Home Other Building Blocks 1-9-Luteinizing hormone-releasing factor (swine), 6-D-leucine-9-(N-ethyl-L-prolinamide)-, acetate (1:1)

1-9-Luteinizing hormone-releasing factor (swine), 6-D-leucine-9-(N-ethyl-L-prolinamide)-, acetate (1:1)

CAS No.:
74381-53-6
Catalog Number:
AG0039VT
Molecular Formula:
C61H86N16O13
Molecular Weight:
1251.4349
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$91
- +
5mg
≥98%
1 week
United States
$161
- +
10mg
99%
1 week
United States
$207
- +
50mg
99%
1 week
United States
$357
- +
100mg
99%
1 week
United States
$523
- +
Product Description
Catalog Number:
AG0039VT
Chemical Name:
1-9-Luteinizing hormone-releasing factor (swine), 6-D-leucine-9-(N-ethyl-L-prolinamide)-, acetate (1:1)
CAS Number:
74381-53-6
Molecular Formula:
C61H86N16O13
Molecular Weight:
1251.4349
MDL Number:
MFCD00072080
IUPAC Name:
acetic acid;(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
InChI:
InChI=1S/C59H84N16O12.C2H4O2/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40;1-2(3)4/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64);1H3,(H,3,4)/t40-,41-,42-,43+,44-,45-,46-,47-,48-;/m0./s1
InChI Key:
RGLRXNKKBLIBQS-XNHQSDQCSA-N
SMILES:
CCNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)N1)Cc1[nH]cnc1)COC(=O)C)Cc1ccc(cc1)O)CC(C)C)CC(C)C)CCCNC(=N)N
UNII:
37JNS02E7V
Properties
Complexity:
2420  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
9  
Defined Bond Stereocenter Count:
0
Exact Mass:
1268.667g/mol
Formal Charge:
0
Heavy Atom Count:
91  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
16  
Isotope Atom Count:
0
Molecular Weight:
1269.473g/mol
Monoisotopic Mass:
1268.667g/mol
Rotatable Bond Count:
32  
Topological Polar Surface Area:
469A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
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Structural elucidation of Leuprolide and its analogues in solution: insight into their bioactive conformation. Amino acids 20101101
Randomized, comparative pilot study of pituitary suppression with depot leuprorelin versus cetrorelix acetate 3 mg in gonadotropin stimulation protocols for oocyte donors. Fertility and sterility 20101101
Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women. The Journal of clinical endocrinology and metabolism 20101101
Testosterone may increase selective attention to threat in young male macaques. Hormones and behavior 20101101
Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma. Human reproduction (Oxford, England) 20101101
LH (as HCG) and FSH surges for final oocyte maturation: sometimes it takes two to tango? Reproductive biomedicine online 20101101
[Molecular-targeted therapy for spinal and bulbar muscular atrophy (SBMA)]. Rinsho shinkeigaku = Clinical neurology 20101101
Gonadotropin releasing hormone antagonists suppress aromatase and anti-Müllerian hormone expression in human granulosa cells. Fertility and sterility 20101001
Testosterone suppresses hepcidin in men: a potential mechanism for testosterone-induced erythrocytosis. The Journal of clinical endocrinology and metabolism 20101001
Reversal of age-related thymic involution by an LHRH agonist in miniature swine. Transplant immunology 20101001
Leuprolide stimulation testing for the evaluation of early female sexual maturation. Clinical endocrinology 20100901
GnRH receptor and peritoneal plasmin activity. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100901
Hypersensitivity vasculitis associated with leuprolide (Lupron). Cutaneous and ocular toxicology 20100901
Efficacy and safety of leuprorelin in patients with spinal and bulbar muscular atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial. The Lancet. Neurology 20100901
Sterile abscess formation in response to two separate branded long-acting gonadotropin-releasing hormone agonists. Clinical therapeutics 20100901
Gonadotropin-releasing hormone agonist to induce final oocyte maturation prevents the development of ovarian hyperstimulation syndrome in high-risk patients and leads to improved clinical outcomes compared with coasting. Fertility and sterility 20100801
Changes in alkaline phosphatase levels in patients with prostate cancer receiving degarelix or leuprolide: results from a 12-month, comparative, phase III study. BJU international 20100701
Adenomyosis has no adverse effects on IVF/ICSI outcomes in women with endometriosis treated with long-term pituitary down-regulation before IVF/ICSI. European journal of obstetrics, gynecology, and reproductive biology 20100701
Androgen blockade for the treatment of high-flow priapism. The journal of sexual medicine 20100701
GnRH agonist administration in the luteal phase of IVF cycles: still an experimental approach. Reproductive biomedicine online 20100701
Duration of first off-treatment interval is prognostic for time to castration resistance and death in men with biochemical relapse of prostate cancer treated on a prospective trial of intermittent androgen deprivation. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100601
Additional analysis of the secondary end point of biochemical recurrence rate in a phase 3 trial (CS21) comparing degarelix 80 mg versus leuprolide in prostate cancer patients segmented by baseline characteristics. European urology 20100501
Randomized GH trial with two different dosages in combination with a GnRH analogue in short small for gestational age children: effects on metabolic profile and serum GH, IGF1, and IGFBP3 levels. European journal of endocrinology 20100501
Do GnRH analogues directly affect human endometrial epithelial cell gene expression? Molecular human reproduction 20100501
Microdose flare versus antagonist for poor responders. Fertility and sterility 20100501
Comparative analysis of six months formulation of LHRH analogues for prostate cancer treatment. Archivos espanoles de urologia 20100501
Total androgen blockade versus a luteinizing hormone-releasing hormone agonist alone in men with high-risk prostate cancer treated with radiotherapy. International journal of radiation oncology, biology, physics 20100401
Leuprolide acetate gonadotrophin response patterns during female puberty. Clinical endocrinology 20100401
FSH aggravates periodontitis-related bone loss in ovariectomized rats. Journal of dental research 20100401
Protective effects of follicle-stimulating hormone inhibitor on alveolar bone loss resulting from experimental periapical lesions in ovariectomized rats. Journal of endodontics 20100401
Effectiveness, pharmacokinetics, and safety of a new sustained-release leuprolide acetate 3.75-mg depot formulation for testosterone suppression in patients with prostate cancer: a Phase III, open-label, international multicenter study. Clinical therapeutics 20100401
The mechanism responsible for the supraphysiologic gonadotropin surge in females treated with gonadotropin-releasing hormone (GnRH) agonist and primed with GnRH antagonist. Fertility and sterility 20100315
Prevention of paclitaxel and cisplatin induced ovarian damage in rats by a gonadotropin-releasing hormone agonist. Fertility and sterility 20100315
Fertility preservation during treatment is a growing issue for women. Journal of the National Cancer Institute 20100303
Subjective and objective measures of late genitourinary morbidity following hypofractionated radiotherapy in men with prostate cancer. Prostate cancer and prostatic diseases 20100301
Comparison of follicular fluid and serum cytokine concentrations in women undergoing assisted reproductive treatment with GnRH agonist long and antagonist protocols. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100301
Immunosuppressive CD14+HLA-DRlow/- monocytes in prostate cancer. The Prostate 20100301
Changes in tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma after GnRH agonist therapy. Human reproduction (Oxford, England) 20100301
Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial. Human reproduction (Oxford, England) 20100301
Add-back therapy use and its impact on LA persistence in patients with endometriosis. Current medical research and opinion 20100301
Ovarian stimulation in women with high and low body mass index: GnRH agonist versus GnRH antagonist. Reproductive biomedicine online 20100301
Effect of vascular endothelial growth factor and interleukin-1beta on apoptosis in endometrial cell cultures from patients with endometriosis and controls. Journal of reproductive immunology 20100301
Gonadotropin-releasing hormone agonist or human chorionic gonadotropin for final oocyte maturation in an oocyte donor program. Fertility and sterility 20100201
Outcome of intracytoplasmic sperm injection with and without polar body diagnosis of oocytes. Fertility and sterility 20100201
A randomized controlled trial of add-back estrogen or placebo on cognition in men with prostate cancer receiving an antiandrogen and a gonadotropin-releasing hormone analog. Psychoneuroendocrinology 20100201
Coexistence of catamenial pneumothorax and catamenial hemoptysis in a patient with pulmonary hemangiomatosis-like foci: a case report. The Journal of thoracic and cardiovascular surgery 20100201
LH supplementation in down-regulated women undergoing assisted reproduction with baseline low serum LH levels. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20100201
Profound teratospermia does not influence sex chromosomal aneuploidy rate in in vitro fertilization-preimplantation genetic diagnosis cycles. Fertility and sterility 20100201
Down-regulation of serum gonadotropins is as effective as estrogen replacement at improving menopause-associated cognitive deficits. Journal of neurochemistry 20100201
Effects of the levonorgestrel-releasing intrauterine system on cardiovascular risk markers in patients with endometriosis: a comparative study with the GnRH analogue. Contraception 20100201
Cycles triggered with GnRH agonist: exploring low-dose HCG for luteal support. Reproductive biomedicine online 20100201
Metastatic prostatic adenocarcinoma mimicking inflammatory breast carcinoma: a case report. Clinical breast cancer 20100201
Acute toxicity in high-risk prostate cancer patients treated with androgen suppression and hypofractionated intensity-modulated radiotherapy. International journal of radiation oncology, biology, physics 20100101
Apoplexy in non functioning pituitary adenoma after one dose of leuprolide as treatment for prostate cancer. Pituitary 20100101
Cognition is not modified by large but temporary changes in sex hormones in men. The Journal of clinical endocrinology and metabolism 20100101
Higher leuprolide dose does not diminish the ovarian response to gonadotropins in a protocol using pre-treatment with oral contraceptives. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20100101
Effectiveness of the combined recombinant human growth hormone and gonadotropin-releasing hormone analog therapy in pubertal patients with short stature due to SHOX deficiency. The Journal of clinical endocrinology and metabolism 20100101
Morphologic patterns of human endometrial epithelium in women with uterine myomata treated with leuprorelin acetate. Gynecologic and obstetric investigation 20100101
GnRH agonist therapy to protect ovarian function in young Korean breast cancer patients. Journal of Korean medical science 20100101
Final report on low-dose estramustine phosphate (EMP) monotherapy and very low-dose EMP therapy combined with LH-RH agonist for previously untreated advanced prostate cancer. Aktuelle Urologie 20100101
[Neuroendocrine differentiation in adenocarcinoma of the prostate during hormonal treatment : a case report]. Hinyokika kiyo. Acta urologica Japonica 20100101
Effects of prolonging administration gonadotropin on unexpectedly poor ovarian responders undergoing in vitro fertilization. Reproductive biology and endocrinology : RB&E 20100101
Endometriosis with massive hemorrhagic ascites. Indian journal of cancer 20100101
Bilateral testicular metastasis from prostatic adenocarcinoma mimicking an intertubular pattern of seminoma and expressing Rhamm. Journal of cancer research and therapeutics 20100101
Effect of ritanserin and leuprolide alone and combined on marble-burying behavior of mice. Acta poloniae pharmaceutica 20100101
Effects of luteinizing hormone-releasing hormone and arginine-vasotocin on the sperm-release response of Günther's Toadlet, Pseudophryne guentheri. Reproductive biology and endocrinology : RB&E 20100101
A comparison of pregnancy rates following fresh and frozen embryo transfer according to the use of leuprolide acetate vs ganirelix vs cetrorelix. Clinical and experimental obstetrics & gynecology 20100101
Hormonal induction of gamete release, and in-vitro fertilisation, in the critically endangered southern corroboree frog, Pseudophryne corroboree. Reproductive biology and endocrinology : RB&E 20100101
Effects of testosterone on cognition in young adult male rhesus monkeys. Physiology & behavior 20091207
A morphological study of granulomas induced by subcutaneous injection of leuprorelin acetate. Journal of cutaneous pathology 20091201
Effects of variations in serum estradiol concentrations on secretory endometrial development and function in experimentally induced cycles in normal women. Fertility and sterility 20091201
Brain and cognition. Is there any case for improving cognitive function in menopausal women using estrogen treatment? Minerva ginecologica 20091201
Degarelix 240/80 mg: a new treatment option for patients with advanced prostate cancer. Expert review of anticancer therapy 20091201
Systemic allergic dermatitis caused by the solvent of Eligard. Contact dermatitis 20091201
Effects of leuprolide acetate on selected blood and fecal sex hormones in Hispaniolan Amazon parrots (Amazona ventrais). Journal of avian medicine and surgery 20091201
Disseminated intravascular coagulation secondary to metastatic prostate cancer: case report and review of the literature. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20091201
Comparison of three doses of leuprolide acetate in the treatment of central precocious puberty: preliminary results. Clinical endocrinology 20091101
A novel androgen-dependent prostate cancer xenograft model derived from skin metastasis of a Japanese patient. The Prostate 20091101
Recurrence rate of endometrioma after laparoscopic cystectomy: a comparative randomized trial between post-operative hormonal suppression treatment or dietary therapy vs. placebo. European journal of obstetrics, gynecology, and reproductive biology 20091101
N-terminal propeptide of type III procollagen as a biomarker of anabolic response to recombinant human GH and testosterone. The Journal of clinical endocrinology and metabolism 20091101
[Molecular-targeted therapy for neurodegenerative diseases]. Rinsho shinkeigaku = Clinical neurology 20091101
[Molecular-targeted therapies for spinal and bulbar muscular atrophy]. Rinsho shinkeigaku = Clinical neurology 20091101
Rapid and sensitive liquid chromatography-tandem mass spectrometry method for the determination of leuprolide in human serum. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001
Comparison of surgery alone and combined surgical-medical treatment in the management of symptomatic uterine adenomyoma. Fertility and sterility 20090901
Short term results from GHRH analogue use in pre-menopausal breast cancer in Korea. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20090901
Long-term effects of intermittent androgen suppression on testosterone recovery and bone mineral density: results of a 33-month observational study. BJU international 20090901
