2-[4-(2H-1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine
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Clinical trials of dementia with Lewy bodies and Parkinson's disease dementia. | Current neurology and neuroscience reports 20121001 |
Myometry revealed medication-induced decrease in resting skeletal muscle stiffness in Parkinson's disease patients. | Clinical biomechanics (Bristol, Avon) 20120701 |
Opposing effects on the phrenic motor pathway attributed to dopamine-D1 and -D3/D2 receptor activation. | Respiratory physiology & neurobiology 20120430 |
Dose-dependent impulse control disorders in piribedil overdose. | Clinical neuropharmacology 20120101 |
Dyskinesias and treatment with pramipexole in patients with Parkinson's disease. | Parkinson's disease 20120101 |
Effects of stimulation and blockade of d(2) receptor on depression-like behavior in ovariectomized female rats. | ISRN pharmacology 20120101 |
Clinical aspects and management of levodopa-induced dyskinesia. | Parkinson's disease 20120101 |
Prescribed drugs and violence: a case/noncase study in the French PharmacoVigilance Database. | European journal of clinical pharmacology 20111101 |
The Movement Disorder Society Evidence-Based Medicine Review Update: Treatments for the motor symptoms of Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20111001 |
Initiation of treatment in early PD (evidences based). | Annals of Indian Academy of Neurology 20110701 |
Medical management of Parkinson's disease: focus on neuroprotection. | Current neuropharmacology 20110601 |
Enhanced glutamate, IP3 and cAMP activity in the cerebral cortex of unilateral 6-hydroxydopamine induced Parkinson's rats: effect of 5-HT, GABA and bone marrow cell supplementation. | Journal of biomedical science 20110101 |
Piribedil-induced sleep attacks in patients without Parkinson disease: a case series. | Clinical neuropharmacology 20110101 |
Agonist-specific voltage sensitivity at the dopamine D2S receptor--molecular determinants and relevance to therapeutic ligands. | Neuropharmacology 20110101 |
Case control polysomnographic studies of sleep disorders in Parkinson's disease. | PloS one 20110101 |
Pre-treatment with dopamine agonists influence L-dopa mediated rotations without affecting abnormal involuntary movements in the 6-OHDA lesioned rat. | Behavioural brain research 20101112 |
From the cell to the clinic: a comparative review of the partial D₂/D₃receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease. | Pharmacology & therapeutics 20101101 |
Delusional infestation induced by piribedil add-on in Parkinson's disease. | Pharmacopsychiatry 20100801 |
Orodispersible sublingual piribedil to abort OFF episodes: a single dose placebo-controlled, randomized, double-blind, cross-over study. | Movement disorders : official journal of the Movement Disorder Society 20100215 |
Is there an inhibitory-response-control system in the rat? Evidence from anatomical and pharmacological studies of behavioral inhibition. | Neuroscience and biobehavioral reviews 20100101 |
Impulse control disorder and piribedil: report of 5 cases. | Clinical neuropharmacology 20100101 |
Plasma neuropeptide Y: a biomarker for symptom severity in chronic fatigue syndrome. | Behavioral and brain functions : BBF 20100101 |
Cognitive psychiatry in India. | Indian journal of psychiatry 20100101 |
Parkinson's disease sleep scale, sleep logs, and actigraphy in the evaluation of sleep in parkinsonian patients. | Journal of neurology 20090901 |
Tinnitus treatment with piribedil guided by electrocochleography and acoustic otoemissions. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20090801 |
Ruthenium-catalyzed N-alkylation of amines and sulfonamides using borrowing hydrogen methodology. | Journal of the American Chemical Society 20090211 |
Dopamine Agonists and their risk to induce psychotic episodes in Parkinson's disease: a case-control study. | BMC neurology 20090101 |
Hallucinations: Etiology and clinical implications. | Industrial psychiatry journal 20090101 |
Mild cognitive impairment: The dilemma. | Indian journal of psychiatry 20090101 |
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans. | Current neuropharmacology 20080901 |
Current management of the cognitive dysfunction in Parkinson's disease: how far have we come? | Experimental biology and medicine (Maywood, N.J.) 20080801 |
Comparative effects of the dopaminergic agonists piribedil and bromocriptine in three different memory paradigms in rodents. | Journal of psychopharmacology (Oxford, England) 20080701 |
Blockage of dopaminergic D(2) receptors produces decrease of REM but not of slow wave sleep in rats after REM sleep deprivation. | Behavioural brain research 20080409 |
Impact of newer pharmacological treatments on quality of life in patients with Parkinson's disease. | CNS drugs 20080101 |
[Implication of piribedil (pronoran) in the treatment of Parkinson's disease; a clinical and pharmacoeconomic analysis]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101 |
Peripheral edema and dopamine agonists in Parkinson disease. | Archives of neurology 20071001 |
Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives. | International journal of nanomedicine 20070901 |
Identification of amino acid determinants of dopamine 2 receptor synthetic agonist function. | The Journal of pharmacology and experimental therapeutics 20070401 |
Genetic Contribution of Catechol-O-methyltransferase Polymorphism in Patients with Migraine without Aura. | Journal of clinical neurology (Seoul, Korea) 20070301 |
Impaired cognition and attention in adults: pharmacological management strategies. | Neuropsychiatric disease and treatment 20070201 |
