Detection of herplex simplex virus-1 and -2 in cardiac myxomas.

Journal of biomedicine & biotechnology 20120101

Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner.

PloS one 20120101

18F-FLT and 125I-IdUrd uptake increase in human tumour cell lines induced by the thymidylate synthase inhibitor FdUrd.

Nuklearmedizin. Nuclear medicine 20120101

Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.

PloS one 20120101

A systematic prediction of multiple drug-target interactions from chemical, genomic, and pharmacological data.

PloS one 20120101

The Link between Hypersensitivity Syndrome Reaction Development and Human Herpes Virus-6 Reactivation.

International journal of hepatology 20120101

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

PLoS computational biology 20111201

Dimethyl sulfoxide: an effective penetration enhancer for topical administration of NSAIDs.

The Physician and sportsmedicine 20110901

Compensation of depleted neuronal subsets by new neurons in a local area of the adult olfactory bulb.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20110720

Treatment of viral conjunctivitis with antiviral drugs.

Drugs 20110212

Dependence of cell survival on iododeoxyuridine concentration in 35-keV photon-activated Auger electron radiotherapy.

International journal of radiation oncology, biology, physics 20110101

Chemoenzymatic syntheses and anti-HIV-1 activity of glucose-nucleoside conjugates as prodrugs.

Bioconjugate chemistry 20101215

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug metabolism and disposition: the biological fate of chemicals 20101201

Antimicrobial activities of trimethoprim/sulfamethoxazole, 5-iodo-2'-deoxyuridine and rifampicin against Staphylococcus aureus.

International journal of antimicrobial agents 20101201

Application of bioluminescence imaging to therapeutic intervention of herpes simplex virus type I - Thymidine kinase/ganciclovir in glioma.

Cancer letters 20101101

Antiviral activity of various 1-(2'-deoxy-β-D-lyxofuranosyl), 1-(2'-fluoro-β-D-xylofuranosyl), 1-(3'-fluoro-β-D-arabinofuranosyl), and 2'-fluoro-2',3'-didehydro-2',3'-dideoxyribose pyrimidine nucleoside analogues against duck hepatitis B virus (DHBV) and human hepatitis B virus (HBV) replication.

Journal of medicinal chemistry 20101014

Antiviral Activity of 4'-thioIDU and Thymidine Analogs against Orthopoxviruses.

Viruses 20100901

Cardiomyogenesis in the adult human heart.

Circulation research 20100723

New trends in nucleoside biotechnology.

Acta naturae 20100701

Historical perspectives in the development of antiviral agents against poxviruses.

Viruses 20100601

Histopathologic validation of 3'-deoxy-3'-18F-fluorothymidine PET in squamous cell carcinoma of the oral cavity.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100501

In situ azide formation and 'click' reaction of nile red with DNA as an alternative postsynthetic route.

Chemical communications (Cambridge, England) 20100407

Selective impairments to memory consolidation in chicks produced by 5'-iodo-2'-deoxyuridine.

Neuroscience and behavioral physiology 20100201

Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: a dual birthdating analysis.

PloS one 20100101

Topical ganciclovir in the treatment of acute herpetic keratitis.

Clinical ophthalmology (Auckland, N.Z.) 20100101

Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.

The Cochrane database of systematic reviews 20100101

Immunofluorescent detection of two thymidine analogues (CldU and IdU) in primary tissue.

Journal of visualized experiments : JoVE 20100101

Acute ocular complications from self-administered topical kermes.

Middle East African journal of ophthalmology 20100101

Postherpetic neuralgia.

BMJ clinical evidence 20100101

Thymidine analog methods for studies of adult neurogenesis are not equally sensitive.

The Journal of comparative neurology 20091110

Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cells.

Cell cycle (Georgetown, Tex.) 20091001

Synthesis and enzymatic incorporation of modified deoxyuridine triphosphates.

Organic & biomolecular chemistry 20090921

Intracerebral delivery of 5-iodo-2'-deoxyuridine in combination with synchrotron stereotactic radiation for the therapy of the F98 glioma.

Journal of synchrotron radiation 20090701

The mismatch repair and base excision repair pathways: an opportunity for individualized (personalized) sensitization of cancer therapy.

Cancer biology & therapy 20090615

Modulation of the activity of methyl binding domain protein 4 (MBD4/MED1) while processing iododeoxyuridine generated DNA mispairs.

Cancer biology & therapy 20090601

Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research 20090315

Periocular dermatitis: a report of 401 patients.

Journal of the European Academy of Dermatology and Venereology : JEADV 20090201

First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR.

International journal of radiation biology 20081201

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal of medicinal chemistry 20081113

A stable niche supports long-term maintenance of human epidermal stem cells in organotypic cultures.

Stem cells (Dayton, Ohio) 20081001

Noggin expands neural stem cells in the adult hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910

On the lifetimes and physical nature of incompletely relaxed electrons in liquid water.

Physical chemistry chemical physics : PCCP 20080814

Radiation quality-dependent bystander effects elicited by targeted radionuclides.

