Home Carbonyls 2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol hydrochloride

2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol hydrochloride

CAS No.:
82640-04-8
Catalog Number:
AG003AAG
Molecular Formula:
C28H28ClNO4S
Molecular Weight:
510.0442
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$32
- +
5g
97%
In Stock USA
United States
$100
- +
10g
97%
In Stock USA
United States
$175
- +
25g
97%
In Stock USA
United States
$350
- +
Product Description
Catalog Number:
AG003AAG
Chemical Name:
2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol hydrochloride
CAS Number:
82640-04-8
Molecular Formula:
C28H28ClNO4S
Molecular Weight:
510.0442
MDL Number:
MFCD01938233
IUPAC Name:
[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;hydrochloride
InChI:
InChI=1S/C28H27NO4S.ClH/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29;/h4-13,18,30-31H,1-3,14-17H2;1H
InChI Key:
BKXVVCILCIUCLG-UHFFFAOYSA-N
SMILES:
Oc1ccc2c(c1)sc(c2C(=O)c1ccc(cc1)OCCN1CCCCC1)c1ccc(cc1)O.Cl
UNII:
4F86W47BR6
Properties
Complexity:
655  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
509.143g/mol
Formal Charge:
0
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
510.045g/mol
Monoisotopic Mass:
509.143g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
98.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
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Adherence and persistence in patients with postmenopausal osteoporosis treated with raloxifene. Climacteric : the journal of the International Menopause Society 20110401
Estrogen receptor ligands counteract cognitive deficits caused by androgen deprivation in male rats. Hormones and behavior 20110401
Design, synthesis, and biological evaluation of imidazolyl derivatives of 4,7-disubstituted coumarins as aromatase inhibitors selective over 17-α-hydroxylase/C17-20 lyase. Journal of medicinal chemistry 20110324
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Migraine in women with chronic pelvic pain with and without endometriosis. Fertility and sterility 20110301
Risk of femoral shaft and subtrochanteric fractures among users of bisphosphonates and raloxifene. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110301
Treatment of osteoporosis and reduction in risk of invasive breast cancer in postmenopausal women with raloxifene. Expert opinion on pharmacotherapy 20110301
Do selective estrogen receptor modulators treat cervical precancer and cancer? Time to pool data from relevant trials. International journal of cancer 20110215
Tamoxifen and raloxifene suppress the proliferation of estrogen receptor-negative cells through inhibition of glutamine uptake. Cancer chemotherapy and pharmacology 20110201
The effects of native and synthetic estrogenic compounds as well as vitamin D less-calcemic analogs on adipocytes content in rat bone marrow. Journal of endocrinological investigation 20110201
Effects of the combination treatment of raloxifene and alendronate on the biomechanical properties of vertebral bone. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110201
The inhibitory effect of raloxifene on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells is mediated through a ROS/p38 MAPK/CREB pathway to the up-regulation of heme oxygenase-1 independent of estrogen receptor. Biochimie 20110201
The effects of raloxifene on bone turnover markers and bone mineral density in women on maintenance hemodialysis. Clinical and experimental nephrology 20110201
Selective estrogen receptor modulators as brain therapeutic agents. Journal of molecular endocrinology 20110201
Computational estimation of rainbow trout estrogen receptor binding affinities for environmental estrogens. Toxicology and applied pharmacology 20110201
Effect of raloxifene on arthritis and bone mineral density in rats with collagen-induced arthritis. Calcified tissue international 20110201
Evaluation of estrogen and progesterone receptors in non-neoplastic breast tissue of women of reproductive age exposed to tamoxifen and raloxifene: a randomized, double-blind study. Breast cancer research and treatment 20110201
Persistent and non-persistent changes in gene expression result from long-term estrogen exposure of MCF-7 breast cancer cells. The Journal of steroid biochemistry and molecular biology 20110201
The effects of estrogen receptors α- and β-specific agonists and antagonists on cell proliferation and energy metabolism in human bone cell line. Journal of cellular biochemistry 20110201
In-vitro antiproliferative activity of benzopyranone derivatives in comparison with standard chemotherapeutic drugs. Archiv der Pharmazie 20110201
Reduction of stimulated sodium iodide symporter expression by estrogen receptor ligands in breast cancer cells. Nuclear medicine and biology 20110201
Effects of raloxifene on the production of cytokines in stimulated whole blood in ex vivo and in vitro studies. The journal of medical investigation : JMI 20110201
Alendronate and raloxifene affect the osteoprotegerin/RANKL system in human osteoblast primary cultures from patients with osteoporosis and osteoarthritis. European journal of pharmacology 20110115
Randomized, controlled study of the effects of raloxifene on high sensitivity C-reactive protein and serum lipids. Archives of gynecology and obstetrics 20110101
Raloxifene, a selective estrogen receptor modulator, is renoprotective: a post-hoc analysis. Kidney international 20110101
The gynecologic effects of lasofoxifene, an estrogen agonist/antagonist, in postmenopausal women. Menopause (New York, N.Y.) 20110101
Effects of raloxifene on voltage-dependent T-type Ca2+ channels in mouse spermatogenic cells. Pharmacology 20110101
Prevention of breast cancer: the case for studying inhibition of IGF-1 actions. Annals of oncology : official journal of the European Society for Medical Oncology 20110101
Fibroids (uterine myomatosis, leiomyomas). BMJ clinical evidence 20110101
Cellular mechanisms of acute decrease of glutamate release induced by raloxifene in rat cerebral cortex. Neuropharmacology 20110101
Fracture prevention in postmenopausal women. BMJ clinical evidence 20110101
Estrogens and selective estrogen receptor modulators regulate gene and protein expression in the mesenteric arteries. Vascular pharmacology 20110101
Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis. Arthritis research & therapy 20110101
[Better informed decisions in the management of osteoporosis]. Reumatologia clinica 20110101
Exemestane is effective for the chemoprevention of breast cancer. CA: a cancer journal for clinicians 20110101
Effect of Cissus quadrangularis Linn on the development of osteopenia induced by ovariectomy in rats. La Clinica terapeutica 20110101
Effect of raloxifene (a Selective Estrogen Receptor Modulator (SERM)) as coadjuvant to antidepressant treatment: a case report. Actas espanolas de psiquiatria 20110101
Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells. PloS one 20110101
Four decades of discovery in breast cancer research and treatment--an interview with V. Craig Jordan. Interview by Marc Poirot. The International journal of developmental biology 20110101
The effect of long-term hormonal treatment on voiding patterns during filling cystometry and on urethral histology in a postpartum, ovariectomized female rat. BJU international 20101201
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My doctor wanted me to start taking Evista (raloxifene hydrochloride) for osteoporosis, but I'm worried because the drug is linked to a risk of blood clots. I have mild hypertension that I manage with medications, diet and exercise. Do you think the drug is safe? Heart advisor 20100501
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The effects of long-term raloxifene and estradiol treatments on bone in a patient with congenital aromatase deficiency. Bone 20091101
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Tamoxifen inhibits inward rectifier K+ 2.x family of inward rectifier channels by interfering with phosphatidylinositol 4,5-bisphosphate-channel interactions. The Journal of pharmacology and experimental therapeutics 20091101
Budget impact analysis of chemoprevention of breast cancer with tamoxifen and raloxifene among high-risk women in Japan. Japanese journal of clinical oncology 20091101
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Effects of raloxifene on Ki-67 and CD34 antigen expression in breast cancer. Gynecologic and obstetric investigation 20090101
Potential use of an estrogen-glucocorticoid receptor chimera as a drug screen for tissue selective estrogenic activity. Bone 20090101
Raloxifene use in clinical practice: efficacy and safety. Menopause (New York, N.Y.) 20090101
The NSABP Study of Tamoxifen and Raloxifene (STAR) trial. Expert review of anticancer therapy 20090101
The levels of glutathione and nitrite-nitrate and the expression of Bcl-2 mRNA in ovariectomized rats treated by raloxifene against kainic acid. The International journal of neuroscience 20090101
Estrogen receptor-beta as a potential target for colon cancer prevention: chemoprevention of azoxymethane-induced colon carcinogenesis by raloxifene in F344 rats. Cancer prevention research (Philadelphia, Pa.) 20090101
Two years adherence to anti-osteoporotic medications in postmenopausal Israeli women. Archives of gerontology and geriatrics 20090101
The use of tamoxifen and raloxifene for the prevention of breast cancer. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20090101
Targeted delivery of insulin-modified immunoliposomes in vivo. Journal of liposome research 20090101
Low-dose transdermal estradiol induces breast density and heterogeneity changes comparable to those of raloxifene. Menopause (New York, N.Y.) 20090101
Raloxifene and stroke risks in Japanese postmenopausal women with osteoporosis on postmarketing surveillance. Menopause (New York, N.Y.) 20090101
A comparative study of the effects of genistein, estradiol and raloxifene on the murine skeletal system. Acta biochimica Polonica 20090101
Effect of microdose transdermal 17beta-estradiol compared with raloxifene in the prevention of bone loss in healthy postmenopausal women: a 2-year, randomized, double-blind trial. Menopause (New York, N.Y.) 20090101
The role of pH in the glucuronidation of raloxifene, mycophenolic acid and ezetimibe. Molecular pharmaceutics 20090101
The effects of bazedoxifene on mammographic breast density in postmenopausal women with osteoporosis. Menopause (New York, N.Y.) 20090101
Effect of low-dose tacrolimus coadministered with raloxifene on the skeletal system in male rats. Acta poloniae pharmaceutica 20090101
Mean residence time as estimated from cropped and truncated moments. Arzneimittel-Forschung 20090101
Altering the propensity for density: the benefits and risks of selective estrogen receptor modulators. Menopause (New York, N.Y.) 20090101
Clinical issues regarding cardiovascular disease and selective estrogen receptor modulators in postmenopausal women. Climacteric : the journal of the International Menopause Society 20090101
Estrogenic control of mitochondrial function and biogenesis. Journal of cellular biochemistry 20081215
Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition. Archives of toxicology 20081201
Parathyroid hormone treatment for osteoporosis. Current opinion in endocrinology, diabetes, and obesity 20081201
Five female cases of prolonged depression in chronic anorexia nervosa treated with selective estrogen receptor modulator raloxifene-augmented therapy. Journal of clinical psychopharmacology 20081201
Chemoprevention of breast cancer. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081201
Managing the risk of invasive breast cancer in women at risk for breast cancer and osteoporosis: the role of raloxifene. Clinical interventions in aging 20081201
Effect of intestinal glucuronidation in limiting hepatic exposure and bioactivation of raloxifene in humans and rats. Chemical research in toxicology 20081201
Selective estrogen receptor modulation influences atherosclerotic plaque composition in a rabbit menopause model. Atherosclerosis 20081101
Effects of genistein aglycone in osteoporotic, ovariectomized rats: a comparison with alendronate, raloxifene and oestradiol. British journal of pharmacology 20081101
Estrogen directly modulates circadian rhythms of PER2 expression in the uterus. American journal of physiology. Endocrinology and metabolism 20081101
Effects of estrogen, raloxifene and levormeloxifene on alpha1A-adrenergic receptor expression. The Journal of urology 20081101
Development of an early biomarker for the ovarian liability of selective estrogen receptor modulators in rats. The Journal of steroid biochemistry and molecular biology 20081101
Raloxifene effects on thyroid gland morphology in ovariectomized rats. Fertility and sterility 20081001
Raloxifene protects endothelial cell function against oxidative stress. British journal of pharmacology 20081001
Are the serum levels of sCD40L modified by raloxifene in postmenopausal women? European journal of obstetrics, gynecology, and reproductive biology 20081001
Comparative effects of estradiol, methyl-piperidino-pyrazole, raloxifene, and ICI 182 780 on gene expression in the murine uterus. Journal of molecular endocrinology 20081001
Conjugated equine estrogen, raloxifene and arterial stiffness in postmenopausal women. Climacteric : the journal of the International Menopause Society 20081001
Regulation of estrogenic effects by beclin 1 in breast cancer cells. Cancer research 20081001
[Evidence for the selective estrogen receptor modulator raloxifene: its evolving role in the treatment of osteoporosis]. Clinical calcium 20081001
[Treatment of osteoporosis in the elderly: what is the evidence?]. Tijdschrift voor gerontologie en geriatrie 20081001
Effects of tamoxifen and raloxifene on normal human endometrial cells in an organotypic in vitro model. European journal of pharmacology 20080911
Pharmacokinetics and tolerability of exemestane in combination with raloxifene in postmenopausal women with a history of breast cancer. Breast cancer research and treatment 20080901
Estrogen regulates responses of dopamine neurons in the ventral tegmental area to cocaine. Psychopharmacology 20080901
Association of ovarian and uterine cancers with postmenopausal hormonal treatments. Clinical obstetrics and gynecology 20080901
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose. Chemical research in toxicology 20080901
Treatment of osteoporosis: all the questions we still cannot answer. The American journal of medicine 20080901
Impact of raloxifene or tamoxifen use on endometrial cancer risk: a population-based case-control study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080901
Toward optimal health: advances in breast cancer detection and management. Interview by Jodi R. Godfrey. Journal of women's health (2002) 20080901
Dosing time-dependent effect of raloxifene on plasma fibrinogen concentration in ovariectomized rats. Chronobiology international 20080901
Raloxifene, a selective estrogen receptor modulator, induces mitochondria-mediated apoptosis in human endometrial carcinoma cells. Medical molecular morphology 20080901
To switch or not to switch: should the study of tamoxifen and raloxifene (STAR) trial alter our decision? Taiwanese journal of obstetrics & gynecology 20080901
[Treatment of osteoporosis in octogenarians]. Revue medicale de Bruxelles 20080901
Gradient HPLC analysis of raloxifene hydrochloride and its application to drug quality control. Acta pharmaceutica (Zagreb, Croatia) 20080901
Effects of tibolone and raloxifene on bone mineral density in osteopenic postmenopausal women. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080801
Osteoporosis treatment and fracture incidence: the ICARO longitudinal study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080801
Effect of raloxifene on the vaginal epithelium of postmenopausal women. European journal of obstetrics, gynecology, and reproductive biology 20080801
[Daily practice using the guidelines for prevention and treatment of osteoporosis. Utilization of metabolic markers of bone in daily osteoporosis practice]. Clinical calcium 20080801
The endocrine prevention of breast cancer. Best practice & research. Clinical endocrinology & metabolism 20080801
Raloxifene, a selective estrogen receptor modulator, inhibits lipopolysaccharide-induced nitric oxide production by inhibiting the phosphatidylinositol 3-kinase/Akt/nuclear factor-kappa B pathway in RAW264.7 macrophage cells. Molecules and cells 20080731
Raloxifene analogue LY117018 suppresses oxidative stress-induced endothelial cell apoptosis through activation of ERK1/2 signaling pathway. European journal of pharmacology 20080728
Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells. Molecular and cellular endocrinology 20080716
Effects of teriparatide on serum calcium in postmenopausal women with osteoporosis previously treated with raloxifene or alendronate. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080701
Trends in HRT and anti-osteoporosis medication prescribing in a European population after the WHI study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080701
The effect of raloxifene treatment in postmenopausal women with CKD. Journal of the American Society of Nephrology : JASN 20080701
Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs. The Journal of endocrinology 20080701
Efficacy of Raloxifen in treatment of fibromyalgia in menopausal women. European journal of internal medicine 20080701
Effect of raloxifene on mammographic density and breast magnetic resonance imaging in premenopausal women at increased risk for breast cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080701
[Role of estrogen and selective estrogen receptor modulators in anti-aging]. Clinical calcium 20080701
Understanding risk factors, screening, and treatment of postmenopausal osteoporosis. Orthopedics 20080701
Impact of economic, regulatory, and patent policies on innovation in cancer chemoprevention. Cancer prevention research (Philadelphia, Pa.) 20080701
Rationale for using raloxifene to prevent both osteoporosis and breast cancer in postmenopausal women. Maturitas 20080620
The rise of raloxifene and the fall of invasive breast cancer. Journal of the National Cancer Institute 20080618
Reduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk. Journal of the National Cancer Institute 20080618
Activity of three selective estrogen receptor modulators on hormone-dependent responses in the mouse uterus and mammary gland. Molecular and cellular endocrinology 20080611
pH control of nucleophilic/electrophilic oxidation. International journal of pharmaceutics 20080605
Review of comparative effectiveness of treatments to prevent fractures. Annals of internal medicine 20080603
Using location, color, size, and depth to characterize and identify endometriosis lesions in a cohort of 133 women. Fertility and sterility 20080601
Comparative effects of 17beta-estradiol, raloxifene and genistein on bone 3D microarchitecture and volumetric bone mineral density in the ovariectomized mice. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080601
Adherence to bisphosphonates therapy and hip fracture risk in osteoporotic women. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080601
Effects of raloxifene and hormone replacement therapy on serum Th2 and Th3 type cytokine concentrations in healthy postmenopausal women: a randomised controlled trial. Archives of gynecology and obstetrics 20080601
Raloxifene can reduce giant cell tumor recurrence: a new adjuvant therapy. Annals of surgical oncology 20080601
Differential impact of conventional-dose and low-dose postmenopausal hormone therapy, tibolone and raloxifene on C-reactive protein and other inflammatory markers. Journal of thrombosis and haemostasis : JTH 20080601
Long-term anti-arthritic and anti-osteoporotic effects of raloxifene in established experimental postmenopausal polyarthritis. Clinical and experimental immunology 20080601
Genomic deletion of estrogen receptors ERalpha and ERbeta does not alter estrogen-mediated inhibition of Ca2+ influx and contraction in murine cardiomyocytes. American journal of physiology. Heart and circulatory physiology 20080601
[Muscle and bone health as a risk factor of fall among the elderly. Role of raloxifene in the prevention of osteoporotic fractures]. Clinical calcium 20080601
Effects of estrogen and estrogenic compounds on cognition in ovariectomized rats. Climacteric : the journal of the International Menopause Society 20080601
Clinical challenges in the management of osteoporosis. Clinical interventions in aging 20080601
Differential effects of ovarian steroids and raloxifene on serotonin 1A and 2C receptor protein expression in macaques. Endocrine 20080601
Summaries for patients. Drug therapy for osteoporosis. Annals of internal medicine 20080506
Relative effectiveness of osteoporosis drugs for preventing nonvertebral fracture. Annals of internal medicine 20080506
