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Tropolone

CAS No.:
533-75-5
Catalog Number:
AG003ACI
Molecular Formula:
C7H6O2
Molecular Weight:
122.1213
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$13
- +
5g
95%
In Stock USA
United States
$30
- +
25g
98%
In Stock USA
United States
$105
- +
100g
98%
In Stock USA
United States
$300
- +
Product Description
Catalog Number:
AG003ACI
Chemical Name:
Tropolone
CAS Number:
533-75-5
Molecular Formula:
C7H6O2
Molecular Weight:
122.1213
MDL Number:
MFCD00004158
IUPAC Name:
2-hydroxycyclohepta-2,4,6-trien-1-one
InChI:
InChI=1S/C7H6O2/c8-6-4-2-1-3-5-7(6)9/h1-5H,(H,8,9)
InChI Key:
MDYOLVRUBBJPFM-UHFFFAOYSA-N
SMILES:
Oc1cccccc1=O
EC Number:
208-577-2
UNII:
7L6DL16P1T
NSC Number:
89303
Properties
Complexity:
209  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
122.037g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
122.123g/mol
Monoisotopic Mass:
122.037g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
37.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.5  
Literature
Title Journal
Synthesis and biological assessment of 3,7-dihydroxytropolones. Organic & biomolecular chemistry 20171219
Hinokitiol induces autophagy in murine breast and colorectal cancer cells. Environmental toxicology 20160101
The furan route to tropolones: probing the antiproliferative effects of β-thujaplicin analogs. Organic & biomolecular chemistry 20121121
Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs. Biochemical pharmacology 20121101
Synthesis and electrochemistry of organometallic cobaltadithiaazulenes. Inorganic chemistry 20121015
Detection of natural and induced phenoloxidase activities in human serum. Human immunology 20121001
Transport of the anti-diabetic VO2+ complexes formed by pyrone derivatives in the blood serum. Journal of inorganic biochemistry 20121001
Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis. Proceedings of the National Academy of Sciences of the United States of America 20120515
Pycnidione, a fungus-derived agent, induces cell cycle arrest and apoptosis in A549 human lung cancer cells. Chemico-biological interactions 20120415
5-(Phenyl-diazen-yl)tropolone. Acta crystallographica. Section E, Structure reports online 20120401
Characterization of melanin pigment produced by Aspergillus nidulans. World journal of microbiology & biotechnology 20120401
In vitro and in vivo anti-plasmodial activity of essential oils, including hinokitiol. The Southeast Asian journal of tropical medicine and public health 20120301
1-(3-Hy-droxy-phen-yl)-3-(3-meth-oxy-phenyl)thio-urea. Acta crystallographica. Section E, Structure reports online 20120201
Potentiation of bleomycin in Jurkat cells by fungal pycnidione. Biological & pharmaceutical bulletin 20120101
Effects of a combination of hinokitiol (β-thujaplicin) and an organic acid mixture on ruminal fermentation in heifers fed a high-grain diet. Animal science journal = Nihon chikusan Gakkaiho 20120101
Hybrid SPECT/cardiac-gated first-pass perfusion CT: locating transplanted cells relative to infarcted myocardial targets. Contrast media & molecular imaging 20120101
Exploitation of lipid components by viral and host proteins for hepatitis C virus infection. Frontiers in microbiology 20120101
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Preventive effects of β-thujaplicin against UVB-induced MMP-1 and MMP-3 mRNA expressions in skin fibroblasts. The American journal of Chinese medicine 20120101
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Effects of known phenoloxidase inhibitors on hemocyanin-derived phenoloxidase from Limulus polyphemus. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120101
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1-[3-(Hy-droxy-meth-yl)phen-yl]-3-phenyl-urea. Acta crystallographica. Section E, Structure reports online 20110801
Synthesis, activity, and structural analysis of novel α-hydroxytropolone inhibitors of human immunodeficiency virus reverse transcriptase-associated ribonuclease H. Journal of medicinal chemistry 20110714
Solid-state thiotropolone: an extremely rapid intramolecular proton transfer. The Journal of organic chemistry 20110701
Crystal structure of Agaricus bisporus mushroom tyrosinase: identity of the tetramer subunits and interaction with tropolone. Biochemistry 20110621
Identification, structural properties and chelating capacity of miltipolone as a broad-spectrum inhibitor to cancer cells. European journal of medicinal chemistry 20110401
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Identifying chelators for metalloprotein inhibitors using a fragment-based approach. Journal of medicinal chemistry 20110127
