4,4'-(1-Triazene-1,3-diyl)bis[benzenecarboximidamide]
Title | Journal |
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Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms. | Arteriosclerosis, thrombosis, and vascular biology 20141201 |
Is trypanocidal drug resistance a threat for livestock health and production in endemic areas? Food for thoughts from Sahelian goats infected by Trypanosoma vivax in Bobo Dioulasso (Burkina Faso). | Veterinary parasitology 20121221 |
Comparative serum biochemical changes induced by experimental infection of T. brucei and T. congolense in pigs. | Veterinary parasitology 20121221 |
Ghibe river basin in Ethiopia: present situation of trypanocidal drug resistance in Trypanosoma congolense using tests in mice and PCR-RFLP. | Veterinary parasitology 20121026 |
Involvement of mitochondrial genes of Babesia gibsoni in resistance to diminazene aceturate. | The Journal of veterinary medical science 20120901 |
Purification of plasmid DNA from clarified and non-clarified Escherichia coli lysates by berenil pseudo-affinity chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901 |
Analysis of energy generation and glycolysis pathway in diminazene aceturate-resistant Babesia gibsoni isolate in vitro. | The Japanese journal of veterinary research 20120801 |
Field detection of resistance to isometamidium chloride and diminazene aceturate in Trypanosoma vivax from the region of the Boucle du Mouhoun in Burkina Faso. | Veterinary parasitology 20120608 |
The therapeutic efficacy of two antibabesial strategies against Babesia gibsoni. | Veterinary parasitology 20120525 |
Modeling the control of trypanosomiasis using trypanocides or insecticide-treated livestock. | PLoS neglected tropical diseases 20120501 |
Development of in vitro atovaquone-resistant Babesia gibsoni with a single-nucleotide polymorphism in cytb. | Veterinary parasitology 20120430 |
Energetics of ligand binding to the DNA minor groove. | Physical chemistry chemical physics : PCCP 20120428 |
Current advances in detection and treatment of babesiosis. | Current medicinal chemistry 20120401 |
Quinol derivatives as potential trypanocidal agents. | Bioorganic & medicinal chemistry 20120215 |
Diamidinium and iminium aromatics as new aggregators of the bacterial signaling molecule, c-di-GMP. | Bioorganic & medicinal chemistry letters 20120115 |
Highly debilitating natural Trypanosoma vivax infections in Brazilian calves: epidemiology, pathology, and probable transplacental transmission. | Parasitology research 20120101 |
Comparison of protective immune responses to apicomplexan parasites. | Journal of parasitology research 20120101 |
Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. | Journal of drug delivery 20120101 |
Validation of an HPLC method for the simultaneous determination of diminazene diaceturate and phenazone in injectable veterinary granules and bulk powders. | Pakistan journal of pharmaceutical sciences 20120101 |
The Trypanosoma cruzi virulence factor oligopeptidase B (OPBTc) assembles into an active and stable dimer. | PloS one 20120101 |
How full is our antihypertensives pipeline? | Journal of pharmacology & pharmacotherapeutics 20120101 |
Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali. | Parasites & vectors 20120101 |
Biological activities of xanthatin from Xanthium strumarium leaves. | Phytotherapy research : PTR 20111201 |
Biodynamic parameters of micellar diminazene in sheep erythrocytes and blood plasma. | Journal of veterinary science 20111201 |
High prevalence of drug resistance in animal trypanosomes without a history of drug exposure. | PLoS neglected tropical diseases 20111201 |
Susceptibility of mice to Trypanosoma evansi treated with human plasma containing different concentrations of apolipoprotein L-1. | The Korean journal of parasitology 20111201 |
Convolutamines I and J, antitrypanosomal alkaloids from the bryozoan Amathia tortusa. | Bioorganic & medicinal chemistry 20111115 |
The pharmacological profile of brain liver intestine Na+ channel: inhibition by diarylamidines and activation by fenamates. | Molecular pharmacology 20111101 |
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke. | Experimental physiology 20111001 |