Effects of the dopamine agonist piribedil on prefrontal temporal cortical network function in normal aging as assessed by verbal fluency. | Progress in neuro-psychopharmacology & biological psychiatry 20070130 |
About the anti-Parkinson equivalency of levodopa and dopamine agonists. | Clinical neuropharmacology 20070101 |
[Cognitive disturbances and dysfunction of neuromediator systems in cerebral vascular insufficiency after treatment with pronoran]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101 |
Early piribedil monotherapy of Parkinson's disease: A planned seven-month report of the REGAIN study. | Movement disorders : official journal of the Movement Disorder Society 20061201 |
The dopamine agonist piribedil with L-DOPA improves attentional dysfunction: relevance for Parkinson's disease. | The Journal of pharmacology and experimental therapeutics 20061101 |
Antidepressant-like properties of the anti-Parkinson agent, piribedil, in rodents: mediation by dopamine D2 receptors. | Behavioural pharmacology 20061101 |
Activation of D2-like receptors induces sympathetic climactic-like responses in male and female anaesthetised rats. | British journal of pharmacology 20060601 |
Restless legs syndrome: diagnosis and review of management options. | Neuropsychiatric disease and treatment 20060601 |
The Parkinson-Control study: a 1-year randomized, double-blind trial comparing piribedil (150 mg/day) with bromocriptine (25 mg/day) in early combination with levodopa in Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20060401 |
Enhancement in dissolution pattern of piribedil by molecular encapsulation with beta-cyclodextrin. | Methods and findings in experimental and clinical pharmacology 20060301 |
Pharmacokinetic optimisation in the treatment of Parkinson's disease : an update. | Clinical pharmacokinetics 20060101 |
Proposed dose equivalence for rapid switch between dopamine receptor agonists in Parkinson's disease: a review of the literature. | Clinical therapeutics 20060101 |
[The role of pronoran in the therapy of late stage of Parkinson's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101 |
Switching from levodopa to the long-acting dopamine D2/D3 agonist piribedil reduces the expression of dyskinesia while maintaining effective motor activity in MPTP-treated primates. | Clinical neuropharmacology 20060101 |
Prevalence and costs of parkinsonian syndromes associated with orthostatic hypotension. | Therapie 20060101 |
[Dopaminergic and noradrenergic therapy of cognitive impairment]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101 |
Pathophysiology and management of syncope in Kearns-Sayre syndrome. | The American heart hospital journal 20060101 |
[Effect of dopamine deficiency on the preparation of visually guided saccadic eye movements]. | Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20060101 |
A reversed-phase high-performance liquid chromatographic method for the determination of zafirlukast in pharmaceutical formulations and human plasma. | Journal of AOAC International 20060101 |
Chemically modified carbon paste electrode for the potentiometric flow injection analysis of piribedil in pharmaceutical preparation and urine. | Journal of pharmaceutical and biomedical analysis 20050715 |
End-of-dose akinesia after a single intravenous infusion of the dopaminergic agonist piribedil in Parkinson's disease patients: a pharmacokinetic/pharmacodynamic, randomized, double-blind study. | Movement disorders : official journal of the Movement Disorder Society 20050701 |
Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004. | Movement disorders : official journal of the Movement Disorder Society 20050501 |
The effects of dopaminergic agonists on genital reflexes in paradoxical sleep-deprived male rats. | Physiology & behavior 20050215 |
[Efficacy of pronoran in age-related memory impairment]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101 |
[An impact of pronoran on cognitive and affective disorders in Parkinson's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101 |
[Modern aproaches to the treatment of early stages of Parkinson disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101 |
Cognitive skill learning in healthy older adults after 2 months of double-blind treatment with piribedil. | Psychopharmacology 20041101 |
Efficacy and safety of piribedil in early combination with L-dopa in the treatment of Parkinson's disease: a 6-month open study. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20041101 |
Drug treatment of Parkinson's disease. | Dialogues in clinical neuroscience 20040901 |
Drugs in development for Parkinson's disease. | Current opinion in investigational drugs (London, England : 2000) 20040701 |
Determination of piribedil in pharmaceutical formulations by micellar electrokinetic capillary chromatography. | Analytical and bioanalytical chemistry 20040501 |
[The effectiveness and tolerance of piribedil as adjunct therapy to levodopa in patients with Parkinson's disease: a nine month follow up]. | Revista de neurologia 20040401 |
Adsorptive stripping voltammetric behaviour of azomethine group in pyrimidine-containing drugs. | Journal of pharmaceutical and biomedical analysis 20040218 |
[Clinical and stabilometric analysis of postural instability in Parkinson's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101 |
[Treatment of Parkinson's disease: use of piribedil]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101 |
Acute treatment of migraine. Breaking the paradigm of monotherapy. | BMC neurology 20040101 |
[Pronoran in the treatment of mental organic syndrome in the elderly]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101 |
