(βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid
| Title | Journal |
|---|---|
| Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels in Primary Cultured Mouse and Rat Hepatocytes. | The Journal of pharmacology and experimental therapeutics 20160801 |
| Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice. | Toxicology 20160217 |
| Pravastatin and Sarpogrelate Synergistically Ameliorate Atherosclerosis in LDLr-Knockout Mice. | PloS one 20160101 |
| Statins alter the hepatobiliary transport of unconjugated and conjugated bilirubin in sandwich-cultured rat hepatocytes. | Toxicology in vitro : an international journal published in association with BIBRA 20140901 |
| Simvastatin-lnduced nocturnal leg pain disappears with pravastatin substitution. | Srpski arhiv za celokupno lekarstvo 20130101 |
| Influence of SLCO1B1 polymorphisms on the drug-drug interaction between darunavir/ritonavir and pravastatin. | Journal of clinical pharmacology 20121101 |
| The role of statin therapy in the prevention of atrial fibrillation: a meta-analysis of randomized controlled trials. | British journal of clinical pharmacology 20121101 |
| Statin use and the risk of Clostridium difficile in academic medical centres. | Gut 20121101 |
| Anti-cancer characteristics of mevinolin against three different solid tumor cell lines was not solely p53-dependent. | Journal of enzyme inhibition and medicinal chemistry 20121001 |
| Statin myopathy: a lipid clinic experience on the tolerability of statin rechallenge. | Cardiovascular therapeutics 20121001 |
| Atorvastatin and pitavastatin enhance lipoprotein lipase production in L6 skeletal muscle cells through activation of adenosine monophosphate-activated protein kinase. | Metabolism: clinical and experimental 20121001 |
| Physiologically based modeling of pravastatin transporter-mediated hepatobiliary disposition and drug-drug interactions. | Pharmaceutical research 20121001 |
| Development and validation of a simple and fast HPLC method for determination of lovastatin, pravastatin and simvastatin. | Journal of chromatographic science 20121001 |
| Pravastatin normalizes ET-1-induced contraction in the aorta of type 2 diabetic OLETF rats by suppressing the KSR1/ERK complex. | American journal of physiology. Heart and circulatory physiology 20121001 |
| Pravastatin does not prevent antiphospholipid antibody-mediated changes in human first trimester trophoblast function. | Human reproduction (Oxford, England) 20121001 |
| Association of cholesteryl ester transfer protein mass with peripheral leukocyte count following statin therapy: a pilot study. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20121001 |
| Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on arterial compliance and distensibility in patients with mild-to-moderate chronic kidney disease. | Clinical nephrology 20121001 |
| Effects of rosuvastatin versus pravastatin on low-density lipoprotein diameter in HIV-1-infected patients receiving ritonavir-boosted protease inhibitor. | AIDS (London, England) 20120910 |
| Simvastatin evokes an unpredicted inhibition of β-adrenoceptor-mediated vasodilatation in porcine coronary artery. | European journal of pharmacology 20120905 |
| Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice. | Molecular pharmaceutics 20120904 |
| Pravastatin-induced proangiogenic effects depend upon extracellular FGF-2. | Journal of cellular and molecular medicine 20120901 |
| Pravastatin reverses the membrane cholesterol reorganization induced by myocardial infarction within lipid rafts in CD14(+)/CD16(-) circulating monocytes. | Biochimica et biophysica acta 20120901 |
| Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study. | European heart journal 20120901 |
| Importance of assessing the effect of statins on the function of high- density lipoproteins on coronary plaque. | Cardiovascular & hematological disorders drug targets 20120901 |
| Role of genetic factors in statins side-effects. | Cardiovascular & hematological disorders drug targets 20120901 |
| Use of mechanistic modeling to assess interindividual variability and interspecies differences in active uptake in human and rat hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20120901 |
| Genetic variation in galectin-3 gene associates with cognitive function at old age. | Neurobiology of aging 20120901 |
| Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β. | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20120901 |
| Impacts of estimated glomerular filtration rate on coronary atherosclerosis and plaque composition before and during statin therapy in patients with normal to mild renal dysfunction: subanalysis of the TRUTH study. | Nephrology (Carlton, Vic.) 20120901 |
| The safety and effectiveness of statins as treatment for HIV-dyslipidemia: the evidence so far and the future challenges. | Expert opinion on pharmacotherapy 20120901 |
| Statins and new-onset diabetes: a retrospective longitudinal cohort study. | Clinical therapeutics 20120901 |
| Can statins reduce the inflammatory response associated with preterm birth in an animal model? | American journal of obstetrics and gynecology 20120901 |
| Prediction of the in vivo OATP1B1-mediated drug-drug interaction potential of an investigational drug against a range of statins. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120830 |
| Chronic cyclosporine nephropathy is characterized by excessive autophagosome formation and decreased autophagic clearance. | Transplantation 20120815 |
| Clinical response to statins: mechanism(s) of variable activity and adverse effects. | Annals of medicine 20120801 |
| Poor maternal nutrition programmes a pro-atherosclerotic phenotype in ApoE-/- mice. | Clinical science (London, England : 1979) 20120801 |
| Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level. | Metabolism: clinical and experimental 20120801 |
| Pravastatin and simvastatin improves acetylsalicylic acid-mediated in vitro blood platelet inhibition. | European journal of clinical investigation 20120801 |
| Elevated concentration of placental growth factor (PlGF) and long term risk in patients with acute coronary syndrome in the PROVE IT-TIMI 22 trial. | Journal of thrombosis and thrombolysis 20120801 |
| Dyslipidemia and its therapeutic challenges in renal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120801 |
| Coenzyme Q10 reverses mitochondrial dysfunction in atorvastatin-treated mice and increases exercise endurance. | Journal of applied physiology (Bethesda, Md. : 1985) 20120801 |
| Involvement of cholesterol efflux pathway in the control of cardiomyocytes cholesterol homeostasis. | Journal of molecular and cellular cardiology 20120801 |
| Association of the low-density lipoprotein cholesterol/high-density lipoprotein cholesterol ratio and body mass index with coronary plaque regression. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20120801 |
| Erythrocyte-mediated delivery of pravastatin: in vitro study of effect of hypotonic lysis on biochemical parameters and loading efficiency. | Archives of pharmacal research 20120801 |
| Prospective, randomized, single-blind comparison of effects of 6 months' treatment with atorvastatin versus pravastatin on leptin and angiogenic factors in patients with coronary artery disease. | Heart and vessels 20120701 |
| Modulation of h(2)s metabolism by statins: a new aspect of cardiovascular pharmacology. | Antioxidants & redox signaling 20120701 |
| Comparative efficacy and safety of fenofibrate/pravastatin plus ezetimibe triple therapy and simvastatin/ezetimibe dual therapy in type 2 diabetic patients with mixed hyperlipidaemia and cardiovascular disease. | Diabetes & vascular disease research 20120701 |
| Randomized comparison of pitavastatin and pravastatin treatment on the reduction of urinary albumin in patients with type 2 diabetic nephropathy. | Diabetes, obesity & metabolism 20120701 |
| Effects of bile salts on gastrointestinal absorption of pravastatin. | Journal of pharmaceutical sciences 20120701 |
| Mediating effects of aryl-hydrocarbon receptor and RhoA in altering brain vascular integrity: the therapeutic potential of statins. | The American journal of pathology 20120701 |
| Cholesterol level goal attainment with statins: clinical management guideline recommendations versus management in actual clinical practice. | Pharmacotherapy 20120701 |
| ACP Journal Club. Review: Perioperative statins reduce perioperative MI and AF in statin-naïve patients. | Annals of internal medicine 20120619 |
| Role of non-high-density lipoprotein cholesterol in predicting cerebrovascular events in patients following myocardial infarction. | The American journal of cardiology 20120615 |
| Cost-effectiveness of extended-release niacin/laropiprant added to a stable simvastatin dose in secondary prevention patients not at cholesterol goal in Germany. | The European journal of health economics : HEPAC : health economics in prevention and care 20120601 |
| Blood pressure control status and effects of pravastatin on cardiovascular events occurrence in patients with dyslipidaemia. | Journal of human hypertension 20120601 |
| Potential role of statins on wound healing: review of the literature. | International wound journal 20120601 |
| Patient socioeconomic determinants for the choice of the cheapest molecule within a cluster: evidence from Belgian prescription data. | The European journal of health economics : HEPAC : health economics in prevention and care 20120601 |
| Pravastatin normalizes endothelium-derived contracting factor-mediated response via suppression of Rho-kinase signalling in mesenteric artery from aged type 2 diabetic rat. | Acta physiologica (Oxford, England) 20120601 |
| Molecular pathways regulating macrophage polarization: implications for atherosclerosis. | Current atherosclerosis reports 20120601 |
| Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress. | Cardiovascular research 20120601 |
| A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter. | American journal of physiology. Cell physiology 20120601 |
| The effect of low-dose pravastatin in metabolic syndrome for primary prevention of cardiovascular disease in Japan: a post hoc analysis of the MEGA study. | Journal of cardiovascular pharmacology and therapeutics 20120601 |
| [Effects of Chinese herbal medicine Shoushen Granule on telomere length and telomerase activity of peripheral white blood cells and vascular cells in rats with atherosclerosis]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120601 |
| Effects of pravastatin or 12/15 lipoxygenase pathway inhibitors on indices of diabetic nephropathy in an experimental model of diabetic renal disease. | Saudi medical journal 20120601 |
| Effect of Huxin Formula on reverse cholesterol transport in ApoE-gene knockout mice. | Chinese journal of integrative medicine 20120601 |
| The evaluation of analgesic effects of simvastatin, pravastatin and atorvastatin in hot plate test. | European review for medical and pharmacological sciences 20120601 |
| Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
| The differential effects of statins on the metastatic behaviour of prostate cancer. | British journal of cancer 20120508 |
| Pravastatin inhibits farnesol production in Candida albicans and improves survival in a mouse model of systemic candidiasis. | Medical mycology 20120501 |
| Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment. | British journal of clinical pharmacology 20120501 |
| EPR studies on hydroxyl radical-scavenging activities of pravastatin and fluvastatin. | Molecular and cellular biochemistry 20120501 |
| Using expression data for quantification of active processes in physiologically based pharmacokinetic modeling. | Drug metabolism and disposition: the biological fate of chemicals 20120501 |
| Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). | Diabetologia 20120501 |
| Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats. | American journal of hypertension 20120501 |
| Mechanistic pharmacokinetic modeling for the prediction of transporter-mediated disposition in humans from sandwich culture human hepatocyte data. | Drug metabolism and disposition: the biological fate of chemicals 20120501 |
| Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a). | Journal of lipid research 20120501 |
| Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells. | Clinical and experimental immunology 20120501 |
| Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain. | Critical reviews in toxicology 20120501 |
| Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives. | Pharmacogenomics 20120501 |
| Pravastatin and fenofibrate in combination (Pravafenix(®)) for the treatment of high-risk patients with mixed hyperlipidemia. | Expert review of cardiovascular therapy 20120501 |
| Pravastatin attenuates noise-induced cochlear injury in mice. | Neuroscience 20120419 |
| RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo. | Gene therapy 20120401 |
| Simultaneous assessment of uptake and metabolism in rat hepatocytes: a comprehensive mechanistic model. | The Journal of pharmacology and experimental therapeutics 20120401 |
| The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways. | Diabetologia 20120401 |
| Complete mitochondrial genome of compactin-producing fungus Penicillium solitum and comparative analysis of Trichocomaceae mitochondrial genomes. | FEMS microbiology letters 20120401 |
| Direct to consumer Internet advertising of statins: an assessment of safety. | Pharmacoepidemiology and drug safety 20120401 |
| Diabetes-specific nutrition algorithm: a transcultural program to optimize diabetes and prediabetes care. | Current diabetes reports 20120401 |
| Mechanisms involved in cardioprotective effects of pravastatin administered during reoxygenation in human myocardium in vitro. | Anesthesiology 20120401 |
| Safety of a fixed-dose combination of fenofibrate/pravastatin 160 mg/40 mg in patients with mixed hyperlipidaemia: a pooled analysis from a database of clinical trials. | Clinical drug investigation 20120401 |
| Targeting HDL-cholesterol to reduce residual cardiovascular risk. | Current opinion in lipidology 20120401 |
| Is statin-associated cognitive impairment clinically relevant? A narrative review and clinical recommendations. | The Annals of pharmacotherapy 20120401 |
| The Effects of Combined Treatment with an HMG-CoA Reductase Inhibitor and PPARγ Agonist on the Activation of Rat Pancreatic Stellate Cells. | Gut and liver 20120401 |
| Effects of green tea or Sasa quelpaertensis bamboo leaves on plasma and liver lipids, erythrocyte Na efflux, and platelet aggregation in ovariectomized rats. | Nutrition research and practice 20120401 |
| Preventing a Cardiovascular Disease Epidemic among Indigenous Populations through Lifestyle Changes. | International journal of preventive medicine 20120401 |
| Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome. | Lancet (London, England) 20120310 |
| Pitavastatin: a review of its use in the management of hypercholesterolaemia or mixed dyslipidaemia. | Drugs 20120305 |
| Development of a model for prediction of coronary atherosclerotic regression: evaluation of high-density lipoprotein cholesterol level and peripheral blood monocyte count. | Heart and vessels 20120301 |
| In vitro evaluation of phototoxic properties of proton pump inhibitors, H2-receptor antagonists and statins. | Acta dermato-venereologica 20120301 |
| Effect of lipophilicity on the bioavailability of drugs after percutaneous administration by dissolving microneedles. | Journal of pharmaceutical sciences 20120301 |
| In vivo biliary clearance should be predicted by intrinsic biliary clearance in sandwich-cultured hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20120301 |
| Subclinical thyroid dysfunction and the risk of heart failure in older persons at high cardiovascular risk. | The Journal of clinical endocrinology and metabolism 20120301 |
| Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis. | European heart journal 20120301 |
| Effect of dalcetrapib plus pravastatin on lipoprotein metabolism and high-density lipoprotein composition and function in dyslipidemic patients: results of a phase IIb dose-ranging study. | American heart journal 20120301 |
| Amino acid and vitamin supplementation improved health conditions in elderly participants. | Journal of clinical biochemistry and nutrition 20120301 |
| Genome-wide association and functional follow-up reveals new loci for kidney function. | PLoS genetics 20120301 |
| Effects of 4-week administration of simvastatin in different doses on heart rate and blood pressure after metoprolol injection in normocholesterolaemic and normotensive rats. | Archives of medical science : AMS 20120227 |
| The impact of statin therapy on long-term cardiovascular outcomes in an outpatient cardiology practice. | Archives of medical science : AMS 20120227 |
| Reduction in atherosclerotic events: a retrospective study in an outpatient cardiology practice. | Archives of medical science : AMS 20120227 |
| Determination of pravastatin and pravastatin lactone in rat plasma and urine using UHPLC-MS/MS and microextraction by packed sorbent. | Talanta 20120215 |
| Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. | Nature cell biology 20120212 |
| Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus. | Journal of medicinal chemistry 20120209 |
| Pravastatin for thioacetamide-induced hepatic failure and encephalopathy. | European journal of clinical investigation 20120201 |
| Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial. | European heart journal 20120201 |
| The effects of a single nucleotide polymorphism in SLCO1B1 on the pharmacodynamics of pravastatin. | British journal of clinical pharmacology 20120201 |
| In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions. | Pharmaceutical research 20120201 |
| Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis. | QJM : monthly journal of the Association of Physicians 20120201 |
| Pravastatin inhibits C-reactive protein generation induced by fibrinogen, fibrin and FDP in isolated rat vascular smooth muscle cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120201 |
| Hypermethylation at loci sensitive to the prenatal environment is associated with increased incidence of myocardial infarction. | International journal of epidemiology 20120201 |
| A review of the rationale for additional therapeutic interventions to attain lower LDL-C when statin therapy is not enough. | Current atherosclerosis reports 20120201 |
| Explication of interactions between HMGCR isoform 2 and various statins through In silico modeling and docking. | Computers in biology and medicine 20120201 |
| Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly. | Atherosclerosis 20120201 |
| KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly. | Atherosclerosis 20120201 |
| Identification and characterization of Penicillium citrinum VeA and LaeA as global regulators for ML-236B production. | Current genetics 20120201 |
| HMG-CoA reductase inhibitors (statins) reduce hypertrophic scar formation in a rabbit ear wounding model. | Plastic and reconstructive surgery 20120201 |
| Statin treatment for coronary artery plaque composition based on intravascular ultrasound radiofrequency data analysis. | American heart journal 20120201 |
| Pravastatin reduces steroid-induced osteonecrosis of the femoral head in SHRSP rats. | Acta orthopaedica 20120201 |
| Plant sterols and cardiovascular disease: a systematic review and meta-analysis. | European heart journal 20120201 |
| Statin therapy in the elderly: might there be uncertainty in the majority? | European journal of preventive cardiology 20120201 |
| Statin treatment depresses the fetal defence to acute hypoxia via increasing nitric oxide bioavailability. | The Journal of physiology 20120115 |
| [Specific considerations on the prescription and therapeutic interchange of statins]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20120101 |
| Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients: Effects of Antiretroviral Therapy and Adipose Tissue Distribution. | International journal of vascular medicine 20120101 |
| Understanding postprandial inflammation and its relationship to lifestyle behaviour and metabolic diseases. | International journal of vascular medicine 20120101 |
| The chylomicron: relationship to atherosclerosis. | International journal of vascular medicine 20120101 |
| Effect of intensive lipid-lowering therapy with rosuvastatin on progression of carotid intima-media thickness in Japanese patients: Justification for Atherosclerosis Regression Treatment (JART) study. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Galectin-3 and the development of heart failure after acute coronary syndrome: pilot experience from PROVE IT-TIMI 22. | Clinical chemistry 20120101 |
| Usefulness of LDL-C-related parameters to predict cardiovascular risk and effect of pravastatin in mild-to-moderate hypercholesterolemia. | Journal of atherosclerosis and thrombosis 20120101 |
| The long-term effect of statins on the risk of new-onset diabetes mellitus in elderly Taiwanese patients with hypertension and dyslipidaemia: a retrospective longitudinal cohort study. | Drugs & aging 20120101 |
| Bilayered transmucosal drug delivery system of pravastatin sodium: statistical optimization, in vitro, ex vivo, in vivo and stability assessment. | Drug delivery 20120101 |
| Control strategy on hypertension in chinese medicine. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| The pathophysiology of HIV-/HAART-related metabolic syndrome leading to cardiovascular disorders: the emerging role of adipokines. | Experimental diabetes research 20120101 |
| Adverse event profiles of 5-fluorouracil and capecitabine: data mining of the public version of the FDA Adverse Event Reporting System, AERS, and reproducibility of clinical observations. | International journal of medical sciences 20120101 |
| Atorvastatin treatment is effective when used in combination with mefloquine in an experimental cerebral malaria murine model. | Malaria journal 20120101 |
| Quantile-specific penetrance of genes affecting lipoproteins, adiposity and height. | PloS one 20120101 |
| Cholesterol-lowering drugs and incident open-angle glaucoma: a population-based cohort study. | PloS one 20120101 |
| Effects of bile-acid-binding resin (colestimide) on blood glucose and visceral fat in Japanese patients with type 2 diabetes mellitus and hypercholesterolemia: an open-label, randomized, case-control, crossover study. | Journal of diabetes and its complications 20120101 |
| Genetic interactions between chromosomes 11 and 18 contribute to airway hyperresponsiveness in mice. | PloS one 20120101 |
| Lipid disorders in elderly hypertensive patients. | International journal of hypertension 20120101 |
| The differential effect of statins on oxidative stress and endothelial function: atorvastatin versus pravastatin. | Journal of clinical lipidology 20120101 |
| Evidence-based prediction of statin use with lipid-panel data from the National Health and Nutrition Examination Survey. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20120101 |
| Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles. | International journal of nanomedicine 20120101 |
| Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy. | PloS one 20120101 |
| Proteomic analysis of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis. | PloS one 20120101 |
| Preventive pharmacotherapy in type 2 diabetes mellitus. | Indian journal of endocrinology and metabolism 20120101 |
| Managing atrial fibrillation in the elderly: critical appraisal of dronedarone. | Clinical interventions in aging 20120101 |
| Effects of sterol regulatory element-binding protein (SREBP) in chickens. | Lipids in health and disease 20120101 |
| Niacin extended-release/simvastatin combination therapy produces larger favorable changes in high-density lipoprotein particles than atorvastatin monotherapy. | Vascular health and risk management 20120101 |
| Antihyperlipidemic activity of Salacia chinensis root extracts in triton-induced and atherogenic diet-induced hyperlipidemic rats. | Indian journal of pharmacology 20120101 |
| Treatment Options in Cushing's Disease. | Clinical Medicine Insights. Oncology 20120101 |
| Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events. | ClinicoEconomics and outcomes research : CEOR 20120101 |
| Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models. | Cancer cell international 20120101 |
| An anti-PCSK9 antibody reduces LDL-cholesterol on top of a statin and suppresses hepatocyte SREBP-regulated genes. | International journal of biological sciences 20120101 |
| The effect of statin therapy in stroke outcome: a double blind clinical trial. | International journal of preventive medicine 20120101 |
| Self-microemulsifying drug-delivery system for improved oral bioavailability of probucol: preparation and evaluation. | International journal of nanomedicine 20120101 |
| A Medicinal Herb Scutellaria lateriflora Inhibits PrP Replication in vitro and Delays the Onset of Prion Disease in Mice. | Frontiers in psychiatry 20120101 |
| Central versus peripheral cardiovascular risk in metabolic syndrome. | Frontiers in physiology 20120101 |
| The relation between serum lipids and lutein and zeaxanthin in the serum and retina: results from cross-sectional, case-control and case study designs. | Lipids in health and disease 20120101 |
| Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. | PloS one 20120101 |
| NMR evaluation of total statin content and HMG-CoA reductase inhibition in red yeast rice (Monascus spp.) food supplements. | Chinese medicine 20120101 |
| Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease. | Clinical Medicine Insights. Cardiology 20120101 |
| Improved preservation of residual beta cell function by atorvastatin in patients with recent onset type 1 diabetes and high CRP levels (DIATOR trial). | PloS one 20120101 |
| Smoking and idiopathic pulmonary fibrosis. | Pulmonary medicine 20120101 |
| Nebivolol: impact on cardiac and endothelial function and clinical utility. | Vascular health and risk management 20120101 |
| LIPITENSION: Interplay between dyslipidemia and hypertension. | Indian journal of endocrinology and metabolism 20120101 |
| Achieving secondary prevention low-density lipoprotein particle concentration goals using lipoprotein cholesterol-based data. | PloS one 20120101 |
| Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics. | International journal of Alzheimer's disease 20120101 |
| Pro-inflammatory S100A8 and S100A9 proteins: self-assembly into multifunctional native and amyloid complexes. | International journal of molecular sciences 20120101 |
| Effect of a dipeptidyl peptidase-IV inhibitor, des-fluoro-sitagliptin, on neointimal formation after balloon injury in rats. | PloS one 20120101 |
| Sinusoidal endothelial dysfunction precedes inflammation and fibrosis in a model of NAFLD. | PloS one 20120101 |
| Efficacy of short-term high-dose statin in preventing contrast-induced nephropathy: a meta-analysis of seven randomized controlled trials. | PloS one 20120101 |
| A comparative effect of atorvastatin with other statins in patients of hyperlipidemia. | Indian journal of pharmacology 20120101 |
| Emerging drug combinations to optimize renovascular protection and blood pressure goals. | International journal of nephrology and renovascular disease 20120101 |
| Recurrent acute pancreatitis probably induced by rosuvastatin therapy: a case report. | Case reports in medicine 20120101 |
| The effect of rosuvastatin in a murine model of influenza A infection. | PloS one 20120101 |
| Nitric oxide manipulation: a therapeutic target for peripheral arterial disease? | Cardiology research and practice 20120101 |
| Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α. | Journal of neuroinflammation 20120101 |
| Statins accelerate the onset of collagen type II-induced arthritis in mice. | Arthritis research & therapy 20120101 |
| Mixed dyslipidemias in primary care patients in France. | Vascular health and risk management 20120101 |
| A systematic review of xuezhikang, an extract from red yeast rice, for coronary heart disease complicated by dyslipidemia. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| The effect of storage temperature and time on the concentrations of bovine serum amyloid a and its mammary associated isoform. | Veterinary medicine international 20120101 |
| Public health concerns for anti-obesity medicines imported for personal use through the internet: a cross-sectional study. | BMJ open 20120101 |
| Statin therapy decreases serum levels of high-sensitivity C-reactive protein and tumor necrosis factor-α in HIV-infected patients treated with ritonavir-boosted protease inhibitors. | HIV clinical trials 20120101 |
| Discontinuation of statin therapy in older people: does a cancer diagnosis make a difference? An observational cohort study using data linkage. | BMJ open 20120101 |
| Do statins improve outcomes in patients with asthma on inhaled corticosteroid therapy? A retrospective cohort analysis. | BMJ open 20120101 |
| Controlled release and angiotensin-converting enzyme inhibition properties of an antihypertensive drug based on a perindopril erbumine-layered double hydroxide nanocomposite. | International journal of nanomedicine 20120101 |
| Efficacy, safety and tolerability of ongoing statin plus ezetimibe versus doubling the ongoing statin dose in hypercholesterolemic Taiwanese patients: an open-label, randomized clinical trial. | BMC research notes 20120101 |
| Ezetimibe improves endothelial function and inhibits Rho-kinase activity associated with inhibition of cholesterol absorption in humans. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Diverse spectrum of presentation of coronary slow flow phenomenon: a concise review of the literature. | Cardiology research and practice 20120101 |
| Sense and nonsense in metabolic control of reproduction. | Frontiers in endocrinology 20120101 |
| Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levels. | Current gerontology and geriatrics research 20120101 |
| Lipid disorders in uremia and dialysis. | Contributions to nephrology 20120101 |
| The effectiveness and cost effectiveness of dark chocolate consumption as prevention therapy in people at high risk of cardiovascular disease: best case scenario analysis using a Markov model. | BMJ (Clinical research ed.) 20120101 |
| LDL-apheresis: technical and clinical aspects. | TheScientificWorldJournal 20120101 |
| Double-dose pravastatin versus add-on ezetimibe with low-dose pravastatin - effects on LDL cholesterol, cholesterol absorption, and cholesterol synthesis in Japanese patients with hypercholesterolemia (PEAS study). | Journal of atherosclerosis and thrombosis 20120101 |
| Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases. | Vascular health and risk management 20120101 |
| Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice. | PloS one 20120101 |
| Genome-wide study of gene variants associated with differential cardiovascular event reduction by pravastatin therapy. | PloS one 20120101 |
| Practical application of cytochrome P450. | Biological & pharmaceutical bulletin 20120101 |
| [Effects of acidification and alkalinization agents on statins-induced muscle toxicity]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101 |
| Genetics Techniques for Thermococcus kodakarensis. | Frontiers in microbiology 20120101 |
| Metabolic disorders and steatosis in patients with chronic hepatitis C: metabolic strategies for antiviral treatments. | International journal of hepatology 20120101 |
| Biomarkers of chronic inflammatory state in uremia and cardiovascular disease. | International journal of inflammation 20120101 |
| Selected statins produce rapid spinal motor neuron loss in vitro. | BMC musculoskeletal disorders 20120101 |
| Economic evaluation of statins in high-risk patients treated for primary and secondary prevention of cardiovascular disease in Greece. | ClinicoEconomics and outcomes research : CEOR 20120101 |
| Atorvastatin and simvastatin, but not pravastatin, up-regulate LPS-induced MMP-9 expression in macrophages by regulating phosphorylation of ERK and CREB. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101 |
| Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies. | PloS one 20120101 |
| [Equivalence studies of pravastatin original and generic drugs by dissolution test]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101 |
| Effect of pravastatin on endothelial function and endothelial progenitor cells in healthy postmenopausal women. | Clinical and experimental obstetrics & gynecology 20120101 |
| Pravastatin-induced improvement in coronary reactivity and circulating ATP and ADP levels in young adults with type 1 diabetes. | Frontiers in physiology 20120101 |
| Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis. | PloS one 20120101 |
| A survey of the FDA's AERS database regarding muscle and tendon adverse events linked to the statin drug class. | PloS one 20120101 |
| Adherence to preferable behavior for lipid control by high-risk dyslipidemic Japanese patients under pravastatin treatment: the APPROACH-J study. | Journal of atherosclerosis and thrombosis 20120101 |
| Ovariectomized mouse uterotrophic assay of 36 chemicals. | The Journal of toxicological sciences 20120101 |
| Angiotensin converting enzyme inhibitor and HMG-CoA reductase inhibitor as adjunct treatment for persons with HIV infection: a feasibility randomized trial. | PloS one 20120101 |
| Effects of pravastatin on the pharmacokinetic parameters of nimodipine after oral and intravenous administration in rats: possible role of CYP3A4 inhibition by pravastatin. | Indian journal of pharmacology 20120101 |
| Editorial on management of diabetes mellitus with coronary artery disease. | Archives of medical science : AMS 20111231 |
| Hypotensive effect of atorvastatin in hypertensive patients: the association among flow-mediated dilation, oxidative stress and endothelial dysfunction. | Archives of medical science : AMS 20111231 |
| IMproving the imPlemEntation of cuRrent guidelines for the mAnagement of major coronary hearT disease rIsk factors by multifactorial interVEntion. The IMPERATIVE renal analysis. | Archives of medical science : AMS 20111231 |
| Lipids, blood pressure, kidney - what was new in 2011? | Archives of medical science : AMS 20111231 |
| Chemical inhibitors suggest endophytic fungal paclitaxel is derived from both mevalonate and non-mevalonate-like pathways. | Journal of natural products 20111227 |
| Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: a randomised controlled trial. | Lancet (London, England) 20111210 |
| Incorporation of economic evidence in the Dutch guideline 'cardiovascular risk management'. | Journal of evaluation in clinical practice 20111201 |
| High-density lipoprotein cholesterol as a predictor of clinical outcomes in patients achieving low-density lipoprotein cholesterol targets with statins after percutaneous coronary intervention. | Heart (British Cardiac Society) 20111201 |
| Opposite effects of pravastatin and atorvastatin on insulin sensitivity in the rat: role of vitamin D metabolites. | Atherosclerosis 20111201 |
| Familial hypercholesterolemia: present and future management. | Current cardiology reports 20111201 |
| Is inflammation the cause of pre-eclampsia? | Biochemical Society transactions 20111201 |
| Fatal rhabdomyolysis in a patient with liver cirrhosis after switching from simvastatin to fluvastatin. | Journal of Korean medical science 20111201 |
| HMG-CoA reductase inhibitor (Statin) therapy and coronary atherosclerosis in Japanese subjects: role of high-density lipoprotein cholesterol. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20111201 |
| The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes. | International journal of epidemiology 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins. | Oncotarget 20111201 |
| [Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study]. | Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20111201 |
| What are the Evidence Based Public Health Interventions for Prevention and Control of NCDs in Relation to India? | Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine 20111201 |
| Therapeutic interventions targeting Beta amyloid pathogenesis in an aging dog model. | Current neuropharmacology 20111201 |
| Cost-effectiveness of the use of low- and high-potency statins in people at low cardiovascular risk. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20111108 |
| Modification of hepatic iron metabolism induced by pravastatin during obstructive cholestasis in rats. | Life sciences 20111107 |
| Low-dosage statins reduce choroidal damage in hypercholesterolemic rabbits. | Acta ophthalmologica 20111101 |
| Acute simvastatin increases endothelial nitric oxide synthase phosphorylation via AMP-activated protein kinase and reduces contractility of isolated rat mesenteric resistance arteries. | Clinical science (London, England : 1979) 20111101 |
| Effect of pravastatin on the frequency of ventilator-associated pneumonia and on intensive care unit mortality: open-label, randomized study. | Critical care medicine 20111101 |
| The neuroprotective effect of two statins: simvastatin and pravastatin on a streptozotocin-induced model of Alzheimer's disease in rats. | Journal of neural transmission (Vienna, Austria : 1996) 20111101 |
| Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein. | Atherosclerosis 20111101 |
| Differential effect of statins on diabetic nephropathy in db/db mice. | International journal of molecular medicine 20111101 |
| Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma. | Clinical endocrinology 20111101 |
| Acetoacetyl-CoA thiolase regulates the mevalonate pathway during abiotic stress adaptation. | Journal of experimental botany 20111101 |
| Long-term safety and efficacy of fenofibrate/pravastatin combination therapy in high risk patients with mixed hyperlipidemia not controlled by pravastatin monotherapy. | Current medical research and opinion 20111101 |
| Efficient bioconversion of compactin to pravastatin by the quinoline-degrading microorganism Pseudonocardia carboxydivorans isolated from petroleum-contaminated soil. | Bioresource technology 20111101 |
| Statins in preventing ventilator-associated pneumonia and death: still only a hope*. | Critical care medicine 20111101 |
| A cost-benefit analysis of lipid standardization in the United States. | Preventing chronic disease 20111101 |
| Apolipoprotein B100 is a better treatment target than calculated LDL and non-HDL cholesterol in statin-treated patients. | Annals of clinical biochemistry 20111101 |
| Statin therapy attenuates growth and malignant potential of human esophageal adenocarcinoma cells. | The Journal of thoracic and cardiovascular surgery 20111101 |
| Statin therapy for the prevention of atrial fibrillation: a meta-analysis of randomized controlled trials. | Pharmacotherapy 20111101 |
| Modifiers of symptomatic embolic risk in infective endocarditis. | Mayo Clinic proceedings 20111101 |
| Lipid lowering drugs and gallstones: a therapeutic option? | Current pharmaceutical design 20111101 |
| Gender differences, polypharmacy, and potential pharmacological interactions in the elderly. | Clinics (Sao Paulo, Brazil) 20111101 |
| Pitavastatin: novel effects on lipid parameters. | Atherosclerosis. Supplements 20111101 |
| The effects of statin and niacin on plaque stability, plaque regression, inflammation and oxidative stress in patients with mild to moderate coronary artery stenosis. | Korean circulation journal 20111101 |
| Role of lipid rafts in porcine reproductive and respiratory syndrome virus infection in MARC-145 cells. | Biochemical and biophysical research communications 20111028 |
| High-sensitivity C-reactive protein levels do not decrease with the use of statins in all persons with HIV infection. | AIDS (London, England) 20111023 |
| Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters. | Molecular pharmaceutics 20111003 |
| NOX1, 2, 4, 5: counting out oxidative stress. | British journal of pharmacology 20111001 |
| Pravastatin modulates liver bile acid and cholesterol homeostasis in rats with chronic cholestasis. | Journal of gastroenterology and hepatology 20111001 |
| Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk. | Arteriosclerosis, thrombosis, and vascular biology 20111001 |
| The discovery of LOX-1, its ligands and clinical significance. | Cardiovascular drugs and therapy 20111001 |
| Statins inhibit chemotactic interaction between CCL20 and CCR6 in vitro: possible relevance to psoriasis treatment. | Experimental dermatology 20111001 |
| Genetic testing for early detection of individuals at risk of coronary heart disease and monitoring response to therapy: challenges and promises. | Current atherosclerosis reports 20111001 |
| Identification of the rate-determining process in the hepatic clearance of atorvastatin in a clinical cassette microdosing study. | Clinical pharmacology and therapeutics 20111001 |
| Role of complement component C1q in the onset of preeclampsia in mice. | Hypertension (Dallas, Tex. : 1979) 20111001 |
| Effects of statins on cholestasis: good, bad or indifferent? | Journal of gastroenterology and hepatology 20111001 |
| Effects of pravastatin on mediators of vascular function in a mouse model of soluble Fms-like tyrosine kinase-1-induced preeclampsia. | American journal of obstetrics and gynecology 20111001 |
| Smaller Mean LDL Particle Size and Higher Proportion of Small Dense LDL in Korean Type 2 Diabetic Patients. | Diabetes & metabolism journal 20111001 |
| Are patients undergoing treatment of hyperlipidaemia with statins the best candidates for early cardiac rehabilitation? | Archives of medical science : AMS 20111001 |
| Effectiveness and tolerability of ezetimibe co-administered with statins versus statin dose-doubling in high-risk patients with persistent hyperlipidemia: The EZE(STAT)2 trial. | Archives of medical science : AMS 20111001 |
| Safety and impact on cardiovascular events of long-term multifactorial treatment in patients with metabolic syndrome and abnormal liver function tests: a post hoc analysis of the randomised ATTEMPT study. | Archives of medical science : AMS 20111001 |
| Pravastatin reduces Marfan aortic dilation. | Circulation 20110913 |
| Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein. | Journal of pharmaceutical sciences 20110901 |
| Molecular mechanism of vasorelaxant and antiatherogenic effects of the statins in the human saphenous vein graft. | European journal of pharmacology 20110901 |
| Cardiac remodeling caused by transgenic overexpression of a corn Rac gene. | American journal of physiology. Heart and circulatory physiology 20110901 |
| Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20110901 |
| Low-dose pravastatin and age-related differences in risk factors for cardiovascular disease in hypercholesterolaemic Japanese: analysis of the management of elevated cholesterol in the primary prevention group of adult Japanese (MEGA study). | Drugs & aging 20110901 |
| Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3. | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20110901 |
| Neurotoxic effect of statins on mouse neuroblastoma NB2a cell line. | European review for medical and pharmacological sciences 20110901 |
| Comparison of clinical outcomes of hydrophilic and lipophilic statins in patients with acute myocardial infarction. | The Korean journal of internal medicine 20110901 |
| [Prediction of the pharmacokinetic drug-drug interaction of pravastatin and pitavastatin with cyclosporine by a digital liver model based on metabolism and transporter]. | Yao xue xue bao = Acta pharmaceutica Sinica 20110901 |
| Challenges in diagnosis of isolated central nervous system vasculitis. | Brain and behavior 20110901 |
| Graft-protective effects of the HMG-CoA reductase inhibitor pravastatin after lung transplantation--a propensity score analysis with 23 years of follow-up. | Transplantation 20110827 |
| HMG-CoA reductase inhibitor augments the serum total cholesterol-lowering effect of human adipose tissue-derived multilineage progenitor cells in hyperlipidemic homozygous Watanabe rabbits. | Biochemical and biophysical research communications 20110819 |
| Disturbed subjective sleep characteristics in adult patients with long-standing type 1 diabetes mellitus. | Diabetologia 20110801 |
| Long-term follow-up of statin treatment in a cohort of children with familial hypercholesterolemia: efficacy and tolerability. | Paediatric drugs 20110801 |
| Statins promote the growth of experimentally induced cerebral aneurysms in estrogen-deficient rats. | Stroke 20110801 |
| HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7. | Atherosclerosis 20110801 |
| The complex interplay between cholesterol and prostate malignancy. | The Urologic clinics of North America 20110801 |
| Lenalidomide in combination with dexamethasone induced rhabdomyolysis in a multiple myeloma patient treated with pravastatin. | International journal of hematology 20110801 |
| Rosuvastatin prevents proteinuria and renal inflammation in nitric oxide-deficient rats. | Clinics (Sao Paulo, Brazil) 20110801 |
| Effect of previous statin therapy in patients with acute coronary syndrome and percutaneous coronary intervention. | Korean circulation journal 20110801 |
| Comparison of different extraction methods for the determination of statin drugs in wastewater and river water by HPLC/Q-TOF-MS. | Talanta 20110715 |
| Data mining approach shows promise in detecting unexpected drug interactions. | JAMA 20110713 |
| Effect of pravastatin on cisplatin-induced nephrotoxicity in rats. | Human & experimental toxicology 20110701 |
| Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20110701 |
| The statin class of HMG-CoA reductase inhibitors demonstrate differential activation of the nuclear receptors PXR, CAR and FXR, as well as their downstream target genes. | Xenobiotica; the fate of foreign compounds in biological systems 20110701 |
| Ideal lipid profile and genes for an extended life span. | Current opinion in cardiology 20110701 |
| Pulmonary arterial hypertension and statins: an update. | Current opinion in cardiology 20110701 |
| Genomic markers to tailor treatments: waiting or initiating? | Human genetics 20110701 |
| HMG CoA reduction in patients with average cholesterol concentrations. | Clinical chemistry 20110701 |
| Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels. | Clinical pharmacology and therapeutics 20110701 |
| Topical anti-inflammatory effect of hypocholesterolaemic drugs. | The Journal of pharmacy and pharmacology 20110701 |
| Stroke management. | Annals of Indian Academy of Neurology 20110701 |
| Coronary atherosclerotic plaque rupture following thoracic trauma: an uncommon cause of angina and ventricular tachycardia ('torsade de pointes'). | Clinics (Sao Paulo, Brazil) 20110701 |
| New species in Aspergillus section Terrei. | Studies in mycology 20110630 |
| [Pharmaco-economic optimization of cholesterol-lowering treatment with statins]. | Medicina clinica 20110625 |
| Intravenous administration of pravastatin immediately after middle cerebral artery occlusion reduces cerebral oedema in spontaneously hypertensive rats. | European journal of pharmacology 20110625 |
| Effect of statins on cholesterol crystallization and atherosclerotic plaque stabilization. | The American journal of cardiology 20110615 |
| The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. | Lancet (London, England) 20110609 |
| Statins and prostate cancer diagnosis and grade in a veterans population. | Journal of the National Cancer Institute 20110608 |
| Effects of pravastatin and rosuvastatin on the generation of adiponectin in the visceral adipose tissue in patients with coronary artery disease. | Fundamental & clinical pharmacology 20110601 |
| Reimbursement of pharmaceuticals: reference pricing versus health technology assessment. | The European journal of health economics : HEPAC : health economics in prevention and care 20110601 |
| A population-based survey of Chronic REnal Disease In Turkey--the CREDIT study. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110601 |
| Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study. | Journal of human hypertension 20110601 |
| High-density lipoprotein (HDL) cholesterol: leveraging practice-based biobank cohorts to characterize clinical and genetic predictors of treatment outcome. | The pharmacogenomics journal 20110601 |
| Prognostic utility of neopterin and risk of heart failure hospitalization after an acute coronary syndrome. | European heart journal 20110601 |
| Role of intestinal cytochrome P450 (P450) in modulating the bioavailability of oral lovastatin: insights from studies on the intestinal epithelium-specific P450 reductase knockout mouse. | Drug metabolism and disposition: the biological fate of chemicals 20110601 |
| Prediction of the overall renal tubular secretion and hepatic clearance of anionic drugs and a renal drug-drug interaction involving organic anion transporter 3 in humans by in vitro uptake experiments. | Drug metabolism and disposition: the biological fate of chemicals 20110601 |
| Treatment with pravastatin attenuates progression of chronic pancreatitis in rat. | Laboratory investigation; a journal of technical methods and pathology 20110601 |
| Influence of non-steroidal anti-inflammatory drugs on organic anion transporting polypeptide (OATP) 1B1- and OATP1B3-mediated drug transport. | Drug metabolism and disposition: the biological fate of chemicals 20110601 |
| Secreted phospholipase A2, lipoprotein hydrolysis, and atherosclerosis: integration with lipidomics. | Analytical and bioanalytical chemistry 20110601 |
| Effects of statins on matrix metalloproteinases and their endogenous inhibitors in human endothelial cells. | Naunyn-Schmiedeberg's archives of pharmacology 20110601 |
| Decline in low-density lipoprotein cholesterol concentration: lipid-lowering drugs, diet, or physical activity? Evidence from the Whitehall II study. | Heart (British Cardiac Society) 20110601 |
| Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management. | European heart journal 20110601 |
| Design and in vitro performance evaluation of purified microparticles of pravastatin sodium for intestinal delivery. | AAPS PharmSciTech 20110601 |
| Assessment of adiponectin and the risk of recurrent cardiovascular events in patients presenting with an acute coronary syndrome: observations from the Pravastatin Or atorVastatin Evaluation and Infection Trial-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22). | American heart journal 20110601 |
| Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria:Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT). | American heart journal 20110601 |
| Effects of D-003 (10 mg/day) on bone mineral density of the lumbar spine and femoral neck in postmenopausal women: a randomized, double-blinded study. | The Korean journal of internal medicine 20110601 |
| The pathophysiology of chronic graft-versus-host disease: the unveiling of an enigma. | The Korean journal of hematology 20110601 |
| Antihyperlipidemic activities of Pleurotus ferulae on biochemical and histological function in hypercholesterolemic rats. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110601 |
| Statins, inflammation and kidney disease. | Nature reviews. Nephrology 20110531 |
| Cascade Screening for Familial Hypercholesterolemia (FH). | PLoS currents 20110523 |
| High-sensitivity C-reactive protein levels fall during statin therapy in HIV-infected patients receiving ritonavir-boosted protease inhibitors. | AIDS (London, England) 20110515 |
| Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells. | Cancer chemotherapy and pharmacology 20110501 |
| Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution. | Bioorganic & medicinal chemistry letters 20110501 |
| Host cholesterol synthesis contributes to growth of intracellular Toxoplasma gondii in macrophages. | The Journal of veterinary medical science 20110501 |
| Effect of statin therapy on disease progression in pediatric ADPKD: design and baseline characteristics of participants. | Contemporary clinical trials 20110501 |
| The incidence and risk factors for new onset atrial fibrillation in the PROSPER study. | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110501 |
| Statins downregulate K6a promoter activity: a possible therapeutic avenue for pachyonychia congenita. | The Journal of investigative dermatology 20110501 |
| Pravastatin therapy fails to suppress post-PCI inflammatory response measured by serum neopterin and CRP levels. | Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20110501 |
| Noninvasive assessment of atherosclerotic plaque progression in ApoE-/- mice using susceptibility gradient mapping. | Circulation. Cardiovascular imaging 20110501 |
| Benefit of intensive statin therapy in women: results from PROVE IT-TIMI 22. | Circulation. Cardiovascular quality and outcomes 20110501 |
| Treatment of indeterminate cell histiocytosis with pravastatin. | Journal of the American Academy of Dermatology 20110501 |
| Patent extension policy for paediatric indications: an evaluation of the impact within three drug classes in a state Medicaid programme. | Applied health economics and health policy 20110501 |
| The impact of pravastatin pre-treatment on periprocedural microcirculatory damage in patients undergoing percutaneous coronary intervention. | JACC. Cardiovascular interventions 20110501 |
| [Research on the effect of statins on insulin secretion from pancreatic islet in rats and its mechanisms]. | Zhonghua nei ke za zhi 20110501 |
| Effects of ezetimibe added to ongoing statin therapy on C-reactive protein levels in hypercholesterolemic patients. | Korean circulation journal 20110501 |
| Genetic variation in genes involved in folate and drug metabolism in a south Indian population. | Indian journal of human genetics 20110501 |
| Statin therapy blunts inflammatory activation and improves prognosis and left ventricular performance assessed by Tissue Doppler Imaging in subjects with chronic ischemic heart failure: results from the Daunia Heart Failure Registry. | Clinics (Sao Paulo, Brazil) 20110501 |
| Rosuvastatin and chronic hepatitis C. | Hepatitis monthly 20110501 |
| Elevated plasma platelet-activating factor acetylhydrolase activity and its relationship to the presence of coronary artery disease. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110501 |
| Sequential methods for random-effects meta-analysis. | Statistics in medicine 20110430 |
| Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | The Journal of biological chemistry 20110429 |
| Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures. | Journal of cellular and molecular medicine 20110401 |
| The combination of amlodipine and angiotensin receptor blocker or diuretics in high-risk hypertensive patients: rationale, design and baseline characteristics. | Journal of human hypertension 20110401 |
| An eight-week trial investigating the efficacy and tolerability of atorvastatin for children and adolescents with heterozygous familial hypercholesterolemia. | Pediatric cardiology 20110401 |
| Obesity is associated with fatal coronary heart disease independently of traditional risk factors and deprivation. | Heart (British Cardiac Society) 20110401 |
| Statins utilisation pattern: a retrospective evaluation in a tertiary care hospital in Thailand. | The International journal of pharmacy practice 20110401 |
| Treatment with pravastatin attenuates oxidative stress and protects osteoblast cell viability from indoxyl sulfate. | Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20110401 |
| Pravastatin activates PPARalpha/PPARgamma expression in the liver and gallbladder epithelium of hamsters. | Hepatobiliary & pancreatic diseases international : HBPD INT 20110401 |
| Strategies and practices in off-label marketing of pharmaceuticals: a retrospective analysis of whistleblower complaints. | PLoS medicine 20110401 |
| Rosuvastatin and primary cardiovascular prevention. Continue to use pravastatin or simvastatin. | Prescrire international 20110401 |
| Severe hypertriglyceridaemia during treatment with capecitabine. | British journal of cancer 20110329 |
| Amelioration of cisplatin-induced nephrotoxicity by pravastatin in mice. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110301 |
| Variation in the CBP gene involved in epigenetic control associates with cognitive function. | Neurobiology of aging 20110301 |
| Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice. | Pharmaceutical research 20110301 |
| Differential metabolic effects of distinct statins. | Atherosclerosis 20110301 |
| Influence of long-term treatment with pravastatin on the survival, evolution of cutaneous lesion and weight of animals infected by Leishmania amazonensis. | Experimental parasitology 20110301 |
| Mannose binding lectin 2 haplotypes do not affect the progression of coronary atherosclerosis in men with proven coronary artery disease treated with pravastatin. | Atherosclerosis 20110301 |
| Cerebral microbleeds are predictive of mortality in the elderly. | Stroke 20110301 |
| A novel use of oxidative coupling reactions for determination of some statins (cholesterol-lowering drugs) in pharmaceutical formulations. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110301 |
| Leptin and beyond: an odyssey to the central control of body weight. | The Yale journal of biology and medicine 20110301 |
