2-Aminoquinoline
| Title | Journal |
|---|---|
| Lys05: a new lysosomal autophagy inhibitor. | Autophagy 20120901 |
| Aminoquinolines as fluorescent labels for hydrophilic interaction liquid chromatography of oligosaccharides. | Biological chemistry 20120801 |
| One-pot synthesis of 2-aminoquinoline-based alkaloids from acetonitrile. | Organic & biomolecular chemistry 20120714 |
| Synthesis of aminoquinoline-based aminoalcohols and oxazolidinones and their antiplasmodial activity. | Chemical biology & drug design 20120301 |
| Proton grease: an acid accelerated molecular rotor. | Journal of the American Chemical Society 20120227 |
| Reactions of substituted pyridines with electrophilic boranes. | Dalton transactions (Cambridge, England : 2003) 20120221 |
| Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms. | The Journal of biological chemistry 20120203 |
| Antischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoni. | PLoS neglected tropical diseases 20120201 |
| Synthetic peroxides as potent antimalarials. News and views. | Current topics in medicinal chemistry 20120101 |
| Novel binding mode of a potent and selective tankyrase inhibitor. | PloS one 20120101 |
| Antimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasites. | PloS one 20120101 |
| A chelation enhanced selective fluorescence sensing of Hg2+ by a simple quinoline substituted tripodal amide receptor. | Dalton transactions (Cambridge, England : 2003) 20111214 |
| Highly effective therapy for maternal malaria associated with a lower risk of vertical transmission. | The Journal of infectious diseases 20111115 |
| Comprehensive profiling and quantitation of amine group containing metabolites. | Analytical chemistry 20111001 |
| From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1). | Journal of medicinal chemistry 20110825 |
| A residue W756 in the P-loop segment of the sodium channel is critical for primaquine binding. | European journal of pharmacology 20110801 |
| Palladium(II) complexes of quinolinylaminophosphonates: synthesis, structural characterization, antitumor and antimicrobial activity. | Journal of inorganic biochemistry 20110601 |
| {N,N'-[2,2'-(Ethane-1,2-diyldisulfanediyl)di-o-phenyl-ene]bis-(quinoline-2-carboxamidato)}copper(II). | Acta crystallographica. Section E, Structure reports online 20110601 |
| Clinical and Rehabilitative Management of Retinitis Pigmentosa: Up-to-Date. | Current genomics 20110601 |
| Highly sensitive MALDI analyses of glycans by a new aminoquinoline-labeling method using 3-aminoquinoline/α-cyano-4-hydroxycinnamic acid liquid matrix. | Analytical chemistry 20110515 |
| Synthesis, in vitro antimalarial and cytotoxicity of artemisinin-aminoquinoline hybrids. | Bioorganic & medicinal chemistry letters 20110315 |
| Acridine and acridinones: old and new structures with antimalarial activity. | The open medicinal chemistry journal 20110101 |
| Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations. | Malaria journal 20110101 |
| PfMDR1: mechanisms of transport modulation by functional polymorphisms. | PloS one 20110101 |
| Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety. | PloS one 20110101 |
| A girl with cutaneous lesions, polyarthritis, and antinuclear antibodies positivity. | ISRN dermatology 20110101 |
| Molecular-field-based three-dimensional similarity studies on quinoline-based CNS active agents. | ISRN pharmaceutics 20110101 |
| Synthesis and structure of azole-fused indeno[2,1-c]quinolines and their anti-mycobacterial properties. | Organic & biomolecular chemistry 20101221 |
| Reactivity of the bifunctional ambiphilic molecule 8-(dimesitylboryl)quinoline: hydrolysis and coordination to Cu(I), Ag(I) and Pd(II). | Dalton transactions (Cambridge, England : 2003) 20101207 |
| Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds. | Bioorganic & medicinal chemistry 20101201 |
| Synthesis and anti-prion activity evaluation of aminoquinoline analogues. | European journal of medicinal chemistry 20101101 |
| Synthesis and in vitro antiproliferative activity of 5-alkyl-12(H)-quino[3,4-b] [1,4]benzothiazinium salts. | European journal of medicinal chemistry 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| N-[(2-Chloro-8-methyl-quinolin-3-yl)meth-yl]-4-meth-oxy-aniline. | Acta crystallographica. Section E, Structure reports online 20101101 |
| Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobic packing point at the active site of insulin-regulated aminopeptidase. | Molecular pharmacology 20101001 |
| Solution behavior of hematin under acidic conditions and implications for its interactions with chloroquine. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100901 |
| Resonance Raman characterization of the different forms of ground-state 8-substituted 7-hydroxyquinoline caged acetate compounds in aqueous solutions. | The journal of physical chemistry. A 20100225 |
| A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. | Cell death & disease 20100201 |
| Screening a mushroom extract library for activity against Acinetobacter baumannii and Burkholderia cepacia and the identification of a compound with anti-Burkholderia activity. | Annals of clinical microbiology and antimicrobials 20100101 |
| Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. | PloS one 20100101 |
| Establishment of an in vitro assay for assessing the effects of drugs on the liver stages of Plasmodium vivax malaria. | PloS one 20100101 |
| Fluorescent chemosensors for toxic organophosphorus pesticides: a review. | Sensors (Basel, Switzerland) 20100101 |
| Recent developments in the design and synthesis of hybrid molecules based on aminoquinoline ring and their antiplasmodial evaluation. | European journal of medicinal chemistry 20090801 |
| Plasmodium berghei ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model. | Experimental parasitology 20090701 |
| Identification of 2-aminobenzimidazoles as potent melanin-concentrating hormone 1-receptor (MCH1R) antagonists. | Bioorganic & medicinal chemistry letters 20090701 |
| Design, synthesis and biological evaluation of novel triazole, urea and thiourea derivatives of quinoline against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry 20090701 |
| Aminoquinoline derivatives with antiproliferative activity against melanoma cell line. | Bioorganic & medicinal chemistry letters 20090701 |
| Resistance-mediating polymorphisms in Plasmodium falciparum infections in Kinshasa, Democratic Republic of the Congo. | The American journal of tropical medicine and hygiene 20090401 |
| Two complementary fluorimetric assays for the determination of aminoquinoline binding and uptake by human erythrocytes in vitro. | Analytical biochemistry 20090215 |
| Synthesis, characterization, and in vitro antimalarial and antitumor activity of new ruthenium(II) complexes of chloroquine. | Inorganic chemistry 20090202 |
| Malarial parasite pathogenesis and drug targets. | F1000 biology reports 20090101 |
| Sequential and selective Buchwald-Hartwig amination reactions for the controlled functionalization of 6-bromo-2-chloroquinoline: synthesis of ligands for the Tec Src homology 3 domain. | The Journal of organic chemistry 20081121 |
| 4-N-, 4-S-, and 4-O-chloroquine analogues: influence of side chain length and quinolyl nitrogen pKa on activity vs chloroquine resistant malaria. | Journal of medicinal chemistry 20080626 |
| A highly efficient and selective turn-on fluorescent sensor for Cu2+ ion based on calix[4]arene bearing four iminoquinoline subunits on the upper rim. | Chemical communications (Cambridge, England) 20080421 |
| Determination of oseltamivir quality by colorimetric and liquid chromatographic methods. | Emerging infectious diseases 20080401 |
| Development of CXCR3 antagonists. Part 4: discovery of 2-amino-(4-tropinyl)quinolines. | Bioorganic & medicinal chemistry letters 20080115 |
| Hybrid molecules with a dual mode of action: dream or reality? | Accounts of chemical research 20080101 |
| Metallocene antimalarials: the continuing quest. | Metal-based drugs 20080101 |
| The prince and the pauper. A tale of anticancer targeted agents. | Molecular cancer 20080101 |
| Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues. | Bioorganic & medicinal chemistry letters 20071201 |
| Design, synthesis, and preliminary pharmacological evaluation of new quinoline derivatives as nicotinic ligands. | Journal of medicinal chemistry 20071004 |
| Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SK(Ca)). | Bioorganic & medicinal chemistry 20070815 |
| Discovery of cyclopentane- and cyclohexane-trans-1,3-diamines as potent melanin-concentrating hormone receptor 1 antagonists. | Bioorganic & medicinal chemistry letters 20070801 |
| A Cl- anion-responsive luminescent Eu3+ complex with a chiral tripod: ligand substituent effects on ternary complex stoichiometry and anion sensing selectivity. | Dalton transactions (Cambridge, England : 2003) 20070714 |
| Picosecond time-resolved fluorescence study on solute-solvent interaction of 2-aminoquinoline in room-temperature ionic liquids: aromaticity of imidazolium-based ionic liquids. | The journal of physical chemistry. B 20070510 |
| Application of fragment screening by X-ray crystallography to beta-secretase. | Journal of medicinal chemistry 20070322 |
| Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. | Journal of medicinal chemistry 20070322 |
| Quinazoline and benzimidazole MCH-1R antagonists. | Bioorganic & medicinal chemistry letters 20070301 |
| Crystal and molecular structures of trichloro-cobalt(II) complexes of epiquinine, epiquinidine, and epidihydrocinchonine. | Chirality 20070201 |
| Randomized dose-ranging controlled trial of AQ-13, a candidate antimalarial, and chloroquine in healthy volunteers. | PLoS clinical trials 20070101 |
| World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria. | Malaria journal 20070101 |
| Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1-R) antagonists. | Current topics in medicinal chemistry 20070101 |
| Excited-state proton transfer through water bridges and structure of hydrogen-bonded complexes in 1H-pyrrolo[3,2-h]quinoline: adiabatic time-dependent density functional theory study. | The journal of physical chemistry. A 20061102 |
