Home Other Building Blocks Methyl 4-hydroxybenzoate

Methyl 4-hydroxybenzoate

CAS No.:
99-76-3
Catalog Number:
AG0039N3
Molecular Formula:
C8H8O3
Molecular Weight:
152.1473
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10g
95%
In Stock USA
United States
$13
- +
25g
95%
In Stock USA
United States
$19
- +
100g
98%
In Stock USA
United States
$50
- +
500g
98%
In Stock USA
United States
$188
- +
Product Description
Catalog Number:
AG0039N3
Chemical Name:
Methyl 4-hydroxybenzoate
CAS Number:
99-76-3
Molecular Formula:
C8H8O3
Molecular Weight:
152.1473
MDL Number:
MFCD00002352
IUPAC Name:
methyl 4-hydroxybenzoate
InChI:
InChI=1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
InChI Key:
LXCFILQKKLGQFO-UHFFFAOYSA-N
SMILES:
COC(=O)c1ccc(cc1)O
UNII:
A2I8C7HI9T
FEMA Number:
2710
RTECS Number:
DH2450000
Properties
Complexity:
136  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
152.047g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
152.149g/mol
Monoisotopic Mass:
152.047g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
46.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2  
Literature
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Evaluation of an aminobisphosphonate (alendronate) in the management of periodontal osseous defects. Journal of Indian Society of Periodontology 20100101
Metabolism of parabens (4-hydroxybenzoic acid esters) by hepatic esterases and UDP-glucuronosyltransferases in man. Drug metabolism and pharmacokinetics 20100101
Removal of parabens from aqueous solution using β-cyclodextrin cross-linked polymer. International journal of molecular sciences 20100101
Development of a multicommutated flow system with chemiluminometric detection for quantification of gentamicin in pharmaceuticals. Journal of automated methods & management in chemistry 20100101
Differential volatile signatures from skin, naevi and melanoma: a novel approach to detect a pathological process. PloS one 20100101
Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse. BMC infectious diseases 20100101
Assessment of viscoelasticity and hydration effect of herbal moisturizers using bioengineering techniques. Pharmacognosy magazine 20100101
A New Validated HPLC Method for the Simultaneous Determination of 2-phenoxyethanol, Methylparaben, Ethylparaben and Propylparaben in a Pharmaceutical Gel. Indian journal of pharmaceutical sciences 20100101
Adverse effects of local anaesthetics - allergy, toxic reactions or hypersensitivity. Anestezjologia intensywna terapia 20100101
Evaluation of a microbial inhibitor in artificial diets of a generalist caterpillar, Heliothis virescens. Journal of insect science (Online) 20100101
Genotoxicity of lapachol evaluated by wing spot test of Drosophila melanogaster. Genetics and molecular biology 20100101
Probabilistic ecological hazard assessment of parabens using Daphnia magna and Pimephales promelas. Environmental toxicology and chemistry 20091201
An evaluation of estrogenic activity of parabens using uterine calbindin-d9k gene in an immature rat model. Toxicological sciences : an official journal of the Society of Toxicology 20091101
Stability of the conjugated species of environmental phenols and parabens in human serum. Environment international 20091101
[Synthesis and identification of artificial antigen to the common moiety of some organophosphorus pesticides]. Wei sheng yan jiu = Journal of hygiene research 20091101
Ultra-high-performance liquid chromatography-tandem mass spectrometry for determining the presence of eleven personal care products in surface and wastewaters. Journal of chromatography. A 20091016
Relating solubility data of parabens in liquid PEG 400 to the behaviour of PEG 4000-parabens solid dispersions. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091001
Antiinflammatory and lipoxygenase inhibitory compounds from Vitex agnus-castus. Phytotherapy research : PTR 20090901
Polycarbonate bottle use and urinary bisphenol A concentrations. Environmental health perspectives 20090901
Combination of off-line solid-phase extraction and on-column sample stacking for sensitive determination of parabens and p-hydroxybenzoic acid in waters by non-aqueous capillary electrophoresis. Analytica chimica acta 20090804
Analysis of parabens in cosmetics by low pressure liquid chromatography with monolithic column and chemiluminescent detection. Talanta 20090715
Estrogenicity of parabens revisited: impact of parabens on early pregnancy and an uterotrophic assay in mice. Reproductive toxicology (Elmsford, N.Y.) 20090701
Expression of Candida glabrata adhesins after exposure to chemical preservatives. The Journal of infectious diseases 20090615
Investigation of the permeation of model formulations and a commercial ibuprofen formulation in Carbosil and human skin using ATR-FTIR and multivariate spectral analysis. International journal of pharmaceutics 20090605
Combined online spectroscopic, calorimetric, and chemometric analysis: reaction enthalpy determinations in single and parallel reactions. Chemphyschem : a European journal of chemical physics and physical chemistry 20090602
Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens). Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601
Novel natural parabens produced by a Microbulbifer bacterium in its calcareous sponge host Leuconia nivea. Environmental microbiology 20090601
Simultaneous determination of parabens, triclosan and triclocarban in water by liquid chromatography/electrospray ionisation tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20090601
Simultaneous determination of pseudoephdrine, pheniramine, guaifenisin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold medicines by high performance liquid chromatography. Talanta 20090515
Modeling the phase behavior in mixtures of pharmaceuticals with liquid or supercritical solvents. The journal of physical chemistry. B 20090507
Growth, structural, spectroscopic and optical studies of pure and amino acid (glycine) doped methyl-para-hydroxy benzoate single crystals. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090501
Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. European journal of medicinal chemistry 20090401
