2,2',4,4'-Tetrabromodiphenyl ether
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Studies on the interaction of BDE-47 and BDE-209 with acetylcholinesterase (AChE) based on the neurotoxicity through fluorescence, UV-vis spectra, and molecular docking. | Toxicology letters 20180501 |
In utero and lactational exposure to BDE-47 promotes obesity development in mouse offspring fed a high-fat diet: impaired lipid metabolism and intestinal dysbiosis. | Archives of toxicology 20180501 |
Organophosphate Flame-Retardants Alter Adult Mouse Homeostasis and Gene Expression in a Sex-Dependent Manner Potentially Through Interactions With ERα. | Toxicological sciences : an official journal of the Society of Toxicology 20180301 |
Effects of 2,2',4,4'-tetrabromodiphenyl ether on neurobehavior and memory change and bcl-2, c-fos, grin1b and lingo1b gene expression in male zebrafish (Danio rerio). | Toxicology and applied pharmacology 20171015 |
Perinatal exposure to 2,2',4'4' -Tetrabromodiphenyl ether induces testicular toxicity in adult rats. | Toxicology 20170815 |
High-fat diet aggravates 2,2',4,4'-tetrabromodiphenyl ether-inhibited testosterone production via DAX-1 in Leydig cells in rats. | Toxicology and applied pharmacology 20170515 |
The flame retardant 2,2',4,4'-Tetrabromodiphenyl ether enhances the expression of corticotropin-releasing hormone in the placental cell model JEG-3. | Chemosphere 20170501 |
Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate. | Environmental science & technology 20170404 |
Differences in the mechanisms of action of BDE-47 and its metabolites on OVCAR-3 and MCF-7 cell apoptosis. | Journal of applied toxicology : JAT 20170401 |
Development of a screening approach to detect thyroid disrupting chemicals that inhibit the human sodium iodide symporter (NIS). | Toxicology in vitro : an international journal published in association with BIBRA 20170401 |
Endocrine disrupting compounds modulates adiponectin secretion, expression of its receptors and action on steroidogenesis in ovarian follicle. | Reproductive toxicology (Elmsford, N.Y.) 20170401 |
Assessing the identity and expression level of the cytochrome P450 20A1 (CYP20A1) gene in the BPA-, BDE-47, and WAF-exposed copepods Tigriopus japonicus and Paracyclopina nana. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20170301 |
Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure. | Toxicological sciences : an official journal of the Society of Toxicology 20170101 |
Different mechanisms of action of 2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) and its metabolites (5-OH-BDE-47 and 6-OH-BDE-47) on cell proliferation in OVCAR-3 ovarian cancer cells and MCF-7 breast cancer cells. | Journal of applied toxicology : JAT 20161201 |
Evaluation of Polybrominated Diphenyl Ether Toxicity on HepG2 Cells - Hexabrominated Congener (BDE-154) Is Less Toxic than Tetrabrominated Congener (BDE-47). | Basic & clinical pharmacology & toxicology 20161101 |
Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro. | Environmental science & technology 20161004 |
BDE-99, but not BDE-47, is a transient aryl hydrocarbon receptor agonist in zebrafish liver cells. | Toxicology and applied pharmacology 20160815 |
Impact of molt-disrupting BDE-47 on epidermal ecdysteroid signaling in the blue crab, Callinectes sapidus, in vitro. | Aquatic toxicology (Amsterdam, Netherlands) 20160801 |
Association of Environmental Toxins With Amyotrophic Lateral Sclerosis. | JAMA neurology 20160701 |
Hazards of low dose flame-retardants (BDE-47 and BDE-32): Influence on transcriptome regulation and cell death in human liver cells. | Journal of hazardous materials 20160505 |
Organophosphate Flame Retardants Act as Endocrine-Disrupting Chemicals in MA-10 Mouse Tumor Leydig Cells. | Toxicological sciences : an official journal of the Society of Toxicology 20160401 |
Effect of triclosan, triclocarban, 2,2',4,4'-tetrabromodiphenyl ether, and bisphenol A on the iodide uptake, thyroid peroxidase activity, and expression of genes involved in thyroid hormone synthesis. | Toxicology in vitro : an international journal published in association with BIBRA 20160401 |
Do persistent organic pollutants interact with the stress response? Individual compounds, and their mixtures, interaction with the glucocorticoid receptor. | Toxicology letters 20160122 |
Environmental exposure to BDE47 is associated with increased diabetes prevalence: Evidence from community-based case-control studies and an animal experiment. | Scientific reports 20160101 |
Protective effect of (±)α-tocopherol on brominated diphenyl ether-47-stimulated prostaglandin pathways in human extravillous trophoblasts in vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20151001 |
Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust. | Environmental science & technology 20150818 |
Disruption of type 2 iodothyronine deiodinase activity in cultured human glial cells by polybrominated diphenyl ethers. | Chemical research in toxicology 20150615 |
Effect of omega-3 fatty acid oxidation products on the cellular and mitochondrial toxicity of BDE 47. | Toxicology in vitro : an international journal published in association with BIBRA 20150601 |
Steroid hormone related effects of marine persistent organic pollutants in human H295R adrenocortical carcinoma cells. | Toxicology in vitro : an international journal published in association with BIBRA 20150601 |
Multiple biomarkers of the cytotoxicity induced by BDE-47 in human embryonic kidney cells. | Chemosphere 20150501 |
The brominated flame retardant BDE-47 causes oxidative stress and apoptotic cell death in vitro and in vivo in mice. | Neurotoxicology 20150501 |
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | Toxicology and applied pharmacology 20150401 |
Troxerutin inhibits 2,2',4,4'-tetrabromodiphenyl ether (BDE-47)-induced hepatocyte apoptosis by restoring proteasome function. | Toxicology letters 20150318 |