| Depressogenic effects of medications: a review. | Dialogues in clinical neuroscience 20110301 |
| Comparison of Ezetimibe/Simvastatin 10/20 mg Versus Atorvastatin 20 mg in Achieving a Target Low Density Lipoprotein-Cholesterol Goal for Patients With Very High Risk. | Korean circulation journal 20110301 |
| [Effect of pravastatin on transportation of scutellarin in mouse liver and its mechanism]. | Yao xue xue bao = Acta pharmaceutica Sinica 20110301 |
| Low-density lipoprotein cholesterol goal attainment among Malaysian dyslipidemic patients. | The Southeast Asian journal of tropical medicine and public health 20110301 |
| More powerful search engine invalidates anonymity guidelines for case reports. | Healthcare informatics research 20110301 |
| Efficacy and safety of more intensive lowering of LDL cholesterol. | Lancet (London, England) 20110226 |
| C-reactive protein concentration and the vascular benefits of statin therapy: an analysis of 20,536 patients in the Heart Protection Study. | Lancet (London, England) 20110205 |
| Effect of niacin on preβ-1 high-density lipoprotein levels in diabetes. | Metabolism: clinical and experimental 20110201 |
| Potential mechanisms of hypocholesterolaemic effect of Thai spices/dietary extracts. | Natural product research 20110201 |
| Statin therapy in metabolic syndrome and hypertension post-JUPITER: what is the value of CRP? | Current atherosclerosis reports 20110201 |
| Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20110201 |
| What combination therapy with a statin, if any, would you recommend? | Current atherosclerosis reports 20110201 |
| The anti-ischemic and anti-anginal properties of statins. | Current atherosclerosis reports 20110201 |
| Antithrombotic properties of pravastatin reducing intra-thrombus fibrin deposition under high shear blood flow conditions. | Thrombosis and haemostasis 20110201 |
| Achievement of lipid targets with the combination of rosuvastatin and fenofibric Acid in patients with type 2 diabetes mellitus. | Cardiovascular drugs and therapy 20110201 |
| Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection. | Current atherosclerosis reports 20110201 |
| Comparative Effectiveness and Toxicity of Statins Among HIV-Infected Patients. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110201 |
| Role of tissue factor in pregnancy complications: crosstalk between coagulation and inflammation. | Thrombosis research 20110201 |
| [Genetic marker of statin-induced rhabdomyolysis]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110201 |
| Assessment of coronary atherosclerosis by IVUS and IVUS-based imaging modalities: progression and regression studies, tissue composition and beyond. | The international journal of cardiovascular imaging 20110201 |
| Long-term efficacy of adding fenofibric acid to moderate-dose statin therapy in patients with persistent elevated triglycerides. | Cardiovascular drugs and therapy 20110201 |
| [Pravastatin and rosiglitazone combination therapy upgrades the expression of ABCA1 in THP-1 macrophages]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110201 |
| [Retention behavior of statins in microemulsion liquid chromatography]. | Se pu = Chinese journal of chromatography 20110201 |
| Rosuvastatin reduces nonalcoholic fatty liver disease in patients with chronic hepatitis C treated with α-interferon and ribavirin: Rosuvastatin reduces NAFLD in HCV patients. | Hepatitis monthly 20110201 |
| World Kidney Day 2011 - Protect your kidneys, save your heart. | Archives of medical science : AMS 20110201 |
| The statins fluvastatin and pravastatin exert anti-flushing effects by improving vasomotor dysfunction through nitric oxide-mediated mechanisms in ovariectomized animals. | European journal of pharmacology 20110125 |
| Monitoring adherence to drug treatment by using change in cholesterol concentration: secondary analysis of trial data. | BMJ (Clinical research ed.) 20110121 |
| Construction of a novel expression vector in Pseudonocardia autotrophica and its application to efficient biotransformation of compactin to pravastatin, a specific HMG-CoA reductase inhibitor. | Biochemical and biophysical research communications 20110107 |
| Genetic variants in the KIF6 region and coronary event reduction from statin therapy. | Human genetics 20110101 |
| Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat. | Journal of molecular and cellular cardiology 20110101 |
| Differential effects of statins on endogenous H2S formation in perivascular adipose tissue. | Pharmacological research 20110101 |
| Use of ultra high performance liquid chromatography-tandem mass spectrometry to demonstrate decreased serum statin levels after extracorporeal LDL-cholesterol elimination. | Journal of biomedicine & biotechnology 20110101 |
| The fat-fed apolipoprotein E knockout mouse brachiocephalic artery in the study of atherosclerotic plaque rupture. | Journal of biomedicine & biotechnology 20110101 |
| Statin treatment decreased serum asymmetric dimethylarginine (ADMA) levels in ischemic stroke patients. | Journal of atherosclerosis and thrombosis 20110101 |
| Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death. | Journal of Alzheimer's disease : JAD 20110101 |
| Paradoxical decrease in HDL-cholesterol and apolipoprotein A1 with simvastatin and atorvastatin in a patient with type 2 diabetes. | Annals of clinical biochemistry 20110101 |
| Colchicine-induced rhabdomyolysis in a heart/lung transplant patient with concurrent use of cyclosporin, pravastatin, and azithromycin. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20110101 |
| Statins have an early antiplatelet effect in patients with acute myocardial infarction. | Platelets 20110101 |
| Standards of medical care in diabetes--2011. | Diabetes care 20110101 |
| Proximal tubule cell hypothesis for cardiorenal syndrome in diabetes. | International journal of nephrology 20110101 |
| Simvastatin is the statin that most efficiently protects against kainate-induced excitotoxicity and memory impairment. | Journal of Alzheimer's disease : JAD 20110101 |
| [Anti-atherosclerotic and anti-inflammatory effects of statin on cardiovascular disease and their mechanisms]. | Nihon rinsho. Japanese journal of clinical medicine 20110101 |
| Study design and rationale of 'Synergistic effect of combination therapy with cilostazol and ProbUcol on plaque stabilization and lesion REgression (SECURE)' study: a double-blind randomised controlled multicenter clinical trial. | Trials 20110101 |
| The proprotein convertase subtilisin/kexin type 9 gene E670G polymorphism and serum lipid levels in the Guangxi Bai Ku Yao and Han populations. | Lipids in health and disease 20110101 |
| Understanding diabetes in patients with HIV/AIDS. | Diabetology & metabolic syndrome 20110101 |
| Internet-based treatment for older adults with depression and co-morbid cardiovascular disease: protocol for a randomised, double-blind, placebo controlled trial. | BMC psychiatry 20110101 |
| ADPKD: Prototype of Cardiorenal Syndrome Type 4. | International journal of nephrology 20110101 |
| Transforming Growth Factor-β1 as a Common Target Molecule for Development of Cardiovascular Diseases, Renal Insufficiency and Metabolic Syndrome. | Cardiology research and practice 20110101 |
| NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol. | BMC pediatrics 20110101 |
| Novel adiponectin-resistin (AR) and insulin resistance (IRAR) indexes are useful integrated diagnostic biomarkers for insulin resistance, type 2 diabetes and metabolic syndrome: a case control study. | Cardiovascular diabetology 20110101 |
| The development and the use of experimental animal models to study the underlying mechanisms of CA formation. | Journal of biomedicine & biotechnology 20110101 |
| Lipoprotein-associated phospholipase A2 mass and activity in children with heterozygous familial hypercholesterolemia and unaffected siblings: effect of pravastatin. | Journal of clinical lipidology 20110101 |
| Pharmacological and non-pharmacological interventions to influence adipose tissue function. | Cardiovascular diabetology 20110101 |
| Pre-procedural atorvastatin mobilizes endothelial progenitor cells: clues to the salutary effects of statins on healing of stented human arteries. | PloS one 20110101 |
| Large-scale candidate gene analysis of HDL particle features. | PloS one 20110101 |
| Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats. | Respiratory research 20110101 |
| Relative survival: a useful tool to assess generalisability in longitudinal studies of health in older persons. | Emerging themes in epidemiology 20110101 |
| Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension. | PloS one 20110101 |
| Adiponectin provides cardiovascular protection in metabolic syndrome. | Cardiology research and practice 20110101 |
| Cardiovascular prevention of cognitive decline. | Cardiology research and practice 20110101 |
| Formation of Toxic Amyloid Fibrils by Amyloid β-Protein on Ganglioside Clusters. | International journal of Alzheimer's disease 20110101 |
| Restoration of cognitive deficits after statin feeding in TBI. | Restorative neurology and neuroscience 20110101 |
| Considering statins for cholesterol-reduction in children if lifestyle and diet changes do not improve their health: a review of the risks and benefits. | Vascular health and risk management 20110101 |
| ACE up the sleeve - are vascular patients medically optimized? | Vascular health and risk management 20110101 |
| Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). | BMC geriatrics 20110101 |
| Glucose-lowering effect of colestimide is associated with baseline HbA1c in type 2 diabetic patients with hypercholesterolemia. | Endocrine journal 20110101 |
| Statins do not prevent acute organ failure in ventilated ICU patients: single-centre retrospective cohort study. | Critical care (London, England) 20110101 |
| Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage. | Malaria journal 20110101 |
| Effect of atorvastatin and clopidogrel co-administration after coronary stenting in korean patients with stable angina. | Korean circulation journal 20110101 |
| An effective assessment of simvastatin-induced toxicity with NMR-based metabonomics approach. | PloS one 20110101 |
| Pravastatin versus simvastatin for prevention of contrast-induced nephropathy. | Journal of cardiovascular pharmacology and therapeutics 20110101 |
| Fixed-dose combination fenofibrate/pravastatin 160/40 mg versus simvastatin 20 mg monotherapy in adults with type 2 diabetes and mixed hyperlipidemia uncontrolled with simvastatin 20 mg: a double-blind, randomized comparative study. | Clinical therapeutics 20110101 |
| Animal models of cardiovascular diseases. | Journal of biomedicine & biotechnology 20110101 |
| Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis. | Critical care (London, England) 20110101 |
| Residual beta cell function in newly diagnosed type 1 diabetes after treatment with atorvastatin: the Randomized DIATOR Trial. | PloS one 20110101 |
| Acute-phase proteins: As diagnostic tool. | Journal of pharmacy & bioallied sciences 20110101 |
| Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease. | BMC medical genetics 20110101 |
| Statins as modulators of colon cancer cells induced cytokine secretion by human PBMC. | Vascular pharmacology 20110101 |
| Are all statins the same? Focus on the efficacy and tolerability of pitavastatin. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20110101 |
| Characterization of human erythrocytes as potential carrier for pravastatin: an in vitro study. | International journal of medical sciences 20110101 |
| Apolipoprotein E epsilon-4 polymorphism is associated with younger age at referral to a lipidology clinic and a poorer response to lipid-lowering therapy. | Lipids in health and disease 20110101 |
| Design of cohort studies in chronic diseases using routinely collected databases when a prescription is used as surrogate outcome. | BMC medical research methodology 20110101 |
| Statins: cardiovascular risk reduction in percutaneous coronary intervention-basic and clinical evidence of hyperacute use of statins. | International journal of hypertension 20110101 |
| Metabolic syndrome and renal injury. | Cardiology research and practice 20110101 |
| Structure modeling and inhibitor prediction ofNADP oxidoreductase enzyme from Methanobrevibacter smithii. | Bioinformation 20110101 |
| Effect of statin treatment on short term mortality after pneumonia episode: cohort study. | BMJ (Clinical research ed.) 20110101 |
| Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly. | Clinical interventions in aging 20110101 |
| Effects of short-term treatment with atorvastatin in smokers with asthma--a randomized controlled trial. | BMC pulmonary medicine 20110101 |
| ATP-binding cassette transporter A1 gene polymorphisms and serum lipid levels in young Greek nurses. | Lipids in health and disease 20110101 |
| A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. | Respiratory research 20110101 |
| Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males. | PloS one 20110101 |
| Doppler study of cerebral arteries in hypercholesterolemia. | Vascular health and risk management 20110101 |
| BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs. | BMC bioinformatics 20110101 |
| Pitavastatin increases ABCA1 expression by dual mechanisms: SREBP2-driven transcriptional activation and PPARα-dependent protein stabilization but without activating LXR in rat hepatoma McARH7777 cells. | Journal of pharmacological sciences 20110101 |
| Simvastatin suppresses dexamethasone-induced secretion of plasminogen activator inhibitor-1 in human bone marrow adipocytes. | BMC musculoskeletal disorders 20110101 |
| Serum lipoprotein levels in takotsubo cardiomyopathy vs. myocardial infarction. | International archives of medicine 20110101 |
| Acute modulation of vasoconstrictor responses by pravastatin in small vessels. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Pre-admission statin use and in-hospital severity of 2009 pandemic influenza A(H1N1) disease. | PloS one 20110101 |
| Urinary elimination of coproporphyrins is dependent on ABCC2 polymorphisms and represents a potential biomarker of MRP2 activity in humans. | Journal of biomedicine & biotechnology 20110101 |
| Roles of the WHHL rabbit in translational research on hypercholesterolemia and cardiovascular diseases. | Journal of biomedicine & biotechnology 20110101 |
| Globular adiponectin, acting via AdipoR1/APPL1, protects H9c2 cells from hypoxia/reoxygenation-induced apoptosis. | PloS one 20110101 |
| Rhabdomyolysis in an HIV-infected patient with impaired renal function concomitantly treated with rosuvastatin and lopinavir/ritonavir. | Antiviral therapy 20110101 |
| Pleiotropic effects of the HMG-CoA reductase inhibitors. | International journal of general medicine 20110101 |
| Clinical use and effectiveness of lipid lowering therapies in diabetes mellitus--an observational study from the Swedish National Diabetes Register. | PloS one 20110101 |
| Memory loss, behavioral changes, and slurred speech in a 49-year-old man. | Frontiers in neurology 20110101 |
| Genetic background of patients from a university medical center in Manhattan: implications for personalized medicine. | PloS one 20110101 |
| Increased serum myeloid-related protein 8/14 level is associated with atherosclerosis in type 2 diabetic patients. | Cardiovascular diabetology 20110101 |
| No connection between the level of exposition to statins in the population and the incidence/mortality of acute myocardial infarction: an ecological study based on Sweden's municipalities. | Journal of negative results in biomedicine 20110101 |
| Cardioprotective effects of pravastatin against lethal ventricular arrhythmias induced by reperfusion in the rat heart. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Place of pitavastatin in the statin armamentarium: promising evidence for a role in diabetes mellitus. | Drug design, development and therapy 20110101 |
| Concomitant use of simvastatin and amiodarone resulting in severe rhabdomyolysis: a case report and review of the literature. | Acta clinica Belgica 20110101 |
| A current evaluation of the safety of angiotensin receptor blockers and direct renin inhibitors. | Vascular health and risk management 20110101 |
| High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening. | PloS one 20110101 |
| Peripheral vascular dysfunction in chronic kidney disease. | Cardiology research and practice 20110101 |
| Dyslipidemia associated with chronic kidney disease. | The open cardiovascular medicine journal 20110101 |
| HIV and HAART-Associated Dyslipidemia. | The open cardiovascular medicine journal 20110101 |
| Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription. | International journal of biological sciences 20110101 |
| Orange juice and its component, hesperidin, decrease the expression of multidrug resistance-associated protein 2 in rat small intestine and liver. | Journal of biomedicine & biotechnology 20110101 |
| Dyslipidaemia in rheumatological autoimmune diseases. | The open cardiovascular medicine journal 20110101 |
| Dyslipidaemia of obesity, metabolic syndrome and type 2 diabetes mellitus: the case for residual risk reduction after statin treatment. | The open cardiovascular medicine journal 20110101 |
| Buffy coat specimens remain viable as a DNA source for highly multiplexed genome-wide genetic tests after long term storage. | Journal of translational medicine 20110101 |
| Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART). | Lipids in health and disease 20110101 |
| A post-trial survey to assess the impact of dissemination of results and unmasking on participants in a 13-year randomised controlled trial on age-related cataract. | Trials 20110101 |
| Comparison of preventive effect on cardiovascular events with different statins. -The CIRCLE study-. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Immunological and cardiometabolic risk factors in the prediction of type 2 diabetes and coronary events: MONICA/KORA Augsburg case-cohort study. | PloS one 20110101 |
| The effect of cardiovascular risk factors on the longitudinal evolution of the carotid intima medial thickness in children with type 1 diabetes mellitus. | Cardiovascular diabetology 20110101 |
| The chronic kidney disease model: a general purpose model of disease progression and treatment. | BMC medical informatics and decision making 20110101 |
| Internalization of Escherichia coli o157:h7 by bovine rectal epithelial cells. | Frontiers in microbiology 20110101 |
| Potential involvement of LOX-1 in functional consequences of endothelial senescence. | PloS one 20110101 |
| Renal function at the time of a myocardial infarction maintains prognostic value for more than 10 years. | BMC cardiovascular disorders 20110101 |
| Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors. | Pharmacology 20110101 |
| Pitavastatin suppresses diethylnitrosamine-induced liver preneoplasms in male C57BL/KsJ-db/db obese mice. | BMC cancer 20110101 |
| Relationship between hemoglobin A1c and cardiovascular disease in mild-to-moderate hypercholesterolemic Japanese individuals: subanalysis of a large-scale randomized controlled trial. | Cardiovascular diabetology 20110101 |
| Leptin in teleost fishes: an argument for comparative study. | Frontiers in physiology 20110101 |
| Antihypertriglyceridemia and anti-inflammatory activities of monascus-fermented dioscorea in streptozotocin-induced diabetic rats. | Experimental diabetes research 20110101 |
| Association of statin therapy with blood pressure control in hypertensive hypercholesterolemic outpatients in clinical practice. | Journal of cardiovascular disease research 20110101 |
| Generation of polyclonal antibody with high avidity to rosuvastatin and its use in development of highly sensitive ELISA for determination of rosuvastatin in plasma. | Chemistry Central journal 20110101 |
| Insulin-regulated Srebp-1c and Pck1 mRNA expression in primary hepatocytes from zucker fatty but not lean rats is affected by feeding conditions. | PloS one 20110101 |
| Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation. | Vascular health and risk management 20110101 |
| Circulating adiponectin levels are lower in Latino versus non-Latino white patients at risk for cardiovascular disease, independent of adiposity measures. | BMC endocrine disorders 20110101 |
| The impact of hypertension on patients with acute coronary syndromes. | International journal of hypertension 20110101 |
| Association between use of HMG CoA reductase inhibitors and mortality in HIV-infected patients. | PloS one 20110101 |
| Dyslipidemia induced by drugs used for the prevention and treatment of vascular diseases. | The open cardiovascular medicine journal 20110101 |
| Influence of atorvastatin on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients: a prospective, randomized, double-masked, placebo-controlled study. | Arthritis research & therapy 20110101 |
| Treating statin-intolerant patients. | Diabetes, metabolic syndrome and obesity : targets and therapy 20110101 |
| Clinical therapeutics in pregnancy. | Journal of biomedicine & biotechnology 20110101 |
| Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality. | Stroke research and treatment 20110101 |
| Adherence with statins in a real-life setting is better when associated cardiovascular risk factors increase: a cohort study. | BMC cardiovascular disorders 20110101 |
| Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey. | Drug design, development and therapy 20110101 |
| Optimal therapeutic strategy for treating patients with hypertension and atherosclerosis: focus on olmesartan medoxomil. | Vascular health and risk management 20110101 |
| Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20110101 |
| Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains. | Lipids in health and disease 20110101 |
| Mesenchymal stem cell transplantation ameliorates motor function deterioration of spinocerebellar ataxia by rescuing cerebellar Purkinje cells. | Journal of biomedical science 20110101 |
| Transport characteristics of tryptanthrin and its inhibitory effect on P-gp and MRP2 in Caco-2 cells. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20110101 |
| Anti-inflammatory effect of fluvastatin on IL-8 production induced by Pseudomonas aeruginosa and Aspergillus fumigatus antigens in cystic fibrosis. | PloS one 20110101 |
| Comparative effect of olmesartan and candesartan on lipid metabolism and renal function in patients with hypertension: a retrospective observational study. | Cardiovascular diabetology 20110101 |
| Antihyperlipidemic effects of Pleurotus ostreatus (oyster mushrooms) in HIV-infected individuals taking antiretroviral therapy. | BMC complementary and alternative medicine 20110101 |
| Inflammatory concepts of obesity. | International journal of inflammation 20110101 |
| A systems biology strategy for predicting similarities and differences of drug effects: evidence for drug-specific modulation of inflammation in atherosclerosis. | BMC systems biology 20110101 |
| Tacrolimus and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors: An interaction study in CYP3A5 non-expressors, renal transplant recipients. | Indian journal of pharmacology 20110101 |
| Comparison of nebivolol and atenolol on blood pressure, blood sugar, and lipid profile in patients of essential hypertension. | Indian journal of pharmacology 20110101 |
| ATP-Sensitive Potassium Channel Currents in Eccentrically Hypertrophied Cardiac Myocytes of Volume-Overloaded Rats. | International journal of cell biology 20110101 |
| Response by sex to statin plus ezetimibe or statin monotherapy: a pooled analysis of 22,231 hyperlipidemic patients. | Lipids in health and disease 20110101 |
| Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts. | Respiratory research 20110101 |
| Treatment of allergic asthma: modulation of Th2 cells and their responses. | Respiratory research 20110101 |
| Age-related white matter changes. | Journal of aging research 20110101 |
| Myeloid-related protein activity in rheumatoid arthritis. | International journal of inflammation 20110101 |
| Trends in the Use of Evidence-based Therapies Early in the Course of Acute Myocardial Infarction and its Influence on Short Term Patient Outcomes. | The open cardiovascular medicine journal 20110101 |
| Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study. | Lipids in health and disease 20110101 |
| Inhibition of lipoprotein-associated phospholipase A2 ameliorates inflammation and decreases atherosclerotic plaque formation in ApoE-deficient mice. | PloS one 20110101 |
| Studies on the antibacterial effects of statins--in vitro and in vivo. | PloS one 20110101 |
| Lipid-lowering therapy: who can benefit? | Vascular health and risk management 20110101 |
| Clinical characteristics and outcomes of patients with acute coronary syndrome and prior coronary artery bypass grafting in a large middle eastern cohort. | The open cardiovascular medicine journal 20110101 |
| C-reactive protein and genetic variants and cognitive decline in old age: the PROSPER study. | PloS one 20110101 |
| No evidence for statin-induced proteinuria in healthy volunteers as assessed by proteomic analysis. | Journal of biomedicine & biotechnology 20110101 |
| APPROACH-J study: design, rationale, and baseline data of the affirmation primary prevention with pravastatin in reduction of occlusive atherosclerotic complications in hypercholesterolemia--Japan study. | Journal of atherosclerosis and thrombosis 20110101 |
| Statins enhance clonal growth of late outgrowth endothelial progenitors and increase myocardial capillary density in the chronically ischemic heart. | PloS one 20110101 |
| Observational study of lipid profile and LDL particle size in patients with metabolic syndrome. | Lipids in health and disease 20110101 |
| Tissue factor, blood coagulation, and beyond: an overview. | International journal of inflammation 20110101 |
| Exposure to statins and risk of common cancers: a series of nested case-control studies. | BMC cancer 20110101 |
| Administration of simvastatin after kainic acid-induced status epilepticus restrains chronic temporal lobe epilepsy. | PloS one 20110101 |
| Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A₂ (Lp-PLA₂): a review. | Lipids in health and disease 20110101 |
| A retrospective cohort study of the potency of lipid-lowering therapy and race-gender differences in LDL cholesterol control. | BMC cardiovascular disorders 20110101 |
| The effect of the addition of resistance training to a dietary education intervention on apolipoproteins and diet quality in overweight and obese older adults. | Clinical interventions in aging 20110101 |
| Imaging of zebrafish in vivo with second-harmonic generation reveals shortened sarcomeres associated with myopathy induced by statin. | PloS one 20110101 |
| Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses. | BMC medical genetics 20110101 |
| Age, gender, insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients. | Cardiovascular diabetology 20110101 |
| Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction. | PloS one 20110101 |
| Emerging therapeutic strategies to enhance HDL function. | Lipids in health and disease 20110101 |
| Effectiveness of Ezetimibe in Reducing the Estimated Risk for Fatal Cardiovascular Events in Hypercholesterolaemic Patients with Inadequate Lipid Control While on Statin Monotherapy as Measured by the SCORE Model. | Advances in preventive medicine 20110101 |
| Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models. | Lipids in health and disease 20110101 |
| SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group. | BMC medical genetics 20110101 |
| Pleiotropic effects of statins in distal human pulmonary artery smooth muscle cells. | Respiratory research 20110101 |
| Challenges associated with tyrosine kinase inhibitor therapy for metastatic thyroid cancer. | Journal of thyroid research 20110101 |
| Pharmacogenetics of OATP transporters reveals that SLCO1B1 c.388A>G variant is determinant of increased atorvastatin response. | International journal of molecular sciences 20110101 |
| Enteric microbiome metabolites correlate with response to simvastatin treatment. | PloS one 20110101 |
| Effects of atorvastatin and rosuvastatin on high-sensitivity C-reactive protein and lipid profile in obese type 2 diabetes mellitus patients. | Journal of pharmacology & pharmacotherapeutics 20110101 |
| South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome. | Indian journal of endocrinology and metabolism 20110101 |
| Estimated glomerular filtration rate and the risk of major vascular events and all-cause mortality: a meta-analysis. | PloS one 20110101 |
| Takotsubo cardiomyopathy after a dancing session: a case report. | Journal of medical case reports 20110101 |
| Prognostic effect size of cardiovascular biomarkers in datasets from observational studies versus randomised trials: meta-epidemiology study. | BMJ (Clinical research ed.) 20110101 |
| Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. | PloS one 20110101 |
| Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin. | Lipids in health and disease 20110101 |
| Recognition of morphometric vertebral fractures by artificial neural networks: analysis from GISMO Lombardia Database. | PloS one 20110101 |
| Simvastatin protects auditory hair cells from gentamicin-induced toxicity and activates Akt signaling in vitro. | BMC neuroscience 20110101 |
| Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter. | Clinical Medicine Insights. Cardiology 20110101 |
| Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis. | Journal of inflammation research 20110101 |
| Vascular involvement in systemic sclerosis (scleroderma). | Journal of inflammation research 20110101 |
| Role of raltegravir in the management of HIV-1 infection. | HIV/AIDS (Auckland, N.Z.) 20110101 |
| Decreased glomerular filtration rate is associated with mortality and cardiovascular events in patients with hypertension: a prospective study. | PloS one 20110101 |
| Distinct effects of acute pretreatment with lipophilic and hydrophilic statins on myocardial stunning, arrhythmias and lethal injury in the rat heart subjected to ischemia/reperfusion. | Physiological research 20110101 |
| Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats. | Cardiovascular diabetology 20110101 |
| Adaptation to statins restricts human tumour growth in Nude mice. | BMC cancer 20110101 |
| Acute myocardial infarction in young adults with antiphospholipid syndrome: report of two cases and literature review. | The Pan African medical journal 20110101 |
| Statins and prevention of infections: systematic review and meta-analysis of data from large randomised placebo controlled trials. | BMJ (Clinical research ed.) 20110101 |
| Enhancement of lutein production in Chlorella sorokiniana (Chorophyta) by improvement of culture conditions and random mutagenesis. | Marine drugs 20110101 |
| Gene-drug interaction in stroke. | Stroke research and treatment 20110101 |
| Current state of cardiac rehabilitation in Germany: patient characteristics, risk factor management and control status, by education level. | Vascular health and risk management 20110101 |
| Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion. | PloS one 20110101 |
| Molecular diagnosis of analbuminemia: a new case caused by a nonsense mutation in the albumin gene. | International journal of molecular sciences 20110101 |
| Medical angioplasty - hope and expectations: an optimistic overview. | Journal of family & community medicine 20110101 |
| Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by δ-tocotrienol and quercetin. | Lipids in health and disease 20110101 |
| [Therapeutic use Hibiscus sabadariffa extract in the treatment of hypercholesterolemia. A randomized clinical trial]. | Revista medica del Instituto Mexicano del Seguro Social 20110101 |
| Long-term efficacy of upstream therapy with lipophilic or hydrophilic statins on antiarrhythmic drugs in patients with paroxysmal atrial fibrillation: comparison between atorvastatin and pravastatin. | International heart journal 20110101 |
| Assessment of monacolin in the fermented products using Monascus purpureus FTC5391. | Journal of biomedicine & biotechnology 20110101 |
| Protective Effects of Simvastatin, a Lipid Lowering Agent, against Oxidative Damage in Experimental Diabetic Rats. | Journal of lipids 20110101 |
| Cholesterol, C-Reactive Protein, and Periodontitis: HMG-CoA-Reductase Inhibitors (Statins) as Effect Modifiers. | ISRN dentistry 20110101 |
| Systematic drug repositioning based on clinical side-effects. | PloS one 20110101 |
| Statin-associated muscular and renal adverse events: data mining of the public version of the FDA adverse event reporting system. | PloS one 20110101 |
| The dynamin chemical inhibitor dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages. | PloS one 20110101 |
| Preventing Cardio-renal Syndrome Rather than Treating It: Could Statins Play A Role? | The open cardiovascular medicine journal 20110101 |
| Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites. | PloS one 20110101 |
| A common KIF6 polymorphism increases vulnerability to low-density lipoprotein cholesterol: two meta-analyses and a meta-regression analysis. | PloS one 20110101 |
| Lipodystrophy in HIV patients: its challenges and management approaches. | HIV/AIDS (Auckland, N.Z.) 20110101 |
| Efficacy and safety of gonadotropin-releasing hormone agonists used in the treatment of prostate cancer. | Drug, healthcare and patient safety 20110101 |
| Mthfs is an Essential Gene in Mice and a Component of the Purinosome. | Frontiers in genetics 20110101 |
| Protein modification by dicarbonyl molecular species in neurodegenerative diseases. | Journal of amino acids 20110101 |
| Optimal management of peripheral arterial disease for the non-specialist. | The Ulster medical journal 20110101 |
| Experience in the management of the severe form of human influenza A H1N1 pneumonia in an intensive care unit. | Cirugia y cirujanos 20110101 |
| No consensus on definition criteria for stroke registry common data elements. | Cerebrovascular diseases extra 20110101 |
| Statin Hepatotoxicity: Is it a Real Concern? | Heart views : the official journal of the Gulf Heart Association 20110101 |
| Statins: past and present. | Heart views : the official journal of the Gulf Heart Association 20110101 |
| In vivo bioavailability studies of sumatriptan succinate buccal tablets. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101 |
| High-efficiency loading and controlled release of highly water-soluble drug, pravastatin sodium by use of cross-linked β-cyclodextrin. | International journal of pharmaceutical investigation 20110101 |
| Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223 |
| Liposomal pravastatin inhibits tumor growth by targeting cancer-related inflammation. | Journal of controlled release : official journal of the Controlled Release Society 20101220 |
| A mouse macrophage lipidome. | The Journal of biological chemistry 20101217 |
| Preventive effects of pravastatin on thrombin-triggered vascular responses via Akt/eNOS and RhoA/Rac1 pathways in vivo. | Cardiovascular research 20101201 |
| Lifibrol as a model compound for a novel lipid-lowering mechanism of action. | Journal of cardiovascular pharmacology and therapeutics 20101201 |
| Lipophilic statins prevent matrix metalloproteinase-mediated cartilage collagen breakdown by inhibiting protein geranylgeranylation. | Annals of the rheumatic diseases 20101201 |
| Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits. | Molecular and cellular neurosciences 20101201 |
| The addition of pravastatin to chemotherapy in advanced gastric carcinoma: a randomised phase II trial. | European journal of cancer (Oxford, England : 1990) 20101201 |
| In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| Successful treatment of lipoprotein glomerulopathy in a daughter and a mother using niceritrol. | Clinical and experimental nephrology 20101201 |
| Premature senescence of vascular cells is induced by HIV protease inhibitors: implication of prelamin A and reversion by statin. | Arteriosclerosis, thrombosis, and vascular biology 20101201 |
| IL-2 costimulation enables statin-mediated activation of human NK cells, preferentially through a mechanism involving CD56+ dendritic cells. | Cancer research 20101201 |
| Application of physiologically based pharmacokinetic modeling and clearance concept to drugs showing transporter-mediated distribution and clearance in humans. | Journal of pharmacokinetics and pharmacodynamics 20101201 |
| Atorvastatin-induced acute elevation of hepatic enzymes and the absence of cross-toxicity of pravastatin. | International journal of clinical pharmacology and therapeutics 20101201 |
| Clearance (née Rowland) concepts: a downdate and an update. | Journal of pharmacokinetics and pharmacodynamics 20101201 |
| Cardiovascular diseases. Introduction. | Atherosclerosis. Supplements 20101201 |
| Pitavastatin - results from phase III & IV. | Atherosclerosis. Supplements 20101201 |
| Pitavastatin - from clinical trials to clinical practice. | Atherosclerosis. Supplements 20101201 |
| A retrospective study on the efficacy of a ten-milligram dosage of atorvastatin for treatment of hypercholesterolemia in type 2 diabetes mellitus patients. | Korean diabetes journal 20101201 |
| Effect of atorvastatin in patients with chronic heart failure - insights from randomized clinical trials. | Archives of medical science : AMS 20101201 |
| KIF6 p.Trp719Arg Testing to Assess Risk of Coronary Artery Disease and/or Statin Response. | PLoS currents 20101126 |
| What is the optimal blood pressure in patients after acute coronary syndromes?: Relationship of blood pressure and cardiovascular events in the PRavastatin OR atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction (PROVE IT-TIMI) 22 trial. | Circulation 20101123 |
| Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. | Lancet (London, England) 20101113 |
| Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial. | Lancet (London, England) 20101113 |
| Simvastatin and purine analogs have a synergic effect on apoptosis of chronic lymphocytic leukemia cells. | Annals of hematology 20101101 |
| Prevalence and overlap of different lipid abnormalities in statin-treated patients at high cardiovascular risk in clinical practice in Germany. | Clinical research in cardiology : official journal of the German Cardiac Society 20101101 |
| Simvastatin induces osteogenic differentiation of murine embryonic stem cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20101101 |
| Modulation of the Rho/ROCK pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity. | Current drug targets 20101101 |
| Effect of pravastatin on bleomycin-induced acute lung injury and pulmonary fibrosis. | Clinical and experimental pharmacology & physiology 20101101 |
| The nitric oxide-donating pravastatin, NCX 6550, inhibits cytokine release and NF-κB activation while enhancing PPARγ expression in human monocyte/macrophages. | Pharmacological research 20101101 |
| Molecular cloning and characterization of the global regulator LaeA in Penicillium citrinum. | Biotechnology letters 20101101 |
| Induction of endothelial nitric oxide synthase, SIRT1, and catalase by statins inhibits endothelial senescence through the Akt pathway. | Arteriosclerosis, thrombosis, and vascular biology 20101101 |
| Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples. | Archives of toxicology 20101101 |
| Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A. | PLoS genetics 20101101 |
| Diabetes & coronary heart disease: current perspectives. | The Indian journal of medical research 20101101 |
| Pravastatin potentiates increases in serum adiponectin concentration in dyslipidemic patients receiving thiazolidinedione: the DOLPHIN study. | Journal of atherosclerosis and thrombosis 20101027 |
| Effects of pravastatin on murine chronic graft-versus-host disease. | Transplantation 20101027 |
| Liquid chromatography-tandem mass spectrometric assay for pravastatin and two isomeric metabolites in mouse plasma and tissue homogenates. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015 |
| LC-MS/MS method for the determination of several drugs used in combined cardiovascular therapy in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015 |
| Investigation of microcystin congener-dependent uptake into primary murine neurons. | Environmental health perspectives 20101001 |
| Coadministration of dalcetrapib with pravastatin, rosuvastatin, or simvastatin: no clinically relevant drug-drug interactions. | Journal of clinical pharmacology 20101001 |
| Atherogenic dyslipidemia: cardiovascular risk and dietary intervention. | Lipids 20101001 |
| Enhancement of recombinant enzyme activity in cpxA-deficient mutant of Escherichia coli. | Journal of bioscience and bioengineering 20101001 |
| Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics. | Diabetes & vascular disease research 20101001 |
| Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide. | Pharmaceutical research 20101001 |
| Use of statins in patients with chronic hepatitis C. | Southern medical journal 20101001 |
| KIF6 polymorphism as a predictor of risk of coronary events and of clinical event reduction by statin therapy. | The American journal of cardiology 20101001 |
| Acceptable incremental cost effectiveness ratio for use of new drugs, cases in statin therapies. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101001 |
| Atorvastatin-induced pancreatitis. | Indian journal of pharmacology 20101001 |
| [Indications for statin therapy in patients with acute coronary syndrome of ischemic origin]. | Giornale italiano di cardiologia (2006) 20101001 |
| Dyslipidaemia in hypertensive obese type 2 diabetic patients in Jamaica. | Archives of medical science : AMS 20101001 |
| Efficacy and safety of adding fenofibrate 160 mg in high-risk patients with mixed hyperlipidemia not controlled by pravastatin 40 mg monotherapy. | The American journal of cardiology 20100915 |
| Progression of brain atrophy and cognitive decline in diabetes mellitus: a 3-year follow-up. | Neurology 20100914 |
| Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner. | Neurobiology of aging 20100901 |
| Lipid Lowering Activity of Anthocephalus indicus Root in Hyperlipidemic Rats. | Evidence-based complementary and alternative medicine : eCAM 20100901 |
| No significant effect of uridine or pravastatin treatment for HIV lipoatrophy in men who have ceased thymidine analogue nucleoside reverse transcriptase inhibitor therapy: a randomized trial. | HIV medicine 20100901 |
| Drug-drug interactions between raltegravir and pravastatin in healthy volunteers. | Journal of acquired immune deficiency syndromes (1999) 20100901 |
| Do statins beneficially or adversely affect glucose homeostasis? | Current vascular pharmacology 20100901 |
| Lung function and risk of type 2 diabetes and fatal and nonfatal major coronary heart disease events: possible associations with inflammation. | Diabetes care 20100901 |
| Reduction of endoplasmic reticulum stress--a novel mechanism of action of statins in the protection against atherosclerosis. | Atherosclerosis 20100901 |
| Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20100901 |
| Biosynthesis of lovastatin and related metabolites formed by fungal iterative PKS enzymes. | Biopolymers 20100901 |
| On the combined effect of statins and lycopene on cytokine production by human peripheral blood cells. | Heart and vessels 20100901 |
| Effectiveness, safety and cost of drug substitution in hypertension. | British journal of clinical pharmacology 20100901 |
| Results of a safety initiative for patients on concomitant amiodarone and simvastatin therapy in a Veterans Affairs medical center. | Journal of managed care pharmacy : JMCP 20100901 |
| Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. | British journal of pharmacology 20100901 |
| Office-based global cardiometabolic risk assessment: a simple tool incorporating nontraditional markers. | Critical pathways in cardiology 20100901 |
| Disparate effects of atorvastatin compared with simvastatin on C-reactive protein concentrations in patients with type 2 diabetes. | Diabetes care 20100901 |
| Persistence with statins and onset of rheumatoid arthritis: a population-based cohort study. | PLoS medicine 20100901 |
| Literature mining for the discovery of hidden connections between drugs, genes and diseases. | PLoS computational biology 20100901 |
| Drug off-target effects predicted using structural analysis in the context of a metabolic network model. | PLoS computational biology 20100901 |
| Ultrasound diagnosis of bilateral quadriceps tendon rupture after statin use. | The western journal of emergency medicine 20100901 |
| [OATP 1B1 T521C/A388G is an important polymorphism gene related to neonatal hyperbilirubinemia]. | Zhonghua er ke za zhi = Chinese journal of pediatrics 20100901 |
| Association between lowering low-density lipoprotein cholesterol with pravastatin and primary prevention of cardiovascular disease in mild to moderate hypercholesterolemic Japanese. | Journal of atherosclerosis and thrombosis 20100831 |
| Pravastatin attenuates cardiac dysfunction induced by lysophosphatidylcholine in isolated rat hearts. | European journal of pharmacology 20100825 |
| On-statin cholesteryl ester transfer protein mass and risk of recurrent coronary events (from the pravastatin or atorvastatin evaluation and infection therapy-thrombolysis in myocardial infarction 22 [PROVE IT-TIMI 22] study). | The American journal of cardiology 20100815 |
| Can a statin neutralize the cardiovascular risk of unhealthy dietary choices? | The American journal of cardiology 20100815 |
| Pharmacokinetic modeling of the hepatobiliary transport mediated by cooperation of uptake and efflux transporters. | Drug metabolism reviews 20100801 |
| KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study. | European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20100801 |
| Telomeres are shorter in myocardial infarction patients compared to healthy subjects: correlation with environmental risk factors. | Journal of molecular medicine (Berlin, Germany) 20100801 |
| Effect of combining ACE inhibitor and statin in lupus-prone mice. | Clinical immunology (Orlando, Fla.) 20100801 |
| Scavenger receptor-B1 and luteal function in mice. | Journal of lipid research 20100801 |
| Effect of pravastatin on ventricular arrhythmias in infarcted rats: role of connexin43. | Journal of applied physiology (Bethesda, Md. : 1985) 20100801 |
| Unusual pattern of dyslipidemia in children receiving steroid minimization immunosuppression after renal transplantation. | Clinical journal of the American Society of Nephrology : CJASN 20100801 |
| Anatomy and physiology of coronary blood flow. | Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20100801 |
| Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes. | Diabetes 20100801 |
| Comparative study of bezafibrate and pravastatin in patients with coronary artery disease and high levels of remnant lipoprotein. | Circulation journal : official journal of the Japanese Circulation Society 20100801 |
| Erythema multiforme photoinduced by statins. | Photodermatology, photoimmunology & photomedicine 20100801 |
| Effects of fungal statins on high-glucose-induced mouse mesangial cell hypocontractility may involve filamentous actin, t-complex polypeptide 1 subunit beta, and glucose regulated protein 78. | Translational research : the journal of laboratory and clinical medicine 20100801 |
| Activation of c-Jun N-terminal kinase is required for mevastatin-induced apoptosis of salivary adenoid cystic carcinoma cells. | Anti-cancer drugs 20100801 |
| Comparison of atorvastatin 80 mg/day versus simvastatin 20 to 40 mg/day on frequency of cardiovascular events late (five years) after acute myocardial infarction (from the Incremental Decrease in End Points through Aggressive Lipid Lowering [IDEAL] trial). | The American journal of cardiology 20100801 |
| Acute activation of eNOS by statins involves scavenger receptor-B1, G protein subunit Gi, phospholipase C and calcium influx. | British journal of pharmacology 20100801 |
| Pravastatin administration does not induce detrimental effects on hemodynamics and collaterals of portal hypertensive rats. | Journal of gastroenterology and hepatology 20100801 |
| Pitavastatin for the treatment of primary hyperlipidemia and mixed dyslipidemia. | Expert review of cardiovascular therapy 20100801 |
| The cardio-protective properties of Ncx-6550, a nitric oxide donating pravastatin, in the mouse. | Microcirculation (New York, N.Y. : 1994) 20100801 |
| Identification of attractive drug targets in neglected-disease pathogens using an in silico approach. | PLoS neglected tropical diseases 20100801 |
| Complex atheromatosis of the aortic arch in cerebral infarction. | Current cardiology reviews 20100801 |
| Flavonoids: antioxidants against atherosclerosis. | Nutrients 20100801 |
| Switching to aggressive statin improves vascular endothelial function in patients with stable coronary artery disease. | Journal of atherosclerosis and thrombosis 20100730 |
| Chronic cholesterol depletion using statin impairs the function and dynamics of human serotonin(1A) receptors. | Biochemistry 20100706 |
| Effect of HMG-CoA reductase inhibitors on vascular cell apoptosis: beneficial or detrimental? | Atherosclerosis 20100701 |
| Association between percutaneous coronary intervention and long-term C-reactive protein levels in patients with acute coronary syndromes. | Journal of thrombosis and thrombolysis 20100701 |
| Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1. | Molecular pharmacology 20100701 |
| A prospective analysis of elevated fasting glucose levels and cognitive function in older people: results from PROSPER and the Rotterdam Study. | Diabetes 20100701 |
| The influence of Sam-Chil-Geun (Panax notoginseng) on the serum lipid levels and inflammations of rats with hyperlipidemia induced by poloxamer-407. | Yonsei medical journal 20100701 |
| Lipid-lowering drugs and heart failure: where do we go after the statin trials? | Current opinion in cardiology 20100701 |
| Using pravastatin to improve the vascular reactivity in a mouse model of soluble fms-like tyrosine kinase-1-induced preeclampsia. | Obstetrics and gynecology 20100701 |
| Lack of effect of statins on maintenance of normal sinus rhythm following electrical cardioversion of persistent atrial fibrillation. | International journal of clinical practice 20100701 |
| Effects of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor pravastatin on membrane lipids and membrane associated functions of Methanothermobacter thermautotrophicus. | Folia microbiologica 20100701 |
| Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient. | PLoS pathogens 20100701 |
| Treatment with pravastatin and fenofibrate improves atherogenic lipid profiles but not inflammatory markers in ACTG 5087. | Journal of clinical lipidology 20100701 |
| Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets. | The Journal of biological chemistry 20100618 |
| A novel statin-mediated 'prenylation block-and-release' assay provides insight into the membrane targeting mechanisms of small GTPases. | Biochemical and biophysical research communications 20100618 |
| Effect of pravastatin on experimental diabetic wound healing. | The Journal of surgical research 20100615 |
| Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani. | Chembiochem : a European journal of chemical biology 20100614 |
| Residential traffic exposure, pulse pressure, and C-reactive protein: consistency and contrast among exposure characterization methods. | Environmental health perspectives 20100601 |
| Mitochondrial K(ATP) channels-derived reactive oxygen species activate pro-survival pathway in pravastatin-induced cardioprotection. | Apoptosis : an international journal on programmed cell death 20100601 |
| Activation of AMP-activated protein kinase inhibits oxidized LDL-triggered endoplasmic reticulum stress in vivo. | Diabetes 20100601 |
| Enatiomerically pure hydroxycarboxylic acids: current approaches and future perspectives. | Applied microbiology and biotechnology 20100601 |
| Development of a high-throughput method for the determination of ethosuximide in human plasma by liquid chromatography mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601 |
| Retrospective, observation study: Quantitative and qualitative effect of ezetimibe and HMG-CoA reductase inhibitors on LDL-cholesterol: are there disappearance thresholds for small, dense LDL and IDL? | Recent patents on cardiovascular drug discovery 20100601 |
| Post-prandial lipid metabolism, lipid-modulating agents and cerebrovascular integrity: implications for dementia risk. | Atherosclerosis. Supplements 20100601 |
| Severe hypocholesterolaemia is often neglected in haematological malignancies. | European journal of cancer (Oxford, England : 1990) 20100601 |
| In vitro synergistic interactions of the effects of various statins and azoles against some clinically important fungi. | FEMS microbiology letters 20100601 |
| Aspirin and pravastatin reduce lectin-like oxidized low density lipoprotein receptor-1 expression, adhesion molecules and oxidative stress in human coronary artery endothelial cells. | Chinese medical journal 20100601 |
| Molecular mechanism of ochratoxin a transport in the kidney. | Toxins 20100601 |
| A historical perspective on the discovery of statins. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100511 |
| Lipophilic but not hydrophilic statins selectively induce cell death in gynaecological cancers expressing high levels of HMGCoA reductase. | Journal of cellular and molecular medicine 20100501 |
| Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly. | Journal of lipid research 20100501 |
| Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). | Atherosclerosis 20100501 |
| Relationships between metabolic syndrome and other baseline factors and the efficacy of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes and hypercholesterolemia. | Diabetes care 20100501 |
| Inhibition of necrotic actions of nitrogen-containing bisphosphonates (NBPs) and their elimination from bone by etidronate (a non-NBP): a proposal for possible utilization of etidronate as a substitution drug for NBPs. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20100501 |
| Lipoprotein-associated phospholipase A2 activity and incident coronary heart disease among men and women with type 2 diabetes. | Diabetes 20100501 |
| Different effects of commonly prescribed statins on abdominal aortic aneurysm wall biology. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20100501 |
| Coronary plaque regression and lifestyle modification in patients treated with pravastatin. - Assessment mainly by daily aerobic exercise and an increase in the serum level of high-density lipoprotein cholesterol -. | Circulation journal : official journal of the Japanese Circulation Society 20100501 |
| Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Arg allele from the cholesterol and recurrent events trial. | The American journal of cardiology 20100501 |
| Correlates of the severity of coronary atherosclerosis in long-term kidney transplant patients. | Journal of Korean medical science 20100501 |
| Involvement of an influx transporter in the blood-brain barrier transport of naloxone. | Biopharmaceutics & drug disposition 20100501 |
| Approach to the patient who is intolerant of statin therapy. | The Journal of clinical endocrinology and metabolism 20100501 |
| [Pravastatin inhibits the expression of syndecan-4 protein in tumor necrosis factor-alpha-induced rat vascular smooth muscle cells in vitro]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100501 |
| [Mevastatin inhibits the differentiation of thyroid-associated ophthalmopathy derived orbital preadipocytes]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100501 |
| [Effects of pravastatin on the expression of transforming growth factor-beta 1 in cardiac fibroblasts]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100501 |
| The Role of Asymmetric Dimethylarginine (ADMA) in Endothelial Dysfunction and Cardiovascular Disease. | Current cardiology reviews 20100501 |
| Lipid metabolism and HCV infection. | Viruses 20100501 |
| Long-term efficacy of pravastatin therapy in diabetic patients undergoing complete coronary revascularization. | Journal of atherosclerosis and thrombosis 20100430 |
| Can intensive lipid-lowering therapy with statins ameliorate atherosclerosis in Japanese patients? Rationale and design of the JART study. | Journal of atherosclerosis and thrombosis 20100430 |
| Differential effects of statins (pravastatin or simvastatin) on ventricular ectopic complexes: Galpha(i2), a possible molecular marker for ventricular irritability. | The American journal of cardiology 20100415 |
| Rapid multilabel detection of geranylgeranylated proteins by using bioorthogonal ligation chemistry. | Chembiochem : a European journal of chemical biology 20100412 |
| Statins improve visual field alterations related to hypercholesterolemia. | Atherosclerosis 20100401 |
| Effects of mevastatin on grafted bone in MRL/MpJ mice. | Connective tissue research 20100401 |
| Tolerability of pravastatin in pediatric hematopoietic stem cell transplant patients with bronchiolitis obliterans. | Journal of pediatric hematology/oncology 20100401 |
| Assessment of a safety enhancement to the hospital medication reconciliation process for elderly patients. | The American journal of geriatric pharmacotherapy 20100401 |