Comparative toxicity of preservatives on immortalized corneal and conjunctival epithelial cells. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090401
Dramatic devices?: Medical procedures may expose infants to BPA. Environmental health perspectives 20090401
Exposure to bisphenol A and other phenols in neonatal intensive care unit premature infants. Environmental health perspectives 20090401
Overcoming the nail barrier: A systematic investigation of ungual chemical penetration enhancement. International journal of pharmaceutics 20090331
Crystal structure of ultralente--a microcrystalline insulin suspension. Proteins 20090301
Methylparaben in Anopheles gambiae s.l. sugar meals increases longevity and malaria oocyst abundance but is not a preferred diet. Journal of insect physiology 20090301
In vitro models in biocompatibility assessment for biomedical-grade chitosan derivatives in wound management. International journal of molecular sciences 20090301
Minimally invasive strabismus surgery (MISS) for inferior obliquus recession. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20090201
Suspected anaphylactic reactions associated with anaesthesia. Anaesthesia 20090201
Artificial substrates for oviposition and larval development of the pepper weevil (Coleoptera: Curculionidae). Journal of economic entomology 20090201
Antioxidative iridoid glycosides and phenolic compounds from Veronica peregrina. Archives of pharmacal research 20090201
Parabens in male infertility-is there a mitochondrial connection? Reproductive toxicology (Elmsford, N.Y.) 20090101
Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster. PloS one 20090101
Concentrations of phthalate metabolites in milk, urine, saliva, and Serum of lactating North Carolina women. Environmental health perspectives 20090101
Short-term starvation of immune deficient Drosophila improves survival to gram-negative bacterial infections. PloS one 20090101
Biological activity of secondary metabolites from Peltostigma guatemalense. Natural product research 20090101
Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries. PloS one 20090101
Mutiniside, new antioxidant phenolic glucoside from Abutilon muticum. Journal of Asian natural products research 20090101
Ameliorative effects of ginger extract on paraben-induced lipid peroxidation in the liver of mice. Acta poloniae pharmaceutica 20090101
Benzydamine hydrochloride buccal bioadhesive gels designed for oral ulcers: preparation, rheological, textural, mucoadhesive and release properties. Pharmaceutical development and technology 20090101
Colonisation and mass rearing: learning from others. Malaria journal 20090101
Underarm antiperspirants/deodorants and breast cancer. Breast cancer research : BCR 20090101
Preparation and evaluation of soft gellan gum gel containing paracetamol. Indian journal of pharmaceutical sciences 20090101
Investigation of Hydrogel Isolated from Seeds of Ocimum basilicum as Binder. Indian journal of pharmaceutical sciences 20090101
Development and Validation of HPTLC Method for the Estimation of Clotrimazole in Bulk drug and Tablet Formulation. Indian journal of pharmaceutical sciences 20090101
An in vitro antimicrobial activity of ten Iranian-made toothpastes. Dental research journal 20090101
Development of membrane selective electrode for determination of the antipsychotic sulpiride in pharmaceuticals and urine. Sensors (Basel, Switzerland) 20090101
Subtle structural variation in copper metal-organic frameworks: syntheses, structures, magnetic properties and catalytic behaviour. Dalton transactions (Cambridge, England : 2003) 20081221
Minimally invasive strabismus surgery for horizontal rectus muscle reoperations. The British journal of ophthalmology 20081201
Growth inhibition of bacterial isolates recovered from two types of Portuguese dry smoked sausages (chouriço). Meat science 20081201
Aging predisposes oocytes to meiotic nondisjunction when the cohesin subunit SMC1 is reduced. PLoS genetics 20081101
Simultaneous determination of 21 preservatives in cosmetics by ultra performance liquid chromatography. International journal of cosmetic science 20081001
Effects of mouth rinses on color stability of resin composites. European journal of dentistry 20081001
Separation and determination of ketoprofen, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography. Journal of pharmaceutical and biomedical analysis 20080929
In vitro culturing of porcine tracheal mucosa as an ideal model for investigating the influence of drugs on human respiratory mucosa. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20080901
Control of transdermal permeation of hydrocortisone acetate from hydrophilic and lipophilic formulations. AAPS PharmSciTech 20080901
Construction of simplified models to simulate estrogenic disruptions by esters of 4-hydroxy benzoic acid (parabens). Biophysical chemistry 20080901
Effect of large volume injection of hydrophobic solvents on the retention of less hydrophobic pharmaceutical solutes in RP-LC. Journal of separation science 20080901
[Simultaneous determination of adapalene, 2-phenoxyethanol and methyl-4-hydroxybenzoate in adapalene gels using high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20080901
Simultaneous determination of some water-soluble vitamins and preservatives in multivitamin syrup by validated stability-indicating high-performance liquid chromatography method. Journal of chromatography. A 20080822
Substance flow analysis of parabens in Denmark complemented with a survey of presence and frequency in various commodities. Journal of hazardous materials 20080815
Automated on-line column-switching HPLC-MS/MS method with peak focusing for measuring parabens, triclosan, and other environmental phenols in human milk. Analytica chimica acta 20080801
Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage. Chemical research in toxicology 20080801
Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel. PLoS medicine 20080801
Analysis and quantification of parabens in cosmetic products by utilizing hollow fibre-supported liquid membrane and high performance liquid chromatography with ultraviolet detection. International journal of cosmetic science 20080801