| 2-Aminoquinoline melanin-concentrating hormone (MCH)1R antagonists. | Bioorganic & medicinal chemistry letters 20061015 |
| Application of multicomponent reactions to antimalarial drug discovery. Part 2: New antiplasmodial and antitrypanosomal 4-aminoquinoline gamma- and delta-lactams via a 'catch and release' protocol. | Bioorganic & medicinal chemistry 20060815 |
| Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions. | Journal of the American Chemical Society 20060809 |
| A dynamic tricopper double helicate. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060515 |
| Quinolactacins revisited: from lactams to imide and beyond. | Organic & biomolecular chemistry 20060421 |
| Sensitive fluorescence HPLC assay for AQ-13, a candidate aminoquinoline antimalarial, that also detects chloroquine and N-dealkylated metabolites. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060403 |
| Three 4-aminoquinolines of antimalarial interest. | Acta crystallographica. Section C, Crystal structure communications 20060201 |
| Synthesis of N-benzylated-2-aminoquinolines as ligands for the Tec SH3 domain. | Bioorganic & medicinal chemistry letters 20060115 |
| Molecular surveillance of mutations in the cytochrome b gene of Plasmodium falciparum in Gabon and Ethiopia. | Malaria journal 20060101 |
| The use of genotyping in antimalarial clinical trials: a systematic review of published studies from 1995-2005. | Malaria journal 20060101 |
| Synthesis of C-nucleosides designed to participate in triplex formation with native DNA: specific recognition of an A:T base pair in DNA. | The Journal of organic chemistry 20051028 |
| Structure-function studies on a synthetic guanosine receptor that simultaneously binds Watson-Crick and Hoogsteen sites. | The Journal of organic chemistry 20050916 |
| Synthesis of 5-, 6- and 7-substituted-2-aminoquinolines as SH3 domain ligands. | Organic & biomolecular chemistry 20050721 |
| Steric effect on the nuclease activity of Cu(II) complexes with aminoquinoline derivatives. | Journal of inorganic biochemistry 20050701 |
| Subacute cutaneous lupus erythematosus: 25-year evolution of a prototypic subset (subphenotype) of lupus erythematosus defined by characteristic cutaneous, pathological, immunological, and genetic findings. | Autoimmunity reviews 20050601 |
| Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide synthase. | Bioorganic & medicinal chemistry letters 20050415 |
| [Unwanted reactions to modifying antirheumatic drugs]. | Terapevticheskii arkhiv 20050101 |
| Identification and specificity studies of small-molecule ligands for SH3 protein domains. | Journal of medicinal chemistry 20041021 |
| Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa. | Journal of the American Society for Mass Spectrometry 20040601 |
| Molecular complexes of IQ and 4-hydroxy-coumarin: a mutagen-anti-mutagen system. | Journal of photochemistry and photobiology. B, Biology 20040527 |
| Synthesis and antimalarial activity of trioxaquine derivatives. | Chemistry (Weinheim an der Bergstrasse, Germany) 20040402 |
| 4-Aryl(benzyl)amino-4-heteroarylbut-1-enes as building blocks in heterocyclic synthesis. 4. Synthesis of 4, 6-dimethyl-5-nitro(amino)-2-pyridylquinolines and their antiparasitic activities. | Archiv der Pharmazie 20040301 |
| Antimalarial lichenoid tissue reactions in patients with pre-existing lupus erythematosus. | Lupus 20040101 |
| Genomics research and malaria control: great expectations. | PLoS biology 20031101 |
| Synthesis, characterization and antitumor activity of platinum(II) complexes with diethyl and monoethyl 2-quinolylmethylphosphonates. | Journal of inorganic biochemistry 20030701 |
| Chloroquine and artemisinin: six decades of research--what next? | IDrugs : the investigational drugs journal 20030701 |
| Electrochemical study of hydroxychloroquine and its determination in plaquenil by differential pulse voltammetry. | Journal of pharmaceutical and biomedical analysis 20030601 |
| Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities. | Bioorganic & medicinal chemistry 20030515 |
| Conductometric and indirect AAS determination of antimalarials. | Journal of pharmaceutical and biomedical analysis 20030326 |
| Severe malaria in a splenectomised Gabonese woman. | Wiener klinische Wochenschrift 20030131 |
| Novel zinc fluorescent probe bearing dansyl and aminoquinoline groups. | Chemical communications (Cambridge, England) 20020707 |
| Characterization of a didehydrobenzoxazine intermediate in a novel carbene-to-carbene transformation. | Journal of the American Chemical Society 20020703 |
| Dermatomyositis: an overview of recent progress with emphasis on dermatologic aspects. | Dermatologic clinics 20020701 |
| 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates. | Biochemistry 20020305 |
| Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity. | Journal of medicinal chemistry 20020227 |
| Dissociation and electrooxidation of primaquine diphosphate as an approach to the study of anti-chagas prodrugs mechanism of action. | Bioelectrochemistry (Amsterdam, Netherlands) 20010101 |
| Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13. | Environmental and molecular mutagenesis 20010101 |