sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks EW 7197

EW 7197

CAS No.:
1352608-82-2
Catalog Number:
AG003AC8
Molecular Formula:
C22H18FN7
Molecular Weight:
399.4236
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%(HPLC)
In Stock USA
United States
$212
- +
25mg
98%(HPLC)
In Stock USA
United States
$641
- +
100mg
98%(HPLC)
In Stock USA
United States
$1362
- +
Product Description
Catalog Number:
AG003AC8
Chemical Name:
EW 7197
CAS Number:
1352608-82-2
Molecular Formula:
C22H18FN7
Molecular Weight:
399.4236
MDL Number:
MFCD28348363
IUPAC Name:
2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline
InChI:
InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)
InChI Key:
FJCDSQATIJKQKA-UHFFFAOYSA-N
SMILES:
Cc1cccc(n1)c1[nH]c(nc1c1ccc2n(c1)ncn2)CNc1ccccc1F
UNII:
6T4O391P5Y
Properties
Complexity:
566  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
399.161g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
399.433g/mol
Monoisotopic Mass:
399.161g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
83.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.2  
Literature
Title Journal
Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): a highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent. Journal of medicinal chemistry 20140522
Properties