The search for good compliance: economic aspects of a conveyed combination pharmaco-therapy, exemplified by an osteoporosis therapy. The European journal of health economics : HEPAC : health economics in prevention and care 20080501
Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells. Breast cancer research and treatment 20080501
Increased antitumor potential of the raloxifene prodrug, raloxifene diphosphate. International journal of cancer 20080501
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers. International journal of cancer 20080501
Differential impact of conventional and low-dose oral hormone therapy, tibolone and raloxifene on mammographic breast density, assessed by an automated quantitative method. BJOG : an international journal of obstetrics and gynaecology 20080501
Raloxifene in breast cancer prevention. Expert opinion on drug safety 20080501
Raloxifene has favourable effects on metabolic parameters but has no effect on left ventricular function in postmenopausal women. Pharmacological research 20080501
Gene expression profiles in breast cancer to identify estrogen receptor target genes. Mini reviews in medicinal chemistry 20080501
The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance. Frontiers in bioscience : a journal and virtual library 20080501
Effects of raloxifene therapy on circulating osteoprotegerin and RANK ligand levels in post-menopausal osteoporosis. Journal of endocrinological investigation 20080501
Preventing breast cancer in high-risk women, 2008. Oncology (Williston Park, N.Y.) 20080501
Difference between genomic actions of estrogen versus raloxifene in human ovarian cancer cell lines. Oncogene 20080424
The combination of raloxifene and epigallocatechin gallate suppresses growth and induces apoptosis in MDA-MB-231 cells. Life sciences 20080423
Daidzein but not other phytoestrogens preserves bone architecture in ovariectomized female rats in vivo. Journal of cellular biochemistry 20080415
Interest in breast cancer chemoprevention among older women. Breast cancer research and treatment 20080401
E-cadherin expression in cervical epithelial cells of postmenopausal women: association with hormone therapy, tibolone, and raloxifene. Fertility and sterility 20080401
An evidence-based approach to hormonal therapies for premenopausal women with fibroids. Best practice & research. Clinical obstetrics & gynaecology 20080401
Effect of prior and ongoing raloxifene therapy on response to PTH and maintenance of BMD after PTH therapy. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080401
Effects of bazedoxifene on BMD and bone turnover in postmenopausal women: 2-yr results of a randomized, double-blind, placebo-, and active-controlled study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080401
Circulating levels of atherogenesis-associated adipocytokines and apoptotic markers are differentially influenced by hormone therapy, tibolone and raloxifene in healthy postmenopausal women. Climacteric : the journal of the International Menopause Society 20080401
[Expression of Bax protein in normal tissue of premenopausal women treated with raloxifene]. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 20080401
Effects of raloxifene on insulin sensitivity, beta-cell function, and hepatic insulin extraction in normal postmenopausal women. Fertility and sterility 20080301
Bone turnover and bone collagen maturation in osteoporosis: effects of antiresorptive therapies. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080301
Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagle dog vertebra. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080301
Association between baseline values of bone turnover markers and bone mineral density and their response to raloxifene treatment in Japanese postmenopausal women with osteoporosis. Endocrine journal 20080301
Efficacy of combined treatment with raloxifene and alfacalcidol on bone density and biochemical markers of bone turnover in postmenopausal osteoporosis. Endocrine journal 20080301
Relationship between bone mass, invasive breast cancer incidence and raloxifene therapy in postmenopausal women with low bone mass or osteoporosis. Current medical research and opinion 20080301
[Assessment of bone quality. Bone quality and osteoporosis treatment]. Clinical calcium 20080301
[Assessment of bone quality. Effects of bisphosphonates, raloxifene, alfacalcidol, and menatetrenone on bone quality: collagen cross-links, mineralization, and microdamage]. Clinical calcium 20080301
Chemoprevention of breast cancer. Expert review of anticancer therapy 20080301
The role of selective estrogen receptor modulators on breast cancer: from tamoxifen to raloxifene. Taiwanese journal of obstetrics & gynecology 20080301
Tamoxifen: to use or not to use. Taiwanese journal of obstetrics & gynecology 20080301
Raloxifene for older women: a review of the literature. Clinical interventions in aging 20080301
[Raloxifene in clinical practice. Results of the non-interventional study CORAL (COmpliance with RALoxifene)]. Vnitrni lekarstvi 20080301
Comparison of effects of alendronate and raloxifene on lumbar bone mineral density, bone turnover, and lipid metabolism in elderly women with osteoporosis. Yonsei medical journal 20080227
Differential regulation of native estrogen receptor-regulatory elements by estradiol, tamoxifen, and raloxifene. Molecular endocrinology (Baltimore, Md.) 20080201
Selective estrogen receptor modulators accelerate cutaneous wound healing in ovariectomized female mice. Endocrinology 20080201
The potential influence of CO2, as an agent for euthanasia, on the pharmacokinetics of basic compounds in rodents. Drug metabolism and disposition: the biological fate of chemicals 20080201
Role of raloxifene on platelet metabolism and plasma lipids. European journal of clinical investigation 20080201
Effect of raloxifene therapy on venous thromboembolism in postmenopausal women. A meta-analysis. Thrombosis and haemostasis 20080201
[The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment]. Zhonghua yi xue za zhi 20080122
[Long term effects of raloxifen on the bones]. Ugeskrift for laeger 20080121
Circulating leptin and ghrelin are differentially influenced by estrogen/progestin therapy and raloxifene. Maturitas 20080120
Pharmacokinetics of raloxifene in male Wistar-Hannover rats: influence of complexation with hydroxybutenyl-beta-cyclodextrin. International journal of pharmaceutics 20080104
The effects of raloxifen on depression and cognition in ovariectomized rats. Fertility and sterility 20080101
Effects of estradiol and raloxifene on arterial thrombosis in ovariectomized mice. Menopause (New York, N.Y.) 20080101
Hereditary breast cancer: pathobiology, clinical translation, and potential for targeted cancer therapeutics. Familial cancer 20080101
Pharmacophore mapping of arylbenzothiophene derivatives for MCF cell inhibition using classical and 3D space modeling approaches. Journal of molecular graphics & modelling 20080101
Effects of raloxifene on fracture risk in postmenopausal women: the Raloxifene Use for the Heart Trial. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20080101
Effect of raloxifene after recombinant teriparatide [hPTH(1-34)] treatment in postmenopausal women with osteoporosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080101
Hormone modulation: a novel therapeutic approach for women with severe mental illness. The Australian and New Zealand journal of psychiatry 20080101
Tamoxifen: catalyst for the change to targeted therapy. European journal of cancer (Oxford, England : 1990) 20080101
Return of chronic pelvic pain from endometriosis after raloxifene treatment: a randomized controlled trial. Obstetrics and gynecology 20080101
Chemoprevention of breast cancer. Breast cancer (Tokyo, Japan) 20080101
Three-month changes in bone turnover markers and bone mineral density response to raloxifene in Japanese postmenopausal women with osteoporosis. Journal of bone and mineral metabolism 20080101
Randomized clinical trials of raloxifene: reducing the risk of osteoporosis and breast cancer in postmenopausal women. Menopause (New York, N.Y.) 20080101
Risks, benefits, and effects on quality of life of selective estrogen-receptor modulator therapy in postmenopausal women at increased risk of breast cancer. Menopause (New York, N.Y.) 20080101
Prevention of breast cancer using SERMs. Advances in experimental medicine and biology 20080101
[Effect of the raloxifene versus combined hormonal therapy on the mammary density]. Revista medica del Instituto Mexicano del Seguro Social 20080101
[Hormone replacement therapy and cardiovascular prevention. Where are we now?]. Medicina 20080101
Raloxifene-induced acceleration of platelet aggregation. Internal medicine (Tokyo, Japan) 20080101
Raloxifene: a review of its use in the prevention of invasive breast cancer. Drugs 20080101
Raloxifene plus ossein-hydroxyapatite compound versus raloxifene plus calcium carbonate to control bone loss in postmenopausal women: a randomized trial. Menopause (New York, N.Y.) 20080101
A comparison of hormone therapies on the urinary excretion of prostacyclin and thromboxane A2. Climacteric : the journal of the International Menopause Society 20080101
Effects of raloxifene on the urethra of adult castrated female rats. Climacteric : the journal of the International Menopause Society 20080101
Characteristics of patients initiating raloxifene compared to those initiating bisphosphonates. BMC women's health 20080101
Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071220
Projecting individualized absolute invasive breast cancer risk in African American women. Journal of the National Cancer Institute 20071205
Gynecologic and hormonal effects of raloxifene in premenopausal women. Fertility and sterility 20071201
Mechanism of the divergent effects of estrogen on the cell proliferation of human umbilical endothelial versus aortic smooth muscle cells. Endocrinology 20071201
Clinical significance of 1-year treatment with raloxifene on bone and lipid metabolism in Japanese postmenopausal women with osteoporosis. Endocrine journal 20071201
Differential time-dependent inactivation of P450 3A4 and P450 3A5 by raloxifene: a key role for C239 in quenching reactive intermediates. Chemical research in toxicology 20071201
Raloxifene, soy phytoestrogens and endothelial function in postmenopausal women. Climacteric : the journal of the International Menopause Society 20071201
Effect of raloxifene on cerebral vasospasm following experimental subarachnoid hemorrhage in rats. Neurologia medico-chirurgica 20071201
The effects of raloxifene and tibolone on homocysteine and vascular histopathological changes. Clinical and experimental medicine 20071201
Breast cancer risk management. Clinical breast cancer 20071201
[Where do SERMs stand in the light of clinical application?]. Nihon rinsho. Japanese journal of clinical medicine 20071128
[First choice drug for treatment of osteoporosis and the strategic points for choice of drugs]. Nihon rinsho. Japanese journal of clinical medicine 20071128
[CORE study]. Nihon rinsho. Japanese journal of clinical medicine 20071128
[Combination therapy for osteoporosis]. Nihon rinsho. Japanese journal of clinical medicine 20071128
[Evidence of raloxifene on postmenopausal osteoporosis]. Nihon rinsho. Japanese journal of clinical medicine 20071128
[Effects of SERM on the cardiovascular system]. Nihon rinsho. Japanese journal of clinical medicine 20071128
[Transplantation and osteoporosis]. Nihon rinsho. Japanese journal of clinical medicine 20071128
[Osteoporosis in cancer survivors]. Medicina clinica 20071110
A comparative study of the effect of raloxifene and gosereline on uterine leiomyoma volume changes and estrogen receptor, progesterone receptor, bcl-2 and p53 expression immunohistochemically in premenopausal women. European journal of obstetrics, gynecology, and reproductive biology 20071101
Uterine peroxidase-catalyzed formation of diquinone methides from the selective estrogen receptor modulators raloxifene and desmethylated arzoxifene. Chemical research in toxicology 20071101
Patient compliance with alendronate, risedronate and raloxifene for the treatment of osteoporosis in postmenopausal women. Current medical research and opinion 20071101
Cognitive effects of short-term use of raloxifene: a randomized clinical trial. The International journal of neuroscience 20071101
Tamoxifen or raloxifene for breast cancer chemoprevention: a tale of two choices--point. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20071101
Tamoxifen or raloxifene in postmenopausal women for prevention of breast cancer: a tale of two choices--counterpoint. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20071101
[Adverse events of drugs for the treatment of osteoporosis]. Nihon rinsho. Japanese journal of clinical medicine 20071028
Effects of tibolone and raloxifene on health-related quality of life and sexual function. Maturitas 20071020
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas. The Cochrane database of systematic reviews 20071017
Structure-activity relationships for a family of benzothiophene selective estrogen receptor modulators including raloxifene and arzoxifene. ChemMedChem 20071001
Identification of cytochrome P450 3A4 modification site with reactive metabolite using linear ion trap-Fourier transform mass spectrometry. Chemical research in toxicology 20071001
Effects of hormone treatment on hemostasis variables. Climacteric : the journal of the International Menopause Society 20071001
Osteoporosis: non-hormonal treatment. Climacteric : the journal of the International Menopause Society 20071001
Protective effect of raloxifene on lipopolysaccharide and acid- induced acute lung injury in rats. Acta pharmacologica Sinica 20071001
Role of raloxifene as a potent inhibitor of experimental postmenopausal polyarthritis and osteoporosis. Arthritis and rheumatism 20071001
Modern milk alkali syndrome--a preventable serious condition. The New Zealand medical journal 20070921
Follow-up of patients with early breast cancer. The New England journal of medicine 20070906
SERMs for the treatment and prevention of breast cancer. Reviews in endocrine & metabolic disorders 20070901
Therapeutic concentrations of raloxifene augment nitric oxide-dependent coronary artery dilatation in vitro. British journal of pharmacology 20070901
Effect of raloxifene treatment on osteocyte apoptosis in postmenopausal women. Calcified tissue international 20070901
Rapid endometrial preparation for hysteroscopic surgery with oral desogestrel plus vaginal raloxifene: a prospective, randomized pilot study. Fertility and sterility 20070901
Raloxifene examined for breast cancer prevention. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070901
[Hormone replacement Up-to-date. Selective estrogen receptor modulator (SERM) for the treatment of osteoporosis]. Clinical calcium 20070901
Influence of the selective oestrogen receptor modulator (raloxifene hydrochloride) on IL-6, TNF-alpha, TGF-beta1 and bone turnover markers in the treatment of postmenopausal osteoporosis. European cytokine network 20070901
Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms. Molecular cancer therapeutics 20070901
[Current and future prospects for anti-osteoporotic drugs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070901
The STAR trial: evidence for raloxifene as a breast cancer risk reduction agent for postmenopausal women. Journal of the National Comprehensive Cancer Network : JNCCN 20070901
Resonance Rayleigh scattering spectral method for the determination of raloxifene using gold nanoparticle as a probe. Analytica chimica acta 20070829
Hope for axed cancer-prevention trial. Nature 20070823
Development and validation of a liquid chromatography-tandem mass spectrometry assay for determination of raloxifene and its metabolites in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070815
The effect of raloxifene in association with vitamin D on vaginal maturation index and urogenital symptoms in postmenopausal osteoporotic women. Fertility and sterility 20070801
Raloxifene increases proliferation of human endothelial cells in association with increased gene expression of cyclins A and B1. Fertility and sterility 20070801
Effect of raloxifene -- a selective oestrogen receptor modulator -- on kidney function in post-menopausal women with Type 2 diabetes: results from a randomized, placebo-controlled pilot trial. Diabetic medicine : a journal of the British Diabetic Association 20070801
QUS in monitoring raloxifene and estrogen-progestogens: a 4-year longitudinal study. Ultrasound in medicine & biology 20070801
Raloxifene enhances material-level mechanical properties of femoral cortical and trabecular bone. Endocrinology 20070801
Raloxifene inhibits matrix metalloproteinases expression and activity in macrophages and smooth muscle cells. Pharmacological research 20070801
Raloxifene, tamoxifen and vascular tone. Clinical and experimental pharmacology & physiology 20070801
Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy. Nature clinical practice. Endocrinology & metabolism 20070801
Raloxifene: cardiovascular considerations. Mini reviews in medicinal chemistry 20070801
[Review of pharmacological treatment of the menopause]. Atencion primaria 20070801
Effects of hormonal therapy on cognitive functioning in breast cancer patients: a review of the literature. Minerva ginecologica 20070801
Circulating chemoattractants RANTES, negatively related to endogenous androgens, and MCP-1 are differentially suppressed by hormone therapy and raloxifene. Atherosclerosis 20070701
Multiple transcription factor elements collaborate with estrogen receptor alpha to activate an inducible estrogen response element in the NKG2E gene. Endocrinology 20070701
Hormone therapy and raloxifene reduce the coagulation inhibitor potential. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070701
Comparison of the effects of raloxifene and low-dose hormone replacement therapy on bone mineral density and bone turnover in the treatment of postmenopausal osteoporosis. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20070701
NCI and the STELLAR trial. Lancet (London, England) 20070630
Raloxifene acutely reduces glutamate-induced intracellular calcium increase in cultured rat cortical neurons via inhibition of high-voltage-activated calcium current. Neuroscience 20070629
[Prevention of hereditary breast cancer]. Nihon rinsho. Japanese journal of clinical medicine 20070628
[Current perspective of chemoprevention in breast cancer]. Nihon rinsho. Japanese journal of clinical medicine 20070628
Moving forward with breast cancer prevention. Cancer 20070615
Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells. Oncogene 20070614
Raloxifene inhibits transient outward and ultra-rapid delayed rectifier potassium currents in human atrial myocytes. European journal of pharmacology 20070601
Hormonal interventions to prevent hormonal cancers: breast and prostate cancers. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20070601
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro. British journal of pharmacology 20070601
The long-term effect of raloxifene on the genitourinary tract. Climacteric : the journal of the International Menopause Society 20070601
Time-dependent inactivation of P450 3A4 by raloxifene: identification of Cys239 as the site of apoprotein alkylation. Chemical research in toxicology 20070601
Differential impact of conventional and low-dose oral hormone therapy (HT), tibolone and raloxifene on functionality of the activated protein C system. Thrombosis and haemostasis 20070601
Efficacy of selective estrogen receptor modulators in nude mice bearing human transitional cell carcinoma. Urology 20070601
Raloxifene modulates pulmonary vascular reactivity in spontaneously hypertensive rats. Journal of cardiovascular pharmacology 20070601
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An analysis of which anti-osteoporosis therapeutic regimen would improve compliance in a population of elderly adults. Current medical research and opinion 20070201
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The effects of the selective estrogen receptor modulators, methyl-piperidino-pyrazole (MPP), and raloxifene in normal and cancerous endometrial cell lines and in the murine uterus. Molecular reproduction and development 20060801
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A Canadian observational study of the optimal method of transition from postmenopausal hormone therapy to raloxifene. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20060701
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Administration of raloxifene reduces sensorimotor and working memory deficits following traumatic brain injury. Behavioural brain research 20060630
