(3α,5α)-3-Hydroxypregnan-20-one
| Title | Journal |
|---|---|
| Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype. | Hepatology (Baltimore, Md.) 20130201 |
| Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. | Toxicological sciences : an official journal of the Society of Toxicology 20121201 |
| Allopregnanolone regulates neurogenesis and depressive/anxiety-like behaviour in a social isolation rodent model of chronic stress. | Neuropharmacology 20121201 |
| Neuroactive steroids with perfluorobenzoyl group. | Steroids 20121001 |
| Discriminative stimulus effects of pregnanolone in rats: role of training dose in determining mechanism of action. | Psychopharmacology 20120901 |
| Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration. | Neuropharmacology 20120901 |
| Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice. | Neurobiology of aging 20120801 |
| Allopregnanolone protects against dopamine-induced striatal damage after in vitro ischaemia via interaction at GABA A receptors. | Journal of neuroendocrinology 20120801 |
| Long-term administration with levonorgestrel decreases allopregnanolone levels and alters GABA(A) receptor subunit expression and anxiety-like behavior. | Pharmacology, biochemistry, and behavior 20120801 |
| Progesterone receptors: a key for neuroprotection in experimental stroke. | Endocrinology 20120801 |
| Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone. | Human molecular genetics 20120701 |
| Allopregnanolone alters the luteinizing hormone, prolactin, and progesterone serum levels interfering with the regression and apoptosis in rat corpus luteum. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120701 |
| Regulation of the surface expression of α4β2δ GABAA receptors by high efficacy states. | Brain research 20120629 |
| Neurosteroid biosynthesis and action during cerebellar development. | Cerebellum (London, England) 20120601 |
| A mouse kindling model of perimenstrual catamenial epilepsy. | The Journal of pharmacology and experimental therapeutics 20120601 |
| Neurosteroid binding to the amino terminal and glutamate binding domains of ionotropic glutamate receptors. | Steroids 20120601 |
| Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice. | The journal of pain : official journal of the American Pain Society 20120601 |
| The influence of social subordinate housing on the withdrawal effects from progesterone and estradiol in male rats. | General and comparative endocrinology 20120515 |
| Novel steroid inhibitors of glucose 6-phosphate dehydrogenase. | Journal of medicinal chemistry 20120510 |
| Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease. | Current Alzheimer research 20120501 |
| Effects of koumine, an alkaloid of Gelsemium elegans Benth., on inflammatory and neuropathic pain models and possible mechanism with allopregnanolone. | Pharmacology, biochemistry, and behavior 20120501 |
| Neurosteroid allopregnanolone regulates EAAC1-mediated glutamate uptake and triggers actin changes in Schwann cells. | Journal of cellular physiology 20120401 |
| Allopregnanolone infused into the dorsal (CA1) hippocampus increases prepulse inhibition of startle response in Wistar rats. | Psychoneuroendocrinology 20120401 |
| Allopregnanolone and induction of endogenous opioid inhibition of oxytocin responses to immune stress in pregnant rats. | Journal of neuroendocrinology 20120401 |
| Allopregnanolone potentiates the glutamate-mediated seizures induced by 4-aminopyridine in rat hippocampus in vivo. | Neurochemical research 20120301 |
| Quantitative analyses of antagonism: combinations of midazolam and either flunitrazepam or pregnanolone in rhesus monkeys discriminating midazolam. | The Journal of pharmacology and experimental therapeutics 20120301 |
| Allopregnanolone prevents memory impairment: effect on mRNA expression and enzymatic activity of hippocampal 3-α hydroxysteroid oxide-reductase. | Brain research bulletin 20120210 |
| Neurosteroid analogues. 17. Inverted binding orientations of androsterone enantiomers at the steroid potentiation site on γ-aminobutyric acid type A receptors. | Journal of medicinal chemistry 20120209 |
| Flavan-3-ol esters: new agents for exploring modulatory sites on GABA(A) receptors. | British journal of pharmacology 20120201 |
| Allopregnanolone prevents dieldrin-induced NMDA receptor internalization and neurotoxicity by preserving GABA(A) receptor function. | Endocrinology 20120201 |
| Synthesis of deuterium labeled NMDA receptor inhibitor - 20-Oxo-5β-[9,12,12-(2)H(3)]pregnan-3α-yl-L-glutamyl 1-ester. | Steroids 20120201 |
| A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: a mass spectrometric analysis. | Electrophoresis 20120201 |
| Allopregnanolone infusion induced neurobehavioural alterations in a neonatal foal: is this a clue to the pathogenesis of neonatal maladjustment syndrome? | Equine veterinary journal. Supplement 20120201 |
| Effect of maternal administration of allopregnanolone before birth asphyxia on neonatal hippocampal function in the spiny mouse. | Brain research 20120118 |
| Type 1 5α-reductase may be required for estrous cycle changes in affective behaviors of female mice. | Behavioural brain research 20120115 |
| Investigation of the mechanisms of progesterone protection following oxygen-glucose deprivation in organotypic hippocampal slice cultures. | Neuroscience letters 20120106 |
| Reinstatement of methamphetamine seeking in male and female rats treated with modafinil and allopregnanolone. | Drug and alcohol dependence 20120101 |
| Implication of allopregnanolone in the antinociceptive effect of N-palmitoylethanolamide in acute or persistent pain. | Pain 20120101 |
| Up-regulation of neurosteroid biosynthesis as a pharmacological strategy to improve behavioural deficits in a putative mouse model of post-traumatic stress disorder. | Journal of neuroendocrinology 20120101 |
| A thickening network of lipids. | Pain 20120101 |
| Progesterone and allopregnanolone exacerbate hypoxic-ischemic brain injury in immature rats. | Experimental neurology 20120101 |
| Assessment of estrus cyclicity in the Asian elephant (Elephas maximus) by measurement of fecal progesterone metabolite 5α-P-3OH, using a non-invasive assay. | General and comparative endocrinology 20120101 |
| Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats. | Neuropsychobiology 20120101 |
| The neurosteroids, allopregnanolone and progesterone, induce autophagy in cultured astrocytes. | Neurochemistry international 20120101 |
| Chronic allopregnanolone treatment accelerates Alzheimer's disease development in AβPP(Swe)PSEN1(ΔE9) mice. | Journal of Alzheimer's disease : JAD 20120101 |
| Neurosteroid influences on sensitivity to ethanol. | Frontiers in endocrinology 20120101 |
| Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). | PloS one 20120101 |
| The involvement of the neurosteroid allopregnanolone in the antihyperalgesic effect of paroxetine in a rat model of neuropathic pain. | Neuroreport 20111221 |
| Allopregnanolone, a GABAA receptor agonist, decreases gonadotropin levels in women. A preliminary study. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20111201 |
| Chronic administration of the anabolic androgenic steroid nandrolone alters neurosteroid action at the sigma-1 receptor but not at the sigma-2 or NMDA receptors. | Neuropharmacology 20111201 |
| Clinical and metabolic findings in a 6-year-old boy with a Leydig cell tumour. | Acta paediatrica (Oslo, Norway : 1992) 20111201 |
| Role of the neurosteroid allopregnanolone in the hyperalgesic behavior induced by painful nerve injury in rats. | Journal of anesthesia 20111201 |
| Localization of brain 5α-reductase messenger RNA in mice selectively bred for high chronic alcohol withdrawal severity. | Alcohol (Fayetteville, N.Y.) 20111201 |
| Modulation of presynaptic GABA(A) receptors by endogenous neurosteroids. | British journal of pharmacology 20111101 |
| Alteration of ethanol drinking in mice via modulation of the GABA(A) receptor with ganaxolone, finasteride, and gaboxadol. | Alcoholism, clinical and experimental research 20111101 |
| Novel substrates for, and sources of, progestogens for reproduction. | Journal of neuroendocrinology 20111101 |
| Inhibition of 5α-reductase activity in late pregnancy decreases gestational length and fecundity and impairs object memory and central progestogen milieu of juvenile rat offspring. | Journal of neuroendocrinology 20111101 |
| Immune stress in late pregnant rats decreases length of gestation and fecundity, and alters later cognitive and affective behaviour of surviving pre-adolescent offspring. | Stress (Amsterdam, Netherlands) 20111101 |
| Infusions of allopregnanolone into the hippocampus and amygdala, but not into the nucleus accumbens and medial prefrontal cortex, produce antidepressant effects on the learned helplessness rats. | Hippocampus 20111001 |
| Changes in functioning of mesolimbic incentive processing circuits during the premenstrual phase. | Social cognitive and affective neuroscience 20111001 |
| Neurosteroids infusion into the CA1 hippocampal region on exploration, anxiety-like behaviour and aversive learning. | Behavioural brain research 20110912 |
| Differential modulation of the glutamate-nitric oxide-cyclic GMP pathway by distinct neurosteroids in cerebellum in vivo. | Neuroscience 20110908 |
| Neuropharmacological properties of neurons derived from human stem cells. | Neurochemistry international 20110901 |
| AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder. | Journal of affective disorders 20110901 |
| Sex difference in sensitivity to allopregnanolone neuroprotection in mice correlates with effect on spontaneous inhibitory post synaptic currents. | Neuropharmacology 20110901 |
| Effects of pregnanolone and flunitrazepam on the retention of response sequences in rats. | Pharmacology, biochemistry, and behavior 20110901 |
| Impaired neurosteroid synthesis in multiple sclerosis. | Brain : a journal of neurology 20110901 |
| Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110803 |
| Hormonal therapy for epilepsy. | Current neurology and neuroscience reports 20110801 |
| Allopregnanolone induces LHRH and glutamate release through NMDA receptor modulation. | Endocrine 20110801 |
| Effect of acute ethanol and acute allopregnanolone on spatial memory in adolescent and adult rats. | Alcohol (Fayetteville, N.Y.) 20110801 |
| Occupation of either site for the neurosteroid allopregnanolone potentiates the opening of the GABAA receptor induced from either transmitter binding site. | Molecular pharmacology 20110701 |
| Palmitoylethanolamide stimulation induces allopregnanolone synthesis in C6 Cells and primary astrocytes: involvement of peroxisome-proliferator activated receptor-α. | Journal of neuroendocrinology 20110701 |
| Mechanisms responsible for progesterone's protection against lordosis-inhibiting effects of restraint II. Role of progesterone metabolites. | Hormones and behavior 20110701 |
| S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice. | Neuropharmacology 20110601 |
| Isolation rearing-induced reduction of brain 5α-reductase expression: relevance to dopaminergic impairments. | Neuropharmacology 20110601 |
| Anticonflict and reinforcing effects of triazolam + pregnanolone combinations in rhesus monkeys. | The Journal of pharmacology and experimental therapeutics 20110601 |
| Neurosteroid modulation of benzodiazepine-sensitive GABAA tonic inhibition in supraoptic magnocellular neurons. | American journal of physiology. Regulatory, integrative and comparative physiology 20110601 |
| Inhibitors of human 20α-hydroxysteroid dehydrogenase (AKR1C1). | The Journal of steroid biochemistry and molecular biology 20110501 |
| Effects of voluntary ethanol consumption on emotional state and stress responsiveness in socially isolated rats. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20110501 |
| [Effects of neuroactive steroid allopregnanolone on the damage of cortical neurons]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110501 |
| II. Cognitive performance of middle-aged female rats is influenced by capacity to metabolize progesterone in the prefrontal cortex and hippocampus. | Brain research 20110316 |
| I. Levels of 5α-reduced progesterone metabolite in the midbrain account for variability in reproductive behavior of middle-aged female rats. | Brain research 20110316 |
| Divergent mechanisms for trophic actions of estrogens in the brain and peripheral tissues. | Brain research 20110316 |
| Progesterone reduces depressive behavior of young ovariectomized, aged progestin receptor knockout, and aged wild type mice in the tail suspension test. | Journal of psychopharmacology (Oxford, England) 20110301 |
| Comparing the discriminative stimuli produced by either the neuroactive steroid pregnanolone or the benzodiazepine midazolam in rats. | Psychopharmacology 20110301 |
| Sex-dependent effect of a low neurosteroid environment and intrauterine growth restriction on foetal guinea pig brain development. | The Journal of endocrinology 20110301 |
| Environmental enrichment alters gene expression of steroidogenic enzymes in the rat hippocampus. | General and comparative endocrinology 20110301 |
| Multiple effects of allopregnanolone on GABAergic responses in single hippocampal CA3 pyramidal neurons. | European journal of pharmacology 20110210 |
| Progesterone, administered before kainic acid, prevents decrements in cognitive performance in the Morris Water Maze. | Developmental neurobiology 20110201 |
| Interaction between early postnatal neurosteroid manipulations and adult infusion of neurosteroids into CA1 hippocampal region on the open field behaviour. | Behavioural brain research 20110120 |
| Differential effects of two major neurosteroids on cerebellar and cortical GABA(A) receptor binding and function. | European journal of pharmacology 20110110 |
| Allopregnanolone levels decrease after gonadotropin-releasing hormone analog stimulation test in girls with central precocious puberty. | Journal of endocrinological investigation 20110101 |
| Allopregnanolone and suppressed hypothalamo-pituitary-adrenal axis stress responses in late pregnancy in the rat. | Stress (Amsterdam, Netherlands) 20110101 |
| Effects of neurosteroid actions at N-methyl-D-aspartate and GABA A receptors in the midbrain ventral tegmental area for anxiety-like and mating behavior of female rats. | Psychopharmacology 20110101 |
| Tolerance to allopregnanolone with focus on the GABA-A receptor. | British journal of pharmacology 20110101 |