Epigenetic effects of low perinatal doses of flame retardant BDE-47 on mitochondrial and nuclear genes in rat offspring. | Toxicology 20150203 |
Bioaccumulation, biotransformation, and toxicity of BDE-47, 6-OH-BDE-47, and 6-MeO-BDE-47 in early life-stages of zebrafish (Danio rerio). | Environmental science & technology 20150203 |
Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust. | Environmental health perspectives 20150201 |
In vitro immune toxicity of polybrominated diphenyl ethers on murine peritoneal macrophages: apoptosis and immune cell dysfunction. | Chemosphere 20150201 |
Evaluation of the toxic effects of brominated compounds (BDE-47, 99, 209, TBBPA) and bisphenol A (BPA) using a zebrafish liver cell line, ZFL. | Aquatic toxicology (Amsterdam, Netherlands) 20150201 |
High-throughput RNA sequencing reveals the effects of 2,2',4,4' -tetrabromodiphenyl ether on retina and bone development of zebrafish larvae. | BMC genomics 20150101 |
Aberrant 5'-CpG Methylation of Cord Blood TNFα Associated with Maternal Exposure to Polybrominated Diphenyl Ethers. | PloS one 20150101 |
Protective effect of nuclear factor E2-related factor 2 on inflammatory cytokine response to brominated diphenyl ether-47 in the HTR-8/SVneo human first trimester extravillous trophoblast cell line. | Toxicology and applied pharmacology 20141115 |
Different action of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) and its hydroxylated metabolites on ERα and ERβ gene and protein expression. | Toxicology letters 20140817 |
Biosynthesis of polybrominated aromatic organic compounds by marine bacteria. | Nature chemical biology 20140801 |
Cross-omics gene and protein expression profiling in juvenile female mice highlights disruption of calcium and zinc signalling in the brain following dietary exposure to CB-153, BDE-47, HBCD or TCDD. | Toxicology 20140703 |
Identification and mRNA expression of two 17β-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals. | Environmental toxicology and pharmacology 20140501 |
PBDE: structure-activity studies for the inhibition of hepatitis C virus NS3 helicase. | Molecules (Basel, Switzerland) 20140402 |
Decabrominated diphenyl ether (BDE-209) and/or BDE-47 exposure alters protein expression in purified neural stem/progenitor cells determined by proteomics analysis. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20140401 |
Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47. | Environmental science & technology 20140401 |
Toxicity assessment of air-delivered particle-bound polybrominated diphenyl ethers. | Toxicology 20140320 |
Heavy metal influence on BDE-47 uptake in the human KERTr keratinocyte cell line. | Environmental toxicology 20140301 |
Flame retardant BDE-47 effectively activates nuclear receptor CAR in human primary hepatocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20140201 |
Involvement of reactive oxygen species in brominated diphenyl ether-47-induced inflammatory cytokine release from human extravillous trophoblasts in vitro. | Toxicology and applied pharmacology 20140115 |
Case-control study of breast cancer and exposure to synthetic environmental chemicals among Alaska Native women. | International journal of circumpolar health 20140101 |
Effects of perchlorate on BDE-47-induced alteration thyroid hormone and gene expression of in the hypothalamus-pituitary-thyroid axis in zebrafish larvae. | Environmental toxicology and pharmacology 20131101 |
Proteomic and metabolomic analysis of earthworm Eisenia fetida exposed to different concentrations of 2,2',4,4'-tetrabromodiphenyl ether. | Journal of proteomics 20131008 |
Mimicking of estradiol binding by flame retardants and their metabolites: a crystallographic analysis. | Environmental health perspectives 20131001 |
Gender-specific transcriptional profiling of marine medaka (Oryzias melastigma) liver upon BDE-47 exposure. | Comparative biochemistry and physiology. Part D, Genomics & proteomics 20130901 |
Structure-dependent activities of hydroxylated polybrominated diphenyl ethers on human estrogen receptor. | Toxicology 20130705 |
A hydroxylated metabolite of flame-retardant PBDE-47 decreases the survival, proliferation, and neuronal differentiation of primary cultured adult neural stem cells and interferes with signaling of ERK5 MAP kinase and neurotrophin 3. | Toxicological sciences : an official journal of the Society of Toxicology 20130701 |
Biotransformation of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) by human liver microsomes: identification of cytochrome P450 2B6 as the major enzyme involved. | Chemical research in toxicology 20130520 |
Hydroxylated polybrominated diphenyl ethers exhibit different activities on thyroid hormone receptors depending on their degree of bromination. | Toxicology and applied pharmacology 20130501 |
Biotransformation of BDE-47 to potentially toxic metabolites is predominantly mediated by human CYP2B6. | Environmental health perspectives 20130401 |
Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays. | Environmental science & technology 20130319 |
The 2,2',4,4'-tetrabromodiphenyl ether hydroxylated metabolites 5-OH-BDE-47 and 6-OH-BDE-47 stimulate estradiol secretion in the ovary by activating aromatase expression. | Toxicology 20130308 |
Cultured human peripheral blood mononuclear cells alter their gene expression when challenged with endocrine-disrupting chemicals. | Toxicology 20130107 |
2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) decreases progesterone synthesis through cAMP-PKA pathway and P450scc downregulation in mouse Leydig tumor cells. | Toxicology 20121208 |
Accumulation and biotransformation of BDE-47 by zebrafish larvae and teratogenicity and expression of genes along the hypothalamus-pituitary-thyroid axis. | Environmental science & technology 20121204 |