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Antiviral drugs against hepatitis C virus. Genetic vaccines and therapy 20110101
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Modeling natural anti-inflammatory compounds by molecular topology. International journal of molecular sciences 20110101
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A colored avocado seed extract as a potential natural colorant. Journal of food science 20110101
Computational study of the intramolecular proton transfer reactions of 3-hydroxytropolone (2,7-dihydroxycyclohepta-2,4,6-trien-1-one) and its dimers. Journal of molecular modeling 20101201
Inhibitory effects of hinokitiol on tyrosinase activity and melanin biosynthesis and its antimicrobial activities. Journal of enzyme inhibition and medicinal chemistry 20101201
Bis[2-(methyl-amino)-troponato]copper(II). Acta crystallographica. Section E, Structure reports online 20101201
1-(4-Hy-droxy-phen-yl)-3-(3,4,5-tri-methoxy-phen-yl)thio-urea. Acta crystallographica. Section E, Structure reports online 20101201
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Structural insights into the hot spot amino acid residues of mushroom tyrosinase for the bindings of thujaplicins. Bioorganic & medicinal chemistry 20101115
A microwave study of hydrogen-transfer-triggered methyl-group rotation in 5-methyltropolone. The Journal of chemical physics 20101114
catena-Poly[(μ(3)-2-hy-droxy-4-isopropyl-cyclo-hepta-2,4,6-trien-1-onato)(μ(2)-2-hy-droxy-4-isopropyl-cyclo-hepta-2,4,6-trien-1-onato)lead(II)]. Acta crystallographica. Section E, Structure reports online 20101101
1-(2-Hy-droxy-eth-yl)-3-(3-meth-oxy-phen-yl)thio-urea. Acta crystallographica. Section E, Structure reports online 20101001
Vibrational specificity of proton-transfer dynamics in ground-state tropolone. Physical chemistry chemical physics : PCCP 20100801
Studies on the anti-hepatitis C virus activity of newly synthesized tropolone derivatives: identification of NS3 helicase inhibitors that specifically inhibit subgenomic HCV replication. Bioorganic & medicinal chemistry 20100715
Tetra-ethyl-ammonium bromidotricarbon-yl(tropolonato)rhenate(I). Acta crystallographica. Section E, Structure reports online 20100701
Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice. PLoS biology 20100601
Hinokitiol activates the hypoxia-inducible factor (HIF) pathway through inhibition of HIF hydroxylases. Biochemical and biophysical research communications 20100528
In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. Drug development and industrial pharmacy 20100501
Time-kill assay results for a linalool-hinokitiol-based eyelid cleanser for lid hygiene. Cornea 20100501
Rational design and synthesis of 4-o-substituted phenylmethylenethiosemicarbazones as novel tyrosinase inhibitors. Chemical & pharmaceutical bulletin 20100501
Impact of protein on darkening in yellow alkaline noodles. Journal of agricultural and food chemistry 20100414
First evidence of laccase activity in the Pacific oyster Crassostrea gigas. Fish & shellfish immunology 20100401
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HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors. Viruses 20100401
Development of the extraction method for the simultaneous determination of butyl-, phenyl- and octyltin compounds in sewage sludge. Talanta 20100315
Structural, electronic and magnetic properties of Cu(II) complexes of 2-substituted tropones bearing a ferrocenyl group at 5-position. Dalton transactions (Cambridge, England : 2003) 20100307
Serial in vivo imaging of the porcine heart after percutaneous, intramyocardially injected 111In-labeled human mesenchymal stromal cells. The international journal of cardiovascular imaging 20100301
Synthesis of tropolone derivatives and evaluation of their in vitro neuroprotective activity. European journal of medicinal chemistry 20100301
Comparison of initial cell retention and clearance kinetics after subendocardial or subepicardial injections of endothelial progenitor cells in a canine myocardial infarction model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100301
Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes. Metallomics : integrated biometal science 20100301
Biomimetic formation of 2-tropolones by dioxygenase-catalysed ring expansion of substituted 2,4-cyclohexadienones. Chembiochem : a European journal of chemical biology 20100125
Identification and biosynthesis of tropone derivatives and sulfur volatiles produced by bacteria of the marine Roseobacter clade. Organic & biomolecular chemistry 20100107
Novel synthesis of ureas: application of t-butylureas. Chemical & pharmaceutical bulletin 20100101
Hormetic response of cultured normal and tumor cells to 2-aminotropone derivatives. In vivo (Athens, Greece) 20100101