Radiation dose predicts for biochemical control in intermediate-risk prostate cancer patients treated with low-dose-rate brachytherapy. International journal of radiation oncology, biology, physics 20090901
Follicular development, acquisition of mature oocytes, and pregnancy after 2 weeks of leuprolide acetate administration during the midluteal phase. Fertility and sterility 20090901
[Legal reference standards for prescription qualified drugs for withholding Leuporelin production]. Der Urologe. Ausg. A 20090901
Characterization of the intra-prostatic immune cell infiltration in androgen-deprived prostate cancer patients. Journal of immunological methods 20090831
Case records of the Massachusetts General Hospital. Case 25-2009. A 36-year-old woman with hormone-receptor-positive breast cancer. The New England journal of medicine 20090813
Evaluation of different add-back estradiol and progesterone treatments to gonadotropin-releasing hormone agonist treatment in patients with premenstrual dysphoric disorder. American journal of obstetrics and gynecology 20090801
GnRH receptor expression in human prostate cancer cells is affected by hormones and growth factors. Endocrine 20090801
Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. European journal of endocrinology 20090801
Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women. American journal of physiology. Endocrinology and metabolism 20090801
Regulation of basal, pulsatile, and entropic (patterned) modes of GH secretion in a putatively low-somatostatin milieu in women. American journal of physiology. Endocrinology and metabolism 20090801
The effect of combined surgical-medical intervention on the progression of endometriosis in an adolescent and young adult population. Journal of pediatric and adolescent gynecology 20090801
[Molecular-targeted therapy for motor neuron disease]. Brain and nerve = Shinkei kenkyu no shinpo 20090801
Factors other than sex steroids modulate GHRH and GHRP-2 efficacies in men: evaluation using a GnRH agonist/testosterone clamp. The Journal of clinical endocrinology and metabolism 20090701
Adjuncts for ovarian stimulation: when do we adopt 'orphan indications' for approved drugs? Fertility and sterility 20090701
Importance of leuprolide acetate variable dosing for precocious puberty: a range of acceptable suppression. Journal of pediatric endocrinology & metabolism : JPEM 20090701
Microdose gonadotropin-releasing hormone agonist flare-up protocol versus multiple dose gonadotropin-releasing hormone antagonist protocol in poor responders undergoing intracytoplasmic sperm injection-embryo transfer cycle. Fertility and sterility 20090601
Relationship between hot flashes and distress in men receiving androgen deprivation therapy for prostate cancer. Psycho-oncology 20090601
A possible participation of gonadotropin-releasing hormone in the neuroleptic and cataleptic effect of haloperidol. Neuropeptides 20090601
GnRH agonist therapy in a patient with recurrent ovarian granulosa cell tumors. Journal of Korean medical science 20090601
Use of a gonadotropin-releasing hormone agonist to manage perimenopausal women with symptomatic uterine myomas. Taiwanese journal of obstetrics & gynecology 20090601
Gonadotropin-releasing hormone agonist pretreatment did not decrease postoperative adhesion formation after abdominal myomectomy in a randomized control trial. Fertility and sterility 20090501
Long-term effects of GnRH agonist, GnRH antagonist, and estrogen plus progesterone treatment on apoptosis related genes in rat ovary. Fertility and sterility 20090501
Initial growth deceleration during GnRH analogue therapy for precocious puberty. Clinical endocrinology 20090501
Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles. Colloids and surfaces. B, Biointerfaces 20090501
Determinants of GH-releasing hormone and GH-releasing peptide synergy in men. American journal of physiology. Endocrinology and metabolism 20090501
Luteinizing hormone-releasing hormone enhances T cell recovery following allogeneic bone marrow transplantation. Journal of immunology (Baltimore, Md. : 1950) 20090501
Iron deficiency in non-dialysis chronic kidney disease. Kidney international 20090401
Aromatase inhibitors prevent the estrogen rise associated with the flare effect of gonadotropins in patients treated with GnRH agonists. Fertility and sterility 20090401
Variations in blood ghrelin levels in prostate cancer patients submitted to hormone suppressive treatment. Anticancer research 20090401
Hot flashes during androgen deprivation therapy with luteinizing hormone-releasing hormone agonist combined with steroidal or nonsteroidal antiandrogen for prostate cancer. Urology 20090301
Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer. Anti-cancer drugs 20090301
Efficacy over time of LHRH analogs in the treatment of PCa--a prospective analysis using serum testosterone to determine dosing intervals. Urology 20090301
Reduced neuronal responsiveness to visual sexual stimuli in a pedophile treated with a long-acting LH-RH agonist. The journal of sexual medicine 20090301
A double-blind randomized crossover study of oral thalidomide versus placebo for androgen dependent prostate cancer treated with intermittent androgen ablation. The Journal of urology 20090301
Neuropathology and therapeutic intervention in spinal and bulbar muscular atrophy. International journal of molecular sciences 20090301
Pharmacologically induced hypogonadism and sexual function in healthy young women and men. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201
Anti-androgen treatment for spinal and bulbar muscular atrophy. Annals of neurology 20090201
Phase 2 trial of leuprorelin in patients with spinal and bulbar muscular atrophy. Annals of neurology 20090201
Overnight luteinizing and follicle stimulating hormone profiles during GnRHa treatment in short girls born small for gestational age. Journal of pediatric endocrinology & metabolism : JPEM 20090201
Addressing bone loss in the cancer survivor. Oncology (Williston Park, N.Y.) 20090201
Microdose follicular flare: a viable alternative for normal-responding patients undergoing in vitro fertilization? Fertility and sterility 20090101
The effect of selecting oocytes for insemination and transferring all resultant embryos without selection on outcomes of assisted reproduction. Fertility and sterility 20090101
Antral follicle count (AFC) can be used in the prediction of ovarian response but cannot predict the oocyte/embryo quality or the in vitro fertilization outcome in an egg donation program. Fertility and sterility 20090101
Postoperative long-term maintenance therapy with oral contraceptives after gonadotropin-releasing hormone analog treatment in women with ovarian endometrioma. Journal of minimally invasive gynecology 20090101
Neoadjuvant platelet derived growth factor receptor inhibitor therapy combined with docetaxel and androgen ablation for high risk localized prostate cancer. The Journal of urology 20090101
Safety and clinical efficacy of a new 6-month depot formulation of leuprorelin acetate in patients with prostate cancer in Europe. Prostate cancer and prostatic diseases 20090101
Twenty-five year evolution of medical hormonal therapy for prostate cancer. BJU international 20090101
Overnight levels of luteinizing hormone, follicle-stimulating hormone and growth hormone before and during gonadotropin-releasing hormone analogue treatment in short boys born small for gestational age. Hormone research 20090101
Utility of single luteinizing hormone determination 3 h after depot leuprolide in monitoring therapy of gonadotropin-dependent precocious puberty. Pituitary 20090101
Complete remission of OC-resistant catamenial shoulder joint pain and inguinal pain associated with extraperitoneal endometriosis following personalized GnRH agonist therapy. Clinical and experimental obstetrics & gynecology 20090101
Gonadotropin-releasing hormone agonist reduces aromatase cytochrome P450 and cyclooxygenase-2 in ovarian endometrioma and eutopic endometrium of patients with endometriosis. Gynecologic and obstetric investigation 20090101
Six-month depot formulation of leuprorelin acetate in the treatment of prostate cancer. Clinical interventions in aging 20090101
Growth outcome during GnRH agonist treatments for slowly progressive central precocious puberty. Neuroendocrinology 20090101
Successful long-term management of adenomyosis associated with deep thrombosis by low-dose gonadotropin-releasing hormone agonist therapy. Clinical and experimental obstetrics & gynecology 20090101
Leuprolide acetate reduces both in vivo and in vitro ovarian steroidogenesis in infertile women undergoing assisted reproduction. Steroids 20081222
Luteinized thecoma associated with sclerosing peritonitis--conservative surgical approach followed by corticosteroid and GnRH agonist treatment--a case report. Gynecologic oncology 20081201
Uterine ultrasonographic changes during endometriosis treatment: a comparison between levonorgestrel-releasing intrauterine devices and a gonadotropin-releasing hormone agonist. Ultrasound in medicine & biology 20081201
Anaemia following initiation of androgen deprivation therapy for metastatic prostate cancer: a retrospective chart review. The aging male : the official journal of the International Society for the Study of the Aging Male 20081201
Pharmacology of sexually compulsive behavior. The Psychiatric clinics of North America 20081201
Comparison of the effects of cetrorelix, a GnRH antagonist, and leuprolide, a GnRH agonist, on experimental endometriosis. The journal of obstetrics and gynaecology research 20081201
The efficacy and safety of degarelix: a 12-month, comparative, randomized, open-label, parallel-group phase III study in patients with prostate cancer. BJU international 20081201
Protective effect of leuprolide on ovarian function in young women treated with adjuvant chemotherapy for early breast cancer: a multicenter phase II study. Journal of chemotherapy (Florence, Italy) 20081201
How should we diagnose and monitor central precocious puberty? Journal of pediatric endocrinology & metabolism : JPEM 20081201
The diagnostic value of a brief GnRH analogue stimulation test in girls with central precocious puberty: a single 30-minute post-stimulation LH sample is adequate. Journal of pediatric endocrinology & metabolism : JPEM 20081201
[Predictive factors for height gain in idiopathic central precocious puberty treated with GnRH analogues]. Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 20081201
Watchful waiting beats androgen deprivation therapy in early prostate cancer. Journal of the National Cancer Institute 20081105
Comparison of multiple dose GnRH antagonist and minidose long agonist protocols in poor responders undergoing in vitro fertilization: a randomized controlled trial. Archives of gynecology and obstetrics 20081101
Changes in muscle mass, muscle strength, and power but not physical function are related to testosterone dose in healthy older men. Journal of the American Geriatrics Society 20081101
Evaluation of the American version of the 30-item Endometriosis Health Profile (EHP-30). Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20081101
Permeation characteristics of oligoarginine through intestinal epithelium and its usefulness for intestinal peptide drug delivery. Journal of controlled release : official journal of the Controlled Release Society 20081021
Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081020
In vivo evaluation and in vitro metabolism of leuprolide in mice--mass spectrometry-based biomarker measurement for efficacy and toxicity. Journal of mass spectrometry : JMS 20081001
Endometrial development and function in experimentally induced luteal phase deficiency. The Journal of clinical endocrinology and metabolism 20081001
Kinetics of serum androgen normalization and factors associated with testosterone reserve after limited androgen deprivation therapy for nonmetastatic prostate cancer. The Journal of urology 20081001
Estrogen, testosterone, and sequential movement in men. Behavioral neuroscience 20081001
Variations in L-selectin ligand expression in the luteal-phase endometrium after final oocyte maturation with human chorionic gonadotropin compared with a gonadotropin-releasing hormone agonist. Fertility and sterility 20080901
Undetectable level of prostate specific antigen (PSA) nadir predicts PSA biochemical failure in local prostate cancer with delayed-combined androgen blockade. Japanese journal of clinical oncology 20080901
Semiquantitative assessment of MR imaging in prediction of efficacy of gonadotropin-releasing hormone agonist for volume reduction of uterine leiomyoma: initial experience. Radiology 20080901
A randomised controlled trial comparing GnRH antagonist cetrorelix with GnRH agonist leuprorelin for endometrial thinning prior to transcervical resection of endometrium. BJOG : an international journal of obstetrics and gynaecology 20080901
Endometriosis can evade diagnosis. RN 20080901
Effect of medical castration on CYP3A4 enzyme activity using the erythromycin breath test. Cancer chemotherapy and pharmacology 20080801
Gonadotropin-releasing hormone agonist blocks anxiogenic-like and depressant-like effect of corticotrophin-releasing hormone in mice. Neuropeptides 20080801
ACOG practice bulletin. Alternatives to hysterectomy in the management of leiomyomas. Obstetrics and gynecology 20080801
Comparison of clinical efficacy between a single administration of long-acting gonadotrophin-releasing hormone agonist (GnRHa) and daily administrations of short-acting GnRHa in in vitro fertilization-embryo transfer cycles. Journal of Korean medical science 20080801
The pharmacokinetics and pharmacodynamics of a new sustained-release leuprolide acetate depot compared to market references. International journal of clinical pharmacology and therapeutics 20080801
Gonadotropin-releasing hormone agonist combined with a reduced dose of human chorionic gonadotropin for final oocyte maturation in fresh autologous cycles of in vitro fertilization. Fertility and sterility 20080701
Tibolone reverses the cognitive effects caused by leuprolide acetate administration, improving mood and quality of life in patients with symptomatic uterine leiomyomas. Fertility and sterility 20080701
Factors determining normal adult height in girls with gonadotropin-dependent precocious puberty treated with depot gonadotropin-releasing hormone analogs. The Journal of clinical endocrinology and metabolism 20080701
Subacute cutaneous lupus erythematosus in a leuprorelin-treated patient with prostate carcinoma. The British journal of dermatology 20080701
Sex hormone effects on body fluid regulation. Exercise and sport sciences reviews 20080701
Effects of central administration of gonadotropin-releasing hormone agonists and antagonist on elevated plus-maze and social interaction behavior in rats. Behavioural pharmacology 20080701
Rapid testosterone cycling and chemotherapy for prostate cancer: a way forward or return to the past? Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080620
Phase II trial of docetaxel with rapid androgen cycling for progressive noncastrate prostate cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080620