Advantages of pentafluorophenylpropyl stationary phase over conventional C18 stationary phase--application to analysis of triamcinolone acetonide. Talanta 20080730
Predicting blood-brain barrier penetration of drugs by microemulsion liquid chromatography with corrected retention factor. Journal of chromatography. A 20080711
Chemical constituents from leaves of Palicourea coriacea (Rubiaceae). Journal of natural medicines 20080701
A second monoclinic polymorph of methyl 4-hydroxy-benzoate. Acta crystallographica. Section E, Structure reports online 20080701
Cytotoxic activity of Ipomoea cairica. Natural product research 20080615
Association of nicotinamide with parabens: effect on solubility, partition and transdermal permeation. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601
Effect of pharmaceuticals on thermoreversible gelation of PEO-PPO-PEO copolymers. Colloids and surfaces. B, Biointerfaces 20080601
Topical ocular delivery of NSAIDs. The AAPS journal 20080601
[Application of single drop microextraction in the determination of phthalate esters and parabens in drugs by gas chromatography-mass spectrometry]. Se pu = Chinese journal of chromatography 20080501
Pharmaceutical gel analysis by NIR spectroscopy. Determination of the active principle and low concentration of preservatives. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080423
Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans. International journal of andrology 20080401
The impact of meteorological conditions on patch test results with 12 standard series allergens (fragrances, biocides, topical ingredients). The British journal of dermatology 20080401
Lack of effect of butylparaben and methylparaben on the reproductive system in male rats. Birth defects research. Part B, Developmental and reproductive toxicology 20080401
Antimicrobial activity of parabens in submicron emulsions stabilized with lecithin. Drug development and industrial pharmacy 20080401
Sunscreens cause coral bleaching by promoting viral infections. Environmental health perspectives 20080401
Complex etiology, prophylaxis and hygiene control in mycotoxic nephropathies in farm animals and humans. International journal of molecular sciences 20080401
Effect of abrasion induced by a rotating brush on the skin permeation of solutes with varying physicochemical properties. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080301
Percutaneous permeation enhancement by terpenes: mechanistic view. The AAPS journal 20080301
[Study on chemical constituents isolated from Juncus effuses]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080301
Analysis of the antimicrobial activity of local anaesthetics used for dental analgesia. Journal of medical microbiology 20080101
Contact sensitivity in patients with venous leg ulcers in Serbia: comparison with contact dermatitis patients and relationship to ulcer duration. Contact dermatitis 20080101
Paraben allergic contact dermatitis in a patient with livedo reticularis. Contact dermatitis 20080101
New validated liquid chromatographic and chemometrics-assisted UV spectroscopic methods for the determination of two multicomponent cough mixtures in syrup. Journal of AOAC International 20080101
Molecular and cellular limits to somatosensory specificity. Molecular pain 20080101
Simultaneous determination of phenylephrine hydrochloride, guaifenesin, and chlorpheniramine maleate in cough syrup by gradient liquid chromatography. Journal of AOAC International 20080101
North American Contact Dermatitis Group patch-test results, 2003-2004 study period. Dermatitis : contact, atopic, occupational, drug 20080101
Skin protection creams in medical settings: successful or evil? Journal of occupational medicine and toxicology (London, England) 20080101
Successful desensitization with human insulin in a patient with an insulin allergy and hypersensitivity to protamine: a case report. Journal of medical case reports 20080101
An isocratic reversed-phase high-performance liquid chromatographic method for the simultaneous determination of benzoyl peroxide and the related compounds benzoic acid, benzaldehyde, ethyl benzoate, methylparaben, and propylparaben in dermal preparations. Journal of AOAC International 20080101
Simultaneous high-performance liquid chromatographic determination of telmisartan and hydrochlorothiazide in pharmaceutical preparation. Journal of chromatographic science 20080101
Synthesis, anticonvulsant and neurotoxicity evaluation of 5-carbomethoxybenzoxazole derivatives. Acta poloniae pharmaceutica 20080101
The role of polyamines in protein-dependent hypoxic tolerance of Drosophila. BMC physiology 20080101
Final amended report on the safety assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben, and Benzylparaben as used in cosmetic products. International journal of toxicology 20080101
Abstracts of papers presented at the 2008 pittsburgh conference. Journal of automated methods & management in chemistry 20080101
Anaphylactic shock following intraurethral lidocaine administration during transurethral resection of the prostate. Indian journal of urology : IJU : journal of the Urological Society of India 20080101
Influence of crystal structure on the tableting properties of n-alkyl 4-hydroxybenzoate esters (parabens). Journal of pharmaceutical sciences 20071201
Antimicrobial preservative use in parenteral products: past and present. Journal of pharmaceutical sciences 20071201
Hydrolysis of a series of parabens by skin microsomes and cytosol from human and minipigs and in whole skin in short-term culture. Toxicology and applied pharmacology 20071201
Combining esters of para-hydroxy benzoic acid (parabens) to achieve increased antimicrobial activity. Journal of clinical pharmacy and therapeutics 20071201
Large-volume sample stacking for the analysis of seven beta-lactam antibiotics in milk samples of different origins by CZE. Electrophoresis 20071101
Sustained ocular drug delivery from a temperature and pH triggered novel in situ gel system. Drug delivery 20071101
A high-performance liquid chromatography and nuclear magnetic resonance spectroscopy-based analysis of commercially available praziquantel tablets. Journal of pharmaceutical and biomedical analysis 20071018