Quantitative structure-cytotoxicity relationship of newly synthesized tropolones determined by a semiempirical molecular-orbital method (PM5). Anticancer research 20100101
Hormetic and anti-radiation effects of tropolone-related compounds. In vivo (Athens, Greece) 20100101
New strategies for the treatment of hepatitis C virus infection and implications of resistance to new direct-acting antiviral agents. Infection and drug resistance 20100101
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Benzo[cd]azulene skeleton: azulene, heptafulvene, and tropone derivatives. Organic letters 20091203
Microwave spectrum of the argon-tropolone van der Waals complex. The journal of physical chemistry. A 20091126
Dissection of rovibronic structure by polarization-resolved two-color resonant four-wave mixing spectroscopy. The journal of physical chemistry. A 20091126
Discovery of 4-functionalized phenyl-O-beta-D-glycosides as a new class of mushroom tyrosinase inhibitors. Bioorganic & medicinal chemistry letters 20091101
Examination of DFT and TDDFT methods II. The journal of physical chemistry. A 20091015
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Access to a welwitindolinone core using sequential cycloadditions. Organic letters 20090820
Concerted action of the cytosolic sulfotransferase, SULT1A3, and catechol-O-methyltransferase in the metabolism of dopamine in SK-N-MC human neuroblastoma cells. Neuroscience research 20090701
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Physical-chemical analysis of non-polyphenol oxidase (non-PPO) darkening in yellow alkaline noodles. Journal of agricultural and food chemistry 20090624
In vivo SPECT quantification of transplanted cell survival after engraftment using (111)In-tropolone in infarcted canine myocardium. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090601
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Chiral photochemistry within a confined space: diastereoselective photorearrangements of a tropolone and a cyclohexadienone included in a synthetic cavitand. Dalton transactions (Cambridge, England : 2003) 20090528
Volatile and non-volatile monoterpenes produced by elicitor-stimulated Cupressus lusitanica cultured cells. Journal of plant physiology 20090501
Detection of phenoloxidase activity in early stages of the Pacific oyster Crassostrea gigas (Thunberg). Developmental and comparative immunology 20090501
Pernambucone, a new tropone derivative from Croton argyroglossum. Die Pharmazie 20090501
Theoretical study of proton tunneling in the excited state of tropolone. The Journal of chemical physics 20090428
An exploration of electronic structure and nuclear dynamics in tropolone: II. The A (1)B2 (pi* pi) excited state. The Journal of chemical physics 20090414
A class of potent tyrosinase inhibitors: alkylidenethiosemicarbazide compounds. European journal of medicinal chemistry 20090401
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Bis(triphenyl-phosphine-κP)(tropolonato-κO,O')silver(I) dichloro-methane solvate. Acta crystallographica. Section E, Structure reports online 20090201
Ring-expansion protocol: preparation of synthetically versatile dihydrotropones. The Journal of organic chemistry 20090116
Targeting mitochondrial permeability in cancer drug development. Molecular nutrition & food research 20090101
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The prophenoloxidase system is activated during the tunic inflammatory reaction of Ciona intestinalis. Cell and tissue research 20080901
A wounding-induced PPO from cowpea (Vigna unguiculata) seedlings. Phytochemistry 20080901
High production of beta-thujaplicin glycosides by immobilized plant cells of Nicotiana tabacum. Acta biologica Hungarica 20080901
Enhanced stereoselectivity in photoelectrocyclization of tropolone ethers via confinement in chiral inductor-modified lyotropic liquid crystals. Organic letters 20080821
In vivo hair growth promotion effects of cosmetic preparations containing hinokitiol-loaded poly(epsilon-caprolacton) nanocapsules. Journal of microencapsulation 20080801
Antifungal properties of ethanolic extract and its active compounds from Calocedrus macrolepis var. formosana (Florin) heartwood. Bioresource technology 20080701
Aminotroponiminate calcium and strontium complexes. Dalton transactions (Cambridge, England : 2003) 20080607
Electronic modification of an aminotroponiminate zinc complex leading to an increased reactivity in the hydroamination of alkenes. Dalton transactions (Cambridge, England : 2003) 20080607
Hinokitiol, a natural tropolone derivative, inhibits TNF-alpha production in LPS-activated macrophages via suppression of NF-kappaB. Planta medica 20080601