Risk of prostate cancer recurrence in men treated with radiation alone or in conjunction with combined or less than combined androgen suppression therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080620
Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation. Blood 20080615
Increased marble-burying behavior in ethanol-withdrawal state: modulation by gonadotropin-releasing hormone agonist. European journal of pharmacology 20080610
Leuprolide: a luteinizing hormone releasing hormone agonist attenuates ethanol withdrawal syndrome and ethanol-induced locomotor sensitization in mice. Neuropeptides 20080601
Reproductive hormones regulate the selective permeability of the blood-brain barrier. Biochimica et biophysica acta 20080601
Effect of ovarian suppression with gonadotropin-releasing hormone agonist on glucose disposal and insulin secretion. American journal of physiology. Endocrinology and metabolism 20080601
[Guide to the treatment and care of lymphangioleiomyomatosis]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20080601
Metabolic changes during gonadotropin-releasing hormone agonist therapy for prostate cancer: differences from the classic metabolic syndrome. Cancer 20080515
Metabolic syndrome and prostate cancer. Cancer 20080515
Goserelin versus leuprolide before hysterectomy for uterine fibroids. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20080501
Equivalent and sufficient effects of leuprolide acetate and goserelin acetate to suppress serum testosterone levels in patients with prostate cancer. BJU international 20080501
Combined hypofractionated radiation and hormone therapy for the treatment of intermediate-risk prostate cancer. International journal of radiation oncology, biology, physics 20080501
GnRH antagonists may affect endometrial receptivity. Fertility and sterility 20080501
Pathological evaluation of uterine leiomyomas treated with gonadotropin-releasing hormone agonist (GnRH-a) therapy: role of mast cells and a possible mechanism of GnRH-a resistance in leiomyomas. Pathology international 20080501
Tricuspid valve thrombus: a case report associated with gonadotropin-releasing hormone analogue therapy and review of the literature. The Canadian journal of cardiology 20080501
A potential means of investigating the role of luteinizing hormone in the pathogenesis of Alzheimer disease. Clinical medicine & research 20080501
Regulation of ovarian angiogenesis and apoptosis by GnRH-I analogs. Molecular reproduction and development 20080401
Gene-environment interactions, not neonatal growth hormone deficiency, time puberty in female rhesus monkeys. Biology of reproduction 20080401
Correlates between hyperinsulinism and hyperandrogenemia? Fertility and sterility 20080401
Prospective, randomized, comparative study of leuprorelin + human menopausal gonadotropins versus ganirelix + recombinant follicle-stimulating hormone in oocyte donors and pregnancy rates among the corresponding recipients. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080401
Complete response to the combination therapy with androgen blockade and somatostatin analogue in a patient with advanced prostate cancer: magnetic resonance imaging with 1H-spectroscopy. European urology 20080301
The effect of luteal phase vaginal estradiol supplementation on the success of in vitro fertilization treatment: a prospective randomized study. Fertility and sterility 20080301
Oral contraceptive pretreatment does not improve outcome in microdose gonadotrophin-releasing hormone agonist protocol among poor responder intracytoplasmic sperm injection patients. Journal of assisted reproduction and genetics 20080301
Comparisons of different dosages of gonadotropin-releasing hormone (GnRH) antagonist, short-acting form and single, half-dose, long-acting form of GnRH agonist during controlled ovarian hyperstimulation and in vitro fertilization. Taiwanese journal of obstetrics & gynecology 20080301
Prospective study of depression and fatigue in men with advanced prostate cancer receiving hormone therapy. Psycho-oncology 20080201
Medical treatment of uterocutaneous fistula with gonadotropin-releasing hormone agonist administration. Obstetrics and gynecology 20080201
Novel combinations of rate-controlling polymers for the release of leuprolide acetate in the colon. Drug delivery 20080201
Adipocytokines, obesity, and insulin resistance during combined androgen blockade for prostate cancer. Urology 20080201
The use of gonadotropin-releasing hormone (GnRH) agonist to induce oocyte maturation after cotreatment with GnRH antagonist in high-risk patients undergoing in vitro fertilization prevents the risk of ovarian hyperstimulation syndrome: a prospective randomized controlled study. Fertility and sterility 20080101
Management of poor responders: can outcomes be improved with a novel gonadotropin-releasing hormone antagonist/letrozole protocol? Fertility and sterility 20080101
Leuprolide--a GnRH agonist--prevents restraint stress-induced immunosuppression via sex steroid-independent peripheral mechanism in mice. International immunopharmacology 20080101
Nanomilled oral testosterone plus dutasteride effectively normalizes serum testosterone in normal men with induced hypogonadism. Journal of andrology 20080101
Nonalcoholic fatty liver disease induced by leuprorelin acetate. Journal of clinical gastroenterology 20080101
Bicalutamide alone prior to brachytherapy achieves cytoreduction that is similar to luteinizing hormone-releasing hormone analogues with less patient-reported morbidity. Urologic oncology 20080101
Evaluation of resistance index in patients with prostate cancer. Anticancer research 20080101
Prostate specific antigen (PSA) may be a poor marker for progression of prostate cancer after treatment with a combination of chemo-hormonal therapies. The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20080101
Disseminated maculopapular eruption caused by leuprorelin acetate. European journal of dermatology : EJD 20080101
The role of GnRH analogues in endometriosis-associated apoptosis and angiogenesis. Gynecologic and obstetric investigation 20080101
Endometriosis involving the rectus abdominis muscle and subcutaneous tissues: fine needle aspiration appearances. Chirurgia (Bucharest, Romania : 1990) 20080101
Hormonal suppression treatment or dietary therapy versus placebo in the control of painful symptoms after conservative surgery for endometriosis stage III-IV. A randomized comparative trial. Fertility and sterility 20071201
Leuprorelin, triptorelin: new indications. Locally advanced prostate cancer: minimally assessed me-toos. Prescrire international 20071201
Leuprolide acetate: a drug of diverse clinical applications. Expert opinion on investigational drugs 20071101
The incidence of aberrant endometrial alphavbeta(3) vitronectin expression in a high risk infertility population: could prolonged GnRH agonist therapy play a role? Journal of assisted reproduction and genetics 20071101
Luteinizing hormone (LH) and estradiol suppression and growth in girls with central precocious puberty: is more suppression better? Are pre-injection LH levels useful in monitoring treatment? Journal of pediatric endocrinology & metabolism : JPEM 20071101
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas. The Cochrane database of systematic reviews 20071017
Duration of testosterone suppression and the risk of death from prostate cancer in men treated using radiation and 6 months of hormone therapy. Cancer 20071015
Massive ascites and hydrothorax after leuprolide acetate administration in a down-regulated woman undergoing assisted reproduction. Fertility and sterility 20071001
Intestinal endometriosis complicated by ileal perforation after initiation of gonadotropin-releasing hormone agonist therapy. Fertility and sterility 20071001
Role of insulin in the hyperandrogenemia of lean women with polycystic ovary syndrome and normal insulin sensitivity. Fertility and sterility 20071001
Efficacy of levamisole on experimental endometriosis. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20071001
The change in the dihydrotestosterone level in the prostate before and after androgen deprivation therapy in connection with prostate cancer aggressiveness using the Gleason score. The Journal of urology 20071001
Zinc-leuprolide complex: preparation, physicochemical characterization and release behaviour from in situ forming implant. Journal of peptide science : an official publication of the European Peptide Society 20071001
Bone density in adolescents treated with a GnRH agonist and add-back therapy for endometriosis. Journal of pediatric and adolescent gynecology 20071001
One-year-old male with accelerated growth and development. Postgraduate medical journal 20071001
The effects of gonadotropin releasing hormone analogue therapy on girls with gonadotropin-dependent precocious puberty. Journal of the Formosan Medical Association = Taiwan yi zhi 20071001
[Granuloma at the injection site of leuprorelin acetate: foreign body reaction to polylactic acid]. Annales de dermatologie et de venereologie 20071001
A prospective assessment of androgen levels in patients with autistic spectrum disorders: biochemical underpinnings and suggested therapies. Neuro endocrinology letters 20071001
Transfusion-dependent anemia after initiation of androgen deprivation therapy for metastatic prostate cancer. Urology 20071001
[Skin reaction induced by subcutaneous injection of LH-RH analogue]. Hinyokika kiyo. Acta urologica Japonica 20071001
The contribution of luteinizing hormone to Alzheimer disease pathogenesis. Clinical medicine & research 20071001
Prevention and treatment of uterine bleeding in hematologic malignancy. European journal of obstetrics, gynecology, and reproductive biology 20070901
Fatal spontaneous tumor lysis syndrome in a patient with metastatic, androgen-independent prostate cancer. Southern medical journal 20070901
A second transient prostate-specific antigen elevation after external-beam radiation therapy and fractionated magnetic resonance imaging-guided high-dose rate brachytherapy boost. Clinical genitourinary cancer 20070901
Luteal phase oestradiol administration in ovarian stimulation cycles with GnRH antagonist is comparable to the GnRH agonist (long) protocol. Journal of assisted reproduction and genetics 20070801
Comparison of FSH flare with and without pretreatment with oral contraceptive pills in poor responders undergoing in vitro fertilization. Fertility and sterility 20070801
Leuprorelin acetate for female patients with newly diagnosed acute leukemia receiving chemotherapy. International journal of hematology 20070801
Injection-site granulomas resulting from the administration of both leuprorelin acetate and goserelin acetate for the treatment of prostatic cancer. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20070801
Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. The Journal of reproductive medicine 20070801
Dosage form development, in vitro release kinetics, and in vitro-in vivo correlation for leuprolide released from an implantable multi-reservoir array. Pharmaceutical research 20070701
Expert opinion on 6-monthly luteinizing hormone-releasing hormone agonist treatment with the single-sphere depot system for prostate cancer. BJU international 20070701
Obesity and treatment of prostate cancer: what is the right dose of Lupron Depot? Clinical cancer research : an official journal of the American Association for Cancer Research 20070701
Bilateral presentation of fibroadenoma with digital fibroma-like inclusions in the male breast. Archives of pathology & laboratory medicine 20070701
Male breast cancer during treatment with leuprolide for prostate cancer. Clinical advances in hematology & oncology : H&O 20070701
Injection-site granulomas due to the administration of leuprorelin acetate for the treatment of prostatic cancer. Fukuoka igaku zasshi = Hukuoka acta medica 20070701
Effects of a depot formulation of the GnRH agonist leuprorelin on the ultrastructure of male rat pituitary gonadotropes. Archives of histology and cytology 20070701
Cell growth effects of leuprolide on cultured endometrioma cells. The Journal of reproductive medicine 20070701
Extension of GnRH agonist through the luteal phase to improve the outcome of intracytoplasmic sperm injection. The Journal of reproductive medicine 20070701
[Endometriosis]. Therapeutische Umschau. Revue therapeutique 20070701
Incidence rate of injection-site granulomas resulting from the administration of luteinizing hormone-releasing hormone analogues for the treatment of prostatic cancer. Yonsei medical journal 20070630
Can biology trump anatomy? Do all node-positive patients with breast cancer need chemotherapy? Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070620
Leuprorelin acetate every-3-months depot versus cyclophosphamide, methotrexate, and fluorouracil as adjuvant treatment in premenopausal patients with node-positive breast cancer: the TABLE study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070620
LHRH antagonist attenuates the effect of fluoxetine on marble-burying behavior in mice. European journal of pharmacology 20070601
Single-dose depot leuprolide is as efficient as daily short-acting leuprolide in ICSI cycles. Human reproduction (Oxford, England) 20070601
[Exacerbation of a schizoaffective psychosis after in vitro fertilization with leuproreline acetate]. Der Nervenarzt 20070601
Determining dosing intervals for luteinizing hormone releasing hormone agonists based on serum testosterone levels: a prospective study. The Journal of urology 20070601
Bath-related headache: a case report. Cephalalgia : an international journal of headache 20070601
High-dose atorvastatin causes regression of endometriotic implants: a rat model. Human reproduction (Oxford, England) 20070501
Luteogenic hormones act through a vascular endothelial growth factor-dependent mechanism to up-regulate alpha 5 beta 1 and alpha v beta 3 integrins, promoting the migration and survival of human luteinized granulosa cells. The American journal of pathology 20070501
Inhibition of cytochrome P-450 C17 enzyme by a GnRH agonist in ovarian follicles from gonadotropin-stimulated rats. American journal of physiology. Endocrinology and metabolism 20070501
A practical approach to precocious puberty. Clinical pediatrics 20070501
Ovarian suppression with a gonadotropin-releasing hormone agonist does not alter insulin-stimulated glucose disposal. Fertility and sterility 20070501
Cushing syndrome associated with prostatic tumor adrenocorticotropic hormone (ACTH) expression after maximal androgen blockade therapy. International journal of urology : official journal of the Japanese Urological Association 20070501
[Ischemic stroke associated with LH-RH analogue (leuprorelin) administration in a young woman]. Rinsho shinkeigaku = Clinical neurology 20070501
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas. The Cochrane database of systematic reviews 20070418
Ovarian ablation or suppression in premenopausal early breast cancer: results from the international adjuvant breast cancer ovarian ablation or suppression randomized trial. Journal of the National Cancer Institute 20070404
Re: Olav Erich Yri, Trine Bjoro and Sophie D. Fossa. Failure to achieve castration levels in patients using leuprolide acetate in locally advanced prostate cancer. Eur urol 2006;49:54-8. European urology 20070401