The Journal of pharmacy and pharmacology 20080801

Preparation and preliminary evaluation of novel beta-cyclodextrin/IUDR prodrug formulations.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080618

Heavy element enhanced synchrotron stereotactic radiotherapy as a promising brain tumour treatment.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 20080601

A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.

Nature chemical biology 20080601

Enhanced experimental tumor metastasis with age in senescence-accelerated mouse.

Biological & pharmaceutical bulletin 20080501

Tumour cell proliferation under hypoxic conditions in human head and neck squamous cell carcinomas.

Oral oncology 20080401

Toxicology and pharmacokinetic study of orally administered 5-iodo-2-pyrimidinone-2'deoxyribose (IPdR) x 28 days in Fischer-344 rats: impact on the initial clinical phase I trial design of IPdR-mediated radiosensitization.

Cancer chemotherapy and pharmacology 20080201

Label-retaining cells in the rat submandibular gland.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20080101

Use of halogenated precursors for simultaneous DNA and RNA detection by means of immunoelectron and immunofluorescence microscopy.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20080101

Characterization of mouse 3T3-swiss albino cells available in Japan: necessity of quality control when used as feeders.

Japanese journal of infectious diseases 20080101

Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acid.

Journal of molecular signaling 20080101

Vaccinia virus lacking the deoxyuridine triphosphatase gene (F2L) replicates well in vitro and in vivo, but is hypersensitive to the antiviral drug (N)-methanocarbathymidine.

Virology journal 20080101

Isolation, characterization and genome sequence of a birnavirus strain from flounder Paralichthys olivaceus in China.

Archives of virology 20080101

Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.

Antiviral chemistry & chemotherapy 20080101

Effective synthesis of photosensitive oligodeoxynucleotides.

Nucleic acids symposium series (2004) 20080101

[Selective disruption of memory consolidation in chicks produced by 5'-iodo-2'-deoxyuridine].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20080101

Ganciclovir ophthalmic gel, 0.15%: a valuable tool for treating ocular herpes.

Clinical ophthalmology (Auckland, N.Z.) 20071201

Synthesis and evaluation of cis-1-[4-(hydroxymethyl)-2-cyclopenten-1-yl]-5-[(124)I]iodouracil: a new potential PET imaging agent for HSV1-tk expression.

Journal of medicinal chemistry 20071129

Probabilistic modeling of DNA mismatch repair effects on cell cycle dynamics and iododeoxyuridine-DNA incorporation.

Cancer research 20071115

Dermal delivery of selected hydrophilic drugs from elastic liposomes: effect of phospholipid formulation and surfactants.

The Journal of pharmacy and pharmacology 20070901

Collisionally-induced dissociation of substituted pyrimidine antiviral agents: mechanisms of ion formation using gas phase hydrogen/deuterium exchange and electrospray ionization tandem mass spectrometry.

Journal of the American Society for Mass Spectrometry 20070801

Concomitant quantification of targeted drug delivery and biological response in individual cells.

BioTechniques 20070701

Replication labeling with halogenated thymidine analogs.

Current protocols in cell biology 20070601

High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny.

PLoS biology 20070501

Growth and regeneration of adult beta cells does not involve specialized progenitors.

Developmental cell 20070501

Phosphine containing oligonucleotides for the development of metallodeoxyribozymes.

Chemical communications (Cambridge, England) 20070421

Does (124)Iodo-deoxyuridine measure cell proliferation in NSCLC? Initial investigations with PET imaging and radio-metabolite analysis.

European journal of nuclear medicine and molecular imaging 20070201

Therapeutic interventions for herpes simplex virus epithelial keratitis.

The Cochrane database of systematic reviews 20070124

Iododeoxyuridine uptake in proliferating smooth muscle cells in vitro.

Journal of vascular and interventional radiology : JVIR 20070101

Effects of DNA-targeted ionizing radiation produced by 5-[125I]iodo-2'-deoxyuridine on global gene expression in primary human cells.

BMC genomics 20070101

Supported synthesis and functionnalization of 2''-deoxyuridine by Suzuki-Miyaura cross-coupling.

Nucleosides, nucleotides & nucleic acids 20070101

Postherpetic neuralgia.

BMJ clinical evidence 20070101

Microarray analysis of differentially expressed genes after exposure of normal human fibroblasts to ionizing radiation from an external source and from DNA-incorporated iodine-125 radionuclide.

Gene 20061101

Distinct thymidine kinases encoded by cowpox virus and herpes simplex virus contribute significantly to the differential antiviral activity of nucleoside analogs.

Antiviral research 20060801

Corneal ulceration associated with naturally occurring canine herpesvirus-1 infection in two adult dogs.

Journal of the American Veterinary Medical Association 20060801

The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine.

Cancer research 20060801

Absence of an immediate G1/S checkpoint in primary MEFs following gamma-irradiation identifies a novel checkpoint switch.

Cell cycle (Georgetown, Tex.) 20060801

Toward orthopoxvirus countermeasures: a novel heteromorphic nucleoside of unusual structure.

Journal of medicinal chemistry 20060713

SNP genotyping by using photochemical ligation.