Tetra-kis(1,1,1-trifluoro-acetyl-acetonato-κO,O')zirconium(IV) toluene solvate. Acta crystallographica. Section E, Structure reports online 20080601
[Analysis the pollution level of organotins in aquatic food and port wine]. Wei sheng yan jiu = Journal of hygiene research 20080501
Crototropone, a new tropone derivative from Croton zehntneri. Fitoterapia 20080401
Antifungal mechanism of hinokitiol against Candida albicans. Biological & pharmaceutical bulletin 20080401
On the sulfation and methylation of catecholestrogens in human mammary epithelial cells and breast cancer cells. Biological & pharmaceutical bulletin 20080401
Noreupenifeldin, a tropolone from an unidentified ascomycete. Journal of natural products 20080301
Agglutinin-mediated phagocytosis-associated generation of superoxide anion and nitric oxide by the hemocytes of the giant freshwater prawn Macrobrachium rosenbergii. Fish & shellfish immunology 20080301
Tunneling splittings for 'O...O stretching' and other vibrations of tropolone isotopomers observed in the infrared spectrum below 800 cm(-1). The journal of physical chemistry. A 20080221
A fresh look at natural tropolonoids. Natural product reports 20080201
1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors. Bioorganic & medicinal chemistry 20080201
pH-dependent inhibition of mushroom tyrosinase by N-substituted N-nitrosohydroxylamines. Journal of enzyme inhibition and medicinal chemistry 20080201
Computational studies of the tropone natural products, thiotropocin, tropodithietic acid, and troposulfenin. Significance of thiocarbonyl-enol tautomerism. The Journal of organic chemistry 20080104
Synthesis of 4-aminotropones from [(sulfinyl or sulfonyl)methyl]-substituted p-quinamines. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Imaging of gene expression in live pancreatic islet cell lines using dual-isotope SPECT. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080101
In vitro permeation study of hinokitiol: effects of vehicles and enhancers. Drug delivery 20080101
Bonding in tropolone, 2-aminotropone, and aminotroponimine: no evidence of resonance-assisted hydrogen-bond effects. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Polyphenol oxidase from wheat bran is a serpin. Acta biochimica Polonica 20080101
Crystal structures of 2-aminotropone, n,n'-di(tropon-2-yl)piperazine, and 5-(4-ethoxyphenylazo)tropolone. Journal of oleo science 20080101
A strategy to protect and sensitize near-infrared luminescent Nd3+ and Yb3+: organic tropolonate ligands for the sensitization of Ln(3+)-doped NaYF4 nanocrystals. Journal of the American Chemical Society 20071205
Synthesis and in vitro protozoocidal evaluation of novel diazabicyclic tropolone derivatives. Archiv der Pharmazie 20071101
Tolerance to Bacillus thuringiensis endotoxin in immune-suppressed larvae of the flour moth Ephestia kuehniella. Journal of invertebrate pathology 20071001
Melanin biosynthesis by Frankia strain CeI5. Physiologia plantarum 20071001
The mechanism of the bactericidal activity of hinokitiol. Biocontrol science 20070901
Mode-specific tunneling dynamics in the ground electronic state of tropolone. The Journal of chemical physics 20070828
A new access to dihydrotropones through ring expansion of spirocyclohexadienones: synthesis and mechanism. The Journal of organic chemistry 20070817
Growth inhibitory effect of shelf life extending agents on Bacillus subtilis IAM 1026. Biocontrol science 20070601
Cytotoxicity of colchicine derivatives in primary cultures of human hepatocytes. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20070601
Influence of pH and counteranion on the structure of tropolonato-lead(II) complexes: structural and infrared characterization of formed lead compounds. Inorganic chemistry 20070528
Three-coordinated aminotroponiminate and aminotroponate complexes of gold(I). Inorganic chemistry 20070528
Value of zeolites in asymmetric induction during photocyclization of pyridones, cyclohexadienones and naphthalenones. Organic & biomolecular chemistry 20070521
Optimisation of pressurised liquid extraction for elimination of sulphur interferences during determination of organotin compounds in sulphur-rich sediments by gas chromatography with flame photometric detection. Chemosphere 20070501
Certification of butyltins and phenyltins in marine sediment certified reference material by species-specific isotope-dilution mass spectrometric analysis using synthesized 118Sn-enriched organotin compounds. Analytical and bioanalytical chemistry 20070401
Demonstration of a true phenoloxidase activity and activation of a ProPO cascade in Pacific oyster, Crassostrea gigas (Thunberg) in vitro. Fish & shellfish immunology 20070401