Managing tsetse transmitted trypanosomosis by insecticide treated nets--an affordable and sustainable method for resource poor pig farmers in Ghana. | PLoS neglected tropical diseases 20111001 |
Genital lesions in male red fronted gazelles (Gazella rufifrons) experimentally infected with Trypanosoma brucei and the effect of melarsamine hydrochloride (Cymelarsan®) and diminazene aceturate (Berenil®) in its treatment. | Theriogenology 20110901 |
CBFB and MYH11 in inv(16)(p13q22) of acute myeloid leukemia displaying close spatial proximity in interphase nuclei of human hematopoietic stem cells. | Genes, chromosomes & cancer 20110901 |
Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities. | The Biochemical journal 20110901 |
Prediction of off-target effects on angiotensin-converting enzyme 2. | Journal of biomolecular screening 20110901 |
Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis. | PLoS neglected tropical diseases 20110901 |
Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi. | Journal of the South African Veterinary Association 20110901 |
Experimental infection with Rangelia vitalii in dogs: acute phase, parasitemia, biological cycle, clinical-pathological aspects and treatment. | Experimental parasitology 20110801 |
Polyamines in aging and disease. | Aging 20110801 |
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense. | Acta tropica 20110701 |
Diminazene aceturate associated with sodium selenite and vitamin E in the treatment of Trypanosoma evansi infection in rats. | Experimental parasitology 20110701 |
The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes. | Molecular pharmacology 20110701 |
Improved PCR-RFLP for the detection of diminazene resistance in Trypanosoma congolense under field conditions using filter papers for sample storage. | PLoS neglected tropical diseases 20110701 |
Drug delivery systems in the treatment of African trypanosomiasis infections. | Expert opinion on drug delivery 20110601 |
SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis. | PLoS neglected tropical diseases 20110601 |
Specific berenil-DNA interactions: an approach for separation of plasmid isoforms by pseudo-affinity chromatography. | Analytical biochemistry 20110515 |
Effect of topoisomerase inhibitors and DNA-binding drugs on the cell proliferation and ultrastructure of Trypanosoma cruzi. | International journal of antimicrobial agents 20110501 |
The effects of combination of methanolic leaf extract of Azadirachta indica and diminazene diaceturate in the treatment of experimental Trypanosoma brucei brucei infection in rats. | Asian Pacific journal of tropical medicine 20110501 |
Horses naturally infected by Trypanosoma vivax in southern Brazil. | Parasitology research 20110101 |
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation. | Bioorganic & medicinal chemistry 20110101 |
Emergence of new types of Theileria orientalis in Australian cattle and possible cause of theileriosis outbreaks. | Parasites & vectors 20110101 |
Efficacy study of novel diamidine compounds in a Trypanosoma evansi goat model. | PloS one 20110101 |
Molecular and cellular characterization of an AT-hook protein from Leishmania. | PloS one 20110101 |
In vitro and in vivo antileishmanial efficacy of a combination therapy of diminazene and artesunate against Leishmania donovani in BALB/c mice. | Revista do Instituto de Medicina Tropical de Sao Paulo 20110101 |
Functional modifications of acid-sensing ion channels by ligand-gated chloride channels. | PloS one 20110101 |
Neglected disease - african sleeping sickness: recent synthetic and modeling advances. | Scientia pharmaceutica 20110101 |
Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones. | Molecular biology international 20110101 |
Gold nanoparticles in biology and medicine: recent advances and prospects. | Acta naturae 20110101 |
Development of a nanoparticulate formulation of diminazene to treat African trypanosomiasis. | Nanotechnology 20101217 |
Crystal structure of Leishmania major oligopeptidase B gives insight into the enzymatic properties of a trypanosomatid virulence factor. | The Journal of biological chemistry 20101210 |
The killing of African trypanosomes by ethidium bromide. | PLoS pathogens 20101201 |