Angewandte Chemie (International ed. in English) 20060703

Combined antiherpetic effect of complex preparation 'Viferon-eye drops' and modified nucleosides.

Bulletin of experimental biology and medicine 20060601

Short fluorodeoxyuridine exposure of different human glioblastoma lines induces high-level accumulation of S-phase cells that avidly incorporate 125I-iododeoxyuridine.

European journal of nuclear medicine and molecular imaging 20060501

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Hypoxia in human colorectal adenocarcinoma: comparison between extrinsic and potential intrinsic hypoxia markers.

International journal of radiation oncology, biology, physics 20060501

Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence.

Molecular cancer therapeutics 20060401

3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.

Bioorganic & medicinal chemistry letters 20060215

Hypoxia in relation to vasculature and proliferation in liver metastases in patients with colorectal cancer.

International journal of radiation oncology, biology, physics 20060201

Antiviral prodrugs - the development of successful prodrug strategies for antiviral chemotherapy.

British journal of pharmacology 20060101

The interaction between two radiosensitizers: 5-iododeoxyuridine and caffeine.

Cancer research 20060101

On systems and control approaches to therapeutic gain.

BMC cancer 20060101

In vitro comparison of antiviral drugs against feline herpesvirus 1.

BMC veterinary research 20060101

Reversible inactivation of the transcriptional function of P53 protein by farnesylation.

BMC biotechnology 20060101

Synergistic combination effect of cidofovir and idoxuridine on vaccinia virus replication.

Antiviral chemistry & chemotherapy 20060101

Genome-wide gene expression changes in normal human fibroblasts in response to low-LET gamma-radiation and high-LET-like 125IUdR exposures.

Radiation protection dosimetry 20060101

Measuring proliferation in breast cancer: practicalities and applications.

Breast cancer research : BCR 20060101

Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.

Bioorganic & medicinal chemistry 20051215

BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.

Cancer research 20051215

Schedule-dependent drug effects of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as an in vivo radiosensitizer in U251 human glioblastoma xenografts.

Clinical cancer research : an official journal of the American Association for Cancer Research 20051015

A novel method to synthesize versatile multiple-branched DNA (MB-DNA) by reversible photochemical ligation.

Chembiochem : a European journal of chemical biology 20051001

Overexpression of p27 Kip 1, probability of cell cycle exit, and laminar destination of neocortical neurons.

Cerebral cortex (New York, N.Y. : 1991) 20050901

Radiosynthesis, in vitro cellular uptake and in vivo biodistribution of 3'-O-(3-benzenesulfonylfuroxan-4-yl)-5-[125I]iodo-2'-deoxyuridine, a nucleoside-based nitric oxide donor.

Nuclear medicine and biology 20050801

Thymidine analogues to assess microperfusion in human tumors.

International journal of radiation oncology, biology, physics 20050715

Therapeutic options for herpes labialis: experimental and natural therapies.

Cutis 20050701

Rapid quantitation of plasma 2'-deoxyuridine by high-performance liquid chromatography/atmospheric pressure chemical ionization mass spectrometry and its application to pharmacodynamic studies in cancer patients.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050605

5-[123I/125I]iodo-2'-deoxyuridine in metastatic lung cancer: radiopharmaceutical formulation affects targeting.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050501

DNA uptake of 131I-iododeoxyuridine.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050501

DNA-incorporated 125I induces more than one double-strand break per decay in mammalian cells.

Radiation research 20050401

Modulation of 5-fluorouracil cytotoxicity through thymidylate synthase and NF-kappaB down-regulation and its application on the radiolabelled iododeoxyuridine therapy on human hepatoma cell.

Biochemical pharmacology 20050215

Modeling multicellular response to nonuniform distributions of radioactivity: differences in cellular response to self-dose and cross-dose.

Radiation research 20050201

Low doses of bromo- and iododeoxyuridine produce near-saturation labeling of adult proliferative populations in the dentate gyrus.

The European journal of neuroscience 20050201

Colocalization of carbonic anhydrase 9 expression and cell proliferation in human head and neck squamous cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research 20050101

[Antiherpetic therapy].

Oftalmologia (Bucharest, Romania : 1990) 20050101

Effects of single-pulse (< or = 1 ps) X-rays from laser-produced plasmas on mammalian cells.

Journal of radiation research 20041201

Synthesis and antiviral activities of 1'-carbon-substituted 4'-thiothymidines.

Bioorganic & medicinal chemistry 20041015

[Therapeutic effect of 125IUdR on the glioma cell line C6 in vitro and in vivo].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20040901

Synchrotron radiation-based experimental determination of the optimal energy for cell radiotoxicity enhancement following photoelectric effect on stable iodinated compounds.

British journal of cancer 20040802

New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking study.

RNA (New York, N.Y.) 20040801

Tracers to monitor the response to chemotherapy: in vitro screening of four radiopharmaceuticals.

Cancer biotherapy & radiopharmaceuticals 20040801

Topical liposomal gel of idoxuridine for the treatment of herpes simplex: pharmaceutical and clinical implications.