UV-visible and 1H or 13C NMR spectroscopic studies on the specific interaction between lithium ions and the anion from tropolone or 4-isopropyltropolone (hinokitiol) and on the formation of protonated tropolones in acetonitrile or other solvents. The journal of physical chemistry. B 20070222
Tropolone and its derivatives as inhibitors of the helicase activity of hepatitis C virus nucleotide triphosphatase/helicase. Antiviral chemistry & chemotherapy 20070101
Reactive oxygen species, nitric oxide, and their interactions play different roles in Cupressus lusitanica cell death and phytoalexin biosynthesis. The New phytologist 20070101
Kinetic radical-scavenging activity of colchicine and tropolone. In vivo (Athens, Greece) 20070101
Plant troponoids: chemistry, biological activity, and biosynthesis. Current medicinal chemistry 20070101
A novel function for selenium in biological system: selenite as a highly effective iron carrier for Chinese hamster ovary cell growth and monoclonal antibody production. Biotechnology and bioengineering 20061220
Hinokitiol, a metal chelator derived from natural plants, suppresses cell growth and disrupts androgen receptor signaling in prostate carcinoma cell lines. Biochemical and biophysical research communications 20061208
Labelling of human mesenchymal stem cells with indium-111 for SPECT imaging: effect on cell proliferation and differentiation. European journal of nuclear medicine and molecular imaging 20061001
Lack of hinokitiol (beta-thujaplicin) carcinogenicity in F344/DuCrj rats. The Journal of toxicological sciences 20061001
Determination of tributyltin and 4-hydroxybutyldibutyltin chlorides in seawater by liquid chromatography with atmospheric pressure chemical ionization-mass spectrometry. Analytica chimica acta 20060925
Differential regulation of melanosomal proteins after hinokitiol treatment. Journal of dermatological science 20060901
Quantum tunneling in the midrange vibrational fundamentals of tropolone. The journal of physical chemistry. A 20060810
The design of organic catalysis for epoxidation by hydrogen peroxide. Journal of molecular modeling 20060701
Raman spectroscopic studies on tropolone complexes with La, Nd, Sm, Yb. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060701
The excellence of Aomori Hiba (Hinokiasunaro) in its use as building materials of Buddhist temples and Shinto shrines. Biocontrol science 20060601
An exploration of electronic structure and nuclear dynamics in tropolone. I. The X 1A1 ground state. The Journal of chemical physics 20060528
The conformational state of polyphenol oxidase from field bean (Dolichos lablab) upon SDS and acid-pH activation. The Biochemical journal 20060501
Preferential inhibition of the magnesium-dependent strand transfer reaction of HIV-1 integrase by alpha-hydroxytropolones. Molecular pharmacology 20060401
Therapeutic effects of beta-thujaplicin eardrops on canine Malassezia-related otitis externa. The Journal of veterinary medical science 20060401
Delineating the role of polyphenol oxidase in the darkening of alkaline wheat noodles. Journal of agricultural and food chemistry 20060322
Searching for a new anti-HCV therapy: synthesis and properties of tropolone derivatives. Biochemical and biophysical research communications 20060310
High-resolution studies of tropolone in the S0 and S1 electronic states: isotope driven dynamics in the zero-point energy levels. The Journal of chemical physics 20060221
Isoelectronic homologues and isomers: tropolone, 5-azatropolone, 1-H-azepine-4,5-dione, saddle points, and ions. The journal of physical chemistry. A 20060202
Signal transduction and metabolic flux of beta-thujaplicin and monoterpene biosynthesis in elicited Cupressus lusitanica cell cultures. Metabolic engineering 20060101
Human metallothionein gene expression is upregulated by beta-thujaplicin: possible involvement of protein kinase C and reactive oxygen species. Biological & pharmaceutical bulletin 20060101
Relationship between electronic structure and cytotoxic activity of tropolones. In vivo (Athens, Greece) 20060101
Colchitaxel, a coupled compound made from microtubule inhibitors colchicine and paclitaxel. Beilstein journal of organic chemistry 20060101
In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators. Kinetoplastid biology and disease 20060101
Production of sepedonin by Sepedonium chrysospermum NT-1 in submerged culture. Environmental sciences : an international journal of environmental physiology and toxicology 20060101
Arachidonate 12-lipoxygenases with reference to their selective inhibitors. Biochemical and biophysical research communications 20051209