Activation of the enzymes of phase I (CYP2B1/2) and phase II (SULT1A and COMT) metabolism by 2,2',4,4'-tetrabromodiphenyl ether (BDE47) in the pig ovary. | Reproductive toxicology (Elmsford, N.Y.) 20121101 |
New approaches to assess the transthyretin binding capacity of bioactivated thyroid hormone disruptors. | Toxicological sciences : an official journal of the Society of Toxicology 20121101 |
Toxic effects of two brominated flame retardants BDE-47 and BDE-183 on the survival and protein expression of the tubificid Monopylephorus limosus. | Ecotoxicology and environmental safety 20121001 |
BDE-47 disrupts axonal growth and motor behavior in developing zebrafish. | Aquatic toxicology (Amsterdam, Netherlands) 20120915 |
Biodegradation of triclosan by a wastewater microorganism. | Water research 20120901 |
Distribution of polybrominated diphenyl ethers in the surface sediments of the Taihu Lake, China. | Chemosphere 20120901 |
Determination of polybrominated diphenyl ethers in human semen. | Environment international 20120701 |
Hydroxylated PBDEs induce developmental arrest in zebrafish. | Toxicology and applied pharmacology 20120701 |
Improved debromination of polybrominated diphenyl ethers by bimetallic iron-silver nanoparticles coupled with microwave energy. | The Science of the total environment 20120701 |
The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cells in vitro. | Toxicology letters 20120620 |
Metabolism of polybrominated diphenyl ethers and tetrabromobisphenol A by fish liver subcellular fractions in vitro. | Aquatic toxicology (Amsterdam, Netherlands) 20120615 |
Long-lived epigenetic interactions between perinatal PBDE exposure and Mecp2308 mutation. | Human molecular genetics 20120601 |
Molecular cloning and characterization of estrogen receptor gene in the scallop Chlamys farreri: expression profiles in response to endocrine disrupting chemicals. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120601 |
Cyto-genotoxic effects induced by three brominated diphenyl ether congeners on the freshwater mussel Dreissena polymorpha. | Ecotoxicology and environmental safety 20120501 |
Heating of BDE-209 and BDE-47 in plant oil in presence of o,p'-DDT or iron(III) chloride can produce monochloro-polybromo diphenyl ethers. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501 |
Sensitive immunoassay detection of multiple environmental chemicals on protein microarrays using DNA/dye conjugate as a fluorescent label. | Journal of environmental monitoring : JEM 20120501 |
Computational toxicological investigation on the mechanism and pathways of xenobiotics metabolized by cytochrome P450: a case of BDE-47. | Environmental science & technology 20120501 |
Emerging and historical brominated flame retardants in peregrine falcon (Falco peregrinus) eggs from Canada and Spain. | Environment international 20120401 |
Polybrominated diphenyl ethers (PBDEs) in human serum from Southeast China. | Ecotoxicology and environmental safety 20120401 |
BDE-47 sorption and desorption to soil matrix in single- and binary-solute systems. | Chemosphere 20120401 |
Desorption behaviors of BDE-28 and BDE-47 from natural soils with different organic carbon contents. | Environmental pollution (Barking, Essex : 1987) 20120401 |
The hormesis effect of BDE-47 in HepG2 cells and the potential molecular mechanism. | Toxicology letters 20120307 |
Influence of prenatal organohalogen levels on infant male sexual development: sex hormone levels, testes volume and penile length. | Human reproduction (Oxford, England) 20120301 |
[Microbial degradation of 2, 2', 4, 4'-tetrabrominated diphenyl ether under anaerobic condition]. | Huan jing ke xue= Huanjing kexue 20120301 |
Disruption of the hypothalamic-pituitary-thyroid axis in zebrafish embryo-larvae following waterborne exposure to BDE-47, TBBPA and BPA. | Aquatic toxicology (Amsterdam, Netherlands) 20120201 |
Levels of dechlorane plus and polybrominated diphenylethers in human milk in two Canadian cities. | Environment international 20120201 |
Spatial learning and memory deficit of low level polybrominated diphenyl ethers-47 in male adult rat is modulated by intracellular glutamate receptors. | The Journal of toxicological sciences 20120101 |
Evaluation of DNA damage induced by 2 polybrominated diphenyl ether flame retardants (BDE-47 and BDE-209) in SK-N-MC cells. | International journal of toxicology 20120101 |
Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice. | Toxicology and applied pharmacology 20111115 |
Multiplex screening of persistent organic pollutants in fish using spectrally encoded microspheres. | Analytical chemistry 20111115 |
The cytotoxic effects of synthetic 6-hydroxylated and 6-methoxylated polybrominated diphenyl ether 47 (BDE47). | Environmental toxicology 20111101 |
Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. | Toxicology and applied pharmacology 20111101 |
Effects of developmental exposure to polychlorinated biphenyls and/or polybrominated diphenyl ethers on cochlear function. | Toxicological sciences : an official journal of the Society of Toxicology 20111101 |
Legacy and contemporary persistent organic pollutants in North Pacific albatross. | Environmental toxicology and chemistry 20111101 |
Congener-specific action of PBDEs on steroid secretion, CYP17, 17β-HSD and CYP19 activity and protein expression in porcine ovarian follicles. | Toxicology letters 20111030 |
Cerebral gene expression and neurobehavioural development after perinatal exposure to an environmentally relevant polybrominated diphenylether (BDE47). | Cell biology and toxicology 20111001 |
Sorption isotherms of brominated diphenyl ethers on natural soils with different organic carbon fractions. | Environmental pollution (Barking, Essex : 1987) 20111001 |
Hepatic in vitro toxicity assessment of PBDE congeners BDE47, BDE153 and BDE154 in Atlantic salmon (Salmo salar L.). | Aquatic toxicology (Amsterdam, Netherlands) 20111001 |