| Circulating levels of allopregnanolone, a neuroactive steroid, and leptin during treatment with valproic acid in children with epilepsy. | Neuroendocrinology 20110101 |
| Juvenile offspring of rats exposed to restraint stress in late gestation have impaired cognitive performance and dysregulated progestogen formation. | Stress (Amsterdam, Netherlands) 20110101 |
| Progesterone turnover to its 5α-reduced metabolites in the ventral tegmental area of the midbrain is essential for initiating social and affective behavior and progesterone metabolism in female rats. | Journal of endocrinological investigation 20110101 |
| Allopregnanolone prevents and suppresses oxaliplatin-evoked painful neuropathy: multi-parametric assessment and direct evidence. | Pain 20110101 |
| Preclinical pharmacokinetics, dose proportionality, gender difference and protein binding study of 16-dehydropregnenolone, an antihyperlipidemic agent, in rats. | The Journal of pharmacy and pharmacology 20110101 |
| Neurosteroids for a successful pregnancy. | Stress (Amsterdam, Netherlands) 20110101 |
| Neuroprotective effects of progesterone and allopregnanolone on long-term cognitive outcome after global cerebral ischemia. | Restorative neurology and neuroscience 20110101 |
| Voluntary Ethanol Consumption Induced by Social Isolation Reverses the Increase of α(4)/δ GABA(A) Receptor Gene Expression and Function in the Hippocampus of C57BL/6J Mice. | Frontiers in neuroscience 20110101 |
| Cellular and behavioural effects of a new steroidal inhibitor of the N-methyl-d-aspartate receptor 3α5β-pregnanolone glutamate. | Neuropharmacology 20110101 |
| Gestational exposure to variable stressors produces decrements in cognitive and neural development of juvenile male and female rats. | Current topics in medicinal chemistry 20110101 |
| Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease. | PloS one 20110101 |
| Corneal alterations during combined therapy with cyclodextrin/allopregnanolone and miglustat in a knock-out mouse model of NPC1 disease. | PloS one 20110101 |
| Effects and Mechanisms of 3α,5α,-THP on Emotion, Motivation, and Reward Functions Involving Pregnane Xenobiotic Receptor. | Frontiers in neuroscience 20110101 |
| Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20101215 |
| Pregnenolone and ganaxolone reduce operant ethanol self-administration in alcohol-preferring p rats. | Alcoholism, clinical and experimental research 20101201 |
| Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats. | Biological psychiatry 20101115 |
| The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain. | Glia 20101115 |
| Fecal steroid metabolites and reproductive monitoring in a female Tsushima leopard cat (Prionailurus bengalensis euptilurus). | Theriogenology 20101101 |
| Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals. | Neurobiology of disease 20101101 |
| Progesterone and allopregnanolone attenuate blood-brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases. | Experimental neurology 20101101 |
| Allosteric modulation of the NMDA receptor by neurosteroids in rat brain and the impact of long term morphine administration. | Biochemical and biophysical research communications 20101029 |
| Neurosteroid withdrawal regulates GABA-A receptor α4-subunit expression and seizure susceptibility by activation of progesterone receptor-independent early growth response factor-3 pathway. | Neuroscience 20101027 |
| Chronic ethanol exposure produces tolerance to elevations in neuroactive steroids: mechanisms and reversal by exogenous ACTH. | Journal of neurochemistry 20101001 |
| Differential effects of allopregnanolone on the escalation of cocaine self-administration and sucrose intake in female rats. | Psychopharmacology 20101001 |
| Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001. | Pain medicine (Malden, Mass.) 20101001 |
| Adaptation to extreme stress: post-traumatic stress disorder, neuropeptide Y and metabolic syndrome. | Experimental biology and medicine (Maywood, N.J.) 20101001 |
| Metformin administration restores allopregnanolone response to adrenocorticotropic hormone (ACTH) stimulation in overweight hyperinsulinemic patients with PCOS. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100901 |
| In a mouse model relevant for post-traumatic stress disorder, selective brain steroidogenic stimulants (SBSS) improve behavioral deficits by normalizing allopregnanolone biosynthesis. | Behavioural pharmacology 20100901 |
| Fluoxetine-induced decrements in sexual responses of female rats and hamsters are reversed by 3α,5α-THP. | The journal of sexual medicine 20100801 |
| Allopregnanolone levels are reduced in temporal cortex in patients with Alzheimer's disease compared to cognitively intact control subjects. | Biochimica et biophysica acta 20100801 |
| Naltrexone selectively elevates GABAergic neuroactive steroid levels in heavy drinkers with the Asp40 allele of the OPRM1 gene: a pilot investigation. | Alcoholism, clinical and experimental research 20100801 |
| A role for Src kinase in progestin facilitation of estrous behavior in estradiol-primed female rats. | Hormones and behavior 20100701 |
| Acute neurosteroids inhibit the spinal reflex potentiation via GABAergic neurotransmission. | American journal of physiology. Renal physiology 20100701 |
| Synthesis and GABAA receptor activity of A-homo analogues of neuroactive steroids. | European journal of medicinal chemistry 20100701 |
| New therapeutic approaches for epilepsies, focusing on reorganization of the GABAA receptor subunits by neurosteroids. | Epilepsia 20100701 |
| Neonatal exposure to estradiol in rats influences neuroactive steroid concentrations, GABAA receptor expression, and behavioral sensitivity to anxiolytic drugs. | Journal of neurochemistry 20100601 |
| Mechanisms involved in the modulation of astroglial resistance to oxidative stress induced by activated microglia: antioxidative systems, peroxide elimination, radical generation, lipid peroxidation. | Neurotoxicity research 20100501 |
| Alterations in neonatal neurosteroids affect exploration during adolescence and prepulse inhibition in adulthood. | Psychoneuroendocrinology 20100501 |
| Treatment with progesterone after focal cerebral ischemia suppresses proliferation of progenitor cells but enhances survival of newborn neurons in adult male mice. | Neuropharmacology 20100501 |
| Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model. | Epilepsy research 20100501 |
| Do 5-alpha reductase inhibitors influence the severity of brain injury in men after a stroke? | Medical hypotheses 20100501 |
| Prediction of estrus cyclicity in Asian elephants (Elephas maximus) through estimation of fecal progesterone metabolite: development of an enzyme-linked immuno-sorbent assay. | Theriogenology 20100501 |
| Endogenous neurosteroid synthesis modulates seizure frequency. | Annals of neurology 20100501 |
| Low doses of cocaine decrease, and high doses increase, anxiety-like behavior and brain progestogen levels among intact rats. | Hormones and behavior 20100401 |
| A critical role for alpha4betadelta GABAA receptors in shaping learning deficits at puberty in mice. | Science (New York, N.Y.) 20100319 |
| Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice. | Neuroscience 20100310 |
| Neuropeptide Y Y1 receptors in the central nucleus of amygdala mediate the anxiolytic-like effect of allopregnanolone in mice: Behavioral and immunocytochemical evidences. | Brain research 20100308 |
| A residue in loop 9 of the beta2-subunit stabilizes the closed state of the GABAA receptor. | The Journal of biological chemistry 20100305 |
| Palmitoylethanolamide modulates pentobarbital-evoked hypnotic effect in mice: involvement of allopregnanolone biosynthesis. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20100301 |
| Sex differences in the effects of allopregnanolone on yohimbine-induced reinstatement of cocaine seeking in rats. | Drug and alcohol dependence 20100301 |
| Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans. | Alcoholism, clinical and experimental research 20100301 |
| The effect of betamethasone treatment on neuroactive steroid synthesis in a foetal Guinea pig model of growth restriction. | Journal of neuroendocrinology 20100301 |
| Effects of gestational allopregnanolone administration in rats bred for high affective behavior. | Physiology & behavior 20100209 |
| Neuroactive steroids after estrogen exposure in depressed postmenopausal women treated with sertraline and asymptomatic postmenopausal women. | Archives of women's mental health 20100201 |
| GABA synthesis in Schwann cells is induced by the neuroactive steroid allopregnanolone. | Journal of neurochemistry 20100201 |
| Dopamine is involved in the antidepressant-like effect of allopregnanolone in the forced swimming test in female rats. | Behavioural pharmacology 20100201 |
| Ethanol induction of steroidogenesis in rat adrenal and brain is dependent upon pituitary ACTH release and de novo adrenal StAR synthesis. | Journal of neurochemistry 20100201 |
| Premenstrual dysphoric disorder: out of the appendix. | Archives of women's mental health 20100201 |
| Two new terpenoids from Trichilia quadrijuga (Meliaceae). | Natural product communications 20100201 |
| Anticonvulsant doses of ganaxolone do not compromise motor performance in immature rats. | Neuroscience letters 20100129 |
| Anticonvulsant action of a new analogue of allopregnanolone in immature rats. | Physiological research 20100101 |
| Manipulation of GABAergic steroids: Sex differences in the effects on alcohol drinking- and withdrawal-related behaviors. | Hormones and behavior 20100101 |
| Neural mechanisms underlying changes in stress-sensitivity across the menstrual cycle. | Psychoneuroendocrinology 20100101 |
| Acute experimental autoimmune encephalomyelitis induces sex dimorphic changes in neuroactive steroid levels. | Neurochemistry international 20100101 |
| Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice. | Pharmacology, biochemistry, and behavior 20100101 |
| Surgical management of placenta accreta: a cohort series and suggested approach. | American journal of obstetrics and gynecology 20100101 |
| Neurosteroids: endogenous role in the human brain and therapeutic potentials. | Progress in brain research 20100101 |
| Allopregnanolone effects on astrogliosis induced by hypoxia in organotypic cultures of striatum, hippocampus, and neocortex. | Brain research 20091215 |
| Puberty, steroids and GABA(A) receptor plasticity. | Psychoneuroendocrinology 20091201 |
| Plasticity and function of extrasynaptic GABA(A) receptors during pregnancy and after delivery. | Psychoneuroendocrinology 20091201 |
| Neurosteroids' effects and mechanisms for social, cognitive, emotional, and physical functions. | Psychoneuroendocrinology 20091201 |
| Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5alpha-reductase enzyme activity and expression. | Alcoholism, clinical and experimental research 20091201 |
| Plasticity of the alpha4betadelta GABAA receptor. | Biochemical Society transactions 20091201 |
| Progesterone and allopregnanolone enhance the miniature synaptic release of glycine in the rat hypoglossal nucleus. | The European journal of neuroscience 20091201 |
| The effects of acute and chronic ethanol exposure on presynaptic and postsynaptic gamma-aminobutyric acid (GABA) neurotransmission in cultured cortical and hippocampal neurons. | Alcohol (Fayetteville, N.Y.) 20091201 |
| Alpha-methyltyrosine inhibits formation of reactive oxygen species and diminishes apoptosis in PC12 cells. | Brain research 20091103 |
| The role of neuroactive steroids in ethanol/stress interactions: proceedings of symposium VII at the Volterra conference on alcohol and stress, May 2008. | Alcohol (Fayetteville, N.Y.) 20091101 |
| Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain. | Neuroscience 20091020 |
| Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury. | Journal of medicinal chemistry 20091008 |
| Neonatal allopregnanolone increases novelty-directed locomotion and disrupts behavioural responses to GABA(A) receptor modulators in adulthood. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20091001 |
| Neurosteroids modulate compulsive and persistent behavior in rodents: implications for obsessive-compulsive disorder. | Progress in neuro-psychopharmacology & biological psychiatry 20091001 |
| Olanzapine plus 17-beta estradiol produce antidepressant-like actions in rats forced to swim. | Pharmacology, biochemistry, and behavior 20091001 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Allopregnanolone microinjected into the lateral septum or dorsal hippocampus reduces immobility in the forced swim test: participation of the GABAA receptor. | Behavioural pharmacology 20091001 |
| Synthesis of fluorinated brassinosteroids based on alkene cross-metathesis and preliminary biological assessment. | Journal of medicinal chemistry 20090924 |
| Synthesis and GABA(A) receptor activity of 2,19-sulfamoyl analogues of allopregnanolone. | Bioorganic & medicinal chemistry 20090915 |
| Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone. | Journal of cellular and molecular medicine 20090901 |
| Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABAA modulators. | Psychoneuroendocrinology 20090901 |
| 17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities. | European journal of pharmacology 20090901 |
| Trilostane exerts antidepressive effects among wild-type, but not estrogen receptor [beta] knockout mice. | Neuroreport 20090805 |
| Evaluation of putative inhibitors of mitochondrial permeability transition for brain disorders--specificity vs. toxicity. | Experimental neurology 20090801 |
| Central modifications of allopregnanolone and beta-endorphin following subcutaneous administration of Nestorone. | The Journal of steroid biochemistry and molecular biology 20090801 |
| Progesterone receptor A (PRA) and PRB-independent effects of progesterone on gonadotropin-releasing hormone release. | Endocrinology 20090801 |
| Structure-activity relationship of etomidate derivatives at the GABA(A) receptor: Comparison with binding to 11beta-hydroxylase. | Bioorganic & medicinal chemistry letters 20090801 |
| The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction. | Journal of neurophysiology 20090801 |
| Allopregnanolone levels before and after selective serotonin reuptake inhibitor treatment of premenstrual symptoms. | Journal of clinical psychopharmacology 20090801 |
| Excitability changes related to GABAA receptor plasticity during pregnancy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090729 |