| A systematic review and meta-analysis on the therapeutic equivalence of statins. | Journal of clinical pharmacy and therapeutics 20100401 |
| [Effects of pravastatin on the proliferation and invasion of human hepatocarcinoma HepG2 cell line]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100401 |
| Ochratoxin a: general overview and actual molecular status. | Toxins 20100401 |
| Effect of olmesartan and pravastatin on experimental cerebral aneurysms in rats. | Brain research 20100331 |
| In vitro antioxidant activity of pravastatin provides vascular protection. | European journal of pharmacology 20100325 |
| Statins in acute coronary syndromes and genetic insight. | Journal of the American College of Cardiology 20100323 |
| Letter by Superko and King regarding article, 'Lipid Treatment Assessment Project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals'. | Circulation 20100309 |
| Angiotensin II receptor blocker and statins lower elevated levels of osteopontin in essential hypertension--results from the EUTOPIA trial. | Atherosclerosis 20100301 |
| Impact of inactivity and exercise on the vasculature in humans. | European journal of applied physiology 20100301 |
| Association of the TNF-{alpha}-C-857T polymorphism with resistance to the cholesterol-lowering effect of HMG-CoA reductase inhibitors in type 2 diabetic subjects. | Diabetes care 20100301 |
| Activation of hemostasis and decline in cognitive function in older people. | Arteriosclerosis, thrombosis, and vascular biology 20100301 |
| Expression, localization, and pharmacological role of Kv7 potassium channels in skeletal muscle proliferation, differentiation, and survival after myotoxic insults. | The Journal of pharmacology and experimental therapeutics 20100301 |
| BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1. | Arteriosclerosis, thrombosis, and vascular biology 20100301 |
| Effect of statins on the viability of macrophages and smooth muscle cells. | Journal of cardiovascular pharmacology 20100301 |
| Statins for the treatment of obstetric complications in antiphospholipid syndrome? | Journal of reproductive immunology 20100301 |
| Drug interactions with HMG-CoA reductase inhibitors (statins): the importance of CYP enzymes, transporters and pharmacogenetics. | Current opinion in investigational drugs (London, England : 2000) 20100301 |
| Pitavastatin: a new HMG-CoA reductase inhibitor. | The Annals of pharmacotherapy 20100301 |
| Distribution of traditional and novel risk factors and their relation to subsequent cardiovascular events in patients with acute coronary syndromes (from the PROVE IT-TIMI 22 trial). | The American journal of cardiology 20100301 |
| Comparative study of low doses of rosuvastatin and atorvastatin on lipid and glycemic control in patients with metabolic syndrome and hypercholesterolemia. | The Korean journal of internal medicine 20100301 |
| Buccal drug delivery of pravastatin sodium. | AAPS PharmSciTech 20100301 |
| Pravastatin treatment before coronary artery bypass grafting for reduction of postoperative atrial fibrillation. | General thoracic and cardiovascular surgery 20100301 |
| Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome. | Current atherosclerosis reports 20100301 |
| Past, present and future therapeutics for cerebellar ataxias. | Current neuropharmacology 20100301 |
| Pravastatin treatment causes a shift in the balance of hippocampal neurotransmitter binding densities towards inhibition. | Brain research 20100226 |
| Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide. | Journal of immunology (Baltimore, Md. : 1950) 20100215 |
| Cholesterol reduction impairs exocytosis of synaptic vesicles. | Journal of cell science 20100215 |
| HMG-CoA reductase inhibitors (statins) activate expression of PPARalpha/PPARgamma and ABCA1 in cultured gallbladder epithelial cells. | Digestive diseases and sciences 20100201 |
| Is cyclosporine A transport inhibited by pravastatin via multidrug resistant protein 2? | European journal of clinical pharmacology 20100201 |
| Pravastatin use and cancer risk: a meta-analysis of individual patient data from long-term prospective controlled trials in Japan. | Pharmacoepidemiology and drug safety 20100201 |
| Investigation of the rate-determining process in the hepatic elimination of HMG-CoA reductase inhibitors in rats and humans. | Drug metabolism and disposition: the biological fate of chemicals 20100201 |
| In vitro interactions between primycin and different statins in their effects against some clinically important fungi. | Journal of medical microbiology 20100201 |
| Effects of walnut consumption on endothelial function in type 2 diabetic subjects: a randomized controlled crossover trial. | Diabetes care 20100201 |
| The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy. | The pharmacogenomics journal 20100201 |
| Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells. | American journal of physiology. Endocrinology and metabolism 20100201 |
| HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study. | European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20100201 |
| [A negative first-line work-up of Raynaud's phenomenon: And what if it were cancer?]. | Journal des maladies vasculaires 20100201 |
| Pravastatin counteracts angiotensin II-induced upregulation and activation of NADPH oxidase at plasma membrane of human endothelial cells. | Journal of cardiovascular pharmacology 20100201 |
| Effect of pravastatin on kidney function and urinary protein excretion in autosomal dominant polycystic kidney disease. | Scandinavian journal of urology and nephrology 20100201 |
| Beneficial microvascular and anti-inflammatory effects of pravastatin during sepsis involve nitric oxide synthase III. | British journal of anaesthesia 20100201 |
| Safety and tolerability of dalcetrapib (RO4607381/JTT-705): results from a 48-week trial. | European heart journal 20100201 |
| Relevance of conserved lysine and arginine residues in transmembrane helices for the transport activity of organic anion transporting polypeptide 1B3. | British journal of pharmacology 20100201 |
| Commentary on pravastatin and cancer: need for individual patient data meta-analyses. | Pharmacoepidemiology and drug safety 20100201 |
| Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk. | The American journal of medicine 20100201 |
| Vitamin E prevents steroid-induced osteonecrosis in rabbits. | Acta orthopaedica 20100201 |
| [Heparin-induced thrombocytopenia and disseminated intravascular coagulation in a patient with drug-induced pneumonia]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20100201 |
| Nicotinic acid + larodiorant. Laropiprant adds its own adverse effects. | Prescrire international 20100201 |
| Effect of preoperative statin therapy on myocardial protection and morbidity endpoints following off-pump coronary bypass surgery in patients with elevated C-reactive protein level. | Korean journal of anesthesiology 20100201 |
| Farnesyl pyrophosphate inhibits epithelialization and wound healing through the glucocorticoid receptor. | The Journal of biological chemistry 20100115 |
| Relation of change in apolipoprotein B/apolipoprotein A-I ratio to coronary plaque regression after Pravastatin treatment in patients with coronary artery disease. | The American journal of cardiology 20100115 |
| Tolerability of red yeast rice (2,400 mg twice daily) versus pravastatin (20 mg twice daily) in patients with previous statin intolerance. | The American journal of cardiology 20100115 |
| Rosuvastatin versus pravastatin in dyslipidemic HIV-1-infected patients receiving protease inhibitors: a randomized trial. | AIDS (London, England) 20100102 |
| Effects of pravastatin on serum osteoprotegerin levels in patients with hypercholesterolemia and type 2 diabetes. | Angiology 20100101 |
| Survival analysis using inverse probability of treatment weighted methods based on the generalized propensity score. | Pharmaceutical statistics 20100101 |
| Cholesterol absorption and synthesis markers in individuals with and without a CHD event during pravastatin therapy: insights from the PROSPER trial. | Journal of lipid research 20100101 |
| Pravastatin and cognitive function in the elderly. Results of the PROSPER study. | Journal of neurology 20100101 |
| Down-regulation of RhoA is involved in the cytotoxic action of lipophilic statins in HepG2 cells. | Atherosclerosis 20100101 |
| HPLC and mass spectrometry analysis of dolichol-phosphates at the cell culture scale. | Analytical biochemistry 20100101 |
| Biotechnological production and applications of statins. | Applied microbiology and biotechnology 20100101 |
| Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors. | European heart journal 20100101 |
| Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier. | Drug metabolism and disposition: the biological fate of chemicals 20100101 |
| A role of nitric oxide in neurite outgrowth of neuroblastoma cells triggered by mevastatin or serum reduction. | Neuroscience letters 20100101 |
| HIV-associated dyslipidaemia among HIV antibody-positive patients in Ireland: prevalence and management strategies. | International journal of STD & AIDS 20100101 |
| 11C-meta-hydroxyephedrine defects persist despite functional improvement in hibernating myocardium. | Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20100101 |
| Synergistic antifibrotic efficacy of statin and protein kinase C inhibitor in hepatic fibrosis. | American journal of physiology. Gastrointestinal and liver physiology 20100101 |
| Differing effect of statins on insulin sensitivity in non-diabetics: a systematic review and meta-analysis. | Diabetes research and clinical practice 20100101 |
| Effect of long- and short-term treatments with pravastatin on diabetes mellitus and pancreatic fibrosis in the Otsuka-Long-Evans-Tokushima fatty rat. | British journal of pharmacology 20100101 |
| Simvastatin does not affect vitamin d status, but low vitamin d levels are associated with dyslipidemia: results from a randomised, controlled trial. | International journal of endocrinology 20100101 |
| Does higher usage of low-cost statins correlate with a poorer achievement in cholesterol quality markers for secondary prevention? | The British journal of general practice : the journal of the Royal College of General Practitioners 20100101 |
| Standards of medical care in diabetes--2010. | Diabetes care 20100101 |
| The disposition of pravastatin in a rat model of streptozotocin-induced diabetes and organic anion transporting polypeptide 2 and multidrug resistance-associated protein 2 expression in the liver. | Biological & pharmaceutical bulletin 20100101 |
| Evaluating clinical periodontal measures as surrogates for bacterial exposure: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). | BMC medical research methodology 20100101 |
| A novel method to adjust efficacy estimates for uptake of other active treatments in long-term clinical trials. | PloS one 20100101 |
| Cloning, reassembling and integration of the entire nikkomycin biosynthetic gene cluster into Streptomyces ansochromogenes lead to an improved nikkomycin production. | Microbial cell factories 20100101 |
| Metabolism of a lipid nanoemulsion resembling low-density lipoprotein in patients with grade iii obesity. | Clinics (Sao Paulo, Brazil) 20100101 |
| Sex and ethnic differences in 47 candidate proteomic markers of cardiovascular disease: the Mayo Clinic proteomic markers of arteriosclerosis study. | PloS one 20100101 |
| MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1. | PloS one 20100101 |
| Efficacy and safety of ezetimibe for Japanese patients with dyslipidaemia: The ESSENTIAL Study. | Clinical drug investigation 20100101 |
| General practitioners' perceptions of the effectiveness of medical interventions: an exploration of underlying constructs. | Implementation science : IS 20100101 |
| Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract. | Nutrition & metabolism 20100101 |
| CCR2 and coronary artery disease: a woscops substudy. | BMC research notes 20100101 |
| Can statins prevent or help treat Alzheimer's disease? | Journal of Alzheimer's disease : JAD 20100101 |
| Effect of glitazones on the progression of coronary artery disease in type 2 diabetes patients. | Vascular health and risk management 20100101 |
| Cholesteryl ester transfer protein gene polymorphisms and longevity syndrome. | The open cardiovascular medicine journal 20100101 |
| TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies. | Arthritis research & therapy 20100101 |
| Variations in atherosclerosis and remodeling patterns in aorta and carotids. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20100101 |
| An alternative treatment of hyperlipidemia with red yeast rice: a case report. | Journal of medical case reports 20100101 |
| Association of repeatedly measured intermediate risk factors for complex diseases with high dimensional SNP data. | Algorithms for molecular biology : AMB 20100101 |
| Preadmission statin use and one-year mortality among patients in intensive care - a cohort study. | Critical care (London, England) 20100101 |
| Evaluation of different formulas for LDL-C calculation. | Lipids in health and disease 20100101 |
| Pre-hospital ECG for acute coronary syndrome in urban India: a cost-effectiveness analysis. | BMC cardiovascular disorders 20100101 |
| Current status and future directions in lipid management: emphasizing low-density lipoproteins, high-density lipoproteins, and triglycerides as targets for therapy. | Vascular health and risk management 20100101 |
| Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance. | BMC cancer 20100101 |
| The role of interleukin-18 in the metabolic syndrome. | Cardiovascular diabetology 20100101 |
| Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial. | BMJ (Clinical research ed.) 20100101 |
| Novel approaches to treat experimental pulmonary arterial hypertension: a review. | Journal of biomedicine & biotechnology 20100101 |
| Genome-wide association of lipid-lowering response to statins in combined study populations. | PloS one 20100101 |
| Associations between total cerebral blood flow and age related changes of the brain. | PloS one 20100101 |
| Semi-parametric risk prediction models for recurrent cardiovascular events in the LIPID study. | BMC medical research methodology 20100101 |
| HMG-CoA reductase inhibitors in kidney transplant recipients receiving tacrolimus: statins not associated with improved patient or graft survival. | BMC nephrology 20100101 |
| Statins Decrease Oxidative Stress and ICD Therapies. | Cardiology research and practice 20100101 |
| Atorvastatin in stroke: a review of SPARCL and subgroup analysis. | Vascular health and risk management 20100101 |
| A systematic review of clinical trials of pharmacological interventions for acute ischaemic stroke (1955-2008) that were completed, but not published in full. | Trials 20100101 |
| Statins and cognitive functioning in the elderly: a population-based study. | Journal of Alzheimer's disease : JAD 20100101 |
| A comprehensive molecular interaction map for rheumatoid arthritis. | PloS one 20100101 |
| Prevalence and risk factors of microalbuminuria in Thai nondiabetic hypertensive patients. | Vascular health and risk management 20100101 |
| Cardiovascular dementia - a different perspective. | The open biochemistry journal 20100101 |
| Age-Related Hypercholesterolemia and HMG-CoA Reductase Dysregulation: Sex Does Matter (A Gender Perspective). | Current gerontology and geriatrics research 20100101 |
| [Drug interaction caused by communication problems. Rhabdomyolysis due to a combination of itraconazole and simvastatin]. | Nederlands tijdschrift voor geneeskunde 20100101 |
| Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis. | BMC systems biology 20100101 |
| Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis. | Arthritis research & therapy 20100101 |
| A role for the mevalonate pathway in the induction of subtype cross-reactive immunity to influenza A virus by human gammadelta T lymphocytes. | Cellular immunology 20100101 |
| Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database. | BMJ (Clinical research ed.) 20100101 |
| Pitavastatin: the newest HMG-CoA reductase inhibitor. | Reviews in cardiovascular medicine 20100101 |
| Statin treatment and mortality in bacterial infections--a systematic review and meta-analysis. | PloS one 20100101 |
| How to translate therapeutic recommendations in clinical practice guidelines into rules for critiquing physician prescriptions? Methods and application to five guidelines. | BMC medical informatics and decision making 20100101 |
| Cyclic nucleotides and mitogen-activated protein kinases: regulation of simvastatin in platelet activation. | Journal of biomedical science 20100101 |
| Statins in candidemia: clinical outcomes from a matched cohort study. | BMC infectious diseases 20100101 |
| Lipid profile in consecutive pregnancies. | Lipids in health and disease 20100101 |
| Synergistic effect of simvastatin and ezetimibe on lipid and pro-inflammatory profiles in pre-diabetic subjects. | Diabetology & metabolic syndrome 20100101 |
| Methylthioadenosine (MTA) inhibits melanoma cell proliferation and in vivo tumor growth. | BMC cancer 20100101 |
| Fenofibric acid: a new fibrate approved for use in combination with statin for the treatment of mixed dyslipidemia. | Vascular health and risk management 20100101 |
| Lovastatin protects against experimental plague in mice. | PloS one 20100101 |
| Pdro, a protein associated with late endosomes and lysosomes and implicated in cellular cholesterol homeostasis. | PloS one 20100101 |
| Membrane plasmalogen composition and cellular cholesterol regulation: a structure activity study. | Lipids in health and disease 20100101 |
| Interleukin-17 regulation: an attractive therapeutic approach for asthma. | Respiratory research 20100101 |
| The CaaX specificities of Arabidopsis protein prenyltransferases explain era1 and ggb phenotypes. | BMC plant biology 20100101 |
| Use of evidence-based pharmacotherapy after myocardial infarction in Estonia. | BMC public health 20100101 |
| Pulmonary Embolism Mimicking Pneumonia in a HIV Patient. | Case reports in medicine 20100101 |
| Gene activation regresses atherosclerosis, promotes health, and enhances longevity. | Lipids in health and disease 20100101 |
| The HMG-CoA reductase inhibitor pravastatin stimulates insulin secretion through organic anion transporter polypeptides. | Drug metabolism and pharmacokinetics 20100101 |
| Use of statin therapy to reduce cardiovascular risk in older patients. | Current gerontology and geriatrics research 20100101 |
| Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus. | Mediators of inflammation 20100101 |
| Ezetimibe/simvastatin vs simvastatin in coronary heart disease patients with or without diabetes. | Lipids in health and disease 20100101 |
| Genomic characterization of large rearrangements of the LDLR gene in Czech patients with familial hypercholesterolemia. | BMC medical genetics 20100101 |
| Impact of medical therapy on atheroma volume measured by different cardiovascular imaging modalities. | Cardiology research and practice 20100101 |
| Unexplained Graft Dysfunction after Heart Transplantation-Role of Novel Molecular Expression Test Score and QTc-Interval: A Case Report. | Cardiology research and practice 20100101 |
| Leukocyte Count versus C-Reactive Protein Levels in Obese Portuguese Patients Aged 6-12 Years Old. | The open biochemistry journal 20100101 |
| Clinical implications of the cytokine hypothesis of depression: the association between use of statins and aspirin and the risk of major depression. | Psychotherapy and psychosomatics 20100101 |
| Pitavastatin: a new HMG-CoA reductase inhibitor for the treatment of hypercholesterolemia. | Cardiology in review 20100101 |
| The Role of Peroxisome Proliferator-Activated Receptor beta/delta on the Inflammatory Basis of Metabolic Disease. | PPAR research 20100101 |
| Atorvastatin pretreatment diminishes the levels of myocardial ischemia markers early after CABG operation: an observational study. | Journal of cardiothoracic surgery 20100101 |
| S-layer glycoproteins and flagellins: reporters of archaeal posttranslational modifications. | Archaea (Vancouver, B.C.) 20100101 |
| Comparison of four phaC genes from Haloferax mediterranei and their function in different PHBV copolymer biosyntheses in Haloarcula hispanica. | Saline systems 20100101 |
| Management of dyslipidemias with fibrates, alone and in combination with statins: role of delayed-release fenofibric acid. | Vascular health and risk management 20100101 |
| Statins: cost analysis in Indian scenario from eight major clinical trials. | Journal of postgraduate medicine 20100101 |
| Right man, right time, right place?--on the time course of the mediator orchestra in septic shock. | Critical care (London, England) 20100101 |
| Effects of pravastatin on cellular ultrastructure and hemorheology in rats after traumatic head injury. | Clinical hemorheology and microcirculation 20100101 |
| Sizing up stability: combination therapy with Apo-AI peptide mimetics and statins in systemic lupus erythematosus-mediated atherosclerosis. | Arthritis research & therapy 20100101 |
| Atherogenic dyslipidemia and diabetes mellitus: what's new in the management arena? | Vascular health and risk management 20100101 |
| Role of olmesartan in combination therapy in blood pressure control and vascular function. | Vascular health and risk management 20100101 |
| Treatment of cardiovascular risk factors to prevent cognitive decline and dementia: a systematic review. | Vascular health and risk management 20100101 |
| Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells. | PloS one 20100101 |
| Small artery elasticity is decreased in patients with systemic lupus erythematosus without increased intima media thickness. | Arthritis research & therapy 20100101 |
| Statins and clinical outcome of acute ischemic stroke: a systematic review. | International archives of medicine 20100101 |
| Renal protection in diabetes: lessons from ONTARGET. | Cardiovascular diabetology 20100101 |
| Rheumatoid arthritis patients receive less frequent acute reperfusion and secondary prevention therapy after myocardial infarction compared with the general population. | Arthritis research & therapy 20100101 |
| Benefits of statin therapy and compliance in high risk cardiovascular patients. | Vascular health and risk management 20100101 |
| The relationships of markers of cholesterol homeostasis with carotid intima-media thickness. | PloS one 20100101 |
| Drug interaction and pharmacist. | Journal of young pharmacists : JYP 20100101 |
| A new mouse model to explore therapies for preeclampsia. | PloS one 20100101 |
| Ezetimibe/simvastatin 10/20 mg versus rosuvastatin 10 mg in high-risk hypercholesterolemic patients stratified by prior statin treatment potency. | Lipids in health and disease 20100101 |
| Risk assessment and aspirin use in Asian and Western populations. | Vascular health and risk management 20100101 |
| Population based screening for chronic kidney disease: cost effectiveness study. | BMJ (Clinical research ed.) 20100101 |
| Pravastatin provides antioxidant activity and protection of erythrocytes loaded Primaquine. | International journal of medical sciences 20100101 |
| Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4. | Alzheimer's research & therapy 20100101 |
| Rosuvastatin promotes osteoblast differentiation and regulates SLCO1A1 transporter gene expression in MC3T3-E1 cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101 |
| Post-load hyperglycemia as an important predictor of long-term adverse cardiac events after acute myocardial infarction: a scientific study. | Cardiovascular diabetology 20100101 |
| Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition. | PloS one 20100101 |
| Niacin or ezetimibe for patients with, or at risk of coronary heart disease. | Clinical Medicine Insights. Cardiology 20100101 |
| Indirect comparisons: a review of reporting and methodological quality. | PloS one 20100101 |
| Hypercholesterolemia and microvascular dysfunction: interventional strategies. | Journal of inflammation (London, England) 20100101 |
| The cost effectiveness of statin therapies in Spain in 2010, after the introduction of generics and reference prices. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20100101 |
| Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston]. | BMC molecular biology 20100101 |
| Lipid control and use of lipid-regulating drugs for prevention of cardiovascular events in Chinese type 2 diabetic patients: a prospective cohort study. | Cardiovascular diabetology 20100101 |
| Clinical evaluation of Dyslipidemia among type II diabetic patients at Public hospital Penang, Malaysia. | International archives of medicine 20100101 |
| Synergic effect of eicosapentaenoic acid and lovastatin on gene expression of HMGCoA reductase and LDL receptor in cultured HepG2 cells. | Lipids in health and disease 20100101 |
| Are post-treatment low-density lipoprotein subclass pattern analyses potentially misleading? | Lipids in health and disease 20100101 |
| Combination therapy of statin and ezetimibe for the treatment of familial hypercholesterolemia. | Vascular health and risk management 20100101 |
| Computerized history-taking as a tool to manage dyslipidemia. | Vascular health and risk management 20100101 |
| Low high-density lipoprotein cholesterol: current status and future strategies for management. | Vascular health and risk management 20100101 |
| Pitavastatin approved for treatment of primary hypercholesterolemia and combined dyslipidemia. | Vascular health and risk management 20100101 |
| Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation. | PloS one 20100101 |
| Rosuvastatin reduces neointima formation in a rat model of balloon injury. | European journal of medical research 20100101 |
| Simvastatin impairs murine melanoma growth. | Lipids in health and disease 20100101 |
| Treatment of dyslipidemia in patients with type 2 diabetes. | Lipids in health and disease 20100101 |
| Data linkage: a powerful research tool with potential problems. | BMC health services research 20100101 |
| Lack of plasma albumin impairs intravascular lipolysis and explains the associated free fatty acids deficiency and hypertriglyceridemia. | Lipids in health and disease 20100101 |
| High density lipoproteins-based therapies for cardiovascular disease. | Journal of cardiovascular disease research 20100101 |
| Hyperhomocysteinemia is Associated with Aortic Atheroma Progression in Stroke/TIA Patients. | Frontiers in neurology 20100101 |
| Use of the Joint British Society cardiovascular risk calculator before initiating statins for primary prevention in hospital medicine: experience from a large university teaching hospital. | International journal of general medicine 20100101 |
| Combination of niacin extended-release and simvastatin results in a less atherogenic lipid profile than atorvastatin monotherapy. | Vascular health and risk management 20100101 |
| Optimal management of familial hypercholesterolemia: treatment and management strategies. | Vascular health and risk management 20100101 |
| Two siblings with familial chylomicronemia syndrome: disease course and effectiveness of early treatment. | Case reports in medicine 20100101 |
| Antiobesogenic and Antiatherosclerotic Properties of Caralluma fimbriata Extract. | Journal of nutrition and metabolism 20100101 |
| Drug-drug Interaction between Pravastatin and Gemfibrozil (Antihyperlipidemic) with Gliclazide (Antidiabetic) in Rats. | Journal of young pharmacists : JYP 20100101 |
| The role of RhoA/Rho kinase pathway in endothelial dysfunction. | Journal of cardiovascular disease research 20100101 |
| Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective. | Drug design, development and therapy 20100101 |
| Signaling of reactive oxygen and nitrogen species in Diabetes mellitus. | Oxidative medicine and cellular longevity 20100101 |
| Blocking protein farnesylation improves nuclear shape abnormalities in keratinocytes of mice expressing the prelamin A variant in Hutchinson-Gilford progeria syndrome. | Nucleus (Austin, Tex.) 20100101 |
| Quality of diabetes care at Armed Forces Hospital, Southern Region, Kingdom of Saudi Arabia, 2006. | Journal of family & community medicine 20100101 |
| Controversial data on simvastatin in asthma: What about the rat model? | Journal of asthma and allergy 20100101 |
| Pitavastatin: evidence for its place in treatment of hypercholesterolemia. | Core evidence 20100101 |
| Down-regulation of the global regulator SATB1 by statins in COLO205 colon cancer cells. | Molecular medicine reports 20100101 |
| Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems. | Cholesterol 20100101 |
| Randomized Trial of a Pharmacist-Delivered Intervention for Improving Lipid-Lowering Medication Adherence among Patients with Coronary Heart Disease. | Cholesterol 20100101 |
| [Evidence-based grounds of the efficacy of simvastatin (zocor): 15 years later]. | Terapevticheskii arkhiv 20100101 |
| Rosuvastatin counteracts vessel arterialisation and sinusoid capillarisation, reduces tumour growth, and prolongs survival in murine hepatocellular carcinoma. | Gastroenterology research and practice 20100101 |
| Cholesteryl ester transfer protein gene and effectiveness of lipid lowering of atorvastatin. | The open cardiovascular medicine journal 20100101 |
| Prevalence of modifiable cardiovascular risk factors in long-term renal transplant patients. | International journal of nephrology and renovascular disease 20100101 |
| A New Improved RP-HPLC Method for Assay of Rosuvastatin Calcium in Tablets. | Indian journal of pharmaceutical sciences 20100101 |
| Safety and efficacy of laropiprant and extended-release niacin combination in the management of mixed dyslipidemias and primary hypercholesterolemia. | Drug, healthcare and patient safety 20100101 |
| Intra-Laboratory Pre-Validation of a Human Cell Based in vitro Angiogenesis Assay for Testing Angiogenesis Modulators. | Frontiers in pharmacology 20100101 |
| Implications of genetic polymorphisms in inflammation-induced atherosclerosis. | The open cardiovascular medicine journal 20100101 |
| Atherothrombosis in South asians: implications of atherosclerotic and inflammatory markers. | The open cardiovascular medicine journal 20100101 |
| Screening of nutrient parameters for mevastatin production by Penicillium citrinum MTCC 1256 under submerged fermentation using the Plackett-Burman design. | Journal of pharmacy & bioallied sciences 20100101 |
| Endothelial function, blood pressure control, and risk modification: impact of irbesartan alone or in combination. | Integrated blood pressure control 20100101 |
| Impact of olmesartan on blood pressure, endothelial function, and cardiovascular outcomes. | Integrated blood pressure control 20100101 |
| Long-term treatment of patients with HIV-1: the role of atazanavir. | HIV/AIDS (Auckland, N.Z.) 20100101 |
| New and emerging agents in the management of lipodystrophy in HIV-infected patients. | HIV/AIDS (Auckland, N.Z.) 20100101 |
| Medicinal mushrooms: Towards a new horizon. | Pharmacognosy reviews 20100101 |
| The role of funding and policies on innovation in cancer drug development. | Ecancermedicalscience 20100101 |
| A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy. | Clinical pharmacology : advances and applications 20100101 |
| Individualized initiation of statin therapy determined by baseline LDL-C: Are you more likely to achieve goal LDL-C? | Risk management and healthcare policy 20100101 |
| Treatment of symptomatic HyperLp(a)lipoproteinemia with LDL-apheresis: a multicentre study. | Atherosclerosis. Supplements 20091229 |
| Reduction in recurrent cardiovascular events with intensive lipid-lowering statin therapy compared with moderate lipid-lowering statin therapy after acute coronary syndromes from the PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) trial. | Journal of the American College of Cardiology 20091215 |
| Cardiovascular outcomes in randomized trials: should time to first event for 'hard' end points remain the standard approach? | Journal of the American College of Cardiology 20091215 |
| Effect of intensive statin therapy on clinical outcomes among patients undergoing percutaneous coronary intervention for acute coronary syndrome. PCI-PROVE IT: A PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) Substudy. | Journal of the American College of Cardiology 20091208 |
| Endothelial function impairment in chronic venous insufficiency: effect of some cardiovascular protectant agents. | Angiology 20091201 |
| C-reactive protein in the very early phase of acute ischemic stroke: association with poor outcome and death. | Journal of neurology 20091201 |
| Fluvastatin and lovastatin inhibit granulocyte macrophage-colony stimulating factor-stimulated human eosinophil adhesion to inter-cellular adhesion molecule-1 under flow conditions. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091201 |
| Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT. | Diabetes 20091201 |
| Laboratory and non-laboratory-based risk prediction models for secondary prevention of cardiovascular disease: the LIPID study. | European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20091201 |
| Rediscovering bile acid sequestrants. | Diabetes, obesity & metabolism 20091201 |
| How do physicians conduct medication reviews? | Journal of general internal medicine 20091201 |
| SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. | Journal of the American Society of Nephrology : JASN 20091201 |
| Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP-1 cells, without decreasing the beneficial effects on cholesterol synthesis. | British journal of pharmacology 20091201 |
| Apolipoprotein e genotype, plasma cholesterol, and cancer: a Mendelian randomization study. | American journal of epidemiology 20091201 |
| The effect of exercise on serum levels of interleukin-18 and components of the metabolic syndrome. | Metabolic syndrome and related disorders 20091201 |
| HDL as a biomarker, potential therapeutic target, and therapy. | Diabetes 20091201 |
| Clinical significance of on-treatment triglyceride level in patients treated by percutaneous coronary intervention for non-ST-segment elevation acute coronary syndrome. | The Korean journal of internal medicine 20091201 |
| Coronary heart disease in moderately hypercholesterolemic, hypertensive black and non-black patients randomized to pravastatin versus usual care: the antihypertensive and lipid lowering to prevent heart attack trial (ALLHAT-LLT). | American heart journal 20091201 |
| Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells. | Nutrition research (New York, N.Y.) 20091201 |
| Statins: in the beginning. | The journal of the Royal College of Physicians of Edinburgh 20091201 |
| Atrial fibrillation at baseline and during follow-up in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial). | Journal of the American College of Cardiology 20091124 |
| In-vitro release kinetics and stability of anticardiovascular drugs-intercalated layered double hydroxide nanohybrids. | The journal of physical chemistry. B 20091112 |
| Compactin production studies using Penicillium brevicompactum under solid-state fermentation conditions. | Applied biochemistry and biotechnology 20091101 |
| Pravastatin prevents miscarriages in antiphospholipid antibody-treated mice. | Journal of reproductive immunology 20091101 |
| Phylogenetic analysis of Bacillus P450 monooxygenases and evaluation of their activity towards steroids. | Steroids 20091101 |
| Stimulation of artemisinin synthesis by combined cerebroside and nitric oxide elicitation in Artemisia annua hairy roots. | Applied microbiology and biotechnology 20091101 |
| Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. | Arteriosclerosis, thrombosis, and vascular biology 20091101 |
| The impact of pravastatin therapy on long-term outcome in patients with metabolic syndrome undergoing complete coronary revascularization. | Circulation journal : official journal of the Japanese Circulation Society 20091101 |
| Comparison of incidences of cardiovascular events among new users of different statins: a retrospective observational cohort study. | Current medical research and opinion 20091101 |
| Efavirenz: a decade of clinical experience in the treatment of HIV. | The Journal of antimicrobial chemotherapy 20091101 |
| Quantitative population pharmacokinetic analysis of pravastatin using an enterohepatic circulation model combined with pharmacogenomic Information on SLCO1B1 and ABCC2 polymorphisms. | Journal of clinical pharmacology 20091101 |
| Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins. | International journal of molecular medicine 20091101 |
| Effect of pravastatin on nephroprotection in deoxycorticosterone acetate-salt hypertensive rats. | Journal of hypertension 20091101 |
| Efficacy of aggressive lipid controlling therapy for preventing saphenous vein graft disease. | The Annals of thoracic surgery 20091101 |
| Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration. | Diabetes care 20091101 |
| Triglycerides and HDL cholesterol: stars or second leads in diabetes? | Diabetes care 20091101 |
| Should all diabetic patients be treated with a statin? | Diabetes care 20091101 |
| American Diabetes Association indications for statins in diabetes: is there evidence? | Diabetes care 20091101 |
| Obesity, hyperlipidemia, and metabolic syndrome. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091101 |
| Statins and colorectal cancer: the jury is still out. | The American journal of gastroenterology 20091101 |
| Chemistry and biosynthesis of isoprenylated flavonoids from Japanese mulberry tree. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20091101 |
| Socioeconomic inequalities in coronary heart disease risk in older age: contribution of established and novel coronary risk factors. | Journal of thrombosis and haemostasis : JTH 20091101 |
| Management of refractory essential thrombocythemia with anagrelide in a patient undergoing hemodialysis. | Clinical therapeutics 20091101 |
| Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20091028 |
| Complete reconstitution of a highly reducing iterative polyketide synthase. | Science (New York, N.Y.) 20091023 |
| The SLCO1B1*5 genetic variant is associated with statin-induced side effects. | Journal of the American College of Cardiology 20091020 |
| Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine. | The Journal of biological chemistry 20091016 |
| New highly sensitive enzyme immunoassay for the determination of pravastatin in human plasma. | Talanta 20091015 |
| Early statin therapy in acute coronary syndromes: the successful cycle of evidence, guidelines, and implementation. | Journal of the American College of Cardiology 20091006 |
| Skin ulcers and myopathy associated with pravastatin therapy. | Clinical and experimental dermatology 20091001 |
| Pravastatin and cardiovascular risk in moderate chronic kidney disease. | Atherosclerosis 20091001 |
| Differential effects of simvastatin and pravastatin on expression of Alzheimer's disease-related genes in human astrocytes and neuronal cells. | Journal of lipid research 20091001 |
| Low LDL cholesterol, albuminuria, and statins for the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry. | Diabetes care 20091001 |
| Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men. | Journal of thrombosis and haemostasis : JTH 20091001 |
| Suppression in mevalonate synthesis mediates antitumor effects of combined statin and gamma-tocotrienol treatment. | Lipids 20091001 |
| Prevention of contrast-induced nephropathy by chronic pravastatin treatment in patients with cardiovascular disease and renal insufficiency. | Journal of cardiology 20091001 |
| Statin therapy and risk of developing type 2 diabetes: a meta-analysis. | Diabetes care 20091001 |
| Statin-induced diabetes: will it change clinical practice? | Diabetes care 20091001 |
| Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin. | Pharmacogenomics 20091001 |
| Statins as antiarrhythmics: a systematic review part I: effects on risk of atrial fibrillation. | Clinical cardiology 20091001 |
| Assessing the effects of weather conditions on physical activity participation using objective measures. | International journal of environmental research and public health 20091001 |
| Hypolipidemic effects of Monascus-fermented soybean extracts in rats fed a high-fat and -cholesterol diet. | Journal of agricultural and food chemistry 20090923 |
| Risk factors for stroke and lipid-lowering effect of pravastatin on the risk of stroke in Japanese patients with hypercholesterolemia: analysis of data from the MEGA Study, a large randomized controlled trial. | Journal of the neurological sciences 20090915 |
| Effects of rosuvastatin on electronegative LDL as characterized by capillary isotachophoresis: the ROSARY Study. | Journal of lipid research 20090901 |
| The role of transporters in the pharmacokinetics of orally administered drugs. | Pharmaceutical research 20090901 |
| Characteristic changes in coronary artery at the early hyperglycaemic stage in a rat type 2 diabetes model and the effects of pravastatin. | British journal of pharmacology 20090901 |
| Chronic treatment with pravastatin prevents early cardiovascular changes in spontaneously hypertensive rats. | British journal of pharmacology 20090901 |
| Identification of genetic variants associated with response to statin therapy. | Arteriosclerosis, thrombosis, and vascular biology 20090901 |
| Seasonal variation in lipids: should we consider it more? | The American journal of cardiology 20090901 |
| The efficacy and safety of ezetimibe and low-dose simvastatin as a primary treatment for dyslipidemia in renal transplant recipients. | The Korean journal of internal medicine 20090901 |
| Rhabdomyolysis a result of azithromycin and statins: an unrecognized interaction. | British journal of clinical pharmacology 20090901 |
| The Vytorin on Carotid-Media Thickness and Overall Arterial Rigidity (VYCTOR) study. | Expert review of cardiovascular therapy 20090901 |
| Inflammatory markers and outcomes in cardiovascular disease. | PLoS medicine 20090901 |
| [Comparison on long-term effects of atorvastatin or pravastatin combined with clopidogrel for patients undergoing coronary stenting: a randomized controlled trial]. | Zhonghua yi xue za zhi 20090825 |
| Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies. | Blood 20090820 |
| Association of leukocyte subtype counts with coronary atherosclerotic regression following pravastatin treatment. | The American journal of cardiology 20090815 |
| A novel method for oral delivery of apolipoprotein mimetic peptides synthesized from all L-amino acids. | Journal of lipid research 20090801 |
| Circulating angiopoietin-2 in essential hypertension: relation to atherosclerosis, vascular inflammation, and treatment with olmesartan/pravastatin. | Journal of hypertension 20090801 |
| Improvement of glucose intolerance by combination of pravastatin and olmesartan in type II diabetic KK-A(y) mice. | Hypertension research : official journal of the Japanese Society of Hypertension 20090801 |
| Apolipoprotein B but not LDL cholesterol is associated with coronary artery calcification in type 2 diabetic whites. | Diabetes 20090801 |
| Pravastatin accelerates ischemia-induced angiogenesis through AMP-activated protein kinase. | Hypertension research : official journal of the Japanese Society of Hypertension 20090801 |
| Application of a 3,3-diphenylpentane skeleton as a multi-template for creation of HMG-CoA reductase inhibitors. | Bioorganic & medicinal chemistry letters 20090801 |
| Rationale and design of assessment of lipophilic vs. hydrophilic statin therapy in acute myocardial infarction (the ALPS-AMI) study. | Journal of cardiology 20090801 |
| Tissue distribution of mevalonate pyrophosphate decarboxylase in guinea pig. | Biological & pharmaceutical bulletin 20090801 |
| Effects of Xuezhikang and pravastatin on circulating endothelial progenitor cells in patients with essential hypertension. | Chinese journal of integrative medicine 20090801 |
| No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin. | British journal of clinical pharmacology 20090801 |
| Balancing potency of platelet inhibition with bleeding risk in the early treatment of acute coronary syndrome. | The western journal of emergency medicine 20090801 |
| [Effects of pravastatin and granulocyto-colony stimulating factor in mobilizing endothelial progenitor cells in mice with myocardial ischemia]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090801 |
| Rosuvastatin for cardiovascular prevention: too many uncertainties. | Prescrire international 20090801 |
| Influence of grapefruit juice on the pharmacokinetics of diltiazem in Wistar rats upon single and multiple dosage regimens. | Die Pharmazie 20090801 |
| Interventions in the management of serum lipids for preventing stroke recurrence. | The Cochrane database of systematic reviews 20090708 |
| Rosuvastatin reduces atherosclerotic lesions and promotes progenitor cell mobilisation and recruitment in apolipoprotein E knockout mice. | Atherosclerosis 20090701 |
| A randomized, multicentre, open-label, parallel-group trial to compare the efficacy and safety profile of daming capsule in patients with hypercholesterolemia. | Phytotherapy research : PTR 20090701 |
| Mevastatin-induced neurite outgrowth of neuroblastoma cells via activation of EGFR. | Journal of neuroscience research 20090701 |
| Prevalence of microalbuminuria and associated electrocardiographic abnormalities in an Indo-Asian population. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701 |
| Oral pravastatin prolongs survival time of scrapie-infected mice. | The Journal of general virology 20090701 |
| Additive interaction between the renin-angiotensin system and lipid metabolism for cancer in type 2 diabetes. | Diabetes 20090701 |
| Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people. | European heart journal 20090701 |
| Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development. | Hepatology (Baltimore, Md.) 20090701 |
| Statins inhibit the growth of variant human embryonic stem cells and cancer cells in vitro but not normal human embryonic stem cells. | British journal of pharmacology 20090701 |
| The VYtorin on Carotid intima-media thickness and overall arterial rigidity (VYCTOR) study. | Journal of clinical pharmacology 20090701 |
| Effects of combined olmesartan and pravastatin on glucose intolerance and cardiovascular remodeling in a metabolic-syndrome model. | Hypertension research : official journal of the Japanese Society of Hypertension 20090701 |
| Combination treatment to prevent atherosclerosis. | Hypertension (Dallas, Tex. : 1979) 20090701 |
| Low HDL cholesterol is associated with the risk of stroke in elderly diabetic individuals: changes in the risk for atherosclerotic diseases at various ages. | Diabetes care 20090701 |
| Safety and tolerability of dalcetrapib. | The American journal of cardiology 20090701 |
| Long-term efficacy of upstream therapy using angiotensin-converting enzyme inhibitors and statins in combination with antiarrhythmic agents for the treatment of paroxysmal atrial fibrillation. | International heart journal 20090701 |
| Effect of precultural and nutritional parameters on compactin production by solid-state fermentation. | Journal of microbiology and biotechnology 20090701 |
| [Simvastatin-induced dermatomyositis]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20090601 |
| Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients. | Atherosclerosis 20090601 |
| Heterologous expression, purification, and characterization of cytochrome P450sca-2 and mutants with improved solubility in Escherichia coli. | Protein expression and purification 20090601 |
| Functional analysis of a mutation in the SLCO1B1 gene (c.1628T>G) identified in a Japanese patient with pravastatin-induced myopathy. | The pharmacogenomics journal 20090601 |
| Effect of bile acids on the biliary excretion of pravastatin in rats. | Hepatology research : the official journal of the Japan Society of Hepatology 20090601 |
| Effects of rosuvastatin and atorvastatin on LDL and HDL particle concentrations in patients with metabolic syndrome: a randomized, double-blind, controlled study. | Diabetes care 20090601 |
| MlcR, a zinc cluster activator protein, is able to bind to a single (A/T)CGG site of cognate asymmetric motifs in the ML-236B (compactin) biosynthetic gene cluster. | Molecular genetics and genomics : MGG 20090601 |
| Improvement of compactin (ML-236B) production by genetic engineering in compactin high-producing Penicillium citrinum. | Applied microbiology and biotechnology 20090601 |
| Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease. | Neurobiology of disease 20090601 |
| Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1. | Experimental biology and medicine (Maywood, N.J.) 20090601 |
| [Effect of intensive treatment with atorvastatin versus standard doses of statins on the risk of stroke. A meta-analysis from five randomized trials including 25,709 patients]. | Revista de neurologia 20090601 |
| Conversion to tacrolimus and atorvastatin in cyclosporine-treated heart transplant recipients with dyslipidemia refractory to fluvastatin. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601 |
| Pleiotropic phenotypes caused by an opal nonsense mutation in an essential gene encoding HMG-CoA reductase in fission yeast. | Genes to cells : devoted to molecular & cellular mechanisms 20090601 |
| Established and newly proposed mechanisms of chronic cyclosporine nephropathy. | The Korean journal of internal medicine 20090601 |
| Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? | PLoS medicine 20090601 |
| Association of body mass index with coronary plaque regression: 6-month prospective study. | Journal of atherosclerosis and thrombosis 20090601 |
| Effects of a concomitant single oral dose of rifampicin on the pharmacokinetics of pravastatin in a two-phase, randomized, single-blind, placebo-controlled, crossover study in healthy Chinese male subjects. | Clinical therapeutics 20090601 |
| Adenosine and adenosine receptors: Newer therapeutic perspective. | Indian journal of pharmacology 20090601 |
| Effect of intensive lipid-lowering therapy on telomere erosion in endothelial progenitor cells obtained from patients with coronary artery disease. | Clinical science (London, England : 1979) 20090501 |
| Pravastatin limits radiation-induced vascular dysfunction in the skin. | The Journal of investigative dermatology 20090501 |
| PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients. | Diabetes care 20090501 |
| Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. | Diabetes care 20090501 |
| Digoxin and ouabain increase the synthesis of cholesterol in human liver cells. | Cellular and molecular life sciences : CMLS 20090501 |
| Fluvastatin improves osteoporosis in fructose-fed insulin resistant model rats through blockade of the classical mevalonate pathway and antioxidant action. | International journal of molecular medicine 20090501 |
| Complete blockage of the mevalonate pathway results in male gametophyte lethality. | Journal of experimental botany 20090501 |
| Effect of atorvastatin on microRNA 221 / 222 expression in endothelial progenitor cells obtained from patients with coronary artery disease. | European journal of clinical investigation 20090501 |
| The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study. | Pharmacogenetics and genomics 20090501 |
| Re: Statin-induced bone morphogenetic protein (BMP) 2 expression during bone regeneration: an immunohistochemical study. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20090501 |
| Effect of procainization of ventromedial nucleus of hypothalamus on the feeding behavior of rats. | Journal of clinical biochemistry and nutrition 20090501 |
| Rhabdomyolysis in an HIV-infected patient on anti-retroviral therapy precipitated by high-dose pravastatin. | Current drug safety 20090501 |
| Managing toxicities and optimal dosing of targeted drugs in advanced kidney cancer. | Current oncology (Toronto, Ont.) 20090501 |
| Asymmetric dimethylarginine (ADMA) and endothelial dysfunction: implications for atherogenesis. | Clinics (Sao Paulo, Brazil) 20090501 |
| Trypanosoma cruzi: participation of cholesterol and placental alkaline phosphatase in the host cell invasion. | Experimental parasitology 20090501 |
| Effect of R219K polymorphism of the ABCA1 gene on the lipid-lowering effect of pravastatin in Chinese patients with coronary heart disease. | Clinical and experimental pharmacology & physiology 20090501 |
| Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury. | Blood 20090423 |
| Efficient biotransformations using Escherichia coli with tolC acrAB mutations expressing cytochrome P450 genes. | Bioscience, biotechnology, and biochemistry 20090423 |
| Seasonal variation in lipids in patients following acute coronary syndrome on fixed doses of Pravastatin (40 mg) or Atorvastatin (80 mg) (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22 [PROVE IT-TIMI 22] Study). | The American journal of cardiology 20090415 |
| Statins for the prevention of dementia. | The Cochrane database of systematic reviews 20090415 |
| Pravastatin attenuates interferon-gamma action via modulation of STAT1 to prevent aortic atherosclerosis in apolipoprotein E-knockout mice. | Clinical and experimental pharmacology & physiology 20090401 |
| The synergistic inhibition of atherogenesis in apoE-/- mice between pravastatin and the sPLA2 inhibitor varespladib (A-002). | Journal of lipid research 20090401 |
| C-reactive protein and 5-year survival in type 2 diabetes: the Casale Monferrato Study. | Diabetes 20090401 |
| Statin therapy is associated with lower total but not bioavailable or free testosterone in men with type 2 diabetes. | Diabetes care 20090401 |
| Alanine aminotransferase, gamma-glutamyltransferase, and incident diabetes: the British Women's Heart and Health Study and meta-analysis. | Diabetes care 20090401 |
| A test of the lipostat theory in a seasonal (ovine) model under natural conditions reveals a close relationship between adiposity and melanin concentrating hormone expression. | Domestic animal endocrinology 20090401 |
| Rhabdomyolysis reports show interaction between simvastatin and CYP3A4 inhibitors. | Pharmacoepidemiology and drug safety 20090401 |
| Antihypertensive therapy, new-onset diabetes, and cardiovascular disease. | International journal of clinical practice 20090401 |
| Preoperative statin use and infection after cardiac surgery: a cohort study. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090401 |
| Statins may not protect against vasospasm in subarachnoid haemorrhage. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090401 |
| Potentiated cytotoxic effects of statins and ajoene in murine melanoma cells. | Melanoma research 20090401 |
| Towards prediction of metabolic products of polyketide synthases: an in silico analysis. | PLoS computational biology 20090401 |
| Personalized medicine in coronary artery disease: insights from genomic research. | Korean circulation journal 20090401 |
| Rosuvastatin in patients with elevated C-reactive protein. | The New England journal of medicine 20090305 |
| Effects of pravastatin on functional capacity in patients with chronic obstructive pulmonary disease and pulmonary hypertension. | Clinical science (London, England : 1979) 20090301 |
| Role of pravastatin in pulmonary hypertension in chronic obstructive pulmonary disease. | Clinical science (London, England : 1979) 20090301 |
| Use of sandwich-cultured human hepatocytes to predict biliary clearance of angiotensin II receptor blockers and HMG-CoA reductase inhibitors. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA. | American journal of physiology. Cell physiology 20090301 |
| Prognostic utility of apoB/AI, total cholesterol/HDL, non-HDL cholesterol, or hs-CRP as predictors of clinical risk in patients receiving statin therapy after acute coronary syndromes: results from PROVE IT-TIMI 22. | Arteriosclerosis, thrombosis, and vascular biology 20090301 |
| Metabolic syndrome abating the beneficial effect of pravastatin treatment on adhesion of endothelium by monocytes in subjects with hypercholesterolemia. | Metabolism: clinical and experimental 20090301 |
| Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo. | Journal of cell communication and signaling 20090301 |
| The carotenogenesis pathway via the isoprenoid-beta-carotene interference approach in a new strain of Dunaliella salina isolated from Baja California Mexico. | Marine drugs 20090301 |
| [Atorvastatin in secondary prevention]. | Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20090301 |
| Mevinolin enhances osteogenic genes (ALP, type I collagen and osteocalcin), CD44, CD47 and CD51 expression during osteogenic differentiation. | Life sciences 20090227 |
| [Statin therapy and muscle disorders]. | Orvosi hetilap 20090208 |
| [Comment from the cardiologic viewpoint]. | Praxis 20090204 |
| 3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090204 |
| Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation. | Osteoarthritis and cartilage 20090201 |
| Pitfalls in the design and analysis of paediatric clinical trials: a case of a 'failed' multi-centre study, and potential solutions. | Acta paediatrica (Oslo, Norway : 1992) 20090201 |