Pharmaceutical development and technology 20040801

Targeted radiosensitisation by pegylated liposome-encapsulated 3', 5'-O-dipalmitoyl 5-iodo-2'-deoxyuridine in a head and neck cancer xenograft model.

British journal of cancer 20040719

Continuous 28-day iododeoxyuridine infusion and hyperfractionated accelerated radiotherapy for malignant glioma: a phase I clinical study.

International journal of radiation oncology, biology, physics 20040715

Positive interactive radiosensitisation in vitro with the combination of two nucleoside analogues, (E)-2'-deoxy-2'-(fluoromethylene) cytidine and iododeoxyuridine.

European journal of cancer (Oxford, England : 1990) 20040701

Antiviral drugs in current clinical use.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20040601

Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts.

International journal of cancer 20040520

The preparation of clinical grade 5-[123I]iodo-2'-deoxyuridine and 5-[125I]iodo-2'-deoxyuridine with high in vitro stability and the potential for early proliferation scintigraphy.

Nuclear medicine communications 20040501

Indian hedgehog: a mechanotransduction mediator in condylar cartilage.

Journal of dental research 20040501

[The latest in herpes simplex keratitis therapy].

Journal francais d'ophtalmologie 20040501

In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1.

American journal of veterinary research 20040401

Design and synthesis of 3'- and 5'-O-(3-benzenesulfonylfuroxan-4-yl)-2'-deoxyuridines: biological evaluation as hybrid nitric oxide donor-nucleoside anticancer agents.

Journal of medicinal chemistry 20040325

Feasibility of sodium/iodide symporter gene as a new imaging reporter gene: comparison with HSV1-tk.

European journal of nuclear medicine and molecular imaging 20040301

Antisense thymidylate synthase electrogene transfer to increase uptake of radiolabeled iododeoxyuridine in a murine model.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040301

Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20040218

Suppression of generation and replication of acyclovir-resistant herpes simplex virus by a sensitive virus.

Journal of medical virology 20040101

In vivo comparison of IVDU and IVFRU in HSV1-TK gene expressing tumor bearing rats.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20040101

Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides.

Nucleosides, nucleotides & nucleic acids 20040101

Polyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorption.

BMC cell biology 20040101

Is coulomb explosion a damaging mechanism for (125)IUdR?

International journal of radiation biology 20040101

Activation of diverse pathways to apoptosis by (125)IdUrd and gamma-photon exposure.

International journal of radiation biology 20040101

GammaH2AX foci induced by gamma rays and 125idU decay.

International journal of radiation biology 20040101

Therapeutic potential of 5-[125I]iodo-2'-deoxyuridine and methotrexate in the treatment of advanced neoplastic meningitis.

International journal of radiation biology 20040101

Dose-dependent pharmacokinetics of 1-(2-deoxy-beta-D- ribofuranosyl)-2,4-difluoro-5-iodobenzene: a potential mimic of 5-iodo-2'-deoxyuridine.

Biopharmaceutics & drug disposition 20031201

Postherpetic neuralgia.

Clinical evidence 20031201

Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine.

Journal of medicinal chemistry 20031106

Use of radiolabelled iododeoxyuridine as adjuvant treatment for experimental tumours of the liver.

The British journal of surgery 20031001

Role of MutSalpha in the recognition of iododeoxyuridine in DNA.

Cancer research 20030901

Efficient one-step Suzuki arylation of unprotected halonucleosides, using water-soluble palladium catalysts.

The Journal of organic chemistry 20030822

Study on the possibility of insulin as a carrier of IUdR for hepatocellular carcinoma-targeted therapy.

World journal of gastroenterology 20030815

Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.

Chembiochem : a European journal of chemical biology 20030804

Exploration of the influence of 5-iodo-2'-deoxyuridine incorporation on the structure of d[CACG(IDU)G].

Acta crystallographica. Section D, Biological crystallography 20030801

Biochemical and pharmacokinetic evaluation of a novel pyrimidine nucleoside nitric oxide donor as a potential anticancer/antiviral agent.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030701

Postherpetic neuralgia.

Clinical evidence 20030601

A simple and efficient method for synthesis of 5-substituted 2'-deoxyuridine nucleosides using metal-halogen exchange reaction of 5-iodo-2'-deoxyuridine sodium salt.

Chemical communications (Cambridge, England) 20030507

Clinical significance of atomic inner shell ionization (ISI) and Auger cascade for radiosensitization using IUdR, BUdR, platinum salts, or gadolinium porphyrin compounds.

International journal of radiation oncology, biology, physics 20030315

Synthesis of 3'- and 5'-nitrooxy pyrimidine nucleoside nitrate esters: 'nitric oxide donor' agents for evaluation as anticancer and antiviral agents.

Journal of medicinal chemistry 20030313

Randomized, open-labelled comparison between an idoxuridine 10% gel and acyclovir 5% cream in recurrent herpes labialis.

Journal of the European Academy of Dermatology and Venereology : JEADV 20030301

Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization.

Cancer research 20030215

Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resistance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents.

Journal of virology 20030201

Protease-activated receptor (PAR)-1 and PAR-2 participate in the cell growth of alveolar capillary endothelium in primary lung adenocarcinomas.