Development of a monoclonal antibody-based, congener-specific and solvent-tolerable direct enzyme-linked immunosorbent assay for the detection of 2,2',4,4'-tetrabromodiphenyl ether in environmental samples. | Analytical and bioanalytical chemistry 20111001 |
Two-stage reduction/subsequent oxidation treatment of 2,2',4,4'-tetrabromodiphenyl ether in aqueous solutions: kinetic, pathway and toxicity. | Journal of hazardous materials 20110915 |
Comparative oxidative metabolism of BDE-47 and BDE-99 by rat hepatic microsomes. | Toxicological sciences : an official journal of the Society of Toxicology 20110901 |
Association between type 2 diabetes and exposure to persistent organic pollutants. | Diabetes care 20110901 |
Effect of brominated flame retardant BDE-47 on androgen production of adult rat Leydig cells. | Toxicology letters 20110828 |
The involvement of ROS overproduction and mitochondrial dysfunction in PBDE-47-induced apoptosis on Jurkat cells. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110701 |
Bioavailability of hydrophobic organic contaminants in sediment with different particle-size distributions. | Archives of environmental contamination and toxicology 20110701 |
Delayed response in the rat frontal lobe transcriptome to perinatal exposure to the flame retardant BDE-47. | Journal of applied toxicology : JAT 20110701 |
Spatial trends of polybrominated diphenyl ethers in Canadian fish and implications for long-term monitoring. | Environmental toxicology and chemistry 20110701 |
Residues of PBDEs in northeastern Pacific marine fish: evidence for spatial and temporal trends. | Environmental toxicology and chemistry 20110601 |
Interaction of PFOS and BDE-47 co-exposure on thyroid hormone levels and TH-related gene and protein expression in developing rat brains. | Toxicological sciences : an official journal of the Society of Toxicology 20110601 |
Bioaccumulation and maternal transfer of PBDE 47 in the marine medaka (Oryzias melastigma) following dietary exposure. | Aquatic toxicology (Amsterdam, Netherlands) 20110601 |
A dynamic multimedia environmental and bioaccumulation model for brominated flame retardants in Lake Huron and Lake Erie, USA. | Environmental toxicology and chemistry 20110501 |
Polybrominated diphenyl ethers and sperm quality. | Reproductive toxicology (Elmsford, N.Y.) 20110501 |
Toxic effect of PBDE-47 on thyroid development, learning, and memory, and the interaction between PBDE-47 and PCB153 that enhances toxicity in rats. | Toxicology and industrial health 20110401 |
Para- and ortho-substitutions are key determinants of polybrominated diphenyl ether activity toward ryanodine receptors and neurotoxicity. | Environmental health perspectives 20110401 |
Neurochemical changes following a single dose of polybrominated diphenyl ether 47 in mice. | Drug and chemical toxicology 20110401 |
Does 2,2',4,4'-tetrabromodiphenyl ether interact directly with thyroid receptor? | Journal of applied toxicology : JAT 20110301 |
Can biotransformation of BDE-209 in lake trout cause bioaccumulation of more toxic, lower-brominated PBDEs (BDE-47, -99) over the long term? | Environment international 20110101 |
Dietary exposure of juvenile common sole (Solea solea L.) to polybrominated diphenyl ethers (PBDEs): Part 1. Bioaccumulation and elimination kinetics of individual congeners and their debrominated metabolites. | Environmental pollution (Barking, Essex : 1987) 20110101 |
Polybrominated diphenyl ethers in relation to autism and developmental delay: a case-control study. | Environmental health : a global access science source 20110101 |
Bioaccumulation and behavioral effects of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in perinatally exposed mice. | Neurotoxicology and teratology 20110101 |
In vitro profiling of endocrine disrupting potency of 2,2',4,4'-tetrabromodiphenyl ether (BDE47) and related hydroxylated analogs (HO-PBDEs). | Marine pollution bulletin 20110101 |
Cytotoxic effects and oxidative stress response of six PBDE metabolites on human L02 cells. | Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20110101 |
Cytogenotoxicity induced by PBDE-47 combined with PCB153 treatment in SH-SY5Y cells. | Environmental toxicology 20101201 |
Interconversion of hydroxylated and methoxylated polybrominated diphenyl ethers in Japanese medaka. | Environmental science & technology 20101115 |
Structure-based investigation on the binding interaction of hydroxylated polybrominated diphenyl ethers with thyroxine transport proteins. | Toxicology 20101109 |
Partitioning of tetra- and pentabromo diphenyl ether and benzo[a]pyrene among water and dissolved and particulate organic carbon along a salinity gradient in coastal waters. | Environmental toxicology and chemistry 20101101 |
Vibrational spectroscopic investigation and DFT studies on 2,2',4,4'-tetrabromodiphenyl ether. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20101015 |
Polybrominated diphenyl ethers and arylhydrocarbon receptor agonists: Different toxicity and target gene expression. | Toxicology letters 20101005 |
Sorption kinetic characteristics of polybrominated diphenyl ethers on natural soils. | Environmental pollution (Barking, Essex : 1987) 20100901 |
Metabolism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in chickens. | Journal of agricultural and food chemistry 20100811 |
Chronic exposure of 2,2',4,4'-tetrabromodiphenyl ether (PBDE-47) alters locomotion behavior in juvenile zebrafish (Danio rerio). | Aquatic toxicology (Amsterdam, Netherlands) 20100715 |
Cytotoxicity and apoptosis induction on RTG-2 cells of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) and decabrominated diphenyl ether (BDE-209). | Toxicology in vitro : an international journal published in association with BIBRA 20100601 |
Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters. | Toxicological sciences : an official journal of the Society of Toxicology 20100601 |