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Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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Marked sexual dimorphism of lacrimal gland peroxidase in hamster: repression by androgens and estrogens. Biochemical and biophysical research communications 20060324
A 5-year study on the effect of hormone therapy, tibolone and raloxifene on vaginal bleeding and endometrial thickness. Maturitas 20060320
Antiresorptive agents, raloxifene, and PHARMAC. The New Zealand medical journal 20060310
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The effect of raloxifene after discontinuation of long-term alendronate treatment of postmenopausal osteoporosis. The Journal of clinical endocrinology and metabolism 20060301
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Effects of estrogen, raloxifene, and hormone replacement therapy on serum C-reactive protein and homocysteine levels. Maturitas 20060220
The effect of raloxifene and tibolone on the uterine blood flow and endometrial thickness: a transvaginal Doppler study. Maturitas 20060220
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Standardized bending and breaking test for the normal and osteoporotic metaphyseal tibias of the rat: effect of estradiol, testosterone, and raloxifene. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20060101
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An update on raloxifene. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Effects of 17beta-estradiol, progesterone, synthetic progestins, tibolone, and raloxifene on vascular endothelial growth factor and Thrombospondin-1 messenger RNA in breast cancer cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
[Hormonal replacement therapy and selective estrogen receptor modulators in prevention of cardiovascular disease]. Wiadomosci lekarskie (Warsaw, Poland : 1960) 20060101
Estrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1. BMC cardiovascular disorders 20060101
Prevention of breast cancer using selective oestrogen receptor modulators (SERMs). Breast cancer research : BCR 20060101
Commentary on Mobley and Others: importance of assumptions about VTE mortality in modeling the cost-effectiveness of osteoporosis therapies. Medical decision making : an international journal of the Society for Medical Decision Making 20060101
Biochemical markers of bone turnover in the clinical development of drugs for osteoporosis and metastatic bone disease: potential uses and pitfalls. Drugs 20060101
Raloxifene covalently bonded to titanium implants by interfacing with (3-aminopropyl)-triethoxysilane affects osteoblast-like cell gene expression. International journal of immunopathology and pharmacology 20060101
Estrogen receptor agonists and immune system in ovariectomized mice. International journal of immunopathology and pharmacology 20060101
The protection against trimetrexate cytotoxicity in human bone marrow by sequence-dependent administration of raloxifene, 5-fluorouracil/trimetrexate. Anticancer research 20060101
Raloxifene does not affect the changes in bone histomorphometric parameters induced by low dose tacrolimus in male rats. Acta poloniae pharmaceutica 20060101
[Current status of breast cancer chemoprevention]. Revista da Associacao Medica Brasileira (1992) 20060101
Is raloxifene ready to be used for prevention of breast cancer? International journal of fertility and women's medicine 20060101
[Osteoporosis treatment in Portugal: trends and geographical variation]. Acta medica portuguesa 20060101
ERE-independent ERalpha target genes differentially expressed in human breast tumors. Molecular and cellular endocrinology 20051221
Does raloxifene treatment influence back pain and disability among postmenopausal women with osteoporosis? European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20051201
Changes in RANKL/OPG/RANK gene expression in peripheral mononuclear cells following treatment with estrogen or raloxifene. Steroids 20051201
Baseline characteristics of menopausal women with coronary heart disease in cardiovascular outcomes clinical trials of menopausal hormone therapy or raloxifene. Contemporary clinical trials 20051201
A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20051201
Who will benefit from treatment with selective estrogen receptor modulators (SERMs)? Best practice & research. Clinical rheumatology 20051201
Raloxifene for postmenopausal women with systemic lupus erythematosus: a pilot randomized controlled study. Arthritis and rheumatism 20051201
Effect of raloxifene on aortic elasticity in healthy postmenopausal women. American heart journal 20051201
Procoagulant state after raloxifene therapy in postmenopausal women. Fertility and sterility 20051201
Therapeutic dosages of raloxifene do not modify myeloperoxidase and F2alpha-isoprostane levels in postmenopausal women. Fertility and sterility 20051201
The effect of raloxifene therapy on the risk of new clinical vertebral fractures at three and six months: a secondary analysis of the MORE trial. Current medical research and opinion 20051201
High risk of osteopenia and bone derangement in postsurgical patients with craniopharyngiomas, pituitary adenomas and other parasellar lesions. Endocrine journal 20051201
A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats. Journal of medicinal chemistry 20051103
Estrogenic regulation of tissue factor and tissue factor pathway inhibitor in platelets. American journal of physiology. Heart and circulatory physiology 20051101
Expression profiling of rat femur revealed suppression of bone formation genes by treatment with alendronate and estrogen but not raloxifene. Molecular pharmacology 20051101
Ospemifene inhibits the growth of dimethylbenzanthracene-induced mammary tumors in Sencar mice. The Journal of steroid biochemistry and molecular biology 20051101
[Implications of estrogens and their receptors for the development and progression of prostate cancer]. Der Pathologe 20051101
Combination teriparatide and raloxifene therapy for postmenopausal osteoporosis: results from a 6-month double-blind placebo-controlled trial. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20051101
A rational approach to evidence gaps in the management of osteoporosis. The American journal of medicine 20051101
What can be done about bone loss and what are the current treatments for it? Health news (Waltham, Mass.) 20051101
The role of non-calcemic analogs of vitamin D in differentiation of cultured rat bone marrow into osteoblast-like cells: age and sex differences. Journal of endocrinological investigation 20051101
Comparing raloxifene with continuous combined estrogen-progestin therapy in postmenopausal women: Review of Euralox 1. Maturitas 20051016
Modulator recognition factor 1, an AT-rich interaction domain family member, is a novel corepressor for estrogen receptor alpha. Molecular endocrinology (Baltimore, Md.) 20051001
HPLC analysis of raloxifene hydrochloride and its application to drug quality control studies. Pharmacological research 20051001
The effects of short-term raloxifene therapy on fibrinolysis markers: TAFI, tPA, and PAI-1. Acta obstetricia et gynecologica Scandinavica 20051001
The effects of 12 weeks of HMR 3339, a novel selective estrogen receptor modulator, on markers of coagulation and fibrinolysis: a randomized, placebo-controlled, double-blind, dose-ranging study in healthy postmenopausal women. American journal of obstetrics and gynecology 20051001
Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: a putative role for the epidermal growth factor receptor ligand amphiregulin. Journal of the Society for Gynecologic Investigation 20051001
Activity of estradiol and selective estrogen receptor modulators in the mouse N20.1 oligodendrocyte/astrocytes cell line. Neuro endocrinology letters 20051001
Review of treatment modalities for postmenopausal osteoporosis. Southern medical journal 20051001
[Modification of C3 and C4 levels after the administration of conjugated estrogens plus medroxiprogesterone or raloxifene in postmenopausal women]. Ginecologia y obstetricia de Mexico 20051001
A comparison of raloxifene and calcium plus vitamin D on vaginal atrophy after discontinuation of long-standing postmenopausal hormone therapy in osteoporotic women. A randomized, masked-evaluator, one-year, prospective study. Maturitas 20050916
Bazedoxifene acetate: a selective estrogen receptor modulator with improved selectivity. Endocrinology 20050901
Effects of oestrogen receptor-active compounds on lipid metabolism. Diabetes, obesity & metabolism 20050901
Skeletal effects of raloxifene after 8 years: results from the continuing outcomes relevant to Evista (CORE) study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050901
Analysis of protein covalent modification by xenobiotics using a covert oxidatively activated tag: raloxifene proof-of-principle study. Chemical research in toxicology 20050901
Safety assessment of raloxifene over eight years in a clinical trial setting. Current medical research and opinion 20050901
[Effects of raloxifene on bone biomarkers in postmenopausal women on maintenance haemodialysis]. Clinical calcium 20050901
Apoptosis and proliferation in breast cancer cells, cultured in vitro: effects of SERMs. Climacteric : the journal of the International Menopause Society 20050901
The selective estrogen receptor modulators, tamoxifen and raloxifene, impair dendritic cell differentiation and activation. Journal of immunology (Baltimore, Md. : 1950) 20050815
Impact of incident vertebral fractures on health related quality of life (HRQOL) in postmenopausal women with prevalent vertebral fractures. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20050801
BsmI vitamin D receptor genotypes influence the efficacy of antiresorptive treatments in postmenopausal osteoporotic women. A 1-year multicenter, randomized and controlled trial. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20050801
Raloxifene, a selective estrogen receptor modulator, reduces carrageenan-induced acute inflammation in normal and ovariectomized rats. Endocrinology 20050801
Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals 20050801
Vitamin D insufficiency does not affect bone mineral density response to raloxifene. The Journal of clinical endocrinology and metabolism 20050801
Effects of raloxifene, hormone therapy, and soy isoflavone on serum high-sensitive C-reactive protein in postmenopausal women. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20050801
Potential of endogenous estrogen receptor beta to influence the selective ER modulator ERbeta complex. International journal of oncology 20050801
Effect of estradiol and raloxifene on MUC1 expression and adhesive properties of Ishikawa cells. Oncology reports 20050801
Raloxifene and vitamin K2 combine to improve the femoral neck strength of ovariectomized rats. Calcified tissue international 20050801
Differing patterns of antiresorptive pharmacotherapy in nursing facility residents and community dwellers. Journal of the American Geriatrics Society 20050801
Raloxifene increases serum leptin levels in postmenopausal women: a prospective study. American journal of obstetrics and gynecology 20050801
Estrogen and extracellular matrix influence human gingival fibroblast proliferation and protein production. Journal of periodontology 20050801
Altered level of apurinic/apyrimidinic endonuclease/redox factor-1 (APE/REF-1) mRNA in the hippocampus of ovariectomized rats treated by raloxifene against kainic acid. Clinical and experimental pharmacology & physiology 20050801
A short-incubation reporter-gene assay for high-throughput screening of estrogen receptor-alpha antagonists. Assay and drug development technologies 20050801
[Selective estrogen receptors modulators (SERMs): biochemistry, pharmacology, and clinical use in gynecology]. Ginecologia y obstetricia de Mexico 20050801
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening. Journal of medicinal chemistry 20050728
Comparison of effects of the rise in serum testosterone by raloxifene and oral testosterone on serum insulin-like growth factor-1 and insulin-like growth factor binding protein-3. Maturitas 20050716
Differential effects of estrogen receptor antagonists on pituitary lactotroph proliferation and prolactin release. Molecular and cellular endocrinology 20050715
Differential effects of 17beta-estradiol and raloxifene on VSMC phenotype and expression of osteoblast-associated proteins. American journal of physiology. Endocrinology and metabolism 20050701
Raloxifene relaxes rat intrarenal arteries by inhibiting Ca2+ influx. American journal of physiology. Renal physiology 20050701
Anticancer multidrug resistance mediated by MRP1: recent advances in the discovery of reversal agents. Medicinal research reviews 20050701
Comparison of the metabolic effects of raloxifene and oral estrogen in postmenopausal and growth hormone-deficient women. The Journal of clinical endocrinology and metabolism 20050701
Effect of raloxifene on serum triglycerides in women with a history of hypertriglyceridemia while on oral estrogen therapy. Diabetes care 20050701
Effects of raloxifene and low-dose simvastatin coadministration on plasma lipids in postmenopausal women with primary hypercholesterolemia. Metabolism: clinical and experimental 20050701
Antiproliferative and proapoptotic effects of raloxifene on uterine leiomyomas in postmenopausal women. Fertility and sterility 20050701
[Effect of raloxifene and estradiol on the biological function and osteoprotegerin expression of osteoblasts in vitro]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050701
Raloxifene for prevention of osteoporotic fractures. American family physician 20050701
Evidence of improved serum fatty acid profile of postmenopausal women receiving atorvastatin and raloxifene. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20050701
Endometrial lesions causing uterine bleeding in postmenopausal women receiving raloxifene. Maturitas 20050616
Mouse estrogen receptor beta isoforms exhibit differences in ligand selectivity and coactivator recruitment. Biochemistry 20050607
Inhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by raloxifene, an antiestrogen with anti-androgen action, but not nimesulide, a selective cyclooxygenase-2 inhibitor. Carcinogenesis 20050601
Species- and disposition model-dependent metabolism of raloxifene in gut and liver: role of UGT1A10. Drug metabolism and disposition: the biological fate of chemicals 20050601
Estrogen and raloxifene, a selective estrogen receptor modulator, ameliorate renal damage in db/db mice. The American journal of pathology 20050601
A systematic review and economic evaluation of alendronate, etidronate, risedronate, raloxifene and teriparatide for the prevention and treatment of postmenopausal osteoporosis. Health technology assessment (Winchester, England) 20050601
[Raloxifene and bone quality issues]. Clinical calcium 20050601
Raloxifene promotes prostacyclin release in human endothelial cells through a mechanism that involves cyclooxygenase-1 and -2. Fertility and sterility 20050601
Breast cancer chemoprevention: a review of selective estrogen receptor modulators. Clinical journal of oncology nursing 20050601
Effect of tamoxifen and raloxifene on cholesterol transformation to bile acids in ovariectomized rats. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050601
Raloxifene for hormone replacement therapy (HRT). The New Zealand medical journal 20050506
Safety profile of raloxifene as used in general practice in England: results of a prescription-event monitoring study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20050501
Differential effects of 17beta-estradiol, conjugated equine estrogen, and raloxifene on mRNA expression, aggregation, and secretion in platelets. American journal of physiology. Heart and circulatory physiology 20050501
Suppression of experimental autoimmune encephalomyelitis using estrogen receptor-selective ligands. The Journal of endocrinology 20050501
Malignant mixed mullerian tumor of the uterus in a patient taking raloxifene. Obstetrics and gynecology 20050501
Magnetic resonance spectroscopic comparison of the effects of resveratrol (3,4',5-trihydroxy stilbene) to conjugated equine estrogen, tibolone and raloxifene on ovariectomized rat brains. European journal of obstetrics, gynecology, and reproductive biology 20050501
New help for old bones. Nursing 20050501
Estrogen increases collagen I and III mRNA expression in the pelvic support tissues of the rhesus macaque. American journal of obstetrics and gynecology 20050501
Effectiveness and safety of raloxifene in post-menopausal females. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20050501
Raloxifene and colorectal cancer. Journal of women's health (2002) 20050501
Anti-inflammatory effect of selective estrogen receptor modulators (SERMs) in microglial cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050501
Differential effects of alternatives to hormone replacement therapy in postmenopausal healthy women. Danish medical bulletin 20050501
Efficient access to 2-aryl-3-substituted benzo[b]thiophenes. The Journal of organic chemistry 20050429
Effect of raloxifene and hormone therapy on serum markers of brain and whole-body cholesterol metabolism in postmenopausal women. Maturitas 20050411
Serum androgen levels and insulin resistance in postmenopausal women: association with hormone therapy, tibolone and raloxifene. Maturitas 20050411
[Raloxifene for the treatment of osteoporosis]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050410
Re: Continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. Journal of the National Cancer Institute 20050406
25-hydroxyvitamin D3-1alpha-hydroxylase is expressed in human vascular smooth muscle cells and is upregulated by parathyroid hormone and estrogenic compounds. Circulation 20050405
Chronic estrogenic drug treatment increases preproenkephalin mRNA levels in the rat striatum and nucleus accumbens. Psychoneuroendocrinology 20050401
Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus. Biology of reproduction 20050401
Searching for methods to detect, prevent, and treat Alzheimer's disease. The American journal of psychiatry 20050401
Effect of raloxifene on prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial. The American journal of psychiatry 20050401
Raloxifene pharmacokinetics in males with normal and impaired renal function. British journal of clinical pharmacology 20050401
[Effects of estrogen and selective estrogen receptor modulators on osteoporosis]. Clinical calcium 20050401
[SERMs: an update for clinicians]. Clinical calcium 20050401
Effect of tamoxifen, raloxifen and tibolon on bile components in ovariectomized rats. European journal of obstetrics, gynecology, and reproductive biology 20050401
Treatment of adolescents with gynecomastia. The Journal of pediatrics 20050401
Transcriptional activation of the oxytocin promoter by oestrogens uses a novel non-classical mechanism of oestrogen receptor action. Journal of neuroendocrinology 20050401
Molecular mechanism of action of selective estrogen receptor modulator in target tissues. Endocrine journal 20050401
Anti-growth factor activities of benzothiophenes in human breast cancer cells. The Journal of steroid biochemistry and molecular biology 20050401
Hormone replacement therapy--differing guidelines. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20050401
Estradiol-induced ezrin overexpression in ovarian cancer: a new signaling domain for estrogen. Cancer letters 20050318
Sodium nitroprusside-induced osteoblast apoptosis is mediated by long chain ceramide and is decreased by raloxifene. Biochemical pharmacology 20050315
Effects of raloxifene on serum malondialdehyde, erythrocyte superoxide dismutase, and erythrocyte glutathione peroxidase levels in healthy postmenopausal women. Maturitas 20050314
Selective estrogen-receptor modulators for primary prevention of breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050310
Raloxifene relaxes rat pulmonary arteries and veins: roles of gender, endothelium, and antagonism of Ca2+ influx. The Journal of pharmacology and experimental therapeutics 20050301
The putative tumor suppressor deleted in malignant brain tumors 1 is an estrogen-regulated gene in rodent and primate endometrial epithelium. Endocrinology 20050301
Estrogen and selective estrogen receptor modulators exert neuroprotective effects and stimulate the expression of selective Alzheimer's disease indicator-1, a recently discovered antiapoptotic gene, in human neuroblast long-term cell cultures. The Journal of clinical endocrinology and metabolism 20050301
Benzothiophenes containing a piperazine side chain as selective ligands for the estrogen receptor alpha and their bioactivities in vivo. Bioorganic & medicinal chemistry letters 20050301
Raloxifene exposure enhances brain activation during memory performance in healthy elderly males; its possible relevance to behavior. NeuroImage 20050301