| Adipocytokines and risk of stroke in older people: a nested case-control study. | International journal of epidemiology 20090201 |
| Effects of high-dose simvastatin therapy on glucose metabolism and ectopic lipid deposition in nonobese type 2 diabetic patients. | Diabetes care 20090201 |
| Physiologically based pharmacokinetic modeling to predict transporter-mediated clearance and distribution of pravastatin in humans. | The Journal of pharmacology and experimental therapeutics 20090201 |
| Leptin predicts diabetes but not cardiovascular disease: results from a large prospective study in an elderly population. | Diabetes care 20090201 |
| Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. | Diabetologia 20090201 |
| Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors. | Circulation journal : official journal of the Japanese Circulation Society 20090201 |
| Fate and distribution of pharmaceuticals in wastewater and sewage sludge of the conventional activated sludge (CAS) and advanced membrane bioreactor (MBR) treatment. | Water research 20090201 |
| Pravastatin for cardiovascular event primary prevention in patients with mild-to-moderate hypertension in the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA) Study. | Hypertension (Dallas, Tex. : 1979) 20090201 |
| Treatment with statin on atheroma regression evaluated by intravascular ultrasound with Virtual Histology (TRUTH Study): rationale and design. | Circulation journal : official journal of the Japanese Circulation Society 20090201 |
| Effects of pravastatin on the function of dendritic cells in patients with coronary heart disease. | Basic & clinical pharmacology & toxicology 20090201 |
| Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response. | Pharmacogenetics and genomics 20090201 |
| Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia? | Metabolism: clinical and experimental 20090201 |
| Controversial role of plant sterol esters in the management of hypercholesterolaemia. | European heart journal 20090201 |
| [Pharmacogenomics: inter-ethnic and intra-ethnic differences in pharmacokinetic and pharmacodynamic profiles of clinically relevant drugs]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090201 |
| Perceived medication adverse effects and coping strategies reported by chronic heart failure patients. | International journal of clinical practice 20090201 |
| Co-medication of statins and CYP3A4 inhibitors before and after introduction of new reimbursement policy. | British journal of clinical pharmacology 20090201 |
| The relationship between reduction in low-density lipoprotein cholesterol by statins and reduction in risk of cardiovascular outcomes: an updated meta-analysis. | Clinical therapeutics 20090201 |
| The effect of dyslipidemic drugs on mortality: A meta-analysis. | Indian journal of pharmacology 20090201 |
| Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle. | Circulation research 20090130 |
| The cornucopia of 'pleiotropic' actions of statins: myogenesis as a new mechanism for statin-induced benefits? | Circulation research 20090130 |
| No effect of statins on biochemical outcomes after radiotherapy for localized prostate cancer. | Urology 20090101 |
| Pravastatin, a 3-hydroxy-3-methyl-glutharyl coenzyme A inhibitor does not show pleiotropic effects in patients with systemic lupus erythematosus. | Rheumatology international 20090101 |
| Statin-induced bone morphogenetic protein (BMP) 2 expression during bone regeneration: an immunohistochemical study. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20090101 |
| Statin ameliorates hypoxia-induced pulmonary hypertension associated with down-regulated stromal cell-derived factor-1. | Cardiovascular research 20090101 |
| Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20090101 |
| Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung. | Thorax 20090101 |
| Statins alter neutrophil migration by modulating cellular Rho activity--a potential mechanism for statins-mediated pleotropic effects? | Journal of leukocyte biology 20090101 |
| Clopidogrel: review of bioanalytical methods, pharmacokinetics/pharmacodynamics, and update on recent trends in drug-drug interaction studies. | Biomedical chromatography : BMC 20090101 |
| Aspergillus westerdijkiae polyketide synthase gene 'aoks1' is involved in the biosynthesis of ochratoxin A. | Fungal genetics and biology : FG & B 20090101 |
| Complete assignment of 1H and 13C NMR data of pravastatin derivatives. | Magnetic resonance in chemistry : MRC 20090101 |
| Leptin, but not adiponectin, is a predictor of recurrent cardiovascular events in men: results from the LIPID study. | International journal of obesity (2005) 20090101 |
| Trends in the use of lipid-lowering medications at discharge in patients with acute myocardial infarction: 1998 to 2006. | American heart journal 20090101 |
| Competitive substrates for P-glycoprotein and organic anion protein transporters differentially reduce blood organ transport of fentanyl and loperamide: pharmacokinetics and pharmacodynamics in Sprague-Dawley rats. | Anesthesia and analgesia 20090101 |
| The effects of Thiazolidinediones on metabolic complications and Lipodystrophy in HIV-infected patients. | PPAR research 20090101 |
| Standards of medical care in diabetes--2009. | Diabetes care 20090101 |
| [Effect of the brand and generic medicine of pravastatin on dyslipidemia in rabbits fed a high cholesterol diet]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090101 |
| Possible mechanisms underlying statin-induced skeletal muscle toxicity in L6 fibroblasts and in rats. | Journal of pharmacological sciences 20090101 |
| Use of Framingham risk score and new biomarkers to predict cardiovascular mortality in older people: population based observational cohort study. | BMJ (Clinical research ed.) 20090101 |
| Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. | BMC medical genomics 20090101 |
| The plastidial 2-C-methyl-D-erythritol 4-phosphate pathway provides the isoprenyl moiety for protein geranylgeranylation in tobacco BY-2 cells. | The Plant cell 20090101 |
| Atorvastatin ameliorates cerebral vasospasm and early brain injury after subarachnoid hemorrhage and inhibits caspase-dependent apoptosis pathway. | BMC neuroscience 20090101 |
| Reduced glomerular filtration rate and its association with clinical outcome in older patients at risk of vascular events: secondary analysis. | PLoS medicine 20090101 |
| An account of cloned genes of Methyl-erythritol-4-phosphate pathway of isoprenoid biosynthesis in plants. | Current issues in molecular biology 20090101 |
| Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis. | BMJ (Clinical research ed.) 20090101 |
| A-002 (Varespladib), a phospholipase A2 inhibitor, reduces atherosclerosis in guinea pigs. | BMC cardiovascular disorders 20090101 |
| [Primary prevention trial by lowering hyperlipidemia on the cardiovascular disease (MEGA Study)]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20090101 |
| In vitro-in vivo extrapolation of transporter-mediated clearance in the liver and kidney. | Drug metabolism and pharmacokinetics 20090101 |
| Neural differentiation potential of human bone marrow-derived mesenchymal stromal cells: misleading marker gene expression. | BMC neuroscience 20090101 |
| Effects of statins on the secretion of human serum albumin in cultured HepG2 cells. | Journal of biomedical science 20090101 |
| Rosuvastatin-induced rhabdomyolysis probably via CYP2C9 saturation. | Drug metabolism and drug interactions 20090101 |
| Lifestyle-induced metabolic inflexibility and accelerated ageing syndrome: insulin resistance, friend or foe? | Nutrition & metabolism 20090101 |
| Sociodemographic variations in the contribution of secondary drug prevention to stroke survival at middle and older ages: cohort study. | BMJ (Clinical research ed.) 20090101 |
| Identification, expression, and functional characterization of full-length and splice variants of murine organic anion transporting polypeptide 1b2. | Molecular pharmaceutics 20090101 |
| Impact of ezetimibe on cholesterol subfractions in dyslipidemic cardiac transplant recipients receiving statin therapy. | Clinical transplantation 20090101 |
| OxDBase: a database of oxygenases involved in biodegradation. | BMC research notes 20090101 |
| Evidence synthesis as the key to more coherent and efficient research. | BMC medical research methodology 20090101 |
| Atorvastatin reduces plasma levels of chemokine (CXCL10) in patients with Crohn's disease. | PloS one 20090101 |
| Ten-Year Survival in 75-Year-Old Men and Women: Predictive Ability of Total Cholesterol, HDL-C, and LDL-C. | Current gerontology and geriatrics research 20090101 |
| Role of atazanavir in the treatment of HIV infection. | Therapeutics and clinical risk management 20090101 |
| Efficacy and safety of rosuvastatin in the management of dyslipidemia. | Vascular health and risk management 20090101 |
| Prevention of atherosclerosis in patients living with HIV. | Vascular health and risk management 20090101 |
| Management of complex lipid abnormalities with a fixed dose combination of simvastatin and extended release niacin. | Vascular health and risk management 20090101 |
| The effect of angiotensin receptor blockers on C-reactive protein and other circulating inflammatory indices in man. | Vascular health and risk management 20090101 |
| Dyslipidemia treatment of patients with diabetes mellitus in a US managed care plan: a retrospective database analysis. | Cardiovascular diabetology 20090101 |
| Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately? | The open neurology journal 20090101 |
| Efficacy, effectiveness and real life goal attainment of statins in managing cardiovascular risk. | Vascular health and risk management 20090101 |
| Fixed combination of amlodipine and atorvastatin in cardiovascular risk management: patient perspectives. | Vascular health and risk management 20090101 |
| Impact of statins and ACE inhibitors on mortality after COPD exacerbations. | Respiratory research 20090101 |
| ACE (I/D) polymorphism and response to treatment in coronary artery disease: a comprehensive database and meta-analysis involving study quality evaluation. | BMC medical genetics 20090101 |
| Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cells. | PloS one 20090101 |
| The biosynthesis and accumulation of beta-carotene in Dunaliella salina proceed via the glyceraldehyde 3-phosphate/pyruvate pathway. | Natural product research 20090101 |
| Statins and erectile dysfunction: results of a case/non-case study using the French Pharmacovigilance System Database. | Drug safety 20090101 |
| Statin use and risk of community acquired pneumonia in older people: population based case-control study. | BMJ (Clinical research ed.) 20090101 |
| Prevalence of transcription promoters within archaeal operons and coding sequences. | Molecular systems biology 20090101 |
| Antiretroviral effect of lovastatin on HIV-1-infected individuals without highly active antiretroviral therapy (The LIVE study): a phase-II randomized clinical trial. | Trials 20090101 |
| Reducing morbidity and mortality in high risk patients with statins. | Vascular health and risk management 20090101 |
| Treatment of pediatric pulmonary hypertension. | Vascular health and risk management 20090101 |
| The link between human and transgenic animal studies involving postprandial hypertriglyceridemia and CETP gene polymorphisms. | The open cardiovascular medicine journal 20090101 |
| Implementation of guidelines for the management of arterial hypertension. The impulsion study. | The open cardiovascular medicine journal 20090101 |
| Effects of cardiovascular lifestyle change on lipoprotein subclass profiles defined by nuclear magnetic resonance spectroscopy. | Lipids in health and disease 20090101 |
| The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials. | BMJ (Clinical research ed.) 20090101 |
| Kidney function and estimated vascular risk in patients with primary dyslipidemia. | The open cardiovascular medicine journal 20090101 |
| Pleiotropic effects of statins in atrial fibrillation patients: the evidence. | Vascular health and risk management 20090101 |
| Associations between statins and COPD: a systematic review. | BMC pulmonary medicine 20090101 |
| Statin-induced calcification in human mesenchymal stem cells is cell death related. | Journal of cellular and molecular medicine 20090101 |
| Effect of rosiglitazone on progression of atherosclerosis: insights using 3D carotid cardiovascular magnetic resonance. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101 |
| Regulation of bile acid and cholesterol metabolism by PPARs. | PPAR research 20090101 |
| New options in the treatment of lipid disorders in HIV-infected patients. | The open AIDS journal 20090101 |
| Characteristics, management and attainment of lipid target levels in diabetic and cardiac patients enrolled in Disease Management Program versus those in routine care: LUTZ registry. | BMC public health 20090101 |
| Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. | Interdisciplinary perspectives on infectious diseases 20090101 |
| Managing treatment-experienced pediatric and adolescent HIV patients: role of darunavir. | Therapeutics and clinical risk management 20090101 |
| RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension. | Vascular health and risk management 20090101 |
| Mood stabilizer therapy and pravastatin: higher risk for adverse skin reactions? | Acta medica (Hradec Kralove) 20090101 |
| Conjugated linoleic acids as functional food: an insight into their health benefits. | Nutrition & metabolism 20090101 |
| Lipoprotein ratios: Physiological significance and clinical usefulness in cardiovascular prevention. | Vascular health and risk management 20090101 |
| Antiatherogenic effects of vitamin E: the search for the Holy Grail. | Vascular health and risk management 20090101 |
| Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
| An editor for pathway drawing and data visualization in the Biopathways Workbench. | BMC systems biology 20090101 |
| Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk. | Vascular health and risk management 20090101 |
| Apoptosis of lens epithelial cells induced by high concentration of glucose is associated with a decrease in caveolin-1 levels. | Molecular vision 20090101 |
| Statin prophylaxis and inflammatory mediators following cardiopulmonary bypass: a systematic review. | Critical care (London, England) 20090101 |
| Effects of increasing the dose of pravastatin on serum adiponectin level in Japanese mild hypercholesterolemic and hypertensive patients. | Arzneimittel-Forschung 20090101 |
| Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis. | BMC medical genetics 20090101 |
| The impact of statins on health services utilization and mortality in older adults discharged from hospital with ischemic heart disease: a cohort study. | BMC health services research 20090101 |
| Long-term prediction of fish growth under varying ambient temperature using a multiscale dynamic model. | BMC systems biology 20090101 |
| Pleiotropic vasoprotective effects of statins: the chicken or the egg? | Drug design, development and therapy 20090101 |
| Hypercholesterolemia and myocardial function evaluated via tissue doppler imaging. | Cardiovascular ultrasound 20090101 |
| Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease. | Lipids in health and disease 20090101 |
| Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles. | PloS one 20090101 |
| Influenza morbidity and mortality in elderly patients receiving statins: a cohort study. | PloS one 20090101 |
| Management of dyslipidemia in children. | Diabetology & metabolic syndrome 20090101 |
| Critical appraisal of the role of pitavastatin in treating dyslipidemias and achieving lipid goals. | Vascular health and risk management 20090101 |
| [Achievement of blood lipid target levels with Ezetimibe/Simvastatin in patients with atherosclerosis and/or diabetes mellitus--an Austrian observational study]. | Wiener medizinische Wochenschrift (1946) 20090101 |
| Universal health care no guarantee of equity: comparison of socioeconomic inequalities in the receipt of coronary procedures in patients with acute myocardial infarction and angina. | BMC public health 20090101 |
| SWiss Atorvastatin and interferon Beta-1b trial In Multiple Sclerosis (SWABIMS)--rationale, design and methodology. | Trials 20090101 |
| Cardiovascular magnetic resonance in carotid atherosclerotic disease. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20090101 |
| Statin research in critical illness: hampered by poor trial design? | Critical care (London, England) 20090101 |
| Comparison of the efficacy of administering a combination of ezetimibe plus fenofibrate versus atorvastatin monotherapy in the treatment of dyslipidemia. | Lipids in health and disease 20090101 |
| Adolescent type 1 Diabetes Cardio-renal Intervention Trial (AdDIT). | BMC pediatrics 20090101 |
| An electronic clinical decision support tool to assist primary care providers in cardiovascular disease risk management: development and mixed methods evaluation. | Journal of medical Internet research 20090101 |
| Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. | PloS one 20090101 |
| Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3. | PloS one 20090101 |
| The JUPITER and AURORA clinical trials for rosuvastatin in special primary prevention populations: perspectives, outcomes, and consequences. | Vascular health and risk management 20090101 |
| Nitric oxide and coronary vascular endothelium adaptations in hypertension. | Vascular health and risk management 20090101 |
| Norepinephrine transporter is involved in down-regulation of beta1-adrenergic receptors caused by adjuvant arthritis. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101 |
| Pharmacogenomic insights into treatment and management of statin-induced myopathy. | Genome medicine 20090101 |
| A Multidisciplinary Investigation to Determine the Structure and Source of Dimeric Impurities in AMG 517 Drug Substance. | International journal of analytical chemistry 20090101 |
| A comparative evaluation of safety and efficacy of rosuvastatin, simvastatin, and atorvastatin in patients of type 2 diabetes mellitus with dyslipidemia. | International journal of diabetes in developing countries 20090101 |
| A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study. | Journal of the American Society of Hypertension : JASH 20090101 |
| Epidemiologic characteristics and risk factors for renal cell cancer. | Clinical epidemiology 20090101 |
| New oral disease-modifying therapies for multiple sclerosis. | F1000 medicine reports 20090101 |
| Improving glycemic and cholesterol control through an integrated approach incorporating colesevelam - a clinical perspective. | Diabetes, metabolic syndrome and obesity : targets and therapy 20090101 |
| The use of everolimus in renal-transplant patients. | International journal of nephrology and renovascular disease 20090101 |
| Long-term use of rosuvastatin: a critical risk benefit appraisal and comparison with other antihyperlipidemics. | Drug, healthcare and patient safety 20090101 |
| Improvement in sleep apnoea associated with switch from simvastatin to pravastatin. | BMJ case reports 20090101 |
| Effects of antihypertensive drugs on carotid intima-media thickness: Focus on angiotensin II receptor blockers. A review of randomized, controlled trials. | Integrated blood pressure control 20090101 |
| Safety and efficacy of statin therapy in patients switched from cyclosporine a to sirolimus after cardiac transplantation. | Transplantation 20081227 |
| Berberine decreases PCSK9 expression in HepG2 cells. | Atherosclerosis 20081201 |
| Reduction of charge-modified LDL by statin therapy in patients with CHD or CHD risk factors and elevated LDL-C levels: the SPECIAL Study. | Atherosclerosis 20081201 |
| Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer. | Cancer science 20081201 |
| Does low to moderate alcohol intake protect against cognitive decline in older people? | Journal of the American Geriatrics Society 20081201 |
| Tolerability and effects on lipids of ezetimibe coadministered with pravastatin or simvastatin for twelve months: results from two open-label extension studies in hypercholesterolemic patients. | Clinical therapeutics 20081201 |
| Managing hypercholesterolemia and its correlation with carotid plaque morphology in patients undergoing carotid endarterectomy. | Vascular health and risk management 20081201 |
| Achieving lipid goals with rosuvastatin compared with simvastatin in high risk patients in real clinical practice: a randomized, open-label, parallel-group, multi-center study: the DISCOVERY-Beta study. | Vascular health and risk management 20081201 |
| Dysfunctional regulation of ocular blood flow: A risk factor for glaucoma? | Clinical ophthalmology (Auckland, N.Z.) 20081201 |
| Pharmacogenetic predictors of statin-mediated low-density lipoprotein cholesterol reduction and dose response. | Circulation. Cardiovascular genetics 20081201 |
| Rosuvastatin reduces non-high-density lipoprotein cholesterol and lipoprotein remnants in patients with dysbetalipoproteinemia (Fredrickson type III hyperlipoproteinemia). | Journal of clinical lipidology 20081201 |
| Concomitant use of statins and CYP3A4 inhibitors in administrative claims and electronic medical records databases. | Journal of clinical lipidology 20081201 |
| Primary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patients. | Journal of the American College of Cardiology 20081125 |
| Statins and blood pressure. | Archives of internal medicine 20081124 |
| The influence of statin medications on prostate-specific antigen levels. | Journal of the National Cancer Institute 20081105 |
| Statin suppresses apoptosis in osteoblastic cells: role of transforming growth factor-beta-Smad3 pathway. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081101 |
| Improved survival of diabetic foot ulcer patients 1995-2008: possible impact of aggressive cardiovascular risk management. | Diabetes care 20081101 |
| Impact of adherence to statins on chronic heart failure in primary prevention. | British journal of clinical pharmacology 20081101 |
| An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA's spontaneous adverse event reporting system. | Pharmacoepidemiology and drug safety 20081101 |
| CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction. | European heart journal 20081101 |
| Cloning of the dog bile salt export pump (BSEP; ABCB11) and functional comparison with the human and rat proteins. | Biopharmaceutics & drug disposition 20081101 |
| Rosuvastatin, pravastatin, and atorvastatin for the treatment of hypercholesterolaemia in HIV-infected patients receiving protease inhibitors. | Current HIV research 20081101 |
| [67-year-old patient with speech disorder and dysphagia]. | Deutsche medizinische Wochenschrift (1946) 20081101 |
| The efficacy and safety of ezetimibe for treatment of dyslipidemia after heart transplantation. | Transplantation proceedings 20081101 |
| Transition of psoriasiform drug eruption to psoriasis de novo evidenced by histopathology. | The Journal of dermatology 20081101 |
| Pravastatin prevents aortic atherosclerosis via modulation of signal transduction and activation of transcription 3 (STAT3) to attenuate interleukin-6 (IL-6) action in ApoE knockout mice. | International journal of molecular sciences 20081101 |
| The role of novel biomarkers of cardiovascular disease in chronic kidney disease: focus on adiponectin and leptin. | Current cardiology reviews 20081101 |
| Decreased plasma and cardiac matrix metalloproteinase activities in patients with coronary artery disease and treated with pravastatin. | European journal of pharmacology 20081010 |
| Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
| Lovastatin, but not pravastatin, limits in vitro infection due to Coxiella burnetii. | The Journal of antimicrobial chemotherapy 20081001 |
| Potent inhibition of cicatricial contraction in proliferative vitreoretinal diseases by statins. | Diabetes 20081001 |
| Suppression of CYP2B induction by alendronate-mediated farnesyl diphosphate synthase inhibition in primary cultured rat hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20081001 |
| Prenatal exposure to HMG-CoA reductase inhibitors: effects on fetal and neonatal outcomes. | Reproductive toxicology (Elmsford, N.Y.) 20081001 |
| Effect of albumin on the biliary clearance of compounds in sandwich-cultured rat hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20081001 |
| Statins limit Rickettsia conorii infection in cells. | International journal of antimicrobial agents 20081001 |
| Ptosis, diplopia and statins: an association? | European journal of neurology 20081001 |
| The relationship between the effect of pravastatin and risk factors for coronary heart disease in Japanese patients with hypercholesterolemia. | Circulation journal : official journal of the Japanese Circulation Society 20081001 |
| Practical risk prediction tools for coronary heart disease in mild to moderate hypercholesterolemia in Japan: originated from the MEGA study data. | Circulation journal : official journal of the Japanese Circulation Society 20081001 |
| Polymorphism of the hepatic influx transporter organic anion transporting polypeptide 1B1 is associated with increased cholesterol synthesis rate. | Pharmacogenetics and genomics 20081001 |
| Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. | The Journal of clinical investigation 20081001 |
| Statins: under investigation for increasing bone mineral density and augmenting fracture healing. | Expert opinion on investigational drugs 20081001 |
| A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model. | Innate immunity 20081001 |
| A gift from nature: the birth of the statins. | Nature medicine 20081001 |
| Comparison of the effect of lipophilic and hydrophilic statins on serum adiponectin levels in patients with mild hypertension and dyslipidemia: Kinki Adiponectin Interventional (KAI) Study. | Clinical and experimental hypertension (New York, N.Y. : 1993) 20081001 |
| Atorvastatin therapy is associated with reduced levels of N-terminal prohormone brain natriuretic peptide and improved cardiac function in patients with heart failure. | Clinical cardiology 20081001 |
| Influence of pitavastatin on glucose tolerance in patients with type 2 diabetes mellitus. | Journal of atherosclerosis and thrombosis 20081001 |
| Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress. | Hypertension research : official journal of the Japanese Society of Hypertension 20081001 |
| Excess coronary artery disease risk in South Asian immigrants: can dysfunctional high-density lipoprotein explain increased risk? | Vascular health and risk management 20081001 |
| Update on the clinical utility of fenofibrate in mixed dyslipidemias: mechanisms of action and rational prescribing. | Vascular health and risk management 20081001 |
| Baseline low-density lipoprotein cholesterol is an important predictor of the benefit of intensive lipid-lowering therapy: a PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) analysis. | Journal of the American College of Cardiology 20080909 |
| Phytosterols dissolved in diacylglycerol oil reinforce the cholesterol-lowering effect of low-dose pravastatin treatment. | Nutrition, metabolism, and cardiovascular diseases : NMCD 20080901 |
| Impact on mortality following first acute myocardial infarction of distance between home and hospital: cohort study. | Heart (British Cardiac Society) 20080901 |
| Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER. | Atherosclerosis 20080901 |
| Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population. | Atherosclerosis 20080901 |
| Statin therapy increases carotid plaque echogenicity in hypercholesterolemic patients. | Ultrasound in medicine & biology 20080901 |
| Effects of atorvastatin and pravastatin on glucose tolerance, adipokine levels and inflammatory markers in hypercholesterolaemic patients. | Clinical and experimental pharmacology & physiology 20080901 |
| Determination of sodium cromoglycate in human plasma by liquid chromatography with tandem mass. | Biomedical chromatography : BMC 20080901 |
| Pravastatin improves renal ischemia-reperfusion injury by inhibiting the mevalonate pathway. | Kidney international 20080901 |
| Mesodermal fate decisions of a stem cell: the Wnt switch. | Cellular and molecular life sciences : CMLS 20080901 |
| Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. | International journal of cancer 20080901 |
| Utility of a novel Oatp1b2 knockout mouse model for evaluating the role of Oatp1b2 in the hepatic uptake of model compounds. | Drug metabolism and disposition: the biological fate of chemicals 20080901 |
| In vitro biliary clearance of angiotensin II receptor blockers and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in sandwich-cultured rat hepatocytes: comparison with in vivo biliary clearance. | The Journal of pharmacology and experimental therapeutics 20080901 |
| Identification of the specific sequence recognized by Penicillium citrinum MlcR, a GAL4-type transcriptional activator of ML-236B (compactin) biosynthetic genes. | Fungal genetics and biology : FG & B 20080901 |
| Progression of kidney disease in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin versus usual care: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). | American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901 |
| Investigating the potential neuroprotective effects of statins on DNA damage in mouse striatum. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080901 |
| Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression. | Pharmacogenetics and genomics 20080901 |
| Multiple effects of HMG-CoA reductase inhibitors (statins) besides their lipid-lowering function. | Kidney international 20080901 |
| Outcomes of patients with acute coronary syndrome and previous coronary artery bypass grafting (from the Pravastatin or Atorvastatin Evaluation and Infection Therapy [PROVE IT-TIMI 22] and the Aggrastat to Zocor [A to Z] trials). | The American journal of cardiology 20080901 |
| Statins for slowing kidney disease progression: an as yet unproven indication. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901 |
| Pharmacogenomic importance of pravastatin. | Pharmacogenomics 20080901 |
| Effect of simvastatin on steroid-induced osteonecrosis evidenced by the serum lipid level and hepatic cytochrome P4503A in a rabbit model. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20080901 |
| HIV infection in the elderly. | Clinical interventions in aging 20080901 |
| Can HMG Co-A reductase inhibitors ('statins') slow the progression of age-related macular degeneration? The age-related maculopathy statin study (ARMSS). | Clinical interventions in aging 20080901 |
| [Impact of statins on clopidogrel platelet inhibition in patients with acute coronary syndrome or stable angina]. | Zhonghua xin xue guan bing za zhi 20080901 |
| Effects of pravastatin on obesity, diabetes, and adiponectin in diet-induced obese mice. | Obesity (Silver Spring, Md.) 20080901 |
| Mevinolin, citrinin and pigments of adlay angkak fermented by Monascus sp. | International journal of food microbiology 20080815 |
| Increased adiponectin synthesis in the visceral adipose tissue in men with coronary artery disease treated with pravastatin: a role of the attenuation of oxidative stress. | Atherosclerosis 20080801 |
| Correlates of LDL-cholesterol goal attainment in patients under lipid lowering therapy. | Atherosclerosis 20080801 |
| Association between global leukocyte DNA methylation, renal function, carotid intima-media thickness and plasma homocysteine in patients with stage 2-4 chronic kidney disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080801 |
| Effect of APOE genotype on lipid levels in patients with coronary heart disease during a 3-week inpatient rehabilitation program. | Clinical pharmacology and therapeutics 20080801 |
| Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin. | Molecular pharmacology 20080801 |
| Colesevelam HCl improves glycemic control and reduces LDL cholesterol in patients with inadequately controlled type 2 diabetes on sulfonylurea-based therapy. | Diabetes care 20080801 |
| Role of the murine organic anion-transporting polypeptide 1b2 (Oatp1b2) in drug disposition and hepatotoxicity. | Molecular pharmacology 20080801 |
| Involvement of organic anion transporting polypeptides in the toxicity of hydrophilic pravastatin and lipophilic fluvastatin in rat skeletal myofibres. | British journal of pharmacology 20080801 |
| Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study. | Experimental gerontology 20080801 |
| Dose-dependent effect of rosuvastatin on VLDL-apolipoprotein C-III kinetics in the metabolic syndrome. | Diabetes care 20080801 |
| Effects of statins on high-density lipoproteins: a potential contribution to cardiovascular benefit. | Cardiovascular drugs and therapy 20080801 |
| Subclinical atherosclerosis: what it is, what it means and what we can do about it. | International journal of clinical practice 20080801 |
| Impact of a combined treatment of angiotensin II type 1 receptor blockade and 3-hydroxy-3-methyl-glutaryl-CoA-reductase inhibition on secretory phospholipase A2-type IIA and low density lipoprotein oxidation in patients with coronary artery disease. | European heart journal 20080801 |
| Differential mechanisms of angiotensin II and PDGF-BB on migration and proliferation of coronary artery smooth muscle cells. | Journal of molecular and cellular cardiology 20080801 |
| LDL-C reductions and goal attainment among naive statin users in the Netherlands: real life results. | Current medical research and opinion 20080801 |
| Hyperglycemia induces apoptosis of human pancreatic islet endothelial cells: effects of pravastatin on the Akt survival pathway. | The American journal of pathology 20080801 |
| Pravastatin-induced colitis. | European journal of gastroenterology & hepatology 20080801 |
| Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study. | Pharmacogenetics and genomics 20080801 |
| Pravastatin reduces the risk for cardiovascular disease in Japanese hypercholesterolemic patients with impaired fasting glucose or diabetes: diabetes subanalysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA) Study. | Atherosclerosis 20080801 |
| Lipophilicity and cardiovascular outcome in patients with CHF. | American heart journal 20080801 |
| Determination of RBC membrane and serum lipid composition in Trinidadian type II diabetics with and without nephropathy. | Vascular health and risk management 20080801 |
| The Relationship Between HIV Infection and Cardiovascular Disease. | Current cardiology reviews 20080801 |
| Pharmacological prevention of peri-, and post-procedural myocardial injury in percutaneous coronary intervention. | Current cardiology reviews 20080801 |
| Role of pharmacogenomics in drug discovery and development. | Indian journal of pharmacology 20080801 |
| Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of dolichols in plants. | The Journal of biological chemistry 20080725 |
| LC and LC-MS methods for the investigation of polypills for the treatment of cardiovascular diseases. Part 1. Separation of active components and classification of their interaction/degradation products. | Journal of pharmaceutical and biomedical analysis 20080715 |
| Magnesium cation effect on passive diffusion of statin molecules: molecular chromatography approach. | Journal of pharmaceutical and biomedical analysis 20080715 |
| Re: The association between statins and cancer incidence in a veterans population. | Journal of the National Cancer Institute 20080702 |
| Gender-specific regulation of pancreatic islet blood flow, insulin levels and glycaemia in spontaneously diabetic Goto-Kakizaki rats. | Clinical science (London, England : 1979) 20080701 |
| Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia. | European journal of clinical pharmacology 20080701 |
| Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation. | Glia 20080701 |
| Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20080701 |
| On-line extraction coupled with liquid chromatography tandem mass spectrometry for quantitation of pravastatin and its metabolite in human serum. | Biomedical chromatography : BMC 20080701 |
| Interactions between cell death induced by statins and 7-ketocholesterol in rabbit aorta smooth muscle cells. | British journal of pharmacology 20080701 |
| Pravastatin attenuates carboplatin-induced cardiotoxicity via inhibition of oxidative stress associated apoptosis. | Apoptosis : an international journal on programmed cell death 20080701 |
| The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK. | Water research 20080701 |
| Relationship between biomarkers of oxidized low-density lipoprotein, statin therapy, quantitative coronary angiography, and atheroma: volume observations from the REVERSAL (Reversal of Atherosclerosis with Aggressive Lipid Lowering) study. | Journal of the American College of Cardiology 20080701 |
| Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging. | Nature medicine 20080701 |
| Treatment of coronary spastic angina with a statin in addition to a calcium channel blocker: a pilot study. | Journal of cardiovascular pharmacology 20080701 |
| Rejuvenating premature aging. | Nature medicine 20080701 |
| Lipid management: considerations in acute coronary syndrome. | Current cardiology reports 20080701 |
| Pravastatin increases the expression of the tissue inhibitor of matrix metalloproteinase-1 and the oncogene Bax in human aortic abdominal aneurysms. | Canadian journal of physiology and pharmacology 20080701 |
| Cost-effectiveness analysis of rosuvastatin versus atorvastatin, simvastatin, and pravastatin from a Canadian health system perspective. | Clinical therapeutics 20080701 |
| Atorvastatin-induced changes in plasma coenzyme q10 and brain natriuretic peptide in patients with coronary artery disease. | International heart journal 20080701 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line. | Experimental cell research 20080610 |
| Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies. | Lancet (London, England) 20080607 |
| Neuroprotection by pravastatin in acute ischemic stroke in rats. | Brain research reviews 20080601 |
| Effect of genipin on the biliary excretion of cholephilic compounds in rats. | Hepatology research : the official journal of the Japan Society of Hepatology 20080601 |
| Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease. | Journal of neurochemistry 20080601 |
| Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1. | Diabetes 20080601 |
| Association of circulating leukocyte count with coronary atherosclerosis regression after pravastatin treatment. | Atherosclerosis 20080601 |
| Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation but not via PDGF-BB expression. | American journal of physiology. Heart and circulatory physiology 20080601 |
| The comparative effectiveness of rosuvastatin vs. other statins in patients with an increased risk of failure to reach NCEP ATP III goal. | International journal of clinical practice 20080601 |
| Statins (HMG-coenzyme A reductase inhibitors)-biomimetic membrane binding mechanism investigated by molecular chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080601 |
| Efficacy of lipid-lowering medications in patients treated with clozapine: a naturalistic study. | Journal of clinical psychopharmacology 20080601 |
| Atherogenic lipoprotein particle size and concentrations and the effect of pravastatin in children with familial hypercholesterolemia. | The Journal of pediatrics 20080601 |
| The relation between extent of coronary artery disease measured by quantitative coronary angiography and changes in lipid profile: insights from trials of atherosclerosis regression. | The Journal of invasive cardiology 20080601 |
| Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid. | The AAPS journal 20080601 |
| Mortality in COPD: inevitable or preventable? Insights from the cardiovascular arena. | COPD 20080601 |
| Pravastatin: an evidence-based statin? | Expert opinion on drug metabolism & toxicology 20080601 |
| Pravastatin immunomodulates IL-6 and C-reactive protein, but not IL-1 and TNF-alpha, in cardio-pulmonary bypass. | European cytokine network 20080601 |
| Atorvastatin and cardiovascular risk in the elderly--patient considerations. | Clinical interventions in aging 20080601 |
| New evidences for C-reactive protein (CRP) deposits in the arterial intima as a cardiovascular risk factor. | Clinical interventions in aging 20080601 |
| Epidemiology and economics of statin use. | Irish medical journal 20080601 |
| [Pleiotropic effects of statins]. | Revista medica de Chile 20080601 |
| Relative safety profiles of high dose statin regimens. | Vascular health and risk management 20080601 |
| Early vascular aging (EVA): consequences and prevention. | Vascular health and risk management 20080601 |
| The secretory phospholipase A2 group IIA: a missing link between inflammation, activated renin-angiotensin system, and atherogenesis? | Vascular health and risk management 20080601 |
| Cardiovascular co-morbidity in rheumatic diseases. | Vascular health and risk management 20080601 |
| Fixed combinations in the management of hypertension: patient perspectives and rationale for development and utility of the olmesartan-amlodipine combination. | Vascular health and risk management 20080601 |
| [Metabolic side effects of antiretroviral therapy]. | Nederlands tijdschrift voor geneeskunde 20080531 |
| Repression of BK virus infection of human renal proximal tubular epithelial cells by pravastatin. | Transplantation 20080515 |
| Estimation of treatment effect adjusting for treatment changes using the intensity score method: application to a large primary prevention study for coronary events (MEGA study). | Statistics in medicine 20080510 |
| Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. | American journal of human genetics 20080509 |
| (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1h-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid (BMS-644950): a rationally designed orally efficacious 3-hydroxy-3-methylglutaryl coenzyme-a reductase inhibitor with reduced myotoxicity potential. | Journal of medicinal chemistry 20080508 |
| Monitoring cholesterol levels: measurement error or true change? | Annals of internal medicine 20080506 |
| An automated method for the simultaneous determination of pravastatin, 3-hydroxy isomeric metabolite, pravalactone and fenofibric acid in human plasma by sensitive liquid chromatography combined with diode array and tandem mass spectrometry detection. | Journal of chromatography. A 20080502 |
| Effects of statins on adipose tissue inflammation: their inhibitory effect on MyD88-independent IRF3/IFN-beta pathway in macrophages. | Arteriosclerosis, thrombosis, and vascular biology 20080501 |
| Treatment with an apolipoprotein A-1 mimetic peptide in combination with pravastatin inhibits collagen-induced arthritis. | Clinical immunology (Orlando, Fla.) 20080501 |
| Effective management of hypertension with dihydropyridine calcium channel blocker-based combination therapy in patients at high cardiovascular risk. | International journal of clinical practice 20080501 |
| Atorvastatin monotherapy vs. combination therapy in the management of patients with combined hyperlipidemia. | European journal of internal medicine 20080501 |
| Drug-induced liver injury in 2007. | Current opinion in gastroenterology 20080501 |
| The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15. | Pharmacogenetics and genomics 20080501 |
| High-dose atorvastatin does not negatively influence clinical outcomes among clopidogrel treated acute coronary syndrome patients--a Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) analysis. | American heart journal 20080501 |
| Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes. | Journal of pharmacological sciences 20080501 |
| Communicating the results of clinical research to participants: attitudes, practices, and future directions. | PLoS medicine 20080501 |
| Pravastatin as a therapeutic agent for atypical antipsychotic-induced metabolic syndrome in patients with schizophrenia. | CNS spectrums 20080501 |
| HMG-CoA reductase inhibitors deplete circulating classical and non-classical monocytes following human heart transplantation. | Transplant immunology 20080501 |
| Pathogenesis and management of lipoatrophy. | Current HIV/AIDS reports 20080501 |
| Effectiveness of lipid-lowering therapy in HIV patients. | Current opinion in HIV and AIDS 20080501 |
| Cardiovascular disease in systemic lupus erythematosus: the role of traditional and lupus related risk factors. | Current cardiology reviews 20080501 |
| The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans. | Journal of the American College of Cardiology 20080429 |
| Statin induced myotoxicity: the lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080423 |
| Association between risk of myopathy and cholesterol-lowering effect: a comparison of all statins. | Life sciences 20080423 |
| Reduction in blood pressure with statins: results from the UCSD Statin Study, a randomized trial. | Archives of internal medicine 20080414 |
| Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9. | The Journal of biological chemistry 20080411 |
| Granulocytic sarcoma with massive scalp involvement. | American journal of hematology 20080401 |
| The effect of HMG-CoA reductase inhibitors on naturally occurring CD4+CD25+ T cells. | Atherosclerosis 20080401 |
| Early changes in arterial structure and function following statin initiation: quantification by magnetic resonance imaging. | Atherosclerosis 20080401 |
| Regulation of the PTEN promoter by statins and SREBP. | Human molecular genetics 20080401 |
| Intracellular cholesterol modifies the ERAD of glucocerebrosidase in Gaucher disease patients. | Molecular genetics and metabolism 20080401 |
| Early Improvements in insulin sensitivity and inflammatory markers are induced by pravastatin in nondiabetic subjects with hypercholesterolemia. | Clinica chimica acta; international journal of clinical chemistry 20080401 |
| 'Real-life' reduction in cholesterol with statins, 1993 to 2002. | British journal of clinical pharmacology 20080401 |
| Statin treatment in hypercholesterolemic pregnant mice reduces cardiovascular risk factors in their offspring. | Hypertension (Dallas, Tex. : 1979) 20080401 |
| The value of N-terminal fragment of brain natriuretic peptide and tissue inhibitor of metalloproteinase-1 levels as predictors of cardiovascular outcome in the LIPID study. | European heart journal 20080401 |
| Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study. | Brain : a journal of neurology 20080401 |
| Initiating statins in the elderly: the evolving challenge. | Current opinion in endocrinology, diabetes, and obesity 20080401 |
| Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study. | Pharmacogenetics and genomics 20080401 |
| Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells. | Liver international : official journal of the International Association for the Study of the Liver 20080401 |
| Lipid levels and low-density lipoprotein cholesterol goal attainment in diabetic patients: rosuvastatin compared with other statins in usual care. | Expert opinion on pharmacotherapy 20080401 |
| Rationale and design of a study to examine lower targets for low-density lipoprotein-cholesterol and blood pressure in coronary artery disease patients. | Circulation journal : official journal of the Japanese Circulation Society 20080401 |
| Primary prevention with pravastatin for 5 years continued to prevent coronary events in the next 10 years. | Evidence-based nursing 20080401 |
| Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. | The American journal of gastroenterology 20080401 |
| Statins in esophageal cancer cell lines: promising lead? | The American journal of gastroenterology 20080401 |
| [Use of statins in children]. | Anales de pediatria (Barcelona, Spain : 2003) 20080401 |
| Inflammatory markers in nondiabetic and diabetic rat retinas exposed to ischemia followed by reperfusion. | Retina (Philadelphia, Pa.) 20080401 |
| Effects of rosuvastatin and pitavastatin on ischemia-induced myocardial stunning in dogs. | Journal of pharmacological sciences 20080401 |
| Can cheap generic statins achieve national cholesterol lowering targets? | Journal of health services research & policy 20080401 |
| Adjunctive interventions in myocardial infarction: the role of statin therapy. | Current atherosclerosis reports 20080401 |
| Pharmacological topics of bone metabolism: antiresorptive microbial compounds that inhibit osteoclast differentiation, function, and survival. | Journal of pharmacological sciences 20080401 |
| Do statins prevent or promote cancer? | Current oncology (Toronto, Ont.) 20080401 |
| Combination therapy in cholesterol reduction: focus on ezetimibe and statins. | Vascular health and risk management 20080401 |
| Orlistat in the prevention of diabetes in the obese patient. | Vascular health and risk management 20080401 |
| Clinical efficacy and safety of statins in managing cardiovascular risk. | Vascular health and risk management 20080401 |
| Vascular risk factors, cognitive decline, and dementia. | Vascular health and risk management 20080401 |
| Preferred drug lists: potential impact on healthcare economics. | Vascular health and risk management 20080401 |
| Monascus purpureus Went rice in nephrotic hyperlipidemia. | Indian journal of nephrology 20080401 |
| A case of vasospastic angina showing resolution of coronary vasospasm in acetylcholine provocation test corresponding to regression of coronary atherosclerosis. | International journal of cardiology 20080328 |
| Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes. | FEBS letters 20080319 |
| Differences in antitumor effects of various statins on human pancreatic cancer. | International journal of cancer 20080315 |
| Tendinous disorders attributed to statins: a study on ninety-six spontaneous reports in the period 1990-2005 and review of the literature. | Arthritis and rheumatism 20080315 |
| Hydrophobic statins induce autophagy in cultured human rhabdomyosarcoma cells. | Biochemical and biophysical research communications 20080307 |
| Association between ADAMTS1 matrix metalloproteinase gene variation, coronary heart disease, and benefit of statin therapy. | Arteriosclerosis, thrombosis, and vascular biology 20080301 |
| Estimating the extent of reporting to FDA: a case study of statin-associated rhabdomyolysis. | Pharmacoepidemiology and drug safety 20080301 |
| The Food and Drug Administration and over-the-counter statins: an opportunity lost? | Journal of clinical hypertension (Greenwich, Conn.) 20080301 |
| Inhibition of macrophage phagocytotic activity by a receptor-targeted polymer vesicle-based drug delivery formulation of pravastatin. | Journal of cardiovascular pharmacology 20080301 |
| Flexible initial dosing of atorvastatin based upon initial low-density lipoprotein cholesterol levels in type 2 diabetic patients. | The Korean journal of internal medicine 20080301 |
| Statins impair antitumor effects of rituximab by inducing conformational changes of CD20. | PLoS medicine 20080301 |
| Metabolic myopathies discovered during investigations of statin myopathy. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20080301 |
| [Effects of pravastatin in prevention of diabetes and mechanism thereof: experiment with non-obese diabetic mice]. | Zhonghua yi xue za zhi 20080226 |
| Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE IT-TIMI 22 trial. | Journal of the American College of Cardiology 20080219 |
| Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-kappaB pathway. | Biochemical pharmacology 20080215 |
| Cardiovascular health in New Zealand: areas of concern and targets for improvement in 2008 and beyond. | The New Zealand medical journal 20080215 |
| Differences in cardiovascular mortality between Australia and New Zealand according to socioeconomic status: findings from the Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study. | The New Zealand medical journal 20080215 |
| Usefulness of C-reactive protein and interleukin-6 as predictors of outcomes in patients with chronic obstructive pulmonary disease receiving pravastatin. | The American journal of cardiology 20080215 |
| Determination of two HMG-CoA reductase inhibitors, pravastatin and pitavastatin, in plasma samples using liquid chromatography-tandem mass spectrometry for pharmaceutical study. | Biomedical chromatography : BMC 20080201 |
| The Guinea pig as a preclinical model for demonstrating the efficacy and safety of statins. | The Journal of pharmacology and experimental therapeutics 20080201 |
| Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C. | Molecular genetics and genomics : MGG 20080201 |
| Phospholipid chlorohydrin induces leukocyte adhesion to ApoE-/- mouse arteries via upregulation of P-selectin. | Free radical biology & medicine 20080201 |
| Chronic kidney disease mineral and bone disorder in children. | Pediatric nephrology (Berlin, Germany) 20080201 |
| Use of recommended medications after myocardial infarction in Austria. | European journal of epidemiology 20080201 |
| Hepatoselectivity of statins: design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors. | Bioorganic & medicinal chemistry letters 20080201 |
| Effect of statin dose on incidence of atrial fibrillation: data from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) and Aggrastat to Zocor (A to Z) trials. | American heart journal 20080201 |
| Class effects of statins in elderly patients with congestive heart failure: a population-based analysis. | American heart journal 20080201 |
| Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. | European journal of clinical pharmacology 20080201 |
| Direct effect of statins on homocysteine-induced endothelial adhesiveness: potential impact to human atherosclerosis. | European journal of clinical investigation 20080201 |
| Statins induce lethal effects in acute myeloblastic leukemia [corrected] cells within 72 hours. | Leukemia & lymphoma 20080201 |
| Usefulness of statin pretreatment to prevent contrast-induced nephropathy and to improve long-term outcome in patients undergoing percutaneous coronary intervention. | The American journal of cardiology 20080201 |
| Impact of systemic hypertension on the cardiovascular benefits of statin therapy--a meta-analysis. | The American journal of cardiology 20080201 |
| The mechanism of carrier-mediated transport of folates in BeWo cells: the involvement of heme carrier protein 1 in placental folate transport. | Bioscience, biotechnology, and biochemistry 20080201 |
| What is the evidence in favor of low-dose statin therapy in 2008? | Current atherosclerosis reports 20080201 |
| Update on the use of fibrates: focus on bezafibrate. | Vascular health and risk management 20080201 |
| Perioperative use of statins in noncardiac surgery. | Vascular health and risk management 20080201 |
| High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease. | Vascular health and risk management 20080201 |
| Usefulness of pravastatin in primary prevention of cardiovascular events in women: analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA study). | Circulation 20080129 |
| Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials. | Journal of the American College of Cardiology 20080129 |
| Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study. | Journal of the American College of Cardiology 20080129 |
| The association between statins and cancer incidence in a veterans population. | Journal of the National Cancer Institute 20080116 |
| Synergistic induction of apoptosis by HMG-CoA reductase inhibitor and histone deacetylases inhibitor in HeLa cells. | Biochemical and biophysical research communications 20080111 |
| Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia. | Journal of medicinal chemistry 20080110 |
| Long-term follow-up of the West of Scotland Coronary Prevention Study. | The New England journal of medicine 20080110 |
| Long-term follow-up of the West of Scotland Coronary Prevention Study. | The New England journal of medicine 20080110 |
| Long-term follow-up of the West of Scotland Coronary Prevention Study. | The New England journal of medicine 20080110 |
| [Influence of pravastatin on blood lipids and serum high sensitive C-reactive protein in patients undergoing conventional coronary artery bypass grafting under on-pump: a clinical study of 81 cases]. | Zhonghua yi xue za zhi 20080108 |
| Hydroxymethylglutaryl--CoA reductase inhibitor inhibits induction of nitric oxide synthase in 3T3--L1 preadipocytes. | Life sciences 20080102 |
| Long-term effects of pravastatin and fosinopril on peripheral endothelial function in albuminuric subjects. | Atherosclerosis 20080101 |
| Effect of pravastatin on the development of diabetes and adiponectin production. | Atherosclerosis 20080101 |
| Estimation of the marginal survival time in the presence of dependent competing risks using inverse probability of censoring weighted (IPCW) methods. | Pharmaceutical statistics 20080101 |
| Hydrophobic but not hydrophilic statins enhance phagocytosis and decrease apoptosis of human peripheral blood cells in vitro. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101 |
| The significance of compliance and persistence in the treatment of diabetes, hypertension and dyslipidaemia: a review. | International journal of clinical practice 20080101 |