Increased adiposity enhances intrafollicular estradiol levels in normoandrogenic ovulatory women receiving gonadotropin-releasing hormone analog/recombinant human follicle-stimulating hormone therapy for in vitro fertilization. The Journal of clinical endocrinology and metabolism 20070401
Autism and environmental toxicity. The Lancet. Neurology 20070401
Noninfective cutaneous granuloma with leuprorelin acetate--reality or myth. Urology 20070401
[Dermatitis herpetiformis associated with progesterone contraception]. Annales de dermatologie et de venereologie 20070401
Re: Olav Erich Yri, Trine Bjoro and Sophie D. Fossa. Failure to achieve castration levels in patients using leuprolide acetate in locally advanced prostate cancer. Eur Urol 2006;49:54-58. European urology 20070301
Effect of GnRH analogues on apoptosis and expression of Bcl-2, Bax, Fas and FasL proteins in endometrial epithelial cell cultures from patients with endometriosis and controls. Human reproduction (Oxford, England) 20070301
Rapid suppression of plasma testosterone levels and tumor growth in the dunning rat model treated with degarelix, a new gonadotropin-releasing hormone antagonist. The Journal of pharmacology and experimental therapeutics 20070301
Locally advanced prostate cancer--biochemical results from a prospective phase II study of intermittent androgen suppression for men with evidence of prostate-specific antigen recurrence after radiotherapy. Cancer 20070301
Thyroid outcome during long-term gonadotropin-releasing hormone agonist treatments for idiopathic precocious puberty. The Journal of adolescent health : official publication of the Society for Adolescent Medicine 20070301
Long-term effectiveness of luteinizing hormone-releasing hormone agonist or antiandrogen monotherapy in elderly men with localized prostate cancer (T1-2): a retrospective study. Asian journal of andrology 20070301
Effects of flutamide as a second-line agent for maximum androgen blockade of hormone refractory prostate cancer. International journal of urology : official journal of the Japanese Urological Association 20070301
Gonadal function in low birth weight infants: a pilot study. Journal of pediatric endocrinology & metabolism : JPEM 20070301
Anaphylaxis to leuprolide acetate depot injection during treatment for prostate cancer. Clinical genitourinary cancer 20070301
Efficacy of hormonal manipulation in lymphangioleiomyomatosis. A 20-year-experience in 36 patients. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20070301
Testosterone replacement for hypogonadism after treatment of early prostate cancer with brachytherapy. Cancer 20070201
[Integrated molecular medicine for neuronal and neoplastic disorders]. Seikagaku. The Journal of Japanese Biochemical Society 20070201
Hormone ablation therapy: lightening the load for today's prostate cancer patient. Urologic nursing 20070201
Myocardial infarction complicating the initial phase of an ovarian stimulation protocol. International journal of cardiology 20070131
Phase-sensitive polymer-based controlled delivery systems of leuprolide acetate: in vitro release, biocompatibility, and in vivo absorption in rabbits. International journal of pharmaceutics 20070102
Direct protection by a gonadotropin-releasing hormone analog from doxorubicin-induced granulosa cell damage. Gynecologic and obstetric investigation 20070101
Gonadotropin-releasing hormone agonists reduce the migratory and the invasive behavior of androgen-independent prostate cancer cells by interfering with the activity of IGF-I. International journal of oncology 20070101
Penile length changes in men treated with androgen suppression plus radiation therapy for local or locally advanced prostate cancer. The Journal of urology 20070101
Phase II study of neoadjuvant androgen deprivation followed by external-beam radiotherapy with 9 months of androgen deprivation for intermediate- to high-risk localized prostate cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070101
Bicalutamide 80 mg combined with a luteinizing hormone-releasing hormone agonist (LHRH-A) versus LHRH-A monotherapy in advanced prostate cancer: findings from a phase III randomized, double-blind, multicenter trial in Japanese patients. Prostate cancer and prostatic diseases 20070101
Obesity and sex steroids during gonadotropin-releasing hormone agonist treatment for prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20070101
Early effects of pharmacological androgen deprivation in human prostate cancer. BJU international 20070101
Global update on defining and treating high-risk localized prostate cancer with leuprorelin: a European perspective. BJU international 20070101
Global update on defining and treating high-risk localized prostate cancer with leuprorelin: an Asian perspective. BJU international 20070101
Global update on defining and treating high-risk localized prostate cancer with leuprorelin: a Japanese perspective--the effect of primary androgen deprivation therapy on stage C prostate cancer. BJU international 20070101
Global update on defining and treating high-risk localized prostate cancer with leuprorelin: a USA perspective--identifying men at diagnosis who are at high risk of prostate cancer death after surgery or radiation therapy. BJU international 20070101
Endocrine response to a single injection of goserelin 3.6 mg or leuprolide 3.75 mg in men with prostate cancer. Archives of andrology 20070101
Leuprolide acetate-induced leukocytoclastic vasculitis. Acta obstetricia et gynecologica Scandinavica 20070101
Long-term personalized GnRH agonist therapy without estrogen supplementation for recurrent endometriotic catamenial pneumothorax--case report. Clinical and experimental obstetrics & gynecology 20070101
Intrauterine insemination results in couples requiring extended semen transport time. International journal of fertility and women's medicine 20070101
Leuprolide acetate and central retinal vein occlusion. Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20070101
Prenatal testosterone treatment alters LH and testosterone responsiveness to GnRH agonist in male sheep. Biological research 20070101
Urodynamic parameters and plasma LH/FSH in spayed Beagle bitches before and 8 weeks after GnRH depot analogue treatment. Theriogenology 20061201
Prevention of breast cancer: current state of the science and future opportunities. Expert opinion on investigational drugs 20061201
Recurrent anaphylaxis associated with gonadotropin-releasing hormone analogs: case report and review of the literature. Pharmacotherapy 20061201
A clinical trial of combined anti-androgen and anti-heavy metal therapy in autistic disorders. Neuro endocrinology letters 20061201
Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: development, characterization and interaction with leuprolide. International journal of pharmaceutics 20061115
Key parameters affecting the initial release (burst) and encapsulation efficiency of peptide-containing poly(lactide-co-glycolide) microparticles. International journal of pharmaceutics 20061106
Ganirelix acetate causes a rapid reduction in estradiol levels without adversely affecting oocyte maturation in women pretreated with leuprolide acetate who are at risk of ovarian hyperstimulation syndrome. Human reproduction (Oxford, England) 20061101
Combined prostate brachytherapy and short-term androgen deprivation therapy as salvage therapy for locally recurrent prostate cancer after external beam irradiation. The Journal of urology 20061101
Impact of duration and dose of gonadotrophins on IVF outcomes. Reproductive biomedicine online 20061101
Weight evolution in girls treated for idiopathic central precocious puberty with GnRH analogues. Journal of pediatric endocrinology & metabolism : JPEM 20061101
Stability of poly(D,L-lactide-co-glycolide) and leuprolide acetate in in-situ forming drug delivery systems. Journal of controlled release : official journal of the Controlled Release Society 20061010
GnRH agonist Lupron (leuprolide acetate) pre-treatments prevent ovulation in response to gonadotropin stimulation in the clouded leopard (Neofelis nebulosa). Theriogenology 20061001
Social suppression of cortisol in female marmosets: role of luteinizing hormone/chorionic gonadotropin. General and comparative endocrinology 20061001
Granuloma caused by subcutaneous injection of leuprorelin acetate product: case report and histopathological findings. The Journal of dermatology 20061001
Implications of androgen-deprivation therapy in patients with prostate cancer: A case study. Clinical journal of oncology nursing 20061001
Implantable LHRH agonist for treatment of prostate cancer. Urologic nursing 20061001
[Histological investigation of prostate cancer treated with hormonal agents]. Hinyokika kiyo. Acta urologica Japonica 20061001
Prolongation of growth by treatment of 11-hydroxylase deficiency with depot-leuprolide, growth hormone, and hydrocortisone. Journal of pediatric endocrinology & metabolism : JPEM 20061001
[Breast cancer]. Nihon rinsho. Japanese journal of clinical medicine 20060928
Effect of a long acting GnRH analogue or placebo on plasma LH/FSH, urethral pressure profiles and clinical signs of urinary incontinence due to Sphincter mechanism incompetence in bitches. Theriogenology 20060915
Ovarian suppression with gonadotropin-releasing hormone agonist reduces whole body protein turnover in women. American journal of physiology. Endocrinology and metabolism 20060901
Re: Olav Erich Yri, Trine Bjoro and Sophie D. Fossa. Failure to achieve castration levels in patients using leupoprolide acetate in locally advanced prostate cancer. Eur Urol 2006;49:54-8. European urology 20060901
Effects of treatment with leuprolide acetate depot on working memory and executive functions in young premenopausal women. Psychoneuroendocrinology 20060901
Egg binding in a cockatiel (Nymphicus hollandicus). The veterinary clinics of North America. Exotic animal practice 20060901
Effect of gonadotropin-releasing hormone agonist on a uterine arteriovenous malformation. Obstetrics and gynecology 20060901
Anabolic steroid and gonadotropin releasing hormone analog combined treatment increased pubertal height gain and adult height in two children who entered puberty with short stature. Journal of pediatric endocrinology & metabolism : JPEM 20060901
The effect of androgen deprivation therapy on fasting serum lipid and glucose parameters. The Journal of urology 20060801
Perinatal outcome of pregnancies after inadvertent exposure to gonadotrophin-releasing hormone analogue. The Australian & New Zealand journal of obstetrics & gynaecology 20060801
Chronic vulvovaginal pruritus treated successfully with GnRH analogue. Postgraduate medical journal 20060801
Leuprolide acetate plus aromatase inhibition for male breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060720
Final results of the Canadian prospective phase II trial of intermittent androgen suppression for men in biochemical recurrence after radiotherapy for locally advanced prostate cancer: clinical parameters. Cancer 20060715
Treatment with leuprolide acetate and hormonal add-back for up to 10 years in stage IV endometriosis patients with chronic pelvic pain. Fertility and sterility 20060701
Leuprorelin acetate affects ERK1/2 activity in prostate cancer cells. International journal of oncology 20060701
Combination therapy using LHRH and somatostatin analogues plus dexamethasone in androgen ablation refractory prostate cancer patients with bone involvement: a bench to bedside approach. Expert opinion on investigational drugs 20060701
[8-month neoadjuvant hormonal therapy before radical prostatectomy for high-risk prostate cancer]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20060701
[Effectiveness of Leuprolide acetate therapy every three months in central precocious puberty]. Revista medica de Chile 20060701
[Sexual precocity]. Nihon rinsho. Japanese journal of clinical medicine 20060628
[Hypergonadism]. Nihon rinsho. Japanese journal of clinical medicine 20060628
[Premenstrual syndrome (PMS)]. Nihon rinsho. Japanese journal of clinical medicine 20060628
Follicle luteinization in hyperandrogenic follicles of polycystic ovary syndrome patients undergoing gonadotropin therapy for in vitro fertilization. The Journal of clinical endocrinology and metabolism 20060601
Modification of the tri-phasic drug release pattern of leuprolide acetate-loaded poly(lactide-co-glycolide) microparticles. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060601
Inhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by leuprorelin, a luteinizing hormone-releasing hormone agonist. Cancer science 20060601
Gonadotropin-releasing hormone antagonists increase follicular fluid insulin-like growth factor-I and vascular endothelial growth factor during ovarian stimulation cycles. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20060601
Pituitary desensitization for eight weeks after the administration of two distinct gonadotrophin-releasing hormone agonists. European journal of obstetrics, gynecology, and reproductive biology 20060501
Sequential comparisons of one-month and three-month depot leuprolide regimens in central precocious puberty. The Journal of clinical endocrinology and metabolism 20060501
Adverse effects to quality of life arising from treatment can recover with intermittent androgen suppression in men with prostate cancer. European journal of cancer (Oxford, England : 1990) 20060501
Editorial: does lupron dosage make a difference in outcome when treating children with precocious puberty? The Journal of clinical endocrinology and metabolism 20060501
Preoperative treatment of uterine leiomyomas: clinical findings and expression of transforming growth factor-beta3 and connective tissue growth factor. Journal of the Society for Gynecologic Investigation 20060501
Failure of gonadotropin-releasing hormone agonists with and without sterile abscess formation at depot sites: insight into mechanisms? Urology 20060501
Intestinal endometriosis without evident pelvic foci treated with gonadotropin-releasing hormone agonist. European journal of obstetrics, gynecology, and reproductive biology 20060401
Final height in girls with central idiopathic precocious puberty treated with gonadotropin-releasing hormone analog and oxandrolone. The Journal of clinical endocrinology and metabolism 20060401
Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice. Biochimica et biophysica acta 20060401
Chronic, programmed polypeptide delivery from an implanted, multireservoir microchip device. Nature biotechnology 20060401
Leuprolide acetate is a familiar drug that may modify sex-offender behaviour: the urologist's role. BJU international 20060401
Effect of gonadotropin-releasing hormone agonist and antagonist on proliferation and apoptosis of human luteinized granulosa cells. Fertility and sterility 20060401
Monoamines and neurosteroids in sexual function during induced hypogonadism in healthy men. Archives of general psychiatry 20060401
Effect of a new leuprorelin formulation on testosterone levels in patients with advanced prostate cancer. Current medical research and opinion 20060401
[An outline of GnRH analogue]. Nihon rinsho. Japanese journal of clinical medicine 20060401
[GnRH analogues in the management of uterine leiomyoma]. Nihon rinsho. Japanese journal of clinical medicine 20060401
[Clinical applications of GnRHa in breast cancer]. Nihon rinsho. Japanese journal of clinical medicine 20060401