Oral antiresorptive therapy. Current rheumatology reports 20050301
Incidence of urinary incontinence in postmenopausal women treated with raloxifene or estrogen. Menopause (New York, N.Y.) 20050301
Effects of ospemifene and raloxifene on hormonal status, lipids, genital tract, and tolerability in postmenopausal women. Menopause (New York, N.Y.) 20050301
Changes in 5-HT1A receptor binding and G-protein activation in the rat brain after estrogen treatment: comparison with tamoxifen and raloxifene. Journal of psychiatry & neuroscience : JPN 20050301
Effects of conjugated equine estrogens or raloxifene on lipid profile, coagulation and fibrinolysis factors in postmenopausal women. Climacteric : the journal of the International Menopause Society 20050301
[Selective estrogen receptor modulator (SERM)]. Nihon rinsho. Japanese journal of clinical medicine 20050301
[Treatment of osteoporosis with antiresorptive drugs]. Ugeskrift for laeger 20050221
[Osteoporosis in the elderly--diagnosis and treatment]. MMW Fortschritte der Medizin 20050217
Antidepressant augmentation with raloxifene. Journal of clinical psychopharmacology 20050201
Raloxifene improves bone mass in osteopenic women with primary biliary cirrhosis: results of a pilot study. Liver international : official journal of the International Association for the Study of the Liver 20050201
Methyl mercury influences growth-related signaling in MCF-7 breast cancer cells. Environmental toxicology 20050201
Progressive pigmentary purpura related to raloxifene. Saudi medical journal 20050201
Beneficial effects of raloxifene and atorvastatin on serum lipids. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20050201
Estradiol and raloxifene protect cultured SN4741 neurons against oxidative stress. Neuroscience letters 20050120
Ab initio quantum mechanical study of the binding energies of human estrogen receptor alpha with its ligands: an application of fragment molecular orbital method. Journal of computational chemistry 20050115
Repercussions of raloxifen, tamoxifen and estrogen on aortic atherosclerotic lesions of female rabbits submitted to ovariectomy and hypercholesterol diet. Maturitas 20050110
Prevention of hormone-related cancers: breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050110
Gene expression changes induced by estrogen and selective estrogen receptor modulators in primary-cultured human endometrial cells: signals that distinguish the human carcinogen tamoxifen. Toxicology 20050105
Protection of bone mass by estrogens and raloxifene during exercise-induced weight Loss. The Journal of clinical endocrinology and metabolism 20050101
Examination of 209 drugs for inhibition of cytochrome P450 2C8. Journal of clinical pharmacology 20050101
Raloxifene does not prevent fibrinogen oxidation in vitro. Medical science monitor : international medical journal of experimental and clinical research 20050101
Gonadotrope oestrogen receptor-alpha and -beta and progesterone receptor immunoreactivity after ovariectomy and exposure to oestradiol benzoate, tamoxifen or raloxifene in the rat: correlation with LH secretion. The Journal of endocrinology 20050101
TAS-108, a novel oral steroidal antiestrogenic agent, is a pure antagonist on estrogen receptor alpha and a partial agonist on estrogen receptor beta with low uterotrophic effect. Clinical cancer research : an official journal of the American Association for Cancer Research 20050101
Cost-effectiveness of raloxifene in the UK: an economic evaluation based on the MORE study. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20050101
CORE breast-cancer prevention trial. The Lancet. Oncology 20050101
[Raloxifene hydrochloride (Evista Tablet 60 mg) for postmenopausal osteoporosis: mode of action and clinical efficacy]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20050101
Restoration of endothelial function via enhanced nitric oxide synthesis after long-term treatment of raloxifene in adult hypertensive rats. Arzneimittel-Forschung 20050101
Estrogen receptor (ER) gene polymorphism may predict the bone mineral density response to raloxifene in postmenopausal women on chronic hemodialysis. Renal failure 20050101
Interleukin-18 (IL-18) and matrix metalloproteinase-9 (MMP-9) in post-menopausal osteoporosis. Archives of gerontology and geriatrics 20050101
Short-term effects of estrogen, tamoxifen and raloxifene on hemostasis: a randomized-controlled study and review of the literature. Thrombosis research 20050101
Year-by-year analysis of cardiovascular events in the Multiple Outcomes of Raloxifene Evaluation (MORE) trial. Current medical research and opinion 20050101
Pharmacological management of severe postmenopausal osteoporosis. Drugs & aging 20050101
Microdamage accumulation in the monkey vertebra does not occur when bone turnover is suppressed by 50% or less with estrogen or raloxifene. Journal of bone and mineral metabolism 20050101
Raloxifene and teriparatide (hPTH 1-34) have complementary effects on the osteopenic skeleton of ovariectomized rats. Journal of bone and mineral metabolism 20050101
Differential effects of genistein, estradiol and raloxifene on rat osteoclasts in vitro. Pharmacological reports : PR 20050101
Effects of resveratrol, raloxifene, tibolone and conjugated equine estrogen on vaginal squamous cell maturation of ovariectomized rats. Gynecologic and obstetric investigation 20050101
Vascular events in the Multiple Outcomes of Raloxifene Evaluation (MORE) trial: incidence, patient characteristics, and effect of raloxifene. Menopause (New York, N.Y.) 20050101
Benefit-risk assessment of raloxifene in postmenopausal osteoporosis. Drug safety 20050101
Similar proportions of women lose bone mineral density with raloxifene or alendronate treatment. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry 20050101
Validation of rat endometriosis model by using raloxifene as a positive control for the evaluation of novel SERM compounds. Journal of investigative surgery : the official journal of the Academy of Surgical Research 20050101
Interleukin-6 and flow-mediated dilatation as markers of increased vascular inflammation in women receiving hormone therapy. Menopause (New York, N.Y.) 20050101
Hormonal environment in the induction of breast cancer in castrated rats using dimethylbenzanthracene: influence of the presence or absence of ovarian activity and of treatment with estradiol, tibolone, and raloxifene. Menopause (New York, N.Y.) 20050101
Effects of raloxifene on body fat distribution and lipid profile in healthy post-menopausal women. Journal of endocrinological investigation 20050101
Women's decision making about whether or not to use breast cancer chemoprevention. Women & health 20050101
Counterfeit drug warning. FDA consumer 20050101
Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis. Arthritis research & therapy 20050101
Decision rule based multiplicity adjustment strategy. Clinical trials (London, England) 20050101
Anabolic therapy for osteoporosis. International journal of fertility and women's medicine 20050101
Aggressive angiomyxoma of the perineum. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101
Raloxifene and cardiovascular health: its relationship to lipid and glucose metabolism, hemostatic and inflammation factors and cardiovascular function in postmenopausal women. Current pharmaceutical design 20050101
Identifying methodologies in the assessment of treatment effects on the repeated occurrences of hot flashes in postmenopausal women. Clinical trials (London, England) 20050101
Expression of steroid receptors in intact rat uterus, mammary gland, and liver treated with selective estrogen receptor modulators and conjugated equine estrogens. Advances in therapy 20050101
Raloxifene: bone and cardiovascular effects. Journal of endocrinological investigation 20050101
[Raloxifene (Evista) in the treatment of postmenopausal osteoporosis--the profile of the patient]. Reumatizam 20050101
Chemoprevention of breast cancer in postmenopausal women. Breast disease 20050101
Treatment of Postmenopausal Breast Cancer with Selective Estrogen Receptor Modulators (SERMs). Breast disease 20050101
Effects of hormone replacement therapy or raloxifene on ambulatory blood pressure and arterial stiffness in treated hypertensive postmenopausal women. The American journal of cardiology 20041201
Defining the role of raloxifene for the prevention of breast cancer. Journal of the National Cancer Institute 20041201
Continuing outcomes relevant to Evista: breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of raloxifene. Journal of the National Cancer Institute 20041201
[Evaluation of osteoporosis treatment efficacy by bone mass measurement]. Clinical calcium 20041201
Raloxifene modulates interleukin-6 and tumor necrosis factor-alpha synthesis in vivo: results from a pilot clinical study. The Journal of clinical endocrinology and metabolism 20041201
HMR 3339, a novel selective estrogen receptor modulator, reduces total cholesterol, low-density lipoprotein cholesterol, and homocysteine in healthy postmenopausal women. Fertility and sterility 20041201
Both estrogen and raloxifene protect against beta-amyloid-induced neurotoxicity in estrogen receptor alpha-transfected PC12 cells by activation of telomerase activity via Akt cascade. The Journal of endocrinology 20041201
Predictors of hot flushes in postmenopausal women who receive raloxifene therapy. American journal of obstetrics and gynecology 20041201
Oral antiresorptive therapy. Current osteoporosis reports 20041201
Selective estrogen receptor modulators prevent neointima formation after vascular injury. Molecular and cellular endocrinology 20041130
Effects of ovarian steroids and raloxifene on proteins that synthesize, transport, and degrade serotonin in the raphe region of macaques. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20041101
Selective oestrogen receptor modulators in desmoid tumours. Expert opinion on investigational drugs 20041101
[Menopause in 2004: 'hormone replacement therapy' is not what it used to be anymore]. La Revue de medecine interne 20041101
Effect of HMR 3339, a novel selective estrogen receptor modulator, on C-reactive protein levels in healthy postmenopausal women. The American journal of cardiology 20041101
Treatment with raloxifene for 2 years increases vertebral bone mineral density as measured by volumetric quantitative computed tomography. Bone 20041101
Effects of 17beta-estradiol, tamoxifen and raloxifene on the protein and mRNA expression of interleukin-6, transforming growth factor-beta1 and insulin-like growth factor-1 in primary human osteoblast cultures. Journal of endocrinological investigation 20041101
[Selective estrogen receptor modulators]. Polskie Archiwum Medycyny Wewnetrznej 20041101
Endogenous estrogen levels affect sexual function in elderly post-menopausal women. Maturitas 20041015
Safety and adverse effects associated with raloxifene: multiple outcomes of raloxifene evaluation. Obstetrics and gynecology 20041001
Raloxifene reduces risk of vertebral fractures [corrected] in postmenopausal women regardless of prior hormone therapy. The Journal of family practice 20041001
Endocrine therapy for early breast cancer. Expert review of anticancer therapy 20041001
In vivo properties of the urinary bladder wall and their modulation by estradiol and raloxifene in a rat model. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20041001
Pharmacologic prevention of osteoporotic fractures. American family physician 20041001
Effect of hormone replacement therapy on the elemental contents of uterine tissue. Biological trace element research 20041001
Treating osteoporosis in post-menopausal women: a case approach. Cleveland Clinic journal of medicine 20041001
[Hormone therapy for uterine corpus cancer--introduction]. Nihon rinsho. Japanese journal of clinical medicine 20041001
[SERM & bone metabolism: protective effects of SERM against fracture risk and its long-term beneficial effects]. Clinical calcium 20041001
[Contribution of bone quality to fracture risk]. Clinical calcium 20041001
[Relationship between changes in biochemical markers of bone turnover and prediction value of fracture risk]. Clinical calcium 20041001
[Additional effect of SERM: mammary gland]. Clinical calcium 20041001
[Effects of raloxifene on other organs without bone: uterus]. Clinical calcium 20041001
[Cardiovascular effects of SERM]. Clinical calcium 20041001
[Additional effect of SERM: central nervous system]. Clinical calcium 20041001
[Defining the role of raloxifene as a therapeutic agent for postmenopausal osteoporosis: focus on its pharmacological properties]. Clinical calcium 20041001
[Effects of SERM on breast cancer and cardiovascular disease: making a comparison between raloxifene use and hormone replacement therapy on the risks of the diseases]. Clinical calcium 20041001
[SERM and quality of bone]. Clinical calcium 20041001
[Safety profile of raloxifene]. Clinical calcium 20041001
[Which is the better choice, estrogen or SERMs in postmenopausal women?]. Clinical calcium 20041001
[Who are the candidates for the treatment by raloxifen ?]. Clinical calcium 20041001
Effect of raloxifene on activated protein C (APC) resistance in postmenopausal women and on APC resistance and homocysteine levels in elderly men: two randomized placebo-controlled studies. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20041001
[Menopausal hormonal therapies: impact on mammographic breast density]. Journal de radiologie 20041001
Latest innovation in the treatment of osteoporosis: SERMs and the role of parathyroid hormone. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20041001
Differential effects of raloxifene and tamoxifen on the expression of estrogen receptors and antigen Ki-67 in human endometrial adenocarcinoma cell line. Oncology reports 20040901
Raloxifene treatment is associated with increased serum estradiol and decreased bone remodeling in healthy middle-aged men with low sex hormone levels. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040901
Comparison of fracture, cardiovascular event, and breast cancer rates at 3 years in postmenopausal women with osteoporosis. Journal of the American Geriatrics Society 20040901
Raloxifene and hormone replacement therapy increase arachidonic acid and docosahexaenoic acid levels in postmenopausal women. The Journal of endocrinology 20040901
Effect of hormone therapy and raloxifene on serum VE-cadherin in postmenopausal women. Fertility and sterility 20040901
Spectrophotometric analysis of raloxifene hydrochloride in pure and pharmaceutical formulations. Die Pharmazie 20040901
Management of osteoporosis in Hong Kong. Clinical calcium 20040901
Diabetes, impaired fasting glucose, and development of cognitive impairment in older women. Neurology 20040824
Arzoxifene: a promising new selective estrogen receptor modulator for clinical chemoprevention of breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20040815
Structural basis for the deactivation of the estrogen-related receptor gamma by diethylstilbestrol or 4-hydroxytamoxifen and determinants of selectivity. The Journal of biological chemistry 20040806
Risk-benefit profile for raloxifene: 4-year data From the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040801
Raloxifene and its role in breast cancer prevention. Expert review of anticancer therapy 20040801
Effects of clomiphene and raloxifene on gonadotrophin secretion in postmenopausal women: evidence of nongenomic action. Clinical endocrinology 20040801
Raloxifene to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer: a randomized controlled trial. The Journal of clinical endocrinology and metabolism 20040801
Effect of hormone therapy, tibolone and raloxifene on circulating vascular endothelial growth factor in Greek postmenopausal women. European journal of endocrinology 20040801
Effects of conjugated equine estrogen vs. raloxifene on serum insulin-like growth factor-i and insulin-like growth factor binding protein-3: a 2-year, double-blind, placebo-controlled study. Fertility and sterility 20040801
Gonadotropin-releasing hormone agonist with or without raloxifene: effects on cognition, mood, and quality of life. Fertility and sterility 20040801
Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues. The Journal of steroid biochemistry and molecular biology 20040801
National trends in osteoporosis visits and osteoporosis treatment, 1988-2003. Archives of internal medicine 20040726
Compliance with drug therapies for the treatment and prevention of osteoporosis. Maturitas 20040715
Raloxifene lowers ischaemia susceptibility by increasing nitric oxide generation in the heart of ovariectomized rats in vivo. European journal of pharmacology 20040714
Lead identification of a potent benzopyranone selective estrogen receptor modulator. Bioorganic & medicinal chemistry letters 20040705
Disposition mechanisms of raloxifene in the human intestinal Caco-2 model. The Journal of pharmacology and experimental therapeutics 20040701
Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats. Endocrinology 20040701
Effects of raloxifene and estradiol on hippocampal acetylcholine release and spatial learning in the rat. Psychoneuroendocrinology 20040701
Raloxifene relaxes rat cerebral arteries in vitro and inhibits L-type voltage-sensitive Ca2+ channels. Stroke 20040701
A new selective estrogen receptor modulator HMR-3339 fully corrects bone alterations induced by ovariectomy in adult rats. Bone 20040701
Effect of raloxifene on urinary incontinence: a randomized controlled trial. Obstetrics and gynecology 20040701
Beneficial effects of raloxifene and tamoxifen in the treatment of pubertal gynecomastia. The Journal of pediatrics 20040701
Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature. The Journal of clinical endocrinology and metabolism 20040701
Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones. Chemical research in toxicology 20040701
Effect of raloxifene on the incidence of elevated low density lipoprotein (LDL) and achievement of LDL target goals in postmenopausal women. Current medical research and opinion 20040701
Effects of raloxifene hydrochloride on bone mineral density, bone metabolism and serum lipids in Chinese postmenopausal women with osteoporosis: a multi-center, randomized, placebo-controlled clinical trial. Chinese medical journal 20040701
Estrogen-like activity of licorice root constituents: glabridin and glabrene, in vascular tissues in vitro and in vivo. The Journal of steroid biochemistry and molecular biology 20040701
Raloxifene is not associated with biologically relevant changes in hot flushes in postmenopausal women for whom therapy is appropriate. American journal of obstetrics and gynecology 20040701
Long-term effectiveness and safety of GnRH agonist plus raloxifene administration in women with uterine leiomyomas. Human reproduction (Oxford, England) 20040601
Differential effects of estradiol, raloxifene and tamoxifen on estrogen receptor expression in cultured human skin fibroblasts. International journal of molecular medicine 20040601
Raloxifene improves coronary perfusion, cardiac contractility, and myocardial metabolism in the ischemic heart: role of phosphatidylinositol 3-kinase/Akt pathway. Journal of cardiovascular pharmacology 20040601
Does raloxifene inhibit the growth of uterine fibroids? Fertility and sterility 20040601
Effects of raloxifene hydrochloride on endometrial cancer cells in vitro. Gynecologic oncology 20040601
Beneficial effects of raloxifene and atorvastatin on serum lipids and HDL phospholipids levels of postmenopausal women. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20040601
Role of raloxifene in breast cancer prevention in postmenopausal women: clinical evidence and potential mechanisms of action. Clinical therapeutics 20040601
Comparison of raloxifene and atorvastatin effects on serum lipids composition of healthy post-menopausal women. Molecular and cellular biochemistry 20040601
Comparative vascular effects of hormone replacement therapy and raloxifene in women at increased cardiovascular risk. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040601
A reappraisal of therapeutic approaches to osteoporosis. Aging clinical and experimental research 20040601
Effects of raloxifene on mood, sleep, libido and cognitive function in postmenopausal healthy women: a pilot study. Maturitas 20040528
Prevention of osteoporosis and osteoporotic fractures in postmenopausal women: recommendation statement from the Canadian Task Force on Preventive Health Care. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20040525
[Risk of osteoporosis in postmenopausal women. When is bone density measurement indicated?]. MMW Fortschritte der Medizin 20040520
Raloxifene acutely suppresses ventricular myocyte contractility through inhibition of the L-type calcium current. British journal of pharmacology 20040501