Inhibition of human immunodeficiency virus type 1 reverse transcriptase, RNase H, and integrase activities by hydroxytropolones. Antimicrobial agents and chemotherapy 20051201
Inhibitory effects of 4-n-butylresorcinol on tyrosinase activity and melanin synthesis. Biological & pharmaceutical bulletin 20051201
Prooxidant action of hinokitiol: hinokitiol-iron dependent generation of reactive oxygen species. Basic & clinical pharmacology & toxicology 20051201
Effects of beta-thujaplicin on anti-Malassezia pachydermatis remedy for canine otitis externa. The Journal of veterinary medical science 20051201
Mosquito larvicidal activity of active constituent derived from Chamaecyparis obtusa leaves against 3 mosquito species. Journal of the American Mosquito Control Association 20051201
Efforts directed toward the synthesis of colchicine: application of palladium-catalyzed siloxane cross-coupling methodology. The Journal of organic chemistry 20051028
Determining the minimum number of detectable cardiac-transplanted 111In-tropolone-labelled bone-marrow-derived mesenchymal stem cells by SPECT. Physics in medicine and biology 20051007
Sgk1, a cell survival response in neurodegenerative diseases. Molecular and cellular neurosciences 20051001
Potential antimalarial lead structures from fungi of marine origin. Planta medica 20051001
Total synthesis of (-)-colchicine via a Rh-triggered cycloaddition cascade. Organic letters 20050929
Oxidation of the flavonoid eriodictyol by tyrosinase. Plant physiology and biochemistry : PPB 20050901
Role of cations and confinement in asymmetric photochemistry: enantio- and diastereo-selective photocyclization of tropolone derivatives within zeolites. Organic & biomolecular chemistry 20050821
The all-Cartesian reaction plane Hamiltonian: formulation and application to the H-atom transfer in tropolone. The Journal of chemical physics 20050801
Polyphenol oxidase from Dominga table grape. Journal of agricultural and food chemistry 20050727
Activation of catechol-O-methyltransferase in astrocytes stimulates homocysteine synthesis and export to neurons. Glia 20050701
18O effects on the infrared spectrum and skeletal tunneling of tropolone. The Journal of chemical physics 20050608
Oxidative stress in plant cell culture: a role in production of beta-thujaplicin by Cupresssus lusitanica suspension culture. Biotechnology and bioengineering 20050605
Development of Animal-free, Protein-Free and Chemically-Defined Media for NS0 Cell Culture. Cytotechnology 20050601
Six-coordinate titanium complexes of a tripodal aminetris(phenoxide) ligand: synthesis, structure, and dynamics. Inorganic chemistry 20050418
Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies. Bioorganic & medicinal chemistry 20050401
Acaricidal activity of active constituent isolated in Chamaecyparis obtusa leaves against Dermatophagoides spp. Journal of agricultural and food chemistry 20050323
Implications of comparative spectral doublets observed for neon-isolated and gaseous tropolone(OH) and tropolone(OD). The Journal of chemical physics 20050322
Dynamical hydrogen atom tunneling in dichlorotropolone: a combined quantum, semiclassical, and classical study. The Journal of chemical physics 20050322
Ring expansion of sulfur substituted p-quinamines: regiospecific synthesis of 4-aminotropones. Chemical communications (Cambridge, England) 20050227
Methyl group rotation driven by proton transfer through a long-range chemical interaction. Angewandte Chemie (International ed. in English) 20050211
Characterization and purification of polyphenol oxidase from artichoke (Cynara scolymus L.). Journal of agricultural and food chemistry 20050209
Protection by tropolones against H2O2-induced DNA damage and apoptosis in cultured Jurkat cells. Free radical research 20050201
Fungal diversity from western redcedar fences and their resistance to beta-thujaplicin. Antonie van Leeuwenhoek 20050201
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones. Nucleic acids research 20050101
Anticholinesterase efficiency of some tropolone alkaloids and their lumiderivatives. Doklady. Biochemistry and biophysics 20050101
Biological activity of beta-dolabrin, gamma-thujaplicin, and 4-acetyltropolone, hinokitiol-related compounds. Biological & pharmaceutical bulletin 20041001
Polarization spectroscopy of gaseous tropolone in a strong electric field. The Journal of chemical physics 20040908
Cerebral neutrophil recruitment, histology, and outcome in acute ischemic stroke: an imaging-based study. Stroke 20040701
Biological activity of alpha-thujaplicin, the isomer of hinokitiol. Biological & pharmaceutical bulletin 20040601
Rapid accumulation and metabolism of polyphosphoinositol and its possible role in phytoalexin biosynthesis in yeast elicitor-treated Cupressus lusitanica cell cultures. Planta 20040501