Cancer 20030201

Preclinical Auger and gamma radiation dosimetry for fluorodeoxyuridine-enhanced tumour proliferation scintigraphy with [123I]iododeoxyuridine.

European journal of nuclear medicine and molecular imaging 20030201

Novel agents and strategies to treat herpes simplex virus infections.

Expert opinion on investigational drugs 20030201

A balanced deoxyribonucleoside mixture increased the rate of DNA incorporation of 5-[125I]Iodo-2'-deoxyuridine in glioblastoma cells.

Cancer biotherapy & radiopharmaceuticals 20030201

[Anti-herpetic chemotherapeutic drugs].

Nihon rinsho. Japanese journal of clinical medicine 20030201

In vitro activity of potential anti-poxvirus agents.

Antiviral research 20030101

Biliary obstruction reduces hepatic killing and phagocytic clearance of circulating microorganisms in rats.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20030101

Functional expression of a sodium dependent nucleoside transporter on rabbit cornea: Role in corneal permeation of acyclovir and idoxuridine.

Current eye research 20030101

Interventions for herpes simplex virus epithelial keratitis.

The Cochrane database of systematic reviews 20030101

Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.

Nucleosides, nucleotides & nucleic acids 20030101

HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors.

International journal of radiation oncology, biology, physics 20021201

PET imaging drug distribution after intratumoral injection: the case for (124)I-iododeoxyuridine in malignant gliomas.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20021101

Modelling the effect of incorporated halogenated pyrimidine on radiation-induced DNA strand breaks.

International journal of radiation biology 20021101

Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody.

Radiation research 20021001

Effect of 5-iodo-2'-deoxyuridine on vaccinia virus (orthopoxvirus) infections in mice.

Antimicrobial agents and chemotherapy 20020901

Metallocene-DNA: synthesis, molecular and electronic structure and DNA incorporation of C5-ferrocenylthymidine derivatives.

Chemistry (Weinheim an der Bergstrasse, Germany) 20020702

Clustered sites of DNA repair synthesis during early nucleotide excision repair in ultraviolet light-irradiated quiescent human fibroblasts.

Experimental cell research 20020610

Cell kinetic changes in human squamous cell carcinomas during radiotherapy studied using the in vivo administration of two halogenated pyrimidines.

European journal of cancer (Oxford, England : 1990) 20020501

A new bacilliform fathead minnow rhabdovirus that produces syncytia in tissue culture.

Archives of virology 20020501

Enhanced inhibition of orthopoxvirus replication in vitro by alkoxyalkyl esters of cidofovir and cyclic cidofovir.

Antimicrobial agents and chemotherapy 20020401

Unlabelled iododeoxyuridine increases the rate of uptake of [125I]iododeoxyuridine in human xenografted glioblastomas.

European journal of nuclear medicine and molecular imaging 20020401

Temporal changes in the distribution of thoracic duct lymphoblasts to synovium and other tissues of rats with adjuvant-induced arthritis.

Immunology and cell biology 20020401

Induction of chromosome aberrations in unirradiated chromatin after partial irradiation of a cell nucleus.

International journal of radiation biology 20020401

Pharmacokinetics and metabolism of the novel synthetic C-nucleoside, 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-iodobenzene: a potential mimic of 5-iodo-2'-deoxyuridine.

Biopharmaceutics & drug disposition 20020401

New oligoethylene ester derivatives of 5-iodo-2'-deoxyuridine as dermal prodrugs: synthesis, physicochemical properties, and skin permeation studies.

Journal of pharmaceutical sciences 20020101

[Chromosomal abnormalities in lymphocytes from a patient with Werner's syndrome in intact culture and after treatment with halogenated analogs of thymidine].

Tsitologiia 20020101

Genomic variations among wildtype and mutant strains of pseudorabies virus.

Revista Argentina de microbiologia 20020101

Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive cooperativity. Application of micro-array analysis.

BMC infectious diseases 20020101

Ratio of complex double strand break damage induced by 125IUdR and 123IUdR correlates with experimental in vitro cell killing effectiveness.

Radiation protection dosimetry 20020101

ICCVAM evaluation of the murine local lymph node assay. Conclusions and recommendations of an independent scientific peer review panel.

Regulatory toxicology and pharmacology : RTP 20011201

Early detection of endogenous retroviruses in chemically induced mouse cells.

Virus research 20011105

Fluorodeoxyuridine improves imaging of human glioblastoma xenografts with radiolabeled iododeoxyuridine.

Cancer research 20011101

Synthesis and biological investigations of 5-substituted pyrimidine nucleosides coupled to a dihydropyridine/pyridinium salt redox chemical delivery system.

Archiv der Pharmazie 20011101

Targeting DNA mismatch repair for radiosensitization.

Seminars in radiation oncology 20011001

Cytotoxicity of 125I-oestrogen decay in non-oestrogen receptor-expressing human breast cancer cells, MDA-231 and oestrogen receptor-expressing MCF-7 cells.

International journal of radiation biology 20010901

Monte Carlo simulations and measurement of DNA damage from x-ray-triggered auger cascades in iododeoxyuridine (IUdR).