Differential effects of teriparatide on BMD after treatment with raloxifene or alendronate. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040501
Associations between baseline risk factors and vertebral fracture risk in the Multiple Outcomes of Raloxifene Evaluation (MORE) Study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040501
The effect of raloxifene on markers of bone turnover in older women living in long-term care facilities. Journal of the American Geriatrics Society 20040501
Value of SERMs in postmenopausal women. Lancet (London, England) 20040501
Uterine effects of estrogen plus progestin therapy and raloxifene: adjudicated results from the EURALOX study. Obstetrics and gynecology 20040501
Cardiovascular effects of raloxifene: the arterial and venous systems. American heart journal 20040501
Effects of the selective estrogen receptor modulator LY117018 on growth hormone secretion: In vitro studies. Metabolism: clinical and experimental 20040501
Refining clinical practice: transforming science research into the art of medicine. Annals of the Academy of Medicine, Singapore 20040501
Inhibition of low-density lipoprotein and high-density lipoprotein oxidation by raloxifene. Journal of women's health (2002) 20040501
Effect of raloxifene and its interaction with human PTH on bone formation. Journal of endocrinological investigation 20040501
Effect of hormone replacement therapy, tibolone and raloxifene on serum lipids, apolipoprotein A1, apolipoprotein B and lipoprotein(a) in Greek postmenopausal women. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040501
[Bone quality in treatment with raroxifene ]. Clinical calcium 20040501
A comparison of the effects of raloxifene and conjugated equine estrogen on bone and lipids in healthy postmenopausal women. Archives of internal medicine 20040426
Cloning and functional characterization of PELP1/MNAR promoter. Gene 20040414
Alendronate produces greater effects than raloxifene on bone density and bone turnover in postmenopausal women with low bone density: results of EFFECT (Efficacy of FOSAMAX versus EVISTA Comparison Trial) International. Journal of internal medicine 20040401
Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens. Journal of molecular endocrinology 20040401
Raloxifene decreases serum IGF-I in male patients with active acromegaly. European journal of endocrinology 20040401
Effects of raloxifene on gonadotrophins, sex hormones, bone turnover and lipids in healthy elderly men. European journal of endocrinology 20040401
Veralipride administered in combination with raloxifene decreases hot flushes and improves bone density in early postmenopausal women. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040401
[Bone quality and raloxifene]. Clinical calcium 20040401
Raloxifene therapy does not affect uterine blood flow in postmenopausal women: a transvaginal Doppler study. Maturitas 20040315
Development and validation of a quantitative assay for raloxifene by capillary electrophoresis. Journal of pharmaceutical and biomedical analysis 20040310
[Effects of different treatments for osteoporosis on prevention of fractures: toward and individualized and economic approach]. Praxis 20040310
New ways with old bones. Osteoporosis researchers look for drugs to replace hormone replacement therapy. Lancet (London, England) 20040306
Hormone alternative doesn't worsen vasomotor symptoms or impact urinary incontinence in post-menopausal women. Report on medical guidelines & outcomes research 20040305
[Delaying degeneration or promoting regeneration. 2 successful strategies in osteoporosis]. MMW Fortschritte der Medizin 20040304
Endocrine prevention of breast cancer using selective oestrogen receptor modulators (SORMs). Best practice & research. Clinical endocrinology & metabolism 20040301
Estradiol and selective estrogen receptor modulators differentially regulate target genes with estrogen receptors alpha and beta. Molecular biology of the cell 20040301
Effects of a long-term treatment with raloxifene on insulin sensitivity in postmenopausal women. Diabetologia 20040301
Osteoporosis: underrated, underdiagnosed and undertreated. The Medical journal of Australia 20040301
The impact of monitoring on adherence and persistence with antiresorptive treatment for postmenopausal osteoporosis: a randomized controlled trial. The Journal of clinical endocrinology and metabolism 20040301
Insights into the molecular biology of the estrogen receptor define novel therapeutic targets for breast cancer. European journal of endocrinology 20040301
Mechanisms for altered reproductive function in female rats following neonatal administration of raloxifene. European journal of endocrinology 20040301
Relationship between changes in biochemical markers of bone turnover and BMD to predict vertebral fracture risk. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040301
Selective estrogen receptor modulation: concept and consequences in cancer. Cancer cell 20040301
Osteoporosis--diagnosis, treatment and management. Australian family physician 20040301
[Evidence-based medicine and drug selection of osleoporosis prevention after menopause]. Zhonghua yi xue za zhi 20040217
[Effect of raloxifene hydrochloride on bone mineral density, bone metabolism and serum lipids in Chinese postmenopausal women with osteoporosis]. Zhonghua yi xue za zhi 20040217
Interplay between estrogen response element sequence and ligands controls in vivo binding of estrogen receptor to regulated genes. The Journal of biological chemistry 20040206
17beta-estradiol downregulates beta3-integrin expression in differentiating and mature human osteoclasts. Journal of cellular physiology 20040201
Raloxifene prevents cardiac hypertrophy and dysfunction in pressure-overloaded mice. Hypertension (Dallas, Tex. : 1979) 20040201
Lipid, glucose and homocysteine metabolism in women treated with a GnRH agonist with or without raloxifene. Human reproduction (Oxford, England) 20040201
Effect of raloxifene on urinary incontinence: a randomized controlled trial. Obstetrics and gynecology 20040201
Transition from estrogen-progestin to raloxifene in postmenopausal women: effect on vasomotor symptoms. Obstetrics and gynecology 20040201
Reduction in PINP, a marker of bone metabolism, with raloxifene treatment and its relationship with vertebral fracture risk. Bone 20040201
Raloxifene therapy in postmenopausal women is associated with a significant reduction in the concentration of serum vascular endothelial growth factor. Fertility and sterility 20040201
Progress in chemoprevention of breast cancer. Critical reviews in oncology/hematology 20040201
[MORE study(raloxifene)]. Nihon rinsho. Japanese journal of clinical medicine 20040201
[Raloxifene hydrochloride]. Nihon rinsho. Japanese journal of clinical medicine 20040201
[Prevention of fractures with therapeutic agents for osteoporosis]. Nihon rinsho. Japanese journal of clinical medicine 20040201
[Quality of life before and after medical treatments in osteoporosis patients]. Nihon rinsho. Japanese journal of clinical medicine 20040201
Compliance and satisfaction with raloxifene versus alendronate for the treatment of postmenopausal osteoporosis in clinical practice: An open-label, prospective, nonrandomized, observational study. Clinical therapeutics 20040201
Therapeutic targeting in the estrogen receptor hormonal pathway. Seminars in oncology 20040201
Comparative study of the short-term effects of a novel selective estrogen receptor modulator, ospemifene, and raloxifene and tamoxifen on rat uterus. The Journal of steroid biochemistry and molecular biology 20040201
Treatment with non-hypercalcemic analogs of 1,25-dihydroxyvitamin D3 increases responsiveness to 17beta-estradiol, dihydrotestosterone or raloxifene in primary human osteoblasts. The Journal of steroid biochemistry and molecular biology 20040201
Impact of the nuclear receptor coactivator AIB1 isoform AIB1-Delta3 on estrogenic ligands with different intrinsic activity. Oncogene 20040115
[Postmenopausal osteoporosis]. Orvosi hetilap 20040104
Raloxifene inhibits cholesterol aortic content but not atherosclerotic plaque size in oophorectomised cholesterol-fed rabbits. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20040101
Comparative analysis of oestrogen and raloxifene effects on the phospholipid composition of high density lipoproteins in healthy postmenopausal women. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20040101
Recurrent vulval fibroids--an unusual indication for selective oestrogen receptor modulators (SERMs). Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20040101
Impact of the selective estrogen receptor modulator, raloxifene, on neuronal survival and outgrowth following toxic insults associated with aging and Alzheimer's disease. Experimental neurology 20040101
Potent inhibition of human liver aldehyde oxidase by raloxifene. Drug metabolism and disposition: the biological fate of chemicals 20040101
Raloxifene prevents the growth of uterine leiomyomas in premenopausal women. Fertility and sterility 20040101
Raloxifene reduces procarboxypeptidase U, an antifibrinolytic marker. A 2-year randomized, placebo-controlled study in healthy early postmenopausal women. Menopause (New York, N.Y.) 20040101
[Raloxifene and breast: from the SERMs concept to its place in clinical practice]. Gynecologie, obstetrique & fertilite 20040101
Transition from estrogen therapy to raloxifene in postmenopausal women: effects on treatment satisfaction and the endometrium-a pilot study. Menopause (New York, N.Y.) 20040101
A one-year follow-up on the effects of raloxifene on thyroid function in postmenopausal women. Menopause (New York, N.Y.) 20040101
High glucose blocks the effects of estradiol on human vascular cell growth: differential interaction with estradiol and raloxifene. The Journal of steroid biochemistry and molecular biology 20040101
[Chemoprevention of breast cancer. Clinical trials in pharmacological prevention]. Medicina 20040101
The role of selective estrogen receptor modulators in the prevention of breast cancer: comparison of the clinical trials. The oncologist 20040101
Effects of raloxifene, one of the selective estrogen receptor modulators, on pituitary-ovary axis and prolactin in postmenopausal women. Endocrine 20040101
Effect of raloxifene on quality of life: a prospective study using the Utian Quality of Life (UQOL) Scale. Menopause (New York, N.Y.) 20040101
The effect of hormone therapy and raloxifene on serum matrix metalloproteinase-2 and -9 in postmenopausal women. Menopause (New York, N.Y.) 20040101
Estrogen receptor profiles: changes in mouse and rat mammary tumors by treatment with selective estrogen receptor modifiers. Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20040101
Once-weekly alendronate 70 mg and raloxifene 60 mg daily in the treatment of postmenopausal osteoporosis. Menopause (New York, N.Y.) 20040101
Raloxifene increases the capacity of serum to promote prostacyclin release in human endothelial cells: implication of COX-1 and COX-2. Menopause (New York, N.Y.) 20040101
Prevention of osteoporosis and uterine effects in post-menopausal women taking raloxifene for 5 years. Menopause (New York, N.Y.) 20040101
The effect of raloxifene on cognitive function in postmenopausal women: a randomized clinical trial. Connecticut medicine 20040101
Antiresorption therapy and reduction in fracture susceptibility in the osteoporotic elderly patient: open study. European review for medical and pharmacological sciences 20040101
Mood modifications with raloxifene and continuous combined estrogen plus progestin hormone therapy. International journal of fertility and women's medicine 20040101
Chemoprevention of breast cancer. Current problems in cancer 20040101
Hormone therapy and selective estrogen receptor modulators for prevention of coronary heart disease in postmenopausal women estrogen replacement from the cardiologist's perspective. Cardiology in review 20040101
[Compression vertebral fracture in osteoporosis--prevention and treatment]. Reumatizam 20040101
Health-economic comparison of three recommended drugs for the treatment of osteoporosis. International journal of clinical pharmacology research 20040101
[Selective estrogen receptor modulator]. Clinical calcium 20040101
Raloxifene rebound regression. Cancer investigation 20040101
Cost effectiveness of raloxifene in the treatment of osteoporosis in Sweden: an economic evaluation based on the MORE study. PharmacoEconomics 20040101
[Update 2004. Osteoporosis--management--current status]. Krankenpflege Journal 20040101
Hormone replacement therapy, selective estrogen receptor modulators, and tissue-specific compounds: cardiovascular effects and clinical implications. Treatments in endocrinology 20040101
Identification of transcriptional biomarkers induced by SERMS in human endometrial cells using multivariate analysis of DNA microarrays. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101
[New prevention strategies against breast cancer and cervical carcinoma. What can you advice to your patients]. MMW Fortschritte der Medizin 20031211
[Therapy of postmenopausal osteoporosis]. Der Orthopade 20031201
Pharmacological prevention of breast cancer: quo vadis? Breast (Edinburgh, Scotland) 20031201
Compliance of osteoporotic patients with different treatment regimens. The Israel Medical Association journal : IMAJ 20031201
Effect of raloxifene on insulin-like growth factor-I, insulin-like growth factor binding protein-3, and leptin in premenopausal women at high risk for developing breast cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20031201
Characterization of a membrane-associated estrogen receptor in a rat hypothalamic cell line (D12). Endocrine 20031201
Glycosaminoglycan profile in bladder and urethra of castrated rats treated with estrogen, progestogen, and raloxifene. American journal of obstetrics and gynecology 20031201
An approach to postmenopausal osteoporosis treatment: a case study review. Journal of the American Academy of Nurse Practitioners 20031201
Transition to raloxifene with and without low-dose estrogen therapy in postmenopausal women: effects on serum lipids and fibrinogen - a pilot study. Climacteric : the journal of the International Menopause Society 20031201
Osteoporosis management in the new millennium. Primary care 20031201
Mechanisms of action of antiresorptive therapies of postmenopausal osteoporosis. Endocrine regulations 20031201
Hormone therapy after endometrial cancer. The journal of the British Menopause Society 20031201
Skeletal and nonskeletal effects of raloxifene. Current osteoporosis reports 20031201
Playing the old piano: another tune for endocrine therapy? Journal of the National Cancer Institute 20031105
Apoptotic action of 17beta-estradiol in raloxifene-resistant MCF-7 cells in vitro and in vivo. Journal of the National Cancer Institute 20031105
Differential effects of estradiol and raloxifene on collagen biosynthesis in cultured human skin fibroblasts. International journal of molecular medicine 20031101
2-methoxyestradiol strongly inhibits human uterine sarcomatous cell growth. Gynecologic oncology 20031101
The role of selective estrogen receptor modulators (SERMs) in postmenopausal health. Annals of the New York Academy of Sciences 20031101
Raloxifene inhibits estrogen-induced up-regulation of telomerase activity in a human breast cancer cell line. The Journal of biological chemistry 20031031
Effect of raloxifene on bone mineral density and biochemical markers of bone turnover in Japanese postmenopausal women with osteoporosis: results from a randomized placebo-controlled trial. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20031001
Osteoporosis: evaluation and treatment. Current women's health reports 20031001
Medical treatment of vertebral osteoporosis. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20031001
Effects of long-term administration of N-3 polyunsaturated fatty acids (PUFA) and selective estrogen receptor modulator (SERM) derivatives in ovariectomized (OVX) mice. Journal of cellular biochemistry 20031001
Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial. Bone 20031001
Nitrosation, nitration, and autoxidation of the selective estrogen receptor modulator raloxifene by nitric oxide, peroxynitrite, and reactive nitrogen/oxygen species. Chemical research in toxicology 20031001
Effects of raloxifene, hormone replacement therapy, and placebo on bone turnover in postmenopausal women. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20031001
A review of selective estrogen receptor modulators and national surgical adjuvant breast and bowel project clinical trials. Seminars in oncology 20031001
DT56a stimulates creatine kinase specific activity in vascular tissues of rats. Journal of endocrinological investigation 20031001
Effect of raloxifene combined with monofluorophosphate as compared with monofluorophosphate alone in postmenopausal women with low bone mass: a randomized, controlled trial. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20030901
Estrogen and raloxifene induce apoptosis by activating p38 mitogen-activated protein kinase cascade in synthetic vascular smooth muscle cells. The Journal of endocrinology 20030901
Contribution of raloxifene and calcium and vitamin D3 supplementation to the increase of the degree of mineralization of bone in postmenopausal women. The Journal of clinical endocrinology and metabolism 20030901
Raloxifene concurrently stimulates osteoprotegerin and inhibits interleukin-6 production by human trabecular osteoblasts. The Journal of clinical endocrinology and metabolism 20030901
Effect of raloxifene on the risk of new vertebral fracture in postmenopausal women with osteopenia or osteoporosis: a reanalysis of the Multiple Outcomes of Raloxifene Evaluation trial. Bone 20030901
Effect of raloxifene on sexual function in postmenopausal women. Climacteric : the journal of the International Menopause Society 20030901
Effects of raloxifene on endothelium-dependent dilation, lipoproteins, and markers of vascular function in postmenopausal women with coronary artery disease. Journal of the American College of Cardiology 20030820
Synthesis and binding affinities of fluoroalkylated raloxifenes. Bioorganic & medicinal chemistry 20030815
Early discontinuation of treatment for osteoporosis. The American journal of medicine 20030815
[Osteoporosis therapy compared. More solid bones with bisphosphonates]. MMW Fortschritte der Medizin 20030807
[Treatment of osteoporosis]. Orvosi hetilap 20030803
Raloxifene analog LY117018 enhances the regeneration of sciatic nerve in ovariectomized female mice. Brain research 20030801
Both estrogen and raloxifene cause G1 arrest of vascular smooth muscle cells. The Journal of endocrinology 20030801
Effects of raloxifene hydrochloride on bone mineral density, bone metabolism and serum lipids in postmenopausal women: a randomized clinical trial in Beijing. Chinese medical journal 20030801
Review on raloxifene: profile of a selective estrogen receptor modulator. International journal of clinical pharmacology and therapeutics 20030801
Synthesis of constrained raloxifene analogues by complementary use of Friedel-Crafts and directed remote metalation reactions. The Journal of organic chemistry 20030725
Breast-cancer prevention: is the risk-benefit ratio in favour of tamoxifen? Lancet (London, England) 20030719
Mutation of Leu-536 in human estrogen receptor-alpha alters the coupling between ligand binding, transcription activation, and receptor conformation. The Journal of biological chemistry 20030718
[Evidence-based assessment of therapeutic agents of osteoporosis. Bisphosphonates, SERM and basic therapy in front]. MMW Fortschritte der Medizin 20030710
Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands. Journal of medicinal chemistry 20030703
Oestrogen replacement therapy lowers plasma levels of asymmetrical dimethylarginine in healthy postmenopausal women. Clinical science (London, England : 1979) 20030701
Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Molecular endocrinology (Baltimore, Md.) 20030701
New approaches to the endocrine prevention and treatment of breast cancer. Cancer chemotherapy and pharmacology 20030701
Raloxifene, conjugated oestrogen and endothelial function in postmenopausal women. Journal of internal medicine 20030701
Efficacy and safety of raloxifene 60 milligrams/day in postmenopausal Asian women. The Journal of clinical endocrinology and metabolism 20030701
Differential effects of unopposed versus opposed hormone therapy, tibolone, and raloxifene on substance p levels. Fertility and sterility 20030701
The prevention of breast cancer. The British journal of surgery 20030701
Short-term urogenital effects of raloxifene, tamoxifen, and estrogen. American journal of obstetrics and gynecology 20030701
DT56a (Tofupill/Femarelle) selectively stimulates creatine kinase specific activity in skeletal tissues of rats but not in the uterus. The Journal of steroid biochemistry and molecular biology 20030701