Assessment of principal parabens used in cosmetics after their passage through human epidermis-dermis layers (ex-vivo study). Experimental dermatology 20071001
In vitro skin permeation and retention of parabens from cosmetic formulations. International journal of cosmetic science 20071001
Inter-individual variability in esterases in human liver. Biochemical pharmacology 20070915
Temporal stability of the conjugated species of bisphenol A, parabens, and other environmental phenols in human urine. Journal of exposure science & environmental epidemiology 20070901
A successful virtual screening application: prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben. Journal of computer-aided molecular design 20070901
20 Years of standard patch testing in an eczema population with focus on patients with multiple contact allergies. Contact dermatitis 20070801
Simultaneous identification and quantification by liquid chromatography of benzethonium chloride, methyl paraben and triclosan in commercial products labeled as grapefruit seed extract. Die Pharmazie 20070801
Simultaneous determination of antioxidants, preservatives and sweetener additives in food and cosmetics by flow injection analysis coupled to a monolithic column. Analytica chimica acta 20070702
Automated semipreparative purification with mass spectrometric fraction collection trigger: modeling and experimental evaluation of a setup employing passive splitting. Journal of separation science 20070701
Effect of preservatives on ciliary beat frequency in human nasal epithelial cell culture: single versus multiple exposure. International journal of pharmaceutics 20070629
A further characteristic of susceptibility to contact allergy: sensitization to a weak contact allergen is associated with polysensitization. Results of the IVDK. Contact dermatitis 20070601
Mycoflora of two types of Portuguese dry-smoked sausages and inhibitory effect of sodium benzoate, potassium sorbate, and methyl p-hydroxybenzoate on mold growth rate. Journal of food protection 20070601
[Simultaneous determination of nine kinds of preservatives in foods by HPLC]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20070601
Synthesis and biological evaluation of 12 allenic aromatic ethers. Bioorganic & medicinal chemistry letters 20070515
Methyl p-hydroxybenzoate causes pain sensation through activation of TRPA1 channels. British journal of pharmacology 20070501
Inhibition of conidia germination and mycelial growth of Botrytis cinerea by some alternative chemicals. Pakistan journal of biological sciences : PJBS 20070415
Parabens inhibit human skin estrogen sulfotransferase activity: possible link to paraben estrogenic effects. Toxicology 20070411
Phenotypic alterations and cytokine production in THP-1 cells in response to allergens. Toxicology in vitro : an international journal published in association with BIBRA 20070401
Variability in human skin permeability in vitro: comparing penetrants with different physicochemical properties. Journal of pharmaceutical sciences 20070401
Comparison of objective and sensory skin irritations of several cosmetic preservatives. Contact dermatitis 20070301
[Simultaneous determination of phthalates and parabens in cosmetic products by gas chromatography/mass spectrometry coupled with solid phase extraction]. Se pu = Chinese journal of chromatography 20070301
Development and validation of chemometrics-assisted spectrophotometric and liquid chromatographic methods for the simultaneous determination of two multicomponent mixtures containing bronchodilator drugs. Journal of pharmaceutical and biomedical analysis 20070219
Paraben transport and metabolism in the biomimetic artificial membrane permeability assay (BAMPA) and 3-day and 21-day Caco-2 cell systems. Journal of biomolecular screening 20070201
Prediction of preservative sensitization potential using surface marker CD86 and/or CD54 expression on human cell line, THP-1. Archives of dermatological research 20070201
Effects-directed analysis of organic toxicants in wastewater effluent from Zagreb, Croatia. Chemosphere 20070201
Assay of artemether, methylparaben and propylparaben in a formulated paediatric antimalarial dry suspension. Journal of pharmaceutical and biomedical analysis 20070117
Controlled drug release from pellets containing water-insoluble drugs dissolved in a self-emulsifying system. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070101
Comparison of the global gene expression profiles produced by methylparaben, n-butylparaben and 17beta-oestradiol in MCF7 human breast cancer cells. Journal of applied toxicology : JAT 20070101
Effects of methyl paraben on skin keratinocytes. Journal of applied toxicology : JAT 20070101
Post-marketing assessment of content and efficacy of preservatives in artemisinin-derived antimalarial dry suspensions for paediatric use. Malaria journal 20070101
Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods. Journal of separation science 20070101
Study of hydroxy propyl guar derivative for its gelling property and it's use in the formulation of tenoxicam gels. Pakistan journal of pharmaceutical sciences 20070101
Determination of the analgesic components of Spasmomigraine tablet by liquid chromatography with ultraviolet detection. Journal of AOAC International 20070101
Optimized determination method for trans-10-hydroxy-2-decenoic acid content in royal jelly by high-performance liquid chromatography with an internal standard. Journal of AOAC International 20070101
Application of a validated method in the stability study of colistin sulfate and methylparaben in a veterinary suspension formulation by high-performance liquid chromatography with a diode array detector. Journal of AOAC International 20070101
Antioxidative effect of rhizome of Zinziber officinale on paraben induced lipid peroxidation: an in vitro study. Acta poloniae pharmaceutica 20070101
Ginger extract ameliorates paraben induced biochemical changes in liver and kidney of mice. Acta poloniae pharmaceutica 20070101
Estrogenic personal care products in a greywater reuse system. Water science and technology : a journal of the International Association on Water Pollution Research 20070101
Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. BMC structural biology 20070101
A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients. Radiation oncology (London, England) 20070101
Immune system responses and fitness costs associated with consumption of bacteria in larvae of Trichoplusia ni. BMC biology 20070101
L-glutamic acid in the prevention of the calcification of bovine pericardial fixed in glutaraldehyde: study in rats. Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular 20070101
Comparison of paraben stability in human and rat skin. Drug metabolism letters 20070101
Effect of formulation factors on in-vitro permeation of diclofenac from experimental and marketed aqueous eye drops through excised goat cornea. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061201
Parabens as urinary biomarkers of exposure in humans. Environmental health perspectives 20061201
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of molecular graphics & modelling 20061101
Permeation of 4-cyanophenol and methyl paraben from powder and saturated aqueous solution through silicone rubber membranes and human skin. Journal of pharmaceutical sciences 20061101
Advantages of ultra performance liquid chromatography over high-performance liquid chromatography: comparison of different analytical approaches during analysis of diclofenac gel. Journal of separation science 20061101
Methylparaben potentiates UV-induced damage of skin keratinocytes. Toxicology 20061003
Flow cytometric cell cycle analysis allows for rapid screening of estrogenicity in MCF-7 breast cancer cells. Toxicology in vitro : an international journal published in association with BIBRA 20061001
Solid-phase extraction and HPLC analysis of methylparaben and propylparaben in a concentrated antibiotic suspension. Drug development and industrial pharmacy 20061001
Quantitation of buclizine hydrochloride in pharmaceutical formulations and human serum by RP-HPLC. Pakistan journal of pharmaceutical sciences 20061001
Fast simultaneous spectrophotometric determination of naphazoline nitrate and methylparaben by sequential injection chromatography. Talanta 20060915
Transesterification of p-hydroxybenzoate esters (parabens) by human intestinal (Caco-2) cells. Xenobiotica; the fate of foreign compounds in biological systems 20060901
Formation of halogenated by-products of parabens in chlorinated water. Analytica chimica acta 20060804
Causal agents of photoallergic contact dermatitis diagnosed in the national institute of dermatology of Colombia. Photodermatology, photoimmunology & photomedicine 20060801
A model for the drug release from a polymer matrix tablet--effects of swelling and dissolution. Journal of controlled release : official journal of the Controlled Release Society 20060720
Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry. Journal of chromatography. A 20060707
Influence of crystal structure on the compaction properties of n-alkyl 4-hydroxybenzoate esters (parabens). Pharmaceutical research 20060701
Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup. Journal of pharmaceutical and biomedical analysis 20060607
Solitary pancreas transplantation for life-threatening allergy to human insulin. Transplant international : official journal of the European Society for Organ Transplantation 20060601
Application and validation of chemometrics-assisted spectrophotometry and liquid chromatography for the simultaneous determination of six-component pharmaceuticals. Journal of pharmaceutical and biomedical analysis 20060503
Stability indicating simultaneous determination of domperidone (DP), methylparaben (MP) and propylparaben by high performance liquid chromatography (HPLC). Journal of pharmaceutical and biomedical analysis 20060503
HPLC determination of calcium pantothenate and two preservatives in topical cream. Journal of pharmaceutical and biomedical analysis 20060503
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Partitioning of parabens between phases of submicron emulsions stabilized with egg lecithin. International journal of pharmaceutics 20060407
Enterobacter gergoviae and the prevalence of efflux in parabens resistance. The Journal of antimicrobial chemotherapy 20060401
Release of antimicrobial actives from microcapsules by the action of axillary bacteria. International journal of cosmetic science 20060401
A stability-indicating HPLC method for medroxyprogesterone acetate in bulk drug and injection formulation. Journal of pharmaceutical and biomedical analysis 20060318
Percutaneous dermal drug delivery for local pain control. Therapeutics and clinical risk management 20060301
Determination of ambroxol hydrochloride, methylparaben and benzoic acid in pharmaceutical preparations based on sequential injection technique coupled with monolithic column. Journal of pharmaceutical and biomedical analysis 20060213
Allergic and systemic contact dermatitis to methylparaben. Contact dermatitis 20060201
Separation and determination of clotrimazole, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography. Journal of pharmaceutical and biomedical analysis 20060123
Advantages of application of UPLC in pharmaceutical analysis. Talanta 20060115
Comparison of two pressure ulcer preventive dressings for reducing shear force on the heel. Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20060101
Chemical constituents from the roots of Ranunculus ternatus. Journal of Asian natural products research 20060101
Single and multiple dose pharmacokinetics of maritime pine bark extract (pycnogenol) after oral administration to healthy volunteers. BMC clinical pharmacology 20060101
The importance of the cosolvent propylene glycol on the antimicrobial preservative efficacy of a pharmaceutical formulation by DOE-ruggedness testing. Pharmaceutical development and technology 20060101
LIGSITEcsc: predicting ligand binding sites using the Connolly surface and degree of conservation. BMC structural biology 20060101
The influence of physicochemical properties of preservative compounds on their distribution into various phases of oil in water submicron emulsion. PDA journal of pharmaceutical science and technology 20060101