Changes in mitogen-activated protein kinase in cerebellar granule neurons by polybrominated diphenyl ethers and polychlorinated biphenyls. | Toxicology and applied pharmacology 20100515 |
Thirty year monitoring of PCBs, organochlorine pesticides and tetrabromodiphenylether in eel from The Netherlands. | Environmental pollution (Barking, Essex : 1987) 20100501 |
Flow cytometric analysis of BDE 47 mediated injury to rainbow trout gill epithelial cells. | Aquatic toxicology (Amsterdam, Netherlands) 20100401 |
Bromination pattern of hydroxylated metabolites of BDE-47 affects their potency to release calcium from intracellular stores in PC12 cells. | Environmental health perspectives 20100401 |
Mixture of dominant PBDE congeners (BDE-47, -99, -100 and -209) at levels noted in human blood dramatically enhances progesterone secretion by ovarian follicles. | Endocrine regulations 20100401 |
Growth and transcriptional effect of dietary 2,2',4,4'-tetrabromodiphenyl ether (PBDE-47) exposure in developing zebrafish (Danio rerio). | Ecotoxicology and environmental safety 20100301 |
Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells. | Toxicology in vitro : an international journal published in association with BIBRA 20100201 |
Global gene expression analysis in the livers of rat offspring perinatally exposed to low doses of 2,2',4,4'-tetrabromodiphenyl ether. | Environmental health perspectives 20100101 |
Placental transfer of the polybrominated diphenyl ethers BDE-47, BDE-99 and BDE-209 in a human placenta perfusion system: an experimental study. | Environmental health : a global access science source 20100101 |
Prenatal exposure to organohalogens, including brominated flame retardants, influences motor, cognitive, and behavioral performance at school age. | Environmental health perspectives 20091201 |
Mechanisms underlying the developmental neurotoxic effect of PBDE-47 and the enhanced toxicity associated with its combination with PCB153 in rats. | Neurotoxicology 20091101 |
Human liver microsome-mediated metabolism of brominated diphenyl ethers 47, 99, and 153 and identification of their major metabolites. | Chemical research in toxicology 20091101 |
Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47. | Environmental science & technology 20091015 |
Accessibility of polybrominated diphenyl ether congeners in aging soil. | Journal of environmental monitoring : JEM 20090901 |
[Effects of PCB153 on oxidative stress and 8-OHdG content induced by PBDE-47 in human neuroblastoma cells in vitro]. | Wei sheng yan jiu = Journal of hygiene research 20090901 |
[Effects and toxicity mechanism of 2,2',4,4'-tetrabrominated diphenyl ethers on the homeostasis of thyroid hormone system in C57BL/6 mice]. | Wei sheng yan jiu = Journal of hygiene research 20090901 |
Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells. | Environmental health perspectives 20090801 |
Perinatal exposure to low-dose 2,2',4,4'-tetrabromodiphenyl ether affects growth in rat offspring: what is the role of IGF-1? | Toxicology 20090616 |
In vitro hepatic metabolism of 2,2',4,4',5-pentabromodiphenyl ether (BDE 99) in Chinook salmon (Onchorhynchus tshawytscha). | Aquatic toxicology (Amsterdam, Netherlands) 20090517 |
Examining the role of temperature and sediment-chemical contact time on desorption and bioavailability of sediment-associated tetrabromo diphenyl ether and benzo(a)pyrene. | Ecotoxicology and environmental safety 20090501 |
Lethal and sublethal effects of simvastatin, irgarol, and PBDE-47 on the estuarine fish, Fundulus heteroclitus. | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20090501 |
Transcriptional effects of nonylphenol, bisphenol A and PBDE-47 in liver of juvenile Atlantic cod (Gadus morhua). | Chemosphere 20090401 |
Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders. | Journal of neuroimmunology 20090331 |
Biomagnification of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls in a highly contaminated freshwater food web from South China. | Environmental pollution (Barking, Essex : 1987) 20090301 |
Distribution of polybrominated diphenyl ethers in breast milk from North China: implication of exposure pathways. | Chemosphere 20090301 |
Cytotoxicity and gene expression profiling of two hydroxylated polybrominated diphenyl ethers in human H295R adrenocortical carcinoma cells. | Toxicology letters 20090225 |
Recombinant transthyretin purification and competitive binding with organohalogen compounds in two gull species (Larus argentatus and Larus hyperboreus). | Toxicological sciences : an official journal of the Society of Toxicology 20090201 |
Influence of PCB153 on oxidative DNA damage and DNA repair-related gene expression induced by PBDE-47 in human neuroblastoma cells in vitro. | Toxicological sciences : an official journal of the Society of Toxicology 20090101 |
Mechanism of the neurotoxic effect of PBDE-47 and interaction of PBDE-47 and PCB153 in enhancing toxicity in SH-SY5Y cells. | Neurotoxicology 20090101 |
Thyroid disruption by low-dose BDE-47 in prenatally exposed lambs. | Neonatology 20090101 |
Site-specific impacts on gene expression and behavior in fathead minnows (Pimephales promelas) exposed in situ to streams adjacent to sewage treatment plants. | BMC bioinformatics 20090101 |
Polymeric brominated flame retardants: are they a relevant source of emerging brominated aromatic compounds in the environment? | Environmental science & technology 20081215 |
Dietary exposure to 2,2',4,4'-tetrabromodiphenyl ether (PBDE-47) alters thyroid status and thyroid hormone-regulated gene transcription in the pituitary and brain. | Environmental health perspectives 20081201 |
Photodegradation of 2,2',4,4'-tetrabromodiphenyl ether in nonionic surfactant solutions. | Chemosphere 20081101 |
Airborne PBDEs in specialized occupational settings, houses and outdoor urban areas in Greece. | Environmental pollution (Barking, Essex : 1987) 20080901 |