Reduced transcript levels of the heat shock protein 70 gene in diminazene aceturate-resistant Babesia gibsoni variants under low concentrations of diminazene aceturate. | The Japanese journal of veterinary research 20101101 |
Babesia canis and Babesia rossi co-infection in an untraveled Nigerian dog. | Veterinary parasitology 20101029 |
Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin. | PLoS neglected tropical diseases 20100901 |
Efficacy of Cymelarsan and Diminasan against Trypanosoma equiperdum infections in mice and horses. | Veterinary parasitology 20100804 |
Malaria gametocytogenesis. | Molecular and biochemical parasitology 20100801 |
Selective delivery of 2-hydroxy APA to Trypanosoma brucei using the melamine motif. | Bioorganic & medicinal chemistry letters 20100801 |
Trypanosoma vivax infections: pushing ahead with mouse models for the study of Nagana. I. Parasitological, hematological and pathological parameters. | PLoS neglected tropical diseases 20100801 |
DNA instability at chromosomal fragile sites in cancer. | Current genomics 20100801 |
Diarylamidines: high potency inhibitors of acid-sensing ion channels. | Neuropharmacology 20100601 |
Development and characterization of a strain of Babesia gibsoni resistant to diminazene aceturate in vitro. | The Journal of veterinary medical science 20100601 |
Structural binding evidence of the trypanocidal drugs berenil and pentacarinate active principles to a serine protease model. | International journal of biological macromolecules 20100601 |
In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi. | Veterinary parasitology 20100511 |
Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species. | European journal of medicinal chemistry 20100301 |
Frequency and therapy monitoring of canine Babesia spp. infection by high-resolution melting curve quantitative FRET-PCR. | Veterinary parasitology 20100226 |
Antitrypanosomal activity of 1,2-dihydroquinolin-6-ols and their ester derivatives. | Journal of medicinal chemistry 20100211 |
Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes. | Eukaryotic cell 20100201 |
Evaluation of the in vitro growth-inhibitory effect of epoxomicin on Babesia parasites. | Veterinary parasitology 20100120 |
Characterization of major surface protease homologues of Trypanosoma congolense. | Journal of biomedicine & biotechnology 20100101 |
Immunobiology of African trypanosomes: need of alternative interventions. | Journal of biomedicine & biotechnology 20100101 |
Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging. | Particle and fibre toxicology 20100101 |
Proteomics of Trypanosoma evansi infection in rodents. | PloS one 20100101 |
Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni. | Acta veterinaria Scandinavica 20100101 |
Distamycin A inhibits HMGA1-binding to the P-selectin promoter and attenuates lung and liver inflammation during murine endotoxemia. | PloS one 20100101 |
Experiences with an in-training community service model in the control of zoonotic sleeping sickness in Uganda. | Journal of veterinary medical education 20100101 |
The effect of a novel dinuclear platinum complex with berenil and 2-picoline ligands on growth of human breast cancer cells. | Acta poloniae pharmaceutica 20100101 |
Senna occidentalis leaf extract possesses antitrypanosomal activity and ameliorates the trypanosome-induced anemia and organ damage. | Pharmacognosy research 20100101 |
The intravenous pharmacokinetics of diminazene in healthy dogs. | Journal of the South African Veterinary Association 20091201 |
The effects of hairpin loops on ligand-DNA interactions. | The journal of physical chemistry. B 20091029 |
Diminazene aceturate in the control of Trypanosoma evansi infection in cats. | Veterinary parasitology 20091028 |
Structure and inhibition of human diamine oxidase. | Biochemistry 20091020 |
Endemic type of animal trypanosomiasis is not associated with lower genotype variability of Trypanosoma congolense isolates circulating in livestock. | Research in veterinary science 20091001 |
Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. | The American journal of tropical medicine and hygiene 20091001 |
Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal. | PLoS neglected tropical diseases 20090901 |