The effects of raloxifene and simvastatin on plasma lipids and endothelium. Cardiovascular drugs and therapy 20030701
Osteoporosis guidelines. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030624
Osteoporosis guidelines. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030624
[From alcohol abstinence to total surgery. Preventive strategies in breast carcinoma]. MMW Fortschritte der Medizin 20030612
[Hormone therapy, chemotherapy and immunotherapy in breast carcinoma. The best strategy for your patient]. MMW Fortschritte der Medizin 20030612
Raloxifene causing malabsorption of levothyroxine. Archives of internal medicine 20030609
A novel estrogen receptor ligand template. Bioorganic & medicinal chemistry letters 20030602
Effects of raloxifene on bone metabolism and serum lipids in postmenopausal women on chronic hemodialysis. Kidney international 20030601
Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors alpha and beta. Journal of cellular biochemistry 20030601
Interleukin-6 (IL-6), IL-1, receptor activator of nuclear factor kappaB ligand (RANKL) and osteoprotegerin production by human osteoblastic cells: comparison of the effects of 17-beta oestradiol and raloxifene. The Journal of endocrinology 20030601
Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. The Journal of clinical investigation 20030601
Effect of raloxifene, 17beta-estradiol, and progesterone on mRNA for vascular endothelial growth factor isoforms 121 and 165 and thrombospondin-1 in Ishikawa cells. Fertility and sterility 20030601
Effects of raloxifene therapy on the anticoagulant system in postmenopausal women. Climacteric : the journal of the International Menopause Society 20030601
Associated response in bone mineral density and atherogenic lipid profile during treatment with two different selective estrogen receptor modulators: levormeloxifene and raloxifene. Climacteric : the journal of the International Menopause Society 20030601
Risk of fracture and treatment to prevent osteoporosis-related fracture in postmenopausal women. A review. The Journal of reproductive medicine 20030601
Serum lipids and apolipoproteins in Greek postmenopausal women: association with estrogen, estrogen-progestin, tibolone and raloxifene therapy. Journal of endocrinological investigation 20030601
Effects of SP500263, a novel selective estrogen receptor modulator, on bone, uterus, and serum cholesterol in the ovariectomized rat. Calcified tissue international 20030601
Effects of estradiol, cyproterone acetate, tibolone and raloxifene on uterus and aorta atherosclerosis in oophorectomized cholesterol-fed rabbits. Maturitas 20030530
[SERM for early osteoporosis therapy. Risk for first spinal fracture reduced to half]. MMW Fortschritte der Medizin 20030529
New bone formation with teriparatide [human parathyroid hormone-(1-34)] is not retarded by long-term pretreatment with alendronate, estrogen, or raloxifene in ovariectomized rats. Endocrinology 20030501
Endothelial function and menopause: effects of raloxifene administration. The Journal of clinical endocrinology and metabolism 20030501
Administration of raloxifene does not influence 24-hour ambulatory blood pressure of postmenopausal women with osteopenia: a double-blind placebo-controlled study. American journal of obstetrics and gynecology 20030501
Differential effects of raloxifene and estrogen on insulin sensitivity in postmenopausal women. Journal of the American Geriatrics Society 20030501
Chemoprevention of breast cancer: recommendations and rationale. The American journal of nursing 20030501
Differential effects of raloxifene, tamoxifen and fulvestrant on a murine mammary carcinoma. Breast cancer research and treatment 20030501
Long-term toxicities of selective estrogen-receptor modulators and antiaromatase agents. Oncology (Williston Park, N.Y.) 20030501
The effects of estrogen and raloxifene treatment on antioxidant enzymes in brain and liver of ovarectomized female rats. Endocrine research 20030501
Selective estrogen-receptor modulators. Clinics in geriatric medicine 20030501
Drugs in the news: an analysis of Canadian newspaper coverage of new prescription drugs. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030429
Estrogen alone or combined with medroxyprogesterone but not raloxifene reduce myocardial infarct size. European journal of pharmacology 20030425
[Rehabilitation in osteoporosis]. Deutsche medizinische Wochenschrift (1946) 20030425
Effect of chronic estradiol, tamoxifen or raloxifene treatment on serotonin 5-HT1A receptor. Brain research. Molecular brain research 20030410
[Untrustworthy criticism of an advertising brochure]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030410
De novo design, synthesis and evaluation of a non-steroidal diphenylnaphthyl propylene ligand for the estrogen receptor. Bioorganic & medicinal chemistry 20030403
Raloxifene acts as an estrogen agonist on the rabbit growth plate. Endocrinology 20030401
Raloxifene lowers IGF-I levels in acromegalic women. European journal of endocrinology 20030401
Experts hopeful about designer estrogens. For some women, selective estrogen receptor modulators (SERMs) help prevent breast cancer. Health news (Waltham, Mass.) 20030401
Adrenal function under long-term raloxifene administration. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030401
Repeated estradiol treatment prevents MPTP-induced dopamine depletion in male mice. Neuroendocrinology 20030401
[A randomised clinical trial to study the effects of raloxifene hydrochloride on bone mineral density, biochemical markers of bone metabolism and serum lipids in postmenopausal women]. Zhonghua fu chan ke za zhi 20030401
[Breakthrough in breast cancer chemoprevention]. Orvosi hetilap 20030330
Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents. Journal of medicinal chemistry 20030327
Chemoprevention of breast cancer: recommendations and rationale. American family physician 20030315
The effects of estrogen and raloxifene treatment on the antioxidant enzymes and nitrite-nitrate levels in brain cortex of ovariectomized rats. Neuroscience letters 20030306
A homogeneous in vitro functional assay for estrogen receptors: coactivator recruitment. Molecular endocrinology (Baltimore, Md.) 20030301
Effects of raloxifene on carotid blood flow resistance and endothelium-dependent vasodilation in postmenopausal women. Atherosclerosis 20030301
Anti-oestrogenic chemoprevention of breast cancer-the need to progress. European journal of cancer (Oxford, England : 1990) 20030301
Raloxifene lowers serum calcium and markers of bone turnover in postmenopausal women with primary hyperparathyroidism. The Journal of clinical endocrinology and metabolism 20030301
Selective estrogen receptors modulators in the prevention and treatment of postmenopausal osteoporosis. Endocrinology and metabolism clinics of North America 20030301
[SERMs and uterus]. Annales de medecine interne 20030301
Post hoc analysis of data from the Multiple Outcomes of Raloxifene Evaluation (MORE) trial on the effects of three years of raloxifene treatment on glycemic control and cardiovascular disease risk factors in women with and without type 2 diabetes. Clinical therapeutics 20030301
Differential SERM effects on corepressor binding dictate ERalpha activity in vivo. The Journal of biological chemistry 20030227
[Diabetes, Conn syndrome and osteoporosis. What is new in diagnosis and therapy?]. MMW Fortschritte der Medizin 20030227
Application of breast cancer risk prediction models in clinical practice. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030215
Selective estrogen-receptor modulators -- mechanisms of action and application to clinical practice. The New England journal of medicine 20030213
2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs). Bioorganic & medicinal chemistry letters 20030210
Effect of raloxifene, estrogen, and hormone replacement therapy on serum homocysteine levels in postmenopausal women. Fertility and sterility 20030201
Effect of raloxifene on the response to conjugated estrogen vaginal cream or nonhormonal moisturizers in postmenopausal vaginal atrophy. Obstetrics and gynecology 20030201
Effect of raloxifene on sexual function in older postmenopausal women with osteoporosis. Obstetrics and gynecology 20030201
Comparison of the effect of oestradiol, tamoxifen and raloxifene on nerve growth factor-alpha expression in specific neonatal mouse uterine cell types using laser capture microdissection. Journal of molecular endocrinology 20030201
Raloxifene and endothelial function in healthy postmenopausal women. American journal of obstetrics and gynecology 20030201
Raloxifene does not influence flow-mediated endothelium-dependent and endothelium-independent vasodilatation of osteopenic postmenopausal women. American journal of obstetrics and gynecology 20030201
Comparison of the effect of raloxifene and continuous-combined hormone therapy on mammographic breast density and breast tenderness in postmenopausal women. American journal of obstetrics and gynecology 20030201
[The therapy of endometriosis. New prospects]. Minerva ginecologica 20030201
A multicentre randomised trial to compare uterine safety of raloxifene with a continuous combined hormone replacement therapy containing oestradiol and norethisterone acetate. BJOG : an international journal of obstetrics and gynaecology 20030201
[Cardiovascular effects of selective estrogen receptor modulators. Current perspectives]. Recenti progressi in medicina 20030201
Overview of the main outcomes in breast-cancer prevention trials. Lancet (London, England) 20030125
[Absolutely not true and relatively true about risk reduction]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030109
The hidden alternative: getting investigational treatments off-study. Lancet (London, England) 20030104
Nongenomic activity and subsequent c-fos induction by estrogen receptor ligands are not sufficient to promote deoxyribonucleic acid synthesis in human endometrial adenocarcinoma cells. Endocrinology 20030101
Biological significance of interventions that change breast density. Journal of the National Cancer Institute 20030101
Growth effects of raloxifene, estradiol, medroxy-progesterone acetate, and progesterone on human endometrial adenocarcinoma cells. Fertility and sterility 20030101
Raloxifene administration in post-menopausal women with osteoporosis: effect of different BsmI vitamin D receptor genotypes. Human reproduction (Oxford, England) 20030101
National surgical adjuvant breast and bowel project update: prevention trials and endocrine therapy of ductal carcinoma in situ. Clinical cancer research : an official journal of the American Association for Cancer Research 20030101
Influence of raloxifene on the efficacy of an estradiol-releasing ring for treating vaginal atrophy in postmenopausal women. Menopause (New York, N.Y.) 20030101
[The current state of hormonal prevention of coronary heart disease in menopausal women]. Revista espanola de cardiologia 20030101
Raloxifene to prevent cardiovascular disease? Don't use it yet! Menopause (New York, N.Y.) 20030101
Raloxifene is a better antioxidant of low-density lipoprotein than estradiol or tamoxifen in postmenopausal women in vitro. Menopause (New York, N.Y.) 20030101
Effects of bilateral ovariectomy and postoperative hormonal replacement therapy with 17beta-estradiol or raloxifene on serum leptin levels. Menopause (New York, N.Y.) 20030101
Lack of hormonal influences on mechanical properties of sheep knee ligaments. The American journal of sports medicine 20030101
Prevention and early detection clinical trials: opportunities for primary care providers and their patients. CA: a cancer journal for clinicians 20030101
Gender, hyperlipidemia, and coronary artery disease. Comprehensive therapy 20030101
Effects of SERM (selective estrogen receptor modulator) treatment on growth and proliferation in the rat uterus. Reproductive biology and endocrinology : RB&E 20030101
Counseling patients who elect to discontinue hormone therapy. International journal of fertility and women's medicine 20030101
Therapeutic options: an evidence-based approach to prevention and treatment of osteoporosis. International journal of fertility and women's medicine 20030101
Treatment of osteoporosis: combination therapies. International journal of fertility and women's medicine 20030101
Direct-to-consumer marketing of osteoporosis drugs and bone densitometry. The Annals of pharmacotherapy 20030101
Prevention of osteoporosis and uterine effects in postmenopausal women taking raloxifene for 5 years. Menopause (New York, N.Y.) 20030101
Conformational sampling by self-organization. Journal of chemical information and computer sciences 20030101
Growth response of colon cancer cell lines to selective estrogen receptor modulators. Anticancer research 20030101
[Perspectives for the hormonal therapy of breast cancer]. Magyar onkologia 20030101
Effect of raloxifene and clodronate on bone density in postmenopausal osteoporotic women. International journal of tissue reactions 20030101
Effects of estrogen and raloxifene on neuroglia number and morphology in the hippocampus of aged female mice. Neuroscience 20030101
beta-estradiol influences differentiation of hippocampal neurons in vitro through an estrogen receptor-mediated process. Neuroscience 20030101
Effects of an isopropanolic extract of Cimicifuga racemosa on urinary crosslinks and other parameters of bone quality in an ovariectomized rat model of osteoporosis. Journal of bone and mineral metabolism 20030101
Prevention of breast cancer using SERMs and aromatase inhibitors. Journal of mammary gland biology and neoplasia 20030101
Diagnosing and managing post menopausal osteoporosis: opportunities for fracture prevention. Comprehensive therapy 20030101
Treatment of desmoids and mesenteric fibromatosis in familial adenomatous polyposis with raloxifene. Tumori 20030101
Case report: raloxifene in postmenopausal women with psychosis: preliminary findings. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20030101
Modeling the annual costs of postmenopausal prevention therapy: raloxifene, alendronate, or estrogen-progestin therapy. Journal of managed care pharmacy : JMCP 20030101
ERT, HRT, raloxifine, calcitonin, or bisphosphonates for osteoporosis. Journal of managed care pharmacy : JMCP 20030101
Influence of tacrolimus and short-duration prednisone on bone mineral density following liver transplantation. JPEN. Journal of parenteral and enteral nutrition 20030101
[Treatment of postmenopausal osteoporosis]. Anales del sistema sanitario de Navarra 20030101
[Drugs prescription for osteoporosis]. Anales del sistema sanitario de Navarra 20030101
[The role of raloxifene (Evista) in the treatment and prevention of postmenopausal osteoporosis]. Reumatizam 20030101
Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment. Advances in experimental medicine and biology 20030101
Effect of raloxifene on lowering lipid parameters in patients with osteoporosis. International journal of clinical pharmacology research 20030101
Risk-reducing strategies for breast cancer--a review of recent literature. International journal of fertility and women's medicine 20030101
Hip fracture patients are not treated for osteoporosis: a call to action. Arthritis and rheumatism 20021215
Baseline characteristics of participants in the Raloxifene Use for The Heart (RUTH) trial. The American journal of cardiology 20021201
Effectiveness of combined GnRH analogue plus raloxifene administration in the treatment of uterine leiomyomas: a prospective, randomized, single-blind, placebo-controlled clinical trial. Human reproduction (Oxford, England) 20021201
Raloxifene, estrogen, and alendronate affect the processes of fracture repair differently in ovariectomized rats. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021201
Medications for postmenopausal osteoporosis prevention. Harvard women's health watch 20021201
Differential effects of selective estrogen receptor modulators and estrogens on mammary blood flow in the ovine. American journal of obstetrics and gynecology 20021201
ACOG practice bulletin. Selective estrogen receptor modulators. Number 39, October 2002 (replaces Committee Opinion Number 224, October 1999). International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20021201
[Effects of the combined raloxifene-sodium fluoride therapy on bone mass and bone turnover in women with postmenopausal osteoporosis]. Minerva medica 20021201
[Osteoporosis]. Der Internist 20021201
[Osteoporosis]. Ryumachi. [Rheumatism] 20021201
Rapid effects of estrogen on G protein-coupled receptor activation of potassium channels in the central nervous system (CNS). The Journal of steroid biochemistry and molecular biology 20021201
Antiestrogens: the past and the future. Zentralblatt fur Gynakologie 20021201
[Treatments of Osteoporosis with SERM and their EBM]. Clinical calcium 20021201
[Rationale for the treatment of postmenopausal women by SERM]. Clinical calcium 20021201
[Osteoporosis: prevention of bone loss and fractures]. MMW Fortschritte der Medizin 20021128
Estrogen receptor-dependent and estrogen receptor-independent pathways for tamoxifen and 4-hydroxytamoxifen-induced programmed cell death. The Journal of biological chemistry 20021122
Tamoxifen versus raloxifene in the prevention of breast cancer. European journal of cancer (Oxford, England : 1990) 20021101
An update on non-uterine gynaecological effects on raloxifene. European journal of cancer (Oxford, England : 1990) 20021101
The role of estrogens and related compounds in the management of primary hyperparathyroidism. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021101
Effects of raloxifene on fracture severity in postmenopausal women with osteoporosis: results from the MORE study. Multiple Outcomes of Raloxifene Evaluation. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20021101
Bioidentical hormone replacement therapy. Customizing care for perimenopausal and menopausal women. Advance for nurse practitioners 20021101
Drugs for prevention and treatment of postmenopausal osteoporosis. Treatment guidelines from the Medical Letter 20021101
[Weeks of pain, vertebral body fractures during sleep, invalidism. Save your osteoporosis patients from this fate]. MMW Fortschritte der Medizin 20021031
Solid-phase synthesis and investigation of benzofurans as selective estrogen receptor modulators. Bioorganic & medicinal chemistry letters 20021021
[Do markers of bone metabolism reflect the presence of a high- or low-turnover state of bone metabolism?]. Medizinische Klinik (Munich, Germany : 1983) 20021015
Pharmacological actions of a novel, potent, tissue-selective benzopyran estrogen. The Journal of pharmacology and experimental therapeutics 20021001
Selective estrogen receptor (ER) modulators differentially regulate phospholipase D catalytic activity in ER-negative breast cancer cells. Molecular pharmacology 20021001
Raloxifene administration in women treated with gonadotropin-releasing hormone agonist for uterine leiomyomas: effects on bone metabolism. The Journal of clinical endocrinology and metabolism 20021001
Effects of long-lasting raloxifene treatment on serum prolactin and gonadotropin levels in postmenopausal women. European journal of endocrinology 20021001
Responsiveness of endometrial genes Connexin26, Connexin43, C3 and clusterin to primary estrogen, selective estrogen receptor modulators, phyto- and xenoestrogens. Journal of molecular endocrinology 20021001
Endometriosis: novel etiopathogenetic concepts and clinical perspectives. Fertility and sterility 20021001
ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists: Number 39, October 2002. Selective estrogen receptor modulators. Obstetrics and gynecology 20021001
Task force cautious about chemoprevention. Official guidelines are out about taking tamoxifen and raloxifene to prevent breast cancer. These drugs can help, but they aren't for everyone. Harvard women's health watch 20021001
Estrogenic properties of raloxifene, but not tamoxifen, on D2 and D3 dopamine receptors in the rat forebrain. Neuroendocrinology 20021001
Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis in androgen-independent human prostate cancer cell lines. Cancer research 20020915
[Specific estrogen receptor modulators (SERMs)]. Presse medicale (Paris, France : 1983) 20020907
Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis through cleavage of BAD in TSU-PR1 human cancer cells. The Journal of biological chemistry 20020906
Raloxifene effects upon the neuronal system controlling sexual receptivity in female rats. Neuroscience letters 20020906
Amelioration of ischemia- and reperfusion-induced myocardial injury by the selective estrogen receptor modulator, raloxifene, in the canine heart. Journal of the American College of Cardiology 20020904
Raloxifene does not modify insulin sensitivity and glucose metabolism in postmenopausal women. The Journal of clinical endocrinology and metabolism 20020901