[Prostate cancer]. Nihon rinsho. Japanese journal of clinical medicine 20060401
[Precocious puberty]. Nihon rinsho. Japanese journal of clinical medicine 20060401
[Prevention of anticancer drug-induced premature ovarian failure]. Nihon rinsho. Japanese journal of clinical medicine 20060401
[Anti-tumor effects of GnRH analogs in gynecological cancers]. Nihon rinsho. Japanese journal of clinical medicine 20060401
[Precocious puberty]. Nihon rinsho. Japanese journal of clinical medicine 20060401
Successful management of vesicouterine fistula by luteinizing hormone-releasing hormone analog. International journal of urology : official journal of the Japanese Urological Association 20060401
Too young to grow. Diagnosis and treatment of precocious puberty. Advance for nurse practitioners 20060401
Induction of fertile oestrus in bitches by an intranasal spray of gonadotrophin-releasing hormone agonist. The Veterinary record 20060318
Mutant androgen receptor accumulation in spinal and bulbar muscular atrophy scrotal skin: a pathogenic marker. Annals of neurology 20060301
Recovery of serum testosterone after neoadjuvant androgen deprivation therapy and radical radiotherapy in localized prostate cancer. BJU international 20060301
Discovery of a pituitary adenoma following a gonadotropin-releasing hormone agonist in a patient with prostate cancer. International journal of urology : official journal of the Japanese Urological Association 20060301
[Treatment of sex offenders with leuprorelin]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20060223
In situ forming microparticle system for controlled delivery of leuprolide acetate: influence of the formulation and processing parameters. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060201
Hyperstimulation and a gonadotropin-releasing hormone agonist modulate ovarian vascular permeability by altering expression of the tight junction protein claudin-5. Endocrinology 20060201
GnRH agonists and antagonists decrease the metastatic progression of human prostate cancer cell lines by inhibiting the plasminogen activator system. Oncology reports 20060201
A 12-month clinical study of LA-2585 (45.0 mg): a new 6-month subcutaneous delivery system for leuprolide acetate for the treatment of prostate cancer. The Journal of urology 20060201
Dermatitis herpetiformis associated with administration of a gonadotropin-releasing hormone analog. Journal of the American Academy of Dermatology 20060201
[Two cases of stage IV breast cancer with severe hypercalcemia]. Gan to kagaku ryoho. Cancer & chemotherapy 20060201
[A case of prostatic cancer discovered from lung metastatic lesions]. Hinyokika kiyo. Acta urologica Japonica 20060201
Subcutaneous injection of depot medroxyprogesterone acetate compared with leuprolide acetate in the treatment of endometriosis-associated pain. Fertility and sterility 20060201
Impact of leuprolide acetate on luteal phase function in women undergoing controlled ovarian hyperstimulation and intrauterine insemination. Fertility and sterility 20060201
Decrease of genital organ weights and plasma testosterone levels in rats following oral administration of leuprolide microemulsion. International journal of pharmaceutics 20060113
Influence of the poly(lactide-co-glycolide) type on the leuprolide release from in situ forming microparticle systems. Journal of controlled release : official journal of the Controlled Release Society 20060110
Synthesis, liposomal formulation and thermal effects on phospholipid bilayers of leuprolide. Journal of peptide science : an official publication of the European Peptide Society 20060101
Testicular germ cell tumors exhibit evidence of hormone dependence. International journal of cancer 20060101
Subcutaneous depot medroxyprogesterone acetate versus leuprolide acetate in the treatment of endometriosis-associated pain. Human reproduction (Oxford, England) 20060101
Failure to achieve castration levels in patients using leuprolide acetate in locally advanced prostate cancer. European urology 20060101
Preliminary investigation of the nasal delivery of liposomal leuprorelin acetate for contraception in rats. The Journal of pharmacy and pharmacology 20060101
Risk of clinical fractures after gonadotropin-releasing hormone agonist therapy for prostate cancer. The Journal of urology 20060101
Treatment with gonadotropin-releasing hormone (GnRH) antagonists in women suppressed with GnRH agonist may avoid cycle cancellation in patients at risk for ovarian hyperstimulation syndrome. Fertility and sterility 20060101
Discovery of a pituitary adenoma following treatment with a gonadotropin-releasing hormone agonist in a patient with prostate cancer. International journal of urology : official journal of the Japanese Urological Association 20060101
Granulomas induced by subcutaneous injection of leuprorelin acetate. The Journal of dermatology 20060101
Central precocious puberty in a girl with Williams syndrome: the result of treatment with GnRH analogue. European journal of medical genetics 20060101
Enhanced expression of heat shock protein 27 following neoadjuvant hormonal therapy is associated with poor clinical outcome in patients undergoing radical prostatectomy for prostate cancer. Anticancer research 20060101
Effect of leuprolide and cetrorelix on cell growth, apoptosis, and GnRH receptor expression in primary cell cultures from human prostate carcinoma. Cancer investigation 20060101
Pituitary apoplexy after leuprolide. Pituitary 20060101
The limited significance of a longer duration of neoadjuvant hormonal therapy prior to radical prostatectomy for high-risk prostate cancer in Japanese men. Urologia internationalis 20060101
Depot leuprorelin acetate-induced granulomas manifested as persistent suppurative nodules. Acta dermato-venereologica 20060101
The prognostic importance of prostate specific antigen in the monitorisation of patients undergoing maximum androgen blockade for metastatic prostate cancer. International urology and nephrology 20060101
Role of androgen ablation with low-dose-rate brachytherapy in the treatment of prostate cancer. Clinical drug investigation 20060101
MEMS fabricated chip for an implantable drug delivery device. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20060101
Defining biochemical failure after radiotherapy with and without androgen deprivation for prostate cancer. International journal of radiation oncology, biology, physics 20051201
Re: A prospective analysis of the time to normalization of serum androgens following 6 months of androgen deprivation therapy in patients on a randomized phase III clinical trial using limited hormonal therapy. The Journal of urology 20051201
Injection systems for two luteinising hormone-releasing hormone agonists: a comparative assessment of administration times and nurses' perceptions. European journal of oncology nursing : the official journal of European Oncology Nursing Society 20051201
Effect on insulin sensitivity of Implanon vs. GnRH agonist in women with endometriosis. Contraception 20051201
Endoscopic diagnosis and management of ureteral endometriosis. Journal of endourology 20051201
Leuprolide acetate suppresses pedophilic urges and arousability. Archives of sexual behavior 20051201
Sleep, breathing, and menopause: the effect of fluctuating estrogen and progesterone on sleep and breathing in women. Gender medicine 20051201
First report on the efficacy of l-alanine-based in situ-forming implants for the long-term parenteral delivery of drugs. Journal of controlled release : official journal of the Controlled Release Society 20051128
Effect of GnRH analogs on the expression of TrkA and p75 neurotrophin receptors in primary cell cultures from human prostate adenocarcinoma. The Prostate 20051101
Pure red cell aplasia in a prostate cancer patient treated with leuprolide acetate and chlormadinone acetate. International journal of urology : official journal of the Japanese Urological Association 20051101
Testosterone suppression of CRH-stimulated cortisol in men. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051001
Comparison of embryo implantation in Wistar rats that underwent ovarian stimulation using exogenous gonadotropins associated with cetrorelix acetate or leuprolide acetate. Fertility and sterility 20051001
Insulin resistance as an adverse effect of leuprolide and bicalutamide treatment. The journals of gerontology. Series A, Biological sciences and medical sciences 20051001
Evaluation of remotely delivered leuprolide acetate as a contraceptive agent in female elk (Cervus elaphus nelsoni). Journal of wildlife diseases 20051001
[Are all LH-RH analogues equally effective in prostate cancer?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050922
Clinical outcome of oral uracil/tegafur (UFT) therapy for patients with hormone refractory prostate cancer. Oncology reports 20050901
Long-term side-effects of intermittent androgen suppression therapy in prostate cancer: results of a phase II study. BJU international 20050901
Late radiotherapy toxicity after prostate cancer treatment: influence of hormonal therapy. Urology 20050901
Use of a gonadotropin-releasing hormone analog for protection against premature ovarian failure during cyclophosphamide therapy in women with severe lupus. Arthritis and rheumatism 20050901
A preliminary pharmacokinetic study of liposomal leuprolide dry powder inhaler: a technical note. AAPS PharmSciTech 20050901
Comparison of artificial neural network and multiple linear regression in the optimization of formulation parameters of leuprolide acetate loaded liposomes. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050805
Luteinizing hormone-releasing hormone analog treatment for a criminal sexual habit caused by male precocious puberty. Pediatrics international : official journal of the Japan Pediatric Society 20050801
Leuprolide acetate given by a subcutaneous extended-release injection: less of a pain? Expert review of anticancer therapy 20050801
The experiences of men receiving androgen deprivation treatment for prostate cancer: a qualitative study. The Canadian journal of urology 20050801
Randomized clinical trial of a levonorgestrel-releasing intrauterine system and a depot GnRH analogue for the treatment of chronic pelvic pain in women with endometriosis. Human reproduction (Oxford, England) 20050701
Ovarian function during puberty in girls with type 1 diabetes mellitus: response to leuprolide. The Journal of clinical endocrinology and metabolism 20050701
Effectiveness of cyproterone acetate in achieving castration and preventing luteinizing hormone releasing hormone analogue induced testosterone surge in patients with prostate cancer. The Journal of urology 20050701
Expression of proliferating cell nuclear antigen and bcl-2 during a pseudomenopausal state induced by presurgical treatment of uterine leiomyomas with gonadotropin-releasing hormone analogues plus tibolone. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 20050701
Antral follicle assessment after down-regulation may be a useful tool for predicting pregnancy loss in in vitro fertilization pregnancies. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050701
[Clinical trial on the effectiveness and safety of triptorelin in treatment of uterine leiomyoma]. Zhonghua fu chan ke za zhi 20050701
[Surgical management of inflammatory granuloma which developed following subcutaneous injection of leuprorelin acetate: a case report]. Hinyokika kiyo. Acta urologica Japonica 20050701
Empirical therapy with leuprorelin acetate for endometriosis in the United States. Drugs of today (Barcelona, Spain : 1998) 20050701
Undetectable prostate specific antigen at 6-12 months: a new marker for early success in hormonally treated patients after prostate brachytherapy. Cancer 20050615
Tumor control outcomes of patients treated with trimodality therapy for locally advanced prostate cancer. Urology 20050601
Issues to consider in the assessment and treatment of paraphilic patients. The Journal of clinical psychiatry 20050601
Gonadotropin-releasing hormone retards doxorubicin-induced apoptosis and serine/threonine phosphatase inhibition in ovarian cancer cells. Oncology reports 20050501
A prospective analysis of the time to normalization of serum androgens following 6 months of androgen deprivation therapy in patients on a randomized phase III clinical trial using limited hormonal therapy. The Journal of urology 20050501
Pregnancy outcomes in in vitro fertilization cycles with serum estradiol drop prior to human chorionic gonadotropin. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20050501
Acute depletion of murine primordial follicle reserve by gonadotropin-releasing hormone antagonists. Fertility and sterility 20050501
A randomized prospective study of microdose leuprolide versus ganirelix in in vitro fertilization cycles for poor responders. Fertility and sterility 20050501
Fibroids (uterine myomatosis, leiomyomas). American family physician 20050501
Leuprorelin acetate granulomas: case reports and review of the literature. The British journal of dermatology 20050501
Tumour staging using magnetic resonance imaging in clinically localised prostate cancer: relationship to biochemical outcome after neo-adjuvant androgen deprivation and radical radiotherapy. Clinical oncology (Royal College of Radiologists (Great Britain)) 20050501
Estrogen dermatitis responding to leuprolide acetate. The Journal of dermatology 20050501
LC determination of leuprolide component amino acids in injectable solution by phanquinone pre-column derivatization labelling procedure. Journal of pharmaceutical and biomedical analysis 20050429
Docetaxel followed by hormone therapy in men experiencing increasing prostate-specific antigen after primary local treatments for prostate cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050420
Effectiveness of adjuvant intermittent endocrine therapy following neoadjuvant endocrine therapy and external beam radiation therapy in men with locally advanced prostate cancer. The Prostate 20050401
A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: effects on serum markers of bone turnover, insulin-like growth factor-I, and osteoclastogenic mediators. The Journal of clinical endocrinology and metabolism 20050401
The treatment of menorrhagia in female stem cell transplant recipients. Bone marrow transplantation 20050401
Leuprolide acetate treatment with and without coadministration of tibolone in premenopausal women with menstrual cycle-related irritable bowel syndrome. Fertility and sterility 20050401
[A case of recurrent breast cancer with multiple lung, adrenal, inferior vena cava tumor thrombus and bone metastases successfully treated with 5'-DFUR and hormonal therapy]. Gan to kagaku ryoho. Cancer & chemotherapy 20050401
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Lipid, glucose and homocysteine metabolism in women treated with a GnRH agonist with or without raloxifene. Human reproduction (Oxford, England) 20040201
Pattern of proliferative index (Ki-67) after anti-androgen manipulation reflects the ability of irradiation to control prostate cancer. American journal of clinical oncology 20040201
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The effect of a gonadotrophin-releasing hormone analogue as first-line management in cyclical pelvic pain. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20040101