Radiation and environmental biophysics 20010901

Antiviral drugs: current state of the art.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20010801

Recruitment of mononuclear leucocytes to osteoarthritic human synovial xenografts in the ears of SCID mice.

Immunology and cell biology 20010801

Increased glomerular Vwf after kidney irradiation is not due to increased biosynthesis or endothelial cell proliferation.

Radiation research 20010701

Laser-induced photo-cross-linking of cisplatin-modified DNA to HMG-domain proteins.

Biochemistry 20010626

A flow cytometry technique for measuring chromosome-mediated gene transfer.

Cytometry 20010601

Contact dermatitis from topical antiviral drugs.

Contact dermatitis 20010501

Chemical modification of 5-[125I]iodo-2'-deoxyuridine toxicity in mammalian cells in vitro.

International journal of radiation biology 20010501

[[(18)F]N-(4'-fluorobenzyl)-4-(3-bromophenyl) acetamide for imaging the sigma receptor status of tumors: comparison with [(18)F]FDG, and [(125)I]IUDR.

Nuclear medicine and biology 20010501

Phase I trial of sequential administration of raltitrexed (Tomudex) and 5-iodo-2'-deoxyuridine (IdUrd).

Annals of oncology : official journal of the European Society for Medical Oncology 20010501

Targets for radiation-induced cell death: when DNA damage doesn't kill.

Radiation research 20010401

Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.

Clinical microbiology reviews 20010401

Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.

Pain 20010201

Is there a future for cell kinetic measurements using IdUrd or BdUrd?

International journal of radiation oncology, biology, physics 20010201

Relative biological effectiveness of accumulated 125IdU and 125I-estrogen decays in estrogen receptor-expressing MCF-7 human breast cancer cells.

Radiation research 20010201

Preclinical evaluation of locoregional delivery of radiolabeled iododeoxyuridine and thymidylate synthase inhibitor in a hepatoma model.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20010201

Laser cytometry of human tissues and tumors: proliferation and therapeutic applications.

Methods in cell biology 20010101

Antizona and antisperm antibodies in women with endometriosis and/or infertility.

Fertility and sterility 20010101

In vitro effects of antiviral agents on human keratocytes.

Cornea 20010101

Interventions for herpes simplex virus epithelial keratitis.

The Cochrane database of systematic reviews 20010101

Efficient in-vitro transfer of a 60-Mb mammalian artificial chromosome into murine and hamster cells using cationic lipids and dendrimers.

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20010101

Pert analysis of endogenous retroviruses induced from K-BALB mouse cells treated with 5-iododeoxyuridine: a potential strategy for detection of inducible retroviruses from vaccine cell substrates.

Developments in biologicals 20010101

Hypoxia and perfusion measurements in human tumors--initial experience with pimonidazole and IUdR.

Acta oncologica (Stockholm, Sweden) 20010101

Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes.

The Biochemical journal 20001015

Ataxia telangiectasia-mutated gene product inhibits DNA damage-induced apoptosis via ceramide synthase.

The Journal of biological chemistry 19990618

Comparison of spontaneous and idoxuridine-induced micronuclei by chromosome painting.

Mutation research 19990406

Efficacy of select antivirals against Cryptosporidium parvum in vitro.

FEMS microbiology letters 19981101

Radiopharmaceuticals (Strontium 89) and radiosensitizers (idoxuridine).

Journal of intravenous nursing : the official publication of the Intravenous Nurses Society 19980101

Structure-activity relationship of the affinity of 5-substituted uracil nucleoside analogues for varicella-zoster virus thymidine kinase and their activity against varicella-zoster virus.

Antiviral research 19970801

Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells.

The Biochemical journal 19960715

Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.

Antiviral research 19951201

Lack of stereospecificity of some cellular and viral enzymes involved in the synthesis of deoxyribonucleotides and DNA: molecular basis for the antiviral activity of unnatural L-beta-nucleosides.

Biochimie 19950101

Tricyclic analogues of acyclovir and ganciclovir. Influence of substituents in the heterocyclic moiety on the antiviral activity.

Journal of medicinal chemistry 19940916

Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.

Journal of medicinal chemistry 19930709

Metabolism and mode of selective inhibition of human immunodeficiency virus replication by 3'-azido-2',3'-dideoxy-5-iodouridine and 3'-azido-2',3'-dideoxy-5-bromouridine.

Biochemical pharmacology 19930107

In vitro antiviral activity of polyoxotungstate (PM-19) and other polyoxometalates against herpes simplex virus.

Antiviral research 19911201

The effect of radiosensitizers on radio-immunotherapy, using 131I-labelled anti-CEA antibodies in a human colonic xenograft model.

International journal of cancer 19910220

In vitro screening for antiretroviral agents against simian immunodeficiency virus (SIV).

Antiviral research 19900801

Phorbol ester-mediated induction of HIV-1 from a chronically infected promonocyte clone: blockade by protein kinase inhibitors and relationship to tat-directed trans-activation.

Biochemical and biophysical research communications 19900115

Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine.