Advancing drug innovation for neglected diseases-criteria for lead progression. | PLoS neglected tropical diseases 20090801 |
Effects of melarsamine hydrochloride (Cymelarsan) and diminazene aceturate (Berenil) on the pathology of experimental Trypanosoma brucei infection in red fronted gazelles (Gazella rufifrons). | Veterinary parasitology 20090707 |
Immunospecific immunoglobulins and IL-10 as markers for Trypanosoma brucei rhodesiense late stage disease in experimentally infected vervet monkeys. | Tropical medicine & international health : TM & IH 20090701 |
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. | Brain : a journal of neurology 20090501 |
Isolation of antibabesial compounds from Brucea javanica, Curcuma xanthorrhiza, and Excoecaria cochinchinensis. | Bioscience, biotechnology, and biochemistry 20090323 |
Evaluation of efficacy of bruceine A, a natural quassinoid compound extracted from a medicinal plant, Brucea javanica, for canine babesiosis. | The Journal of veterinary medical science 20090101 |
Canine babesiosis: from molecular taxonomy to control. | Parasites & vectors 20090101 |
Chemotherapy of human african trypanosomiasis. | Interdisciplinary perspectives on infectious diseases 20090101 |
A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427. | Parasites & vectors 20090101 |
In vitro antitrypanosomal activities of quassinoid compounds from the fruits of a medicinal plant, Brucea javanica. | Veterinary parasitology 20081220 |
Pharmacophore based discovery of potential antimalarial agent targeting haem detoxification pathway. | European journal of medicinal chemistry 20081201 |
Five-fold increase in Trypanosoma congolense isolates resistant to diminazene aceturate over a seven-year period in Eastern Zambia. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20081201 |
The blood-brain barrier significantly limits eflornithine entry into Trypanosoma brucei brucei infected mouse brain. | Journal of neurochemistry 20081101 |
Preparation of polyclonal antibodies to diminazene and its detection in animal blood plasma. | International immunopharmacology 20081001 |
The promotion of secondary structures in single-stranded DNA by drugs that bind to duplex DNA: an atomic force microscopy study. | Nanotechnology 20080924 |
Estimation of tsetse challenge and its relationship with trypanosomosis incidence in cattle kept under pastoral production systems in Kenya. | Veterinary parasitology 20080817 |
Comparative efficacy of diminazene diaceturate and diminazene aceturate for the treatment of babesiosis in horses. | Tropical animal health and production 20080801 |
Enhancement of hydrophilic drug loading and release characteristics through micellization with new carboxymethyldextran-PEG block copolymers of tunable charge density. | International journal of pharmaceutics 20080522 |
Assessment of the occurrence of trypanocidal drug resistance in trypanosomes of naturally infected cattle in the Adamaoua region of Cameroon using the standard mouse test and molecular tools. | Acta tropica 20080501 |
Molecular tools for the rapid detection of drug resistance in animal trypanosomes. | Trends in parasitology 20080501 |
Prevalence of bovine trypanosomosis and trypanocidal drug sensitivity studies on Trypanosoma congolense in Wolyta and Dawero zones of southern Ethiopia. | Veterinary parasitology 20080325 |
Comparative efficacy assessment of pentamidine isethionate and diminazene aceturate in the chemotherapy of Trypanosoma brucei brucei infection in dogs. | Veterinary parasitology 20080214 |
Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB. | Journal of medicinal chemistry 20080214 |
Acute phase response in mice experimentally infected with Trypanosoma congolense: a molecular gauge of parasite-host interaction. | Veterinary parasitology 20080125 |
Microarray analysis of the in vivo sequence preferences of a minor groove binding drug. | BMC genomics 20080101 |
DNA-binding activity and cytotoxicity of Pt-berenil compounds in MDA-MB-231 and MCF-7 breast cancer cells. | Acta poloniae pharmaceutica 20080101 |
Synthesis, DNA-binding affinity and cytotoxicity of the dinuclear platinum(II) complexes with berenil and amines ligands. | Acta poloniae pharmaceutica 20080101 |