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Preoperative leuprolide acetate combined with Interceed* optimally reduces uterine adhesions and fibrosis in a rabbit model. Fertility and sterility 20040101
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Superior anti-tumor efficacy of bicalutamide 80 mg in combination with a luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist monotherapy as first-line treatment for advanced prostate cancer: interim results of a randomized study in Japanese patients. Japanese journal of clinical oncology 20040101
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Prostate volume before and after permanent prostate brachytherapy in patients receiving neoadjuvant androgen suppression. Cancer journal (Sudbury, Mass.) 20040101
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Restoration of spermatogenesis in dibromochloropropane (DBCP)-treated rats by hormone suppression. Toxicological sciences : an official journal of the Society of Toxicology 20031201
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Serum leptin levels in patients with premenstrual syndrome treated with GnRH analogues alone and in association with tibolone. Clinical endocrinology 20031201
Complications of androgen-deprivation therapy for prostate cancer. Clinical prostate cancer 20031201
The expression of Smads and transforming growth factor beta receptors in leiomyoma and myometrium and the effect of gonadotropin releasing hormone analogue therapy. Molecular and cellular endocrinology 20031114
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The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer. The Journal of urology 20031101
Effect of gonadotropin-releasing hormone agonist and medroxyprogesterone acetate on calcium metabolism: a prospective, randomized, double-blind, placebo-controlled, crossover trial. Fertility and sterility 20031101
Endometriosis and its treatment with danazol or lupron in relation to ovarian cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20031101
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Cholestatic jaundice as a paraneoplastic manifestation of prostate adenocarcinoma. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20031101
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Enhanced polyadenosine diphosphate-ribosylation in gonadotropin-releasing hormone agonist-treated uterine leiomyoma. The Journal of clinical endocrinology and metabolism 20031001
Treatment-associated serum FSH levels in very poor responders to ovarian stimulation. Journal of assisted reproduction and genetics 20031001
Case 1. Aggressive angiomyxoma of the pelvis: response to luteinizing hormone-releasing hormone agonist. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030915
Cytogenetic analysis of uterine leiomyoma: the size, histopathology and GnRHa-response in relation to chromosome karyotype. European journal of obstetrics, gynecology, and reproductive biology 20030910
Effect of GnRH analogues on apoptosis and release of interleukin-1beta and vascular endothelial growth factor in endometrial cell cultures from patients with endometriosis. Human reproduction (Oxford, England) 20030901
Gonadotropin-releasing hormone agonist induces apoptosis and reduces cell proliferation in eutopic endometrial cultures from women with endometriosis. Fertility and sterility 20030901
Endometrial HOXA10 expression after controlled ovarian hyperstimulation with recombinant follicle-stimulating hormone. Fertility and sterility 20030901
Contemporary management of fibroids. Annals of the Academy of Medicine, Singapore 20030901
Signet-ring cell carcinoma of the prostate effectively treated with maximal androgen blockade. International journal of urology : official journal of the Japanese Urological Association 20030801
Comparative efficacy of triptorelin pamoate and leuprolide acetate in men with advanced prostate cancer. BJU international 20030801
An eight-month clinical study of LA-2575 30.0 mg: a new 4-month, subcutaneous delivery system for leuprolide acetate in the treatment of prostate cancer. Urology 20030801
Pharmacotherapy of paraphilias with long-acting agonists of luteinizing hormone-releasing hormone: a systematic review. The Journal of clinical psychiatry 20030801
Upregulation of HER-2/neu by ovarian ablation: results of a randomized trial comparing leuprorelin to CMF as adjuvant therapy in node-positive breast cancer patients. Breast cancer research and treatment 20030801
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Clinical outcome of using ganirelix acetate versus a 4-day follicular phase leuprolide acetate protocol in unselected women undergoing in vitro fertilization. Fertility and sterility 20030701
Hormone therapy in men-increased risk of cardiac allograft rejection? The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030701
Osteoporosis associated with the treatment of paraphilias: a clinical review of seven case reports. Journal of forensic sciences 20030701
Long-acting depot formulation of luprolide acetate as a method of hypothalamic down regulation for controlled ovarian hyperstimulation and oocyte production in Macaca fascicularis. Biology of reproduction 20030601
Increment of murine spermatogonial cell number by gonadotropin-releasing hormone analogue is independent of stem cell factor c-kit signal. Biology of reproduction 20030601
Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy. Nature medicine 20030601
Neoadjuvant doxil chemotherapy prior to androgen ablation plus radiotherapy for high-risk localized prostate cancer: feasibility and toxicity. American journal of clinical oncology 20030601
Leuprorelin: a leading role in advanced prostate cancer therapy. Hospital medicine (London, England : 1998) 20030601
Congenital HIV infection and precocious puberty. Journal of pediatric endocrinology & metabolism : JPEM 20030601
[Two cases of non-functional gonadotroph adenoma pituitary apoplexy following GnRH-agonist treatment revealing gonadotroph adenoma and pseudopituitary apoplexy after GnRH administration]. Annales d'endocrinologie 20030601
Changes in serum leptin levels during GnRH agonist therapy. Endocrine journal 20030601
Steroidogenic acute regulatory protein in ovarian follicles of gonadotropin-stimulated rats is regulated by a gonadotropin-releasing hormone agonist. Biology of reproduction 20030501
The impact of prostate volume following neoadjuvant androgen deprivation on quality of life and voiding symptoms in patients undergoing permanent prostate brachytherapy. European urology 20030501
The evaluation and management of hirsutism. Obstetrics and gynecology 20030501
Lower levels of inhibin A and pro-alphaC during the luteal phase after triggering oocyte maturation with a gonadotropin-releasing hormone agonist versus human chorionic gonadotropin. Fertility and sterility 20030501
Gonadotropin-releasing hormone agonist and danazol normalize aromatase cytochrome P450 expression in eutopic endometrium from women with endometriosis, adenomyosis, or leiomyomas. Fertility and sterility 20030301
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Immunohistochemical detection of insulin-like growth factor type I receptor and uterine volume changes in gonadotropin-releasing hormone analog-treated uterine leiomyomas. American journal of obstetrics and gynecology 20030301
Release of small water-soluble drugs from multiblock copolymer microspheres: a feasibility study. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20030301
Effects on bone mineral density of gonadotropin releasing hormone analogs used in the treatment of central precocious puberty. Journal of pediatric endocrinology & metabolism : JPEM 20030301
Treatment of leuprolide-induced depression with intramuscular testosterone: a case report. The Journal of clinical psychiatry 20030301
A longer duration of neo-adjuvant combined androgen blockade prior to radical prostatectomy may lead to lower tumour volume of localised prostate cancer. European urology 20030201
Protecting spermatogonia from apoptosis induced by doxorubicin using the luteinizing hormone-releasing hormone analog leuprorelin. International journal of urology : official journal of the Japanese Urological Association 20030201
Atypical endometrial hyperplasia in an 18-year-old woman. Archives of gynecology and obstetrics 20030201
Use of complementary and alternative medicine by patients with localized prostate carcinoma: study at a single institute in Japan. International journal of clinical oncology 20030201
Neoadjuvant androgen deprivation and prostate gland shrinkage during conformal radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030201
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[Treatment of premenopausal patients with advanced or recurrent breast cancer by chemical ablation]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20030201
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Serum concentrations of growth factors in women with and without endometriosis: the action of anti-endometriosis medicines. International immunopharmacology 20030101
Giant multilocular cystadenoma of the prostate responsive to GnRH antagonists. Urology 20030101
Leuprorelin acetate granulomas: recurrent subcutaneous nodules mimicking metastatic deposits at injections sites. BJU international 20030101
Clinical management of low ovarian response to stimulation for IVF: a systematic review. Human reproduction update 20030101
Can we decrease breakthrough bleeding in patients with endometriosis on norethindrone acetate? International journal of fertility and women's medicine 20030101
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Neoadjuvant therapy before radical prostatectomy in high-risk localized prostate cancer: defining appropriate endpoints. Urologic oncology 20030101
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Highly purified human-derived follicle-stimulating hormone (Bravelle) has equivalent efficacy to follitropin-beta (Follistim) in infertile women undergoing in vitro fertilization. Reproductive biology and endocrinology : RB&E 20030101
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Psychosocial and biological treatment considerations for the paraphilic and nonparaphilic sex offender. The journal of the American Academy of Psychiatry and the Law 20030101
Sex hormones, neurotransmitters, and psychopharmacological treatments in men with paraphilic disorders. Journal of child sexual abuse 20030101
Effectiveness of combined GnRH analogue plus raloxifene administration in the treatment of uterine leiomyomas: a prospective, randomized, single-blind, placebo-controlled clinical trial. Human reproduction (Oxford, England) 20021201
Effects of GnRH analogues, 'add-back' steroid therapy, antiestrogen and antiprogestins on leiomyoma and myometrial smooth muscle cell growth and transforming growth factor-beta expression. Molecular human reproduction 20021201
Luteinising hormone releasing hormone analogues in the treatment of prostate cancer. Expert opinion on pharmacotherapy 20021201
Pharmacokinetics, safety and tolerability of three dosage regimens of buccal adhesive testosterone tablets in healthy men suppressed with leuprorelin. The Journal of endocrinology 20021201
Comparison of leuprolide acetate and triptorelin in assisted reproductive technology cycles: a prospective, randomized study. Fertility and sterility 20021201
Exacerbation of ovarian hyperstimulation by leuprolide reveals a gonadotroph adenoma. Fertility and sterility 20021201
[Characteristics, effects, side effects of the LH-RH agonist]. Nihon rinsho. Japanese journal of clinical medicine 20021201
[Time to normalization of testosterone after withdrawal of long time LH-RH agonist therapy in prostate cancer]. Nihon rinsho. Japanese journal of clinical medicine 20021201
[Total androgen blockade]. Nihon rinsho. Japanese journal of clinical medicine 20021201
[The trends in new drugs for the prostate cancer]. Nihon rinsho. Japanese journal of clinical medicine 20021201
Effect of ovaric hyper-stimulation on blood lymphocyte subpopulations, cytokines, leptin and nitrite among patients with unexplained infertility. American journal of reproductive immunology (New York, N.Y. : 1989) 20021201
[Clinical effects of a 3-month formulation LH-RH agonist, TAP-144-SR (3M) in prostate cancer patients]. Hinyokika kiyo. Acta urologica Japonica 20021201
[Clinical effects of a 3-month formulation LH-RH agonist, TAP-144-SR (3M) in prostate cancer patients]. Hinyokika kiyo. Acta urologica Japonica 20021201
Testosterone suppression in men with prostate cancer is associated with increased arterial stiffness. The aging male : the official journal of the International Society for the Study of the Aging Male 20021201
GnRH agonist inhibits human telomerase reverse transcriptase mRNA expression in endometrial cancer cells. International journal of molecular medicine 20021101
In regard to Padula et al., normalization of serum testosterone levels in patients treated with neoadjuvant hormonal therapy and three-dimensional conformal radiotherapy for prostate cancer. IJROBP 2002;52: 439-443. International journal of radiation oncology, biology, physics 20021101
No rules without exception: a long-term complete remission observed in a study using a LH-RH agonist in platinum-refractory ovarian cancer. European journal of cancer (Oxford, England : 1990) 20021101
The effects of gender and gonadal steroids on the neuroendocrine and temperature response to m-chlorophenylpiperazine in leuprolide-induced hypogonadism in women and men. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021101
A six-month, open-label study assessing a new formulation of leuprolide 7.5 mg for suppression of testosterone in patients with prostate cancer. Clinical therapeutics 20021101
Estrogen effects on osmotic regulation of AVP and fluid balance. American journal of physiology. Endocrinology and metabolism 20021001
Laser-assisted ICSI: a novel approach to obtain higher oocyte survival and embryo quality rates. Human reproduction (Oxford, England) 20021001
Unusual anti-angiogenic effect of combined hormonal blockade. The Journal of urology 20021001
Raloxifene administration in women treated with gonadotropin-releasing hormone agonist for uterine leiomyomas: effects on bone metabolism. The Journal of clinical endocrinology and metabolism 20021001
Fas and its ligand, caspases, and bcl-2 expression in gonadotropin-releasing hormone agonist-treated uterine leiomyoma. The Journal of clinical endocrinology and metabolism 20021001
The acid-labile subunit of human ternary insulin-like growth factor-binding protein complex in girls with central precocious puberty before and during gonadotropin-releasing hormone analog therapy. The Journal of clinical endocrinology and metabolism 20021001
Leuprolide-induced myopathy. Journal of the American Geriatrics Society 20021001
Effect of prolonged gonadotropin-releasing hormone agonist therapy on the outcome of in vitro fertilization-embryo transfer in patients with endometriosis. Fertility and sterility 20021001
Laparoscopic ovarian cystectomy of endometriomas does not affect the ovarian response to gonadotropin stimulation. Fertility and sterility 20021001
Neoadjuvant hormonal therapy prior to radical prostatectomy: evaluation of pathological downstaging and biochemical relapse. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20021001