Acceleration of paraben sorption to polyethylene terephthalate: a freeze-thaw phenomenon. PDA journal of pharmaceutical science and technology 20060101
A low protein diet increases the hypoxic tolerance in Drosophila. PloS one 20060101
Aqueous ginger extract ameliorates paraben induced cytotoxicity. Acta poloniae pharmaceutica 20060101
RNAi knockdown of a salivary transcript leading to lethality in the pea aphid, Acyrthosiphon pisum. Journal of insect science (Online) 20060101
p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis. The Journal of biological chemistry 20051209
Microflora species and their volatile compounds affecting development of an alcohol dehydrogenase homozygous strain (Adh-I) of Bactrocera (Dacus) oleae (Diptera: Tephritidae). Journal of economic entomology 20051201
[A silicon phthalocyanine axially substituted by nipagin: synthesis, molecular spectroscopic properties, and in vitro photodynamic activities]. Guang pu xue yu guang pu fen xi = Guang pu 20051001
A comparison of performance of various analytical columns in pharmaceutical analysis: conventional C18 and high throughput C18 zorbax columns. Journal of chromatography. A 20050923
Stability indicating reversed-phase liquid chromatographic determination of metronidazole benzoate and diloxanide furoate as bulk drug and in suspension dosage form. Journal of pharmaceutical and biomedical analysis 20050915
Determination of parabens in pharmaceutical formulations by solid-phase microextraction-ion mobility spectrometry. Analytical chemistry 20050915
The effect of unsaturated fatty acids in benzyl alcohol on the percutaneous permeation of three model penetrants. International journal of pharmaceutics 20050914
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Journal of medicinal chemistry 20050908
High performance liquid chromatographic determination of oxeladin citrate and oxybutynin hydrochloride and their degradation products. Farmaco (Societa chimica italiana : 1989) 20050801
A novel gradient HPLC method for simultaneous determination of ranitidine, methylparaben and propylparaben in oral liquid pharmaceutical formulation. Journal of pharmaceutical and biomedical analysis 20050715
Safety assessment of esters of p-hydroxybenzoic acid (parabens). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050701
Propyl paraben induces potassium efflux in Escherichia coli. The Journal of antimicrobial chemotherapy 20050601
Parabens: a review of epidemiology, structure, allergenicity, and hormonal properties. Dermatitis : contact, atopic, occupational, drug 20050601
A review of the endocrine activity of parabens and implications for potential risks to human health. Critical reviews in toxicology 20050601
Novel solid-phase extraction protocol for 11-nor-9-carboxy-delta9-tetrahydrocannabinol from urine samples employing a polymeric mixed-mode cation-exchange resin, Strata-X-C, suitable for gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry analysis. Journal of chromatography. A 20050506
Simultaneous determination of preservatives (benzoic acid, sorbic acid, methylparaben and propylparaben) in foodstuffs using high-performance liquid chromatography. Journal of chromatography. A 20050506
Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PLoS medicine 20050501
Stability assessment of pharmaceuticals by isothermal calorimetry: two component systems. International journal of pharmaceutics 20050323
The use of colloidal microgels as a (trans)dermal drug delivery system. International journal of pharmaceutics 20050323
Development and validation of a stability indicating HPLC method for determination of lisinopril, lisinopril degradation product and parabens in the lisinopril extemporaneous formulation. Journal of pharmaceutical and biomedical analysis 20050309
Inter- and intralaboratory variation of in vitro diffusion cell measurements: an international multicenter study using quasi-standardized methods and materials. Journal of pharmaceutical sciences 20050301
Decrease in skin permeation and antibacterial effect of parabens by a polymeric additive, poly(2-methacryloyloxyethyl phosphorylcholine-co-butylmetacrylate). Chemical & pharmaceutical bulletin 20050301
Estrogenic activity of cosmetic components in reporter cell lines: parabens, UV screens, and musks. Journal of toxicology and environmental health. Part A 20050227
[Synthesis of 2,3,4-trihydroxyacetophenone hydrazones and study on their spectral properties]. Guang pu xue yu guang pu fen xi = Guang pu 20050201
Partition of antimicrobial additives in an intravenous emulsion and their effect on emulsion physical stability. International journal of pharmaceutics 20050120
Thermodynamics of solubility, sublimation and solvation processes of parabens. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101
Oestrogenic activity of p-hydroxybenzoic acid (common metabolite of paraben esters) and methylparaben in human breast cancer cell lines. Journal of applied toxicology : JAT 20050101
Liquid chromatography and chemometric-assisted spectrophotometric methods for the analysis of two multicomponent mixtures containing cough suppressant drugs. Journal of AOAC International 20050101
Metabolism of xenobiotics in the incubated hen's egg: investigations with ethyl 4-hydroxybenzoate. ALTEX 20050101
[Studies for analyzing the prohibited ingredients such as acetohexamide in cosmetics]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20050101
Influence of diet on the larval beet armyworm, Spodoptera exigua, glucose oxidase activity. Journal of insect science (Online) 20050101
HPLC analysis of generic antiretroviral drugs purchased in Rwanda. Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg 20050101
Separation of preservatives in cosmetic products by micellar electrokinetic chromatography. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20041201
Simultaneous HPLC determination of ketoprofen and its degradation products in the presence of preservatives in pharmaceuticals. Journal of pharmaceutical and biomedical analysis 20041115