| Selective changes in sensitivity to benzodiazepines, and not other positive GABA(A) modulators, in rats receiving flunitrazepam chronically. | Psychopharmacology 20090701 |
| Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090701 |
| Effects of pregnanolone and dehydroepiandrosterone on ethanol intake in rats administered ethanol or saline during adolescence. | Alcoholism, clinical and experimental research 20090701 |
| Discriminative stimulus effects of ethanol, pregnanolone, and dehydroepiandrosterone (DHEA) in rats administered ethanol or saline as adolescents. | Pharmacology, biochemistry, and behavior 20090701 |
| Neurosteroids differentially modulate P2X ATP-gated channels through non-genomic interactions. | Journal of neurochemistry 20090701 |
| Selective effect of chlormadinone acetate on brain allopregnanolone and opioids content. | Contraception 20090701 |
| Biphasic effects of neonatal allopregnanolone on striatal dopamine metabolism. | Neuroreport 20090617 |
| NMDA potentiation by visible light in the presence of a fluorescent neurosteroid analogue. | The Journal of physiology 20090615 |
| Allopregnanolone has no effect on startle response and prepulse inhibition of startle response in patients with premenstrual dysphoric disorder or healthy controls. | Pharmacology, biochemistry, and behavior 20090601 |
| Activation and modulation of concatemeric GABA-A receptors expressed in human embryonic kidney cells. | Molecular pharmacology 20090601 |
| Pregnanolone sulfate promotes desensitization of activated NMDA receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527 |
| Central opioid inhibition of neuroendocrine stress responses in pregnancy in the rat is induced by the neurosteroid allopregnanolone. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090520 |
| Allopregnanolone treatment delays cholesterol accumulation and reduces autophagic/lysosomal dysfunction and inflammation in Npc1-/- mouse brain. | Brain research 20090513 |
| Peripheral-type benzodiazepine receptor antagonist is effective in relieving neuropathic pain in mice. | Journal of pharmacological sciences 20090501 |
| Enhanced fear responses in mice treated with anabolic androgenic steroids. | Neuroreport 20090422 |
| Progestogens and brain: an update. | Maturitas 20090420 |
| Allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one) derivatives with a polar chain in position 16alpha: synthesis and activity. | Journal of medicinal chemistry 20090409 |
| Neurosteroid replacement therapy for catamenial epilepsy. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20090401 |
| Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism for better neuroprotective effects of allopregnanolone over progesterone. | Brain research 20090331 |
| Hormonal, cardiovascular, and subjective responses to acute stress in smokers. | Psychopharmacology 20090301 |
| Studies of pharmacokinetic and pharmacodynamic properties of isoallopregnanolone in healthy women. | Psychopharmacology 20090301 |
| Effects of allopregnanolone on the reinstatement of cocaine-seeking behavior in male and female rats. | Psychopharmacology 20090301 |
| Kinetic analysis of voltage-dependent potentiation and block of the glycine alpha 3 receptor by a neuroactive steroid analogue. | The Journal of physiology 20090301 |
| Measurement of ring A-reduced progesterone metabolites by enzyme-linked immunoassay with colorimetric detection: baseline levels of six metabolites, including pregnanolone, in male rat plasma. | Analytical chemistry 20090201 |
| SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake. | Current opinion in pharmacology 20090201 |
| Conserved site for neurosteroid modulation of GABA A receptors. | Neuropharmacology 20090101 |
| Increasing 3alpha,5alpha-THP following inhibition of neurosteroid biosynthesis in the ventral tegmental area reinstates anti-anxiety, social, and sexual behavior of naturally receptive rats. | Reproduction (Cambridge, England) 20090101 |
| Progesterone withdrawal-evoked plasticity of neural function in the female periaqueductal grey matter. | Neural plasticity 20090101 |
| Expression levels of the alpha4 subunit of the GABA(A) receptor in differentiated neuroblastoma cells are correlated with GABA-gated current. | Neuropharmacology 20090101 |
| Brain-region responsiveness to DT56a (Femarelle) administration on allopregnanolone and opioid content in ovariectomized rats. | Menopause (New York, N.Y.) 20090101 |
| Role of progesterone receptor isoforms in female sexual behavior induced by progestins in rats. | Neuroendocrinology 20090101 |
| GABA(A) receptor function and gene expression during pregnancy and postpartum. | International review of neurobiology 20090101 |
| Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression. | PloS one 20090101 |
| A new cytotoxic pregnanone from Calotropis gigantea. | Molecules (Basel, Switzerland) 20081204 |
| The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice. | Brain research 20081203 |
| Reinstatement of ethanol and sucrose seeking by the neurosteroid allopregnanolone in C57BL/6 mice. | Psychopharmacology 20081201 |
| Sexually dimorphic effects of testosterone administration on brain allopregnanolone in gonadectomized rats. | The journal of sexual medicine 20081201 |
| Progesterone and its metabolite allopregnanolone differentially regulate hemostatic proteins after traumatic brain injury. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20081101 |
| Ischemic insult to cerebellar Purkinje cells causes diminished GABAA receptor function and allopregnanolone neuroprotection is associated with GABAA receptor stabilization. | Journal of neurochemistry 20081101 |
| Possible GABAergic modulation in the protective effect of allopregnanolone on sleep deprivation-induced anxiety-like behavior and oxidative damage in mice. | Methods and findings in experimental and clinical pharmacology 20081101 |
| Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms. | Pain 20081031 |
| Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice. | Neurochemical research 20081001 |
| Role of acetaldehyde in ethanol-induced elevation of the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in rats. | Alcoholism, clinical and experimental research 20081001 |
| Persistence of tolerance to the anaesthetic effect of allopregnanolone in male rats. | European journal of pharmacology 20080911 |
| Ethanol intake patterns in female mice: influence of allopregnanolone and the inhibition of its synthesis. | Drug and alcohol dependence 20080901 |
| MRI detects therapeutic effects in weanling Niemann-Pick type C mice. | Journal of neuroscience research 20080901 |
| Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids. | Molecular pharmacology 20080901 |
| Neuroactive steroids and GABAA receptor plasticity in the brain of the WAG/Rij rat, a model of absence epilepsy. | Journal of neurochemistry 20080901 |
| Studies on neurosteroids XXV. Influence of a 5alpha-reductase inhibitor, finasteride, on rat brain neurosteroid levels and metabolism. | Biological & pharmaceutical bulletin 20080901 |
| Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901 |
| Antinociceptive profile of ring A-reduced progesterone metabolites in the formalin test. | Pain 20080831 |
| Menthol shares general anesthetic activity and sites of action on the GABA(A) receptor with the intravenous agent, propofol. | European journal of pharmacology 20080820 |
| Sex steroids effects on the content of GAD, TH, GABA(A), and glutamate receptors in the olfactory bulb of the male rat. | Neurochemical research 20080801 |
| Indomethacin improves locomotor deficit and reduces brain concentrations of neuroinhibitory steroids in rats following portacaval anastomosis. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080801 |
| Allopregnanolone impairs episodic memory in healthy women. | Psychopharmacology 20080801 |
| Inhibition of 5alpha-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice. | Alcoholism, clinical and experimental research 20080801 |
| Neurosteroids allosterically modulate the ion pore of the NMDA receptor consisting of NR1/NR2B but not NR1/NR2A. | Biochemical and biophysical research communications 20080725 |
| Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration. | Neuroscience 20080717 |
| GABA in the female brain -- oestrous cycle-related changes in GABAergic function in the periaqueductal grey matter. | Pharmacology, biochemistry, and behavior 20080701 |
| Antidepressant effect and changes of GABAA receptor gamma2 subunit mRNA after hippocampal administration of allopregnanolone in rats. | Journal of psychopharmacology (Oxford, England) 20080701 |
| Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy. | Epilepsia 20080701 |
| Olanzapine counteracts stress-induced anxiety-like behavior in rats. | Neuroscience letters 20080620 |
| Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice. | The international journal of neuropsychopharmacology 20080601 |
| Neuroactive steroids and fatigue severity in patients with primary biliary cirrhosis and hepatitis C. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080601 |
| Dydrogesterone increases allopregnanolone in selected brain areas and in serum of female rats. | Fertility and sterility 20080501 |
| Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells. | Journal of neuroscience research 20080501 |
| Investigation of the anticonvulsive effect of acute immobilization stress in anxious Balb/cByJ mice using GABA A-related mechanistic probes. | Psychopharmacology 20080501 |
| Progesterone and allopregnanolone are induced by cocaine in serum and brain tissues of male and female rats. | Pharmacology, biochemistry, and behavior 20080501 |
| Overlapping, but not identical, discriminative stimulus effects of the neuroactive steroid pregnanolone and ethanol. | Pharmacology, biochemistry, and behavior 20080501 |
| Effects of nomegestrol acetate administration on central and peripheral beta-endorphin and allopregnanolone in ovx rats. | The Journal of steroid biochemistry and molecular biology 20080501 |
| 5Beta,6beta-epoxy-17-oxoandrostan-3beta-yl acetate and 5beta,6beta-epoxy-20-oxopregnan-3beta-yl acetate. | Acta crystallographica. Section C, Crystal structure communications 20080501 |
| Regulation of neurosteroid allopregnanolone biosynthesis in the rat spinal cord by glycine and the alkaloidal analogs strychnine and gelsemine. | Neuroscience 20080422 |
| One-year therapy with 10mg/day DHEA alone or in combination with HRT in postmenopausal women: effects on hormonal milieu. | Maturitas 20080420 |
| Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice. | Pharmacology, biochemistry, and behavior 20080401 |
| Synthesis and GABA(A) receptor activity of oxygen-bridged neurosteroid analogs. | Bioorganic & medicinal chemistry 20080401 |
| Endogenous and synthetic neurosteroids in treatment of Niemann-Pick Type C disease. | Brain research reviews 20080301 |
| Regenerative potential of allopregnanolone. | Brain research reviews 20080301 |
| Genetic variations and treatments that affect the lifespan of the NPC1 mouse. | Journal of lipid research 20080301 |
| Neuroactive Steroid Levels in a transgenic rat model of CMT1A Neuropathy. | Journal of molecular neuroscience : MN 20080301 |
| Effect of psychotropic drugs on the 21-hydroxylation of neurosteroids, progesterone and allopregnanolone, catalyzed by rat CYP2D4 and human CYP2D6 in the brain. | Biological & pharmaceutical bulletin 20080301 |
| Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABA(A) modulating neurosteroid. | Progress in neuro-psychopharmacology & biological psychiatry 20080215 |
| Effects of swim stress on mRNA and protein levels of steroid 5alpha-reductase isozymes in prefrontal cortex of adult male rats. | Neurochemistry international 20080201 |
| Modulatory effect of neurosteroids in haloperidol-induced vacuous chewing movements and related behaviors. | Psychopharmacology 20080201 |
| Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate. | British journal of pharmacology 20080201 |
| Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice. | Neuropharmacology 20080201 |
| Neurosteroid analogues. 12. Potent enhancement of GABA-mediated chloride currents at GABAA receptors by ent-androgens. | European journal of medicinal chemistry 20080101 |
| Neurosteroids in the fetus and neonate: potential protective role in compromised pregnancies. | Neurochemistry international 20080101 |
| Effects of progesterone administration and APPswe+PSEN1Deltae9 mutation for cognitive performance of mid-aged mice. | Neurobiology of learning and memory 20080101 |
| Etomidate and other non-barbiturates. | Handbook of experimental pharmacology 20080101 |
| Neurosteroids in the Purkinje cell: biosynthesis, mode of action and functional significance. | Molecular neurobiology 20080101 |
| Induction of Akt by endogenous neurosteroids and calcium sequestration in P19 derived neurons. | Neurotoxicity research 20080101 |
| Brain allopregnanolone in the fetal and postnatal rat in response to uteroplacental insufficiency. | Neuroendocrinology 20080101 |
| Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential. | BMC neuroscience 20080101 |
| Interaction of diazepam and swim stress. | Brain research 20071212 |
| Neurosteroid allopregnanolone mediates anxiolytic effect of etifoxine in rats. | Brain research 20071212 |
| The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy. | Metabolic brain disease 20071201 |
| Differential anesthetic activity of ketamine and the GABAergic neurosteroid allopregnanolone in mice lacking progesterone receptor A and B subtypes. | Methods and findings in experimental and clinical pharmacology 20071201 |
| Influence of epipregnanolone on the modulation of rapid tolerance to ethanol by neurosteroids. | Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20071201 |
| Regeneration in a degenerating brain: potential of allopregnanolone as a neuroregenerative agent. | Current Alzheimer research 20071201 |
| Diminished neurosteroid sensitivity of synaptic inhibition and altered location of the alpha4 subunit of GABA(A) receptors in an animal model of epilepsy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20071114 |
| Neurosteroid migration to intracellular compartments reduces steroid concentration in the membrane and diminishes GABA-A receptor potentiation. | The Journal of physiology 20071101 |
| [Neurological and psychiatric aspects of some endocrine diseases. The role of neurosteroids and neuroactive steroids]. | Orvosi hetilap 20071014 |