Altered cognitive function in men treated for prostate cancer with luteinizing hormone-releasing hormone analogues and cyproterone acetate: a randomized controlled trial. BJU international 20020901
Serum testosterone suppression and potential for agonistic stimulation during chronic treatment with monthly and 3-month depot formulations of leuprolide acetate for advanced prostate cancer. The Journal of urology 20020901
A clinical study of 22.5 mg. La-2550: A new subcutaneous depot delivery system for leuprolide acetate for the treatment of prostate cancer. The Journal of urology 20020901
Recovery of spermatogenesis by high dose gonadotropin-releasing hormone analogue treatment in rat cryptorchid testis after orchiopexy. The Journal of urology 20020901
Immunohistochemical study of a case of uterine leiomyoma showing massive lymphoid infiltration and localized vasculitis after LH-RH derivant treatment. Histopathology 20020901
Characterization of the solution conformations of leuprolide acetate. The journal of peptide research : official journal of the American Peptide Society 20020901
Treatment of central precocious puberty by subcutaneous injections of leuprorelin 3-month depot (11.25 mg). The Journal of clinical endocrinology and metabolism 20020901
Comparison of metaphase II oocytes after stimulation with recombinant follicle-stimulating hormone and urinary follicle-stimulating hormone in a pituitary down-regulation regimen. Fertility and sterility 20020901
No rules without exception: long-term complete remission observed in a study using a LH-RH agonist in platinum-refractory ovarian cancer. Gynecologic oncology 20020901
Modifying the release of leuprolide from spray dried OED microparticles. Journal of controlled release : official journal of the Controlled Release Society 20020821
Short-term suppression of ovarian function and immune measures in healthy women. Psychoneuroendocrinology 20020801
Leuprorelin acetate granulomas: recurrent subcutaneous nodules mimicking metastatic deposits at injection sites. BJU international 20020801
Effects of a gonadotropin-releasing hormone agonist on rat ovarian follicle apoptosis: regulation by epidermal growth factor and the expression of Bcl-2-related genes. Biology of reproduction 20020801
Comparison of the reduction of postoperative adhesions by two barriers, one solution, and two pharmacologic agents in the rat uterine model. Fertility and sterility 20020801
Effect of in vivo GnRH agonist and GnRH antagonist on hCG and insulin-stimulated progesterone production by human granulosa-lutein cells in vitro. Journal of assisted reproduction and genetics 20020801
Hormonal therapy of prostate cancer. Seminars in urologic oncology 20020801
Clinical evaluation of three different gonadotrophin-releasing hormone analogues in an IVF programme: a prospective study. European journal of obstetrics, gynecology, and reproductive biology 20020710
Resistance to luteinizing hormone releasing hormone agonist therapy for metastatic prostate cancer. The Journal of urology 20020701
Bone metabolism in postmenopausal women who were treated with a gonadotropin-releasing hormone agonist and tibolone. Fertility and sterility 20020701
Pulmonary endometriosis in a patient with unicornuate uterus and noncommunicating rudimentary horn. Fertility and sterility 20020701
Can combined androgen blockade provide long-term control or possible cure of localized prostate cancer? Urology 20020701
[Prostatic adenocarcinoma revealed by disseminated intravascular coagulation and fibrinolysis]. Annales d'urologie 20020701
Comparison between a single dose of goserelin (depot) and multiple daily doses of leuprolide acetate for pituitary suppression in IVF treatment: a clinical endocrinological study of the ovarian response. Journal of assisted reproduction and genetics 20020701
Impact of six months of GnRH agonist therapy for endometriosis. Is there an age-related effect on bone mineral density? The Journal of reproductive medicine 20020701
Changes in bone mineral density, lean body mass and fat content as measured by dual energy x-ray absorptiometry in patients with prostate cancer without apparent bone metastases given androgen deprivation therapy. The Journal of urology 20020601
Prostate volume reduction with androgen deprivation therapy before interstitial brachytherapy. The Journal of urology 20020601
Comparison of the efficacy and safety of a highly purified human follicle-stimulating hormone (Bravelle) and recombinant follitropin-beta for in vitro fertilization: a prospective, randomized study. Fertility and sterility 20020601
Hormonal manipulation in women with chronic, cyclic irritable bladder symptoms and pelvic pain. American journal of obstetrics and gynecology 20020601
Leuprorelin acetate in prostate cancer: a European update. International journal of clinical practice 20020601
Neoadjuvant androgen withdrawal prior to external radiotherapy for locally advanced adenocarcinoma of the prostate. International journal of urology : official journal of the Japanese Urological Association 20020601
Inverse relationship between the changes in trunk lean and fat mass during gonadotropin-releasing hormone agonist therapy. Maturitas 20020520
Postmenopausal hyperthecosis: functional dysregulation of androgenesis in climacteric ovary. Obstetrics and gynecology 20020501
Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis: long-term follow-up. Obstetrics and gynecology 20020501
Pharmacotherapy of paraphilias with luteinizing hormone-releasing hormone agonists. Archives of general psychiatry 20020501
Outcome predictions for patients with metastatic prostate cancer. Seminars in urologic oncology 20020501
Eligard. Tiny implant fights prostate cancer. Nursing 20020501
Danazol linked to ovarian cancer. The Lancet. Oncology 20020501
A phase 3, multicenter, open label, randomized study of abarelix versus leuprolide plus daily antiandrogen in men with prostate cancer. The Journal of urology 20020401
Hormone therapy in men and risk of cardiac allograft rejection. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020401
Adrenal progestogen and androgen production in 21-hydroxylase-deficient nonclassic adrenal hyperplasia is partially independent of adrenocorticotropic hormone stimulation. Fertility and sterility 20020401
Postparacentesis bilateral massive vulvar edema in a patient with severe ovarian hyperstimulation syndrome. Fertility and sterility 20020401
Antihormonal treatment of paraphilic patients in German forensic psychiatric clinics. European psychiatry : the journal of the Association of European Psychiatrists 20020401
Early menarche and subclinical ovarian hyperandrogenism in girls with reduced adult height after low birth weight. Journal of pediatric endocrinology & metabolism : JPEM 20020401
In vitro characterization and in vivo testosterone suppression of 6-month release poly(D,L-lactide) leuprolide microspheres. Pharmaceutical research 20020401
Successful elective single blastocyst transfer in a patient with prior repetitive high-order multiple gestations. Journal of assisted reproduction and genetics 20020401
Liquid chromatography-mass spectrometry and capillary electrophoresis combined approach for separation and characterization of multicomponent peptide mixtures. Application to crude products of leuprolide synthesis. Journal of chromatography. A 20020315
Pre-treatment nomogram for biochemical control after neoadjuvant androgen deprivation and radical radiotherapy for clinically localised prostate cancer. British journal of cancer 20020304
Leuteinizing hormone responses to leuprolide acetate discriminate between hypogonadotropic hypogonadism and constitutional delay of puberty. Fertility and sterility 20020301
Treatment of central precocious puberty. Best practice & research. Clinical endocrinology & metabolism 20020301
Expression of insulin-like growth factor (IGF), IGF receptor, and IGF-binding protein messenger ribonucleic acids in luteinized granulosa cells from different size follicles after controlled ovarian hyperstimulation. Journal of assisted reproduction and genetics 20020301
Shrinkage effect of gonadotropin releasing hormone agonist treatment on uterine leiomyomas and t(12;14). International journal of oncology 20020201
Serum luteinizing hormone rises within minutes after depot leuprolide injection: implications for monitoring therapy. Pediatrics 20020201
Longitudinal follow-up of bone density and body composition in children with precocious or early puberty before, during and after cessation of GnRH agonist therapy. The Journal of clinical endocrinology and metabolism 20020201
Changes in body composition during androgen deprivation therapy for prostate cancer. The Journal of clinical endocrinology and metabolism 20020201
Endocrine profiles after triggering of final oocyte maturation with GnRH agonist after cotreatment with the GnRH antagonist ganirelix during ovarian hyperstimulation for in vitro fertilization. The Journal of clinical endocrinology and metabolism 20020201
Normalization of serum testosterone levels in patients treated with neoadjuvant hormonal therapy and three-dimensional conformal radiotherapy for prostate cancer. International journal of radiation oncology, biology, physics 20020201
Role of hormonal therapy in the management of intermediate- to high-risk prostate cancer treated with permanent radioactive seed implantation. International journal of radiation oncology, biology, physics 20020201
Chemotherapy versus hormonal treatment in platinum- and paclitaxel-refractory ovarian cancer: a randomised trial of the German Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) Study Group Ovarian Cancer. Annals of oncology : official journal of the European Society for Medical Oncology 20020201
Effects of gonadotropin-releasing hormone analog treatment on skin condition. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20020201
Use of gonadotrophin-releasing hormone agonists to trigger ovulation. Human fertility (Cambridge, England) 20020201
The gonadotrophin-releasing hormone antagonist ganirelix--history and introductory data. Human fertility (Cambridge, England) 20020201
Relationship between platelet-derived growth factor expression in leiomyomas and uterine volume changes after gonadotropin-releasing hormone agonist treatment. Human pathology 20020201
Neoadjuvant androgen ablation before radical prostatectomy in cT2bNxMo prostate cancer: 5-year results. The Journal of urology 20020101
Effects of treatment with GH alone or in combination with LHRH analog on bone mineral density in pubertal GH-deficient patients. The Journal of clinical endocrinology and metabolism 20020101
Cessation of low-dose gonadotropin releasing hormone agonist therapy followed by high-dose gonadotropin stimulation yields a favorable ovarian response in poor responders. Journal of assisted reproduction and genetics 20020101
Comparative study of pressure-flow parameters. Neurourology and urodynamics 20020101
Case report: the management of bone demineralization associated with long-term treatment of multiple paraphilias with long-acting LHRH agonists. Journal of sex & marital therapy 20020101
Add-backs to prevent skeletal fragility: foresight or folly? Menopause (New York, N.Y.) 20020101
Prevention of bone loss and hypoestrogenic symptoms by estrogen and interrupted progestogen add-back in long-term GnRH-agonist down-regulated patients with endometriosis and premenstrual syndrome. Menopause (New York, N.Y.) 20020101
Clinical pharmacokinetics of depot leuprorelin. Clinical pharmacokinetics 20020101
Intravenous leiomyomatosis of the uterus. Anticancer research 20020101
Cyclophosphamide, methotrexate and fluorouracil (CMF) versus hormonal ablation with leuprorelin acetate as adjuvant treatment of node-positive, premenopausal breast cancer patients: preliminary results of the TABLE-study (Takeda Adjuvant Breast cancer study with Leuprorelin Acetate). Anticancer research 20020101
Effects of GnRH agonist (leuprolide) on reproduction and behaviour in female wapiti (Cervus elaphus nelsoni). Reproduction (Cambridge, England) Supplement 20020101
Coping and health-related quality of life in men with prostate cancer randomly assigned to hormonal medication or close monitoring. Psycho-oncology 20020101
Pituitary haemorrhage after leuprolide therapy for prostatic cancer, clinically imitating acute subarachnoidal haemorrhage. Cerebrovascular diseases (Basel, Switzerland) 20020101
Impact of metformin therapy on ovarian stimulation and outcome in 'coasted' patients with polycystic ovary syndrome undergoing in-vitro fertilization. Reproductive biomedicine online 20020101
Long-term suppression of pituitary-gonadal function with three-month depot of leuprorelin acetate in a girl with central precocious puberty. Hormone research 20020101
Multimodality radiotherapy and androgen ablation in the treatment of clinically localized prostate cancer: early results in high risk patients. Prostate cancer and prostatic diseases 20020101
Depot leuprorelin acetate versus danazol in the treatment of infertile women with symptomatic endometriosis. European journal of gynaecological oncology 20020101
Serum estradiol levels after 4 days of ovarian hyperstimulation in oocyte donors are predictive of embryo quality and clinical outcomes. Gynecologic and obstetric investigation 20020101
Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss. Prostate cancer and prostatic diseases 20020101
Preliminary toxicity and prostate-specific antigen response of a Phase I/II trial of neoadjuvant hormonal therapy, 103Pd brachytherapy, and three-dimensional conformal external beam irradiation in the treatment of locally advanced prostate cancer. Brachytherapy 20020101
Modification of the spinal peak growth velocity as a possible treatment for adult scoliosis. Studies in health technology and informatics 20020101
Human ovarian steroid secretion in vivo: effects of GnRH agonist versus antagonist (cetrorelix). Human reproduction (Oxford, England) 20011201
Polycystic ovaries in Hirsute women with normal menses. The American journal of medicine 20011201
'Co-Flare' stimulation in the poor responder patient: predictive value of the flare response. Journal of assisted reproduction and genetics 20011201
Managing advanced prostate cancer with Viadur (leuprolide acetate implant). Urologic nursing 20011201
Pharmaceutical company to pay $875 million to settle federal case. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20011115
Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer--a preliminary report. International journal of radiation oncology, biology, physics 20011101
Late intracaval and intracardiac leiomyomatosis following hysterectomy for benign myomas treated by surgery and GnRH agonist. Gynecologic oncology 20011101
Post-operative GnRH analogue treatment after conservative surgery for symptomatic endometriosis stage III-IV: a randomized controlled trial. Human reproduction (Oxford, England) 20011101
Localized prostate cancer: effect of hormone deprivation therapy measured by using combined three-dimensional 1H MR spectroscopy and MR imaging: clinicopathologic case-controlled study. Radiology 20011101
Reversal of gonadotropin-releasing hormone agonist induced reductions in mammographic densities on stopping treatment. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20011101
Inhibition of in situ expression of aromatase P450 in leiomyoma of the uterus by leuprorelin acetate. The Journal of clinical endocrinology and metabolism 20011101