A technical mixture of 2,2',4,4'-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity. | Chemosphere 20080901 |
[Effects of PCB153 on DNA damage and DNA repair-related genes expressions induced by PBDE-47 in human neuroblastoma cells in vitro]. | Wei sheng yan jiu = Journal of hygiene research 20080901 |
Concentration of polybrominated diphenyl ethers (PBDEs) in household dust from various countries. | Chemosphere 20080801 |
Multixenobiotic resistance, acetyl-choline esterase activity and total oxyradical scavenging capacity of the Arctic spider crab, Hyasaraneus, following exposure to bisphenol A, tetra bromo diphenyl ether and diallyl phthalate. | Marine pollution bulletin 20080801 |
Determination of polybromodiphenyl ethers (PBDEs) in milk cream by gas chromatography-mass spectrometry. | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080801 |
Toxicity and physiological effects of brominated flame retardant PBDE-47 on two life stages of grass shrimp, Palaemonetes pugio. | The Science of the total environment 20080725 |
Spatial trends of polybrominated diphenyl ethers in avian species: utilization of stored samples in the Environmental Specimen Bank of Ehime University (es-Bank). | Environmental pollution (Barking, Essex : 1987) 20080701 |
Effect of parental exposure to trenbolone and the brominated flame retardant BDE-47 on fertility in rainbow trout (Oncorhynchus mykiss). | Marine environmental research 20080701 |
Comparative oxygen radical formation and toxicity of BDE 47 in rainbow trout cell lines. | Marine environmental research 20080701 |
Biomonitoring of polybrominated diphenyl ether (PBDE) pollution: a field study. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080701 |
Hydroxylation increases the neurotoxic potential of BDE-47 to affect exocytosis and calcium homeostasis in PC12 cells. | Environmental health perspectives 20080501 |
Serum concentrations of neutral and phenolic organohalogens in pregnant women and some of their infants in The Netherlands. | Environmental science & technology 20080501 |
Atmospheric concentrations and phase partitioning of polybrominated diphenyl ethers (PBDEs) in Izmir, Turkey. | Chemosphere 20080401 |
Gene expression profiles in rainbow trout, Onchorynchus mykiss, exposed to a simple chemical mixture. | Toxicological sciences : an official journal of the Society of Toxicology 20080301 |
In utero and lactational exposures to low doses of polybrominated diphenyl ether-47 alter the reproductive system and thyroid gland of female rat offspring. | Environmental health perspectives 20080301 |
Microarray analysis reveals a mechanism of phenolic polybrominated diphenylether toxicity in zebrafish. | Environmental science & technology 20080301 |
Inhibition of human placental aromatase activity by hydroxylated polybrominated diphenyl ethers (OH-PBDEs). | Toxicology and applied pharmacology 20080215 |
Effects of 20 PBDE metabolites on steroidogenesis in the H295R cell line. | Toxicology letters 20080215 |
Reductive debromination of polybrominated diphenyl ethers in anaerobic sediment and a biomimetic system. | Environmental science & technology 20080215 |
Serum concentrations of polybrominated diphenyl ethers (PBDEs) and polybrominated biphenyl (PBB) in the United States population: 2003-2004. | Environmental science & technology 20080215 |
Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. | Toxicology and applied pharmacology 20080201 |
Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47). | Molecular nutrition & food research 20080201 |
Probabilistic intake assessment of polybrominated diphenyl ethers and omega-3 fatty acids through fish consumption. | Molecular nutrition & food research 20080201 |
Consumption of fish from a contaminated lake strongly affects the concentrations of polybrominated diphenyl ethers and hexabromocyclododecane in serum. | Molecular nutrition & food research 20080201 |
Temporal trends of polybrominated diphenyl ethers and hexabromocyclododecane in milk from Stockholm mothers, 1980-2004. | Molecular nutrition & food research 20080201 |
Dietary exposure to brominated flame retardants correlates with male blood levels in a selected group of Norwegians with a wide range of seafood consumption. | Molecular nutrition & food research 20080201 |
Determination of brominated flame retardants and brominated dioxins in fish collected from three regions of Japan. | Molecular nutrition & food research 20080201 |
Effects of PBDE-47 on cytotoxicity and genotoxicity in human neuroblastoma cells in vitro. | Mutation research 20080108 |
Geographical distribution and accumulation features of PBDEs in human breast milk from Indonesia. | Environmental pollution (Barking, Essex : 1987) 20080101 |
The role of mitochondrial and oxidative injury in BDE 47 toxicity to human fetal liver hematopoietic stem cells. | Toxicological sciences : an official journal of the Society of Toxicology 20080101 |
PBDE-47-induced oxidative stress, DNA damage and apoptosis in primary cultured rat hippocampal neurons. | Neurotoxicology 20080101 |
Acute postnatal exposure to brominated diphenylether 47 delays neuromotor ontogeny and alters motor activity in mice. | Neurotoxicology and teratology 20080101 |
Lack of alterations in thyroid hormones following exposure to polybrominated diphenyl ether 47 during a period of rapid brain development in mice. | Drug and chemical toxicology 20080101 |
A cohort study of in utero polychlorinated biphenyl (PCB) exposures in relation to secondary sex ratio. | Environmental health : a global access science source 20080101 |
Facing the challenge of data transfer from animal models to humans: the case of persistent organohalogens. | Environmental health : a global access science source 20080101 |
Fish as biomonitors of polybrominated diphenyl ethers and hexabromocyclododecane in Czech aquatic ecosystems: pollution of the Elbe River basin. | Environmental health perspectives 20071201 |