Journal of medicinal chemistry 19890801

Synthesis and antiviral activity of phosphonoacetic and phosphonoformic acid esters of 5-bromo-2'-deoxyuridine and related pyrimidine nucleosides and acyclonucleosides.

Journal of medicinal chemistry 19890201

Inhibition of herpes simplex virus infection by tannins and related compounds.

Antiviral research 19890101

Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity.

Journal of medicinal chemistry 19880901

Efficacies of antiherpesvirus nucleosides against two strains of herpes simplex virus type 1 in Vero and human embryo lung fibroblast cells.

Antimicrobial agents and chemotherapy 19880701

2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity.

Journal of medicinal chemistry 19870701

In vitro and in vivo antiviral activity of 2'-fluorinated arabinosides of 5-(2-haloalkyl)uracil.

Antiviral research 19870601

Inhibiting effect of (RS)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine on varicella-zoster virus replication in cell culture.

Antimicrobial agents and chemotherapy 19870101

Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.

Journal of medicinal chemistry 19860701

Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs.

Antimicrobial agents and chemotherapy 19860301

Interaction of monoclonal antibodies directed against bromodeoxyuridine with pyrimidine bases, nucleosides, and DNA.

Journal of immunology (Baltimore, Md. : 1950) 19860301

5-(Haloalkyl)-2'-deoxyuridines: a novel type of potent antiviral nucleoside analogue.

Journal of medicinal chemistry 19851101

Selective in vitro and in vivo activities of 5-(2-haloalkyl)pyrimidine nucleoside analogs, particularly 5-(2-chloroethyl)-2'-deoxyuridine, against herpes simplex virus.

Antimicrobial agents and chemotherapy 19850801

Synthesis and antiviral activity of the carbocyclic analogues of (E)-5-(2-halovinyl)-2'-deoxyuridines and (E)-5-(2-halovinyl)-2'-deoxycytidines.

Journal of medicinal chemistry 19850501

Synthesis and antiviral activity of carbocyclic analogues of 2'-deoxyribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines.

Journal of medicinal chemistry 19841101

Nucleic acid related compounds. 47. Synthesis and biological activities of pyrimidine and purine 'acyclic' nucleoside analogues.

Journal of medicinal chemistry 19841101

Pyrazolo[4,3-d]pyrimidine nucleosides. Synthesis and antiviral activity of 1-beta-D-ribofuranosyl-3-methyl-6-substituted-7H-pyrazolo[4,3-d]pyr imi din-7-ones.

Journal of medicinal chemistry 19840801

In vitro and in vivo antiviral activity of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) and related compounds.

Antiviral research 19840601

Strains of varicella-zoster virus resistant to 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil.

Antimicrobial agents and chemotherapy 19840601

Synthesis of (E)-5-(3,3,3-trifluoro-1-propenyl)-2'-deoxyuridine and related analogues: potent and unusually selective antiviral activity of (E)-5-(3,3,3-trifluoro-1-propenyl)-2'-deoxyuridine against herpes simplex virus type 1.

Journal of medicinal chemistry 19840301

Antiherpes activity of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil and some other 5-substituted uracil arabinosyl nucleosides in two different cell lines.

Antiviral research 19830901

Activity of 1-(2'-fluoro-2'-deoxy-beta-D-arabinofuranosyl)thymine against herpes simplex virus in cell cultures and rabbit eyes.

Antimicrobial agents and chemotherapy 19830601

Nucleic acid related compounds. 40. Synthesis and biological activities of 5-alkynyluracil nucleosides.

Journal of medicinal chemistry 19830501

Synthesis and antiviral activity of water-soluble esters of acyclovir [9-[(2-hydroxyethoxy)methyl]guanine].

Journal of medicinal chemistry 19830401

Carbocyclic analogues of 5-substituted uracil nucleosides: synthesis and antiviral activity.

Journal of medicinal chemistry 19830201

Synthesis of some 5'-amino-2',5'-dideoxy-5-iodouridine derivatives and their antiviral properties against herpes simplex virus.

Antiviral research 19821201

Synthesis and antiviral properties of some 2'-deoxy-5-(fluoroalkenyl)uridines.

Journal of medicinal chemistry 19821101

A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2.

Antimicrobial agents and chemotherapy 19820701

Efficiency and selectivity of (E)-5-(2-bromovinyl)-2'-deoxyuridine and some other 5-substituted 2'-deoxypyrimidine nucleosides as anti-herpes agents.

Antiviral research 19820501

Inhibitory effects of antiherpesviral thymidine analogs against varicella-zoster virus.

Antimicrobial agents and chemotherapy 19820201

In vitro susceptibility of varicella-zoster virus to E-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.

Antimicrobial agents and chemotherapy 19820101

Antiherpesviral and anticellular effects of 1-beta-D-arabinofuranosyl-E-5-(2-halogenovinyl) uracils.

Antimicrobial agents and chemotherapy 19810701

Synthesis and antiherpetic activity of some 4-[(aryloxy)alkyl]pyrazoles.

Journal of medicinal chemistry 19810601

Synthesis and antiviral activity of 5-[(cyanomethylene)oxy]-2'-deoxyuridine.