The effect of raloxifene on glyco-insulinemic homeostasis in healthy postmenopausal women: a randomized placebo-controlled study. The Journal of clinical endocrinology and metabolism 20020901
Effects of oral raloxifene on serum estradiol levels and other markers of estrogenicity. Fertility and sterility 20020901
Osteoporosis. Postgraduate medical journal 20020901
Breast cancer prevention and surveillance. Clinical obstetrics and gynecology 20020901
The Study of Tamoxifen and Raloxifene (STAR trial) for the prevention of breast cancer. Hawaii medical journal 20020901
American Society of Clinical Oncology technology assessment of pharmacologic interventions for breast cancer risk reduction including tamoxifen, raloxifene, and aromatase inhibition. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020801
Gene expression profiles with activation of the estrogen receptor alpha-selective estrogen receptor modulator complex in breast cancer cells expressing wild-type estrogen receptor. Cancer research 20020801
Raloxifene administration in premenopausal women with uterine leiomyomas: a pilot study. The Journal of clinical endocrinology and metabolism 20020801
Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis: four-year results from a randomized clinical trial. The Journal of clinical endocrinology and metabolism 20020801
Improvement in the undertreatment of osteoporosis following hip fracture. The Journal of bone and joint surgery. American volume 20020801
A randomised, double-blind trial comparing raloxifene HCl and continuous combined hormone replacement therapy in postmenopausal women: effects on compliance and quality of life. BJOG : an international journal of obstetrics and gynaecology 20020801
Meta-analyses of therapies for postmenopausal osteoporosis. IV. Meta-analysis of raloxifene for the prevention and treatment of postmenopausal osteoporosis. Endocrine reviews 20020801
Estrogen and selective estrogen receptor modulator regulation of insulin-like growth factor binding protein 5 in the rat uterus. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20020801
Tamoxifen and raloxifene may benefit women at high risk for breast cancer. Report on medical guidelines & outcomes research 20020726
[CBO guideline 'Osteoporosis' (second revision]. Nederlands tijdschrift voor geneeskunde 20020720
USPSTF releases guidelines on breast-cancer chemoprevention. Lancet (London, England) 20020706
Raloxifene and risk of cardiovascular events. JAMA 20020703
Chemoprevention of breast cancer: recommendations and rationale. Annals of internal medicine 20020702
Chemoprevention of breast cancer: a summary of the evidence for the U.S. Preventive Services Task Force. Annals of internal medicine 20020702
Summaries for patients. Using medication to prevent breast cancer: recommendations from the United States Preventive Services Task Force. Annals of internal medicine 20020702
Estrogen receptor alpha inhibits IL-1beta induction of gene expression in the mouse liver. Endocrinology 20020701
Raloxifene, a selective estrogen receptor modulator, induces apoptosis in androgen-responsive human prostate cancer cell line LNCaP through an androgen-independent pathway. Cancer research 20020701
Raloxifene: recent information on skeletal and non-skeletal effects. Current opinion in rheumatology 20020701
Cytochrome P450 3A4-mediated bioactivation of raloxifene: irreversible enzyme inhibition and thiol adduct formation. Chemical research in toxicology 20020701
[What can we expect of raloxifene in the treatment of postmenopausal osteoporosis--views of a gynecologist]. Ceska gynekologie 20020701
Differential interactions of estrogens and antiestrogens at the 17 beta-hydroxyl or counterpart hydroxyl with histidine 524 of the human estrogen receptor alpha. Biochemistry 20020625
Tamoxifen, raloxifene and the prevention of breast cancer. Minerva endocrinologica 20020601
Characterization of raloxifene glucuronidation in vitro: contribution of intestinal metabolism to presystemic clearance. Drug metabolism and disposition: the biological fate of chemicals 20020601
The search for the ideal SERM. Expert opinion on pharmacotherapy 20020601
Review of raloxifene and its clinical applications in osteoporosis. Expert opinion on pharmacotherapy 20020601
Raloxifene and cardiovascular disease. Climacteric : the journal of the International Menopause Society 20020601
Transvaginal color Doppler sonographic evaluation of the uterus in postmenopausal women on daily raloxifene therapy. Climacteric : the journal of the International Menopause Society 20020601
Regulation of estrogen target genes and growth by selective estrogen-receptor modulators in endometrial cancer cells. Gynecologic oncology 20020601
Raloxifene treatment increases plasma levels of beta-endorphin in postmenopausal women: a randomized, placebo-controlled study. Fertility and sterility 20020601
Effects of a new clinically relevant antiestrogen (GW5638) related to tamoxifen on breast and endometrial cancer growth in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research 20020601
[Antiestrogen therapy in the treatment of breast neoplasms]. Minerva ginecologica 20020601
6-Carboxymethyl genistein: a novel selective oestrogen receptor modulator (SERM) with unique, differential effects on the vasculature, bone and uterus. The Journal of endocrinology 20020601
Use of alternative therapies in menopause. Best practice & research. Clinical obstetrics & gynaecology 20020601
Breast pain and mammographic density increase as a consequence of raloxifene therapy. Journal of endocrinological investigation 20020601
The study of tamoxifen and raloxifene: preliminary enrollment data from a randomized breast cancer risk reduction trial. Clinical breast cancer 20020601
A review of selective estrogen receptor modulators in the treatment of breast and endometrial cancer. Seminars in oncology 20020601
The effects of estrogen replacement therapy on neuropsychological functioning in postmenopausal women with and without dementia: a critical and theoretical review. Neuropsychology review 20020601
Early effects of raloxifene on clinical vertebral fractures at 12 months in postmenopausal women with osteoporosis. Archives of internal medicine 20020527
[From effective to economical. The value of good osteoporosis therapy]. MMW Fortschritte der Medizin 20020523
Mood effect of raloxifene in postmenopausal women. Maturitas 20020520
Transvaginal sonographic monitoring of the uterine effects of raloxifene and a continuous combined replacement therapy in postmenopausal women. Maturitas 20020520
Comparison of the effects of EM-652 (SCH57068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast tumors in nude mice. International journal of cancer 20020510
[Can serum estradiol predict the effect of raloxifene on breast cancer risk?]. Lakartidningen 20020502
Effects of oral estrogen, raloxifene and arzoxifene on gene expression in serotonin neurons of macaques. Psychoneuroendocrinology 20020501
The effect of raloxifene on the incidence of ovarian cancer in postmenopausal women. Gynecologic oncology 20020501
Mechanism of raloxifene-induced relaxation in femoral veins depends on ovarian hormonal status. Journal of cardiovascular pharmacology 20020501
Effect of raloxifene on the ovarian circulation in women after menopause. American journal of obstetrics and gynecology 20020501
Effects of hormones on uPA, PAI-1 and suPAR from cultured endometrial and ovarian endometriotic stromal cells. Acta obstetricia et gynecologica Scandinavica 20020501
Menopause. HRT: looking for something better. Harvard health letter 20020501
Cardiovascular effects of raloxifene: the potential for cardiovascular protection in women. Diabetes, obesity & metabolism 20020501
Pharmacotherapy of osteoporosis in postmenopausal women: focus on safety. Expert opinion on drug safety 20020501
Raloxifene improves endothelial dysfunction in hypertension by reduced oxidative stress and enhanced nitric oxide production. Circulation 20020430
Growth-stimulatory and transcriptional activation properties of raloxifene in human endometrial Ishikawa cells. Molecular and cellular endocrinology 20020425
A 60-year-old woman trying to discontinue hormone replacement therapy. JAMA 20020424
[Current therapeutic means]. Presse medicale (Paris, France : 1983) 20020420
Upstaging tamoxifen? New classes of drugs emerging for breast cancer. Journal of the National Cancer Institute 20020403
Effect of 1 year of discontinuation of raloxifene or estrogen therapy on bone mineral density after 5 years of treatment in healthy postmenopausal women. Bone 20020401
Identifying and counseling women at increased risk for breast cancer. Mayo Clinic proceedings 20020401
Environmental fate and chemistry of raloxifene hydrochloride. Environmental toxicology and chemistry 20020401
Neither long-term treatment with raloxifene nor hormone replacement therapy modulate cardiac function in healthy postmenopausal women: two randomized, placebo-controlled, 2-year studies. American journal of obstetrics and gynecology 20020401
Effects of the selective estrogen receptor modulator, raloxifene, on carotid artery pulsatility index in postmenopausal women. American journal of obstetrics and gynecology 20020401
Raloxifene is associated with less side effects than tamoxifen in women with early breast cancer: a questionnaire study from one physician's practice. Journal of women's health & gender-based medicine 20020401
Efficacy of raloxifene for treatment of menopause: a systematic review. Journal of the American Academy of Nurse Practitioners 20020401
Raloxifene remains an option. Canadian family physician Medecin de famille canadien 20020401
[Rational and cost effective osteoporosis prevention and therapy]. Der Internist 20020401
The controversy over estrogen replacement therapy: an update on clinical trials. Current women's health reports 20020401
Biomedicine. Defining the 'S' in SERMs. Science (New York, N.Y.) 20020329
Molecular determinants for the tissue specificity of SERMs. Science (New York, N.Y.) 20020329
Measurement of serum estradiol. JAMA 20020327
Nongenomic mechanisms of endothelial nitric oxide synthase activation by the selective estrogen receptor modulator raloxifene. Circulation 20020319
Structure-function relationships of the raloxifene-estrogen receptor-alpha complex for regulating transforming growth factor-alpha expression in breast cancer cells. The Journal of biological chemistry 20020315
Hormone replacement therapy trials: an update. Current atherosclerosis reports 20020301
A synthetic peptide with estrogen-like activity derived from a phage-display peptide library. Peptides 20020301
Raloxifene revisited. Fertility and sterility 20020301
Estradiol down-regulates MCP-1 expression in human coronary artery endothelial cells. Fertility and sterility 20020301
Comparative effects of testosterone propionate, oestradiol benzoate, ICI 182,780, tamoxifen and raloxifene on hypothalamic differentiation in the female rat. The Journal of endocrinology 20020301
Inhibition of intimal hyperplasia using the selective estrogen receptor modulator raloxifene. Archives of surgery (Chicago, Ill. : 1960) 20020301
For osteoporosis, are two antiresorptive drugs better than one? The Journal of clinical endocrinology and metabolism 20020301
Additive effects of raloxifene and alendronate on bone density and biochemical markers of bone remodeling in postmenopausal women with osteoporosis. The Journal of clinical endocrinology and metabolism 20020301
Hormone may be key to raloxifene's breast cancer benefits. Health news (Waltham, Mass.) 20020301
Molecular simulation of interaction between estrogen receptor and selective estrogen receptor modulators. Acta pharmacologica Sinica 20020301
Therapeutic interventions in osteoporosis. Nursing times 20020301
[Advancement of treatment for osteoporosis]. Nihon rinsho. Japanese journal of clinical medicine 20020301
[Treatment of osteoporosis: overview]. Nihon rinsho. Japanese journal of clinical medicine 20020301
[Comparative analyses on osteoporosis guidelines in Japan, EU and USA]. Nihon rinsho. Japanese journal of clinical medicine 20020301
[Advance in the treatment of postmenopausal osteoporosis]. Nihon rinsho. Japanese journal of clinical medicine 20020301
[Drugs in development for the treatment of osteoporosis:Raloxifene]. Nihon rinsho. Japanese journal of clinical medicine 20020301
[Hormone replacement therapy in peri- and postmenopause. Routine use is not indicated]. MMW Fortschritte der Medizin 20020227
A 2-year, randomized, comparative, placebo-controlled study on the effects of raloxifene on lipoprotein(a) and homocysteine. Maturitas 20020226
Raloxifene and cardiovascular events in osteoporotic postmenopausal women: four-year results from the MORE (Multiple Outcomes of Raloxifene Evaluation) randomized trial. JAMA 20020220
Hobson's choice and the need for combinations of new agents for the prevention and treatment of breast cancer. Journal of the National Cancer Institute 20020220
Effects of raloxifene after tamoxifen on breast and endometrial tumor growth in athymic mice. Journal of the National Cancer Institute 20020220
Estrogen replacement therapy, atherosclerosis, and vascular function. Cardiovascular research 20020215
Role of antiestrogens and aromatase inhibitors in breast cancer treatment. Current opinion in obstetrics & gynecology 20020201
Current status and future innovations of hormonal agents, chemotherapy and investigational agents in endometrial cancer. Current opinion in obstetrics & gynecology 20020201
Bone histomorphometric and biochemical marker results of a 2-year placebo-controlled trial of raloxifene in postmenopausal women. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020201
Selective estrogen receptor modulators (SERMS) and their roles in breast cancer prevention. Trends in molecular medicine 20020201
The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro. Bone 20020201
Effects of estrogen-progestin and raloxifene therapy on nitric oxide, prostacyclin and endothelin-1 synthesis. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20020201
Recruitment of women into trials. Lancet (London, England) 20020112
Raloxifene enhances nitric oxide release in rat aorta via increasing endothelial nitric oxide mRNA expression. European journal of pharmacology 20020111
Serum estradiol level and risk of breast cancer during treatment with raloxifene. JAMA 20020109
Teasing out effects of estrogen on the brain. JAMA 20020102
Relationships between bone mineral density and incident vertebral fracture risk with raloxifene therapy. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020101
Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020101
Raloxifene does not affect insulin sensitivity or glycemic control in postmenopausal women with type 2 diabetes mellitus: a randomized clinical trial. The Journal of clinical endocrinology and metabolism 20020101
Recovery of proximal tibia bone mineral density and strength, but not cancellous bone architecture, after long-term bisphosphonate or selective estrogen receptor modulator therapy in aged rats. Bone 20020101
Selective estrogen receptor modulator effects in the rat brain. Neuroendocrinology 20020101
Breast cancer risk reduction: strategies for women at increased risk. Annual review of medicine 20020101
[Amelioration of ischemia- and reperfusion-induced myocardial injury by the selective estrogen receptor modulator, raloxifene, in the canine heart]. Journal of cardiology 20020101
Breast cancer prevention. The oncologist 20020101
Effects of the environmental estrogens bisphenol A, o,p'-DDT, p-tert-octylphenol and coumestrol on apoptosis induction, cell proliferation and the expression of estrogen sensitive molecular parameters in the human breast cancer cell line MCF-7. The Journal of steroid biochemistry and molecular biology 20020101
Hormone replacement therapy and breast tissue density on mammography. Menopause (New York, N.Y.) 20020101
Mammographic changes associated with raloxifene and tibolone therapy in postmenopausal women: a prospective study. Menopause (New York, N.Y.) 20020101
Toxicity of antiestrogens. The breast journal 20020101
Selective estrogen receptor modulators as a new therapeutic drug group: concept to reality in a decade. Clinical breast cancer 20020101
Selective estrogen receptor modulators (SERMs) and retinoids in breast cancer chemoprevention. Environmental and molecular mutagenesis 20020101
Chemoprevention of breast cancer: implications for postmenopausal women. Drugs & aging 20020101
Estradiol and raloxifene decrease the formation of multinucleate cells in human bone marrow cultures. European cytokine network 20020101
Estradiol, but not raloxifene, improves aspects of spatial working memory in aged ovariectomized rhesus monkeys. Neurobiology of aging 20020101
Sequence- and time-dependent antagonism between raloxifene and methotrexate in human breast cancer cells. Anticancer research 20020101
Response of bone mineral density to once-weekly administration of risedronate. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101
The hemorheological effects of raloxifene in postmenopausal women with osteoporosis. Results of a 3-year placebo-controlled clinical trial. Clinical hemorheology and microcirculation 20020101
Serum placental protein 14: a novel marker of selective oestrogen receptor modulator action on the postmenopausal endometrium. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20020101
Development of cross-resistance to tamoxifen in raloxifene-treated breast carcinoma cells. Anticancer research 20020101
Similarity of uterine mucosa changes in patients treated by raloxifen and tamoxifen. Anticancer research 20020101
[Selective estrogen receptor modulators (SERMs) in the practice]. Magyar onkologia 20020101
How does raloxifene reduce fracture risk? Menopause (New York, N.Y.) 20020101
Effects of raloxifene on bone density, biomarkers, and histomorphometric and biomechanical measures in ovariectomized cynomolgus monkeys. Menopause (New York, N.Y.) 20020101
Selective estrogen receptor modulators: tissue actions and potential for CNS protection. CNS drug reviews 20020101
Jumping exercises with and without raloxifene treatment in healthy elderly women. Journal of bone and mineral metabolism 20020101
Effects of estrogens and selective estrogen receptor modulators on indicators of cardiovascular health in postmenopausal women. Medscape women's health 20020101
A review of combination regimens for osteoporosis--prevention and treatment. International journal of fertility and women's medicine 20020101
[Osteoporosis: diagnosis, prevention and treatment]. Medicina (Kaunas, Lithuania) 20020101
Vascular effects of raloxifene in post-menopausal women. Journal of endocrinological investigation 20020101
Raloxifene and pituitary secretion in post-menopausal women. Journal of endocrinological investigation 20020101
Chemoprevention of breast cancer: current and future prospects. Cancer metastasis reviews 20020101
[Osteoporosis]. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20020101
Activity of a tamoxifen-raloxifene hybrid ligand for estrogen receptors at an AP-1 site. Bioorganic & medicinal chemistry letters 20011217
Induction of endothelial nitric-oxide synthase phosphorylation by the raloxifene analog LY117018 is differentially mediated by Akt and extracellular signal-regulated protein kinase in vascular endothelial cells. The Journal of biological chemistry 20011214
Raloxifene. Current drug targets 20011201
Effect of raloxifene on IGF-I and IGFBP-3 in postmenopausal women with breast cancer. British journal of cancer 20011201
Cost-effectiveness of raloxifene and hormone replacement therapy in postmenopausal women: impact of breast cancer risk. Obstetrics and gynecology 20011201
Spontaneous reports of pulmonary embolism in association with raloxifene. Obstetrics and gynecology 20011201
Effect of hormone replacement therapies and selective estrogen receptor modulators in postmenopausal women with uterine leiomyomas: a literature review. Climacteric : the journal of the International Menopause Society 20011201
Differential effects of raloxifene and continuous combined hormone replacement therapy on biochemical markers of cardiovascular risk: results from the Euralox 1 study. Climacteric : the journal of the International Menopause Society 20011201
Effects of phytoestrogens on DNA synthesis and creatine kinase activity in vascular cells. American journal of hypertension 20011201
[What do we think about selective estrogen receptor modulators?]. La Revue de medecine interne 20011201
A brief review of the International Breast Cancer Intervention Study (IBIS), the other current breast cancer prevention trials, and proposals for future trials. Annals of the New York Academy of Sciences 20011201
The MORE trial: multiple outcomes for raloxifene evaluation--breast cancer as a secondary end point: implications for prevention. Annals of the New York Academy of Sciences 20011201