Debromination of polybrominated diphenyl ether-99 (BDE-99) in carp (Cyprinus carpio) microflora and microsomes. | Chemosphere 20071001 |
Plasma concentrations of selected organobromine compounds and polychlorinated biphenyls in postmenopausal women of Québec, Canada. | Environmental health perspectives 20071001 |
Flame retardants in placenta and breast milk and cryptorchidism in newborn boys. | Environmental health perspectives 20071001 |
Distribution of BDE-99 and effects on metamorphosis of BDE-99 and -47 after oral exposure in Xenopus tropicalis. | Aquatic toxicology (Amsterdam, Netherlands) 20070815 |
Disruption of thyroid hormone binding to sea bream recombinant transthyretin by ioxinyl and polybrominated diphenyl ethers. | Chemosphere 20070801 |
Food web-specific biomagnification of persistent organic pollutants. | Science (New York, N.Y.) 20070713 |
Polybrominated diphenyl ethers and ortho-substituted polychlorinated biphenyls as neuroendocrine disruptors of vasopressin release: effects during physiological activation in vitro and structure-activity relationships. | Toxicological sciences : an official journal of the Society of Toxicology 20070701 |
Measurement of polybrominated diphenyl ethers and metabolites in mouse plasma after exposure to a commercial pentabromodiphenyl ether mixture. | Environmental health perspectives 20070701 |
Tetrabromodiphenyl ether (BDE 47) evokes estrogenicity and calbindin-D9k expression through an estrogen receptor-mediated pathway in the uterus of immature rats. | Toxicological sciences : an official journal of the Society of Toxicology 20070601 |
Neonatal exposure to brominated flame retardant BDE-47 reduces long-term potentiation and postsynaptic protein levels in mouse hippocampus. | Environmental health perspectives 20070601 |
Neural defects and cardiac arrhythmia in fish larvae following embryonic exposure to 2,2',4,4'-tetrabromodiphenyl ether (PBDE 47). | Aquatic toxicology (Amsterdam, Netherlands) 20070531 |
Silica gel as a particulate carrier of poorly water-soluble substances in aquatic toxicity testing. | Aquatic toxicology (Amsterdam, Netherlands) 20070531 |
The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators. | Toxicological sciences : an official journal of the Society of Toxicology 20070501 |
[Effects of 2,2', 4,4' -tetrabromodiphenyl ethers on oxidative stress and DNA damage in SH-SY5Y cells]. | Wei sheng yan jiu = Journal of hygiene research 20070501 |
Physicochemical properties of selected polybrominated diphenyl ethers and extension of the UNIFAC model to brominated aromatic compounds. | Chemosphere 20070401 |
Plasma PBDE and thyroxine levels in rats exposed to Bromkal or BDE-47. | Chemosphere 20070401 |
Dehalogenation of polychlorinated biphenyls and polybrominated diphenyl ethers using a hybrid bioinorganic catalyst. | Journal of environmental monitoring : JEM 20070401 |
Congener distribution of polybrominated diphenyl ethers in feral carp (Cyprinus carpio) from the Llobregat River, Spain. | Environmental pollution (Barking, Essex : 1987) 20070301 |
[Effects of PBDE-47 on oxidative stress and apoptosis in SH-SY5Y cell]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20070301 |
Indoor organophosphate and polybrominated flame retardants in Tokyo. | Indoor air 20070201 |
Bioaccumulation and biotransformation of 61 polychlorinated biphenyl and four polybrominated diphenyl ether congeners in juvenile American kestrels (Falco sparverius). | Environmental toxicology and chemistry 20070201 |
Bioavailability and mass balance studies of a commercial pentabromodiphenyl ether mixture in male Sprague-Dawley rats. | Chemosphere 20070101 |
Polybrominated diphenyl ether levels in the blood of pregnant women living in an agricultural community in California. | Environmental health perspectives 20070101 |
Toxicokinetics of polybrominated diphenyl ether congeners 47, 99, 100, and 153 in mice. | Toxicological sciences : an official journal of the Society of Toxicology 20061101 |
In vitro effects of brominated flame retardants and metabolites on CYP17 catalytic activity: a novel mechanism of action? | Toxicology and applied pharmacology 20061015 |
Children show highest levels of polybrominated diphenyl ethers in a California family of four: a case study. | Environmental health perspectives 20061001 |
Effects of xenobiotics and steroids on renal and hepatic estrogen metabolism in lake trout. | General and comparative endocrinology 20060901 |
Nonabsorbable dietary fat enhances disposal of 2,2',4,4'-tetrabromodiphenyl ether in rats through interruption of enterohepatic circulation. | Journal of agricultural and food chemistry 20060823 |
Antagonism of TCDD-induced ethoxyresorufin-O-deethylation activity by polybrominated diphenyl ethers (PBDEs) in primary cynomolgus monkey (Macaca fascicularis) hepatocytes. | Toxicology letters 20060701 |
In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. | Toxicological sciences : an official journal of the Society of Toxicology 20060701 |
Interactions of polybrominated diphenyl ethers with the aryl hydrocarbon receptor pathway. | Toxicological sciences : an official journal of the Society of Toxicology 20060701 |
Identification of proteomic signatures of exposure to marine pollutants in mussels (Mytilus edulis). | Molecular & cellular proteomics : MCP 20060701 |
Preliminary study of responses in mussel (Mytilus edilus) exposed to bisphenol A, diallyl phthalate and tetrabromodiphenyl ether. | Aquatic toxicology (Amsterdam, Netherlands) 20060601 |
Expression of cytoskeletal proteins, cross-reacting with anti-CYP1A, in Mytilus sp. exposed to organic contaminants. | Aquatic toxicology (Amsterdam, Netherlands) 20060601 |
Induction of micronuclei and other nuclear abnormalities in mussels exposed to bisphenol A, diallyl phthalate and tetrabromodiphenyl ether-47. | Aquatic toxicology (Amsterdam, Netherlands) 20060601 |