Pulsatile iv infusion of recombinant human LH in leuprolide-suppressed men unmasks impoverished Leydig-cell secretory responsiveness to midphysiological LH drive in the aging male. The Journal of clinical endocrinology and metabolism 20011101
A phase 3, multicenter, open-label, randomized study of abarelix versus leuprolide acetate in men with prostate cancer. Urology 20011101
[Clinical efficacy of leuprolide acetate and combined treatment with estramustine for advanced prostate cancer]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20011101
Pulmonary peptide delivery: effect of taste-masking excipients on leuprolide suspension metered-dose inhalers. Pharmaceutical development and technology 20011101
Prospective randomized comparison of ovarian blockade with nafarelin versus leuprolide during ovarian stimulation with recombinant FSH in an ICSI program. Journal of assisted reproduction and genetics 20011101
GnRH analog, leuprorelin acetate, promotes regeneration of rat spermatogenesis after severe chemical damage. International journal of urology : official journal of the Japanese Urological Association 20011101
Record settlement on TAP. Drugmaker pleads guilty to criminal violations. Modern healthcare 20011008
Gonadotropin-releasing hormone agonist affects rat ovarian follicle development by interfering with FSH and growth factors on the prevention of apoptosis. Molecular reproduction and development 20011001
Estrogen and progesterone effects on transcapillary fluid dynamics. American journal of physiology. Regulatory, integrative and comparative physiology 20011001
Randomized double-blind study evaluating the efficacy on uterine fibroids shrinkage and on intra-operative blood loss of different length of leuprolide acetate depot treatment before myomectomy. Acta obstetricia et gynecologica Scandinavica 20011001
The effect of pubertal delay by GnRH agonist in GH-deficient children on final height. The Journal of clinical endocrinology and metabolism 20011001
Confounders? Fertility and sterility 20011001
Estrogens and bone health in men. Calcified tissue international 20011001
Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer. The New England journal of medicine 20010927
Bone loss accompanying medical therapies. The New England journal of medicine 20010927
Metachromasia of the endocervical epithelium in women treated with gonadotropin releasing hormone agonist. International journal of molecular medicine 20010901
Quality-of-life outcomes after primary androgen deprivation therapy: results from the Prostate Cancer Outcomes Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010901
Patient-reported experience with the Viadur 12-month leuprolide implant for prostate cancer. Urology 20010901
'You'll know it when you see it' statistics. Fertility and sterility 20010901
'You'll know it when you see it' statistics. Fertility and sterility 20010901
Preparation, characterization and in vivo evaluation of 120-day poly(D,L-lactide) leuprolide microspheres. Journal of controlled release : official journal of the Controlled Release Society 20010810
Effects of gonadal steroids on peripheral benzodiazepine receptor density in women with PMS and controls. Psychoneuroendocrinology 20010801
Depot-leuprolide acetate for treatment of paraphilias: a report of twelve cases. Archives of sexual behavior 20010801
Randomized comparative study of 3 versus 8-month neoadjuvant hormonal therapy before radical prostatectomy: biochemical and pathological effects. The Journal of urology 20010801
Response of hormone refractory prostate cancer to lycopene. The Journal of urology 20010801
Longstanding survival without cancer progression in a patient affected by endometrial carcinoma treated primarily with leuprolide. British journal of cancer 20010801
Intermittent androgen deprivation: update of cycling characteristics in patients without clinically apparent metastatic prostate cancer. Urology 20010801
Luteinizing hormone-releasing hormone antagonists in prostate cancer. Urology 20010801
TNF-alpha and hyperandrogenism: a clinical, biochemical, and molecular genetic study. The Journal of clinical endocrinology and metabolism 20010801
[Intermittent androgen deprivation treatment of prostate cancer restarted at low level of serum prostate specific antigen: a pilot study]. Hinyokika kiyo. Acta urologica Japonica 20010801
Docetaxel followed by hormone therapy after failure of definitive treatments for clinically localized/locally advanced prostate cancer: preliminary results. Seminars in oncology 20010801
An in vivo/in vitro comparison with a leuprolide osmotic implant for the treatment of prostate cancer. Journal of controlled release : official journal of the Controlled Release Society 20010710
Lupron depot prevention of antispermatogenic/antifertility activity of the indenopyridine, CDB-4022, in the rat. Biology of reproduction 20010701
Fresh embryo transfer is more effective than frozen for donor oocyte recipients but not for donors. Human reproduction (Oxford, England) 20010701
Gonadotropin-releasing hormone agonist failure in a man with prostate cancer. The Journal of urology 20010701
Soluble ICAM-1 levels in the serum of endometriotic patients appear to be independent of medical treatment. Journal of reproductive immunology 20010701
Efficacy of ipriflavone in preventing adverse effects of leuprolide. The Journal of clinical endocrinology and metabolism 20010701
Leuprolide - as needed. Fertility and sterility 20010701
Why phase III trials of maximal androgen blockade versus castration in M1 prostate cancer rarely show statistically significant differences. The Prostate 20010615
Association of the shrinkage of uterine leiomyoma treated with GnRH agonist and deletion of long arm of chromosome 7. International journal of oncology 20010601
Use of GnRH analogs for functional protection of the ovary and preservation of fertility during cancer treatment in adolescents: a preliminary report. Gynecologic oncology 20010601
Prospective randomized study comparing the GnRH-agonist leuprorelin acetate and the gestagen lynestrenol in the treatment of severe endometriosis. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20010601
Leuprorelin and triptorelin: new indication. Preoperative treatment of uterine leiomyoma: no proven value. Prescrire international 20010601
Endothelin-1 in human prostatic carcinoma treated with androgen withdrawal: an immunohistochemical study. Cancer 20010515
Direct effects of GnRH agonists in human hormone-sensitive endometrial cells. Molecular and cellular endocrinology 20010515
Chemical andropause and amyloid-beta peptide. JAMA 20010502
Comparison of agonistic flare-up-protocol and antagonistic multiple dose protocol in ovarian stimulation of poor responders: results of a prospective randomized trial. Human reproduction (Oxford, England) 20010501
Prostate-specific antigen-all that rises is not refractory. Urology 20010501
The gonadotropin-releasing hormone antagonist abarelix depot versus luteinizing hormone releasing hormone agonists leuprolide or goserelin: initial results of endocrinological and biochemical efficacies in patients with prostate cancer. The Journal of urology 20010501
Clinical pregnancy rates in an IVF program. Use of the flare-up protocol after failure with long regimens of GnRH-a. The Journal of reproductive medicine 20010501
A case of pulmonary endometriosis--a rare case report and a successful treatment experience. The Kaohsiung journal of medical sciences 20010501
Leuprolide acetate treatment of adrenocortical disease in ferrets. Journal of the American Veterinary Medical Association 20010415
Continuously proliferative stem germ cells partially repopulate the aged, atrophic rat testis after gonadotropin-releasing hormone agonist therapy. Biology of reproduction 20010401
Secretory leukocyte protease inhibitor in ovarian endometriomas following GnRH agonist therapy. Obstetrics and gynecology 20010401
Primary medical management of recurrent aggressive angiomyxoma of the vulva with a gonadotropin-releasing hormone agonist. Gynecologic oncology 20010401
Serum and follicular fluid hormone levels during in vitro fertilization after short- or long-course treatment with a gonadotropin-releasing hormone agonist. Fertility and sterility 20010401
The effect of early postnatal treatment with a gonadotropin-releasing hormone agonist on the developmental profiles of testicular steroid hormones in the intact male pig. Journal of animal science 20010401
Expression of the gap junction connexins Cx43, Cx45 and Cx26 in human uterine leiomyomata. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20010401
Effect of the GnRH-agonist leuprolide on colonization of recipient testes by donor spermatogonial stem cells after transplantation in mice. Tissue & cell 20010401
The possible anti-inflammatory role of circulating human leukocyte antigen levels in women with endometriosis after treatment with danazol and leuprorelin acetate depot. Mediators of inflammation 20010401
Lipid extraction and iontophoretic transport of leuprolide acetate through porcine epidermis. International journal of pharmaceutics 20010314
Body fat distribution and body composition during GnRH agonist therapy. Obstetrics and gynecology 20010301
Sex hormone dependency of diethylnitrosamine-induced liver tumors in mice and chemoprevention by leuprorelin. Japanese journal of cancer research : Gann 20010301
Medical and surgical therapies for pain associated with endometriosis. Journal of women's health & gender-based medicine 20010301
Effects of the luteinising hormone-releasing hormone (LH-RH) agonist leuprolide on adenylyl cyclase regulation through G-protein coupled receptors in rat ventral prostate. European journal of cancer (Oxford, England : 1990) 20010301
Effects of gonadal steroid suppression on skeletal sensitivity to parathyroid hormone in men. The Journal of clinical endocrinology and metabolism 20010201
Effects of leuprolide acetate on adhesion formation and wound healing in the rat model. The Journal of the American Association of Gynecologic Laparoscopists 20010201
Use of leuprolide acetate plus tibolone in the treatment of severe premenstrual syndrome. Fertility and sterility 20010201
Effectiveness of short-term administration of tibolone plus gonadotropin-releasing hormone analogue on the surgical outcome of laparoscopic myomectomy. Fertility and sterility 20010201
[Comparison of different protocols of ovulation induction, by GnRH agonists and chorionic gonadotropin]. Gynecologie, obstetrique & fertilite 20010201
Determination of the efficiency of controlled ovarian hyperstimulation in the gonadotropin-releasing hormone agonist-suppression cycle using the initial follicle count during gonadotropin stimulation. Journal of assisted reproduction and genetics 20010201
[Prognostic value assessment of the early response of blood estradiol, FSH, and LH using leuprolide acetate during ovarian hyperstimulation in assisted reproduction]. Ginecologia y obstetricia de Mexico 20010201
[Anemia and neoadjuvant hormone therapy in radical surgery of localized cancer of the prostate]. Actas urologicas espanolas 20010201
Inhibition of PSA flare in prostate cancer patients by administration of flutamide for 2 weeks before initiation of treatment with slow-releasing LH-RH agonist. International journal of clinical oncology 20010201
Medical versus surgical androgen suppression therapy for prostate cancer: a 10-year longitudinal cost study. The Journal of urology 20010101
Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation. Fertility and sterility 20010101
Oestrogen deficiency causes DNA damage in uterine leiomyoma cells: a possible mechanism for shrinkage of fibroids by GnRH agonists. BJOG : an international journal of obstetrics and gynaecology 20010101
Treatment of paraphilia with luteinizing hormone-releasing hormone agonists. Journal of sex & marital therapy 20010101
[Suppressive effects of the antiandrogen flutamide on adrenal androgens in advanced prostate cancer patients]. Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20010101
[Novel intermittent GnRHa therapy for patients with endometriosis]. Nihon rinsho. Japanese journal of clinical medicine 20010101
Pregnancy and birth after GnRH agonist treatment for induction of final oocyte maturation in a woman undergoing ovarian stimulation for ICSI, using a GnRH antagonist (Orgalutran/Antagon) to prevent a premature LH surge: a case report. Journal of assisted reproduction and genetics 20010101
Treatment of localized prostate cancer with intermittent triple androgen blockade: preliminary results in 110 consecutive patients. The oncologist 20010101
Optimal starting time for flutamide to prevent disease flare in prostate cancer patients treated with a gonadotropin-releasing hormone agonist. Urologia internationalis 20010101
Effects of herbal medicines on menopausal symptoms induced by gonadotropin-releasing hormone agonist therapy. Clinical and experimental obstetrics & gynecology 20010101
Fibromyalgia developed after administration of gonadotrophin-releasing hormone analogue. Clinical rheumatology 20010101
Presence of LH in gonadotropins associated with higher IVF pregnancy rates when basal serum LH is increased. Clinical and experimental obstetrics & gynecology 20010101
GnRH agonists and antagonists stimulate recovery of fertility in irradiated LBNF1 rats. Journal of andrology 20010101
Recovery of serum testosterone, LH and FSH levels following neoadjuvant hormone cytoreduction and radical radiotherapy in localized prostate cancer. Clinical oncology (Royal College of Radiologists (Great Britain)) 20010101
Effect of gonadotropin-releasing hormone agonist treatment upon angiogenesis in uterine leiomyoma. Gynecologic and obstetric investigation 20010101
Prevention of menstruation with leuprorelin (GnRH agonist) in women undergoing myelosuppressive chemotherapy or radiochemotherapy for hematological malignancies: a pilot study. Leukemia & lymphoma 20010101
Efficacy of every-other-day administration of conjugated equine estrogen and medroxyprogesterone acetate on gonadotropin-releasing hormone agonists treatment in women with endometriosis. Gynecologic and obstetric investigation 20010101
Suppression of spermatogenesis for cell transplantation in adult mice. Protoplasma 20010101
Spermatogenesis by Sisyphus: proliferating stem germ cells fail to repopulate the testis after 'irreversible' injury. Advances in experimental medicine and biology 20010101
Chronic (60-week) toxicity study of DUROS leuprolide implants in dogs. International journal of toxicology 20010101
A case of atypical absence seizures induced by leuprolide acetate. Pediatric neurology 20000901
Uterine adenocarcinoma after GnRH agonist treatment. Archives of gynecology and obstetrics 20000201
Lead and Aroclor 1254 disrupt reproductive neuroendocrine function in Atlantic croaker. Marine environmental research 20000101
[Seizure exacerbation by the use of leuprorelin acetate for treatment of central precocious puberty in a female patient with symptomatic localization-related epilepsy]. No to hattatsu = Brain and development 19990901
[Primary treatment for stage D2 prostate cancer: a randomized study of combined androgen blockade alone versus combined with UFT]. Gan to kagaku ryoho. Cancer & chemotherapy 19990701
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