| Neurosteroid regulation of GABA(A) receptors: Focus on the alpha4 and delta subunits. | Pharmacology & therapeutics 20071001 |
| Inhibition of progesterone metabolism mimics the effect of progesterone withdrawal on forced swim test immobility. | Pharmacology, biochemistry, and behavior 20071001 |
| Clinical evaluation of ganaxolone in pediatric and adolescent patients with refractory epilepsy. | Epilepsia 20071001 |
| Neurosteroid regulation of central nervous system development. | Pharmacology & therapeutics 20071001 |
| Allopregnanolone serum concentrations and neurosteroid sensitivity during withdrawal from postmenopausal hormone therapy. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20071001 |
| Relationships of circulating pregnanolone isomers and their polar conjugates to the status of sex, menstrual cycle, and pregnancy. | The Journal of endocrinology 20071001 |
| Neurosteroids reduce inflammation after TBI through CD55 induction. | Neuroscience letters 20070925 |
| GABAA and glycine receptor-mediated transmission in rat lamina II neurones: relevance to the analgesic actions of neuroactive steroids. | The Journal of physiology 20070915 |
| The relationship of allopregnanolone immunoreactivity and HPA-axis measures to experimental pain sensitivity: Evidence for ethnic differences. | Pain 20070901 |
| Estrogens and progestins enhance spatial learning of intact and ovariectomized rats in the object placement task. | Neurobiology of learning and memory 20070901 |
| Allopregnanolone modulates striatal dopamingergic activity of rats under different gonadal hormones conditions. | Neurological research 20070901 |
| The anxiolytic-like effects of allopregnanolone vary as a function of intracerebral microinfusion site: the amygdala, medial prefrontal cortex, or hippocampus. | Behavioural pharmacology 20070901 |
| Acute effects of neurosteroids in a rodent model of primary paroxysmal dystonia. | Hormones and behavior 20070801 |
| A 17beta-derivative of allopregnanolone is a neurosteroid antagonist at a cerebellar subpopulation of GABA A receptors with nanomolar affinity. | British journal of pharmacology 20070801 |
| Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats. | European journal of pharmacology 20070719 |
| Inhibition of evoked glutamate release by neurosteroid allopregnanolone via inhibition of L-type calcium channels in rat medial prefrontal cortex. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070701 |
| Effects of combination treatment with mood stabilizers and mirtazapine on plasma concentrations of neuroactive steroids in depressed patients. | Psychoneuroendocrinology 20070701 |
| Neurosteroid modulation of neuronal excitability and synaptic transmission in the rat medial vestibular nuclei. | The European journal of neuroscience 20070701 |
| Inhibition of neurosteroid synthesis increases asphyxia-induced brain injury in the late gestation fetal sheep. | Neuroscience 20070608 |
| Microbial transformation of 5alpha,6alpha-epoxy-3beta-hydroxy-16-pregnen-20-one by Trichoderma viride. | Steroids 20070601 |
| Effects of allopregnanolone on sedation in men, and in women on oral contraceptives. | Psychoneuroendocrinology 20070601 |
| A novel chemical delivery system comprising an ocular sustained release formulation of a 3alpha, 17alpha, 21-trihydroxy-5beta-pregnan-20-one-BIS-5-fluorouracil [correction of flourouracil] codrug. | Drug development and industrial pharmacy 20070601 |
| Allopregnanolone influences the consummatory processes that govern ethanol drinking in C57BL/6J mice. | Behavioural brain research 20070516 |
| Intrahippocampal allopregnanolone decreases voluntary chronic alcohol consumption in non-selected rats. | Progress in neuro-psychopharmacology & biological psychiatry 20070509 |
| Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys. | Psychopharmacology 20070501 |
| Allopregnanolone decrease with symptom improvement during placebo and gonadotropin-releasing hormone agonist treatment in women with severe premenstrual syndrome. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20070501 |
| The neuroactive steroids alphaxalone and pregnanolone increase the conductance of single GABAA channels in newborn rat hippocampal neurons. | The Journal of steroid biochemistry and molecular biology 20070401 |
| Anticonvulsant and anesthetic effects of a fluorescent neurosteroid analog activated by visible light. | Nature neuroscience 20070401 |
| Reversal of neurosteroid effects at alpha4beta2delta GABAA receptors triggers anxiety at puberty. | Nature neuroscience 20070401 |
| Cellular distribution of the GABAA receptor-modulating 3alpha-hydroxy, 5alpha-reduced pregnane steroids in the adult rat brain. | Journal of neuroendocrinology 20070401 |
| Neurosteroid modulation of GABAergic neurotransmission in the central amygdala: a role for NMDA receptors. | Neuroscience letters 20070326 |
| High basal serum allopregnanolone levels in overweight girls. | International journal of obesity (2005) 20070301 |
| Neuroprotective effects of steroid analogues on P19-N neurons. | Neurochemistry international 20070301 |
| Engaging in paced mating, but neither exploratory, anti-anxiety, nor social behavior, increases 5alpha-reduced progestin concentrations in midbrain, hippocampus, striatum, and cortex. | Reproduction (Cambridge, England) 20070301 |
| Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: a multimodal analysis. | Neuroscience 20070223 |
| Differential regulation of ionotropic glutamate receptors. | Biophysical journal 20070215 |
| Ethanol modulates the interaction of the endogenous neurosteroid allopregnanolone with the alpha1beta2gamma2L GABAA receptor. | Molecular pharmacology 20070201 |
| [A new aspect in the research on antiepileptic drugs]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070201 |
| The progesterone metabolite allopregnanolone potentiates GABA(A) receptor-mediated inhibition of 5-HT neuronal activity. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070115 |
| The anticonvulsant effects of allopregnanolone against amygdala-kindled seizures in female rats. | Neuroscience letters 20070110 |
| Steroid requirements for regulation of the alpha4 subunit of the GABA(A) receptor in an in vitro model. | Neuroscience letters 20070103 |
| Allopregnanolone reduces immobility in the forced swimming test and increases the firing rate of lateral septal neurons through actions on the GABAA receptor in the rat. | Journal of psychopharmacology (Oxford, England) 20070101 |
| Lack of enantiomeric specificity in the effects of anesthetic steroids on lipid bilayers. | Biochimica et biophysica acta 20070101 |
| In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
| Drospirenone increases central and peripheral beta-endorphin in ovariectomized female rats. | Menopause (New York, N.Y.) 20070101 |
| Ganaxolone. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101 |
| [Neurosteroids and their function]. | Casopis lekaru ceskych 20070101 |
| A new, non-SSRI mechanism of action for Prozac. | Current topics in medicinal chemistry 20070101 |
| Circulating levels of pregnanolone isomers during the third trimester of human pregnancy. | The Journal of steroid biochemistry and molecular biology 20070101 |
| Neuroactive steroids modulate HPA axis activity and cerebral brain-derived neurotrophic factor (BDNF) protein levels in adult male rats. | Psychoneuroendocrinology 20070101 |
| Pseudo-epileptic seizures in children are not associated with enhanced plasma level of allopregnanolone. | Pharmacological reports : PR 20070101 |
| The neurosteroid allopregnanolone is reduced in prefrontal cortex in Alzheimer's disease. | Biological psychiatry 20061215 |
| Progesterone and progestins: effects on brain, allopregnanolone and beta-endorphin. | The Journal of steroid biochemistry and molecular biology 20061201 |
| Infusions of 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) to the ventral tegmental area, but not the substantia nigra, enhance exploratory, anti-anxiety, social and sexual behaviours and concomitantly increase 3alpha,5alpha-THP concentrations in the hippocampus, diencephalon and cortex of ovariectomised oestrogen-primed rats. | Journal of neuroendocrinology 20061201 |
| Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites. | Nature 20061123 |
| Neurosteroid modulation of allopregnanolone and GABA effect on the GABA-A receptor. | Neuroscience 20061117 |
| The effect of gonadal hormones and gender on anxiety and emotional learning. | Hormones and behavior 20061101 |
| Oral progesterone decreases saccadic eye velocity and increases sedation in women. | Psychoneuroendocrinology 20061101 |
| Associations of histories of depression and PMDD diagnosis with allopregnanolone concentrations following the oral administration of micronized progesterone. | Psychoneuroendocrinology 20061101 |
| The anxiolytic effect of pregnancy in rats is reversed by finasteride. | Pharmacology, biochemistry, and behavior 20061101 |
| Neurosteroids as endogenous inhibitors of neuronal cell apoptosis in aging. | Annals of the New York Academy of Sciences 20061101 |
| Neurosteroids regulate mouse aggression induced by anabolic androgenic steroids. | Neuroreport 20061002 |
| Rapid inhibition of Ca2+ influx by neurosteroids in murine embryonic sensory neurones. | Cell calcium 20061001 |
| Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder. | Biological psychiatry 20061001 |
| Sensitivity to the locomotor-stimulant effects of ethanol and allopregnanolone: a quantitative trait locus study of common genetic influence. | Genes, brain, and behavior 20061001 |
| Effects of pregnanolone in rats discriminating cocaine. | Pharmacology, biochemistry, and behavior 20061001 |
| Progesterone and its metabolites 5-dihydroprogesterone and 5-3-tetrahydroprogesterone decrease LPS-induced NO release in the murine microglial cell line, BV-2. | Neuro endocrinology letters 20061001 |
| Mechanisms of modulation of pregnanolone on glycinergic response in cultured spinal dorsal horn neurons of rat. | Neuroscience 20060915 |
| Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma. | Neurochemistry international 20060901 |
| Anticonvulsant action of allopregnanolone in immature rats. | Epilepsy research 20060801 |
| Efficacy and the discriminative stimulus effects of negative GABAA modulators, or inverse agonists, in diazepam-treated rhesus monkeys. | The Journal of pharmacology and experimental therapeutics 20060801 |
| Serum profiles of free and conjugated neuroactive pregnanolone isomers in nonpregnant women of fertile age. | The Journal of clinical endocrinology and metabolism 20060801 |
| Allopregnanolone concentration and mood--a bimodal association in postmenopausal women treated with oral progesterone. | Psychopharmacology 20060801 |
| Tapered progesterone withdrawal promotes long-term recovery following brain trauma. | Experimental neurology 20060801 |
| Increased neuroactive steroid concentrations in women with bipolar disorder or major depressive disorder. | Journal of clinical psychopharmacology 20060801 |
| Plastic neuronal changes in GABA(A) receptor gene expression induced by progesterone metabolites: in vitro molecular and functional studies. | Pharmacology, biochemistry, and behavior 20060801 |
| Olanzapine and fluoxetine administration and coadministration increase rat hippocampal pregnenolone, allopregnanolone and peripheral deoxycorticosterone: implications for therapeutic actions. | Pharmacology, biochemistry, and behavior 20060801 |
| Neurosteroid analogues. 11. Alternative ring system scaffolds: gamma-aminobutyric acid receptor modulation and anesthetic actions of benz[f]indenes. | Journal of medicinal chemistry 20060727 |
| The anticonvulsant effects of progesterone and its metabolites on amygdala-kindled seizures in male rats. | Brain research 20060726 |
| Neurosteroid modulation of respiratory rhythm in rats during the perinatal period. | The Journal of physiology 20060715 |
| Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060701 |
| Social isolation-induced increase in alpha and delta subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABA receptor function. | Journal of neurochemistry 20060701 |
| Therapeutic potential of neurogenesis for prevention and recovery from Alzheimer's disease: allopregnanolone as a proof of concept neurogenic agent. | Current Alzheimer research 20060701 |
| Influence of ginsenoside Rb1 on brain neurosteroid during acute immobilization stress. | Archives of pharmacal research 20060701 |
| Ethnic differences in allopregnanolone concentrations in women during rest and following mental stress. | Psychophysiology 20060701 |
| Chronic intermittent ethanol exposure during adolescence reduces the effect of ethanol challenge on hippocampal allopregnanolone levels and Morris water maze task performance. | Alcohol (Fayetteville, N.Y.) 20060701 |
| Pharmacokinetics of progesterone and its metabolites allopregnanolone and pregnanolone after oral administration of low-dose progesterone. | Maturitas 20060620 |
| Lack of evidence of a role for the neurosteroid allopregnanolone in ethanol-induced reward and c-fos expression in DBA/2 mice. | Brain research 20060613 |
| Neurosteroids in nicotine and morphine dependence. | Psychopharmacology 20060601 |
| Neurosteroids, GABAA receptors, and ethanol dependence. | Psychopharmacology 20060601 |
| Pharmacokinetic and behavioral effects of allopregnanolone in healthy women. | Psychopharmacology 20060601 |
| Steroid withdrawal in the mouse results in anxiogenic effects of 3alpha,5beta-THP: a possible model of premenstrual dysphoric disorder. | Psychopharmacology 20060601 |
| 3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia. | Psychopharmacology 20060601 |
| Moderate doses of ethanol fail to increase plasma levels of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one-like immunoreactivity in healthy men and women. | Psychopharmacology 20060601 |
| Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action. | Psychopharmacology 20060601 |
| Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes. | Psychopharmacology 20060601 |
| An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons. | Neurochemistry international 20060601 |
| Early postnatal stimulation alters pregnane neurosteroids in the hippocampus. | Psychopharmacology 20060601 |
| Enantiomers of neuroactive steroids support a specific interaction with the GABA-C receptor as the mechanism of steroid action. | Molecular pharmacology 20060601 |
| Progesterone's effects to reduce anxiety behavior of aged mice do not require actions via intracellular progestin receptors. | Psychopharmacology 20060601 |