Jasmonate and ethylene signalling and their interaction are integral parts of the elicitor signalling pathway leading to beta-thujaplicin biosynthesis in Cupressus lusitanica cell cultures. Journal of experimental botany 20040501
Liquid chromatography-hydride generation-atomic absorption spectrometry for the speciation of tin in seafoods. Journal of environmental monitoring : JEM 20040401
Beta-thujaplicin: new quantitative CZE method and adsorption to goethite. Journal of agricultural and food chemistry 20040324
Time-dependent probability of quantum tunneling in terms of the quasisemiclassical method. The Journal of chemical physics 20040308
Rotation-tunneling analysis of the origin band in the tropolone pi(*)<--pi absorption system. The Journal of chemical physics 20040308
Determination of organotin compounds in biological samples using accelerated solvent extraction, sodium tetraethylborate ethylation, and multicapillary gas chromatography-flame photometric detection. Analytical and bioanalytical chemistry 20040301
Evaluation of developmental toxicity of beta-thujaplicin (hinokitiol) following oral administration during organogenesis in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040301
(-)-Epigallocatechin-3-gallate and hinokitiol reduce melanin synthesis via decreased MITF production. Archives of pharmacal research 20040301
Synthesis and structural characterization of silver(I), aluminium(III) and cobalt(II) complexes with 4-isopropyltropolone (hinokitiol) showing noteworthy biological activities. Action of silver(I)-oxygen bonding complexes on the antimicrobial activities. Journal of inorganic biochemistry 20040101
Transmission electron microscopy of Schistosoma mansoni cercariae treated with hinokitiol (beta-thujaplicin), a compound for potential skin application against cercarial penetration. The Tohoku journal of experimental medicine 20040101
Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines. Anticancer research 20040101
Comparison of tropane alkaloid spectra between Datura innoxia grown in Egypt and Bulgaria. Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by tropolones. Anticancer research 20040101
[Antimicrobial activity of hinokitiol against Legionella pneumophila]. Journal of UOEH 20031201
Biological activity of tropolone. Biological & pharmaceutical bulletin 20031001
Generation of reactive oxygen species from Hinokitiol under near-UV irradiation. Bioscience, biotechnology, and biochemistry 20030901
Carbon-13 CP-MAS nuclear magnetic resonance studies of teas. Solid state nuclear magnetic resonance 20030501
Butyltin compounds in retail mollusc products. Food additives and contaminants 20030501
Seasonal and spatial variations of alkaloids in Merendera montana in relation to chemical defense and phenology. Journal of chemical ecology 20030501
Partial purification of latent persimmon fruit polyphenol oxidase. Journal of agricultural and food chemistry 20030326
Adhesion of endometrial cells labeled with 111Indium-tropolonate to peritoneum: a novel in vitro model to study endometriosis. Fertility and sterility 20030301
Multiple signalling pathways mediate fungal elicitor-induced beta-thujaplicin biosynthesis in Cupressus lusitanica cell cultures. Journal of experimental botany 20030201
Low-level iron-dependent mutants of Listeria monocytogenes and their virulence in macrophages. Canadian journal of microbiology 20030201
Antibacterial effect of beta-thujaplicin on staphylococci isolated from atopic dermatitis: relationship between changes in the number of viable bacterial cells and clinical improvement in an eczematous lesion of atopic dermatitis. The Journal of antimicrobial chemotherapy 20030101
Actions of U-92032, a T-type Ca2+ channel antagonist, support a functional linkage between I(T) and slow intrathalamic rhythms. Journal of neurophysiology 20030101
Improved fermentation processes for NS0 cell lines expressing human antibodies and glutamine synthetase. Biotechnology progress 20030101
Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. European journal of medicinal chemistry 20030101
Cytotoxic activity of tropolones against human oral tumor cell lines. Anticancer research 20030101
Tyrosinase-mediated oxidation of acetaminophen to 4-acetamido-o-benzoquinone. Biological chemistry 20021201
Biomimetic cycloaddition approach to tropolone natural products via a tropolone ortho-quinone methide. Organic letters 20020822
Biological activity of 4-acetyltropolone, the minor component of Thujopsis dolabrata SIeb. et Zucc. hondai Mak. Biological & pharmaceutical bulletin 20020801