A systematic approach to understand the mechanism of action of the bisthiazolium compound T4 on the human malaria parasite, Plasmodium falciparum. | BMC genomics 20080101 |
Screening of Indonesian medicinal plant extracts for antibabesial activity and isolation of new quassinoids from Brucea javanica. | Journal of natural products 20071001 |
Heterogeneity in the trypanosomosis incidence in Zebu cattle of different ages and sex on the plateau of eastern Zambia. | Acta tropica 20070801 |
Clinical management of babesiosis in dogs with homeopathic Crotalus horridus 200C. | Homeopathy : the journal of the Faculty of Homeopathy 20070401 |
Anti-babesial compounds from Curcuma xanthorrhiza. | Natural product research 20070401 |
Molecular characterisation of Babesia gibsoni infection from a pit-bull terrier pup recently imported into South Africa. | Journal of the South African Veterinary Association 20070301 |
Occurrence of multiple drug resistance in Trypanosoma brucei rhodesiense isolated from sleeping sickness patients. | The Onderstepoort journal of veterinary research 20070301 |
The pathogenesis of anaemia in goats experimentally infected with Trypanosoma congolense or Trypanosoma brucei: use of the myeloid:erythroid ratio. | Veterinary parasitology 20070227 |
Rigid dipeptide mimics: synthesis of enantiopure C6-functionalized pyrrolizidinone amino acids. | The Journal of organic chemistry 20070202 |
Trypanosomiasis by Trypanosoma vivax in cattle in the Brazilian semiarid: Description of an outbreak and lesions in the nervous system. | Veterinary parasitology 20070131 |
Co-administration of Na-EDTA and diminazene aceturate (DA) to mice infected with DA-resistant Trypanosoma brucei. | Journal of comparative pathology 20070101 |
Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate. | Acta tropica 20070101 |
Combined contribution of TbAT1 and TbMRPA to drug resistance in Trypanosoma brucei. | Molecular and biochemical parasitology 20061201 |
Androgens differentially potentiate mouse intestinal smooth muscle by nongenomic activation of polyamine synthesis and Rho kinase activation. | Endocrinology 20061201 |
Fumagillin, a new P-glycoprotein-interfering agent able to modulate moxidectin efflux in rat hepatocytes. | Journal of veterinary pharmacology and therapeutics 20061201 |
Confirmation of diminazene diaceturate in bovine plasma using electrospray liquid chromatography-mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061121 |
SSCP analysis of the P2 purine transporter TcoAT1 gene of Trypanosoma congolense leads to a simple PCR-RFLP test allowing the rapid identification of diminazene resistant stocks. | Acta tropica 20061101 |
Response of four indigenous cattle breeds to natural tsetse and trypanosomosis challenge in the Ghibe valley of Ethiopia. | Veterinary parasitology 20061010 |
Porcine eperythrozoonosis in China. | Annals of the New York Academy of Sciences 20061001 |
Equine trypanosomosis in the Central River Division of The Gambia: a study of veterinary gate-clinic consultation records. | Preventive veterinary medicine 20060817 |
Stability analysis for double-stranded DNA oligomers and their noncovalent complexes with drugs by laser spray. | Journal of mass spectrometry : JMS 20060801 |
Excitability scores of goats administered ascorbic acid and transported during hot-dry conditions. | Journal of veterinary science 20060601 |
Chemotherapy against babesiosis. | Veterinary parasitology 20060531 |
Epidemiology of Trypanosoma vivax infection in cattle in the tse-tse free area of Lake Chad. | Preventive veterinary medicine 20060517 |
Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection. | Veterinary parasitology 20060430 |
Quantitative analysis of DNA-porphyrin interactions. | Biopolymers 20060405 |
Complexes of poly(ethylene oxide)-block-poly(L-glutamate) and diminazene. | Langmuir : the ACS journal of surfaces and colloids 20060227 |
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania. | Tropical medicine & international health : TM & IH 20060201 |
Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays. | Experimental parasitology 20060101 |
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats. | Parasitology 20060101 |
RNA aptamers as potential pharmaceuticals against infections with African trypanosomes. | Handbook of experimental pharmacology 20060101 |