The effects of estrogen and selective estrogen receptor modulators on cardiovascular risk factors. Annals of the New York Academy of Sciences 20011201
Selective estrogen receptor modulator effects on serum lipoproteins and vascular function in postmenopausal women and in hypercholesterolemic men. Annals of the New York Academy of Sciences 20011201
Rationale and overview of the Raloxifene Use for the Heart (RUTH) trial. Annals of the New York Academy of Sciences 20011201
Preventing and treating osteoporosis: strategies at the millennium. Annals of the New York Academy of Sciences 20011201
The paradox of small changes in bone density and reductions in risk of fracture with raloxifene. Annals of the New York Academy of Sciences 20011201
The effect of SERMs on the endometrium. Annals of the New York Academy of Sciences 20011201
Raloxifene: risks and benefits. Annals of the New York Academy of Sciences 20011201
The role of tamoxifen in breast cancer prevention: issues sparked by the NSABP Breast Cancer Prevention Trial (P-1). Annals of the New York Academy of Sciences 20011201
Chemoprevention with antiestrogens: the beginning of the end for breast cancer. Daniel G. Miller Lecture. Annals of the New York Academy of Sciences 20011201
Changes in biochemical markers of bone turnover in women treated with raloxifene: influence of regression to the mean. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20011201
Raloxifene versus continuous combined estrogen/progestin therapy: densitometric and biochemical effects in healthy postmenopausal Taiwanese women. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20011201
[The effect of raloxifene on bone tissue in postmenopausal women]. Polskie Archiwum Medycyny Wewnetrznej 20011201
[Risk-adapted therapy of osteoporosis. Preventing fractures]. MMW Fortschritte der Medizin 20011122
[Economic aspects of osteoporosis therapy. What does a prevented fracture cost?]. MMW Fortschritte der Medizin 20011122
The tamoxifen-responsive estrogen receptor alpha mutant D351Y shows reduced tamoxifen-dependent interaction with corepressor complexes. The Journal of biological chemistry 20011116
Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20011101
The relationship of health-related quality of life to prevalent and incident vertebral fractures in postmenopausal women with osteoporosis: results from the Multiple Outcomes of Raloxifene Evaluation Study. Arthritis and rheumatism 20011101
The role of serial bone mineral density testing for osteoporosis. Journal of women's health & gender-based medicine 20011101
Breast cancer chemoprevention: current clinical practice and future direction. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20011101
Evidence for an estrogen-like action of raloxifene upon the hypothalamic-pituitary unit: raloxifene inhibits luteinizing hormone secretion and stimulates prolactin secretion in ovariectomized female rats. Neuroscience letters 20011005
Selective estrogen receptor modulation and reduction in risk of breast cancer, osteoporosis, and coronary heart disease. Journal of the National Cancer Institute 20011003
Raloxifene and breast cancer. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20011002
Transcriptional activities of estrogen receptor alpha and beta in yeast properties of raloxifene. Biochemical pharmacology 20011001
Effects of long-term use of raloxifene, a selective estrogen receptor modulator, on thyroid function test profiles. Clinical chemistry 20011001
Role of tumor necrosis factor-alpha and interleukin-6 in the effects of hormone replacement therapy and raloxifene on C-reactive protein in postmenopausal women. The American journal of cardiology 20011001
Patterns of physician-reported diagnoses for women receiving raloxifene prescriptions. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20011001
Identification of a mutation in the human raloxifene response element of the transforming growth factor-beta 3 gene. Journal of Korean medical science 20011001
Does raloxifene reduce risk of vertebral fractures? Is this another, brighter way to treat osteoporosis? Canadian family physician Medecin de famille canadien 20011001
Neuroendocrine effects of raloxifene hydrochloride in postmenopausal women. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20011001
Breast cancer prevention: present and future. Cancer treatment reviews 20011001
Raloxifene for the treatment and prevention of breast cancer? Expert review of anticancer therapy 20011001
Evaluation and treatment of postmenopausal osteoporosis. The American journal of managed care 20010925
Risk-reduction mastectomy: clinical issues and research needs. Journal of the National Cancer Institute 20010905
Comparisons of the effects of tamoxifen, toremifene and raloxifene on enzyme induction and gene expression in the ovariectomised rat uterus. The Journal of endocrinology 20010901
Pharmacologic therapy for the treatment and prevention of osteoporosis. The Nursing clinics of North America 20010901
Effect of raloxifene on breast cancer cell Ki67 and apoptosis: a double-blind, placebo-controlled, randomized clinical trial in postmenopausal patients. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010901
Induction of the progesterone receptor gene in estrogen target cells monitored by branched DNA signal amplification. Steroids 20010901
Influence of smoking on the antiosteoporotic efficacy of raloxifene. The Journal of clinical endocrinology and metabolism 20010901
Randomized, double-blind, placebo-controlled study on effects of raloxifene and hormone replacement therapy on plasma no concentrations, endothelin-1 levels, and endothelium-dependent vasodilation in postmenopausal women. Arteriosclerosis, thrombosis, and vascular biology 20010901
Raloxifene reduces impedance to flow within the uterine artery in early postmenopausal women: a 2-year randomized, placebo-controlled, comparative study. American journal of obstetrics and gynecology 20010901
1-(2-[4-[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiol-3-ylcarbonyl]phenoxy]ethyl)piperidinium chloride. Acta crystallographica. Section C, Crystal structure communications 20010901
Selective estrogen-receptor modulators in 2001. Oncology (Williston Park, N.Y.) 20010901
Effect of raloxifene on serum triglycerides in postmenopausal women: influence of predisposing factors for hypertriglyceridemia. Clinical therapeutics 20010901
[New drugs]. Revue medicale de Bruxelles 20010901
Breast cancer prevention. Clinical obstetrics and gynecology 20010901
Update in general internal medicine. Annals of internal medicine 20010821
Design and methods of the Raloxifene Use for The Heart (RUTH) study. The American journal of cardiology 20010815
Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice. Synapse (New York, N.Y.) 20010801
Estrogen-like activity of tamoxifen and raloxifene on NMDA receptor binding and expression of its subunits in rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010801
Familiar drugs may prevent cancer. Postgraduate medical journal 20010801
Bone builders: preventing and treating osteoporosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801
Bone builders: the discoveries behind preventing and treating osteoporosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801
Adenomyosis--a result of disordered stromal differentiation. The American journal of pathology 20010801
Raloxifene-mediated increase in matrix metalloproteinase-1 production by activated monocytes. Arteriosclerosis, thrombosis, and vascular biology 20010801
Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres. Cytometry 20010801
Molecular identification of potential selective estrogen receptor modulator (SERM) like properties of phytoestrogens in the human breast cancer cell line MCF-7. Planta medica 20010801
Lack of substantial effects of raloxifene on thyroxine-binding globulin in postmenopausal women: dependency on thyroid status. Thyroid : official journal of the American Thyroid Association 20010801
Homocysteine in postmenopausal women and the importance of hormone replacement therapy. Clinical chemistry and laboratory medicine 20010801
Raloxifene encourages growth of ovarian cancer cells in vitro news. The Lancet. Oncology 20010801
Effects of raloxifene and hormone replacement therapy on markers of serum atherogenicity in healthy postmenopausal women. Maturitas 20010725
Raloxifene: handle with care. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010724
2-Amino-4,6-diarylpyridines as novel ligands for the estrogen receptor. Bioorganic & medicinal chemistry letters 20010723
Rheumatology: 15. Osteoporosis. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010710
Tamoxifen and contralateral breast cancer: the other side. Journal of the National Cancer Institute 20010704
Gonadotropins at menopause: the influence of obesity, insulin resistance, and estrogens. Steroids 20010701
Raloxifene effect on frequency of surgery for pelvic floor relaxation. Obstetrics and gynecology 20010701
Effects of raloxifene treatment on uterine leiomyomas in postmenopausal women. Fertility and sterility 20010701
Divergent effects of raloxifene HCI on the pharmacokinetics and pharmacodynamics of warfarin. Pharmaceutical research 20010701
[Hormone replacement and selective estrogen receptor modulators (SERMS) in the prevention and treatment of postmenopausal osteoporosis]. Der Orthopade 20010701
Indicators of lifetime estrogen exposure: effect on breast cancer incidence and interaction with raloxifene therapy in the multiple outcomes of raloxifene evaluation study participants. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010615
Chemoprevention of breast cancer. A joint guideline from the Canadian Task Force on Preventive Health Care and the Canadian Breast Cancer Initiative's Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010612
Oestrogenic effects of neonatal administration of raloxifene on hypothalamic-pituitary-gonadal axis in male and female rats. Reproduction (Cambridge, England) 20010601
Effect of physicians opinion on patients' choice of treatment. European journal of obstetrics, gynecology, and reproductive biology 20010601
Effects of the selective estrogen receptor modulator, raloxifene, on the somatotropic axis and insulin-glucose homeostasis. The Journal of clinical endocrinology and metabolism 20010601
Breast cancer chemoprevention: current status and future directions. Seminars in oncology 20010601
Tamoxifen to raloxifene and beyond. Seminars in oncology 20010601
Osteoporosis. Tennessee medicine : journal of the Tennessee Medical Association 20010601
NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy, March 7-29, 2000: highlights of the conference. Southern medical journal 20010601
Medication update. Southern medical journal 20010601
Estrogenic and antiestrogenic effects of raloxifene on collagen metabolism in breast cancer MCF-7 cells. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20010601
Tamoxifen, screening and new oestrogen receptor modulators. Best practice & research. Clinical obstetrics & gynaecology 20010601
Flexible alignment of small molecules. Journal of medicinal chemistry 20010510
Effect of tibolone and raloxifene on the tail temperature of oestrogen-deficient rats. European journal of pharmacology 20010504
Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor alpha complex. Cancer research 20010501
Effects of postmenopausal hormone replacement therapy on lipid, lipoprotein, and apolipoprotein (a) concentrations: analysis of studies published from 1974-2000. Fertility and sterility 20010501
Differential SERM activation of the estrogen receptors (ERalpha and ERbeta) at AP-1 sites. Chemistry & biology 20010501
Effects of the selective oestrogen receptor modulator-raloxifene-on calcium and PTH secretory dynamics in women with osteoporosis. Clinical endocrinology 20010501
Raloxifene for breast cancer prevention. JAMA 20010425
Raloxifene fails to slow cognitive decline in older women. Lancet (London, England) 20010421
Cognitive function in postmenopausal women treated with raloxifene. The New England journal of medicine 20010419
Can estrogen or selective estrogen-receptor modulators preserve cognitive function in elderly women? The New England journal of medicine 20010419
[SERM--selective estrogen receptor modulators]. Ugeskrift for laeger 20010409
Suggested rationale for prevention and treatment of glucocorticoid-induced bone loss in dermatologic patients. Archives of dermatology 20010401
[An alternative to postmenopausal Hormone Replacement Therapy? Selective Estrogens Receptors Modulators (SERMs)]. Minerva ginecologica 20010401
Estrogenic activity of tamoxifen and raloxifene on rat brain AMPA receptors. Neuroreport 20010305
A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial. The Journal of clinical endocrinology and metabolism 20010301
Raloxifene affects brain activation patterns in postmenopausal women during visual encoding. The Journal of clinical endocrinology and metabolism 20010301
Managing menopause after breast cancer: balancing risks and benefits. Cleveland Clinic journal of medicine 20010301
Comparative safety of bone remodeling agents with a focus on osteoporosis therapies. Journal of clinical pharmacology 20010301
Therapy for osteoporosis. Journal of the South Carolina Medical Association (1975) 20010301
SERMs and cardiovascular disease in women. How do these agents affect risk? Postgraduate medicine 20010301
Selective estrogen receptor modulators. An aid in unraveling the links between estrogen and breast cancer. Postgraduate medicine 20010301
Osteoporosis therapies for rheumatoid arthritis patients: minimizing gastrointestinal side effects. Seminars in arthritis and rheumatism 20010201
Randomized control study of the effects of raloxifene on serum lipids and homocysteine in older women. American journal of obstetrics and gynecology 20010201
The role of selective estrogen receptor modulators in the prevention and treatment of osteoporosis. Rheumatic diseases clinics of North America 20010201
An update on glucocorticoid-induced osteoporosis. Rheumatic diseases clinics of North America 20010201
[SERM-therapy in postmenopause. Protection of bone and breast]. MMW Fortschritte der Medizin 20010125
Estrogen, selective estrogen receptor modulation, and coronary heart disease: something or nothing. Journal of the National Cancer Institute 20010103
Digitized mammography: a clinical trial of postmenopausal women randomly assigned to receive raloxifene, estrogen, or placebo. Journal of the National Cancer Institute 20010103
Raloxifene and estrogen reduces progression of advanced atherosclerosis--a study in ovariectomized, cholesterol-fed rabbits. Atherosclerosis 20010101
Hormones and the brain: more studies. Harvard women's health watch 20010101
Raloxifene reverses bone loss in postmenopausal women with mild asymptomatic primary hyperparathyroidism. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010101
Estrogen and raloxifene activities on amyloid-beta-induced inflammatory reaction. Microvascular research 20010101
Drug information needs clarification. Canadian family physician Medecin de famille canadien 20010101
Chemoprevention of breast cancer. Southern medical journal 20010101
Chemoprevention of breast cancer. Cancer treatment and research 20010101
Breast cancer prevention study aims to overcome drug bias. JAMA 20010101
[Prevention of breast cancer--what are the latest developments?]. Harefuah 20010101
Breast cancer chemoprevention: beyond tamoxifen. Breast cancer research : BCR 20010101
Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Multiple outcomes of raloxifene evaluation. Breast cancer research and treatment 20010101
The prevention of breast cancer: an overview. Current medical research and opinion 20010101
Effects of SERMs on important indicators of cardiovascular health: lipoproteins, hemostatic factors, and endothelial function. Women's health issues : official publication of the Jacobs Institute of Women's Health 20010101
Raloxifene. Journal of bone and mineral metabolism 20010101
Regression to the mean: what does it mean? Using bone density results to monitor treatment of osteoporosis. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry 20010101
Cardiovascular effects of raloxifene hydrochloride. Cardiovascular drug reviews 20010101
Prevention and treatment of osteoporosis. Clinical medicine (London, England) 20010101
Initiation of osteoporosis treatment after bone mineral density testing. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20010101
Estradiol regulates monocyte chemotactic protein-1 in human coronary artery smooth muscle cells: a mechanism for its antiatherogenic effect. Menopause (New York, N.Y.) 20010101
From adjuvant therapy to breast cancer prevention: BCPT and STAR. The breast journal 20010101
Selective estrogen receptor modulation: the search for an ideal hormonal therapy for breast cancer. Cancer investigation 20010101
American Association of Clinical Endocrinologists 2001 Medical Guidelines for Clinical Practice for the Prevention and Management of Postmenopausal Osteoporosis. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20010101
Postmenopausal hormonal support: discontinuation of raloxifene versus estrogen. Menopause (New York, N.Y.) 20010101
Vertebral fractures: a hidden problem of osteoporosis. Medical science monitor : international medical journal of experimental and clinical research 20010101
Proliferative lesions of ovarian granulosa cells and reversible hormonal changes induced in rats by a selective estrogen receptor modulator. Toxicologic pathology 20010101
Mechanism of action and preclinical profile of raloxifene, a selective estrogen receptor modulation. Reviews in endocrine & metabolic disorders 20010101
The impact of risk on preference values: implications for evaluations of postmenopausal osteoporosis therapy. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20010101
Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats. Neoplasma 20010101
[New molecules]. Journal de pharmacie de Belgique 20010101
Raloxifene and endometrial cancer. Tumori 20010101
New strategies for the treatment of breast cancer. Breast cancer (Tokyo, Japan) 20010101
Proliferative lesions of ovarian granulosa cells and reversible hormonal changes induced in rats by a selective estrogen receptor modulator. Toxicologic pathology 20010101
Selective estrogen receptor modulators: mechanism of action and clinical experience. Focus on raloxifene. Reproduction, fertility, and development 20010101
Six and twelve month changes in bone turnover are related to reduction in vertebral fracture risk during 3 years of raloxifene treatment in postmenopausal osteoporosis. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20010101
[Antiestrogens: mechanism of action and clinical applications]. Salud publica de Mexico 20010101
Raloxifene: another selective estrogen modulator. In vivo (Athens, Greece) 20010101
Cancer prevention and early detection. Clinical journal of oncology nursing 20010101
Chemoprevention for high-risk women: tamoxifen and beyond. The breast journal 20010101
[Patients with fractures are in the front line for osteoporosis treatment but how to treat?]. Duodecim; laaketieteellinen aikakauskirja 20010101
Raloxifene and prevention of vertebral fracture (cont'd): mainly when oestrogen is contraindicated. Prescrire international 20001201
Raloxifene: results from the MORE study. Journal of musculoskeletal & neuronal interactions 20001201
Raloxifene: a review of its use in postmenopausal osteoporosis. Drugs 20000801
The effect of raloxifene on coronary arteries in aged ovariectomized ewes. Journal of veterinary pharmacology and therapeutics 20000601
[Raloxifene (Celvista, Evista)]. Revue medicale de Bruxelles 20000201
Estrogen synthesis in human colon cancer epithelial cells. The Journal of steroid biochemistry and molecular biology 19991231
Comparative analyses of mechanistic differences among antiestrogens. Endocrinology 19991201
The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. JAMA 19990616
Clinical effects of raloxifene hydrochloride in women. Annals of internal medicine 19990302
Tamoxifen for prevention of breast cancer. The Medical letter on drugs and therapeutics 19990101
An estrogen receptor basis for raloxifene action in bone. The Journal of steroid biochemistry and molecular biology 19990101
Raloxifene-associated hepatitis. Lancet (London, England) 19981107
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 19981001
Raloxifene. Drugs & aging 19980401
Superinduction of c-fos gene expression by estrogen in cultured guinea-pig endometrial cells requires priming by a cycloheximide-dependent mechanism. Endocrinology 19920901
Ligand dissociation from estrogen receptor is mediated by receptor dimerization: evidence from molecular dynamics simulations. Molecular endocrinology (Baltimore, Md.)
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