One-step stereoselective synthesis and NMR chiral shift properties of a novel hexacoordinated phosphorus cation. Organic letters 20020711
Feedback regulation of beta-thujaplicin production and formation of its methyl ether in a suspension culture of Cupressus lusitanica. Phytochemistry 20020701
Enantioselective photoreaction of achiral tropolone ether in inclusion crystals with optically active host compounds. Chirality 20020701
Synthesis of new azulene derivatives and study of their effect on lipid peroxidation and lipoxygenase activity. Chemical & pharmaceutical bulletin 20020701
Selective preconcentration and determination of tributyltin in fresh water by electrothermal atomic absorption spectrometry. Analytical and bioanalytical chemistry 20020401
Role of tyrosinase in the genoprotective effect of the edible mushroom, Agaricus bisporus. Life sciences 20020222
Diagnostic value of (111)In-granulocyte scintigraphy in patients with fever of unknown origin. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020201
Application of Lewis acid catalyzed tropone [6+4] cycloadditions to the synthesis of the core of CP-225,917. Organic letters 20011227
Crossover phase behavior (discotic to calamitic) in liquid-crystalline copper complexes. Dependence on the length and position of alkoxy chains in new polycatenar bis[5-(dialkoxybenzylidine)aminotropololonato]copper(II) complexes. Inorganic chemistry 20011203
The impact of recent advances in immunology and cancer therapy on nuclear medicine. Seminars in nuclear medicine 20011001
Abnormal platelet adhesion on abdominal vessels in asymptomatic patients with paroxysmal nocturnal hemoglobinuria. Annals of hematology 20011001
Fungicidal activity of beta-thujaplicin analogues. Pest management science 20010901
A new tropolone from the insect pathogenic fungus Cordyceps sp. BCC 1681. The Journal of antibiotics 20010901
Synthesis and structural characterization of tin(II) and zinc(II) derivatives of cyclic alpha-hydroxyketones, including the structures of Sn(maltol)(2), Sn(tropolone)(2), Zn(tropolone)(2), and Zn(hinokitiol)(2). Inorganic chemistry 20010813
Cytotoxic effects of beta-thujaplicin on rat thymocytes and prevention by the compound in tributyltin-induced thymocyte damage. Bulletin of environmental contamination and toxicology 20010701
Hydroxy- or methoxy-substituted benzaldoximes and benzaldehyde-O-alkyloximes as tyrosinase inhibitors. Bioorganic & medicinal chemistry 20010701
Biological activity of alpha-thujaplicin, the minor component of Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO. Biological & pharmaceutical bulletin 20010601
Synthesis and biological evaluation of O-alkylated tropolones and related alpha-ketohydroxy derivatives as ribonucleotide reductase inhibitors. European journal of medicinal chemistry 20010601
Synthesis of N-substituted N-nitrosohydroxylamines as inhibitors of mushroom tyrosinase. Bioorganic & medicinal chemistry 20010501
Production of beta-thujaplicin in Cupressus lusitanica suspension cultures fed with organic acids and monoterpenes. Bioscience, biotechnology, and biochemistry 20010501
Total synthesis of tropoloisoquinolines: imerubrine, isoimerubrine, and grandirubrine. Journal of the American Chemical Society 20010411
Partial purification, characterization, and histochemical localization of fully latent desert truffle (Terfezia claveryi Chatin) polyphenol oxidase. Journal of agricultural and food chemistry 20010401
Novel retinoidal tropolone derivatives. Bioisosteric relationship of tropolone ring with benzoic acid moiety in retinoid structure. Chemical & pharmaceutical bulletin 20010401
Improved beta-thujaplicin production in Cupressus lusitanica suspension cultures by fungal elicitor and methyl jasmonate. Applied microbiology and biotechnology 20010401
Cytotoxicity of the hinokitiol-related compounds, gamma-thujaplicin and beta-dolabrin. Biological & pharmaceutical bulletin 20010301
Does the photochemical conversion of colchicine into lumicolchicines involve triplet transients? A solvent dependence study. Photochemistry and photobiology 20010301
Effects of tolcapone upon soluble and membrane-bound brain and liver catechol-O-methyltransferase. Brain research 19990306
Induction of apoptosis by hinokitiol, a potent iron chelator, in teratocarcinoma F9 cells is mediated through the activation of caspase-3. Cell proliferation 19990201
Thujaplicin-copper chelates inhibit replication of human influenza viruses. Antiviral research 19980801
A new model of ventricular fibrillation induced by isoprenaline and catechol-O-methyl transferase inhibitor at a high perfusion temperature in isolated rat hearts. Journal of pharmacological methods 19851201
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