The effectivity analysis of accumulation of liposomal, micellar, and water-soluble forms of diminazene in cells and in organs. | Drug delivery 20060101 |
In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators. | Kinetoplastid biology and disease 20060101 |
Comparative application of wavelet approaches to absorption and ratio spectra for the simultaneous determination of diminazene aceturate and phenazone in veterinary granules for injection. | Die Pharmazie 20051201 |
The susceptibility of Trypanosoma congolense isolated in Zambézia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride. | The Onderstepoort journal of veterinary research 20051201 |
Acquired resistance to berenil in a cloned isolate of Trypanosoma evansi is associated with upregulation of a novel gene, TeDR40. | Parasitology 20051101 |
Thermodynamic evaluation and modeling of proton and water exchange associated with benzamidine and berenil binding to beta-trypsin. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20051101 |
Diminazene aceturate resistance on the virulence of Trypanosoma brucei for rats. | Journal of comparative pathology 20051101 |
The pharmacokinetics of diminazene aceturate after intramuscular administration in healthy dogs. | Journal of the South African Veterinary Association 20050901 |
Synthesis of a novel PEG-block-poly(aspartic acid-stat-phenylalanine) copolymer shows potential for formation of a micellar drug carrier. | International journal of pharmaceutics 20050613 |
Susceptibility of West African Dwarf goats and WAD x Saanen crosses to experimental infection with Trypanosoma congolense. | Veterinary parasitology 20050610 |
Identification of anti-babesial activity for four ethnoveterinary plants in vitro. | Veterinary parasitology 20050610 |
Anti-babesial compounds from Curcuma zedoaria. | Planta medica 20050501 |
Semicarbazide-functionalized Si(111) surfaces for the site-specific immobilization of peptides. | Langmuir : the ACS journal of surfaces and colloids 20050215 |
Exotic diseases of dogs and cats at risk of importation to Ireland. | Irish veterinary journal 20050101 |
Transition models to assess risk factors for new and persistent trypanosome infections in cattle-analysis of longitudinal data from the Ghibe Valley, southwest Ethiopia. | The Journal of parasitology 20041201 |
Knowledge and attitudes of cattle owners regarding trypanosomosis control in tsetse-infested areas of Uganda. | Journal of the South African Veterinary Association 20041201 |
Analysis of GAA/TTC DNA triplexes using nuclear magnetic resonance and electrospray ionization mass spectrometry. | Analytical biochemistry 20041115 |
Degradation of berenil (diminazene aceturate) in acidic aqueous solution. | The Journal of pharmacy and pharmacology 20041001 |
Trypanocidal failure suggested by PCR results in cattle field samples. | Acta tropica 20040901 |
Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda. | The Onderstepoort journal of veterinary research 20040901 |
DNA minor groove binders as potential antitumor and antimicrobial agents. | Medicinal research reviews 20040701 |
Micronuclei induced by aneugens and clastogens in mononucleate and binucleate cells using the cytokinesis block assay. | Mutagenesis 20040701 |
Effect of diminazene block treatment on live redwater vaccine reactions. | The Onderstepoort journal of veterinary research 20040601 |
Lipid-drug conjugate nanoparticles of the hydrophilic drug diminazene-cytotoxicity testing and mouse serum adsorption. | Journal of controlled release : official journal of the Controlled Release Society 20040518 |
Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage. | The Journal of biological chemistry 20040402 |
Application of field methods to assess isometamidium resistance of trypanosomes in cattle in western Ethiopia. | Acta tropica 20040401 |
Characterization of a novel DNA minor-groove complex. | Biophysical journal 20040201 |
Trypanocidal drug resistance in eastern province of Zambia. | Veterinary parasitology 20040130 |
The effects of diminazene aceturate and ceftriaxone on ram sperm. | Theriogenology 20040115 |
