Ansamitocin p 3'
Title | Journal |
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An isolable acyclic hemiacetal of ansamitocin P-3. | Magnetic resonance in chemistry : MRC 20120301 |
The interplay between mutasynthesis and semisynthesis: generation and evaluation of an ansamitocin library. | Angewandte Chemie (International ed. in English) 20120116 |
Combined muta- and semisynthesis: a powerful synthetic hybrid approach to access target specific antitumor agents based on ansamitocin P3. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120116 |
Dual carbamoylations on the polyketide and glycosyl moiety by asm21 result in extended ansamitocin biosynthesis. | Chemistry & biology 20111223 |
Enhanced production of ansamitocin P-3 by addition of Mg2+ in fermentation of Actinosynnema pretiosum. | Bioresource technology 20111101 |
N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis. | Chembiochem : a European journal of chemical biology 20110725 |
Mutational biosynthesis of ansamitocin antibiotics: a diversity-oriented approach to exploit biosynthetic flexibility. | Chembiochem : a European journal of chemical biology 20110307 |
Enhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosum. | Bioresource technology 20110101 |
Cyclization of synthetic seco-proansamitocins to ansamitocin macrolactams by Actinosynnema pretiosum as biocatalyst. | Chembiochem : a European journal of chemical biology 20101210 |
A new antitumour ansamitocin from Actinosynnema pretiosum. | Natural product research 20100701 |
Preparative isolation and purification of anti-tumor agent ansamitocin P-3 from fermentation broth of Actinosynnema pretiosum using high-performance counter-current chromatography. | Journal of separation science 20100501 |
Constitutive overexpression of asm2 and asm39 increases AP-3 production in the actinomycete Actinosynnema pretiosum. | Journal of industrial microbiology & biotechnology 20091101 |
Timing of the Delta(10,12)-Delta(11,13) double bond migration during ansamitocin biosynthesis in Actinosynnema pretiosum. | Journal of the American Chemical Society 20090325 |
Amide N-glycosylation by Asm25, an N-glycosyltransferase of ansamitocins. | Chemistry & biology 20080825 |
Highly active ansamitocin derivatives: mutasynthesis using an AHBA-blocked mutant. | Chembiochem : a European journal of chemical biology 20080505 |
The ansacarbamitocins: polar ansamitocin derivatives. | Journal of natural products 20071001 |
New amide N-glycosides of ansamitocins identified from Actinosynnema pretiosum. | Archives of pharmacal research 20070601 |
An integrative expression vector for Actinosynnema pretiosum. | BMC biotechnology 20070101 |
On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of 'glycolate' units into ansamitocin and soraphen A. | Journal of the American Chemical Society 20061108 |
Determination of the cryptic stereochemistry of the first PKS chain-extension step in ansamitocin biosynthesis by Actinosynnema pretiosum. | Chembiochem : a European journal of chemical biology 20060801 |
Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. | Journal of mass spectrometry : JMS 20050301 |
An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics. | Journal of pharmaceutical and biomedical analysis 20041119 |
A novel amide N-glycoside of ansamitocins from Actinosynnema pretiosum. | The Journal of antibiotics 20040501 |
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum. | Journal of the American Chemical Society 20031126 |
Identification of asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate. | Journal of the American Chemical Society 20020612 |
Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual 'glycolate' chain extension unit in ansamitocin biosynthesis. | Journal of the American Chemical Society 20020424 |