| Neonatal neurosteroid administration results in development-specific alterations in prepulse inhibition and locomotor activity: neurosteroids alter prepulse inhibition and locomotor activity. | Psychopharmacology 20060601 |
| Effects of some neurosteroids injected into some brain areas of WAG/Rij rats, an animal model of generalized absence epilepsy. | Neuropharmacology 20060601 |
| Activity of B-nor analogues of neurosteroids on the GABA(A) receptor in primary neuronal cultures. | Journal of medicinal chemistry 20060601 |
| Tolerance development to Morris water maze test impairments induced by acute allopregnanolone. | Neuroscience 20060512 |
| Impaired reduction of enhanced levels of dehydroepiandrosterone by oral dexamethasone in anorexia nervosa. | Psychoneuroendocrinology 20060501 |
| Allopregnanolone produces hyperphagia by reducing neophobia without altering food palatability. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060501 |
| Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity. | Psychoneuroendocrinology 20060501 |
| Gonadotropin stimulation of steroid synthesis and metabolism in the Rana pipiens ovarian follicle: sequential changes in endogenous steroids during ovulation, fertilization and cleavage stages. | The Journal of steroid biochemistry and molecular biology 20060501 |
| Allopregnanolone and ganaxolone increase the firing activity of dorsal raphe nucleus serotonergic neurons in female rats. | The international journal of neuropsychopharmacology 20060401 |
| Injury elicited increase in spinal cord neurosteroid content analyzed by gas chromatography mass spectrometry. | Endocrinology 20060401 |
| Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion. | Annals of emergency medicine 20060401 |
| Rats bred for high versus low anxiety responses neonatally demonstrate increases in lordosis, pacing behavior, and midbrain 3 alpha, 5 alpha-THP levels as adults. | Behavioral neuroscience 20060401 |
| GABA(A) receptor changes in acute allopregnanolone tolerance. | European journal of pharmacology 20060327 |
| Differential effect of kinase A and C blockers on lordosis facilitation by progesterone and its metabolites in ovariectomized estrogen-primed rats. | Hormones and behavior 20060301 |
| Effects of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one on ethanol-mediated paired-pulse depression of population spikes in the CA1 region of rat hippocampal slices. | Neuroscience letters 20060206 |
| Syntheses of 19-[O-(carboxymethyl)oxime] haptens of epipregnanolone and pregnanolone. | Steroids 20060201 |
| 3alpha-OL-5-beta-pregnan-20-one hemisuccinate, a steroidal low-affinity NMDA receptor antagonist improves clinical rating scores in a rabbit multiple infarct ischemia model: synergism with tissue plasminogen activator. | Experimental neurology 20060201 |
| Selected line difference in sensitivity to a GABAergic neurosteroid during ethanol withdrawal. | Genes, brain, and behavior 20060201 |
| Understanding how the brain perceives alcohol: neurobiological basis of ethanol discrimination. | Alcoholism, clinical and experimental research 20060201 |
| Preclinical analyses of the therapeutic potential of allopregnanolone to promote neurogenesis in vitro and in vivo in transgenic mouse model of Alzheimer's disease. | Current Alzheimer research 20060201 |
| Histories of depression, allopregnanolone responses to stress, and premenstrual symptoms in women. | Biological psychology 20060101 |
| Analysis of derivatised steroids by matrix-assisted laser desorption/ionisation and post-source decay mass spectrometry. | Steroids 20060101 |
| Circulating neuroactive C21- and C19-steroids in young men before and after ejaculation. | Physiological research 20060101 |
| Action of two neuroactive steroids against motor seizures induced by pentetrazol in rats during ontogeny. | Physiological research 20060101 |
| Synthesis of 3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxyl-methyl-5alpha-pregnan-20-one via lithium imidazole with 17alpha-acetylbromopregnanone. | Steroids 20060101 |
| 3alpha-hydroxy-5alpha-pregnan-20-one in the midbrain ventral tegmental area mediates social, sexual, and affective behaviors. | Neuroscience 20060101 |
| Peripheral-type benzodiazepine receptor in neurosteroid biosynthesis, neuropathology and neurological disorders. | Neuroscience 20060101 |
| Anti-apoptotic effects of allopregnanolone on P19 neurons. | The European journal of neuroscience 20060101 |
| Perinatal allopregnanolone influences prefrontal cortex structure, connectivity and behavior in adult rats. | Neuroscience 20060101 |
| Metformin administration modulates neurosteroids secretion in non-obese amenorrhoic patients with polycystic ovary syndrome. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060101 |
| Prediction models for insulin resistance in girls with premature adrenarche. The premature adrenarche insulin resistance score: PAIR score. | Hormone research 20060101 |
| Effect of tibolone administration on central and peripheral levels of allopregnanolone and beta-endorphin in female rats. | Menopause (New York, N.Y.) 20060101 |
| Hypoxia potentiates endotoxin-induced allopregnanolone concentrations in the newborn brain. | Biology of the neonate 20060101 |
| Biosynthesis and organizing action of neurosteroids in the developing Purkinje cell. | Cerebellum (London, England) 20060101 |
| Progesterone and medroxyprogesterone acetate effects on central and peripheral allopregnanolone and beta-endorphin levels. | Neuroendocrinology 20060101 |
| Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls. | Prostaglandins, leukotrienes, and essential fatty acids 20060101 |
| Progestin concentrations are increased following paced mating in midbrain, hippocampus, diencephalon, and cortex of rats in behavioral estrus, but only in midbrain of diestrous rats. | Neuroendocrinology 20060101 |
| Stress in pregnancy activates neurosteroid production in the fetal brain. | Neuroendocrinology 20060101 |
| Anticonvulsant action of three neurosteroids against cortical epileptic afterdischarges in immature rats. | Brain research bulletin 20051230 |
| Allopregnanolone treatment, both as a single injection or repetitively, delays demyelination and enhances survival of Niemann-Pick C mice. | Journal of neuroscience research 20051215 |
| The anxiolytic etifoxine activates the peripheral benzodiazepine receptor and increases the neurosteroid levels in rat brain. | Pharmacology, biochemistry, and behavior 20051201 |
| Social isolation-induced changes in the hypothalamic-pituitary-adrenal axis in the rat. | Stress (Amsterdam, Netherlands) 20051201 |
| The intrahippocampal administration of the neurosteroid allopregnanolone blocks the audiogenic seizures induced by nicotine. | Brain research 20051116 |
| Low concentrations of neuroactive steroids alter kinetics of [3H]ifenprodil binding to the NMDA receptor in rat frontal cortex. | British journal of pharmacology 20051101 |
| 3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20051101 |
| [Effects of morphine dependence on the levels of neurosteroids in rat brain]. | Yao xue xue bao = Acta pharmaceutica Sinica 20051101 |
| Intrahippocampal nicotine and neurosteroids effects on the anxiety-like behaviour in voluntary and chronic alcohol-drinking rats. | Behavioural brain research 20051014 |
| Short-term steroid treatment increases delta GABAA receptor subunit expression in rat CA1 hippocampus: pharmacological and behavioral effects. | Neuropharmacology 20051001 |
| The effect of a low dose of alcohol on allopregnanolone serum concentrations across the menstrual cycle in women with severe premenstrual syndrome and controls. | Psychoneuroendocrinology 20051001 |
| Negative GABA(A) modulators attenuate the discriminative stimulus effects of benzodiazepines and the neuroactive steroid pregnanolone in rhesus monkeys. | Psychopharmacology 20051001 |
| Evaluation of O(3alpha)-, O(21)-di-(N(1)-methyloxycarbonyl-2, 4-dioxo-5-fluoropyrimidinyl) 17alpha-hydroxy-5beta-pregnan-20-one as a novel potential antiangiogenic codrug. | Journal of enzyme inhibition and medicinal chemistry 20051001 |
| Interaction of cocaine with positive GABAA modulators on the repeated acquisition and performance of response sequences in rats. | Psychopharmacology 20050901 |
| Low serum allopregnanolone levels in girls with precocious pubarche. | Steroids 20050901 |
| High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABA A receptors by neurosteroids and GABA agonists. | Neuropharmacology 20050901 |
| Neurosteroids exhibit differential effects on mIPSCs recorded from normal and seizure prone rats. | Journal of neurophysiology 20050901 |
| Inhibiting biosynthesis and/or metabolism of progestins in the ventral tegmental area attenuates lordosis of rats in behavioural oestrus. | Journal of neuroendocrinology 20050901 |
| Alphaxalone and epiallopregnanolone in rats trained to discriminate ethanol. | Alcoholism, clinical and experimental research 20050901 |
| Neurosteroid modulators of GABA(A) receptors differentially modulate Ethanol intake patterns in male C57BL/6J mice. | Alcoholism, clinical and experimental research 20050901 |
| Effects of intrahippocampal nicotine and neurosteroid administration on withdrawal in voluntary and chronic alcohol-drinking rats. | Alcoholism, clinical and experimental research 20050901 |
| Novel 17beta-substituted conformationally constrained neurosteroids that modulate GABA A receptors. | Journal of medicinal chemistry 20050811 |
| Characterization of the discriminative stimulus effects of the neuroactive steroid pregnanolone in DBA/2J and C57BL/6J inbred mice. | The Journal of pharmacology and experimental therapeutics 20050801 |
| Dehydroepiandrosterone sulfate and allopregnanolone directly stimulate catecholamine production via induction of tyrosine hydroxylase and secretion by affecting actin polymerization. | Endocrinology 20050801 |
| Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons. | Journal of neurochemistry 20050801 |
| Estrogen-priming can enhance progesterone's anti-seizure effects in part by increasing hippocampal levels of allopregnanolone. | Pharmacology, biochemistry, and behavior 20050801 |
| [Stress and sleep/emotional disorder: possible involvement of neurosteroid allopregnanolone]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20050801 |
| Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: potential role of endogenous neurosteroids? | Alcohol (Fayetteville, N.Y.) 20050801 |
| Discriminative stimulus effects of 5.6 mg/kg pregnanolone in DBA/2J and C57BL/6J inbred mice. | Alcohol (Fayetteville, N.Y.) 20050801 |
| [Effects of pregnanolone on spontaneous firing of pain nucleus of habenula in rats]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050801 |
| Allopregnanolone and pregnanolone are produced by the human corpus luteum. | Molecular and cellular endocrinology 20050715 |
| Termination of pseudopregnancy in the rat alters the response to progesterone, chlordiazepoxide, and MK-801 in the elevated plus-maze. | Psychopharmacology 20050701 |
| Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats. | Psychopharmacology 20050701 |
| Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction. | Steroids 20050701 |
| Nanomolar allopregnanolone potentiates rat cerebellar GABAA receptors. | Neuroscience letters 20050701 |
| Epipregnanolone and a novel synthetic neuroactive steroid reduce alcohol self-administration in rats. | Pharmacology, biochemistry, and behavior 20050701 |
| Increased brain concentrations of a neuroinhibitory steroid in human hepatic encephalopathy. | Annals of neurology 20050701 |
| Neuroactive steroids and ethanol. | Alcoholism, clinical and experimental research 20050701 |
| Two new pregnanone derivatives with strong cytotoxic activity from Pachysandra axillaris. | Chemistry & biodiversity 20050701 |
| Plasma concentrations of anxiolytic neuroactive steroids in men with panic disorder. | Psychiatry research 20050630 |
| Reinstatement of serum pregnanolone isomers and progesterone during alcohol detoxification therapy in premenopausal women. | Alcoholism, clinical and experimental research 20050601 |
| The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050511 |
| Cortical 3 alpha-hydroxy-5 alpha-pregnan-20-one levels after acute administration of Delta 9-tetrahydrocannabinol, cocaine and morphine. | Psychopharmacology 20050501 |
| Differences in affective behaviors and hippocampal allopregnanolone levels in adult rats of lines selectively bred for infantile vocalizations. | Behavioural brain research 20050430 |
| Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. | Journal of medicinal chemistry 20050421 |
| Intracellular oxidation of allopregnanolone by human brain type 10 17beta-hydroxysteroid dehydrogenase. | Brain research 20050408 |
| Isoallopregnanolone; an antagonist to the anaesthetic effect of allopregnanolone in male rats. | European journal of pharmacology 20050404 |
| Combined discriminative stimulus effects of midazolam with other positive GABAA modulators and GABAA receptor agonists in rhesus monkeys. | Psychopharmacology 20050401 |
| New evidence that both T-type calcium channels and GABAA channels are responsible for the potent peripheral analgesic effects of 5alpha-reduced neuroactive steroids. | Pain 20050401 |
| Reversal of caffeine-induced anxiety by neurosteroid 3-alpha-hydroxy-5-alpha-pregnane-20-one in rats. | Neuropharmacology 20050401 |
| Effect of dehydroepiandrosterone on central and peripheral levels of allopregnanolone and beta-endorphin. | Fertility and sterility 20050401 |
| Rapid non-genomic effect of glucocorticoid metabolites and neurosteroids on the gamma-aminobutyric acid-A receptor. | The European journal of neuroscience 20050401 |
| Progesterone's 5 alpha-reduced metabolite, 3 alpha,5 alpha-THP, mediates lateral displacement of hamsters. | Brain research 20050315 |
| In the ventral tegmental area picrotoxin blocks FGIN 1-27-induced increases in sexual behavior of rats and hamsters. | Psychopharmacology 20050301 |
| Antidepressant-like actions of intra-accumbens infusions of allopregnanolone in ovariectomized Wistar rats. | Pharmacology, biochemistry, and behavior 20050301 |
| Tibolone, transdermal estradiol or oral estrogen-progestin therapies: effects on circulating allopregnanolone, cortisol and dehydroepiandrosterone levels. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050301 |
| Relationship between allopregnanolone and negative mood in postmenopausal women taking sequential hormone replacement therapy with vaginal progesterone. | Psychoneuroendocrinology 20050201 |
