the right femoral vein. | Journal of cancer research and clinical oncology 20020701 |
| Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: in vivo antimalarial activity and X-ray crystal structure of normelicopicine. | Journal of natural products 20020701 |
| A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents. | Biochemistry 20020625 |
| Microtubule damaging agents induce apoptosis in HL 60 cells and G2/M cell cycle arrest in HT 29 cells. | Toxicology 20020614 |
| Flow cytometric estimation on cytotoxic activity of leaf extracts from seashore plants in subtropical Japan: isolation, quantification and cytotoxic action of (-)-deoxypodophyllotoxin. | Phytotherapy research : PTR 20020601 |
| Effect of the DNA topoisomerase II inhibitor VP-16 on illegitimate recombination in yeast chromosomes. | Gene 20020529 |
| Antitumor agents. 213. Modeling of epipodophyllotoxin derivatives using variable selection k nearest neighbor QSAR method. | Journal of medicinal chemistry 20020523 |
| A novel combretastatin A-4 derivative, AC7700, strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organs. | British journal of cancer 20020520 |
| Antitumor and antioxidant activity of spin labeled derivatives of podophyllotoxin (GP-1) and congeners. | Life sciences 20020405 |
| Facial molluscum: treatment with cryotherapy and podophyllotoxin. | International journal of STD & AIDS 20020401 |
| Clinical inquiries. What is the most effective treatment for external genital warts? | The Journal of family practice 20020401 |
| Evaluation of Podophyllum peltatum accessions for podophyllotoxin production. | Planta medica 20020401 |
| Constitutive expression of the Id-1 promoter in human metastatic breast cancer cells is linked with the loss of NF-1/Rb/HDAC-1 transcription repressor complex. | Oncogene 20020314 |
| Synthesis and insecticidal activity of novel 4beta-halogenated benzoylamino podophyllotoxins against Pieris rapae Linnaeus. | Chemical & pharmaceutical bulletin 20020301 |
| Deoxypodophyllotoxin; the cytotoxic and antiangiogenic component from Pulsatilla koreana. | Planta medica 20020301 |
| Human T-cell leukemia virus type I Tax transactivates the matrix metalloproteinase-9 gene: potential role in mediating adult T-cell leukemia invasiveness. | Blood 20020215 |
| Positron emission tomography with [18F]2-fluoro-D-2-deoxyglucose (FDG-PET) predicts relapse of malignant lymphoma after high-dose therapy with stem cell transplantation. | Leukemia 20020201 |
| Treatment of non-Hodgkin's lymphoma in the elderly. The Italian studies. | Tumori 20020101 |
| Differential modulation by estradiol of P-glycoprotein drug resistance protein expression in cultured MCF7 and T47D breast cancer cells. | Anticancer research 20020101 |
| Optimization of culture parameters for production of podophyllotoxin in suspension culture of Podophyllum hexandrum. | Applied biochemistry and biotechnology 20020101 |
| [Incidence and management of condylomata acuminata by French general physicians]. | Annales de dermatologie et de venereologie 20020101 |
| [Management of external genital warts by dermatologists: a French survey]. | Annales de dermatologie et de venereologie 20020101 |
| [External anogenital condylomas]. | Annales de dermatologie et de venereologie 20020101 |
| Minimising the long-term adverse effects of childhood leukaemia therapy. | Drug safety 20020101 |
| [High-dose chemotherapy with autologous bone marrow transplantation in children with high-risk malignant neoformations]. | Voprosy onkologii 20020101 |
| Identification of a novel variant of the human NR2B gene promoter region and its possible association with schizophrenia. | Molecular psychiatry 20020101 |
| Analysis of the transcriptional regulation of mouse prostacyclin synthase gene. | Advances in experimental medicine and biology 20020101 |
| Drugs that inhibit tubulin polymerization: the particular case of podophyllotoxin and analogues. | Current medicinal chemistry. Anti-cancer agents 20020101 |
| Production of podophyllotoxin by plant cell cultures of Podophyllum hexandrum in bioreactor. | Journal of bioscience and bioengineering 20020101 |
| Podophyllin office therapy against condyloma should be abandoned. | Sexually transmitted infections 20011201 |
| A fast and simple GC MS method for lignan profiling in Anthriscus sylvestris and biosynthetically related Plant species. | Planta medica 20011201 |
| Factors involved in clearance of genital warts. | International journal of STD & AIDS 20011201 |
| The successful treatment of molluscum contagiosum with podophyllotoxin (0.5%) self-application. | International journal of STD & AIDS 20011201 |
| Deoxypodophyllotoxin 6-hydroxylase, a cytochrome P450 monooxygenase from cell cultures of Linum flavum involved in the biosynthesis of cytotoxic lignans. | Planta 20011201 |
