Home Other Building Blocks 2-(3-(4-Pentylphenyl)acrylamido)benzoic acid

2-(3-(4-Pentylphenyl)acrylamido)benzoic acid

CAS No.:
110683-10-8
Catalog Number:
AG0039NS
Molecular Formula:
C21H23NO3
Molecular Weight:
337.4122
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
≥95%
1 week
United States
$125
- +
50mg
≥95%
1 week
United States
$160
- +
100mg
≥95%
1 week
United States
$247
- +
250mg
≥95%
1 week
United States
$432
- +
Product Description
Catalog Number:
AG0039NS
Chemical Name:
2-(3-(4-Pentylphenyl)acrylamido)benzoic acid
CAS Number:
110683-10-8
Molecular Formula:
C21H23NO3
Molecular Weight:
337.4122
MDL Number:
MFCD00211365
IUPAC Name:
2-[[(E)-3-(4-pentylphenyl)prop-2-enoyl]amino]benzoic acid
InChI:
InChI=1S/C21H23NO3/c1-2-3-4-7-16-10-12-17(13-11-16)14-15-20(23)22-19-9-6-5-8-18(19)21(24)25/h5-6,8-15H,2-4,7H2,1H3,(H,22,23)(H,24,25)/b15-14+
InChI Key:
GAMRBCZMOOMBSQ-CCEZHUSRSA-N
SMILES:
CCCCCc1ccc(cc1)C=CC(=O)Nc1ccccc1C(=O)O
Properties
Complexity:
452  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
337.168g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
337.419g/mol
Monoisotopic Mass:
337.168g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
66.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
6.4  
Literature
Title Journal
Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitro. Toxicological sciences : an official journal of the Society of Toxicology 20111101
Inhibition of the calcium-activated chloride current in cardiac ventricular myocytes by N-(p-amylcinnamoyl)anthranilic acid (ACA). Biochemical and biophysical research communications 20101119
Inhibitors of TRP channels reveal stimulus-dependent differential activation of Ca2+ influx pathways in human neutrophil granulocytes. Naunyn-Schmiedeberg's archives of pharmacology 20091201
Acute action of rotenone on nigral dopaminergic neurons--involvement of reactive oxygen species and disruption of Ca2+ homeostasis. The European journal of neuroscience 20091101
H2O2-induced Ca2+ influx and its inhibition by N-(p-amylcinnamoyl) anthranilic acid in the beta-cells: involvement of TRPM2 channels. Journal of cellular and molecular medicine 20090901
Inhibition of the transient receptor potential cation channel TRPM2 by 2-aminoethoxydiphenyl borate (2-APB). British journal of pharmacology 20080301
Phospholipase A2 is important for glucose induction of rhythmic Ca2+ signals in pancreatic beta cells. Pancreas 20070801
N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A(2) inhibitor and TRP channel blocker. Cardiovascular drug reviews 20070101
Prostaglandin E2 release in gastric antral mucosa of guinea-pigs: basal PGE2 release by cyclo-oxygenase 2 and ACh-stimulated PGE2 release by cyclo-oxygenase 1. Experimental physiology 20061101
Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid. British journal of pharmacology 20060601
Enhancement of Ca2+-regulated exocytosis by indomethacin in guinea-pig antral mucous cells: arachidonic acid accumulation. Experimental physiology 20060101
Arachidonyltrifluoromethy ketone, a phospholipase A(2) antagonist, induces dispersal of both Golgi stack- and trans Golgi network-resident proteins throughout the cytoplasm. Biochemical and biophysical research communications 20010223
Properties