Journal of medicinal chemistry 19810401

Antiviral, antitumor, and thymidylate synthetase inhibition studies of 5-substituted styryl derivatives of 2'-deoxyuridine and their 5'-phosphates.

Biochemical pharmacology 19810301

Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with adenine arabinoside, 5-ethyldeoxyuridine, 5-iododeoxyuridine, and phosphonoacetic acid against herpes simplex virus types 1 and 2.

Antimicrobial agents and chemotherapy 19800401

Synthesis of 5-[(methylthio)methyl]-2'-deoxyuridine, the corresponding sulfoxide and sulfone, and their 5'-phosphates: antiviral effects and thymidylate synthetase inhibition.

Journal of medicinal chemistry 19800301

In vitro and in vivo resistance of herpes simplex virus to 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine).

Antimicrobial agents and chemotherapy 19800201

(E)-5-(2-bromovinyl)-2'-Deoxyuridine in the treatment of experimental herpes simplex keratitis.

Antimicrobial agents and chemotherapy 19800101

Antiviral activity of 5-methylthiomethyl-2'-deoxyuridine and other 5-substituted 2'-deoxyuridines.

Biochemical pharmacology 19791115

Relative potencies of different anti-herpes agents in the topical treatment of cutaneous herpes simplex virus infection of athymic nude mice.

Antimicrobial agents and chemotherapy 19791101

Antiviral and antineoplastic activities of pyrimidine arabinosyl nucleosides and their 5'-amino derivatives.

Journal of medicinal chemistry 19791001

In vitro antiherpesviral activity of 5-alkyl derivatives of 1-beta-D-arabinofuranosyluracil.

Antimicrobial agents and chemotherapy 19790801

Effect of 5-iodo-5'-amino-2',5'-dideoxyuridine on varicella-zoster virus in vitro.

Antimicrobial agents and chemotherapy 19790701

(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.

Proceedings of the National Academy of Sciences of the United States of America 19790601

Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides.

Journal of medicinal chemistry 19790101

Effects of nucleoside analogs on Epstein-Barr virus-induced transformation of human umbilical cord leukocytes and Epstein-Barr virus expression in transformed cells.

Antimicrobial agents and chemotherapy 19790101

Effect of 9-(2-hydroxyethoxymethyl)guanine on herpesvirus-induced keratitis and iritis in rabbits.

Antimicrobial agents and chemotherapy 19781201

Trisodium phosphonoformate, a new antiviral compound.

Science (New York, N.Y.) 19780901

9-(2-hydroxyethoxymethyl) guanine activity against viruses of the herpes group.

Nature 19780413

5-Propyl-2'-deoxyuridine: a specific anti-herpes agent.

Antimicrobial agents and chemotherapy 19780301

5-O-Alkylated derivatives of 5-hydroxy-2'-deoxyuridine as potential antiviral agents. Anti-herpes activity of 5-propynyloxy-2'-deoxyuridine.

Journal of medicinal chemistry 19780201

Improved synthesis and in vitro antiviral activities of 5-cyanouridine and 5-cyano-2'-deoxyuridine.

Journal of medicinal chemistry 19770701

Antiviral activity of some beta-diketones. 1. Aryl alkyl diketones. In vitro activity against both RNA and DNA viruses.

Journal of medicinal chemistry 19770601

Antiviral activity of some beta-diketones. 2. Aryloxy alkyl diketones. In vitro activity against both RNA and DNA viruses.

Journal of medicinal chemistry 19770601

Antiviral activities of acyl derivatives of 2,2'-anhydro-1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosylcytosine in cell culture.

Antimicrobial agents and chemotherapy 19770201

Effect of cytosine, arabinoside, iododeoxyuridine, ethyldeoxyuridine, thiocyanatodeoxyuridine, and ribavirin on tail lesion formation in mice infected with vaccinia virus.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19760301

Antiviral and antimetabolic activities of formycin and its N1-, N2-, 2'-O- and 3'-O-methylated derivatives.

Biochemical pharmacology 19751001

Bioassay of alkyl halides and nucleotide base analogs by pulmonary tumor response in strain A mice.

Cancer research 19750601

Selective inhibition of herpes simplex virus by 5-amino-2,5-dideoxy-5-iodouridine.

Journal of virology 19750501

Taratogenic effects of the pyrimidine analogues 5-iododeoxyuridine and cytosine arabinoside in late fetal mice and rats.

Teratology 19750201

Assessment of cytosine arabinoside as an antiviral agent in humans.

Antimicrobial agents and chemotherapy 19741101

Herpes simplex virus skin infection in hairless mice: treatment with antiviral compounds.

Antimicrobial agents and chemotherapy 19740301

Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium aphidicola.

Antimicrobial agents and chemotherapy 19730901

In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses.

Antimicrobial agents and chemotherapy 19730201

The antiviral activity of 9-beta-D-arabinofuranosyladenine (ARA-A).

Chemotherapia 19680101

Nucleosides. 3. Studies on 5-methylamino-2'-deoxyuridine as a specific antiherpes agent.

Journal of medicinal chemistry 19660501