| Consolidation therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of cytosine arabinoside, epipodophyllotoxins and cyclophosphamide. | Cancer treatment reviews 20011201 |
| Linker length in podophyllotoxin-acridine conjugates determines potency in vivo and in vitro as well as specificity against MDR cell lines. | Anti-cancer drug design 20011201 |
| Analytical approaches for traditional chinese medicines exhibiting antineoplastic activity. | Journal of chromatography. B, Biomedical sciences and applications 20011125 |
| Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents. | Journal of medicinal chemistry 20011108 |
| Antitumor agents 210. Synthesis and evaluation of taxoid-epipodophyllotoxin conjugates as novel cytotoxic agents. | Bioorganic & medicinal chemistry 20011101 |
| Cytogenetic analysis of human zygotes displaying three pronuclei and one polar body after intracytoplasmic sperm injection. | Human reproduction (Oxford, England) 20011101 |
| Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. | Bioorganic & medicinal chemistry letters 20011008 |
| Advances in cancer therapy with plant based natural products. | Current medicinal chemistry 20011001 |
| Considerations in the selection of an appropriate conditioning regimen for the treatment of rheumatoid arthritis by autologous peripheral blood stem cell transplantation. | The Journal of rheumatology. Supplement 20011001 |
| Immunomodulation of early engrafted natural killer cells with interleukin-2 and interferon-alpha in autologous stem cell transplantation. | Bone marrow transplantation 20011001 |
| Second malignancy after treatment of childhood non-Hodgkin lymphoma. | Cancer 20011001 |
| Silencer activity of NFATc2 in the interleukin-12 receptor beta 2 proximal promoter in human T helper cells. | The Journal of biological chemistry 20010914 |
| Aryltetralin lignans: chemistry, pharmacology and biotransformations. | Current medicinal chemistry 20010901 |
| Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. | Bioorganic & medicinal chemistry letters 20010723 |
| [PAPP-A in the first trimester of pregnancy]. | Ceska gynekologie 20010701 |
| TNF-alpha downregulates murine hepatic growth hormone receptor expression by inhibiting Sp1 and Sp3 binding. | The Journal of clinical investigation 20010601 |
| Two new podophyllotoxin glucosides from Sinopodophyllum emodi (Wall.) Ying. | Chemical & pharmaceutical bulletin 20010601 |
| New prenylated bi- and tricyclic phloroglucinol derivatives from Hypericum papuanum. | Journal of natural products 20010601 |
| A novel topoisomerase II poison GL331 preferentially induces DNA cleavage at (C/G)T sites and can cause telomere DNA damage. | Pharmaceutical research 20010601 |
| [Determination of podophyllotoxin lignans in Dysosma and its allied plants]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20010601 |
| A pancreatic beta -cell-specific enhancer in the human PDX-1 gene is regulated by hepatocyte nuclear factor 3beta (HNF-3beta ), HNF-1alpha, and SPs transcription factors. | The Journal of biological chemistry 20010518 |
| Contact dermatitis from topical antiviral drugs. | Contact dermatitis 20010501 |
| Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide. | British journal of haematology 20010501 |
| Antitumor agents. 207. Design, synthesis, and biological testing of 4beta-anilino-2-fluoro-4'-demethylpodophyllotoxin analogues as cytotoxic and antiviral agents. | Journal of medicinal chemistry 20010426 |
| Secoisolariciresinol dehydrogenase purification, cloning, and functional expression. Implications for human health protection. | The Journal of biological chemistry 20010420 |
| A phase I study in paediatric patients to evaluate the safety and pharmacokinetics of SPI-77, a liposome encapsulated formulation of cisplatin. | British journal of cancer 20010401 |
| Long-term follow-up in patients treated with Mini-BEAM as salvage therapy for relapsed or refractory Hodgkin's disease. | British journal of haematology 20010401 |
| Condyloma eradication: self-therapy with 0.15-0.5% podophyllotoxin versus 20-25% podophyllin preparations--an integrated safety assessment. | Regulatory toxicology and pharmacology : RTP 20010401 |
| Cytotoxic cyclolignans related to podophyllotoxin. | Farmaco (Societa chimica italiana : 1989) 20010401 |
| Antitumor agents. Synthesis and biological evaluation of new compounds related to podophyllotoxin, containing the 2,3-dihydro-1,4-benzodioxin system. | European journal of medicinal chemistry 20010401 |
| Direct medical costs for surgical and medical treatment of condylomata acuminata. | Archives of dermatology 20010301 |
| The production of cytotoxic lignans by plant cell cultures. | Applied microbiology and biotechnology 20010301 |