The BEEP Stavanger Workshop: Mesocosm exposures. | Aquatic toxicology (Amsterdam, Netherlands) 20060601 |
Chronic toxicity of 2,4,2',4'-tetrabromodiphenyl ether on the marine alga Skeletonema costatum and the crustacean Daphnia magna. | Environmental toxicology and chemistry 20060601 |
Gene expression patterns in rainbow trout, Oncorhynchus mykiss, exposed to a suite of model toxicants. | Aquatic toxicology (Amsterdam, Netherlands) 20060525 |
Determination of HBCD, PBDEs and MeO-BDEs in California sea lions (Zalophus californianus) stranded between 1993 and 2003. | Marine pollution bulletin 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Identification of hydroxylated metabolites in 2,2',4,4'-tetrabromodiphenyl ether exposed rats. | Chemosphere 20060401 |
Disposition of BDE 47 in developing mice. | Toxicological sciences : an official journal of the Society of Toxicology 20060401 |
Impact of repeated exposure on the toxicokinetics of BDE 47 in mice. | Toxicological sciences : an official journal of the Society of Toxicology 20060201 |
Oral exposure of PBDE-47 in fish: toxicokinetics and reproductive effects in Japanese Medaka (Oryzias latipes) and fathead minnows (Pimephales promelas). | Environmental science & technology 20060115 |
Tissue localisation of tetra- and pentabromodiphenyl ether congeners (BDE-47, -85 and -99) in perinatal and adult C57BL mice. | Chemosphere 20060101 |
Metabolism and disposition of 2,2',4,4'- tetrabromodiphenyl ether following administration of single or multiple doses to rats and mice. | Xenobiotica; the fate of foreign compounds in biological systems 20060101 |
Absorption of [14C]-tetrabromodiphenyl ether (TeBDE) through human and rat skin in vitro. | Drug and chemical toxicology 20060101 |
Concentrations of polybrominated diphenyl ethers, polychlonnated biphenyls, and polychlorobiphenylols in serum from pregnant Faroese women and their children 7 years later. | Environmental science & technology 20051215 |
Inhibition and induction of aromatase (CYP19) activity by brominated flame retardants in H295R human adrenocortical carcinoma cells. | Toxicological sciences : an official journal of the Society of Toxicology 20051201 |
Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships. | Toxicological sciences : an official journal of the Society of Toxicology 20051101 |
Differential expression of CYP1A, 2B, and 3A genes in the F344 rat following exposure to a polybrominated diphenyl ether mixture or individual components. | Toxicological sciences : an official journal of the Society of Toxicology 20051101 |
In vitro estrogenicity of polybrominated flame retardants. | Aquatic toxicology (Amsterdam, Netherlands) 20050910 |
Brominated-chlorinated diphenyl ethers formed by thermolysis of polybrominated diphenyl ethers at low temperatures. | Chemosphere 20050901 |
In vivo and in vitro anti-androgenic effects of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture. | Toxicology and applied pharmacology 20050822 |
Toxicokinetics of BDE 47 in female mice: effect of dose, route of exposure, and time. | Toxicological sciences : an official journal of the Society of Toxicology 20050201 |
Menstrual function among women exposed to polybrominated biphenyls: a follow-up prevalence study. | Environmental health : a global access science source 20050101 |
Accumulation of PBDE-47 in primary cultures of rat neocortical cells. | Toxicological sciences : an official journal of the Society of Toxicology 20041101 |
Debromination of polybrominated diphenyl ether congeners BDE 99 and BDE 183 in the intestinal tract of the common carp (Cyprinus carpio). | Environmental science & technology 20040215 |
Optimization of solid-phase microextraction for the gas chromatography/mass spectrometry analysis of persistent organic pollutants. | Journal of AOAC International 20040101 |
Brominated flame retardants and phenolic endocrine disrupters in Finnish human adipose tissue. | Chemosphere 20031201 |
A review on human exposure to brominated flame retardants--particularly polybrominated diphenyl ethers. | Environment international 20030901 |
Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds. | Environment international 20030901 |
Comparing polybrominated diphenyl ether and polychlorinated biphenyl bioaccumulation in a food web in Grand Traverse Bay, Lake Michigan. | Archives of environmental contamination and toxicology 20030801 |
High body burdens of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) in California women. | Environmental health perspectives 20030701 |
Polybrominated dibenzo-p-dioxins, dibenzofurans, and diphenyl ethers in Japanese human adipose tissue. | Environmental science & technology 20030301 |
Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats-testing interactions and mechanisms for thyroid hormone effects. | Toxicology 20020815 |
Brominated flame retardants in archived serum samples from Norway: a study on temporal trends and the role of age. | Environmental science & technology 20020401 |
Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption. | Toxicological sciences : an official journal of the Society of Toxicology 20020301 |
Spatial distribution of polybrominated diphenyl ethers and polybrominated biphenyls in lake trout from the Laurentian Great Lakes. | Chemosphere 20020201 |
Brominated flame retardants in serum from U.S. blood donors. | Environmental science & technology 20011001 |
Brominated flame retardants: a novel class of developmental neurotoxicants in our environment? | Environmental health perspectives 20010901 |
Brominated flame retardants in plasma samples from three different occupational groups in Norway. | Journal of environmental monitoring : JEM 20010801 |
Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice. | Archives of toxicology 20010601 |
Plasma levels of persistent organohalogens and hormone levels in adult male humans. | Archives of environmental health 20010101 |