A large-scale trial to evaluate the efficacy of a 1% pour-on formulation of cyfluthrin (Cylence, Bayer) in controlling bovine trypanosomosis in Eastern Zambia. | Tropical animal health and production 20040101 |
RNA-interference silencing of the adenosine transporter-1 gene in Trypanosoma evansi confers resistance to diminazene aceturate. | Experimental parasitology 20040101 |
Gametocytogenesis: the puberty of Plasmodium falciparum. | Malaria journal 20040101 |
Efficacy of combined atovaquone and azithromycin for therapy of chronic Babesia gibsoni (Asian genotype) infections in dogs. | Journal of veterinary internal medicine 20040101 |
Efficacy of Trypan: a diminazene based drug as antileishmanial agent. | Acta tropica 20040101 |
The effect of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes. | Chemico-biological interactions 20031215 |
Changes in adenosine transport associated with melaminophenyl arsenical (Mel CY) resistance in Trypanosoma evansi: down-regulation and affinity changes of the P2 transporter. | Parasitology 20031201 |
The leucocytic and parasitaemic profiles and immune response of rats treated with retinyl palmitate before infection with Trypanosoma brucei. | Journal of comparative pathology 20031101 |
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei. | Eukaryotic cell 20031001 |
The effects of diminazene aceturate on systemic blood pressure in clinically healthy adult dogs. | Journal of the South African Veterinary Association 20030901 |
Clinical and neuroinflammatory responses to meningoencephalitis in substance P receptor knockout mice. | Brain : a journal of neurology 20030701 |
Field studies of drug-resistant cattle trypanosomes in Kénédougou Province, Burkina Faso. | Acta tropica 20030401 |
Intra-uterine Infection with Babesia bovis in a 2-day-old Calf. | Journal of veterinary medicine. B, Infectious diseases and veterinary public health 20030301 |
Chemotherapy of surra in horses and mules with diminazene aceturate. | Veterinary parasitology 20030102 |
The pathogenicity of diminazene aceturate-resistant Trypanosoma brucei in rats after treatment with the drug. | Journal of comparative pathology 20030101 |
The rare human fragile site 16B. | Cytogenetic and genome research 20030101 |
Liquid chromatographic determination of diminazene diaceturate (Berenil) in raw bovine milk. | Journal of AOAC International 20030101 |
Electron paramagnetic resonance dynamic signatures of TAR RNA-small molecule complexes provide insight into RNA structure and recognition. | Biochemistry 20021217 |
Determination of diminazene aceturate in pharmaceutical formulations by HPLC and identification of related substances by LC/MS. | Journal of pharmaceutical and biomedical analysis 20021107 |
A competitive enzyme-linked immunosorbent assay for diminazene. | Acta tropica 20021101 |
Financial implications of rearing sheep and goats under natural trypanosomosis challenge at Galana ranch, Kenya. | Tropical animal health and production 20021101 |
Residual effect of antibabesial drugs on the live redwater blood vaccines. | Annals of the New York Academy of Sciences 20021001 |
Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda. | Acta tropica 20021001 |
Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate. | Journal of drug targeting 20020801 |
In vitro cultivation of Chinese strains of Babesia spp. | Parasitology research 20020501 |
Developments in the treatment of leishmaniasis and trypanosomiasis. | Expert opinion on emerging drugs 20020501 |
Screening of acyl hydrazide proteinase inhibitors for antiparasitic activity against Trypanosoma brucei. | International journal of antimicrobial agents 20020301 |
Inhibition of DNA replication by berenil in plasmids containing Poly(dA)poly(dT) sequences. | Plasmid 20020301 |
S-adenosylmethionine decarboxylase from Leishmania donovani. Molecular, genetic, and biochemical characterization of null mutants and overproducers. | The Journal of biological chemistry 20020222 |
Effect of strand orientation on the interaction of berenil with DNA triple helices. | European biophysics journal : EBJ 20020201 |
Discriminating small molecule DNA binding modes by single molecule force spectroscopy. | FEBS letters 20020116 |