| High yield of podophyllotoxin from leaves of Podophyllum peltatum by in situ conversion of podophyllotoxin 4- O-beta-D-glucopyranoside. | Planta medica 20010201 |
| Podophyllotoxin lignans enhance IL-1beta but suppress TNF-alpha mRNA expression in LPS-treated monocytes. | Immunopharmacology and immunotoxicology 20010201 |
| The treatment of anogenital warts at home. | Nursing times 20010201 |
| [Synthesis and activities of 4-deoxy-4 beta-arylmehtylene sulfonylamido-4'-demethylpodophyllotoxins]. | Yao xue xue bao = Acta pharmaceutica Sinica 20010201 |
| Cytotoxic responses to aromatic ring and configurational variations in alpha-conidendrin, podophyllotoxin, and sikkimotoxin derivatives. | Journal of medicinal chemistry 20010118 |
| GATA-4 and serum response factor regulate transcription of the muscle-specific carnitine palmitoyltransferase I beta in rat heart. | The Journal of biological chemistry 20010112 |
| [Clinical aspects and therapy of anogenital warts and papillomavirus-associated lesions]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20010101 |
| Issues and practicalities of treating genital warts in the community. Proceedings of a round table meeting facilitated by Succinct Communications Limited. | International journal of STD & AIDS 20010101 |
| Imiquimod for the treatment of genital warts: a quantitative systematic review. | BMC infectious diseases 20010101 |
| Prevention and management of antineoplastic-induced hypersensitivity reactions. | Drug safety 20010101 |
| Management of anogenital warts (condylomata acuminata). | European journal of dermatology : EJD 20010101 |
| Treatment of anogenital warts in children with topical 0.05% podofilox gel and 5% imiquimod cream. | Pediatric dermatology 20010101 |
| [Myelotoxicity of a plant cytostatic preparation etoposide]. | Eksperimental'naia i klinicheskaia farmakologiia 20010101 |
| Enhanced podophyllotoxin production from Agrobacterium rhizogenes transformed cultures of Podophyllum hexandrum. | Natural product letters 20010101 |
| Accumulation of lignans in suspension cultures of Linum mucronatum ssp. armenum (Bordz.) Davis. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101 |
| Communication challenges in a young man with Hodgkin's disease. | Cancer practice 20010101 |
| 6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization. | Journal of medicinal chemistry 20001116 |
| TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia. | Blood 20000801 |
| Podophyllotoxin. | Phytochemistry 20000501 |
| Sensory neuropathy due to Bajiaolian (Podophyllotoxin) intoxication. | European neurology 20000101 |
| Inhibitory effects of podophyllotoxin derivatives on herpes simplex virus replication. | Antiviral chemistry & chemotherapy 19980501 |
| Discovery of podophyllotoxins. | Biochimie 19980301 |
| Navoban (tropisetron, ICS 205-930) and dexamethasone combination in the prevention of vomiting for patients receiving preconditioning high-dose chemotherapy before marrow transplantation. | Japanese journal of clinical oncology 19980201 |
| Safety and efficacy of 0.5% podofilox gel in the treatment of anogenital warts. | Archives of dermatology 19980101 |
| Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent. | Cancer research 19970815 |
| Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids. | Carcinogenesis 19960301 |
| Differential in vitro anti-HIV activity of natural lignans. | Zeitschrift fur Naturforschung. C, Journal of biosciences 19900101 |
| Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study. | Molecular pharmacology 19880801 |
| Etoposide-induced hypersensitivity reactions. Report of two cases. | Chemioterapia : international journal of the Mediterranean Society of Chemotherapy 19851201 |
| Transient heart block. An unreported toxicity of high dose chemotherapy with cyclophosphamide and etoposide. | Acta clinica Belgica 19850101 |
| High-dose etoposide for refractory malignancies: a phase I study. | Cancer treatment reports 19841201 |
| Tumor lysis syndrome following VP-16-213 in chronic myeloid leukemia in blast crisis. | American journal of hematology 19840201 |
| Lack of potentiation of vincristine-induced neurotoxicity by VP-16-213. | American journal of clinical oncology 19830601 |
| Possible enhancement of vincristine neuropathy by VP-16. | Cancer 19820301 |
| A phase I trial of continuous infusion VP16-213 (etoposide). | Cancer chemotherapy and pharmacology 19820101 |
| Combined VM-26 and cytosine arabinoside in treatment of refractory childhood lymphocytic leukemia. | Cancer 19800315 |
| Prophylaxis of bladder tumor implantation. Intravesical and systemic chemotherapy. | Urology 19760101 |
| 4'-demethyl-epipodophyllotoxin-beta-D-thenylidene glucoside (VM-26)--a brief review. | European journal of cancer 19730701 |