Characterization of three glycosyltransferases involved in the biosynthesis of the phenolic glycolipid antigens from the Mycobacterium tuberculosis complex. The Journal of biological chemistry 20041008
Prevalence and relevance of contact dermatitis allergens: a meta-analysis of 15 years of published T.R.U.E. test data. Journal of the American Academy of Dermatology 20040901
Morphometric analysis of mice uteri treated with the preservatives methyl, ethyl, propyl, and butylparaben. Toxicology and industrial health 20040901
Allergic contact dermatitis to condoms: description of a clinical case and analytical review of current literature. Immunopharmacology and immunotoxicology 20040801
HPLC determination of estradiol, its degradation product, and preservatives in new topical formulation Estrogel HBF. Analytical and bioanalytical chemistry 20040701
Single crystal EPR studies of an organic NLO material: methyl-p-hydroxy benzoate. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040701
Solvent effects on infrared spectra of methyl 4-hydroxybenzoate in pure organic solvents and in ethanol/CCl4 binary solvents. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040601
Allergic contact sensitivity in elderly patients. Aging clinical and experimental research 20040601
Burkholderia cepacia infections associated with intrinsically contaminated ultrasound gel: the role of microbial degradation of parabens. Infection control and hospital epidemiology 20040401
Comparison of equations describing band broadening in high-performance liquid chromatography. Journal of chromatography. A 20040319
Measurement of anti-HIV activity of marketed vaginal products and excipients using a PBMC-based in vitro assay. Sexually transmitted diseases 20040301
Effect of heat on the percutaneous absorption and skin retention of three model penetrants. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040201
Simultaneous determination of metformin in combination with rosiglitazone by reversed-phase liquid chromatography. Journal of chromatographic science 20040201
Determination of combined p-hydroxy benzoic acid preservatives in a liquid pharmaceutical formulation by HPLC. Journal of pharmaceutical and biomedical analysis 20040127
Concentrations of parabens in human breast tumours. Journal of applied toxicology : JAT 20040101
Simultaneous high-performance liquid chromatographic determination of pioglitazone and metformin in pharmaceutical-dosage form. Journal of chromatographic science 20040101
Release of simulated anthrax particles from disposable respirators. Journal of occupational and environmental hygiene 20040101
Preventing sexual transmission of HIV: anti-HIV bioregulatory and homeostatic components of commercial sexual lubricants. Journal of biological regulators and homeostatic agents 20040101
Phenolic compounds and flavonoids as plant growth regulators from fruit and leaf of Vitex rotundifolia. Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
The physical stability of thermally-stressed phospholipid-based emulsions containing methyl, propyl and heptyl parabens as model drugs. International journal of pharmaceutics 20031020
Reversed-phase porous silica rods, an alternative approach to high-performance liquid chromatographic separation using the sequential injection chromatography technique. Journal of chromatography. A 20031010
Antiprotozoal activities of symmetrical bishydroxamic acids. Bioorganic & medicinal chemistry 20031001
Determination of bifonazole in creams containing methyl- and propyl p-hydroxybenzoate by derivative spectrophotometric method. Journal of pharmaceutical and biomedical analysis 20030915
[Evaluation of interaction between drugs and ordered phospholipid membrane by immobilized artificial membrane chromatography]. Yao xue xue bao = Acta pharmaceutica Sinica 20030901
Crystallization of two forms of a cyclodextrin inclusion complex containing a common organic guest. Chemical communications (Cambridge, England) 20030821
Simultaneous determination of methylparaben, propylparaben, hydrocortisone acetate and its degradation products in a topical cream by RP-HPLC. Journal of pharmaceutical and biomedical analysis 20030808
Influence of methylparaben as a solid-state plasticizer on the physicochemical properties of Eudragit RS PO hot-melt extrudates. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20030701
In vivo and in vitro estrogen bioactivities of alkyl parabens. Toxicology and industrial health 20030701
Determination of methylparaben, propylparaben, triamcinolone acetonide and its degradation product in a topical cream by RP-HPLC. Analytical and bioanalytical chemistry 20030601
Development of a multidose formulation for a humanized monoclonal antibody using experimental design techniques. AAPS pharmSci 20030601
Effects of methyl p-hydroxybenzoate (methyl paraben) on Ca2+ concentration and histamine release in rat peritoneal mast cells. British journal of pharmacology 20030501
Metabolic profiling of root exudates of Arabidopsis thaliana. Journal of agricultural and food chemistry 20030423
Allergy and toxic reactions to local anesthetics. Dentistry today 20030401
Antioxidant properties and phytochemical characteristics of extracts from Lactuca indica. Journal of agricultural and food chemistry 20030226
p-Hydroxybenzoic acid alkyl esters in Andrographis paniculata herbs, commercial extracts, and formulated products. Journal of agricultural and food chemistry 20030115
Oestrogenic activity of benzylparaben. Journal of applied toxicology : JAT 20030101
Vasoactive properties of lignocaine administered by iontophoresis in human skin. Clinical science (London, England : 1979) 20030101
Determination of methylparaben in o/w emulsions by solid-phase extraction and high-performance liquid chromatography. Journal of cosmetic science 20030101
Diffusion of preservatives from topical dosage forms: a comparative study. Journal of cosmetic science 20030101
Solvent effects in permeation assessed in vivo by skin surface biopsy. BMC dermatology 20030101
[Studies for analyzing phenoxyethanol and parabens in commercial lotions]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20030101