| Interaction between allopregnanolone and pregnenolone sulfate in modulating GABA-mediated synaptic currents in neurons from the rat medial preoptic nucleus. | Brain research 20050201 |
| Anesthetic effects of progesterone are undiminished in progesterone receptor knockout mice. | Brain research 20050201 |
| Changes in bovine luteal progesterone metabolism in response to exogenous prostaglandin F(2alpha). | Domestic animal endocrinology 20050201 |
| Post-ictal circulating levels of allopregnanolone in children with partial or generalized seizures. | Epilepsy research 20050201 |
| New colchicinoids from a native Jordanian meadow saffron, colchicum brachyphyllum: isolation of the first naturally occurring dextrorotatory colchicinoid. | Journal of natural products 20050201 |
| The effect of dehydroepiandrosterone sulfate and allopregnanolone sulfate on the binding of [(3)H]ifenprodil to the N-methyl-d-aspartate receptor in rat frontal cortex membrane. | The Journal of steroid biochemistry and molecular biology 20050201 |
| Termination of pseudopregnancy in the rat produces an anxiogenic-like response that is associated with an increase in benzodiazepine receptor binding density and a decrease in GABA-stimulated chloride influx in the hippocampus. | Brain research bulletin 20050130 |
| Estradiol and the addition of progesterone increase the sensitivity to a neurosteroid in postmenopausal women. | Psychoneuroendocrinology 20050101 |
| Neuroactive pregnanolone isomers during pregnancy. | The Journal of clinical endocrinology and metabolism 20050101 |
| Anxiolytic activity of progesterone in progesterone receptor knockout mice. | Neuropharmacology 20050101 |
| Electrophysiological effects of allopregnanolone in rats with a history of ethanol exposure. | Alcoholism, clinical and experimental research 20050101 |
| The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats. | Journal of neurotrauma 20050101 |
| Behavioral sensitization to ethanol is modulated by environmental conditions, but is not associated with cross-sensitization to allopregnanolone or pentobarbital in DBA/2J mice. | Neuroscience 20050101 |
| [The role of neurosteroids in the central nervous system function]. | Przeglad lekarski 20050101 |
| 3alpha,5alpha-Tetrahydroprogesterone (allopregnanolone) and gamma-aminobutyric acid: autocrine/paracrine interactions in the control of neonatal PSA-NCAM+ progenitor proliferation. | Journal of neuroscience research 20041215 |
| Discriminative stimulus effects of ethanol in rats using a three-choice ethanol-midazolam-water discrimination. | Behavioural pharmacology 20041201 |
| Role of neurosteroids in catamenial epilepsy. | Epilepsy research 20041201 |
| Synergistic interaction between ketoconazole and several antidepressant drugs with allopregnanolone treatments in ovariectomized Wistar rats forced to swim. | Progress in neuro-psychopharmacology & biological psychiatry 20041201 |
| Disadaptive disorders in women: allopregnanolone, a sensitive steroid. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20041201 |
| Role of alcohol consumption in escalation to violence. | Annals of the New York Academy of Sciences 20041201 |
| Progesterone attenuates corticotropin-releasing factor-enhanced but not fear-potentiated startle via the activity of its neuroactive metabolite, allopregnanolone. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110 |
| Effects of PhD examination stress on allopregnanolone and cortisol plasma levels and peripheral benzodiazepine receptor density. | Psychoneuroendocrinology 20041101 |
| Niemann pick type C disease as a model for defects in neurosteroidogenesis. | Endocrine research 20041101 |
| Increased allopregnanolone levels in the fetal sheep brain following umbilical cord occlusion. | The Journal of physiology 20041015 |
| Role of allopregnanolone on cerebellar granule cells neurogenesis. | Brain research. Developmental brain research 20041015 |
| Essentiality of central GABAergic neuroactive steroid allopregnanolone for anticonvulsant action of fluoxetine against pentylenetetrazole-induced seizures in mice. | Brain research 20041008 |
| Allopregnanolone does not influence ethanol-induced conditioned place preference in DBA/2J mice. | Psychopharmacology 20041001 |
| Dynamic aspects of acute tolerance to allopregnanolone evaluated using anaesthesia threshold in male rats. | British journal of anaesthesia 20041001 |
| Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury. | Experimental neurology 20041001 |
| Modulation of GABA(A) receptor gene expression by allopregnanolone and ethanol. | European journal of pharmacology 20041001 |
| Influence of 17beta-estradiol on the synthesis of reduced neurosteroids in the brain (in vivo) and in glioma cells (in vitro): possible relevance to mental disorders in women. | Brain research 20040910 |
| Role of neuroactive steroid allopregnanolone in antipsychotic-like action of olanzapine in rodents. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040901 |
| Impact of neuropathic pain on the gene expression and activity of cytochrome P450side-chain-cleavage in sensory neural networks. | Cellular and molecular life sciences : CMLS 20040901 |
| Fetal alcohol exposure alters neurosteroid levels in the developing rat brain. | Journal of neurochemistry 20040901 |
| 3beta-20beta-dihydroxy-5alpha-pregnane (UC1011) antagonism of the GABA potentiation and the learning impairment induced in rats by allopregnanolone. | The European journal of neuroscience 20040901 |
| Pharmacology of catamenial epilepsy. | Methods and findings in experimental and clinical pharmacology 20040901 |
| [Pregnanolone effects on the blood pressure of stress-induced hypertension in rats]. | Sheng li xue bao : [Acta physiologica Sinica] 20040825 |
| Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study. | Journal of clinical psychopharmacology 20040801 |
| Ethanol-induced elevation of 3 alpha-hydroxy-5 alpha-pregnan-20-one does not modulate motor incoordination in rats. | Alcoholism, clinical and experimental research 20040801 |
| Slow actions of neuroactive steroids at GABAA receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040728 |
| Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040721 |
| Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice. | The Journal of pharmacology and experimental therapeutics 20040701 |
| Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone. | Nature medicine 20040701 |
| Insight into the mechanism of action of neuroactive steroids. | Molecular pharmacology 20040701 |
| Dipole potential and head-group spacing are determinants for the membrane partitioning of pregnanolone. | Molecular pharmacology 20040701 |
| Allopregnanolone in the brain and blood after disruption of the hypothalamic-pituitary-adrenal axis in fetal sheep. | The Journal of endocrinology 20040701 |
| Brain on steroids resists neurodegeneration. | Nature medicine 20040701 |
| Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice. | Epilepsia 20040701 |
| Progestins' actions in the VTA to facilitate lordosis involve dopamine-like type 1 and 2 receptors. | Pharmacology, biochemistry, and behavior 20040701 |
| Interaction of chronic ethanol exposure and finasteride: sex and strain differences. | Pharmacology, biochemistry, and behavior 20040701 |
| Sexually dimorphic effects of postnatal allopregnanolone on the development of anxiety behavior after early deprivation. | Pharmacology, biochemistry, and behavior 20040701 |
| 3alpha,5alpha-THP mediates progestins' effects to protect against adrenalectomy-induced cell death in the dentate gyrus of female and male rats. | Pharmacology, biochemistry, and behavior 20040701 |
| Hippocampal 3alpha,5alpha-THP may alter depressive behavior of pregnant and lactating rats. | Pharmacology, biochemistry, and behavior 20040701 |
| Neonatal neurosteroid administration alters parvalbumin expression and neuron number in medial dorsal thalamus of adult rats. | Brain research 20040625 |
| Panic disorder in menopause: a case control study. | Maturitas 20040615 |
| Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy. | The Journal of physiology 20040601 |
| Acute neurosteroid modulation and subunit isolation of the gamma-aminobutyric acidA receptor in the bullfrog, Rana catesbeiana. | Journal of molecular endocrinology 20040601 |
| Protective effect of pregnanolone against lipoperoxidation and free radicals generation induced in hypothalamus of ovariectomized rats submitted to CO2 exposure. | Pharmacology, biochemistry, and behavior 20040601 |
| Sites of positive allosteric modulation by neurosteroids on ionotropic gamma-aminobutyric acid receptor subunits. | FEBS letters 20040521 |
| Teaching resources. Regulation of GABA receptor activity by neurosteroids and phosphorylation. | Science's STKE : signal transduction knowledge environment 20040518 |
| Identification of 3beta,5beta-tetrahydroprogesterone, a progesterone metabolite, and its stimulatory action on preoptic neurons in the avian brain. | Brain research 20040508 |
| The interaction of anaesthetic steroids with recombinant glycine and GABAA receptors. | British journal of anaesthesia 20040501 |
| Chronic prenatal ethanol exposure alters hippocampal GABA(A) receptors and impairs spatial learning in the guinea pig. | Behavioural brain research 20040402 |
| Administration of progesterone produces mild sedative-like effects in men and women. | Psychoneuroendocrinology 20040401 |
| Effects of pregnanolone alone and in combination with other positive GABAA modulators on complex behavior in rats. | Psychopharmacology 20040401 |
| Alcohol intoxication increases allopregnanolone levels in male adolescent humans. | Psychopharmacology 20040301 |
| Estradiol and testosterone modulate the anesthetic action of the GABA-A agonist THIP, but not of the neurosteroid 3alpha,5beta-pregnanolone in the rat. | Psychopharmacology 20040301 |
| Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function. | Neuropharmacology 20040301 |
| Conjugated equine estrogens reverse the effects of aging on central and peripheral allopregnanolone and beta-endorphin levels in female rats. | Fertility and sterility 20040301 |
| Psychological effect of the oral contraceptive formulation containing 3 mg of drospirenone plus 30 microg of ethinyl estradiol. | Fertility and sterility 20040301 |
| Synthesis of [19- 2H3]-analogs of dehydroepiandrosterone and pregnenolone and their sulfates. | Steroids 20040301 |
| Chronic antidepressants reverse cerebrocortical allopregnanolone decline in the olfactory-bulbectomized rat. | European journal of pharmacology 20040213 |
| The neuroactive steroid 3-alpha-ol-5-beta-pregnan-20-one hemisuccinate, a selective NMDA receptor antagonist improves behavioral performance following spinal cord ischemia. | Brain research 20040206 |
| Cytochrome P450 2D catalyze steroid 21-hydroxylation in the brain. | Endocrinology 20040201 |
| Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia. | The Journal of pharmacology and experimental therapeutics 20040201 |
| Elevated levels of some neuroactive progesterone metabolites, particularly isopregnanolone, in women with chronic fatigue syndrome. | Psychoneuroendocrinology 20040201 |
| Studies on the mechanisms of action of picrotoxin, quercetin and pregnanolone at the GABA rho 1 receptor. | British journal of pharmacology 20040201 |
| The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches. | Pharmacology & therapeutics 20040201 |
| Adrenal response to adrenocorticotropic hormone stimulation in patients with premenstrual syndrome. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040201 |
| Production of 5alpha-reduced neurosteroids is developmentally regulated and shapes GABA(A) miniature IPSCs in lamina II of the spinal cord. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040128 |
| Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats. | European journal of pharmacology 20040126 |
| Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex. | Neuroscience 20040101 |
| Potentiated modulation of pregnolone on GABAA receptors in behaviorally stressed borderline-hypertensive rats. | Biological & pharmaceutical bulletin 20040101 |
| The implications of 7-dehydrosterol-7-reductase deficiency (Smith-Lemli-Opitz syndrome) to neurosteroid production. | Steroids 20040101 |
| The nitric oxide pathway participates in estrous behavior induced by progesterone and some of its ring A-reduced metabolites. | Hormones and behavior 20040101 |
| Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice. | Neuroscience 20040101 |
| Neuroactive steroids are not affected by panic induction with 50 microg cholecystokinin-tetrapeptide (CCK-4) in healthy volunteers. | Journal of psychiatric research 20040101 |
| Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo. | Journal of neuroendocrinology 20040101 |
| Allopregnanolone, a progesterone metabolite, enhances behavioral recovery and decreases neuronal loss after traumatic brain injury. | Restorative neurology and neuroscience 20040101 |
| Plasma concentrations of anxiolytic neurosteroids in men with normal anxiety scores: a correlation analysis. | Neuropsychobiology 20040101 |
| Ovariectomy and estradiol replacement therapy alters the adenine nucleotide hydrolysis in rat blood serum. | Thrombosis research 20040101 |
| Brain neurosteroids in gender-related aggression induced by social isolation. | Critical reviews in neurobiology 20040101 |
| [Determination of neurosteroids in rat brain by gas chromatography/mass spectrometry]. | Se pu = Chinese journal of chromatography 20040101 |
| Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one. | Journal of medicinal chemistry 20031204 |
| Circulating levels of neuroactive steroids in patients with binge eating disorder: a comparison with nonobese healthy controls and non-binge eating obese subjects. | The International journal of eating disorders 20031201 |
| Impairments in spatial learning and memory: ethanol, allopregnanolone, and the hippocampus. | Brain research. Brain research reviews 20031201 |
| Neurosteroid consumption has anxiolytic effects in mice. | Pharmacology, biochemistry, and behavior 20031201 |
| Conditional regulation of neurosteroid sensitivity of GABAA receptors. | Annals of the New York Academy of Sciences 20031201 |
| Pathogenesis in menstrual cycle-linked CNS disorders. | Annals of the New York Academy of Sciences 20031201 |
| The contraceptive agent Provera enhances GABA(A) receptor-mediated inhibitory neurotransmission in the rat hippocampus: evidence for endogenous neurosteroids? | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031105 |
| Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor. | Journal of medicinal chemistry 20031023 |
| Vaginal administration of allopregnanolone to postmenopausal women undergoing estrogen replacement therapy: preliminary results. | Maturitas 20031020 |
| 5alpha-reduced C21 steroids are substrates for human cytochrome P450c17. | Archives of biochemistry and biophysics 20031015 |
| Brain neurosteroid changes after paroxetine administration in mice. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20031001 |
| Neurosteroids alter gamma-aminobutyric acid postsynaptic currents in gonadotropin-releasing hormone neurons: a possible mechanism for direct steroidal control. | Endocrinology 20031001 |
| Steroid-sensitive GABAA receptors in the fetal sheep brain. | Neuropharmacology 20030901 |
| Acylated-oxypregnane glycosides from the roots of Araujia sericifera. | Chemical & pharmaceutical bulletin 20030901 |
| Catamenial epilepsy: pathophysiology, diagnosis, and management. | Neurology 20030901 |
| Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnan-20-one (isoallopregnanolone). | Brain research 20030822 |
| Structure-activity relationships in carboxamide derivatives based on the targeted delivery of radionuclides and boron atoms by means of peripheral benzodiazepine receptor ligands. | Journal of medicinal chemistry 20030814 |
| Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats. | Brain research 20030808 |
| Protective efficacy of neuroactive steroids against cocaine kindled-seizures in mice. | European journal of pharmacology 20030808 |
| Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum. | Journal of neurochemistry 20030801 |
| Modulation of GABAA receptors and neuropeptide secretion by the neurosteroid allopregnanolone in posterior and intermediate pituitary. | Pharmacology & toxicology 20030801 |
| The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway. | The Journal of clinical endocrinology and metabolism 20030801 |
| Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats. | Psychopharmacology 20030701 |
| Inhibition of NMDA-induced striatal dopamine release and behavioral activation by the neuroactive steroid 3alpha-hydroxy-5beta-pregnan-20-one hemisuccinate. | Journal of neurochemistry 20030701 |
| Long-term social isolation enhances picrotoxin seizure susceptibility in mice: up-regulatory role of endogenous brain allopregnanolone in GABAergic systems. | Pharmacology, biochemistry, and behavior 20030701 |
| Region-specific dysregulation of allopregnanolone brain content in the olfactory bulbectomized rat model of depression. | Brain research 20030620 |
| Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in the perinatal sheep. | Pediatric research 20030601 |
| Alcohol intoxication increases allopregnanolone levels in female adolescent humans. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030601 |
| Neurocognitive functioning in subjects with eating disorders: the influence of neuroactive steroids. | Biological psychiatry 20030515 |
| Deletion of GABAA receptor alpha 1 subunit-containing receptors alters responses to ethanol and other anesthetics. | The Journal of pharmacology and experimental therapeutics 20030501 |
| Anxiogenic effects of neurosteroid exposure: sex differences and altered GABAA receptor pharmacology in adult rats. | The Journal of pharmacology and experimental therapeutics 20030501 |
| GABA(A) receptor active steroids are altered in epilepsy patients with tuberous sclerosis. | Journal of neurology, neurosurgery, and psychiatry 20030501 |
| Anti-conflict-like actions of intralateral septal infusions of allopregnanolone in Wistar rats. | Pharmacology, biochemistry, and behavior 20030501 |
| Comparison of the effects of allopregnanolone with direct GABAergic agonists on ethanol self-administration with and without concurrently available sucrose. | Alcohol (Fayetteville, N.Y.) 20030501 |
| Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain. | The Journal of biological chemistry 20030411 |
| Neurosteroid regulation of oxytocin and vasopressin release from the rat supraoptic nucleus. | The Journal of physiology 20030401 |
| Neurosteroid effects on GABAergic synaptic plasticity in hippocampus. | Journal of neurophysiology 20030401 |
| Adrenal function under long-term raloxifene administration. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030401 |
| Allopregnanolone serum levels and expression of 5 alpha-reductase and 3 alpha-hydroxysteroid dehydrogenase isoforms in hippocampal and temporal cortex of patients with epilepsy. | Epilepsy research 20030401 |
| Inter-ictal and post-ictal circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in epileptic children. | Epilepsy research 20030401 |
| Effect of acute ethanol administration and acute allopregnanolone administration on spontaneous hippocampal pyramidal cell neural activity. | Brain research 20030328 |
| Seizure exacerbation associated with inhibition of progesterone metabolism. | Annals of neurology 20030301 |
| Neuroactive steroid levels in patients with panic disorder. | The American journal of psychiatry 20030301 |
| Perinatal neurosteroid levels influence GABAergic interneuron localization in adult rat prefrontal cortex. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301 |
| Synthesis and GABA(A) receptor activity of a 6,19-oxido analogue of pregnanolone. | Bioorganic & medicinal chemistry letters 20030210 |
| Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201 |
| Induced panic attacks shift gamma-aminobutyric acid type A receptor modulatory neuroactive steroid composition in patients with panic disorder: preliminary results. | Archives of general psychiatry 20030201 |
| GABA receptors, progesterone and premenstrual dysphoric disorder. | Archives of women's mental health 20030201 |
| Effect of different hormonal replacement therapies on circulating allopregnanolone and dehydroepiandrosterone levels in postmenopausal women. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030201 |
| Neurosteroids in depression: a review. | Psychopharmacology 20030101 |
| Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101 |
| On the putative physiological role of allopregnanolone on GABA(A) receptor function. | Neuropharmacology 20030101 |
| Pregnanolone isomers, pregnenolone and their polar conjugates around parturition. | Physiological research 20030101 |
| Increased neurosteroid sensitivity of hippocampal GABAA receptors during postnatal development. | Neuroscience 20030101 |
| Serum allopregnanolone levels relate to FSFI score during the menstrual cycle. | Journal of sex & marital therapy 20030101 |
| Effects of neurosteroids on epileptiform activity induced by picrotoxin and 4-aminopyridine in the rat hippocampal slice. | Epilepsy research 20030101 |
| A synthesis of 3alpha,6alpha,17alpha-trihydroxy-5beta-pregnan-20-one (triolone) from 3alpha,6alpha-dihydroxy-5beta-pregnan-20-one (diolone). | Acta poloniae pharmaceutica 20030101 |
| Inhibitory effect of some neuroactive steroids on cocaine-induced kindling in mice. | Polish journal of pharmacology 20030101 |
| The third multidisciplinary conference on drug research, Piła 2002. Effects of 1alpha,25-dihydroxyvitamin D3 and some putative steroid neuroprotective agents on the hydrogen peroxide-induced damage in neuroblastoma-glioma hybrid NG108-15 cells. | Acta poloniae pharmaceutica 20030101 |
| Allopregnanolone modulates spontaneous GABA release via presynaptic Cl- permeability in rat preoptic nerve terminals. | Brain research 20021227 |
| Allopregnanolone enhancement of GABAergic transmission in rat medial preoptic area neurons. | American journal of physiology. Endocrinology and metabolism 20021201 |
| Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride. | Journal of neurochemistry 20021201 |
| Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, ganaxolone in cultured rat cerebellar granule cells. | The Journal of pharmacology and experimental therapeutics 20021201 |
| Endotoxin increases sleep and brain allopregnanolone concentrations in newborn lambs. | Pediatric research 20021201 |
| A caspase-3-dependent pathway is predominantly activated by the excitotoxin pregnenolone sulfate and requires early and late cytochrome c release and cell-specific caspase-2 activation in the retinal cell death. | Journal of neurochemistry 20021201 |
| Behavioral action of ethanol in Porsolt's forced swim test: modulation by 3 alpha-hydroxy-5 alpha-pregnan-20-one. | Neuropharmacology 20021201 |
| Conjugated equine estrogens, estrone sulphate and estradiol valerate oral administration in ovariectomized rats: effects on central and peripheral allopregnanolone and beta-endorphin. | Maturitas 20021120 |
| Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2). | Biochemistry 20021112 |
| Acute hypoxic hypoxia alters GABA(A) receptor modulation by allopregnanolone and pentobarbital in embryonic chick optic lobe. | Brain research 20021108 |
| Neuroactive steroids differ in potency but not in intrinsic efficacy at the GABA(A) receptor in vivo. | The Journal of pharmacology and experimental therapeutics 20021101 |
| Acute and chronic effects of the neuroactive steroid pregnanolone on schedule-controlled responding in rhesus monkeys. | Behavioural pharmacology 20021101 |
| Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients. | The Journal of clinical endocrinology and metabolism 20021101 |
| Acute ethanol administration and acute allopregnanolone administration impair spatial memory in the Morris water task. | Alcoholism, clinical and experimental research 20021101 |
| Allopregnanolone levels and symptom improvement in severe premenstrual syndrome. | Journal of clinical psychopharmacology 20021001 |
| Functional characterization of GABA(A) receptors in neonatal hypothalamic brain slice. | Journal of neurophysiology 20021001 |
| Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon. | The Journal of clinical investigation 20021001 |
| Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems. | Psychopharmacology 20021001 |
| Aggressive behavior as a reinforcer in mice: activation by allopregnanolone. | Psychopharmacology 20021001 |
| Levels of testosterone, allopregnanolone and homocysteine in severe hypothyroidism. | Clinical chemistry and laboratory medicine 20021001 |
| Allopregnanolone activates GABA(A) receptor/Cl(-) channels in a multiphasic manner in embryonic rat hippocampal neurons. | Journal of neurophysiology 20020901 |
| Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study. | Archives of general psychiatry 20020901 |
| Biosynthesis of steroids in ovarian follicles of red seabream, Pagrus major (Sparidae, Teleostei) during final oocyte maturation and the relative effectiveness of steroid metabolites for germinal vesicle breakdown in vitro. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020901 |
| Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery. | Journal of neurochemistry 20020901 |
| The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors. | Neuropharmacology 20020901 |
| Progesterone withdrawal increases the alpha4 subunit of the GABA(A) receptor in male rats in association with anxiety and altered pharmacology - a comparison with female rats. | Neuropharmacology 20020901 |
| Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture. | Neuroscience letters 20020802 |
| Neonatal isolation alters stress hormone and mesolimbic dopamine release in juvenile rats. | Pharmacology, biochemistry, and behavior 20020801 |
| Alcohol-induced c-Fos expression in the Edinger-Westphal nucleus: pharmacological and signal transduction mechanisms. | The Journal of pharmacology and experimental therapeutics 20020801 |
| Differential effects of allopregnanolone and GABA on kainate-induced lactate dehydrogenase release in cultured rat cerebral cortical cells. | Acta pharmacologica Sinica 20020801 |
| Alteration of voluntary ethanol and saccharin consumption by the neurosteroid allopregnanolone in mice. | Psychopharmacology 20020801 |
| Allopregnanolone increase in striatal N-methyl-D-aspartic acid evoked [3H]dopamine release is estrogen and progesterone dependent. | Cellular and molecular neurobiology 20020801 |
| Reinforcing effects of the neurosteroid allopregnanolone in rats. | Pharmacology, biochemistry, and behavior 20020701 |
| Antagonism of picrotoxin-induced changes in dopamine and serotonin metabolism by allopregnanolone and midazolam. | Pharmacology, biochemistry, and behavior 20020701 |
| Initial sensitivity, tolerance and cross-tolerance to allopregnanolone- and ethanol-induced hypothermia in selected mouse lines. | Psychopharmacology 20020701 |
| The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens. | The European journal of neuroscience 20020701 |
| Low pregnenolone sulphate plasma concentrations in patients with generalized social phobia. | Psychological medicine 20020701 |
| The clinical potentials of endogenous neurosteroids. | Drugs of today (Barcelona, Spain : 1998) 20020701 |
| Prevention of the stress-induced increase in the concentration of neuroactive steroids in rat brain by long-term administration of mirtazapine but not of fluoxetine. | Journal of psychopharmacology (Oxford, England) 20020601 |
| Effect of allopregnanolone on d-[3H]-aspartate release and [3H]-glutamate uptake in the hippocampus of kainate-treated mice. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020601 |
| Rapid anxiolytic activity of progesterone and pregnanolone in male rats. | Pharmacology, biochemistry, and behavior 20020601 |
| Female Wistar rats tested during late proestrus or during pregnancy and ovariectomized rats tested after receiving progesterone or allopregnanolone displayed reduced conflict behavior. | Progress in neuro-psychopharmacology & biological psychiatry 20020601 |
| Allopregnanolone inhibits learning in the Morris water maze. | Brain research 20020503 |
| Neuroactive steroid changes in response to challenge with the panicogenic agent pentagastrin. | Psychoneuroendocrinology 20020501 |
| Withdrawal properties of a neuroactive steroid: implications for GABA(A) receptor gene regulation in the brain and anxiety behavior. | Steroids 20020501 |
| Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats. | Hormones and behavior 20020501 |
| The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one affects dopamine-mediated behavior in rodents. | Psychopharmacology 20020501 |
| High serum allopregnanolone levels in girls with precocious puberty. | The Journal of clinical endocrinology and metabolism 20020501 |