| Myeloid-related protein 8/14 and the risk of cardiovascular death or myocardial infarction after an acute coronary syndrome in the Pravastatin or Atorvastatin Evaluation and Infection Therapy: Thrombolysis in Myocardial Infarction (PROVE IT-TIMI 22) trial. | American heart journal 20080101 |
| Protection of pancreatic beta-cells: is it feasible? | Nutrition, metabolism, and cardiovascular diseases : NMCD 20080101 |
| Effect of early use of low-dose pravastatin on major adverse cardiac events in patients with acute myocardial infarction: the OACIS-LIPID Study. | Circulation journal : official journal of the Japanese Circulation Society 20080101 |
| Effects of beta-hydroxy-beta-methylbutyrate (HMB) on exercise performance and body composition across varying levels of age, sex, and training experience: A review. | Nutrition & metabolism 20080101 |
| Statins for secondary prevention in elderly patients: a hierarchical bayesian meta-analysis. | Journal of the American College of Cardiology 20080101 |
| Contribution of multidrug resistance-associated protein 2 to secretory intestinal transport of organic anions. | Biological & pharmaceutical bulletin 20080101 |
| [Effect of electro-acupuncture at Fenglong (GV 16) on nitric oxide and endothelin in rats with hyperlipidemia]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080101 |
| Lowering LDL-C for optimal protection in high-risk patients. | The American journal of managed care 20080101 |
| The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. | BMC cancer 20080101 |
| Pravastatin attenuates left ventricular remodeling and diastolic dysfunction in angiotensin II-induced hypertensive mice. | Journal of cardiovascular pharmacology 20080101 |
| Impact of cytochrome P450 3A4-metabolized statins on the antiplatelet effect of a 600-mg loading dose clopidogrel and on clinical outcome in patients undergoing elective coronary stent placement. | Thrombosis and haemostasis 20080101 |
| Incidence of adverse events with HMG-CoA reductase inhibitors in liver transplant patients. | Clinical transplantation 20080101 |
| Inflammation, carotid intima-media thickness and atherosclerosis in rheumatoid arthritis. | Arthritis research & therapy 20080101 |
| Recombinant gas vesicles from Halobacterium sp. displaying SIV peptides demonstrate biotechnology potential as a pathogen peptide delivery vehicle. | BMC biotechnology 20080101 |
| [Effects of electroacupuncture at 'Fenglong' (ST 40) on NO, ET and CGRP levels in the rat with hyperlipidemia]. | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20080101 |
| Should We Use PPAR Agonists to Reduce Cardiovascular Risk? | PPAR research 20080101 |
| When research seems like clinical care: a qualitative study of the communication of individual cancer genetic research results. | BMC medical ethics 20080101 |
| The effects of a graduated aerobic exercise programme on cardiovascular disease risk factors in the NHS workplace: a randomised controlled trial. | Journal of occupational medicine and toxicology (London, England) 20080101 |
| Primary prevention with pravastatin for 5 years continued to prevent coronary events in the following 10 years. | ACP journal club 20080101 |
| [Classification of Streptomyces strain Z314 and purification of its product pravastatin]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20080101 |
| Does productivity influence priority setting? A case study from the field of CVD prevention. | Cost effectiveness and resource allocation : C/E 20080101 |
| Patient-centered modular secondary prevention following acute coronary syndrome: a randomized controlled trial. | Journal of cardiopulmonary rehabilitation and prevention 20080101 |
| The efficacy of pharmacotherapy for decreasing the expansion rate of abdominal aortic aneurysms: a systematic review and meta-analysis. | PloS one 20080101 |
| The Lipid lowering and Onset of Renal Disease (LORD) Trial: a randomized double blind placebo controlled trial assessing the effect of atorvastatin on the progression of kidney disease. | BMC nephrology 20080101 |
| The functional consequences of genetic variations in transporter genes encoding human organic anion-transporting polypeptide family members. | Expert opinion on drug metabolism & toxicology 20080101 |
| Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT. | AIDS research and therapy 20080101 |
| Chinese red yeast rice (Monascus purpureus-fermented rice) promotes bone formation. | Chinese medicine 20080101 |
| Cost-effectiveness of rosuvastatin in the prevention of ischemic heart disease in Portugal. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101 |
| PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease. | PPAR research 20080101 |
| Statin use is associated with fewer periodontal lesions: A retrospective study. | BMC oral health 20080101 |
| Ezetimibe effectively lowers LDL-cholesterol in cardiac allograft recipients on stable statin therapy. | Clinical transplantation 20080101 |
| Implementing electronic clinical reminders for lipid management in patients with ischemic heart disease in the veterans health administration: QUERI Series. | Implementation science : IS 20080101 |
| Fixed-dose combination therapy with statins: strengths, limitations, and clinical and regulatory considerations. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101 |
| Lipid-altering therapy and atrial fibrillation. | Cardiology in review 20080101 |
| Pharmacokinetic comparison of the potential over-the-counter statins simvastatin, lovastatin, fluvastatin and pravastatin. | Clinical pharmacokinetics 20080101 |
| Statin induced myopathy and myalgia: time trend analysis and comparison of risk associated with statin class from 1991-2006. | PloS one 20080101 |
| Diagnostic uncertainty of Takotusbo cardiomyopathy in a woman with cardiovascular risk factors hijacked at gunpoint: a case report. | Cases journal 20080101 |
| [Rosuvastatin for the treatment of dyslipidemia in HIV-infected patients receiving highly active antiretroviral therapy. Preliminary experience]. | Enfermedades infecciosas y microbiologia clinica 20080101 |
| Trends in total cholesterol screening and in prescribing lipid-lowering drugs in general practice in the period 1994-2003. | BMC family practice 20080101 |
| Multicenter double blind trial of autologous bone marrow mononuclear cell transplantation through intracoronary injection post acute myocardium infarction - MiHeart/AMI study. | Trials 20080101 |
| The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies. | PloS one 20080101 |
| Statin potentiates human platelet eNOS activity without enhancing eNOS mRNA and protein levels. | Cerebrovascular diseases (Basel, Switzerland) 20080101 |
| Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism. | Journal of human genetics 20080101 |
| Secondary prevention of coronary heart disease in elderly patients following myocardial infarction: are all HMG-CoA reductase inhibitors alike? | Drugs & aging 20080101 |
| Modelling neurofibromatosis type 1 tibial dysplasia and its treatment with lovastatin. | BMC medicine 20080101 |
| Clinical drugs that interact with St. John's wort and implication in drug development. | Current pharmaceutical design 20080101 |
| [Interrelation between the pathways of isoprenoid biosynthesis and carbon source catabolism in anaerobic and facultatively anaerobic bacteria]. | Mikrobiologiia 20080101 |
| Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study. | PloS one 20080101 |
| Treatment of altered body composition in HIV-associated lipodystrophy: comparison of rosiglitazone, pravastatin, and recombinant human growth hormone. | HIV clinical trials 20080101 |
| Risk factors for cerebral microbleeds in the elderly. | Cerebrovascular diseases (Basel, Switzerland) 20080101 |
| Chemoembolization combined with pravastatin improves survival in patients with hepatocellular carcinoma. | Digestion 20080101 |
| Pilot study of an interactive voice response system to improve medication refill compliance. | BMC medical informatics and decision making 20080101 |
| Dyslipidemia in primary care--prevalence, recognition, treatment and control: data from the German Metabolic and Cardiovascular Risk Project (GEMCAS). | Cardiovascular diabetology 20080101 |
| Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules. | Lipids in health and disease 20080101 |
| The prince and the pauper. A tale of anticancer targeted agents. | Molecular cancer 20080101 |
| Low HDL cholesterol, smoking and IL-13 R130Q polymorphism are associated with myocardial infarction in Greek Cypriot males. A pilot study. | The open cardiovascular medicine journal 20080101 |
| In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites. | BMC bioinformatics 20080101 |
| Net efficacy adjusted for risk (NEAR): a simple procedure for measuring risk:benefit balance. | PloS one 20080101 |
| Efficacy of statins in familial hypercholesterolaemia: a long term cohort study. | BMJ (Clinical research ed.) 20080101 |
| Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids. | Nutrition and cancer 20080101 |
| Hypoalbuminaemia--a marker of cardiovascular disease in patients with chronic kidney disease stages II-IV. | International journal of medical sciences 20080101 |
| Practical management of dyslipidemia with elevated lipoprotein(a). | Journal of the American Pharmacists Association : JAPhA 20080101 |
| High speed clinical data retrieval system with event time sequence feature: with 10 years of clinical data of Hamamatsu University Hospital CPOE. | Methods of information in medicine 20080101 |
| Parametric conditional frailty models for recurrent cardiovascular events in the lipid study. | Clinical trials (London, England) 20080101 |
| [Effects of pravastatin on myocardial connexin 43, IFN-gamma and IL-10 expressions in a murine model of viral myocarditis induced by Coxsackievirus B3]. | Zhonghua xin xue guan bing za zhi 20080101 |
| Clinical review: Critical care management of spontaneous intracerebral hemorrhage. | Critical care (London, England) 20080101 |
| Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death. | Thrombosis journal 20080101 |
| Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse. | BMC developmental biology 20080101 |
| Statins Activate Human PPARalpha Promoter and Increase PPARalpha mRNA Expression and Activation in HepG2 Cells. | PPAR research 20080101 |
| Statin treatment, carotid atherosclerotic plaque macrophage infiltration and circulating inflammatory markers. | The open cardiovascular medicine journal 20080101 |
| Determination of key intermediates in cholesterol and bile acid biosynthesis by stable isotope dilution mass spectrometry. | Analytical chemistry insights 20080101 |
| Effect of onion and beet on plasma and liver lipids, platelet aggregation, and erythrocyte Na efflux in simvastatin treated hypercholesterolmic rats. | Nutrition research and practice 20080101 |
| Pharmacogenomics Bias - Systematic distortion of study results by genetic heterogeneity. | GMS health technology assessment 20080101 |
| Microbial production and biomedical applications of lovastatin. | Indian journal of pharmaceutical sciences 20080101 |
| Stability Indicating RP-HPLC Estimation of Atorvastatin Calcium and Amlodipine Besylate in Pharmaceutical Formulations. | Indian journal of pharmaceutical sciences 20080101 |
| Hypolipidemia: a word of caution. | The Libyan journal of medicine 20080101 |
| Frequency and predictors of tablet splitting in statin prescriptions: a population-based analysis. | Open medicine : a peer-reviewed, independent, open-access journal 20080101 |
| Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome. | Clinical and experimental gastroenterology 20080101 |
| Macrophage NADPH oxidase activation, impaired cholesterol fluxes, and increased cholesterol biosynthesis in diabetic mice: a stimulatory role for D-glucose. | Atherosclerosis 20071201 |
| Rab-small GTPases are involved in fluvastatin and pravastatin-induced vacuolation in rat skeletal myofibers. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071201 |
| Mechanisms of progression of chronic kidney disease. | Pediatric nephrology (Berlin, Germany) 20071201 |
| The effects of high dose pravastatin and low dose pravastatin and ezetimibe combination therapy on lipid, glucose metabolism and inflammation. | Inflammation 20071201 |
| Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells. | Lipids 20071201 |
| Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways. | Plant cell reports 20071201 |
| Effect of pravastatin on sympathetic reinnervation in postinfarcted rats. | American journal of physiology. Heart and circulatory physiology 20071201 |
| Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake. | American journal of physiology. Heart and circulatory physiology 20071201 |
| The new acyl-CoA cholesterol acyltransferase inhibitor SMP-797 does not interact with statins via OATP1B1 in human cryopreserved hepatocytes and oocytes expressing systems. | Biopharmaceutics & drug disposition 20071201 |
| P-glycoprotein is downregulated in KG1a-primitive leukemia cells by LDL cholesterol deprivation and by HMG-CoA reductase inhibitors. | Experimental hematology 20071201 |
| Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter. | Pharmaceutical research 20071201 |
| Effects of initiation and acute withdrawal of statins on the neurovascular coupling mechanism in healthy, normocholesterolemic humans. | Stroke 20071201 |
| Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice. | Journal of hypertension 20071201 |
| Patient complexity: more than comorbidity. the vector model of complexity. | Journal of general internal medicine 20071201 |
| Importance of intensive lipid lowering in acute coronary syndrome and percutaneous coronary intervention. | Journal of interventional cardiology 20071201 |
| Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling. | Journal of pharmacological sciences 20071201 |
| A comparison of the effectiveness of lipid-lowering therapy between HIV- and non-HIV-infected subjects with hyperlipidaemia. | International journal of STD & AIDS 20071201 |
| Biological effects of acute pravastatin treatment in patients after aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled trial. | Journal of neurosurgery 20071201 |
| The antitumour activities of statins. | Current oncology (Toronto, Ont.) 20071201 |
| Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma. | Molecular cancer therapeutics 20071201 |
| Evaluation of proton pump inhibitor use in patients with acute coronary syndromes based on risk factors for gastrointestinal bleed. | Critical pathways in cardiology 20071201 |
| Production of secondary metabolites by some terverticillate penicillia on carbohydrate-rich and meat substrates. | Journal of food protection 20071201 |
| Understanding practice patterns and low-density lipoprotein cholesterol goal attainment implications of switching patients from simvastatin in a health plan setting. | The American journal of managed care 20071201 |
| Down-regulation of intestinal multidrug resistance-associated protein 2 in long-evans cinnamon rats. | Drug metabolism and pharmacokinetics 20071201 |
| A review of nateglinide in the management of patients with type 2 diabetes. | Vascular health and risk management 20071201 |
| Endothelial dysfunction in diabetes mellitus. | Vascular health and risk management 20071201 |
| Rationale for multiple risk intervention: the need to move from theory to practice. | Vascular health and risk management 20071201 |
| Secular trends in lipid-lowering treatment and lipid levels after a first acute myocardial infarction. | Vascular health and risk management 20071201 |
| Short-term effect of the HMG-CoA reductase inhibitor rosuvastatin on erythrocyte nitric oxide synthase activity. | Vascular health and risk management 20071201 |
| Treatment of non-alcoholic fatty liver disease. | Therapeutics and clinical risk management 20071201 |
| Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions. | Current neuropharmacology 20071201 |
| Postischemic administration of HMG CoA reductase inhibitor inhibits infarct expansion after transient middle cerebral artery occlusion. | Brain research 20071121 |
| Effect of withdrawal of pravastatin therapy on C-reactive protein and low-density lipoprotein cholesterol. | The American journal of cardiology 20071115 |
| Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial. | Hepatology (Baltimore, Md.) 20071101 |
| Society already achieves economic benefits from generic substitution but fails to do the same for therapeutic substitution. | British journal of clinical pharmacology 20071101 |
| Decreased plasma soluble RAGE in patients with hypercholesterolemia: effects of statins. | Free radical biology & medicine 20071101 |
| Is there life after plaque rupture? | Biochemical Society transactions 20071101 |
| Bilateral pleural effusions associated with pravastatin sodium treatment. | The European respiratory journal 20071101 |
| Association between apolipoprotein E4 and cognitive decline in elderly adults. | Journal of the American Geriatrics Society 20071101 |
| A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in vivo. | Calcified tissue international 20071101 |
| Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro. | Molecular cancer therapeutics 20071101 |
| Comparative evaluation of the effects of statins on human stem and cancer cells in vitro. | Reproductive biomedicine online 20071101 |
| Titration patterns with rosuvastatin as compared with other statins in clinical practice: a retrospective observational cohort study using an electronic medical record database. | Clinical therapeutics 20071101 |
| Long-term follow-up of the West of Scotland Coronary Prevention Study. | The New England journal of medicine 20071011 |
| Primary prevention of coronary artery disease. | The New England journal of medicine 20071011 |
| Pravastatin improved glucose metabolism associated with increasing plasma adiponectin in patients with impaired glucose tolerance and coronary artery disease. | Atherosclerosis 20071001 |
| Anti-inflammatory effects of pravastatin on Helicobacter pylori-induced gastritis in mice. | Digestive diseases and sciences 20071001 |
| Risk of congenital anomalies in pregnant users of statin drugs. | British journal of clinical pharmacology 20071001 |
| Salicylic acid-induced taxol production and isopentenyl pyrophosphate biosynthesis in suspension cultures of Taxus chinensis var. mairei. | Cell biology international 20071001 |
| Growth hormone (GH) replacement decreases serum total and LDL-cholesterol in hypopituitary patients on maintenance HMG CoA reductase inhibitor (statin) therapy. | Clinical endocrinology 20071001 |
| P-glycoprotein has differential effects on the disposition of statin acid and lactone forms in mdr1a/b knockout and wild-type mice. | Drug metabolism and disposition: the biological fate of chemicals 20071001 |
| From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing. | Cellular and molecular life sciences : CMLS 20071001 |
| Effectiveness of statins in Medicare-eligible patients and patients < 65 years using clinical practice data. | International journal of clinical practice 20071001 |
| Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials). | The American journal of cardiology 20071001 |
| Impact of C-reactive protein on treatment of patients with cardiovascular disease. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20071001 |
| Pravastatin reduces myocardial infarct size via increasing protein kinase C-dependent nitric oxide, decreasing oxyradicals and opening the mitochondrial adenosine triphosphate-sensitive potassium channels in rabbits. | Circulation journal : official journal of the Japanese Circulation Society 20071001 |
| Life style-related diseases of the digestive system: cell culture system for the screening of anti-hepatitis C virus (HCV) reagents: suppression of HCV replication by statins and synergistic action with interferon. | Journal of pharmacological sciences 20071001 |
| A meta-analysis to evaluate the efficacy of statins in children with familial hypercholesterolemia. | International journal of clinical pharmacology and therapeutics 20071001 |
| Inhibition of balloon injury-induced neointimal formation by olmesartan and pravastatin in rats with insulin resistance. | Hypertension research : official journal of the Japanese Society of Hypertension 20071001 |
| Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion. | Journal of cardiovascular pharmacology 20071001 |
| The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation. | Vascular health and risk management 20071001 |
| Are pleiotropic effects of statins real? | Vascular health and risk management 20071001 |
| Cholesterol lowering for secondary prevention: what statin dose should we use? | Vascular health and risk management 20071001 |
| Nebivolol in the treatment of chronic heart failure. | Vascular health and risk management 20071001 |
| Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? The single pill of amlodipine/atorvastatin. | Vascular health and risk management 20071001 |
| Colesevelam hydrochloride: reducing atherosclerotic coronary heart disease risk factors. | Vascular health and risk management 20071001 |
| Primary prevention of cardiovascular disease with pravastatin. | Current atherosclerosis reports 20071001 |
| Progress update: Pharmacological treatment of Alzheimer's disease. | Neuropsychiatric disease and treatment 20071001 |
| Effective uptake of N-acetylglucosamine-conjugated liposomes by cardiomyocytes in vitro. | Journal of controlled release : official journal of the Controlled Release Society 20070926 |
| Meta-analysis of the role of statin therapy in reducing myocardial infarction following elective percutaneous coronary intervention. | The American journal of cardiology 20070915 |
| Pravastatin Inhibits the Rho/CCN2/extracellular matrix cascade in human fibrosis explants and improves radiation-induced intestinal fibrosis in rats. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070915 |
| Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells. | European journal of pharmacology 20070910 |
| In vivo coronary plaque histology in patients with stable and acute coronary syndromes: relationships with hyperlipidemic status and statin treatment. | Atherosclerosis 20070901 |
| A pravastatin dose-escalation study in systemic lupus erythematosus. | Rheumatology international 20070901 |
| SLCO1B1 521T-->C functional genetic polymorphism and lipid-lowering efficacy of multiple-dose pravastatin in Chinese coronary heart disease patients. | British journal of clinical pharmacology 20070901 |
| Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling. | The Journal of pharmacology and experimental therapeutics 20070901 |
| Involvement of rat and human organic anion transporter 3 in the renal tubular secretion of topotecan [(S)-9-dimethylaminomethyl-10-hydroxy-camptothecin hydrochloride]. | The Journal of pharmacology and experimental therapeutics 20070901 |
| Genetic analysis of fluvastatin response and dyslipidemia in renal transplant recipients. | Journal of lipid research 20070901 |
| The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin. | The Journal of pharmacology and experimental therapeutics 20070901 |
| Physiogenomic association of statin-related myalgia to serotonin receptors. | Muscle & nerve 20070901 |
| Flow cytometric evaluation of synergistic pro-apoptotic effects of statins and clofibrates in IM-9 human lymphoblasts. | Clinical and experimental pharmacology & physiology 20070901 |
| Effectiveness of rosuvastatin in low-density lipoprotein cholesterol lowering and National Cholesterol Education Program Adult Treatment Panel guideline III LDL-C goal attainment compared to other statins among diabetes mellitus patients: a retrospective study using an electronic medical records dataset in the United States. | Current medical research and opinion 20070901 |
| Usefulness of hydrophilic vs lipophilic statins after acute myocardial infarction: subanalysis of MUSASHI-AMI. | Circulation journal : official journal of the Japanese Circulation Society 20070901 |
| Simvastatin enhances induction of inducible nitric oxide synthase in 3T3-L1 adipocytes. | Free radical research 20070901 |
| Ezetimibe in heart transplantation: initial experience. | Transplantation proceedings 20070901 |
| Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: effects of gender, CYP46, and ApoE polymorphisms. | Journal of molecular neuroscience : MN 20070901 |
| Low-density lipoprotein cholesterol (LDL-C) levels and LDL-C goal attainment among elderly patients treated with rosuvastatin compared with other statins in routine clinical practice. | The American journal of geriatric pharmacotherapy 20070901 |
| [The antiplatelet effect of clopidogrel is not attenuated by statin treatment in patients with acute coronary syndromes undergone coronary stenting]. | Zhonghua xin xue guan bing za zhi 20070901 |
| Retraction: Zheng Z, Chen B. Effects of Pravastatin on neuroprotection and neurogenesis after cerebral ischemia in rats. Neuroscience Bulletin 2007,23(4):189-197. | Neuroscience bulletin 20070901 |
| Use of lipid-modulating drugs in complicated course of coronary heart disease. | Bulletin of experimental biology and medicine 20070901 |
| Strategies for eliminating PrP(c) as substrate for prion conversion and for enhancing PrP(Sc) degradation. | Veterinary microbiology 20070831 |
| Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease. | Neurology 20070828 |
| Formation of amyloids by Abeta-(1-42) on NGF-differentiated PC12 cells: roles of gangliosides and cholesterol. | Journal of molecular biology 20070824 |
| The application of microbore UPLC/oa-TOF-MS and 1H NMR spectroscopy to the metabonomic analysis of rat urine following the intravenous administration of pravastatin. | Journal of pharmaceutical and biomedical analysis 20070815 |
| Statin treatment in children with familial hypercholesterolemia: the younger, the better. | Circulation 20070807 |
| Stimulation programs for pediatric drug research--do children really benefit? | European journal of pediatrics 20070801 |
| Chemotherapy and zoledronate sensitize solid tumour cells to Vgamma9Vdelta2 T cell cytotoxicity. | Cancer immunology, immunotherapy : CII 20070801 |
| Statins in elderly patients with acute coronary syndrome: an analysis of dose and class effects in typical practice. | Heart (British Cardiac Society) 20070801 |
| Effect of reduced levels of the LDL receptor of Ehrlich ascites tumor cells on cholesterol uptake and cell proliferation: a coculture study with baby hamster kidney cells. | Cell biology international 20070801 |
| Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid. | Drug metabolism and disposition: the biological fate of chemicals 20070801 |
| Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3. | Drug metabolism and disposition: the biological fate of chemicals 20070801 |
| Apolipoprotein E polymorphisms influence effect of pravastatin on survival after myocardial infarction in a Mediterranean population: the GISSI-Prevenzione study. | European heart journal 20070801 |
| Cholesterol lowering with statins: how WOSCOPS confounded the skeptics. | Atherosclerosis. Supplements 20070801 |
| Primary prevention of cardiovascular diseases among hypercholesterolemic Japanese with a low dose of pravastatin. | Atherosclerosis. Supplements 20070801 |
| A trilogy of primary prevention statin trials. Panel discussion. | Atherosclerosis. Supplements 20070801 |
| Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants. | Pharmacogenetics and genomics 20070801 |
| Low HDL-C predicts the onset of transplant vasculopathy in pediatric cardiac recipients on pravastatin therapy. | Pediatric transplantation 20070801 |
| On the factors modulating the effect of statins on malignant cell proliferation. | Cancer investigation 20070801 |
| Successful mitigation of delayed intestinal radiation injury using pravastatin is not associated with acute injury improvement or tumor protection. | International journal of radiation oncology, biology, physics 20070801 |
| Impact of statin dosing intensity on transaminase and creatine kinase. | The American journal of medicine 20070801 |
| [Case report of cholesterol crystal embolism 1 month after carotid stenting]. | No shinkei geka. Neurological surgery 20070801 |
| Strategies in the treatment of HIV-1-associated adipose redistribution syndromes. | Expert opinion on pharmacotherapy 20070801 |
| PROactive 07: pioglitazone in the treatment of type 2 diabetes: results of the PROactive study. | Vascular health and risk management 20070801 |
| Review of tipranavir in the treatment of drug-resistant HIV. | Therapeutics and clinical risk management 20070801 |
| [Effects of pravastatin on the expression of endothelin induced by aldosterone in rat cardiac fibroblasts]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070801 |
| Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials. | Journal of the American College of Cardiology 20070731 |
| Lack of evidence of a clopidogrel-statin interaction in the CHARISMA trial. | Journal of the American College of Cardiology 20070724 |
| Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status. | The Journal of biological chemistry 20070720 |
| Effect of statin withdrawal on frequency of cardiac events after vascular surgery. | The American journal of cardiology 20070715 |
| A new compound-specific pleiotropic effect of statins: modification of plasma gamma-tocopherol levels. | Atherosclerosis 20070701 |
| RhoA-dependent PAI-1 gene expression induced in endothelial cells by monocyte adhesion mediates geranylgeranyl transferase I and Ca2+ signaling. | Atherosclerosis 20070701 |
| SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma. | Journal of lipid research 20070701 |
| Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation. | Stem cells (Dayton, Ohio) 20070701 |
| Rac1, RhoA, and Cdc42 participate in HeLa cell invasion by group B streptococcus. | FEMS microbiology letters 20070701 |
| Statins and cancer. | Epidemiology (Cambridge, Mass.) 20070701 |
| Effects of Pravastatin on neuroprotection and neurogenesis after cerebral ischemia in rats. | Neuroscience bulletin 20070701 |
| [The primary observation on the effect of pravastatin to non-ischemic heart failure]. | Zhonghua xin xue guan bing za zhi 20070701 |
| Treatment strategies for HIV lipodystrophy. | Current opinion in HIV and AIDS 20070701 |
| Chromatography-mass spectrometry methods for the quantitation of statins in biological samples. | Journal of pharmaceutical and biomedical analysis 20070628 |
| Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study. | Archives of internal medicine 20070625 |
| Long-term prognostic value of neopterin: a novel marker of monocyte activation in patients with acute coronary syndrome. | Circulation 20070619 |
| Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity. | Journal of cellular biochemistry 20070601 |
| Modulation of COX-2 expression by statins in human monocytic cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070601 |
| Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition. | American journal of respiratory cell and molecular biology 20070601 |
| Use of hepatocytes to assess the contribution of hepatic uptake to clearance in vivo. | Drug metabolism and disposition: the biological fate of chemicals 20070601 |
| Effect of pravastatin treatment on Chlamydia pneumoniae infection, inflammation and serum lipids in NIH/S mice. | International journal of antimicrobial agents 20070601 |
| Preferable effect of pravastatin compared to atorvastatin on beta cell function in Japanese early-state type 2 diabetes with hypercholesterolemia. | Endocrine journal 20070601 |
| Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction. | Clinical immunology (Orlando, Fla.) 20070601 |
| Effect of pravastatin on markers of endothelial activation in dialysis patients. | Nephrology (Carlton, Vic.) 20070601 |
| Difference in early effects of statin therapy on coronary and forearm flow reserve in postmenopausal hypercholesterolemic women. | Circulation journal : official journal of the Japanese Circulation Society 20070601 |
| The effects of statin and fibrate on lowering small dense LDL- cholesterol in hyperlipidemic patients with type 2 diabetes. | Journal of atherosclerosis and thrombosis 20070601 |
| Multivariate risk assessment and risk score cards in hypertension. | Vascular health and risk management 20070601 |
| Reducing the risks of cardiovascular disease in liver allograft recipients. | Transplantation 20070515 |
| Effects of pravastatin in murine collagen-induced arthritis. | Rheumatology international 20070501 |
| Synergistic effects of pravastatin and pioglitazone in renal tubular epithelial cells induced by transforming growth factor-beta1. | Cell biology international 20070501 |
| The influence of macrolide antibiotics on the uptake of organic anions and drugs mediated by OATP1B1 and OATP1B3. | Drug metabolism and disposition: the biological fate of chemicals 20070501 |
| Amiodarone interacts with simvastatin but not with pravastatin disposition kinetics. | Clinical pharmacology and therapeutics 20070501 |
| Effects of acute pravastatin treatment on intensity of rescue therapy, length of inpatient stay, and 6-month outcome in patients after aneurysmal subarachnoid hemorrhage. | Stroke 20070501 |
| Drug-induced liver disease in 2006. | Current opinion in gastroenterology 20070501 |
| Effect of HMGCoA reductase inhibitors on cytochrome P450 expression in endothelial cell line. | Journal of cardiovascular pharmacology 20070501 |
| Gemfibrozil and its glucuronide inhibit the hepatic uptake of pravastatin mediated by OATP1B1. | Xenobiotica; the fate of foreign compounds in biological systems 20070501 |
| Which statin, what dose? | Drug and therapeutics bulletin 20070501 |
| Indian medicinal mushrooms as a source of antioxidant and antitumor agents. | Journal of clinical biochemistry and nutrition 20070501 |
| Protective effects of coenzyme q(10) on decreased oxidative stress resistance induced by simvastatin. | Journal of clinical biochemistry and nutrition 20070501 |
| Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study. | Blood 20070401 |
| Amelioration of steroids and cyclosporine-resistant nephrotic syndrome by pravastatin. | Pediatric nephrology (Berlin, Germany) 20070401 |
| Comparison of the antiatherosclerotic effects of dihydropyridine calcium channel blocker and HMG-CoA reductase inhibitor on hypercholesterolemic rabbits. | Vascular pharmacology 20070401 |
| Tissue factor and nitric oxide: a controversial relationship! | Journal of thrombosis and thrombolysis 20070401 |
| Decline in total cerebral blood flow is linked with increase in periventricular but not deep white matter hyperintensities. | Radiology 20070401 |
| Pravastatin decreases wall shear stress and blood velocity in the internal carotid artery without affecting flow volume: results from the PROSPER MRI study. | Stroke 20070401 |
| The effect of aggressive versus conventional lipid-lowering therapy on markers of inflammatory and oxidative stress. | Cardiovascular drugs and therapy 20070401 |
| Nitropravastatin stimulates reparative neovascularisation and improves recovery from limb Ischaemia in type-1 diabetic mice. | British journal of pharmacology 20070401 |
| Acquired ichthyosis with pravastatin. | Journal of the European Academy of Dermatology and Venereology : JEADV 20070401 |
| A systematic review and economic evaluation of statins for the prevention of coronary events. | Health technology assessment (Winchester, England) 20070401 |
| Inhibition of human organic anion transporter 3 mediated pravastatin transport by gemfibrozil and the metabolites in humans. | Xenobiotica; the fate of foreign compounds in biological systems 20070401 |
| Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study. | Annals of the New York Academy of Sciences 20070401 |
| Characterization of Salmonella enterica serovar Typhimurium DT104 invasion in an epithelial cell line (IPEC J2) from porcine small intestine. | Veterinary microbiology 20070310 |
| Effects of pravastatin on ventricular remodeling by activation of myocardial KATP channels in infarcted rats: role of 70-kDa S6 kinase. | Basic research in cardiology 20070301 |
| Cholesterol-dependent balance between evoked and spontaneous synaptic vesicle recycling. | The Journal of physiology 20070301 |
| Pravastatin enhances beneficial effects of olmesartan on vascular injury of salt-sensitive hypertensive rats, via pleiotropic effects. | Arteriosclerosis, thrombosis, and vascular biology 20070301 |
| Predicting the oxidative metabolism of statins: an application of the MetaSite algorithm. | Pharmaceutical research 20070301 |
| Statins and renal function. Is the compound and dose making a difference? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070301 |
| Pravastatin inhibits arrhythmias induced by coronary artery ischemia in anesthetized rats. | Journal of pharmacological sciences 20070301 |
| Impact of gender on statin efficacy. | Current medical research and opinion 20070301 |
| Two-week treatment with pravastatin improves ventriculo-vascular haemodynamic interactions in young men with type 1 diabetes. | Diabetes & vascular disease research 20070301 |
| Neuropsychiatric consequences of cardiovascular medications. | Dialogues in clinical neuroscience 20070301 |
| C-reactive protein and prediction of coronary heart disease and global vascular events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). | Circulation 20070227 |
| Pravastatin and cancer: an unproven association. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070227 |
| Does pravastatin promote cancer in elderly patients? A meta-analysis. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070227 |
| Effects of intensive versus moderate lipid-lowering therapy on myocardial ischemia in older patients with coronary heart disease: results of the Study Assessing Goals in the Elderly (SAGE). | Circulation 20070213 |
| Statin therapy and the elderly: SAGE advice? | Circulation 20070213 |
| Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cells. | European journal of pharmacology 20070205 |
| Systematic review and meta-analysis of clinically relevant adverse events from HMG CoA reductase inhibitor trials worldwide from 1982 to present. | Pharmacoepidemiology and drug safety 20070201 |
| Development and validation of a preclinical food effect model. | Journal of pharmaceutical sciences 20070201 |
| Effect of colestimide therapy for glycemic control in type 2 diabetes mellitus with hypercholesterolemia. | Endocrine journal 20070201 |
| Lipid raft-dependent endocytosis of metallothionein in HepG2 cells. | Journal of cellular physiology 20070201 |
| Severe citrate toxicity complicating volunteer apheresis platelet donation. | Journal of clinical apheresis 20070201 |
| Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor. | Analytical and bioanalytical chemistry 20070201 |
| [Medical treatment in peripheral arterial disease: a professional practice study in 262 patients]. | La Revue de medecine interne 20070201 |
| Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans. | Pharmaceutical research 20070201 |
| Lipophilic statins suppress cytotoxicity by freshly isolated natural killer cells through modulation of granule exocytosis. | International immunology 20070201 |
| Effect of atorvastatin and pravastatin on platelet inhibition by aspirin and clopidogrel treatment in patients with coronary stent thrombosis. | The American journal of cardiology 20070201 |
| Safety of lovastatin/extended release niacin compared with lovastatin alone, atorvastatin alone, pravastatin alone, and simvastatin alone (from the United States Food and Drug Administration adverse event reporting system). | The American journal of cardiology 20070201 |
| Estimating the impact of adding C-reactive protein as a criterion for lipid lowering treatment in the United States. | Journal of general internal medicine 20070201 |
| [Perspectives in the treatment of subarachnoid-hemorrhage-induced cerebral vasospasm]. | Neurocirugia (Asturias, Spain) 20070201 |
| Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy. | Clinical therapeutics 20070201 |
| Effect of lipid-lowering and anti-hypertensive drugs on plasma homocysteine levels. | Vascular health and risk management 20070201 |
| [The comparison in vitro the effects of pravastatin and quercetin on the selected structural parameters of membrane erythrocytes from patients with hypercholesterolemia]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070201 |
| Can telomere length predict cardiovascular risk? | Lancet (London, England) 20070113 |
| Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. | Lancet (London, England) 20070113 |
| The effect of statin on the aortic gene expression profiling. | International journal of cardiology 20070102 |
| Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity. | Journal of hepatology 20070101 |
| Enhanced cardiac production of matrix metalloproteinase-2 and -9 and its attenuation associated with pravastatin treatment in patients with acute myocardial infarction. | Clinical science (London, England : 1979) 20070101 |
| Pravastatin reverses the down-regulating effect of inflammation on beta-adrenergic receptors: a disease-drug interaction between inflammation, pravastatin, and propranolol. | Vascular pharmacology 20070101 |
| The nitric oxide-donating pravastatin derivative, NCX 6550 [(1S-[1alpha(betaS*, deltaS*), 2alpha, 6alpha, 8beta-(R*), 8a alpha]]-1,2,6,7,8,8a-Hexahydro-beta, delta, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic acid 4-(nitrooxy)butyl ester)], reduces splenocyte adhesion and reactive oxygen species generation in normal and atherosclerotic mice. | The Journal of pharmacology and experimental therapeutics 20070101 |
| Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2. | American journal of physiology. Gastrointestinal and liver physiology 20070101 |
| Vasoactive drugs enhance pancreatic islet blood flow, augment insulin secretion and improve glucose tolerance in female rats. | Clinical science (London, England : 1979) 20070101 |
| The value of the electrocardiogram in risk assessment in primary prevention: experience from the West of Scotland Coronary Prevention Study. | Journal of electrocardiology 20070101 |
| From pathophysiology to targeted therapy for atherothrombosis: a role for the combination of statin and aspirin in secondary prevention. | Pharmacology & therapeutics 20070101 |
| A rapid and specific approach for direct measurement of pravastatin concentration in plasma by LC-MS/MS employing solid-phase extraction. | Biomedical chromatography : BMC 20070101 |
| Impact of high dose statin trials on hospital prescribers. | European journal of clinical pharmacology 20070101 |
| Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study. | American heart journal 20070101 |
| Differential impact of atorvastatin vs pravastatin on progressive insulin resistance and left ventricular diastolic dysfunction in a rat model of type II diabetes. | Circulation journal : official journal of the Japanese Circulation Society 20070101 |
| Optimal low-density lipoprotein cholesterol lowering--morning versus evening statin administration. | The Annals of pharmacotherapy 20070101 |
| Probable statin-induced testicular pain. | The Annals of pharmacotherapy 20070101 |
| Immunization of LDL receptor-deficient mice with beta2-glycoprotein 1 or human serum albumin induces a more inflammatory phenotype in atherosclerotic plaques. | Thrombosis and haemostasis 20070101 |
| Update on heart disease. Evidence mounts for even lower LDL. | Diabetes self-management 20070101 |
| Drug-related hepatotoxicity in a renal transplant recipient with long-term survival and hepatitis C. | Annals of hepatology 20070101 |
| [Effect of hypolipidemic treatment on the composition of bile and the risk or cholesterol gallstone disease]. | Casopis lekaru ceskych 20070101 |
| Pravastatin inhibits carboxymethyllysine-induced monocyte chemoattractant protein 1 expression in podocytes via prevention of signalling events. | Nephron. Experimental nephrology 20070101 |
| Effects of statins on restenosis after coronary stent implantation. | Angiology 20070101 |
| Safety of rosuvastatin: update on 16,876 rosuvastatin-treated patients in a multinational clinical trial program. | Cardiology 20070101 |
| Evidence for placebo effects on physical but not on biochemical outcome parameters: a review of clinical trials. | BMC medicine 20070101 |
| The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | Immunity & ageing : I & A 20070101 |
| Asymptomatic statin-induced rhabdomyolysis after long-term therapy with the hydrophilic drug pravastatin. | Clinical therapeutics 20070101 |
| How equitable are GP practice prescribing rates for statins?: an ecological study in four primary care trusts in North West England. | International journal for equity in health 20070101 |
| The gender specific frequency of risk factor and CHD diagnoses prior to incident MI: a community study. | BMC family practice 20070101 |
| Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol. | Lipids in health and disease 20070101 |
| Pravastatin in HIV-infected patients treated with protease inhibitors: a placebo-controlled randomized study. | HIV clinical trials 20070101 |
| Can clopidogrel monotherapy influence vascular remodeling? | Vascular and endovascular surgery 20070101 |
| Understanding the effects of a decentralized budget on physicians' compliance with guidelines for statin prescription--a multilevel methodological approach. | BMC health services research 20070101 |
| Generic drug policy in Australia: a community pharmacy perspective. | Australia and New Zealand health policy 20070101 |
| Statin's cost-effectiveness: a Canadian analysis of commonly prescribed generic and brand name statins. | The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20070101 |
| Essential and non-essential DNA replication genes in the model halophilic Archaeon, Halobacterium sp. NRC-1. | BMC genetics 20070101 |
| Ezetimibe is effective when added to maximally tolerated lipid lowering therapy in patients with HIV. | Lipids in health and disease 20070101 |
| Coronary reactivity, homocysteine and methylenetetrahydrofolate reductase gene variation in young men during pravastatin therapy. | Vascular pharmacology 20070101 |
| [Rhabdomyolysis probably caused by interaction between efalizumab and pravastatin]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20070101 |
| Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin, amiodarone, and atazanavir. | Journal of the American Board of Family Medicine : JABFM 20070101 |
| Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease. | BMC medicine 20070101 |
| Mevastatin increases eNO synthase expression and inhibits lipid peroxidation in human endothelial cells. | Clinical hemorheology and microcirculation 20070101 |
| HMG-CoA reductase inhibitors reduce nicotine-induced expression of cellular adhesion molecules in cultured human coronary endothelial cells. | Journal of vascular research 20070101 |
| Does pravastatin therapy affect cardiac enzyme levels after percutaneous coronary intervention? | Advances in therapy 20070101 |
| Analysis of factors associated with statin adherence in a hierarchical model considering physician, pharmacy, patient, and prescription characteristics. | Journal of managed care pharmacy : JMCP 20070101 |
| Clinical review: Prevention and therapy of vasospasm in subarachnoid hemorrhage. | Critical care (London, England) 20070101 |
| Can drug treatment prevent disease in common practice? | Zeitschrift fur arztliche Fortbildung und Qualitatssicherung 20070101 |
| Effect of medium pH on the cytotoxicity of hydrophilic statins. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101 |
| The PreCardio-study protocol--a randomized clinical trial of a multidisciplinary electronic cardiovascular prevention programme. | BMC cardiovascular disorders 20070101 |
| Estimation of treatment effect adjusting for dependent censoring using the IPCW method: an application to a large primary prevention study for coronary events (MEGA study). | Clinical trials (London, England) 20070101 |
| Improvement of myocardial blood flow by lipid-lowering therapy with pravastatin is modulated by apolipoprotein E genotype. | Scandinavian journal of clinical and laboratory investigation 20070101 |
| Locally applied Simvastatin improves fracture healing in mice. | BMC musculoskeletal disorders 20070101 |
| A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. | BMC medical genetics 20070101 |
| Effects of atorvastatin on the different phases of atherogenesis. | Drugs 20070101 |
| Atorvastatin efficacy in the primary and secondary prevention of cardiovascular events. | Drugs 20070101 |
| Atorvastatin efficacy in the prevention of cardiovascular events in patients with diabetes mellitus and/or metabolic syndrome. | Drugs 20070101 |
| Atorvastatin: its clinical role in cerebrovascular prevention. | Drugs 20070101 |
| Are HIV positive patients resistant to statin therapy? | Lipids in health and disease 20070101 |
| Fish-oil esters of plant sterols differ from vegetable-oil sterol esters in triglycerides lowering, carotenoid bioavailability and impact on plasminogen activator inhibitor-1 (PAI-1) concentrations in hypercholesterolemic subjects. | Lipids in health and disease 20070101 |
| Medicinal importance of grapefruit juice and its interaction with various drugs. | Nutrition journal 20070101 |
| Effects of long-term pravastatin treatment on serum and urinary monocyte chemoattractant protein-1 levels and renal function in type 2 diabetic patients with normoalbuminuria. | Renal failure 20070101 |
| Analysis of Schistosoma mansoni genes shared with Deuterostomia and with possible roles in host interactions. | BMC genomics 20070101 |
| Effect of pravastatin on phenotypical transformation of fibroblasts and hypertrophy of cardiomyocytes in culture. | Bulletin of experimental biology and medicine 20070101 |
| Effect of PlA1/A2 glycoprotein IIIa gene polymorphism on the long-term outcome after successful coronary stenting. | Thrombosis journal 20070101 |
| The Ontario printed educational message (OPEM) trial to narrow the evidence-practice gap with respect to prescribing practices of general and family physicians: a cluster randomized controlled trial, targeting the care of individuals with diabetes and hypertension in Ontario, Canada. | Implementation science : IS 20070101 |
| Atorvastatin: a pharmacoeconomic review of its use in the primary and secondary prevention of cardiovascular events. | PharmacoEconomics 20070101 |
| Aspects of statin prescribing in Norwegian counties with high, average and low statin consumption - an individual-level prescription database study. | BMC clinical pharmacology 20070101 |
| The effects of atorvastatin therapy on endothelial function in patients with coronary artery disease. | Cardiovascular ultrasound 20070101 |
| A critical gap between recommended and achieved LDL-cholesterol levels. Results of statin therapy in Slovakia. | Bratislavske lekarske listy 20070101 |
| [Hypercholesterolemia in men and women of various age. Part II. The problem of efficacy and safety of statins]. | Kardiologiia 20070101 |
| [Long-term follow-up of the West of Scotland Coronary Prevention Study]. | Kardiologiia 20070101 |
| Statins in hepatobiliary diseases: effects, indications and risks. | Acta gastro-enterologica Belgica 20070101 |
| Statin-Induced Increase in HDL-C and Renal Function in Coronary Heart Disease Patients. | The open cardiovascular medicine journal 20070101 |
| Atherosclerosis, cholesterol, nutrition, and statins--a critical review. | German medical science : GMS e-journal 20070101 |
| [Pravastatin and acetylsalycilic acid fixed-combination: a strategy to improve cardiovascular outcomes]. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101 |
| Effect of Coenzyme Q10 and green tea on plasma and liver lipids, platelet aggregation, TBARS production and erythrocyte Na leak in simvastatin treated hypercholesterolmic rats. | Nutrition research and practice 20070101 |
| Targeting receptors, transporters and site of absorption to improve oral drug delivery. | Drug target insights 20070101 |
| Crystalline polymorphism and molecular structure of sodium pravastatin. | The journal of physical chemistry. B 20061228 |
| Cholesterol depletion reduces serotonin binding and signaling via human 5-HT(7(a)) receptors. | European journal of pharmacology 20061215 |
| The MEGA study. | Lancet (London, England) 20061209 |
| The MEGA study. | Lancet (London, England) 20061209 |
| Beyond lipid lowering: What have we learned about the benefits of statins from the acute coronary syndromes trials? | The American journal of cardiology 20061204 |
| Molecular basis of differences among statins and a comparison with antioxidant vitamins. | The American journal of cardiology 20061204 |
| Effect of pravastatin on left ventricular mass in the two-kidney, one-clip hypertensive rats. | American journal of physiology. Heart and circulatory physiology 20061201 |
| Effect of levothyroxine on total lipid profiles as assessed by analytical capillary isotachophoresis in a patient with hypothyroidism. | Endocrine journal 20061201 |
| Asp92Asn polymorphism in the myeloid IgA Fc receptor is associated with myocardial infarction in two disparate populations: CARE and WOSCOPS. | Arteriosclerosis, thrombosis, and vascular biology 20061201 |
| The safety and efficacy of achieving very low LDL-cholesterol concentrations with high dose statin therapy. | Current opinion in lipidology 20061201 |
| The protective effect of HMG-CoA reductase inhibitors against monocrotaline-induced pulmonary hypertension in the rat might not be a class effect: comparison of pravastatin and atorvastatin. | Naunyn-Schmiedeberg's archives of pharmacology 20061201 |
| [Multiple mononeuropathy associated to treatment with pravastatin]. | Revista de neurologia 20061201 |
| Nicotinic acid: new/old drug. Immediate or sustained release: too risky for a drug with no proven benefit. | Prescrire international 20061201 |
| Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. | Clinical pharmacology and therapeutics 20061201 |
| Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid. | Journal of Alzheimer's disease : JAD 20061201 |
| Preservation of the blood brain barrier integrity may underlie neuroprotective effects of statins in Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20061201 |
| Influence of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on ubiquinone levels in rat skeletal muscle and heart: relationship to cytotoxicity and inhibitory activity for cholesterol synthesis in human skeletal muscle cells. | Journal of atherosclerosis and thrombosis 20061201 |
| Distinct effects of pravastatin, atorvastatin, and simvastatin on insulin secretion from a beta-cell line, MIN6 cells. | Journal of atherosclerosis and thrombosis 20061201 |
| Effects of direct-to-consumer advertising of hydroxymethylglutaryl coenzyme a reductase inhibitors on attainment of LDL-C goals. | Clinical therapeutics 20061201 |
| Olmesartan medoxomil: current status of its use in monotherapy. | Vascular health and risk management 20061201 |
| Who should receive a statin drug to lower cardiovascular risk? Does the drug and the dose of the drug matter? | Vascular health and risk management 20061201 |
| HIV-associated lipodystrophy syndrome. | Collegium antropologicum 20061201 |
| Management of hyperlipidemia with statins in the older patient. | Clinical interventions in aging 20061201 |
| Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy. | AIDS (London, England) 20061128 |
| Pravastatin: a potential cause for acute pancreatitis. | World journal of gastroenterology 20061121 |
| Ezetimibe, a promising lipid-lowering agent for the treatment of dyslipidaemia in HIV-infected patients with poor response to statins. | AIDS (London, England) 20061114 |
| Multitherapy for diabetes. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20061107 |
| Paradoxical increase in lumen size during progression of coronary atherosclerosis: observations from the REVERSAL trial. | Atherosclerosis 20061101 |
| The effect of statins on urinary albumin excretion and glomerular filtration rate: results from both a randomized clinical trial and an observational cohort study. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061101 |
| Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics. | Pharmacogenetics and genomics 20061101 |
| The effect of statins on preservation of kidney function in patients with coronary artery disease. | Current opinion in cardiology 20061101 |
| Role of P-glycoprotein in statin drug interactions. | Pharmacotherapy 20061101 |
| Statins, fibrates, and melanoma risk: a systematic review and meta-analysis. | Journal of the National Cancer Institute 20061101 |
| Statins induce mammalian target of rapamycin (mTOR)-mediated inhibition of Akt signaling and sensitize p53-deficient cells to cytostatic drugs. | Molecular cancer therapeutics 20061101 |
| Spillover effects of restrictive drug formularies in the statin class: a descriptive study of the Medicaid preferred drug list in Texas. | Managed care interface 20061101 |
| Expanding options with a wider range of rosuvastatin doses. | Clinical therapeutics 20061101 |
| [J-STARS (Japan statin treatment against recurrent stroke)]. | Nihon rinsho. Japanese journal of clinical medicine 20061028 |