Larvicidal effects of mineral turpentine, low aromatic white spirits, aqueous extracts of Cassia alata, and aqueous extracts, ethanolic extracts and essential oil of betel leaf (Piper betle) on Chrysomya megacephala. International journal of dermatology 20021201
Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata. Journal of natural products 20021101
Evaluation of the health aspects of methyl paraben: a review of the published literature. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001
Estimating vapor pressure curves by thermogravimetry: a rapid and convenient method for characterization of pharmaceuticals. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020901
Fast capillary electrochromatographic analysis of parabens and 4-hydroxybenzoic acid in drugs and cosmetics. Electrophoresis 20020901
Interaction of methylparaben preservative with selected sugars and sugar alcohols. Journal of pharmaceutical sciences 20020701
Elucidation of solid-state complexation in ground mixtures of cholic acid and guest compounds. Chemical & pharmaceutical bulletin 20020701
Derivative spectrophotometric determination of droperidol in presence of parabens. Journal of pharmaceutical and biomedical analysis 20020620
Photobleaching of compounds of the 5,10,15,20-Tetrakis(m-hydroxyphenyl)porphyrin Series (m-THPP, m-THPC, and m-THPBC). Organic letters 20020613
Identification of methyl salicylate as the principal volatile component in the methanol extract of root bark of Securidaca longepedunculata Fers. Journal of mass spectrometry : JMS 20020601
[Analysis of preservatives in cosmetics by gas chromatography]. Se pu = Chinese journal of chromatography 20020501
The effect of ethanol on the simultaneous transport and metabolism of methyl p-hydroxybenzoate in excised skin of Yucatan micropig. International journal of pharmaceutics 20020402
An evaporation study for phthalic acids--a rapid method for pharmaceutical characterization. Journal of pharmaceutical sciences 20020401
Effect of antifungal agents on biological fitness of Lygus hesperus (Heteroptera: Miridae). Journal of economic entomology 20020401
High-performance liquid chromatographic method for the assay of dexamethasone and xylometazoline in nasal drops containing methyl p-hydroxybenzoate. Journal of chromatography. A 20020308
HPLC and LC-MS studies of the transesterification reaction of methylparaben with twelve 3- to 6-carbon sugar alcohols and propylene glycol and the isomerization of the reaction products by acyl migration. Journal of chromatographic science 20020301
The effect of surface charge and partition coefficient on the chemical stability of solutes in O/W emulsions. Journal of pharmaceutical sciences 20020201
The influence of model drugs on the preparation of pellets by extrusion/spheronization: II. Spheronization parameters. International journal of pharmaceutics 20020101
Sorption of benzoic acid, sorbic acid, benzyl alcohol, and benzalkonium chloride by flexible tubing. Pharmaceutical development and technology 20020101
Oestrogenic activity of parabens in MCF7 human breast cancer cells. The Journal of steroid biochemistry and molecular biology 20020101
Patch test results in 542 patients with suspected contact dermatitis in Turkey. Contact dermatitis 20020101
Oestrogenic activity of isobutylparaben in vitro and in vivo. Journal of applied toxicology : JAT 20020101
Spalling and sorption of tubing for peristaltic pumps. Pharmaceutical development and technology 20020101
[Allergic contact eczema caused by henna tattoo]. Allergologia et immunopathologia 20020101
Alkaloids of Thalictrum angustifolium. Journal of herbal pharmacotherapy 20020101
ER-dependent estrogenic activity of parabens assessed by proliferation of human breast cancer MCF-7 cells and expression of ERalpha and PR. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20011201
Electro-hydrodynamic atomization of drug solutions for inhalation purposes. Journal of applied physiology (Bethesda, Md. : 1985) 20011201
Antibacterial effect of parabens against planktonic and biofilm Streptococcus sobrinus. International journal of antimicrobial agents 20011201
Shellac formulations to reduce epiphytic survival of coliform bacteria on citrus fruit postharvest. Journal of food protection 20011101
Sorption of parabens by flexible tubings. Pharmaceutical development and technology 20010801
Selective and quantitative analysis of 4-hydroxybenzoate preservatives by microemulsion electrokinetic chromatography. Journal of chromatography. A 20010727
Sustained prediction ability of net analyte preprocessing methods using reduced calibration sets. Theoretical and experimental study involving the spectrophotometric analysis of multicomponent mixtures. The Analyst 20010701
Safety assessment of propyl paraben: a review of the published literature. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010601
Diaminodiphenylmethane (DDM): frequency of sensitization, clinical relevance and concomitant positive reactions. Contact dermatitis 20010501
Resolution of isomers of sorbitolparaben esters by chromatographic and electrophoretic techniques. Journal of chromatography. B, Biomedical sciences and applications 20010305
The first example of a paraben-dependent antibody to an Rh protein. Transfusion 20010301
Determination of ethyl-p-hydroxybenzoate in sow pancreatic juice by reversed-phase high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications 20010225
Analytical control of a pharmaceutical formulation of sodium picosulfate by capillary zone electrophoresis. Journal of chromatography. B, Biomedical sciences and applications 20010210
A new application for the Antoine equation in formulation development. International journal of pharmaceutics 20010201
Sorption of parabens by fluoropolymer or fluoropolymer laminated flexible tubing. PDA journal of pharmaceutical science and technology 20010101
Determination of methylparaben, propylparaben and chlorpromazine in chlorpromazine hydrochloride oral solution by high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications 19980410
Symposium - the city: a viable environment for the elderly? Phase III: Planning and delivery of health services. On Lok Day Health Center; a case study. The Gerontologist 19760201
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