Piribedil as an adjunct to levodopa in advanced Parkinson's disease: the Asian experience. | Parkinsonism & related disorders 20031201 |
Quantitative determination of some pharmaceutical piperazine derivatives through complexation with iron(III) chloride. | Farmaco (Societa chimica italiana : 1989) 20030801 |
Treatment of memory impairment, vertigo and tinnitus in the elderly with piribedil in an Indian general practice setting. | Journal of the Indian Medical Association 20030801 |
Piribedil enhances frontocortical and hippocampal release of acetylcholine in freely moving rats by blockade of alpha 2A-adrenoceptors: a dialysis comparison to talipexole and quinelorane in the absence of acetylcholinesterase inhibitors. | The Journal of pharmacology and experimental therapeutics 20030401 |
Efficacy of piribedil as early combination to levodopa in patients with stable Parkinson's disease: a 6-month, randomized, placebo-controlled study. | Movement disorders : official journal of the Movement Disorder Society 20030401 |
Electroanalytical characteristics of piribedil and its differential pulse and square wave voltammetric determination in pharmaceuticals and human serum. | Journal of pharmaceutical and biomedical analysis 20030310 |
Piribedil and bromocriptine in Parkinson's disease: a single-blind crossover study. | Acta neurologica Scandinavica 20030301 |
Age-related mild cognitive deficit: a ready-to-use concept? | Dialogues in clinical neuroscience 20030301 |
Piribedil-induced sleep attacks in Parkinson's disease. | Fundamental & clinical pharmacology 20030201 |
[The use of pronoran (piribedil) in Parkinson's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101 |
[Use of pronoran (piribedil) in Parkinson's disease: the results of a multicenter study]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101 |
Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes. | The Journal of pharmacology and experimental therapeutics 20021101 |
Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor. | The Journal of pharmacology and experimental therapeutics 20021101 |
Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. III. Agonist and antagonist properties at serotonin, 5-HT(1) and 5-HT(2), receptor subtypes. | The Journal of pharmacology and experimental therapeutics 20021101 |
Repeated administration of piribedil induces less dyskinesia than L-dopa in MPTP-treated common marmosets: a behavioural and biochemical investigation. | Movement disorders : official journal of the Movement Disorder Society 20020901 |
[Alpha-2 adrenergic receptors and Parkinson's disease]. | Presse medicale (Paris, France : 1983) 20020727 |
Sleep attacks in patients taking dopamine agonists: review. | BMJ (Clinical research ed.) 20020622 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Psychomotor and cognitive effects of piribedil, a dopamine agonist, in young healthy volunteers. | Fundamental & clinical pharmacology 20020201 |
Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease. | Clinical pharmacokinetics 20020101 |
Choosing the right dopamine agonist for patients with Parkinson's disease. | Current medical research and opinion 20020101 |
DA agonists -- non-ergot derivatives: piribedil: management of Parkinson's disease. | Movement disorders : official journal of the Movement Disorder Society 20020101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020101 |
[Use of dopamine agonists in the treatment of Parkinson's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101 |
[Use of dopamine analogs in Parkinson's disease treatment]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101 |
Randomized study of the dopamine receptor agonist piribedil in the treatment of mild cognitive impairment. | The American journal of psychiatry 20010901 |
Antiparkinsonian agent piribedil displays antagonist properties at native, rat, and cloned, human alpha(2)-adrenoceptors: cellular and functional characterization. | The Journal of pharmacology and experimental therapeutics 20010601 |
Piribedil for restless legs syndrome: a pilot study. | Movement disorders : official journal of the Movement Disorder Society 20010501 |
[Parkinson disease: diagnostic and therapeutic criteria]. | Presse medicale (Paris, France : 1983) 20010303 |
Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey. | Brain : a journal of neurology 20010301 |
Formulation and in vitro-in vivo evaluation of piribedil solid lipid micro- and nanoparticles. | Journal of microencapsulation 20010101 |
Pharmacological treatment for aphasia following stroke. | The Cochrane database of systematic reviews 20010101 |
Sleep attacks and Parkinson's disease treatment. | Lancet (London, England) 20000415 |
Discriminative stimulus properties of the dopamine D3 receptor agonists, PD128,907 and 7-OH-DPAT: a comparative characterization with novel ligands at D3 versus D2 receptors. | Neuropharmacology 20000214 |
[Electrophysiological and pharmacological analysis of L-dopa-induced dyskinesia and tardive dyskinesia (author's transl)]. | Journal de physiologie 19810401 |
Parkinsonism by haloperidol and piribedil. | Psychopharmacology 19781031 |
Dopamine receptor stimulation in the treatment of depression: piribedil (ET-495). | Neuropsychobiology 19780101 |
A comparison of piribedil, procyclidine and placebo in the control of phenothiazine-induced parkinsonism. | The British journal of psychiatry : the journal of mental science 19770601 |
Piribedil: its synergistic effect in multidrug regimens for parkinsonism. | Neurology 19760501 |
Clinical and pharmacological evaluation of the effects of piribedil in patients with parkinsonism. | Acta neurologica Scandinavica 19750101 |