| Are statins analogues of vitamin D? | Lancet (London, England) 20061007 |
| Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions. | Pharmacology & therapeutics 20061001 |
| Angiotensin II-mediated oxidative stress and procollagen-1 expression in cardiac fibroblasts: blockade by pravastatin and pioglitazone. | American journal of physiology. Heart and circulatory physiology 20061001 |
| Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity. | Cardiovascular research 20061001 |
| Statins and cerebral vasomotor reactivity: implications for a new therapy? | Stroke 20061001 |
| Calcification and cellularity in human aortic heart valve tissue determine the differentiation of bone-marrow-derived cells. | Journal of molecular and cellular cardiology 20061001 |
| Acute coronary syndromes and diabetes: Is intensive lipid lowering beneficial? Results of the PROVE IT-TIMI 22 trial. | European heart journal 20061001 |
| Mevastatin inhibits proliferation of rat ovarian theca-interstitial cells by blocking the mitogen-activated protein kinase pathway. | Fertility and sterility 20061001 |
| Toxicity of statins on rat skeletal muscle mitochondria. | Cellular and molecular life sciences : CMLS 20061001 |
| SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin. | Clinical pharmacology and therapeutics 20061001 |
| Not all age-related white matter hyperintensities are the same: a magnetization transfer imaging study. | AJNR. American journal of neuroradiology 20061001 |
| Rising to the challenge of treating high-risk patients. | The American journal of managed care 20061001 |
| A therapeutic dose of the lipophilic statin pitavastatin enhances oxidant-induced apoptosis in human vascular smooth muscle cells. | Journal of cardiovascular pharmacology 20061001 |
| Japan: are statins still good for everybody? | Lancet (London, England) 20060930 |
| Primary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomised controlled trial. | Lancet (London, England) 20060930 |
| MUBs, a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation. | The Journal of biological chemistry 20060915 |
| Effects of acute treatment with statins on cerebral autoregulation in patients after aneurysmal subarachnoid hemorrhage. | Neurosurgical focus 20060915 |
| Additive effects of combined blockade of AT1 receptor and HMG-CoA reductase on left ventricular remodeling in infarcted rats. | American journal of physiology. Heart and circulatory physiology 20060901 |
| Statin therapy induces ultrastructural damage in skeletal muscle in patients without myalgia. | The Journal of pathology 20060901 |
| Pravastatin prolongs graft survival in an allogeneic rat model of orthotopic single lung transplantation. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060901 |
| The key role of apoptosis in the pathogenesis and treatment of pulmonary hypertension. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060901 |
| The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS. | Naunyn-Schmiedeberg's archives of pharmacology 20060901 |
| Protective effects of pravastatin in murine lipopolysaccharide-induced acute lung injury. | Clinical and experimental pharmacology & physiology 20060901 |
| Pravastatin prevents ischemia-reperfusion injury in rat sciatic nerve. | Surgical neurology 20060901 |
| Pravastatin decreases blood pressure in hypertensive and hypercholesterolemic patients receiving antihypertensive treatment. | Circulation journal : official journal of the Japanese Circulation Society 20060901 |
| Fluvastatin treatment is not associated with an increased incidence of cancer. | International journal of clinical practice 20060901 |
| Pravastatin use and the five-year incidence of cancer in coronary heart disease patients: from the prevention of coronary sclerosis study. | Journal of epidemiology 20060901 |
| Serum lipoprotein(a) dynamics before/after menopause and long-term effects of hormone replacement therapy on lipoprotein(a) levels in middle-aged and older Japanese women. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060901 |
| Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells. | Molecular cancer therapeutics 20060901 |
| Pravastatin in vivo reduces mononuclear cell migration through endothelial monolayers. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060901 |
| Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease. | Vascular health and risk management 20060901 |
| A review of omega-3 ethyl esters for cardiovascular prevention and treatment of increased blood triglyceride levels. | Vascular health and risk management 20060901 |
| Vascular dementia: prevention and treatment. | Clinical interventions in aging 20060901 |
| Pleiotropic effects of statins and early benefit in the PROVE IT-TIMI-22 study. | Journal of the American College of Cardiology 20060815 |
| Pitavastatin-induced downregulation of CCR2 and CCR5 in monocytes is associated with the arrest of cell-cycle in S phase. | Atherosclerosis 20060801 |
| Effect of pravastatin on blood pressure in people with cardiovascular disease. | Journal of human hypertension 20060801 |
| 25-Hydroxycholesterol has a dual effect on the proliferation of cultured rat astrocytes. | Neuropharmacology 20060801 |
| Hypothesis: the antitumor activities of statins may be mediated by IL-18. | Journal of leukocyte biology 20060801 |
| Cholesterol, C-reactive protein, and cerebrovascular events following intensive and moderate statin therapy. | Journal of thrombosis and thrombolysis 20060801 |
| Association of statin therapy and increased survival in patients with multiple organ dysfunction syndrome. | Intensive care medicine 20060801 |
| Screening of compactin-resistant microorganisms capable of converting compactin to pravastatin. | Current microbiology 20060801 |
| Statin treatment is not associated with consistent alterations in inflammatory status of carotid atherosclerotic plaques: a retrospective study in 378 patients undergoing carotid endarterectomy. | Stroke 20060801 |
| Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction. | Current opinion in lipidology 20060801 |
| Potential clinical utility of high-density lipoprotein-mimetic peptides. | Current opinion in lipidology 20060801 |
| Protective effect of pravastatin on vascular endothelium in patients with systemic sclerosis: a pilot study. | Annals of the rheumatic diseases 20060801 |
| Insulin generates free radicals in human fibroblasts ex vivo by a protein kinase C-dependent mechanism, which is inhibited by pravastatin. | Free radical biology & medicine 20060801 |
| Clopidogrel-statin interaction: a mountain or a mole hill? | American heart journal 20060801 |
| The 4G/5G PAI-1 polymorphism influences the endothelial response to IL-1 and the modulatory effect of pravastatin. | Journal of thrombosis and haemostasis : JTH 20060801 |
| Plasma cholesteryl ester transfer protein concentrations predict cardiovascular events in patients with coronary artery disease treated with pravastatin. | Journal of internal medicine 20060801 |
| The effects of HMG-CoA reductase inhibitor on vascular progenitor cells. | Journal of pharmacological sciences 20060801 |
| Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion. | PLoS biology 20060801 |
| Statins, fracture risk, and bone remodeling: What is true? | The American journal of the medical sciences 20060801 |
| Pravastatin prevents myocardium from ischemia-induced fibrosis by protecting vascular endothelial cells exposed to oxidative stress. | Cardiovascular drugs and therapy 20060801 |
| Statins in the treatment of chronic heart failure: a systematic review. | PLoS medicine 20060801 |
| Statins, especially atorvastatin, may improve survival following brachytherapy for clinically localized prostate cancer. | Urologic nursing 20060801 |
| Both hepatitis C virus and Chlamydia pneumoniae infection are related to the progression of carotid atherosclerosis in patients undergoing lipid lowering therapy. | Fukuoka igaku zasshi = Hukuoka acta medica 20060801 |
| The role of the central melanocortin system in the regulation of food intake and energy homeostasis: lessons from mouse models. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20060729 |
| Pancreatic islet blood flow is selectively enhanced by captopril, irbesartan and pravastatin, and suppressed by palmitate. | Biochemical and biophysical research communications 20060721 |
| The year in non-ST-segment elevation acute coronary syndromes. | Journal of the American College of Cardiology 20060718 |
| Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolites. | The EMBO journal 20060712 |
| Endothelial Protection, AT1 blockade and Cholesterol-Dependent Oxidative Stress: the EPAS trial. | Circulation 20060704 |
| Neither plasma coenzyme Q10 concentration, nor its decline during pravastatin therapy, is linked to recurrent cardiovascular disease events: a prospective case-control study from the LIPID study. | Atherosclerosis 20060701 |
| Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma. | International journal of cancer 20060701 |
| Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans. | Drug metabolism and disposition: the biological fate of chemicals 20060701 |
| Cyclodextrins but not compactin inhibit the lateral diffusion of membrane proteins independent of cholesterol. | Traffic (Copenhagen, Denmark) 20060701 |
| Different anti-HCV profiles of statins and their potential for combination therapy with interferon. | Hepatology (Baltimore, Md.) 20060701 |
| Management of cardiovascular risk in patients receiving calcineurin inhibitors--a case report. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Persistence and adherence to cholesterol lowering agents: evidence from Régie de l'Assurance Maladie du Québec data. | American heart journal 20060701 |
| Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion. | The European journal of neuroscience 20060701 |
| Statin but not non-statin lipid-lowering drugs decrease fracture risk: a nation-wide case-control study. | Calcified tissue international 20060701 |
| Combination therapy with ezetimibe and simvastatin to achieve aggressive LDL reduction. | Expert review of cardiovascular therapy 20060701 |
| The effect of 6 months of treatment with pravastatin on serum adiponection concentrations in Japanese patients with coronary artery disease and hypercholesterolemia: a pilot study. | Clinical therapeutics 20060701 |
| Determinants of arterial wall remodeling during lipid-lowering therapy: serial intravascular ultrasound observations from the Reversal of Atherosclerosis with Aggressive Lipid Lowering Therapy (REVERSAL) trial. | Circulation 20060620 |
| Incadronate inhibits aminopeptidase N expression in prostatic PC-3 cells. | Cancer letters 20060618 |
| Proteinuria, impaired kidney function, and adverse outcomes in people with coronary disease: analysis of a previously conducted randomised trial. | BMJ (Clinical research ed.) 20060617 |
| [High lowering of lipids can melt coronary plaques -- is coronary disease reversible?]. | MMW Fortschritte der Medizin 20060615 |
| [For coronary disease patients is certain: the lower the LDL the better]. | MMW Fortschritte der Medizin 20060615 |
| Intensive statin therapy and the risk of hospitalization for heart failure after an acute coronary syndrome in the PROVE IT-TIMI 22 study. | Journal of the American College of Cardiology 20060606 |
| N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination. | The Journal of nutritional biochemistry 20060601 |
| ApoE plasma levels and risk of cardiovascular mortality in old age. | PLoS medicine 20060601 |
| Does random treatment assignment cause harm to research participants? | PLoS medicine 20060601 |
| Pharmacokinetics and response to pravastatin in paediatric patients with familial hypercholesterolaemia and in paediatric cardiac transplant recipients in relation to polymorphisms of the SLCO1B1 and ABCB1 genes. | British journal of clinical pharmacology 20060601 |
| Effects of obesity on lipid-lowering, anti-inflammatory, and antiatherosclerotic benefits of atorvastatin or pravastatin in patients with coronary artery disease (from the REVERSAL Study). | The American journal of cardiology 20060601 |
| Pravastatin improves remodeling and cardiac function after myocardial infarction by an antiinflammatory mechanism rather than by the induction of angiogenesis. | The Annals of thoracic surgery 20060601 |
| Invited commentary. | The Annals of thoracic surgery 20060601 |
| Differential effects of different statins on endothelin-1 gene expression and endothelial NOS phosphorylation in porcine aortic endothelial cells. | Experimental biology and medicine (Maywood, N.J.) 20060601 |
| Pravastatin, simvastatin, and atorvastatin appear equally effective for preventing cardiovascular events. | Evidence-based cardiovascular medicine 20060601 |
| Effects of preoperative statin therapy on cytokines after cardiac surgery. | The Thoracic and cardiovascular surgeon 20060601 |
| The clinical relevance of low-density-lipoproteins size modulation by statins. | Cardiovascular drugs and therapy 20060601 |
| Cost-effectiveness of cholesterol-lowering therapy with pravastatin in patients with previous acute coronary syndromes aged 65 to 74 years compared with younger patients: results from the LIPID study. | American heart journal 20060601 |
| Long-term safety and effectiveness of statins for heart transplant recipients in routine clinical practice. | Transplantation proceedings 20060601 |
| Statins: beneficial or adverse for glucose metabolism. | Journal of atherosclerosis and thrombosis 20060601 |
| Rosuvastatin 5 and 10 mg/d: a pilot study of the effects in hypercholesterolemic adults unable to tolerate other statins and reach LDL cholesterol goals with nonstatin lipid-lowering therapies. | Clinical therapeutics 20060601 |
| Apolipoprotein-E polymorphism and response to pravastatin in men with coronary artery disease (REGRESS). | Acta cardiologica 20060601 |
| [Myocardial dysfunction]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060601 |
| Does pravastatin safely and effectively improve lipid profiles in children who have received a kidney transplant? | Nature clinical practice. Nephrology 20060601 |
| Lipoprotein-associated phospholipase A2, vascular inflammation and cardiovascular risk prediction. | Vascular health and risk management 20060601 |
| Plant sterols as dietary adjuvants in the reduction of cardiovascular risk: theory and evidence. | Vascular health and risk management 20060601 |
| Fenofibrate: a novel formulation (Triglide) in the treatment of lipid disorders: a review. | International journal of nanomedicine 20060601 |
| Statin use and breast cancer: prospective results from the Women's Health Initiative. | Journal of the National Cancer Institute 20060517 |
| Relationship between cardiovascular risk factors and atherosclerotic disease burden measured by intravascular ultrasound. | Journal of the American College of Cardiology 20060516 |
| [Therapeutic effects of pravastatin on colitis induced by acetic acid and relevant mechanism: experiment with rats]. | Zhonghua yi xue za zhi 20060516 |
| Orange juice increased the bioavailability of pravastatin, 3-hydroxy-3-methylglutaryl CoA reductase inhibitor, in rats and healthy human subjects. | Life sciences 20060508 |
| Oxidized low-density lipoprotein in children with familial hypercholesterolemia and unaffected siblings: effect of pravastatin. | Journal of the American College of Cardiology 20060502 |
| Statins and stroke: current clinical practice. | Stroke 20060501 |
| The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons. | Journal of neurochemistry 20060501 |
| Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study). | The American journal of cardiology 20060501 |
| Involvement of 2-C-methyl-D-erythritol-4-phosphate pathway in biosynthesis of aphidicolin-like tetracyclic diterpene of Scoparia dulcis. | Chemical & pharmaceutical bulletin 20060501 |
| Impact of the SLCO1B1 polymorphism on the pharmacokinetics and lipid-lowering efficacy of multiple-dose pravastatin. | Clinical pharmacology and therapeutics 20060501 |
| Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril. | Clinical pharmacology and therapeutics 20060501 |
| A switch in time saves more than nine. Two popular statins, Pravachol and Zocor, go generic this summer, paving the way for significant savings. | Harvard heart letter : from Harvard Medical School 20060501 |
| Statins in patients with chronic kidney disease: evidence from systematic reviews and randomized clinical trials. | PLoS medicine 20060501 |
| Drug and medical cost effects of a drug formulary change with therapeutic interchange for statin drugs in a multistate managed Medicaid organization. | Journal of managed care pharmacy : JMCP 20060501 |
| [Statin therapy: cost-effectiveness and evaluation of evidence as criterium for improving expenditure within the National Health Program]. | Recenti progressi in medicina 20060501 |
| Is atorvastatin superior to other statins? Analysis of the clinical trials with atorvastatin having cardiovascular endpoints. | Reviews on recent clinical trials 20060501 |
| Hydroxymethylglutaryl-coenzyme A reductase inhibitors induce apoptosis in human cardiac myocytes in vitro. | Biochemical pharmacology 20060428 |
| Effect of pravastatin on body composition and markers of cardiovascular disease in HIV-infected men--a randomized, placebo-controlled study. | AIDS (London, England) 20060424 |
| Statins in HIV-associated lipodystrophy and metabolic syndrome: is there a missing link? | AIDS (London, England) 20060424 |
| Statin safety: a systematic review. | The American journal of cardiology 20060417 |
| Effects of colesevelam hydrochloride on low-density lipoprotein cholesterol and high-sensitivity C-reactive protein when added to statins in patients with hypercholesterolemia. | The American journal of cardiology 20060415 |
| Lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin Or atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction) trial. | Circulation 20060411 |
| [Treatment of dyslipoproteinemia in chronic renal failure]. | MMW Fortschritte der Medizin 20060406 |
| Effect of pravastatin, simvastatin and atorvastatin on the phagocytic activity of mouse peritoneal macrophages. | Experimental and molecular pathology 20060401 |
| Changes of plasma inflammatory markers after withdrawal of statin therapy in patients with hyperlipidemia. | Clinica chimica acta; international journal of clinical chemistry 20060401 |
| Pitavastatin effect on ATP binding cassette A1-mediated lipid efflux from macrophages: evidence for liver X receptor (LXR)-dependent and LXR-independent mechanisms of activation by cAMP. | The Journal of pharmacology and experimental therapeutics 20060401 |
| Progression of cerebral white matter lesions is not associated with development of depressive symptoms in elderly subjects at risk of cardiovascular disease: The PROSPER Study. | International journal of geriatric psychiatry 20060401 |
| Chronic kidney disease: a public health problem that needs a public health action plan. | Preventing chronic disease 20060401 |
| Effect of rosuvastatin compared with other statins on lipid levels and National Cholesterol Education Program goal attainment for low-density lipoprotein cholesterol in a usual care setting. | Pharmacotherapy 20060401 |
| Influence of the SLCO1B1*1b and *5 haplotypes on pravastatin's cholesterol lowering capabilities and basal sterol serum levels. | Naunyn-Schmiedeberg's archives of pharmacology 20060401 |
| [Statin treatment in patients with acute coronary syndrome]. | Nihon rinsho. Japanese journal of clinical medicine 20060401 |
| Drug utilization of ezetimibe in rehabilitation centres: registry analysis of factors influencing prescription and effectiveness of treatment. | Current medical research and opinion 20060401 |
| Influences of statins on glucose tolerance in patients with type 2 diabetes mellitus. | Journal of atherosclerosis and thrombosis 20060401 |
| Retrospective review of sex differences in the management of dyslipidemia in coronary heart disease: an analysis of patient data from a Maryland-based health maintenance organization. | Clinical therapeutics 20060401 |
| [Infiltrative lung disease with alveolar density on x-ray: observation]. | Revue des maladies respiratoires 20060401 |
| Pharmacokinetic interaction between nelfinavir and pravastatin in HIV-seronegative volunteers: ACTG Study A5108. | AIDS (London, England) 20060321 |
| A tale of two trials: a comparison of the post-acute coronary syndrome lipid-lowering trials A to Z and PROVE IT-TIMI 22. | Circulation 20060321 |
| Direct comparison of the A to Z and PROVE IT trials: a second chance to gain a first impression. | Circulation 20060321 |
| Effect of statin treatment on coronary collateral development in patients with diabetes mellitus. | The American journal of cardiology 20060315 |
| Statins and nitric oxide reduce C-reactive protein production while inflammatory conditions persist. | Molecular immunology 20060301 |
| Analysis of five HMG-CoA reductase inhibitors-- atorvastatin, lovastatin, pravastatin, rosuvastatin and simvastatin: pharmacological, pharmacokinetic and analytical overview and development of a new method for use in pharmaceutical formulations analysis and in vitro metabolism studies. | Biomedical chromatography : BMC 20060301 |
| Brain cholesterol synthesis in mice is affected by high dose of simvastatin but not of pravastatin. | The Journal of pharmacology and experimental therapeutics 20060301 |
| Pravastatin inhibits expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in Watanabe heritable hyperlipidemic rabbits: a new pleiotropic effect of statins. | Arteriosclerosis, thrombosis, and vascular biology 20060301 |
| Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport. | Pharmaceutical research 20060301 |
| HMG-CoA reductase inhibitors induce apoptosis in pericytes. | Microvascular research 20060301 |
| Effects of various statins on cytokine-dependent growth and IgE-dependent release of histamine in human mast cells. | Allergy 20060301 |
| Effect of cyclosporin A on the biliary excretion of cholephilic compounds in rats. | Hepatology research : the official journal of the Japan Society of Hepatology 20060301 |
| Evidence-based prescribing of statins: a developing world perspective. | PLoS medicine 20060301 |
| Low high-density lipoprotein cholesterol and cardiovascular disease: risk reduction with statin therapy. | American heart journal 20060301 |
| Increased inflammatory markers in children with familial hypercholesterolaemia. | European journal of clinical investigation 20060301 |
| Localized rhabdomyolysis after exertion in a cardiac transplant recipient on statin therapy. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060301 |
| Rapid identification of three functionally relevant polymorphisms in the OATP1B1 transporter gene using Pyrosequencing. | Pharmacogenomics 20060301 |
| Hydroxymethylglutaryl-CoA reductase inhibitors in older persons with acute myocardial infarction: evidence for an age-statin interaction. | Journal of the American Geriatrics Society 20060301 |
| Statin-associated myasthenia gravis: report of 4 cases and review of the literature. | Medicine 20060301 |
| Processing of amyloid precursor protein as a biochemical link between atherosclerosis and Alzheimer's disease. | Cardiovascular & hematological disorders drug targets 20060301 |
| Cost-effectiveness of screening for albuminuria with subsequent fosinopril treatment to prevent cardiovascular events: A pharmacoeconomic analysis linked to the prevention of renal and vascular endstage disease (PREVEND) study and the prevention of renal and vascular endstage disease intervention trial (PREVEND IT). | Clinical therapeutics 20060301 |
| Treatment of hypercholesterolemia in patients with metabolic syndrome: how do different statins compare? | Nature clinical practice. Endocrinology & metabolism 20060301 |
| Treatment of severe sepsis: where next? Current and future treatment approaches after the introduction of drotrecogin alfa. | Vascular health and risk management 20060301 |
| Complementary therapy to target LDL cholesterol: the role of the ezetimibe/simvastatin combination. | Vascular health and risk management 20060301 |
| Evaluation of efficacy and safety of fixed dose lovastatin and niacin(ER) combination in asian Indian dyslipidemic patients: a multicentric study. | Vascular health and risk management 20060301 |
| Telithromycin in the treatment of acute bacterial sinusitis, acute exacerbations of chronic bronchitis, and community-acquired pneumonia. | Therapeutics and clinical risk management 20060301 |
| [Effect of pravastatin on cholesteryl esters in foam cells and the relation with caveolin-1]. | Sheng li xue bao : [Acta physiologica Sinica] 20060225 |
| Formal enantioselective synthesis of (+)-compactin. | Organic letters 20060216 |
| Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure. | Cardiovascular research 20060215 |
| Statins induce calcium-dependent mitochondrial permeability transition. | Toxicology 20060215 |
| Improving effect of ethyl eicosapentanoate on statin-induced rhabdomyolysis in Eisai hyperbilirubinemic rats. | Biochemical and biophysical research communications 20060203 |
| The prion protein requires cholesterol for cell surface localization. | Molecular and cellular neurosciences 20060201 |
| Pharmacogenetics: progress, pitfalls and clinical potential for coronary heart disease. | Vascular pharmacology 20060201 |
| Is there an interaction between pravastatin and clinical events other than vasospasm in patients with aneurysmal subarachnoid hemorrhage? | Stroke 20060201 |
| Pravastatin-induced lichenoid drug eruption. | The Australasian journal of dermatology 20060201 |
| Activators of the energy sensing kinase AMPK inhibit random cell movement and chemotaxis in U937 cells. | Immunology and cell biology 20060201 |
| Increase in periventricular white matter hyperintensities parallels decline in mental processing speed in a non-demented elderly population. | Journal of neurology, neurosurgery, and psychiatry 20060201 |
| Use of hydroxy-methyl-glutaryl coenzyme A reductase inhibitors is associated with risk of lymphoid malignancies. | Cancer science 20060201 |
| Are statins created equal? Evidence from randomized trials of pravastatin, simvastatin, and atorvastatin for cardiovascular disease prevention. | American heart journal 20060201 |
| Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis. | Arthritis and rheumatism 20060201 |
| 'Anti-inflammatory' drugs and their effects on type 2 diabetes. | Diabetes technology & therapeutics 20060201 |
| Serum noncholesterol sterols in children with heterozygous familial hypercholesterolemia undergoing pravastatin therapy. | The Journal of pediatrics 20060201 |
| [Statins in patients with kidney failure: efficacy, tolerance, and prescription guidelines in patients with chronic kidney disease and renal transplant]. | Presse medicale (Paris, France : 1983) 20060201 |
| Pravastatin attenuates tourniquet-induced skeletal muscle ischemia reperfusion injury. | Acta orthopaedica 20060201 |
| Letter regarding article by Tonelli et al, 'effect of pravastatin on rate of kidney function loss in people with or at risk for coronary disease'. | Circulation 20060131 |
| [Recurrent acute pancreatitis during pravastatin-therapy]. | Praxis 20060125 |
| Comparison of effects of pravastatin and hormone therapy on soluble P-selectin and platelet P-selectin expression in postmenopausal hypercholesterolemic women. | Maturitas 20060120 |
| Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway. | Blood 20060115 |
| Cholecystokinin stimulates the recruitment of the Src-RhoA-phosphoinositide 3-kinase pathway by Vav-2 downstream of G(alpha13) in pancreatic acini. | Biochemical and biophysical research communications 20060106 |
| Statins for high-risk patients without heart disease or high cholesterol. | The Medical letter on drugs and therapeutics 20060102 |
| Effects of statins on endothelial function and lipid profile in HIV infected persons receiving protease inhibitor-containing anti-retroviral combination therapy: a randomised double blind crossover trial. | Heart (British Cardiac Society) 20060101 |
| Protective role of pravastatin in the pathogenesis of the metabolic syndrome. | Medical hypotheses 20060101 |
| HMG-CoA reductase inhibitors upregulate heme oxygenase-1 expression in murine RAW264.7 macrophages via ERK, p38 MAPK and protein kinase G pathways. | Cellular signalling 20060101 |
| Determinants of the differences in LDL-cholesterol after initiation of statin treatment. | The Annals of pharmacotherapy 20060101 |
| Effects of pravastatin on the in vitro phagocytic function and hydrogen peroxide production by monocytes of healthy individuals. | International immunopharmacology 20060101 |
| Electrochemical properties and square-wave voltammetric determination of pravastatin. | Analytical and bioanalytical chemistry 20060101 |
| A cost evaluation of the Georgia Stroke and Heart Attack Prevention Program. | Preventing chronic disease 20060101 |
| Preoperative statin therapy and troponin T predict early complications of coronary artery surgery. | The Annals of thoracic surgery 20060101 |
| Pharmacological strategies for the prevention of Alzheimer's disease. | Expert opinion on pharmacotherapy 20060101 |
| Effect of pravastatin on plasma sterols and oxysterols in men. | European journal of clinical pharmacology 20060101 |
| Statins and osteoporosis: new role for old drugs. | The Journal of pharmacy and pharmacology 20060101 |
| Plasma LDL and HDL characteristics and carotenoid content are positively influenced by egg consumption in an elderly population. | Nutrition & metabolism 20060101 |
| Statins decrease serotonin-induced contractions in coronary arteries of swine in vitro. | Pharmacology 20060101 |
| Ezetimibe for the treatment of uncontrolled hypercholesterolemia in patients with high-dose statin therapy after renal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101 |
| Muscle symptoms associated with statins: a series of twenty patients. | Basic & clinical pharmacology & toxicology 20060101 |
| Time course of rapid C-reactive protein reduction by pravastatin in patients with stable angina. | Angiology 20060101 |
| Statin wars following coronary revascularization--evidence-based clinical practice? | The Canadian journal of cardiology 20060101 |
| C-reactive protein levels and outcomes after statin therapy. | Current atherosclerosis reports 20060101 |
| Pravastatin and clopidogrel combined inhibit intimal hyperplasia in a rat carotid endarterectomy model. | Vascular and endovascular surgery 20060101 |
| Effect of pravastatin and atorvastatin on glucose metabolism in nondiabetic patients with hypercholesterolemia. | Internal medicine (Tokyo, Japan) 20060101 |
| Statin-related adverse events: a meta-analysis. | Clinical therapeutics 20060101 |
| Endothelial dysfunction: a comprehensive appraisal. | Cardiovascular diabetology 20060101 |
| The statins: drug interactions of significance to the dental practitioner. | Dental update 20060101 |
| [Prevention of the manifestation of diabetes in the elderly in the presymptomatic stage]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20060101 |
| Who should receive statin therapy among the elderly? | The American journal of geriatric cardiology 20060101 |
| Circle of Willis variation in a complex stroke presentation: a case report. | BMC neurology 20060101 |
| Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1. | Saline systems 20060101 |
| Comparative study on the bioequivalence of two formulations of pravastatin. Data from a crossover, randomised, open-label bioequivalence study in healthy volunteers. | Arzneimittel-Forschung 20060101 |
| Action of Lovastatin (Mevinolin) on an in vitro model of angiogenesis and its co-culture with malignant melanoma cell lines. | Cancer cell international 20060101 |
| Basilar artery dolichoectasia with partial thrombosis. | Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20060101 |
| Effect of probucol on elderly hypercholesterolemic patients in the FAST study. | Fukuoka igaku zasshi = Hukuoka acta medica 20060101 |
| Revascularization and cardioprotective drug treatment in myocardial infarction patients: how do they impact on patients' survival when delivered as usual care. | BMC cardiovascular disorders 20060101 |
| The fading of reported effectiveness. A meta-analysis of randomised controlled trials. | BMC medical research methodology 20060101 |
| Prevention of positive coronary artery remodeling with statin therapy in patients with coronary artery diseases. | Angiology 20060101 |
| Biliary excretion of sulfated bile acids and organic anions in zone 1- and zone 3-injured rats. | Journal of gastroenterology and hepatology 20060101 |
| Vascular endothelial growth factor serum concentrations in hypercholesterolemic patients. | Scandinavian journal of clinical and laboratory investigation 20060101 |
| A randomized trial to assess the impact of opinion leader endorsed evidence summaries on the use of secondary prevention strategies in patients with coronary artery disease: the ESP-CAD trial protocol [NCT00175240]. | Implementation science : IS 20060101 |
| Assessing health state utilities in elderly patients at cardiovascular risk. | Medical decision making : an international journal of the Society for Medical Decision Making 20060101 |
| Modular prevention of heart disease following acute coronary syndrome (ACS) [ISRCTN42984084]. | BMC cardiovascular disorders 20060101 |
| Cost-effectiveness analysis of cholesterol-lowering therapies in Spain. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101 |
| Comparison between mevinolin and PTH action on MG63 osteoblast-like cells. | Biomedical sciences instrumentation 20060101 |
| Gemcitabine in combination with EGF-Receptor antibody (Cetuximab) as a treatment of cholangiocarcinoma: a case report. | BMC cancer 20060101 |
| Haemostasis, inflammation and renal function following exercise in patients with intermittent claudication on statin and aspirin therapy. | Thrombosis journal 20060101 |
| Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis. | Arthritis research & therapy 20060101 |
| Inhibitory effect of statins on renal epithelial-to-mesenchymal transition. | American journal of nephrology 20060101 |
| Development and testing of innovative patient resources for the management of coronary heart disease (CHD): a descriptive study. | BMC health services research 20060101 |
| [Do statins have a place for cardiovascular prevention in elderly people?]. | Revue medicale de Liege 20060101 |
| Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy. | Journal of human genetics 20060101 |
| Population variation and differences in serum leptin independent of adiposity: a comparison of Ache Amerindian men of Paraguay and lean American male distance runners. | Nutrition & metabolism 20060101 |
| Statins of different brain penetrability differentially affect CSF PLTP activity. | Dementia and geriatric cognitive disorders 20060101 |
| Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease. | Journal of biomedicine & biotechnology 20060101 |
| Changes in practice patterns affecting in-hospital and post-discharge survival among ACS patients. | BMC health services research 20060101 |
| Lipid lowering therapy in the elderly: is there a benefit? | Current pharmaceutical design 20060101 |
| Autosomal recessive cerebellar ataxias. | Orphanet journal of rare diseases 20060101 |
| Effects of pravastatin treatment on blood pressure regulation after renal transplantation. | Kidney & blood pressure research 20060101 |
| Drug-herb interactions: eliminating toxicity with hard drug design. | Current pharmaceutical design 20060101 |
| A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle. | PloS one 20060101 |
| Comparison of the efficacy and safety of rosuvastatin 10 mg and atorvastatin 20 mg in high-risk patients with hypercholesterolemia--Prospective study to evaluate the Use of Low doses of the Statins Atorvastatin and Rosuvastatin (PULSAR). | Trials 20060101 |
| Effect of olmesartan medoxomil on atherosclerosis: clinical implications of the emerging evidence. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101 |
| [C-reactive protein in cardiovascular diseases]. | Przeglad lekarski 20060101 |
| Generic pravastatin approved. | FDA consumer 20060101 |
| Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials. | Chinese medicine 20060101 |
| Changes in cholesterol metabolism are associated with PS1 and PS2 gene regulation in SK-N-BE. | Journal of molecular neuroscience : MN 20060101 |
| [The effect of statins on lipids peroxidation and activities of antioxidants enzymes in patients with dyslipidemia]. | Przeglad lekarski 20060101 |
| Lipid-modifying and pleiotropic effects of gemfibrozil, simvastatin and pravastatin in patients with dyslipidemia. | Folia medica 20060101 |
| Serum lipid profile constituents as markers of cardiovascular morbidity in patients on chronic hemodialysis. | Biomarker insights 20060101 |
| Effect of atorvastatin (80 mg/day) versus pravastatin (40 mg/day) on arterial remodeling at coronary branch points (from the REVERSAL study). | The American journal of cardiology 20051215 |
| Stabilization of carotid atheroma assessed by quantitative ultrasound analysis in nonhypercholesterolemic patients with coronary artery disease. | Journal of the American College of Cardiology 20051206 |
| Statins prevent beta-amyloid inhibition of sympathetic alpha7-nAChR-mediated nitrergic neurogenic dilation in porcine basilar arteries. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051201 |
| Effect of pravastatin in people with diabetes and chronic kidney disease. | Journal of the American Society of Nephrology : JASN 20051201 |
| Prospective monitoring of lipid profiles in children receiving pravastatin preemptively after renal transplantation. | Pediatric transplantation 20051201 |
| Underutilization of aspirin persists in US ambulatory care for the secondary and primary prevention of cardiovascular disease. | PLoS medicine 20051201 |
| Effect of statin use in patients with acute coronary syndromes and a serum low-density lipoprotein<or=80 mg/dl. | The American journal of cardiology 20051201 |
| Antihyperlipidaemic effect of a Monascus purpureus brand dietary supplement on a large sample of subjects at low risk for cardiovascular disease: a pilot study. | Complementary therapies in medicine 20051201 |
| Does pravastatin increase chylomicron remnant catabolism in postmenopausal women with type 2 diabetes mellitus? | Clinical endocrinology 20051201 |
| Achieving lipid goals in real life: the Dutch DISCOVERY study. | International journal of clinical practice 20051201 |
| Halting the progression of atherosclerosis with intensive lipid lowering: results from the Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial. | The American journal of medicine 20051201 |
| Improved outcome after acute coronary syndromes with an intensive versus standard lipid-lowering regimen: results from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) trial. | The American journal of medicine 20051201 |
| What impact will current trial data have on future guideline recommendations? | The American journal of medicine 20051201 |
| The ability of statins to protect low density lipoprotein from oxidation in hypercholesterolemic patients. | International journal of clinical pharmacology and therapeutics 20051201 |
| [Fluvastatin-induced dermatomyositis]. | Annales de dermatologie et de venereologie 20051201 |
| Renoprotective effect of pravastatin in salt-loaded Dahl salt-sensitive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20051201 |
| Optimal lipid modification: the rationale for combination therapy. | Vascular health and risk management 20051201 |
| Efficacy and safety of atorvastatin in South Asian patients with dyslipidemia: an open label noncomparative pilot study. | Vascular health and risk management 20051201 |
| Are statins being underdosed in clinical practice? Data from TACTICS-TIMI 18. | Critical pathways in cardiology 20051201 |
| [Significance of cholesterol levels in patients 75 years or older]. | Presse medicale (Paris, France : 1983) 20051119 |
| Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER). | Circulation 20051115 |
| Low-density lipoprotein receptor genotype and response to pravastatin in children with familial hypercholesterolemia: substudy of an intima-media thickness trial. | Circulation 20051115 |
| [How can lipid therapy be improved? Cardiologists insist on dual cholesterol inhibition]. | MMW Fortschritte der Medizin 20051110 |
| The effect of six different statins on the proliferation, migration, and invasion of human smooth muscle cells. | The Journal of surgical research 20051101 |
| The effect of pravastatin on intima media thickness of the carotid artery in patients with normal cholesterol. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20051101 |
| Disposition of oral and intravenous pravastatin in MRP2-deficient TR- rats. | Drug metabolism and disposition: the biological fate of chemicals 20051101 |
| [Pravastatin-induced dermatomyositis]. | La Revue de medecine interne 20051101 |
| Systemic inflammatory markers in acute coronary syndrome: association with cardiovascular risk factors and effect of early lipid lowering. | Coronary artery disease 20051101 |
| Optimal goals for statin use in patients with coronary artery disease. | Current opinion in cardiology 20051101 |
| Evaluation of the paraoxonases as candidate genes for stroke: Gln192Arg polymorphism in the paraoxonase 1 gene is associated with increased risk of stroke. | Stroke 20051101 |
| A novel nitric oxide-releasing statin derivative exerts an antiplatelet/antithrombotic activity and inhibits tissue factor expression. | Journal of thrombosis and haemostasis : JTH 20051101 |
| Intensity of lipid lowering with statins and brachial artery vascular endothelium reactivity after acute coronary syndromes (from the BRAVER trial). | The American journal of cardiology 20051101 |
| X-Hitting: an algorithm for novelty detection and dereplication by UV spectra of complex mixtures of natural products. | Analytical chemistry 20051101 |
| Statin-induced apoptosis linked with membrane farnesylated Ras small G protein depletion, rather than geranylated Rho protein. | The Journal of pharmacy and pharmacology 20051101 |
| Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment. | Cellular and molecular life sciences : CMLS 20051101 |
| Myonecrosis after elective percutaneous coronary intervention: effect of clopidogrel-statin interaction. | The Journal of invasive cardiology 20051101 |
| The effect of switching on compliance and persistence: the case of statin treatment. | The American journal of managed care 20051101 |
| HMG-CoA reductase inhibitors do not improve glucose intolerance in spontaneously diabetic Goto-Kakizaki rats. | Biological & pharmaceutical bulletin 20051101 |
| Differential associations of statin and fibrate treatment with carotid arterial remodeling. | American journal of hypertension 20051101 |
| Ten-year follow-up of a randomized trial of pravastatin in heart transplant patients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051101 |
| In-hospital initiation of statin therapy in acute coronary syndromes: maximizing the early and long-term benefits. | Chest 20051101 |
| Pravastatin reduces thrombogenicity by mechanisms beyond plasma cholesterol lowering. | Thrombosis and haemostasis 20051101 |
| Safety of statins when response is carefully monitored: a study of 336 heart recipients. | Transplantation proceedings 20051101 |
| The benefits of statin therapy--what questions remain? | Clinical cardiology 20051101 |
| Relation between serum phosphate level and cardiovascular event rate in people with coronary disease. | Circulation 20051025 |
| Pravastatin suppresses the increase in matrix metalloproteinase-2 levels after acute myocardial infarction. | International journal of cardiology 20051020 |
| Early and late benefits of high-dose atorvastatin in patients with acute coronary syndromes: results from the PROVE IT-TIMI 22 trial. | Journal of the American College of Cardiology 20051018 |
| Can low-density lipoprotein be too low? The safety and efficacy of achieving very low low-density lipoprotein with intensive statin therapy: a PROVE IT-TIMI 22 substudy. | Journal of the American College of Cardiology 20051018 |
| Relationship between uncontrolled risk factors and C-reactive protein levels in patients receiving standard or intensive statin therapy for acute coronary syndromes in the PROVE IT-TIMI 22 trial. | Journal of the American College of Cardiology 20051018 |
| The potential relevance of the multiple lipid-independent (pleiotropic) effects of statins in the management of acute coronary syndromes. | Journal of the American College of Cardiology 20051018 |
| Barriers to a trial of atherosclerosis prevention in systemic lupus erythematosus. | Arthritis and rheumatism 20051015 |
| Effect of pravastatin on malondialdehyde-modified low-density lipoprotein levels and coronary plaque regression as determined by three-dimensional intravascular ultrasound. | The American journal of cardiology 20051015 |
| Beneficial effects of atorvastatin on sd LDL and LDL phenotype B in statin-naive patients and patients previously treated with simvastatin or pravastatin. | International journal of cardiology 20051010 |
| Pravastatin activates platelet nitric oxide synthase (NOS) in patients with type 2 diabetes mellitus and NOS activation is accompanied by serine phosphorylation. | Chinese medical journal 20051005 |
| The forgotten majority: unfinished business in cardiovascular risk reduction. | Journal of the American College of Cardiology 20051004 |
| Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells. | Brain research. Molecular brain research 20051003 |
| In vitro effect of statins on cytokine production and mitogen response of human peripheral blood mononuclear cells. | Clinical immunology (Orlando, Fla.) 20051001 |
| Short-term reduction in bone markers with high-dose simvastatin. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20051001 |
| Persistence and determinants of statin therapy among middle-aged patients free of cardiovascular disease. | European journal of clinical pharmacology 20051001 |
| Effect of combined treatment with an angiotensin II receptor antagonist and an HMG-CoA reductase inhibitor on atherosclerosis in genetically hyperlipidemic rabbits. | Journal of cardiovascular pharmacology 20051001 |
| Achievement of English National Service Framework lipid-lowering goals: pooled data from recent comparative treatment trials of statins at starting doses. | International journal of clinical practice 20051001 |
| Apical/basolateral surface expression of drug transporters and its role in vectorial drug transport. | Pharmaceutical research 20051001 |
| Effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on high-sensitivity C-reactive protein levels. | Pharmacotherapy 20051001 |
| Hydrophilic statin suppresses vein graft intimal hyperplasia via endothelial cell-tropic Rho-kinase inhibition. | Journal of vascular surgery 20051001 |
| Different effect of statins on platelet oxidized-LDL receptor (CD36 and LOX-1) expression in hypercholesterolemic subjects. | Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20051001 |
| Statins modulate the levels of osteoprotegerin/receptor activator of NFkappaB ligand mRNA in mouse bone-cell cultures. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001 |
| The long-term course of low-density lipoprotein cholesterol after initiation of statin treatment: retrospective database analysis over 3 years in health maintenance organization enrollees. | Clinical therapeutics 20051001 |
| [Hypolipidemic treatment under special conditions: posttransplant and/or immunosuppressive therapy]. | Arquivos brasileiros de cardiologia 20051001 |
| [Hypolipidemic therapy under special conditions: acquired immune deficiency syndrome]. | Arquivos brasileiros de cardiologia 20051001 |
| Cost-effectiveness of pravastatin for primary prevention of coronary artery disease in Japan. | International journal of cardiology 20050930 |
| Evaluation of apoptosis and necrosis induced by statins using fluorescence-enhanced flow cytometry. | Journal of pharmaceutical and biomedical analysis 20050915 |
| Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. | Journal of molecular biology 20050909 |
| Binding thermodynamics of statins to HMG-CoA reductase. | Biochemistry 20050906 |
| Review of primary and secondary prevention trials with lovastatin, pravastatin, and simvastatin. | The American journal of cardiology 20050905 |
| The case for intensive statin therapy after acute coronary syndromes. | The American journal of cardiology 20050905 |
| Early time to benefit with intensive statin treatment: could it be the pleiotropic effects? | The American journal of cardiology 20050905 |
| Effect of intensive lipid lowering on progression of coronary atherosclerosis: evidence for an early benefit from the Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial. | The American journal of cardiology 20050905 |
| Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein. | The Journal of pharmacology and experimental therapeutics 20050901 |
| Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin. | Molecular pharmacology 20050901 |
| The effect of statin therapy on lipoprotein associated phospholipase A2 levels. | Atherosclerosis 20050901 |
| Statin-macrolide interaction risk: a population-based study throughout a general practice database. | European journal of clinical pharmacology 20050901 |
| Does statin monotherapy address the multiple lipid abnormalities in type 2 diabetes? | Atherosclerosis. Supplements 20050901 |
| Combined therapy with atorvastatin and calcineurin inhibitors: no interactions with tacrolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901 |
| REVERSAL and PROVE-IT: are clinically oriented trials really better than 'pure' scientific studies? | International journal of cardiology 20050901 |
| The -514C/T polymorphism of the hepatic lipase gene significantly modulates the HDL-cholesterol response to statin treatment. | Atherosclerosis 20050901 |
| Lowering of elevated ambulatory blood pressure by HMG-CoA reductase inhibitors. | Journal of cardiovascular pharmacology 20050901 |
| The pharmacological potential of mushrooms. | Evidence-based complementary and alternative medicine : eCAM 20050901 |
| Survival, graft atherosclerosis, and rejection incidence in heart transplant recipients treated with statins: 5-year follow-up. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050901 |
| [HIV infection, antiretroviral therapy, and endothelium]. | Herz 20050901 |
| Lipid-modifying therapy and attainment of cholesterol goals in Europe: the Return on Expenditure Achieved for Lipid Therapy (REALITY) study. | Current medical research and opinion 20050901 |
| Differences between statins on clinical endpoints: a population-based cohort study. | Current medical research and opinion 20050901 |
| The prevention of type 2 diabetes: what is the evidence? | Minerva endocrinologica 20050901 |
| A randomized trial of the efficacy and safety of fenofibrate versus pravastatin in HIV-infected subjects with lipid abnormalities: AIDS Clinical Trials Group Study 5087. | AIDS research and human retroviruses 20050901 |
| Stroke prevention, blood cholesterol and statins. | Acta neurologica Taiwanica 20050901 |
| A case of familial hypercholesterolemia; secession from LDL-apheresis by the drug treatment with potent statin and resin. | The Tokai journal of experimental and clinical medicine 20050901 |
| Increase in plasma malondialdehyde-modified low-density lipoprotein in patients with atherothrombotic cerebral infarction. | The Tokai journal of experimental and clinical medicine 20050901 |
| [The effects of pravastatin on platelet-derived nitric oxide system in rabbits]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20050901 |
| Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome. | Vascular health and risk management 20050901 |
| Actions of calcium channel blockers on vascular proteoglycan synthesis: relationship to atherosclerosis. | Vascular health and risk management 20050901 |
| Premature coronary artery disease in Indians and its associated risk factors. | Vascular health and risk management 20050901 |
| Impact of the pravastatin or atorvastatin evaluation and infection therapy-thrombolysis in myocardial infarction 22/Reversal of Atherosclerosis with Aggressive Lipid Lowering trials on trends in intensive versus moderate statin therapy in Ontario, Canada. | Circulation 20050830 |
| Rationale for new American Diabetes Association Guidelines: are national cholesterol education program goals adequate for the patient with diabetes mellitus? | The American journal of cardiology 20050822 |
| [Intensive LDL lowering to under 80 mg/dl: hypercholesteremia patients with stable coronary disease and diabetes profit especially significantly]. | MMW Fortschritte der Medizin 20050818 |
| Effect of statins on the proteasomal activity in mammalian endothelial and vascular smooth muscle cells. | Biochemical pharmacology 20050815 |
| Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells. | British journal of cancer 20050808 |
| Fast analysis of pravastatin in production media. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050805 |
| Functional involvement of rat organic anion transporter 2 (Slc22a7) in the hepatic uptake of the nonsteroidal anti-inflammatory drug ketoprofen. | Drug metabolism and disposition: the biological fate of chemicals 20050801 |
| Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin. | The Journal of pharmacology and experimental therapeutics 20050801 |
| Hydroxymethylglutaryl co-enzyme A reductase inhibition attenuates endotoxin-mediated inflammatory responses. | The British journal of surgery 20050801 |
| Comparison of the effects of pravastatin and atorvastatin on fracture incidence in the PROVE IT-TIMI 22 trial--secondary analysis of a randomized controlled trial. | Bone 20050801 |
| Genomic effect of vitamin 'C' and statins within human mononuclear cells involved in atherogenic process. | European journal of clinical nutrition 20050801 |
| Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8. | Basic & clinical pharmacology & toxicology 20050801 |
| Add-on and withdrawal effect of pravastatin on proteinuria in hypertensive patients treated with AT receptor blockers. | Kidney international 20050801 |
| The effects of multiple doses of fenofibrate on the pharmacokinetics of pravastatin and its 3alpha-hydroxy isomeric metabolite. | Journal of clinical pharmacology 20050801 |
| Suppression of Wolffia arrhiza growth by brassinazole, an inhibitor of brassinosteroid biosynthesis and its restoration by endogenous 24-epibrassinolide. | Phytochemistry 20050801 |
| Three-year follow-up results of angiographic intervention trial using an HMG-CoA reductase inhibitor to evaluate retardation of obstructive multiple atheroma (ATHEROMA) study. | Circulation journal : official journal of the Japanese Circulation Society 20050801 |
| Statin use after acute myocardial infarction: a nationwide study in Denmark. | British journal of clinical pharmacology 20050801 |
| Induction of CTGF by TGF-beta1 in normal and radiation enteritis human smooth muscle cells: Smad/Rho balance and therapeutic perspectives. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050801 |
| Effects of acute treatment with pravastatin on cerebral vasospasm, autoregulation, and delayed ischemic deficits after aneurysmal subarachnoid hemorrhage: a phase II randomized placebo-controlled trial. | Stroke 20050801 |
| Lack of effect of pravastatin on cerebral blood flow or parenchymal volume loss in elderly at risk for vascular disease. | Stroke 20050801 |
| Treatment strategies in endothelial dysfunction: physical exercise versus pharmacological therapy. | European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20050801 |
| Effect of mild endurance exercise training and pravastatin on peripheral vasodilatation of forearm resistance vessels in patients with coronary artery disease. | European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20050801 |
| Relating statin therapy to C-reactive protein levels. | Expert opinion on pharmacotherapy 20050801 |
| Not all statins interfere with clopidogrel during antiplatelet therapy. | European journal of clinical investigation 20050801 |
| Effect of short-term treatment with pravastatin on cytokines and cytokine receptors in patients with chronic heart failure due to ischemic and nonischemic disease. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050801 |
| Statins and cancer development. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050801 |
| The antiplatelet effect of clopidogrel is not attenuated by statin treatment in stable patients with ischemic heart disease. | Thrombosis and haemostasis 20050801 |
| New light on statin side effects. What recent research on the cholesterol drugs means to you. | Heart advisor 20050801 |
| Aggressive versus moderate lipid-lowering therapy in hypercholesterolemic postmenopausal women: Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES). | Circulation 20050726 |
| Association between short-term effectiveness of statins and long-term adherence to lipid-lowering therapy. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050715 |