Inhibition of DNA replication by berenil of bacterial plasmids containing poly(dA)-poly(dT) sequences. 2D gel analysis of replicative intermediates. | Cellular and molecular biology (Noisy-le-Grand, France) 20020101 |
Changes in properties of adenosine transporters in Trypanosoma evansi and modes of selection of resistance to the melaminophenyl arsenical drug, Mel Cy. | Veterinary parasitology 20011213 |
Enhancing effects of anti-CD40 treatment on the immune response of SCID-bovine mice to Trypanosoma congolense infection. | Journal of leukocyte biology 20011201 |
In vitro effect of alkaloids on bloodstream forms of Trypanosoma brucei and T. congolense. | Planta medica 20011001 |
Drug-resistant Trypanosoma congolense in naturally infected donkeys in north Omo Zone, southern Ethiopia. | Veterinary parasitology 20010831 |
Drug-polyionic block copolymer interactions for micelle formation: physicochemical characterisation. | Journal of controlled release : official journal of the Controlled Release Society 20010810 |
Bioassay-guided studies on the cytotoxic and in vitro trypanocidal activities of a sesquiterpene (Muzigadial) derived from a Ugandan medicinal plant (Warburgia ugandensis). | African health sciences 20010801 |
Heterogeneous DNA binding modes of berenil. | Biochimica et biophysica acta 20010628 |
A simple, high-resolution method for establishing DNA binding affinity and sequence selectivity. | Journal of the American Chemical Society 20010627 |
Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle. | Veterinary parasitology 20010612 |
Concentration-dependent inhibition of sheep erythrocyte ghost plasma membrane Ca2+-ATPase activity by Berenil. | Journal of veterinary pharmacology and therapeutics 20010601 |
DNA minor-groove recognition by small molecules. | Natural product reports 20010601 |
The incidence of new and the prevalence and persistence of recurrent trypanosome infections in cattle in southwest Ethiopia exposed to a high challenge with drug-resistant parasites. | Acta tropica 20010525 |
A comparative evaluation of parasitological tests and a PCR for Trypanosoma evansi diagnosis in experimentally infected water buffaloes. | Veterinary parasitology 20010509 |
Transporters in African trypanosomes: role in drug action and resistance. | International journal for parasitology 20010501 |
Effect of clindamycin therapy on phagocytic and oxidative activity profiles of spleen mononuclear cells in Babesia rodhaini-infected mice. | The Journal of veterinary medical science 20010501 |
Validation of a polymerase chain reaction assay for monitoring the therapeutic efficacy of diminazene aceturate in trypanosome-infected sheep. | Veterinary parasitology 20010320 |
Uptake of pentamidine in Trypanosoma brucei brucei is mediated by three distinct transporters: implications for cross-resistance with arsenicals. | Molecular pharmacology 20010301 |
Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice. | Parasitology international 20010301 |
Enhanced lipid peroxide levels in the erythrocytes of calves with haemoglobinuria. | Veterinary research communications 20010101 |
In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga. | Drugs under experimental and clinical research 20010101 |
Highly potent synthetic polyamides, bisdistamycins, and lexitropsins as inhibitors of human immunodeficiency virus type 1 integrase. | Molecular pharmacology 19980801 |
Linked lexitropsins and the in vitro inhibition of HIV-1 reverse transcriptase RNA-directed DNA polymerization: a novel induced-fit of 3,5 m-pyridyl bisdistamycin to enzyme-associated template-primer. | Biochemistry 19961203 |
Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro. | Annals of tropical medicine and parasitology 19961201 |
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii. | Journal of medicinal chemistry 19951124 |
DNA-binding activity and biological effects of aromatic polyamidines. | Biochemical pharmacology 19940211 |
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia. | Antimicrobial agents and chemotherapy 19880801 |
Cationic antitrypanosomal and other antimicrobial agents in the therapy of experimental Pneumocystis carinii pneumonia. | Antimicrobial agents and chemotherapy 19880601 |
Antifungal and antibacterial activities of diarylamidine derivatives. | Antimicrobial agents and chemotherapy 19800801 |