| Effects of the new generation selective estrogen receptor modulator EM-652 and oral administration of estradiol valerate on circulating, brain, and adrenal beta-endorphin and allopregnanolone levels in intact fertile and ovariectomized rats. | Fertility and sterility 20020501 |
| GABA(B) receptor-mediated increase of neurosteroids by gamma-hydroxybutyric acid. | Neuropharmacology 20020501 |
| Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output. | Brain research 20020405 |
| Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20020401 |
| Two neuroactive steroids in midpregnancy as measured in maternal and fetal sera and in amniotic fluid. | Steroids 20020401 |
| Modulation Of [35S]-tert-butylbicyclophosphorothionate binding by somatostatin in rat hypothalamus. | Clinical and experimental pharmacology & physiology 20020401 |
| Substrate specificity of human 3(20)alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines. | Biological & pharmaceutical bulletin 20020401 |
| A rapid method for obtaining finasteride, a 5alpha-reductase inhibitor, from commercial tablets. | Brain research. Brain research protocols 20020401 |
| GABAergic neurosteroid modulation of ethanol actions. | The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20020401 |
| The effects of the neuroactive steroid 3 alpha,5 alpha-THDOC on sleep in the rat. | Neuroreport 20020325 |
| Daily treatment with diazepam differentially modifies sensitivity to the effects of gamma-aminobutyric acid(A) modulators on schedule-controlled responding in rhesus monkeys. | The Journal of pharmacology and experimental therapeutics 20020301 |
| Pulsatile secretory characteristics of allopregnanolone, a neuroactive steroid, during the menstrual cycle and in amenorrheic subjects. | European journal of endocrinology 20020301 |
| Changes in GABAA receptor gamma 2 subunit gene expression induced by long-term administration of oral contraceptives in rats. | Neuropharmacology 20020301 |
| Effect of centrally injected allopregnanolone on sexual receptivity, luteinizing hormone release, hypothalamic dopamine turnover, and release in female rats. | Endocrine 20020301 |
| Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids. | British journal of pharmacology 20020201 |
| Increased response of plasma allopregnanolone to corticotropin-releasing hormone in obese patients. | Neuroendocrinology 20020201 |
| Sensitivity to the locomotor stimulant effects of ethanol and allopregnanolone is influenced by common genes. | Behavioral neuroscience 20020201 |
| Social isolation stress during the third week of life has age-dependent effects on spatial learning in rats. | Behavioural brain research 20020122 |
| GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment. | The American journal of psychiatry 20020101 |
| Prenatal diazepam exposure functionally alters the GABA(A) receptor that modulates [3H]noradrenaline release from rat hippocampal synaptosomes. | Developmental neuroscience 20020101 |
| Ventral tegmental area infusions of inhibitors of the biosynthesis and metabolism of 3alpha,5alpha-THP attenuate lordosis of hormone-primed and behavioural oestrous rats and hamsters. | Journal of neuroendocrinology 20011201 |
| The interaction between ethanol and pregnanolone at induction of anaesthesia investigated with a threshold method in male rats. | British journal of pharmacology 20011201 |
| Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy. | The Journal of physiology 20011201 |
| Steroid structure and pharmacological properties determine the anti-amnesic effects of pregnenolone sulphate in the passive avoidance task in rats. | The European journal of neuroscience 20011201 |
| 3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex. | Brain research. Developmental brain research 20011126 |
| Neuroactive steroids modulate crustacean locomotor activity. | Neuroscience letters 20011102 |
| Influence of membrane cholesterol on modulation of the GABA(A) receptor by neuroactive steroids and other potentiators. | British journal of pharmacology 20011101 |
| The negative GABA(A) modulator methyl beta-carboline-3-carboxylate attenuates the behavioral effects of the positive GABA(A) modulators triazolam and pregnanolone in rhesus monkeys. | Psychopharmacology 20011101 |
| Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone. | Brain research. Brain research reviews 20011101 |
| The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5alpha-dihydroprogesterone in psychiatric disorders. | Brain research. Brain research reviews 20011101 |
| alpha4beta3delta GABA(A) receptors characterized by fluorescence resonance energy transfer-derived measurements of membrane potential. | The Journal of biological chemistry 20011019 |
| The influence of subchronic administration of the neurosteroid allopregnanolone on sleep in the rat. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20011001 |
| Pressure-sensitive and -insensitive coupling in gamma-aminobutyric acid(A) receptors. | Psychopharmacology 20011001 |
| Increased expression of the neuropeptide Y receptor Y(1) gene in the medial amygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone. | Journal of neurochemistry 20011001 |
| Allopregnanolone and pentobarbital infused into the nucleus accumbens substitute for the discriminative stimulus effects of ethanol. | Alcoholism, clinical and experimental research 20011001 |
| Neuroendocrine effects of raloxifene hydrochloride in postmenopausal women. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20011001 |
| Early postnatal ethanol intubation blunts GABA(A) receptor up-regulation and modifies 3alpha-hydroxy-5alpha-pregnan-20-one sensitivity in rat MS/DB neurons. | Brain research. Developmental brain research 20010923 |
| Immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase and 5 alpha-reductase in the brain of the African lungfish Protopterus annectens. | The Journal of comparative neurology 20010917 |
| Inhibiting progesterone metabolism in the hippocampus of rats in behavioral estrus decreases anxiolytic behaviors and enhances exploratory and antinociceptive behaviors. | Cognitive, affective & behavioral neuroscience 20010901 |
| 3alpha,5alpha-THP in the raphe magnus attenuates PTZ-induced myoclonic seizures. | Brain research 20010824 |
| Effects of progesterone synthesized de novo in the developing Purkinje cell on its dendritic growth and synaptogenesis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815 |
| Tolerance to the anticonvulsant activity of midazolam and allopregnanolone in a model of picrotoxin seizures. | European journal of pharmacology 20010810 |
| Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine. | Clinical chemistry and laboratory medicine 20010801 |
| Sensitivity of synaptic GABA(A) receptors to allosteric modulators in hippocampal oriens-alveus interneurons. | Synapse (New York, N.Y.) 20010701 |
| Neuroactive steroids, their precursors and polar conjugates during parturition and postpartum in maternal blood: 2. Time profiles of pregnanolone isomers. | The Journal of steroid biochemistry and molecular biology 20010701 |
| Effect of 5 alpha-pregnan-3 alpha-ol-20-one on nitric oxide biosynthesis and plasma volume in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20010601 |
| Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors. | Neuroscience letters 20010601 |
| Increased behavioral neurosteroid sensitivity in a rat line selectively bred for high alcohol sensitivity. | European journal of pharmacology 20010601 |
| Sensitivity to a neurosteroid is increased during addition of progestagen to postmenopausal hormone replacement therapy. | Neuroendocrinology 20010601 |
| In ovo chronic neurosteroid treatment affects the function and allosteric interactions of GABA(A) receptor modulatory sites. | Brain research 20010525 |
| Characterization of discriminative stimulus effects of the neuroactive steroid pregnanolone. | The Journal of pharmacology and experimental therapeutics 20010501 |
| Regulation of uterine gamma-aminobutyric acid(A) receptor subunit expression throughout pregnancy. | Endocrinology 20010501 |
| Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder. | Biological psychiatry 20010501 |
| Behavioral characterization of Co 134444 (3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid. | Psychopharmacology 20010501 |
| Effects of CRH and ACTH administration on plasma and brain neurosteroid levels. | Neurochemical research 20010501 |
| Cataleptic effect of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice: modulation by serotonergic agents. | Brain research 20010413 |
| Functional modulation of gamma-aminobutyric acid(A) receptors by etifoxine and allopregnanolone in rodents. | Neuroscience letters 20010406 |
| The anxiolytic effect of allopregnanolone is associated with gonadal hormonal status in female rats. | European journal of pharmacology 20010406 |
| Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta. | Genes & development 20010401 |
| Antiprogestagen activity of 5H-progesterone metabolites and their analogues, 16alpha,17alpha-cyclohexane-5H-pregnan-3,20-diones. | Bulletin of experimental biology and medicine 20010401 |
| Synergistic protection of allopregnanolone and phenobarbital against maximal electroshock seizures in mice. | Acta pharmacologica Sinica 20010401 |
| Allopregnanolone assays. | The Journal of clinical endocrinology and metabolism 20010301 |
| Neurosteroid withdrawal model of perimenstrual catamenial epilepsy. | Epilepsia 20010301 |
| Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy. | Epilepsia 20010301 |
| Evaluation and comparison of the pharmacokinetic and pharmacodynamic properties of allopregnanolone and pregnanolone at induction of anaesthesia in the male rat. | British journal of anaesthesia 20010301 |
| Self-augmentation effect of male-specific products on sexually differentiated progesterone metabolism in adult male rat liver microsomes. | The Journal of biological chemistry 20010216 |
| A high-performance liquid chromatography-tandem mass spectrometric method for the determination of pharmacokinetics of ganaxolone in rat, monkey, dog and human plasma. | Journal of chromatography. B, Biomedical sciences and applications 20010210 |
| Suppressing aggressive behavior with analogs of allopregnanolone (epalon). | Steroids 20010201 |
| Circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in women with partial epilepsy in the postcritical phase. | Epilepsia 20010201 |
| Alcohol, allopregnanolone and aggression in mice. | Psychopharmacology 20010201 |
| Allopregnanolone, pregnenolone sulfate, and epitestosterone in breast cyst fluid. | Steroids 20010101 |
| Serum allopregnanolone in women with postpartum 'blues'. | Obstetrics and gynecology 20010101 |
| Dehydroepiandrosterone sulphate prevents oxygen-glucose deprivation-induced injury in cerebellar granule cell culture. | Neuroscience 20010101 |
| Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosa. | Psychosomatic medicine 20010101 |
| Application of an enzyme-immunoassay (EIA) for rapid screening of 5 alpha-pregnane-3,20-dione (DHP) in blood plasma of the Asian elephant, Elephas maximus. | Berliner und Munchener tierarztliche Wochenschrift 20010101 |
| Neuroactive steroid levels in patients with generalized anxiety disorder. | The Journal of neuropsychiatry and clinical neurosciences 20010101 |
| Responses to laboratory psychosocial stress in postpartum women. | Psychosomatic medicine 20010101 |
| Physiological roles for the neurosteroid allopregnanolone in the modulation of brain function during pregnancy and parturition. | Progress in brain research 20010101 |
| Stress and neuroactive steroids. | International review of neurobiology 20010101 |
| Neurosteroids in learning and memory processes. | International review of neurobiology 20010101 |
| Neurosteroids and behavior. | International review of neurobiology 20010101 |
| Biosynthesis of neurosteroids and regulation of their synthesis. | International review of neurobiology 20010101 |
| Ethanol and neurosteroid interactions in the brain. | International review of neurobiology 20010101 |
| Clinical implications of circulating neurosteroids. | International review of neurobiology 20010101 |
| Current perspectives on the role of neurosteroids in PMS and depression. | International review of neurobiology 20010101 |
| Two conserved arginines in the extracellular N-terminal domain of the GABA(A) receptor alpha(5) subunit are crucial for receptor function. | Journal of neurochemistry 20001001 |
| Heterogeneity of GABA(A) receptor-mediated responses in the human IMR-32 neuroblastoma cell line. | Journal of neuroscience research 20000515 |
| Anti-seizure effects of progesterone and 3alpha,5alpha-THP in kainic acid and perforant pathway models of epilepsy. | Psychoneuroendocrinology 20000501 |
| Neocortical hyperexcitability after GABA withdrawal in vitro. | Epilepsy research 20000301 |
| Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. | Proceedings of the National Academy of Sciences of the United States of America 19981013 |
| Progesterone withdrawal I: pro-convulsant effects. | Brain research 19981005 |
| Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety. | The Journal of neuroscience : the official journal of the Society for Neuroscience 19980715 |
| Influence of premedication with diazepam or morphine on the induction dose of eltanolone. | Acta anaesthesiologica Scandinavica 19980501 |
| Pentobarbital decreases the gamma-aminobutyric acidA receptor subunit gamma-2 long/short mRNA ratio by a mechanism distinct from receptor occupation. | The Journal of pharmacology and experimental therapeutics 19971001 |
| Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines. | Molecular pharmacology 19970901 |
| Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit. | Nature 19970227 |
| Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors. | Molecular pharmacology 19960201 |
| The neurosteroid tetrahydroprogesterone counteracts corticotropin-releasing hormone-induced anxiety and alters the release and gene expression of corticotropin-releasing hormone in the rat hypothalamus. | Neuroscience 19940901 |
| Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: putative role for allopregnanolone. | The Journal of pharmacology and experimental therapeutics 19940701 |
| A novel allosteric modulatory site on the GABAA receptor beta subunit. | Neuron 19940401 |
| 5 alpha-Pregnan-3 alpha-ol-20-one blocks nicotine-induced seizures and enhances paired-pulse inhibition. | European journal of pharmacology 19900828 |