| Effect of pravastatin on rate of kidney function loss in people with or at risk for coronary disease. | Circulation 20050712 |
| Intensive lipid lowering with atorvastatin in coronary disease. | The New England journal of medicine 20050707 |
| Statin treatment after onset of sepsis in a murine model improves survival. | Circulation 20050705 |
| Induction of macrophage elastase (MMP-12) gene expression by statins. | Journal of cellular physiology 20050701 |
| Effect of pravastatin on development of left ventricular hypertrophy in spontaneously hypertensive rats. | American journal of physiology. Heart and circulatory physiology 20050701 |
| Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor. | Drug metabolism and disposition: the biological fate of chemicals 20050701 |
| Impact of statins in microalbuminuric subjects with the metabolic syndrome: a substudy of the PREVEND Intervention Trial. | European heart journal 20050701 |
| Metabolic syndrome criteria: ready for clinical prime time or work in progress? | European heart journal 20050701 |
| Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway. | Journal of the American Society of Nephrology : JASN 20050701 |
| D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null mice. | Arteriosclerosis, thrombosis, and vascular biology 20050701 |
| TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia. | European journal of human genetics : EJHG 20050701 |
| Improved cerebral vasoreactivity after statin administration in healthy adults. | Journal of neuroimaging : official journal of the American Society of Neuroimaging 20050701 |
| Biomarkers of inflammation and progression of chronic kidney disease. | Kidney international 20050701 |
| Comparison of rosuvastatin with atorvastatin, simvastatin and pravastatin in achieving cholesterol goals and improving plasma lipids in hypercholesterolaemic patients with or without the metabolic syndrome in the MERCURY I trial. | Diabetes, obesity & metabolism 20050701 |
| Biliary excretion of taurocholate, organic anions and vinblastine in rats with alpha-naphthylisothiocyanate-induced cholestasis. | Journal of gastroenterology and hepatology 20050701 |
| Substitution of nevirapine or efavirenz for protease inhibitor versus lipid-lowering therapy for the management of dyslipidaemia. | AIDS (London, England) 20050701 |
| Pravastatin does not have a consistent antiviral effect in chronically HIV-infected individuals on antiretroviral therapy. | AIDS (London, England) 20050701 |
| Suboptimal choices and dosing of statins at start of therapy. | British journal of clinical pharmacology 20050701 |
| Cholesterol levels and statin use in patients with coronary heart disease treated in primary care settings. | Preventing chronic disease 20050701 |
| Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells. | Pharmacogenetics and genomics 20050701 |
| Effects of cholesterol-lowering statins on the aqueous humor outflow pathway. | Investigative ophthalmology & visual science 20050701 |
| Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: results of AIDS Clinical Trials Group 5108 Study. | Journal of acquired immune deficiency syndromes (1999) 20050701 |
| Pravastatin does not affect insulin sensitivity and adipocytokines levels in healthy nondiabetic patients. | Metabolism: clinical and experimental 20050701 |
| In vivo and in vitro effects of statins on lymphocytes in patients with Hashimoto's thyroiditis. | European journal of endocrinology 20050701 |
| Rosuvastatin for the treatment of hypercholesterolemia. | Pharmacotherapy 20050701 |
| JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998). | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050701 |
| Volumetric quantitative analysis of tissue characteristics of coronary plaques after statin therapy using three-dimensional integrated backscatter intravascular ultrasound. | Journal of the American College of Cardiology 20050621 |
| Combined effects of losartan and pravastatin on interstitial inflammation and fibrosis in chronic cyclosporine-induced nephropathy. | Transplantation 20050615 |
| The safety of rosuvastatin as used in common clinical practice: a postmarketing analysis. | Circulation 20050614 |
| Genetic variation in the rate-limiting enzyme in cholesterol catabolism (cholesterol 7alpha-hydroxylase) influences the progression of atherosclerosis and risk of new clinical events. | Clinical science (London, England : 1979) 20050601 |
| Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins. | Arteriosclerosis, thrombosis, and vascular biology 20050601 |
| Pravastatin restores DDAH activity and endothelium-dependent relaxation of rat aorta after exposure to glycated protein. | Journal of cardiovascular pharmacology 20050601 |
| Cost effectiveness of rosuvastatin in treating patients to low-density lipoprotein cholesterol goals compared with atorvastatin, pravastatin, and simvastatin (a US Analysis of the STELLAR Trial). | The American journal of cardiology 20050601 |
| Plasma lipoprotein(a) [Lp(a)] concentrations and cardiovascular events in the elderly: evidence from the prospective study of pravastatin in the elderly at risk (PROSPER). | Atherosclerosis 20050601 |
| Effect of pravastatin on progression of coronary atherosclerosis in patients after coronary artery bypass surgery. | Circulation journal : official journal of the Japanese Circulation Society 20050601 |
| Baseline levels of low-density lipoprotein cholesterol and lipoprotein (a) and the AvaII polymorphism of the low-density lipoprotein receptor gene influence the response of low-density lipoprotein cholesterol to pravastatin treatment. | Metabolism: clinical and experimental 20050601 |
| Pravastatin reduces fibrinogen receptor gpIIIa on platelet-derived microparticles in patients with type 2 diabetes. | Journal of thrombosis and haemostasis : JTH 20050601 |
| Cardiovascular risk: prevention and treatment of the metabolic syndrome. | Diabetes research and clinical practice 20050601 |
| HDL-C and the diabetic patient: target for therapeutic intervention? | Diabetes research and clinical practice 20050601 |
| The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells. | Journal of Korean medical science 20050601 |
| Can type 2 diabetes mellitus be considered preventable? | Diabetes research and clinical practice 20050601 |
| Atorvastatin. | Expert opinion on pharmacotherapy 20050601 |
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
| Early effects of statin therapy on endothelial function and microvascular reactivity in patients with coronary artery disease. | American heart journal 20050601 |
| Induction of micronuclei in CHO cells by bleomycin but not by X-irradiation is decreased by treatment with HMG-CoA reductase inhibitors. | Journal of radiation research 20050601 |
| Acute onset and worsening of diabetes concurrent with administration of statins. | Endocrine journal 20050601 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20050601 |
| 4,8-Dimethyldecanal, the aggregation pheromone of Tribolium castaneum, is biosynthesized through the fatty acid pathway. | Journal of chemical ecology 20050601 |
| [Erythrocyte fluidity in patients with hyperlipidemia during statins therapy]. | Polskie Archiwum Medycyny Wewnetrznej 20050601 |
| A new paradigm of cardiovascular risk factor modification. | Vascular health and risk management 20050601 |
| Carotid ultrasound assessment of patients with coronary artery disease: a useful index for risk stratification. | Vascular health and risk management 20050601 |
| Treatment of high blood pressure and gain in event-free life expectancy. | Vascular health and risk management 20050601 |
| Clinical implications of changes in hepatic drug metabolism in older people. | Therapeutics and clinical risk management 20050601 |
| Effect of pravastatin on cerebral infarcts and white matter lesions. | Neurology 20050524 |
| Relative efficacy of atorvastatin 80 mg and pravastatin 40 mg in achieving the dual goals of low-density lipoprotein cholesterol <70 mg/dl and C-reactive protein <2 mg/l: an analysis of the PROVE-IT TIMI-22 trial. | Journal of the American College of Cardiology 20050517 |
| Efficacy and safety of rosuvastatin in treatment of dyslipidemia. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050515 |
| Modulation of regulatory factors involved in cholesterol metabolism in response to feeding of pravastatin- or cholesterol-supplemented diet in chickens. | Biochimica et biophysica acta 20050515 |
| Statins' dosage in patients with renal failure and cyclosporine drug-drug interactions in transplant recipient patients. | International journal of cardiology 20050511 |
| Rapid effect of pravastatin on endothelial function and lipid peroxidation in unstable angina. | International journal of cardiology 20050511 |
| HMG CoA reductase inhibitors (statins) to treat Epstein-Barr virus-driven lymphoma. | British journal of cancer 20050509 |
| Uptake of irinotecan metabolite SN-38 by the human intestinal cell line Caco-2. | Cancer chemotherapy and pharmacology 20050501 |
| Statins activate the mitochondrial pathway of apoptosis in human lymphoblasts and myeloma cells. | Carcinogenesis 20050501 |
| Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-delta. | Arteriosclerosis, thrombosis, and vascular biology 20050501 |
| Pharmacogenetic study of statin therapy and cholesterol reduction. | Current atherosclerosis reports 20050501 |
| Cholesteryl ester transfer protein TaqIB polymorphism in the cholesterol and recurrent events study. | Current atherosclerosis reports 20050501 |
| Effects of atorvastatin versus other statins on fasting and postprandial C-reactive protein and lipoprotein-associated phospholipase A2 in patients with coronary heart disease versus control subjects. | The American journal of cardiology 20050501 |
| Effectiveness of inhibition of cholesteryl ester transfer protein by JTT-705 in combination with pravastatin in type II dyslipidemia. | The American journal of cardiology 20050501 |
| Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses. | Radiation research 20050501 |
| Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat. | Journal of gastroenterology and hepatology 20050501 |
| Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17. | Pharmacogenetics and genomics 20050501 |
| Total first-year costs of acute coronary syndrome in a managed care setting. | Journal of managed care pharmacy : JMCP 20050501 |
| Value for money in disease management of acute coronary syndrome--the price of aspirin to reduce the costs of ACS. | Journal of managed care pharmacy : JMCP 20050501 |
| The beneficial effects of lipid-lowering drugs beyond lipid-lowering effects: a comparative study with pravastatin, atorvastatin, and fenofibrate in patients with type IIa and type IIb hyperlipidemia. | Metabolism: clinical and experimental 20050501 |
| A community-based, randomized trial of ezetimibe added to statin therapy to attain NCEP ATP III goals for LDL cholesterol in hypercholesterolemic patients: the ezetimibe add-on to statin for effectiveness (EASE) trial. | Mayo Clinic proceedings 20050501 |
| National trends in statin use by coronary heart disease risk category. | PLoS medicine 20050501 |
| [Effects of pravastatin, fosinopril and their combination on myocardium TNF-alpha expression and ventricular remodeling after myocardial infarction in rats]. | Zhonghua xin xue guan bing za zhi 20050501 |
| Gitelman's syndrome presenting as intolerance to statin therapy. | Annals of clinical biochemistry 20050501 |
| Pravastatin attenuates ceramide-induced cytotoxicity in mouse cerebral endothelial cells with HIF-1 activation and VEGF upregulation. | Annals of the New York Academy of Sciences 20050501 |
| Cardiac preconditioning during percutaneous coronary interventions. | Cardiovascular drugs and therapy 20050501 |
| Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effect. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050426 |
| Quantification of pravastatin in human plasma and urine after solid phase extraction using high performance liquid chromatography with ultraviolet detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050425 |
| Effects of switching statins on lipid and apolipoprotein ratios in the MERCURY I study. | International journal of cardiology 20050420 |
| Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells. | Biochimica et biophysica acta 20050415 |
| White blood cell count predicts reduction in coronary heart disease mortality with pravastatin. | Circulation 20050412 |
| [The PROVE IT-TIMI-22 study or the biter being bit]. | Revue medicale suisse 20050406 |
| Beneficial effect of simvastatin and pravastatin treatment on adverse cardiac remodelling and glomeruli loss in spontaneously hypertensive rats. | Clinical science (London, England : 1979) 20050401 |
| Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1. | Drug metabolism and disposition: the biological fate of chemicals 20050401 |
| Efficacy and safety of pravastatin in children and adolescents with heterozygous familial hypercholesterolemia: a prospective clinical follow-up study. | The Journal of clinical endocrinology and metabolism 20050401 |
| High doses of simvastatin upregulate dopamine D1 and D2 receptor expression in the rat prefrontal cortex: possible involvement of endothelial nitric oxide synthase. | British journal of pharmacology 20050401 |
| Measurement of saturable and non-saturable components of anandamide uptake into P19 embryonic carcinoma cells in the presence of fatty acid-free bovine serum albumin. | Chemistry and physics of lipids 20050401 |
| Disruption of lipid rafts causes apoptotic cell death in HaCaT keratinocytes. | Experimental dermatology 20050401 |
| Synthesis and structure-activity relationship of 4-substituted benzoic acids and their inhibitory effect on the biosynthesis of fatty acids and sterols. | Archiv der Pharmazie 20050401 |
| Lovastatin-induced apoptosis in human melanoma cell lines. | Melanoma research 20050401 |
| Statin-induced vascular smooth muscle cell apoptosis: a possible role in the prevention of restenosis? | Current drug targets. Cardiovascular & haematological disorders 20050401 |
| Anti-oxidative effect of fluvastatin in hyperlipidemic type 2 diabetic patients. | Endocrine journal 20050401 |
| [Effects of atorvastatin, fluvastatin, pravastatin, and simvastatin on endothelial function, lipid peroxidation, and aortic atherosclerosis in hypercholesterolemic rabbits]. | Arquivos brasileiros de cardiologia 20050401 |
| Effect of anticholesterol therapy on soluble ICAM-1 in chronic stroke patients with hyperlipidemia. | The Tokai journal of experimental and clinical medicine 20050401 |
| Electrocardiographic events and cholesterol reduction with pravastatin in patients with hypercholesterolemia: the Hokuriku Lipid Coronary Heart Disease Study-Pravastatin Atherosclerosis Trial. | International journal of cardiology 20050330 |
| Plaque rupture after short periods of fat feeding in the apolipoprotein E-knockout mouse: model characterization and effects of pravastatin treatment. | Circulation 20050322 |
| Not all statins are alike: induced rhabdomyolysis on changing from one statin to another one. | International journal of cardiology 20050310 |
| [Protective effects of pravastatin against atherosclerosis in children with familial hypercholesterolemia]. | Revue medicale suisse 20050302 |
| Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms. | Drug metabolism and disposition: the biological fate of chemicals 20050301 |
| Differential effect of LFA703, pravastatin, and fluvastatin on production of IL-18 and expression of ICAM-1 and CD40 in human monocytes. | Journal of leukocyte biology 20050301 |
| Paradoxical effects of statins on aortic valve myofibroblasts and osteoblasts: implications for end-stage valvular heart disease. | Arteriosclerosis, thrombosis, and vascular biology 20050301 |
| HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301 |
| Effects of statins on vascular function of endothelin-1. | British journal of pharmacology 20050301 |
| Effects of fosinopril and pravastatin on carotid intima-media thickness in subjects with increased albuminuria. | Stroke 20050301 |
| Intensive versus moderate lipid lowering with statins in acute coronary syndromes. | Current atherosclerosis reports 20050301 |
| Reversal of atherosclerosis with aggressive lipid lowering. | Current atherosclerosis reports 20050301 |
| Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis. | Metabolism: clinical and experimental 20050301 |
| Modulation of the inflammatory process by statins. | Timely topics in medicine. Cardiovascular diseases 20050301 |
| Commentary. Additive benefits of pravastatin and aspirin to decrease risks of cardiovascular disease: randomized and observational comparisons of secondary prevention trials and their meta-analyses. | Perspectives in vascular surgery and endovascular therapy 20050301 |
| A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line. | The AAPS journal 20050301 |
| How common is rhabdomyolysis in patients receiving lipid-lowering therapy? | Nature clinical practice. Cardiovascular medicine 20050301 |
| Pravastatin may prevent disease progression in normocholesterolemic people with coronary artery disease. Commentary. | Evidence-based cardiovascular medicine 20050301 |
| By the way, doctor. I take Pravachol to control my cholesterol, and because of high triglycerides, my doctor wants to add TriCor. But my pharmacist warns against taking both medications. If I don't take TriCor, are there alternatives? | Harvard health letter 20050301 |
| [Clinical protocol. Pravastatin for the prevention of the destruction of the nutritional status of hemodialysis patients exhibiting chronic inflammation]. | Nephrologie & therapeutique 20050301 |
| Ongoing clinical trials of the pleiotropic effects of statins. | Vascular health and risk management 20050301 |
| Differential associations between actual and expected GP practice prescribing rates for statins, ACE inhibitors, and beta-blockers: a cross-sectional study in England. | Therapeutics and clinical risk management 20050301 |
| Update of antibiotic trials for secondary prevention of coronary heart disease. | Future cardiology 20050301 |
| Public welfare agenda or corporate research agenda? | Mens sana monographs 20050301 |
| Quantitative determination of pravastatin and R-416, its main metabolite in human plasma, by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225 |
| Relaxant effects of pravastatin, atorvastatin and cerivastatin on isolated rat aortic rings. | Life sciences 20050225 |
| Inhibitory effect of fluvastatin on ileal ulcer formation in rats induced by nonsteroidal antiinflammatory drug. | World journal of gastroenterology 20050221 |
| A prospective trial to evaluate the safety and efficacy of pravastatin for the treatment of refractory chronic graft-versus-host disease. | Transplantation 20050215 |
| Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex. | The Journal of pharmacology and experimental therapeutics 20050201 |
| Long-term effects of statins on arterial pressure and stiffness of hypertensives. | Journal of human hypertension 20050201 |
| Statins as coronary vasodilators in isolated bovine coronary arteries--involvement of PGI2 and NO. | Prostaglandins, leukotrienes, and essential fatty acids 20050201 |
| A literature search on pharmacokinetic drug interactions of statins and analysis of how such interactions are reflected in package inserts in Japan. | Journal of clinical pharmacy and therapeutics 20050201 |
| Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update. | Fundamental & clinical pharmacology 20050201 |
| Effects of rosuvastatin, atorvastatin, simvastatin, and pravastatin on atherogenic dyslipidemia in patients with characteristics of the metabolic syndrome. | The American journal of cardiology 20050201 |
| The influence of guidelines on the use of statins: analysis of prescribing trends 1998-2002. | British journal of clinical pharmacology 20050201 |
| Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level. | Acta physiologica Scandinavica 20050201 |
| Pravastatin modulates early diabetic nephropathy in an experimental model of diabetic renal disease. | The Journal of surgical research 20050201 |
| Rosuvastatin is cost-effective in treating patients to low-density lipoprotein-cholesterol goals compared with atorvastatin, pravastatin and simvastatin: analysis of the STELLAR trial. | European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20050201 |
| The relation between hypoalbuminemia and compliance and intima-media thickness of carotid artery in continuous ambulatory peritoneal dialysis patients. | Journal of Korean medical science 20050201 |
| Cost-efficacy analysis of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors based on results of the STELLAR trial: clinical implications for therapeutic selection. | Pharmacotherapy 20050201 |
| Characterization of secretory intestinal transport of phenolsulfonphthalein. | Drug metabolism and pharmacokinetics 20050201 |
| Effects of switching pravastatin to cerivastatin on C-reactive protein, butyrylcholinesterase, and lipids. | Current medical research and opinion 20050201 |
| [Effects of interaction between vascular endothelial cells and monocytes on expression of matrix metalloproteinase-2 and of tissue inhibitor of metalloproteinases 2 and regulation of pravastatin]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20050201 |
| Effect of statins on LDL particle size in patients with familial combined hyperlipidemia: a comparison between atorvastatin and pravastatin. | Nutrition, metabolism, and cardiovascular diseases : NMCD 20050201 |
| Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects. | Circulation 20050125 |
| C-reactive protein levels and outcomes after statin therapy. | The New England journal of medicine 20050106 |
| Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. | The New England journal of medicine 20050106 |
| Effects of combined estriol/pravastatin therapy on intima-media thickness of common carotid artery in hyperlipidemic postmenopausal women. | Gynecologic and obstetric investigation 20050101 |
| Inhibitory effects of mevastatin and a geranylgeranyl transferase I inhibitor (GGTI-2166) on mononuclear osteoclast formation induced by receptor activator of NF kappa B ligand (RANKL) or tumor necrosis factor-alpha (TNF-alpha). | Biochemical pharmacology 20050101 |
| Pravastatin therapy is associated with reduction in coronary allograft vasculopathy in pediatric heart transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050101 |
| Effect of pravastatin on impaired endothelium-dependent relaxation induced by lysophosphatidylcholine in rat aorta. | Acta pharmacologica Sinica 20050101 |
| Are Canadian guidelines for cholesterol lowering in high-risk patients optimal? | The Canadian journal of cardiology 20050101 |
| Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS. | Lipids in health and disease 20050101 |
| Review of efficacy of rosuvastatin 5 mg. | International journal of clinical practice 20050101 |
| PROVE IT then believe it. | International journal of clinical practice 20050101 |
| Preventing type 2 diabetes mellitus. | The Journal of the American Board of Family Practice 20050101 |
| A comparative crossover study of the effects of fluvastatin and pravastatin (FP-COS) on circulating autoantibodies to oxidized LDL in patients with hypercholesterolemia. | Journal of atherosclerosis and thrombosis 20050101 |
| Risk evaluation of coronary heart disease and cerebrovascular disease by the Japan Atherosclerosis Society Guidelines 2002 using the cohort of the Holicos-PAT study. | Journal of atherosclerosis and thrombosis 20050101 |
| Prevalence of potentially severe drug-drug interactions in ambulatory patients with dyslipidaemia receiving HMG-CoA reductase inhibitor therapy. | Drug safety 20050101 |
| Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases? | Arthritis research & therapy 20050101 |
| The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomised placebo-controlled trial [ISRCTN48489393]. | BMC medicine 20050101 |
| Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report. | Critical care (London, England) 20050101 |
| Mevastatin induces apoptosis in HL60 cells dependently on decrease in phosphorylated ERK. | Molecular and cellular biochemistry 20050101 |
| The 'Statinth' wonder of the world: a panacea for all illnesses or a bubble about to burst. | Journal of negative results in biomedicine 20050101 |
| A pharmacoeconomic evaluation of statins in the treatment of hypercholesterolaemia in the primary care setting in Spain. | PharmacoEconomics 20050101 |
| Adverse events with concomitant amiodarone and statin therapy. | Preventive cardiology 20050101 |
| Ezetimibe: a review of its metabolism, pharmacokinetics and drug interactions. | Clinical pharmacokinetics 20050101 |
| Effect of rosuvastatin on outcomes in chronic haemodialysis patients - design and rationale of the AURORA study. | Current controlled trials in cardiovascular medicine 20050101 |
| Acute myopathy in a patient with concomitant use of pravastatin and colchicine. | The Annals of pharmacotherapy 20050101 |
| Herb-drug interactions: a literature review. | Drugs 20050101 |
| [Clinical study of pravastatin with different dosage in early admission period in patients with unstable angina]. | Zhonghua xin xue guan bing za zhi 20050101 |
| Chlamydophila pneumoniae induces expression of toll-like receptor 4 and release of TNF-alpha and MIP-2 via an NF-kappaB pathway in rat type II pneumocytes. | Respiratory research 20050101 |
| Comparison of rosuvastatin and atorvastatin for lipid lowering in patients with type 2 diabetes mellitus: results from the URANUS study. | Cardiovascular diabetology 20050101 |
| Statins research unfinished saga: desirability versus feasibility. | Cardiovascular diabetology 20050101 |
| A cluster randomized trial to assess the impact of opinion leader endorsed evidence summaries on improving quality of prescribing for patients with chronic cardiovascular disease: rationale and design [ISRCTN26365328]. | BMC cardiovascular disorders 20050101 |
| Association of CETP TaqI and APOE polymorphisms with type II diabetes mellitus in North Indians: a case control study. | BMC endocrine disorders 20050101 |
| Stimulatory effects of statins on bone marrow-derived mesenchymal stem cells. Study of a new therapeutic agent for fracture. | Bio-medical materials and engineering 20050101 |
| Medication adherence trends with statins. | Advances in therapy 20050101 |
| HMG-CoA reductase inhibitors suppress the development and progression of carotid artery intimal-medial thickening in hypercholesterolemic type 2 diabetic patients. | Journal of atherosclerosis and thrombosis 20050101 |
| Pitavastatin enhanced lipoprotein lipase expression in 3T3-L1 preadipocytes. | Journal of atherosclerosis and thrombosis 20050101 |
| The effect of prior statin use on 30-day mortality for patients hospitalized with community-acquired pneumonia. | Respiratory research 20050101 |
| Changes in serum levels of E-selectin correlate to improved glycaemic control and reduced obesity in subjects with the metabolic syndrome. | Scandinavian journal of clinical and laboratory investigation 20050101 |
| The non-invasive documentation of coronary microcirculation impairment: role of transthoracic echocardiography. | Cardiovascular ultrasound 20050101 |
| An association study of 43 SNPs in 16 candidate genes with atorvastatin response. | The pharmacogenomics journal 20050101 |
| Expression and subcellular localization of aquaporin water channels in the polarized hepatocyte cell line, WIF-B. | BMC physiology 20050101 |
| Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]. | Cardiovascular diabetology 20050101 |
| [Isoprenoid pigments in representatives of the family Microbacteriaceae]. | Mikrobiologiia 20050101 |
| [Severe muscle disorders associated with statins: analysis of cases notified in France up to the end of February 2002 and data concerning the risk profile of cerivastatin]. | Therapie 20050101 |
| Statins and LDL-cholesterol lowering: an overview. | Current medical research and opinion 20050101 |
| JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs. | BMC cardiovascular disorders 20050101 |
| The clopidogrel after surgery for coronary artery disease (CASCADE) randomized controlled trial: clopidogrel and aspirin versus aspirin alone after coronary bypass surgery [NCT00228423]. | Current controlled trials in cardiovascular medicine 20050101 |
| Considerations in the treatment of dyslipidemia associated with chronic kidney failure and renal transplantation. | Preventive cardiology 20050101 |
| Treatment of dyslipidemia with lovastatin and ezetimibe in an adolescent with cholesterol ester storage disease. | Lipids in health and disease 20050101 |
| Unblinding of trial participants to their treatment allocation: lessons from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). | Clinical trials (London, England) 20050101 |
| Cost-effectiveness of rosuvastatin compared with other statins from a managed care perspective. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20050101 |
| Inhibitory effect of pravastatin on transforming growth factor beta1-inducible gene h3 expression in a rat model of chronic cyclosporine nephropathy. | American journal of nephrology 20050101 |
| Lipids and stroke: the opportunity of lipid-lowering treatment. | Cerebrovascular diseases (Basel, Switzerland) 20050101 |
| Quality of life after acute myocardial infarction: a comparison of diabetic versus non-diabetic acute myocardial infarction patients in Quebec acute care hospitals. | Health and quality of life outcomes 20050101 |
| [Effect of n-3 polyunsaturated fatty acids on plasma lipid, LDL lipoperoxidation, homocysteine and inflammation indicators in diabetic dyslipidemia treated with statin + fibrate combination]. | Casopis lekaru ceskych 20050101 |
| Isolation of a cDNA encoding the alpha-subunit of CAAX-prenyltransferases from Catharanthus roseus and the expression of the active recombinant protein farnesyltransferase. | Cellular & molecular biology letters 20050101 |
| [Hypertension combined with atherosclerotic lesions in carotid arteries: should angiotensin converting enzyme inhibitors be prescribed?]. | Kardiologiia 20050101 |
| Pravastatin improves insulin resistance in dyslipidemic patients. | Journal of atherosclerosis and thrombosis 20050101 |
| The status of lipid management in 1,836 patients with coronary artery disease: a multicenter survey to evaluate the percentage of Japanese coronary artery disease patients achieving the target low-density lipoprotein cholesterol level specified by the Japan Atherosclerosis Society. | Journal of atherosclerosis and thrombosis 20050101 |
| Comparison of the effects of D-003, a mixture of high-molecular-weight aliphatic acids from sugarcane wax, and pravastatin on bones and osteoclast apoptosis of ovariectomized rats. | Drugs under experimental and clinical research 20050101 |
| HMG-CoA reductase inhibitors reduce matrix metalloproteinase-9 activity in human varicose veins. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20050101 |
| [Evaluation of thrombin generation and clot bound thrombin in plasma of hyperlipidemic patients treated with statins]. | Przeglad lekarski 20050101 |
| [Statins in patients with renal failure--the current therapeutic status]. | Przeglad lekarski 20050101 |
| The University of California at Los Angeles heart transplantation experience. | Clinical transplants 20050101 |
| Successful Treatment with Colesevelam HCl and Pravastatin in a Patient Previously Hospitalised with Severe Normal CPK Myopathy on Introduction of Simvastatin. | Clinical drug investigation 20050101 |
| Aliskiren in hypertension: evidence for its potential therapeutic value. | Core evidence 20050101 |
| Chronic cyclosporine nephrotoxicity: new insights and preventive strategies. | Yonsei medical journal 20041231 |
| Mechanistic and epidemiologic considerations in the evaluation of adverse birth outcomes following gestational exposure to statins. | American journal of medical genetics. Part A 20041215 |
| Statin-associated exacerbation of myasthenia gravis. | Neurology 20041214 |
| HMG-CoA reductase inhibitors induce COX-2 gene expression in murine macrophages: role of MAPK cascades and promoter elements for CREB and C/EBPbeta. | Experimental cell research 20041210 |
| Involvement of multiple transporters in the efflux of 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors across the blood-brain barrier. | The Journal of pharmacology and experimental therapeutics 20041201 |
| [Statin therapy in patients with acute coronary syndrome. 'Prove-it' study]. | Der Internist 20041201 |
| Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS--a randomized double-blind trial. | Stroke 20041201 |
| Statins inhibit synthesis of an oxysterol ligand for the liver x receptor in human macrophages with consequences for cholesterol flux. | Arteriosclerosis, thrombosis, and vascular biology 20041201 |
| Pharmacogenetic study of statin therapy in cholesterol reduction. | Current hypertension reports 20041201 |
| Intensive statin therapy in acute coronary syndromes: clinical benefits and vascular biology. | Current opinion in lipidology 20041201 |
| Therapy and clinical trials: clinical therapy and trials. | Current opinion in lipidology 20041201 |
| Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs. | JAMA 20041201 |
| Hypolipidemic drugs can change the composition of rat brain lipids. | The Tohoku journal of experimental medicine 20041201 |
| Effects of a statin group drug, pravastatin, on the insulin resistance in patients with metabolic syndrome. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20041201 |
| Effect of aggressive versus moderate lipid-lowering therapy on myocardial ischemia: the rationale, design, and baseline characteristics of the Study Assessing Goals in the Elderly (SAGE). | American heart journal 20041201 |
| Consistency in efficacy and safety of ezetimibe coadministered with statins for treatment of hypercholesterolemia in women and men. | Journal of women's health (2002) 20041201 |
| A novel variant allele of OATP-C (SLCO1B1) found in a Japanese patient with pravastatin-induced myopathy. | Drug metabolism and pharmacokinetics 20041201 |
| What did PROVE-IT prove? | Diabetes technology & therapeutics 20041201 |
| Multiple antiplatelet effects of clopidogrel are not modulated by statin type in patients undergoing percutaneous coronary intervention. | Platelets 20041201 |
| Trial finds administering pravastatin early after symptom onset does not improve outcomes in people with acute coronary syndromes. | Evidence-based cardiovascular medicine 20041201 |
| Fluvastatin and lovastatin but not pravastatin induce neuroglial differentiation in human mesenchymal stem cells. | Journal of cellular biochemistry 20041115 |
| Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia. | The Journal of biological chemistry 20041112 |
| Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells. | Circulation 20041109 |
| Effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria. | Circulation 20041102 |
| Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Disorder resembling Guillain-Barré syndrome on initiation of statin therapy. | Muscle & nerve 20041101 |
| Statin therapy in kidney disease populations: potential benefits beyond lipid lowering and the need for clinical trials. | Current opinion in nephrology and hypertension 20041101 |
| Framingham score and microalbuminuria: combined future targets for primary prevention? | Kidney international. Supplement 20041101 |
| Elevated soluble tumor necrosis factor receptor levels in non-obese adults with the atherogenic dyslipoproteinemia. | Atherosclerosis 20041101 |
| Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atorvastatin when coadministered with cytochrome P450 inhibitors. | The American journal of cardiology 20041101 |
| Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C). | Pharmacogenetics 20041101 |
| Statins: can the new generation make an impression? | Expert opinion on emerging drugs 20041101 |
| Tracking regression and progression of atherosclerosis in human carotid arteries using high-resolution magnetic resonance imaging. | Magnetic resonance imaging 20041101 |
| Effects of statins on circulating oxidized low-density lipoprotein in patients with hypercholesterolemia. | Japanese heart journal 20041101 |
| Can pravastatin lower coronary event rate if HDL and LDL cholesterol are at low levels? | Nature clinical practice. Cardiovascular medicine 20041101 |
| Optimal windows of statin use for immediate infarct limitation: 5'-nucleotidase as another downstream molecule of phosphatidylinositol 3-kinase. | Circulation 20041012 |
| Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil. | The Journal of pharmacology and experimental therapeutics 20041001 |
| Effects of pravastatin on the expression of ATP-binding cassette transporter A1. | The Journal of pharmacology and experimental therapeutics 20041001 |
| Randomized, controlled trial of secondary prevention of coronary sclerosis in normocholesterolemic patients using pravastatin: final 5-year angiographic follow-up of the Prevention of Coronary Sclerosis (PCS) study. | International journal of cardiology 20041001 |
| An approach to the residence time distribution for stochastic multi-compartment models. | Mathematical biosciences 20041001 |
| Effect of pravastatin on left ventricular mass by activation of myocardial K ATP channels in hypercholesterolemic rabbits. | Atherosclerosis 20041001 |
| Safety of rosuvastatin. | The American journal of cardiology 20041001 |
| [Endothelial dysfunction, inflammation and statins: new evidences]. | Revista espanola de cardiologia 20041001 |
| [Effect of the early administration of pravastatin on C-reactive protein and interleukin-6 levels in the acute phase of myocardial infarction with ST segment elevation]. | Revista espanola de cardiologia 20041001 |
| Mevastatin inhibits ovarian theca-interstitial cell proliferation and steroidogenesis. | Fertility and sterility 20041001 |
| Genistein supplementation inhibits atherosclerosis with stabilization of the lesions in hypercholesterolemic rabbits. | Journal of Korean medical science 20041001 |
| Ezetimibe: new preparation. A cholesterol-lowering drug with no clinical advantage. | Prescrire international 20041001 |
| Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1. | PLoS medicine 20041001 |
| Therapeutic effects of ml-236B in primary hypercholesterolemia. 1980. | Atherosclerosis. Supplements 20041001 |
| Effects of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase on serum lipoproteins and ubiquinone-10 levels in patients with familial hypercholesterolemia. 1981. | Atherosclerosis. Supplements 20041001 |
| Lowering plasma cholesterol by raising ldl receptors. 1981. | Atherosclerosis. Supplements 20041001 |
| Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholeserolemia heterozygotes. 1983. | Atherosclerosis. Supplements 20041001 |
| Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. 1995. | Atherosclerosis. Supplements 20041001 |
| Guidelines for lowering lipids to reduce coronary artery disease risk: a comparison of rosuvastatin with atorvastatin, pravastatin, and simvastatin for achieving lipid-lowering goals. 2003. | Atherosclerosis. Supplements 20041001 |
| Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain. | Neurochemical research 20041001 |
| Eisai hyperbilirubinemic rat (EHBR) as an animal model affording high drug-exposure in toxicity studies on organic anions. | Drug metabolism and pharmacokinetics 20041001 |
| Biliary excretion of bile acids and organic anions in rats with dichloroethylene-induced bile canalicular injury. | Journal of gastroenterology 20041001 |
| How low should your cholesterol go? Even lower may be better. For those at highest risk, very low cholesterol levels may help prevent a second heart attack or stroke. | Health news (Waltham, Mass.) 20041001 |
| Effect of pravastatin on cardiovascular events in people with chronic kidney disease. | Circulation 20040921 |
| Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells. | Blood 20040915 |
| Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20040903 |
| [Lowering of cholesterol. What role is played by the choice of statins?]. | MMW Fortschritte der Medizin 20040902 |
| An integrated evaluation of endothelial constitutive nitric oxide synthase polymorphisms and coronary artery disease in men. | Clinical science (London, England : 1979) 20040901 |
| Effects of Dai-saiko-to (Da-Chai-Hu-Tang) on plasma lipids and atherosclerotic lesions in female heterozygous heritable Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. | Pharmacological research 20040901 |
| Early effect of pravastatin on serum soluble CD40L, matrix metalloproteinase-9, and C-reactive protein in patients with acute myocardial infarction. | Clinical chemistry 20040901 |
| Low-density lipoprotein reduction in high-risk patients: how low do you go? | Current atherosclerosis reports 20040901 |
| Lessons learned from the prospective pravastatin pooling project. | Current atherosclerosis reports 20040901 |
| ALLHAT-LLT: questions, questions, and more questions (and some answers). | Current atherosclerosis reports 20040901 |
| HMG-CoA reductase inhibitors and the risk of vertebral fracture. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040901 |
| Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance associated protein 2. | Molecular pharmacology 20040901 |
| Statins and newly diagnosed diabetes. | British journal of clinical pharmacology 20040901 |
| Is decreased libido associated with the use of HMG-CoA-reductase inhibitors? | British journal of clinical pharmacology 20040901 |
| Design and baseline characteristics of a study of primary prevention of coronary events with pravastatin among Japanese with mildly elevated cholesterol levels. | Circulation journal : official journal of the Japanese Circulation Society 20040901 |
| Atorvastatin versus pravastatin: intensive versus moderate lipid lowering. | Expert opinion on pharmacotherapy 20040901 |
| Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells. | Journal of the American Society of Nephrology : JASN 20040901 |
| Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3beta and transcription factor beta-catenin. | Journal of molecular and cellular cardiology 20040901 |
| Oral administration of pravastatin reduces egg cholesterol but not plasma cholesterol in laying hens. | Poultry science 20040901 |
| New decalin derivatives, eujavanoic acids A and B, from Eupenicillium javanicum. | Journal of natural products 20040901 |
| Rosuvastatin in the management of hyperlipidemia. | Clinical therapeutics 20040901 |
| Effects of rosuvastatin versus atorvastatin, simvastatin, and pravastatin on non-high-density lipoprotein cholesterol, apolipoproteins, and lipid ratios in patients with hypercholesterolemia: additional results from the STELLAR trial. | Clinical therapeutics 20040901 |
| Antiinflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation. | Circulation 20040831 |
| Pitavastatin increases ABCA1-mediated lipid efflux from Fu5AH rat hepatoma cells. | Biochemical and biophysical research communications 20040827 |
| Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways. | Circulation research 20040820 |
| Effects of pravastatin on progression of glucose intolerance and cardiovascular remodeling in a type II diabetes model. | Journal of the American College of Cardiology 20040818 |
| Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins. | Circulation 20040817 |
| HMG-CoA reductase inhibitors for lowering elevated levels of C-reactive protein. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040815 |
| Intensive versus moderate lipid lowering with statins after acute coronary syndromes. | The New England journal of medicine 20040812 |
| Intensive versus moderate lipid lowering with statins after acute coronary syndromes. | The New England journal of medicine 20040812 |
| Intensive versus moderate lipid lowering with statins after acute coronary syndromes. | The New England journal of medicine 20040812 |
| Intensive versus moderate lipid lowering with statins after acute coronary syndromes. | The New England journal of medicine 20040812 |
| Intensive versus moderate lipid lowering with statins after acute coronary syndromes. | The New England journal of medicine 20040812 |
| Updated guidelines support even lower cholesterol levels for at-risk patients. | Report on medical guidelines & outcomes research 20040806 |
| [Patient feels completely well. The PROCAM Score first reveals the high infarct risk]. | MMW Fortschritte der Medizin 20040805 |
| Tamoxifen treatment reverses the adverse effects of chemotherapy-induced ovarian failure on serum lipids. | British journal of cancer 20040802 |
| Treatment of type IIb familial combined hyperlipidemia with the combination pravastatin-piperazine sultosilate. | European journal of pharmacology 20040802 |
| Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors. | American journal of physiology. Heart and circulatory physiology 20040801 |
| Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice. | American journal of physiology. Regulatory, integrative and comparative physiology 20040801 |
| Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
| Cholesterol-lowering independent regression and stabilization of atherosclerotic lesions by pravastatin and by antimonocyte chemoattractant protein-1 therapy in nonhuman primates. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
| Interleukin-6, fibrin D-dimer, and coagulation factors VII and XIIa in prediction of coronary heart disease. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
| Effects of pravastatin and bezafibrate on biliary lipid excretion and hepatic expression of Abcg5 and Abcg8 in the rat. | Journal of gastroenterology and hepatology 20040801 |
| CETP gene variation: relation to lipid parameters and cardiovascular risk. | Current opinion in lipidology 20040801 |
| Statin therapy in the elderly. | Current opinion in lipidology 20040801 |
| AT-1 receptor blockade prevents proteinuria, renal failure, hyperlipidemia, and glomerulosclerosis in the Imai rat. | Kidney international 20040801 |
| Different effects of pravastatin and cerivastatin on the media of the carotid arteries as assessed by integrated backscatter ultrasound. | Circulation journal : official journal of the Japanese Circulation Society 20040801 |
| Lipid-lowering response to statins is affected by CYP3A5 polymorphism. | Pharmacogenetics 20040801 |
| Lipid lowering therapy with fluvastatin and pravastatin in patients with HIV infection and antiretroviral therapy: comparison of efficacy and interaction with indinavir. | Infection 20040801 |
| Treatment of hyperlipidemia in cardiac transplant recipients. | American heart journal 20040801 |
| Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia. | International journal of clinical practice 20040801 |
| Lessons from the PROVE-IT trial. Higher dose of potent statin better for high-risk patients. | Cleveland Clinic journal of medicine 20040801 |
| Rosuvastatin: new preparation. Opt for statins with evidence of efficacy on clinical outcome. | Prescrire international 20040801 |
| Lipid rafts mediate the synaptic localization of alpha-synuclein. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040728 |
| Efficacy and safety of statin therapy in children with familial hypercholesterolemia: a randomized controlled trial. | JAMA 20040721 |
| Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis. | Biochemical and biophysical research communications 20040716 |
| [Decreasing LDL level moderately or drastically. Is differential therapy with statins available? (interview by Dirk Einecke)]. | MMW Fortschritte der Medizin 20040708 |
| Effect of pravastatin on low-density lipoprotein oxidation and myocardial perfusion in young adults with type 1 diabetes. | Arteriosclerosis, thrombosis, and vascular biology 20040701 |
| Understanding why older people participate in clinical trials: the experience of the Scottish PROSPER participants. | Age and ageing 20040701 |
| Moderate versus aggressive lipid lowering with statins following an acute coronary syndrome: the pravastatin or atorvastatin evaluation and infection therapy trial. | Current cardiology reports 20040701 |
| 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest. | Anti-cancer drugs 20040701 |
| Effect of pravastatin compared with placebo initiated within 24 hours of onset of acute myocardial infarction or unstable angina: the Pravastatin in Acute Coronary Treatment (PACT) trial. | American heart journal 20040701 |
| Comparison of levels of matrix metalloproteinases, tissue inhibitor of metalloproteinases, interleukins, and tissue necrosis factor in carotid endarterectomy specimens from patients on versus not on statins preoperatively. | The American journal of cardiology 20040701 |
| High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1). | Pharmacogenetics 20040701 |
| New LDL goals: even lower? | The Johns Hopkins medical letter health after 50 20040701 |
| [Pharmacoeconomic analysis of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor therapy for the secondary prevention of coronary heart disease]. | Nihon eiseigaku zasshi. Japanese journal of hygiene 20040701 |
| Pharmacogenetic study of statin therapy and cholesterol reduction. | JAMA 20040616 |
| Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors. | Biochemical pharmacology 20040615 |
| Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier. | The Journal of pharmacology and experimental therapeutics 20040601 |
| Compactin-a review. | Applied microbiology and biotechnology 20040601 |
| Rhabdomyolysis in association with simvastatin and amiodarone. | The Annals of pharmacotherapy 20040601 |
| Novel cardioprotective effects of pravastatin in human ventricular cardiomyocytes subjected to hypoxia and reoxygenation: beneficial effects of statins independent of endothelial cells. | The Journal of surgical research 20040601 |
| Effect of pravastatin on myocardial perfusion after percutaneous transluminal coronary angioplasty. | The American journal of cardiology 20040601 |
| Therapy for unresectable hepatocellular carcinoma: review of the randomized clinical trials-II: systemic and local non-embolization-based therapies in unresectable and advanced hepatocellular carcinoma. | Anti-cancer drugs 20040601 |
| Intensive lipid-lowering therapy in coronary artery disease: implications of the REVERSAL and PROVE-IT trials. | Expert opinion on investigational drugs 20040601 |
| Pravastatin has an additional depressor effect in patients undergoing long-term treatment with antihypertensive drugs. | American journal of hypertension 20040601 |
| Statins: novel additions to the dermatologic arsenal? | Experimental dermatology 20040601 |
| High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs. | Steroids 20040601 |
| [In vitro effects of mevastatin on the proliferation and apoptosis in human multiple myeloma cell line U266]. | Zhongguo shi yan xue ye xue za zhi 20040601 |
| The importance of aggressive lipid management in patients at risk: evidence from recent clinical trials. | Clinical cardiology 20040601 |
| Metaanalysis of statins and survival in de novo cardiac transplantation. | Transplantation proceedings 20040601 |
| Pharmacokinetic interactions of drugs with St John's wort. | Journal of psychopharmacology (Oxford, England) 20040601 |
| Molecular basis of ML-236B production in the high-producing mutant No. 41520 of Penicillium citrinum. | The Journal of general and applied microbiology 20040601 |
| Clopidogrel-atorvastatin interaction. | Circulation 20040525 |
| Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, reduces delayed neuronal death following transient forebrain ischemia in the adult rat hippocampus. | Neuroscience letters 20040520 |
| The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease. | Circulation 20040518 |
| Meta-analysis of large randomized controlled trials to evaluate the impact of statins on cardiovascular outcomes. | British journal of clinical pharmacology 20040501 |
| HMG CoA reductase inhibitors and the risk of venous thrombosis among postmenopausal women. | Journal of thrombosis and haemostasis : JTH 20040501 |
| Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes. | Molecular pharmacology 20040501 |
| Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics. | Clinical pharmacology and therapeutics 20040501 |
| The effect of gemfibrozil on the pharmacokinetics of rosuvastatin. | Clinical pharmacology and therapeutics 20040501 |
| Pharmacogenetics of the CD14 endotoxin receptor polymorphism and progression of coronary atherosclerosis. | Thrombosis and haemostasis 20040501 |
| Treating low HDL-cholesterol in normocholesterolaemic patients with coronary disease: statins, fibrates or horses for courses? | European heart journal 20040501 |
| Effects of pravastatin on coronary events in 2073 patients with low levels of both low-density lipoprotein cholesterol and high-density lipoprotein cholesterol: results from the LIPID study. | European heart journal 20040501 |
| Effects of a novel antihyperlipidemic agent, S-2E, on the blood lipid abnormalities in homozygous WHHL rabbits. | Metabolism: clinical and experimental 20040501 |
| Lipitor bests Pravachol at certain doses. | Health news (Waltham, Mass.) 20040501 |
| Pravastatin in patients with nonalcoholic steatohepatitis: results of a pilot study. | Atherosclerosis 20040501 |
| Cholesterol: low is good. Lower is better. PROVE IT has doctors rethinking how to treat high cholesterol and what's a good target. | Harvard heart letter : from Harvard Medical School 20040501 |
| Cholesterol limbo: How low should the bar go. Ratcheting down LDL to extra-low levels with high-dose statins seems to work wonders. | Harvard health letter 20040501 |
| Statins and liver toxicity: a meta-analysis. | Pharmacotherapy 20040501 |
| Bioequivalence of pravastatin tablet formulations assessed in Korean males. | International journal of clinical pharmacology and therapeutics 20040501 |
| [The Prosper-Study: practical consequences?]. | Der Internist 20040501 |
| 'Major surprise' in a new study means likely changes in treatment. | Heart advisor 20040501 |
| [Comparison of effects of taizhi' an capsule and pravastatin on vascular endothelial function in senile patients with coronary heart disease]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040501 |
| Intensive versus moderate lipid lowering with statins after acute coronary syndromes. | The New England journal of medicine 20040408 |
| Intensive statin therapy--a sea change in cardiovascular prevention. | The New England journal of medicine 20040408 |
| HMG-CoA reductase inhibitor attenuates platelet adhesion in intestinal venules of hypercholesterolemic mice. | American journal of physiology. Heart and circulatory physiology 20040401 |
| Hydroxy-methylglutaryl-coenzyme A reductase inhibition improves endothelial dysfunction in type-1 diabetes. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20040401 |
| The UCSD Statin Study: a randomized controlled trial assessing the impact of statins on selected noncardiac outcomes. | Controlled clinical trials 20040401 |
| Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese. | British journal of clinical pharmacology 20040401 |
| Professional athletes suffering from familial hypercholesterolaemia rarely tolerate statin treatment because of muscular problems. | British journal of clinical pharmacology 20040401 |
| Plasma clearance of human low-density lipoprotein in human apolipoprotein B transgenic mice is related to particle diameter. | Metabolism: clinical and experimental 20040401 |
| Preventing type II diabetes mellitus. | Journal of clinical pharmacology 20040401 |
| Effects of pravastatin on lipoproteins and endothelial function in patients receiving human immunodeficiency virus protease inhibitors. | American heart journal 20040401 |
| Effects of switching statins on achievement of lipid goals: Measuring Effective Reductions in Cholesterol Using Rosuvastatin Therapy (MERCURY I) study. | American heart journal 20040401 |
| Impaired myocardial vasodilatation during hyperaemic stress is improved by simvastatin but not by pravastatin in patients with hypercholesterolaemia. | European heart journal 20040401 |
| Pharmacokinetics of flunixin in the cat: enterohepatic circulation and active transport mechanism in the liver. | Journal of veterinary pharmacology and therapeutics 20040401 |
| American Heart Association scientific sessions. | Expert opinion on investigational drugs 20040401 |
| Statins and secondary prevention of coronary heart disease. | British journal of community nursing 20040401 |
| Believe-it then PROVE-IT. | International journal of clinical practice 20040401 |
| [Lower, lower, lower. The LDL goal value of 200 mg/dl is still much too high]. | MMW Fortschritte der Medizin 20040325 |
| [Results of randomized study: intensive lipid lowering treatment stops coronary atherosclerosis]. | MMW Fortschritte der Medizin 20040325 |
| [Regarding LDL cholesterol: the lower, the better (interview by Dr. Dirk Einecke)]. | MMW Fortschritte der Medizin 20040325 |
| Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes. | Circulation 20040323 |
| Regulation of geranylgeranyl pyrophosphate synthase in the proliferation of rat FRTL-5 cells: involvement of both cAMP-PKA and PI3-AKT pathways. | Biochemical and biophysical research communications 20040319 |
| Analysis of pravastatin to prevent recurrence of atrial fibrillation after electrical cardioversion. | The American journal of cardiology 20040315 |
| Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling. | Biochemical and biophysical research communications 20040312 |
| Chronic exposure to U18666A induces apoptosis in cultured murine cortical neurons. | Biochemical and biophysical research communications 20040305 |
| Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. | JAMA 20040303 |
| High-intensity statin treatment for coronary heart disease. | JAMA 20040303 |
| The cholesteryl ester transfer protein (CETP) TaqIB polymorphism in the cholesterol and recurrent events study: no interaction with the response to pravastatin therapy and no effects on cardiovascular outcome: a prospective analysis of the CETP TaqIB polymorphism on cardiovascular outcome and interaction with cholesterol-lowering therapy. | Journal of the American College of Cardiology 20040303 |
| Effects of brassinazole, an inhibitor of brassinosteroid biosynthesis, on light- and dark-grown Chlorella vulgaris. | Planta 20040301 |
| Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism. | Arteriosclerosis, thrombosis, and vascular biology 20040301 |
| Haemochromatosis gene mutations and risk of coronary heart disease: a west of Scotland coronary prevention study (WOSCOPS) substudy. | Heart (British Cardiac Society) 20040301 |
| De novo biosynthesis and radiolabeling of mammalian digitalis-like factors. | Clinical chemistry 20040301 |
| Determination of pravastatin in tablets by capillary electrophoresis. | Farmaco (Societa chimica italiana : 1989) 20040301 |
| Hypercholesterolemia is common after pediatric heart transplantation: initial experience with pravastatin. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040301 |
| [Effects of angiotensin II receptor blockers, angiotensin converting enzyme inhibitors, 3-hydroxy-3-methyl glutaryl (HMG) CoA reductase inhibitors, amlodipine and epalrestat on cultured basilar artery smooth muscle cell proliferation]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040301 |
| Association of dyslipidemia and effects of statins on nonmacrovascular diseases. | Clinical therapeutics 20040301 |
| [Clinical study of the month. REVERAL and PROVE-IT: confirmation of the concept ' the lower, the better' for cholesterol therapy in patients with coronary heart disease]. | Revue medicale de Liege 20040301 |
| A boy with autosomal recessive hypercholesterolaemia. | The Netherlands journal of medicine 20040301 |
| [Interactions of statins with antithrombotic drugs]. | Medizinische Klinik (Munich, Germany : 1983) 20040215 |
| Pravastatin up-regulates transforming growth factor-beta1 in THP-1 human macrophages: effect on scavenger receptor class A expression. | Biochemical and biophysical research communications 20040213 |
| Synthesis and biological activity of a novel squalene epoxidase inhibitor, FR194738. | Bioorganic & medicinal chemistry letters 20040209 |
| Statin use and cancer risk in the General Practice Research Database. | British journal of cancer 20040209 |
| Statins reduce oxidized low-density lipoprotein levels, but do not alter soluble intercellular cell-adhesion molecule-1 and vascular cell-adhesion molecule-1 levels in subjects with hypercholesterolaemia. | Clinical science (London, England : 1979) 20040201 |
| Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human. | The Journal of pharmacology and experimental therapeutics 20040201 |
| More Western hypercholesterolemic patients achieve Japan Atherosclerosis Society LDL-C goals with rosuvastatin therapy than with atorvastatin, pravastatin, or simvastatin therapy. | Circulation journal : official journal of the Japanese Circulation Society 20040201 |
| Statins induce the regression of left ventricular mass in patients with angina. | Circulation journal : official journal of the Japanese Circulation Society 20040201 |
| Anti-inflammatory and anticoagulant effects of pravastatin in patients with type 2 diabetes. | Diabetes care 20040201 |
| Acute and chronic regulation of thick ascending limb endothelial nitric oxide synthase by statins. | Journal of the American Society of Nephrology : JASN 20040201 |
| Effect of rifampicin on pravastatin pharmacokinetics in healthy subjects. | British journal of clinical pharmacology 20040201 |
| [Role of lipid lowering therapy in patients with peripheral arterial occlusive disease]. | Herz 20040201 |
| Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine. | Journal of pharmacological sciences 20040201 |
| Clash of the statins? A trial pitting two popular statins against each other helps answer a far more important question: how low should cholesterol go? | Harvard heart letter : from Harvard Medical School 20040201 |
| Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. | European heart journal 20040201 |
| Oral anticoagulant drug interactions with statins: case report of fluvastatin and review of the literature. | Pharmacotherapy 20040201 |
| Diagnostic, clinical, and therapeutic aspects of familial hypercholesterolemia in children. | Seminars in vascular medicine 20040201 |
| Conceptual foundations of the UCSD Statin Study: a randomized controlled trial assessing the impact of statins on cognition, behavior, and biochemistry. | Archives of internal medicine 20040126 |
| Atorvastatin: gold standard for prophylaxis of myocardial ischemia and stroke - comparison of the clinical benefit of statins on the basis of randomized controlled endpoint studies. | European journal of medical research 20040126 |
| Statins potentiate caspase-3 activity in immortalized murine neurons. | Neuroscience letters 20040123 |
| [Treatment with statins of the elderly]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20040122 |
| Effect of physical activity on serum C-reactive protein. | The American journal of cardiology 20040115 |
| Additive benefits of pravastatin and aspirin to decrease risks of cardiovascular disease: randomized and observational comparisons of secondary prevention trials and their meta-analyses. | Archives of internal medicine 20040112 |
| Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors. | European journal of pharmacology 20040112 |
| Lovastatin and mevastatin reduce basal and cytokine-stimulated production of prostaglandins from rat microglial cells in vitro: evidence for a mechanism unrelated to the inhibition of hydroxy-methyl-glutaryl CoA reductase. | Neuroscience letters 20040109 |
| Pravastatin treatment attenuates interstitial inflammation and fibrosis in a rat model of chronic cyclosporine-induced nephropathy. | American journal of physiology. Renal physiology 20040101 |
| Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development. | The Plant cell 20040101 |
| Effect of 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors (statins) on tissue paraoxonase 1 and plasma platelet activating factor acetylhydrolase activities. | Journal of cardiovascular pharmacology 20040101 |
| Characterization of uremic toxin transport by organic anion transporters in the kidney. | Kidney international 20040101 |
| Differential effects of lipid-lowering agents on human cholinesterases. | Clinical biochemistry 20040101 |
| Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular events. | American heart journal 20040101 |
| Comparisons of effects of statins (atorvastatin, fluvastatin, lovastatin, pravastatin, and simvastatin) on fasting and postprandial lipoproteins in patients with coronary heart disease versus control subjects. | The American journal of cardiology 20040101 |
| Does statin therapy influence steroid hormone synthesis? | Zeitschrift fur Kardiologie 20040101 |
| Marked low-density lipoprotein cholesterol reduction below current national cholesterol education program targets provides the greatest reduction in carotid atherosclerosis. | Clinical cardiology 20040101 |
| Pharmacokinetics and pharmacodynamics of pravastatin in pediatric and adolescent cardiac transplant recipients on a regimen of triple immunosuppression. | Clinical pharmacology and therapeutics 20040101 |
| Aggressive lipid-lowering regimen halts CHD progression. | Geriatrics 20040101 |
| Is there a 'best' statin drug? | The Johns Hopkins medical letter health after 50 20040101 |
| Cholesteryl ester transfer protein concentration is associated with progression of atherosclerosis and response to pravastatin in men with coronary artery disease (REGRESS). | European journal of clinical investigation 20040101 |
| A cross-media content analysis of motivational themes in direct-to-consumer prescription drug advertising. | Clinical therapeutics 20040101 |
| Is Lipitor better than Pravachol? | Health news (Waltham, Mass.) 20040101 |
| Prolonged inadvertent pravastatin use in pregnancy. | Reproductive toxicology (Elmsford, N.Y.) 20040101 |
| [Statins-a panacea?]. | Zeitschrift fur Kardiologie 20040101 |
| Down-regulating effect of nicotine on connexin43 gap junctions in human umbilical vein endothelial cells is attenuated by statins. | European journal of cell biology 20040101 |
| Rising statin use and effect on ischemic stroke outcome. | BMC medicine 20040101 |
| Rosuvastatin: a review of its use in the management of dyslipidemia. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101 |
| C-reactive protein is not only an inflammatory marker but also a direct cause of cardiovascular diseases. | Medical hypotheses 20040101 |
| Association between the number of coadministered P-glycoprotein inhibitors and serum digoxin levels in patients on therapeutic drug monitoring. | BMC medicine 20040101 |
| Pravastatin sodium, an inhibitor of HMG-CoA reductase, decreases HDL cholesterol by transfer of cholesteryl ester from HDL to VLDL in Japanese white rabbits. | Journal of atherosclerosis and thrombosis 20040101 |
| Rosuvastatin-induced arrest in progression of renal disease. | Cardiology 20040101 |
| Islet transplantation: an update. | Chang Gung medical journal 20040101 |
| What to do about cholesterol now. Here's the take-home message from startling new research findings. | Heart advisor 20040101 |
| The influence of statins on the free intracellular calcium concentration in human umbilical vein endothelial cells. | BMC cardiovascular disorders 20040101 |
| Comparison of urinary excretion of pravastatin and temocapril in bile duct-ligated rats and Eisai hyperbilirubinemic rats (EHBR). | Journal of hepato-biliary-pancreatic surgery 20040101 |
| Statin therapy in the elderly: observational and randomized controlled trials support event reduction. | The American journal of geriatric cardiology 20040101 |
| A prospective study of pravastatin in the elderly at risk: new hope for older persons. | The American journal of geriatric cardiology 20040101 |
| Positive pleiotropic effects of HMG-CoA reductase inhibitor on vitiligo. | Lipids in health and disease 20040101 |
| Homocysteine and reactive oxygen species in metabolic syndrome, type 2 diabetes mellitus, and atheroscleropathy: the pleiotropic effects of folate supplementation. | Nutrition journal 20040101 |
| Assessing compliance of cardiologists with the national cholesterol education program (NCEP) III guidelines in an ambulatory care setting. | Lipids in health and disease 20040101 |
| Approximate equivalent rosuvastatin doses for temporary statin interchange programs. | The Annals of pharmacotherapy 20040101 |
| [Pravastatin-associated polymyositis, a case report]. | Rinsho shinkeigaku = Clinical neurology 20040101 |
| Statins rise cytoplasmic calcium level [Ca2+]i in cultured endothelial cells. | Polish journal of pharmacology 20040101 |
| Industrial application of fuzzy control in bioprocesses. | Advances in biochemical engineering/biotechnology 20040101 |
| Effect of Nandrolone Decanoate on serum lipoprotein (a) and its isoforms in hemodialysis patients. | Lipids in health and disease 20040101 |
| Pravastatin potentiates the anticoagulant effects of low molecular weight heparin. | Thrombosis research 20040101 |
| Pravastatin reduced major coronary heart disease (CHD) events in patients with abnormal fasting glucose and a history of CHD. | ACP journal club 20040101 |
| Statin drugs do not affect serum complement activation in vitro. | Scandinavian journal of immunology 20040101 |
| Treatment of HCC with pravastatin, octreotide, or gemcitabine--a critical evaluation. | Hepato-gastroenterology 20040101 |
| Aggressive lowering of low-density lipoprotein cholesterol: do the studies apply to the elderly? | The American journal of geriatric cardiology 20040101 |
| Mevastatin-induced apoptosis and growth suppression in U266 myeloma cells. | Anticancer research 20040101 |
| Genetic polymorphisms in cytochrome P450 enzymes: effect on efficacy and tolerability of HMG-CoA reductase inhibitors. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101 |
| Battle of the statins, or how the news media can change patient care. | JAAPA : official journal of the American Academy of Physician Assistants 20040101 |
| [Interactions between foodstuffs and statins]. | Nutricion hospitalaria 20040101 |
| Enhancing effect of dietary cholesterol and inhibitory effect of pravastatin on allergic pulmonary inflammation. | Journal of biomedical science 20040101 |
| Disparities in lipid management for African Americans and Caucasians with coronary artery disease: a national cross-sectional study. | BMC cardiovascular disorders 20040101 |
| [Relationship Between Lipid Lowering and Changes of Hemostasis and Inflammation During Use of Statins in Non-ST Elevation Acute Coronary Syndrome]. | Kardiologiia 20040101 |
| Metabolic cholesterol depletion hinders cell-surface trafficking of the nicotinic acetylcholine receptor. | Neuroscience 20040101 |
| Interactions between grapefruit juice and cardiovascular drugs. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20040101 |
| The pivotal role of cholesterol absorption inhibitors in the management of dyslipidemia. | Lipids in health and disease 20040101 |
| Looking for prognostic information in the ST-T segment--is it really worth it? | Journal of electrocardiology 20040101 |
| The need for a large-scale trial of fibrate therapy in diabetes: the rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. [ISRCTN64783481]. | Cardiovascular diabetology 20040101 |
| Statins: much more than just a lipid-lowering therapy. | Indian heart journal 20040101 |
| Efficacy and safety of coadministration of ezetimibe and statins in elderly patients with primary hypercholesterolaemia. | Drugs & aging 20040101 |
| Atorvastatin and pravastatin elevated pre-heparin lipoprotein lipase mass of type 2 diabetes with hypercholesterolemia. | Journal of atherosclerosis and thrombosis 20040101 |
| [Mevastatin induced apoptosis in U266 human myeloma cell line]. | Magyar onkologia 20040101 |
| KGF-induced motility of breast cancer cells is dependent on Grb2 and Erk1,2. | Clinical & experimental metastasis 20040101 |
| [Effect of eprosartan in combination with pravastatin on some parameters of endothelial function in patients with metabolic syndrome.]. | Kardiologiia 20040101 |
| Closing out a large clinical trial: lessons from the prospective study of pravastatin in the elderly at risk (PROSPER). | Clinical trials (London, England) 20040101 |
| Steady-state pharmacokinetics of pravastatin in children with familial hypercholesterolaemia. | Clinical drug investigation 20040101 |
| [First comparison of 2 statins shows: only radical LDL lowering stops coronary atherosclerosis]. | MMW Fortschritte der Medizin 20031218 |
| Effect of statins on the progression of bioprosthetic aortic valve degeneration. | The American journal of cardiology 20031215 |
| [LDL cholesterol in normal range. The lower the better? Implications of the GREACE study]. | MMW Fortschritte der Medizin 20031211 |
| 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031203 |
| Lipid lowering by pravastatin increases parasympathetic modulation of heart rate: Galpha(i2), a possible molecular marker for parasympathetic responsiveness. | Circulation 20031202 |
| Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20031201 |
| Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade. | American journal of physiology. Renal physiology 20031201 |
| Methyl palmitate: a novel product of the Medfly (Ceratitis capitata) corpus allatum. | Insect biochemistry and molecular biology 20031201 |
| Different effects of simvastatin and pravastatin on adrenal sensitivity to angiotensin II. | British journal of clinical pharmacology 20031201 |
| Perspectives from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial--Lipid Lowering Trial and the Anglo-Scandinavian Cardiac Outcomes Trial--Lipid Lowering Arm. | Current opinion in lipidology 20031201 |
| Antibiotic treatment of atherosclerosis. | Current opinion in lipidology 20031201 |
| Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men. | Journal of internal medicine 20031201 |
| Association of Chlamydia pneumoniae antibody with the cholesterol-lowering effect of statins. | Atherosclerosis 20031201 |
| Effects of atorvastatin and pravastatin on glucose tolerance in diabetic rats mildly induced by streptozotocin. | Biological & pharmaceutical bulletin 20031201 |
| Effects of pravastatin on cardiomyocyte hypertrophy and ventricular vulnerability in normolipidemic rats after myocardial infarction. | Journal of molecular and cellular cardiology 20031201 |
| Direct vascular effects of HR780, a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. | Clinical and experimental pharmacology & physiology 20031201 |
| Pravastatin decreases cold ischemia--but not alloantigen-dependent transplant arteriosclerosis. | Transplantation proceedings 20031201 |
| Accuracy of the Australian National Death Index: comparison with adjudicated fatal outcomes among Australian participants in the Long-term Intervention with Pravastatin in Ischaemic Disease (LIPID) study. | Australian and New Zealand journal of public health 20031201 |
| The next step in cardiovascular protection. | Atherosclerosis. Supplements 20031201 |
| Long-term statin safety and efficacy in secondary prevention: can combination therapy improve outcomes? | Atherosclerosis. Supplements 20031201 |
| Preventing the next event in the elderly: the PROSPER perspective. | Atherosclerosis. Supplements 20031201 |
| [Clinical trials with rosuvastatin: efficacy and safety of its use]. | Italian heart journal : official journal of the Italian Federation of Cardiology 20031201 |
| [Ezetimibe: from pharmacology to clinical trials]. | Annales d'endocrinologie 20031201 |
| Statin face-off. Surprises from the first head-to-head comparison. | Time 20031124 |
| Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia. | British journal of cancer 20031117 |
| Usefulness of lowering low-density lipoprotein cholesterol to <70 mg/dl and usefulness of C-reactive protein in patient selection. | The American journal of cardiology 20031115 |
| Effects of statins on platelet inhibition by a high loading dose of clopidogrel. | Circulation 20031104 |
| Individual difference in the pharmacokinetics of a drug, pravastatin, in healthy subjects. | Journal of clinical pharmacology 20031101 |
| Statin therapy: new therapy for cardiac microvascular dysfunction. | European heart journal 20031101 |
| Benefits of statin treatment in cardiac syndrome-X1. | European heart journal 20031101 |
| Depression and cardiovascular morbidity and mortality: cause or consequence? | European heart journal 20031101 |
| Long-term administration of pravastatin reduces serum lipoprotein(a) levels. | International journal of clinical pharmacology and therapeutics 20031101 |
| Effects of statins on adhesion molecule expression in endothelial cells. | Journal of thrombosis and haemostasis : JTH 20031101 |
| Ca2+-releasing effect of cerivastatin on the sarcoplasmic reticulum of mouse and rat skeletal muscle fibers. | Journal of pharmacological sciences 20031101 |
| [Systemic treatment for hepatocellular carcinoma]. | Zentralblatt fur Chirurgie 20031101 |
| Bioconversion of compactin into pravastatin by Streptomyces sp. | Biotechnology letters 20031101 |
| The cost-effectiveness of a new statin (rosuvastatin) in the UK NHS. | International journal of clinical practice 20031101 |
| Rhabdomyolysis caused by distigmine bromide. | Internal medicine (Tokyo, Japan) 20031101 |
| [Pravastatin for older patients with risk of vascular disease. The PROSPER-Study]. | Der Internist 20031101 |
| Pravastatin reduces the incidence of cardiac events among patients with myocardial infarction. | Japanese heart journal 20031101 |
| Effects of statins on myocardial and coronary artery response to ischemia-reperfusion. | Canadian journal of physiology and pharmacology 20031101 |
| Rosuvastatin: a new inhibitor of HMG-coA reductase for the treatment of dyslipidemia. | Expert review of cardiovascular therapy 20031101 |
| p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases. | The Journal of biological chemistry 20031031 |
| Rapid effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition on coronary endothelial function. | Circulation research 20031031 |
| Pravastatin at 10 mg/day does not decrease plasma levels of either amyloid-beta (Abeta) 40 or Abeta 42 in humans. | Neuroscience letters 20031030 |
| Effect of pravastatin on coronary plaque volume. | The American journal of cardiology 20031015 |
| Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose: results from the LIPID trial. | Diabetes care 20031001 |
| Interleukin-1B genotype modulates the improvement of coronary artery reactivity by lipid-lowering therapy with pravastatin: a placebo-controlled positron emission tomography study in young healthy men. | Pharmacogenetics 20031001 |
| The bisphosphonate pamidronate is a potent inhibitor of Ewing's sarcoma cell growth in vitro. | Anti-cancer drugs 20031001 |
| Pravastatin in hyperlipidemia secondary to HIV protease inhibitors without response to fenofibrate: a brief preliminary report. | Nutrition (Burbank, Los Angeles County, Calif.) 20031001 |
| A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study. | European heart journal 20031001 |
| Effect of pravastatin on LDL particle concentration as determined by NMR spectroscopy: a substudy of a randomized placebo controlled trial. | European heart journal 20031001 |
| Effects of eicosapentaenoic acid on cardiovascular events in Japanese patients with hypercholesterolemia: rationale, design, and baseline characteristics of the Japan EPA Lipid Intervention Study (JELIS). | American heart journal 20031001 |
| Effects of atorvastatin and pravastatin on malondialdehyde-modified LDL in hypercholesterolemic patients. | Circulation journal : official journal of the Japanese Circulation Society 20031001 |
| The mevalonate synthesis pathway as a therapeutic target in cancer. | Clinical orthopaedics and related research 20031001 |
| All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells. | Atherosclerosis 20031001 |
| Cholesterol oxidase and the hydroxymethylglutaryl coenzyme A reductase inhibitor mevinolin perturb endocytic trafficking in cultured vascular smooth muscle cells. | Journal of submicroscopic cytology and pathology 20031001 |
| Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment. | Circulation 20030930 |
| [Is type-2 diabetes mellitus preventable?]. | Orvosi hetilap 20030928 |
| IL-6 is a key factor in growth inhibition of human myeloma cells induced by pravastatin, an HMG-CoA reductase inhibitor. | International journal of oncology 20030901 |
| Protective effect of fluvastatin, an HMG-CoA reductase inhibitor, on the formation of 8-oxo-2'-deoxyguanosine in the nuclear DNA of hamster pancreas after a single administration of N-nitrosobis(2-oxopropyl)amine. | Biological & pharmaceutical bulletin 20030901 |
| Lovastatin induces relaxation and inhibits L-type Ca(2+) current in the rat basilar artery. | Pharmacology & toxicology 20030901 |
| Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells. | Cardiovascular research 20030901 |
| Pravastatin prevents arrhythmias induced by coronary artery ischemia/reperfusion in anesthetized normocholesterolemic rats. | Journal of pharmacological sciences 20030901 |
| Statins differ in their ability to block NF-kappaB activation in human blood monocytes. | International journal of clinical pharmacology and therapeutics 20030901 |
| Regression of an atherosclerotic coronary artery plaque demonstrated by multislice spiral computed tomography in a patient with stable angina pectoris. | Heart and vessels 20030901 |
| Role of the pharmacist in establishing lipid intervention programs. | Pharmacotherapy 20030901 |
| Increased expression of plasminogen activator inhibitor-1 by mediators of the acute phase response: a potential progenitor of vasculopathy in hypertensives. | Hypertension research : official journal of the Japanese Society of Hypertension 20030901 |
| Lack of adverse clopidogrel-atorvastatin clinical interaction from secondary analysis of a randomized, placebo-controlled clopidogrel trial. | Circulation 20030826 |
| Benefit-risk assessment of Rosuvastatin 10 to 40 milligrams. | The American journal of cardiology 20030821 |
| Long-chain omega-3 fatty acids from fish reduce sudden cardiac death in patients with coronary heart disease. | European journal of medical research 20030820 |
| Prospective serial evaluation of myocardial perfusion and lipids during the first six months of pravastatin therapy: coronary artery disease regression single photon emission computed tomography monitoring trial. | Journal of the American College of Cardiology 20030820 |
| Cloning of an emopamil-binding protein (EBP)-like protein that lacks sterol delta8-delta7 isomerase activity. | The Biochemical journal 20030815 |
| Syntheses of 3-ethylidenequinuclidine derivatives as squalene synthase inhibitors. Part 2: enzyme inhibition and effects on plasma lipid levels. | Bioorganic & medicinal chemistry 20030815 |
| Analytical methods for the quantitative determination of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in biological samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030815 |
| Plasma C-reactive protein as a marker of cardiac allograft vasculopathy in heart transplant recipients. | Journal of the American College of Cardiology 20030806 |
| Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane. | The Journal of pharmacology and experimental therapeutics 20030801 |
| Pharmacokinetics and pharmacodynamics of pravastatin in children with familial hypercholesterolemia. | Clinical pharmacology and therapeutics 20030801 |
| Statins: new data in secondary prevention and diabetes. Pravastatin and simvastatin are the best-assessed statins. | Prescrire international 20030801 |
| Change in the protein level of mevalonate pyrophosphate decarboxylase in tissues of mouse by pravastatin. | Biological & pharmaceutical bulletin 20030801 |
| Improvement of serum oxidation by pravastatin might be one of the mechanisms by which endothelial function in dilated coronary artery segments is ameliorated. | Atherosclerosis 20030801 |
| Hypercholesterolemia. The evidence supports use of statins. | Geriatrics 20030801 |
| Mevastatin suppresses lipopolysaccharide-induced Rac activation in the human monocyte cell line THP-1. | Surgery 20030801 |
| A comparative study of the in vitro antioxidant activity of statins. | International journal of cardiology 20030801 |
| Combination of statins and hormone replacement therapy in postmenopausal women is associated with increased bone mineral density. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20030801 |
| [Value and role of lipid lowering therapy for cardiovascular prevention in the elderly]. | Annales de cardiologie et d'angeiologie 20030801 |
| [Long-term hypolipidemic treatment of mixed hyperlipidemia with a combination of statins and fibrates]. | Casopis lekaru ceskych 20030801 |
| Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. | Circulation 20030729 |
| Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells. | The Journal of biological chemistry 20030718 |
| Effect of pravastatin on intermediate-density and low-density lipoproteins containing apolipoprotein CIII in patients with diabetes mellitus. | The American journal of cardiology 20030715 |
| Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial). | The American journal of cardiology 20030715 |
| Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells. | The Journal of biological chemistry 20030711 |
| Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier. | The Journal of pharmacology and experimental therapeutics 20030701 |
| Obesity and hyperhomocysteinaemia after kidney transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030701 |
| The effect of statin therapy on ventricular late potentials in acute myocardial infarction. | International journal of cardiology 20030701 |
| Pilot study examining the effect of cholesterol lowering on platelet nitric oxide responsiveness and arterial stiffness in subjects with isolated mild hypercholesterolaemia. | Clinical and experimental pharmacology & physiology 20030701 |
| Acute vasodilator effects of HMG-CoA reductase inhibitors: involvement of PI3-kinase/Akt pathway and Kv channels. | Journal of cardiovascular pharmacology 20030701 |
| Influence of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors on endothelial nitric oxide synthase and the formation of oxidants in the vasculature. | Atherosclerosis 20030701 |
| Allocating funds for cardiovascular disease prevention in light of the NCEP ATP III guidelines. | The American journal of managed care 20030701 |
| Statin-associated memory loss: analysis of 60 case reports and review of the literature. | Pharmacotherapy 20030701 |
| Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins. | Molecular and cellular biochemistry 20030701 |
| Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. | BMJ (Clinical research ed.) 20030628 |
| Correlation of statin-increased platelet APP ratios and reduced blood lipids in AD patients. | Neurology 20030624 |
| ABCG2 transports sulfated conjugates of steroids and xenobiotics. | The Journal of biological chemistry 20030620 |
| Beneficial effects of simvastatin and pravastatin on cardiac allograft rejection and survival. | Journal of the American College of Cardiology 20030604 |
| Contribution of organic anion transporters to the renal uptake of anionic compounds and nucleoside derivatives in rat. | The Journal of pharmacology and experimental therapeutics 20030601 |
| Pilot study describing the use of pravastatin in pediatric renal transplant recipients. | Pediatric transplantation 20030601 |
| Effect of pravastatin on loss of renal function in people with moderate chronic renal insufficiency and cardiovascular disease. | Journal of the American Society of Nephrology : JASN 20030601 |
| Cost effectiveness of statin therapy for the primary prevention of major coronary events in individuals with type 2 diabetes. | Diabetes care 20030601 |
| Molecular mechanism for inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by rosuvastatin. | Biochemical Society transactions 20030601 |
| Apo A-I promoter polymorphism influences basal HDL-cholesterol and its response to pravastatin therapy. | Atherosclerosis 20030601 |
| Biosynthetic maturation of the corpus allatum of the female adult medfly, Ceratitis capitata, and its putative control. | Journal of insect physiology 20030601 |
| Reduction in serum total cholesterol and risks of coronary events and cerebral infarction in Japanese men: the Kyushu Lipid Intervention Study. | Circulation journal : official journal of the Japanese Circulation Society 20030601 |
| Antioxidative potential of fluvastatin via the inhibition of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity. | Biological & pharmaceutical bulletin 20030601 |
| The combination of nebivolol plus pravastatin is associated with a more beneficial metabolic profile compared to that of atenolol plus pravastatin in hypertensive patients with dyslipidemia: a pilot study. | Journal of cardiovascular pharmacology and therapeutics 20030601 |
| Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance. | Clinical pharmacology and therapeutics 20030601 |
| Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics. | Clinical pharmacology and therapeutics 20030601 |
| Collision-induced dissociation of the negative ions of simvastatin hydroxy acid and related species. | Journal of mass spectrometry : JMS 20030601 |
| Evaluation of the synergistic adverse effects of concomitant therapy with statins and fibrates on rhabdomyolysis. | The Journal of pharmacy and pharmacology 20030601 |
| Serum lipid comparison in patients treated by statins or fibrates: existence of bad HDL-C responders to statins. | Acta cardiologica 20030601 |
| Current perspectives on statins. | Journal of the Indian Medical Association 20030601 |
| Determination of cholesterol-lowering statin drugs in aqueous samples using liquid chromatography-electrospray ionization tandem mass spectrometry. | Journal of chromatography. A 20030523 |
| [Coronary disease prevention: only the inhibition of inflammation is important. Why lower lipids, too?]. | MMW Fortschritte der Medizin 20030522 |
| Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events. | Circulation 20030520 |
| Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK). | The Journal of biological chemistry 20030516 |
| [HIV-infection, HAART (highly-active antiretroviral therapy) and hyperlipidemia]. | Deutsche medizinische Wochenschrift (1946) 20030509 |
| Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses. | Blood 20030501 |
| LDL containing apolipoprotein CIII is an independent risk factor for coronary events in diabetic patients. | Arteriosclerosis, thrombosis, and vascular biology 20030501 |
| DD ACE gene polymorphism is associated with increased coronary artery endothelial dysfunction: the PREFACE trial. | Heart (British Cardiac Society) 20030501 |
| Acute pancreatitis due to pravastatin therapy. | JOP : Journal of the pancreas 20030501 |
| Different effect induced by treatment with several statins on monocyte tissue factor expression in hypercholesterolemic subjects. | Clinical and experimental medicine 20030501 |
| Effects of simvastatin and pravastatin on peroxidation of erythrocyte plasma membrane lipids in patients with type 2 hypercholesterolemia. | Canadian journal of physiology and pharmacology 20030501 |
| [Caution about the use of statins in elderly individuals]. | Revista medica de Chile 20030501 |
| Combination lipid-lowering therapy with statins: safety issues in the postcerivastatin era. | Expert opinion on drug safety 20030501 |
| Lovastatin and phospholipase Cgamma regulate constitutive and protein kinase C dependent integrin mediated interactions of human T-cells with collagen. | Cellular immunology 20030501 |
| The future of lipid-lowering therapy: the big picture. | The Netherlands journal of medicine 20030501 |
| Ezetimibe: a novel option for lowering cholesterol. | Expert review of cardiovascular therapy 20030501 |
| Statin therapy and small fibre neuropathy: a serial electrophysiological study. | Journal of the neurological sciences 20030415 |
| Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415 |
| Statins and fibrates for the treatment of hyperlipidaemia in HIV-infected patients receiving HAART. | AIDS (London, England) 20030411 |
| High-density lipoprotein subpopulations in pathologic conditions. | The American journal of cardiology 20030403 |
| Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training. | American journal of physiology. Heart and circulatory physiology 20030401 |
| Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins. | Molecular pharmacology 20030401 |
| The 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor pravastatin reduces disease activity and inflammation in dextran-sulfate induced colitis. | The Journal of pharmacology and experimental therapeutics 20030401 |
| A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis. | Nature genetics 20030401 |
| Results of two clinical trials on the safety and efficacy of pravastatin 80 and 160 mg per day. | The American journal of cardiology 20030401 |
| Effect of pravastatin on cardiovascular events and mortality in 1516 women with coronary heart disease: results from the Long-Term Intervention with Pravastatin in Ischemic Disease (LIPID) study. | American heart journal 20030401 |
| Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease. | Archives of neurology 20030401 |
| The power of statins: aggressive lipid lowering. | Clinical cardiology 20030401 |
| Lipid-lowering therapy and risk of coronary events. | JAMA 20030401 |
| Lipid-lowering therapy and risk of coronary events. | JAMA 20030401 |
| Lipid-lowering therapy and risk of coronary events. | JAMA 20030401 |
| Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. | European heart journal 20030401 |
| Effects of cholesterol-lowering therapy on pressor hyperreactivity to stress in hypercholesterolemic patients. | Hypertension research : official journal of the Japanese Society of Hypertension 20030401 |
| Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin. | Xenobiotica; the fate of foreign compounds in biological systems 20030401 |
| More on PROSPER. | Lancet (London, England) 20030329 |
| More on PROSPER. | Lancet (London, England) 20030329 |
| Safety and statin therapy: reconsidering the risks and benefits. | Archives of internal medicine 20030324 |
| Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials. | Archives of internal medicine 20030324 |
| Mevastatin can cause G1 arrest and induce apoptosis in pulmonary artery smooth muscle cells through a p27Kip1-independent pathway. | Circulation research 20030321 |
| The sorry saga of the statins in New Zealand--pharmacopolitics versus patient care. | The New Zealand medical journal 20030314 |
| [Fewer myocardial infarcts. Statin therapy is even effective in the elderly]. | MMW Fortschritte der Medizin 20030313 |
| Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. | Journal of biotechnology 20030306 |
| Efficacy of rosuvastatin compared with other statins at selected starting doses in hypercholesterolemic patients and in special population groups. | The American journal of cardiology 20030306 |
| Guidelines for lowering lipids to reduce coronary artery disease risk: a comparison of rosuvastatin with atorvastatin, pravastatin, and simvastatin for achieving lipid-lowering goals. | The American journal of cardiology 20030306 |
| Lipid and apolipoprotein ratios: association with coronary artery disease and effects of rosuvastatin compared with atorvastatin, pravastatin, and simvastatin. | The American journal of cardiology 20030306 |
| Effects of bezafibrate and pravastatin on remnant-like lipoprotein particles and lipoprotein subclasses in type 2 diabetes. | Diabetes research and clinical practice 20030301 |
| Non-high-density lipoprotein cholesterol: a target of lipid-lowering in dialysis patients. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20030301 |
| Statin effects on cholesterol micro-domains in brain plasma membranes. | Biochemical pharmacology 20030301 |
| Treating dyslipidemia with statins: the risk-benefit profile. | American heart journal 20030301 |
| Statins inhibit high glucose-mediated neutrophil-endothelial cell adhesion through decreasing surface expression of endothelial adhesion molecules by stimulating production of endothelial nitric oxide. | Microvascular research 20030301 |
| High praise for an old standby. Low-cost diuretics excel in combating high blood pressure. | Heart advisor 20030301 |
| Pravastatin protection from cold stress in myocardium of rats. | Japanese heart journal 20030301 |
| [Cardiac rehabilitation in a HIV-patient treated with protease inhibitors]. | Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20030301 |
| Prevention of nitrate tolerance by long-term treatment with statins. | Cardiovascular drugs and therapy 20030301 |
| [Statin treatment in type 2 diabetes. Is it a must today?]. | MMW Fortschritte der Medizin 20030227 |
| Reduced connexin43 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice. | Circulation 20030225 |
| [After several years of statin therapy. Long-term prevention of cardiac death]. | MMW Fortschritte der Medizin 20030220 |
| Pharmacologic plaque passivation for the reduction of recurrent cardiac events in acute coronary syndromes. | Journal of the American College of Cardiology 20030219 |
| Inhibition of cdk2 activating phosphorylation by mevastatin. | The Journal of biological chemistry 20030214 |
| Trafficking of cholesterol from cell bodies to distal axons in Niemann Pick C1-deficient neurons. | The Journal of biological chemistry 20030207 |
| Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression. | Leukemia research 20030201 |
| Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin. | Atherosclerosis 20030201 |
| Does pravastatin affect circulating levels of soluble TNF receptor 2 in hypercholesterolemic patients? | Atherosclerosis 20030201 |
| Pravastatin inhibits pro-inflammatory effects of Alzheimer's peptide Abeta(1-42) in glioma cell culture in vitro. | Pharmacological research 20030201 |
| Levels of adhesion molecules do not decrease after 3 months of statin therapy in moderate hypercholesterolaemia. | Clinical science (London, England : 1979) 20030201 |
| The PROSPER trial. | Lancet (London, England) 20030201 |
| The PROSPER trial. | Lancet (London, England) 20030201 |
| The PROSPER trial. | Lancet (London, England) 20030201 |
| The PROSPER trial. | Lancet (London, England) 20030201 |
| The PROSPER trial. | Lancet (London, England) 20030201 |
| Inhibitor studies of isopentenyl pyrophosphate biosynthesis in suspension cultures of the yew Taxus chinensis var. mairei. | Biotechnology and applied biochemistry 20030201 |
| Effect of atorvastatin and pravastatin on serum C-reactive protein. | American heart journal 20030201 |
| Muscular adverse effects of statins. | Prescrire international 20030201 |
| Statins can inhibit proliferation of human breast cancer cells in vitro. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030201 |
| Statin fails to meet expectations. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030201 |
| Comparison of the effect of two HMG CoA reductase inhibitors on LDL susceptibility to oxidation. | Arquivos brasileiros de cardiologia 20030201 |
| Modulation of the inflammatory process by statins. | Drugs of today (Barcelona, Spain : 1998) 20030201 |
| Alcohol consumption and plasma concentration of C-reactive protein. | Circulation 20030128 |
| Pravastatin for secondary prevention of cardiovascular events in persons with mild chronic renal insufficiency. | Annals of internal medicine 20030121 |
| Summaries for patients. Treating cholesterol in patients with mild kidney disease. | Annals of internal medicine 20030121 |
| Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interaction. | Circulation 20030107 |
| Transformations of cyclic nonaketides by Aspergillus terreus mutants blocked for lovastatin biosynthesis at the lovA and lovC genes. | Organic & biomolecular chemistry 20030107 |
| High-performance liquid chromatography coupled with negative ion tandem mass spectrometry for determination of pravastatin in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105 |
| Comparison of micronized fenofibrate and pravastatin in patients with primary hyperlipidemia. | Journal of cardiovascular pharmacology 20030101 |
| Statins regulate alpha2beta1-integrin expression and collagen I-dependent functions in human vascular smooth muscle cells. | Journal of cardiovascular pharmacology 20030101 |
| Statin therapy in the elderly-the evidence mounts. | The American journal of geriatric cardiology 20030101 |
| The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA reductase activity. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030101 |
| Cerivastatin and atorvastatin inhibit IL-3-dependent differentiation and IgE-mediated histamine release in human basophils and downmodulate expression of the basophil-activation antigen CD203c/E-NPP3. | Journal of leukocyte biology 20030101 |
| Ubiquinone does not rescue acute myeloid leukemia cells from growth inhibition by statins. | Leukemia 20030101 |
| Drug-induced, Ro/SSA-positive cutaneous lupus erythematosus. | Archives of dermatology 20030101 |
| Comparing HMG-CoA reductase inhibitors. | Clinical cardiology 20030101 |
| Treating hypercholesterolemia: looking forward. | Clinical cardiology 20030101 |
| Implementing guidelines in primary care: can population impact measures help? | BMC public health 20030101 |
| hsCRP and HDL effects of statins trial (CHEST): rapid effect of statin therapy on C-reactive protein and high-density lipoprotein levels A clinical investigation. | Heart disease (Hagerstown, Md.) 20030101 |
| Rosuvastatin: a new HMG-CoA reductase inhibitor for the treatment of hypercholesterolemia. | Heart disease (Hagerstown, Md.) 20030101 |
| Influence of diabetes mellitus on heart failure risk and outcome. | Cardiovascular diabetology 20030101 |
| Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients. | Drugs 20030101 |
| The development of combination drugs for atherosclerosis. | Current atherosclerosis reports 20030101 |
| Hepatobiliary transport of a nonpeptidic endothelin antagonist, (+)-(5S,6R,7R)-2-butyl-7-[2((2S)-2-carboxypropyl)-4-methoxyphenyl]-5-(3,4-methylenedioxyphenyl) cyclopentenol[1,2-b]pyridine-6-carboxylic acid: uptake by isolated rat hepatocytes and canalicular membrane vesicles. | Pharmaceutical research 20030101 |
| Preventing angiographic progression of coronary atherosclerosis with pravastatin. | Journal of atherosclerosis and thrombosis 20030101 |
| Statin therapy in the elderly: does it make good clinical and economic sense? | Drugs & aging 20030101 |
| [Clinical study of the month. The ALLHAT-LLT trial]. | Revue medicale de Liege 20030101 |
| A model to assess the cost effectiveness of statins in achieving the UK National Service Framework target cholesterol levels. | PharmacoEconomics 20030101 |
| An economic analysis of the Atorvastatin Comparative Cholesterol Efficacy and Safety Study (ACCESS). | PharmacoEconomics 20030101 |
| Statins stimulate arachidonic acid release and prostaglandin I2 production in rat liver cells. | Lipids in health and disease 20030101 |
| Pravastatin benefits elderly patients: results of PROSPER study. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20030101 |
| LIFE and ARBITER. | Preventive cardiology 20030101 |
| Variable influence of statins on isoprostanes in hyperlipidemia. | Advances in experimental medicine and biology 20030101 |
| Twice-daily amprenavir 1200 mg versus amprenavir 600 mg/ritonavir 100 mg, in combination with at least 2 other antiretroviral drugs, in HIV-1-infected patients. | BMC infectious diseases 20030101 |
| [Drug interactions with antilipemics]. | Therapie 20030101 |
| Put your heart into the joint benefits of statins! | Arthritis research & therapy 20030101 |
| HMG-CoA reductase inhibitors inhibit inducible nitric oxide synthase gene expression in macrophages. | Journal of biomedical science 20030101 |
| Rosuvastatin--a highly effective new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor: review of clinical trial data at 10-40 mg doses in dyslipidemic patients. | Cardiology 20030101 |
| Pravastatin lowered coronary disease risk in elderly persons with or at risk for vascular disease. | ACP journal club 20030101 |
| Pravastatin was not better than usual care in reducing all-cause mortality or CHD events. | ACP journal club 20030101 |
| Potential nontraditional applications of statins. | The Annals of pharmacotherapy 20030101 |
| Effect of statins combined with estradiol on the proliferation of human receptor-positive and receptor-negative breast cancer cells. | Menopause (New York, N.Y.) 20030101 |
| HMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotection. | BMC cardiovascular disorders 20030101 |
| HIV protease inhibitors and dyslipidemia. | AIDS reviews 20030101 |
| [Markers of inflammation and platelet aggregation in patients with non ST elevation acute coronary syndrome treated with atorvastatin or pravastatin]. | Kardiologiia 20030101 |
| [Non ST elevation acute coronary syndrome: early use of pravastatin or atorvastatin is associated with divergent changes of parameters of hemostasis]. | Kardiologiia 20030101 |
| Gastrointestinal cancer and the long-term use of pravastatin in the elderly. | Acta oncologica (Stockholm, Sweden) 20030101 |
| Rosuvastatin achieves new standards in lipid management. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20030101 |
| Cholesterol-lowering action of policosanol compares well to that of pravastatin and lovastatin. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20030101 |
| A review of anabolic therapies for osteoporosis. | Arthritis research & therapy 20030101 |
| [Pharmacologic characteristics of rosuvastatin, a new HMG-CoA reductase inhibitor]. | Therapie 20030101 |
| Clinical pharmacokinetics of statins. | Methods and findings in experimental and clinical pharmacology 20030101 |
| [Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized]. | MMW Fortschritte der Medizin 20030101 |
| Home-based versus hospital-based cardiac rehabilitation after myocardial infarction or revascularisation: design and rationale of the Birmingham Rehabilitation Uptake Maximisation Study (BRUM): a randomised controlled trial [ISRCTN72884263]. | BMC cardiovascular disorders 20030101 |
| [Results of clinical evidence: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)]. | Kardiologiia 20030101 |
| Molecular regulation of cholesterol biosynthesis: implications in carcinogenesis. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20030101 |
| Pharmacological comparison of the statins. | Arzneimittel-Forschung 20030101 |
| Cerivastatin ameliorates high insulin-enhanced neutrophil-endothelial cell adhesion and endothelial intercellular adhesion molecule-1 expression by inhibiting mitogen-activated protein kinase activation. | Journal of diabetes and its complications 20030101 |
| Platelet-neutrophil conjugate formation is increased in diabetic women with cardiovascular disease. | Cardiovascular diabetology 20030101 |
| Are statins indicated for the primary prevention of coronary heart disease in octogenarians? protagonist viewpoint. | The American journal of geriatric cardiology 20030101 |
| Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor. | Cardiovascular drug reviews 20030101 |
| Statin stimulates bone morphogenetic protein-2, aggrecan, and type 2 collagen gene expression and proteoglycan synthesis in rat chondrocytes. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20030101 |
| Pravastatin: a review of its use in elderly patients. | Drugs & aging 20030101 |
| Differential effects of fenofibrate versus atorvastatin on the concentrations of E-selectin and vascular cellular adhesion molecule-1 in patients with type 2 diabetes mellitus and mixed hyperlipoproteinemia: a randomized cross-over trial. | Cardiovascular diabetology 20030101 |
| Ultrastructure of mouse striated muscle fibers following pravastatin administration. | Journal of muscle research and cell motility 20030101 |
| What ALLHAT tells us about treating high-risk patients with hypertension and hyperlipidemia. | The Journal of cardiovascular nursing 20030101 |
| Hypergravity-induced changes in gene expression in Arabidopsis hypocotyls. | Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20030101 |
| Comparison of the efficacy of rosuvastatin versus atorvastatin, simvastatin, and pravastatin in achieving lipid goals: results from the STELLAR trial. | Current medical research and opinion 20030101 |
| Characteristics and lipid distribution of a large, high-risk, hypertensive population: the lipid-lowering component of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). | Journal of clinical hypertension (Greenwich, Conn.) 20030101 |
| Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA. | BioFactors (Oxford, England) 20030101 |
| Ezetimibe. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101 |
| Monocyte chemoattractant protein-1 and CC-chemokine receptor-2 in severe hypercholesterolaemia. | Scandinavian journal of clinical and laboratory investigation 20030101 |
| Statins in hypercholesterolaemia: a dose-specific meta-analysis of lipid changes in randomised, double blind trials. | BMC family practice 20030101 |
| Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults. | Vascular medicine (London, England) 20030101 |
| Uptake mechanism of pitavastatin, a new inhibitor of HMG-CoA reductase, in rat hepatocytes. | Drug metabolism and pharmacokinetics 20030101 |
| Simvastatin and pravastatin equally improve flow-mediated dilation in males with hypercholesterolemia. | Wiener klinische Wochenschrift 20021230 |
| Receptor-dependent regulation of the CYP3A4 gene. | Toxicology 20021227 |
| Toxicological implications of hepatobiliary transporters. | Toxicology 20021227 |
| Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins. | Brain research 20021220 |
| Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). | JAMA 20021218 |
| The ALLHAT lipid lowering trial--less is less. | JAMA 20021218 |
| Chelation-controlled reduction: stereoselective formation of syn-1,3-diols and synthesis of compactin and mevinolin lactone. | The Journal of organic chemistry 20021213 |
| Protecting the heart: a practical review of the statin studies. | MedGenMed : Medscape general medicine 20021210 |
| [Even in advanced age: statins prevent infarct]. | MMW Fortschritte der Medizin 20021205 |
| [Statins for all seniors?]. | MMW Fortschritte der Medizin 20021205 |
| Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20021201 |
| Association of pravastatin and left ventricular mass in hypercholesterolemic patients: role of 8-iso-prostaglandin f2alpha formation. | Journal of cardiovascular pharmacology 20021201 |
| Fluvastatin induces apoptosis in rat neonatal cardiac myocytes: a possible mechanism of statin-attenuated cardiac hypertrophy. | Journal of cardiovascular pharmacology 20021201 |
| [Comparative study of the impact of diet versus pravastatin on color vision in Brodman area 19 detected by computerized chromatic analysis (CARDIOCOLOUR Study)]. | Revista espanola de cardiologia 20021201 |
| Statin inhibits leukocyte-endothelial interaction and prevents neuronal death induced by ischemia-reperfusion injury in the rat retina. | Archives of ophthalmology (Chicago, Ill. : 1960) 20021201 |
| Risk factors for non-haemorrhagic stroke in patients with coronary heart disease and the effect of lipid-modifying therapy with pravastatin. | Journal of hypertension 20021201 |
| Targeting cardiovascular risk associated with both low density and high density lipoproteins using statin-niacin combination therapy. | Journal of cardiovascular risk 20021201 |
| Endothelial nitric oxide synthase genotype modulates the improvement of coronary blood flow by pravastatin: a placebo-controlled PET study. | Journal of molecular medicine (Berlin, Germany) 20021201 |
| Management of dyslipidemia in the high-risk patient. | American heart journal 20021201 |
| Efficacy and safety of rosuvastatin compared with pravastatin and simvastatin in patients with hypercholesterolemia: a randomized, double-blind, 52-week trial. | American heart journal 20021201 |
| Inhibition of cholesterol synthesis causes both hypercholesterolemia and hypocholesterolemia in hamsters. | Biological & pharmaceutical bulletin 20021201 |
| Statins do not meet expectations for lowering low-density lipoprotein cholesterol levels when used in clinical practice. | The American journal of medicine 20021201 |
| Measuring the cost-effectiveness of lipid-lowering drugs in the elderly: the outcomes research and economic analysis components of the PROSPER trial. | Controlled clinical trials 20021201 |
| Time-dependent effect of statins on platelet function in hypercholesterolaemia. | European journal of clinical investigation 20021201 |
| Chlamydiae host cell interactions revealed using DNA microarrays. | Annals of the New York Academy of Sciences 20021201 |
| An examination of the effect of cytochrome P450 drug interactions of hydroxymethylglutaryl-coenzyme A reductase inhibitors on health care utilization: a Canadian population-based study. | Clinical therapeutics 20021201 |
| Enzyme inhibitors to increase poly-3-hydroxybutyrate production by transgenic tobacco. | Bioscience, biotechnology, and biochemistry 20021201 |
| Differing effects of low-dose estrogen-progestin therapy and pravastatin in postmenopausal hypercholesterolemic women. | Climacteric : the journal of the International Menopause Society 20021201 |
| [The PROSPER Study (PROspective study of pravastatin in the elderly at risk)]. | Revue medicale de Liege 20021201 |
| Toward a role for statins in immunomodulation. | Molecular interventions 20021201 |
| [Treatment with statins: further data from the Heart Protection Study]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20021130 |
| Statin-induced myositis migrans. | Wiener klinische Wochenschrift 20021130 |
| High-risk elderly patients PROSPER from cholesterol-lowering therapy. | Lancet (London, England) 20021123 |
| Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. | Lancet (London, England) 20021123 |
| Contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthesis of gibberellins in Arabidopsis. | The Journal of biological chemistry 20021122 |
| Comparative beneficial effects of simvastatin and pravastatin on cardiac allograft rejection and survival. | Journal of the American College of Cardiology 20021106 |
| Regulation of interleukin-8 expression by HMG-CoA reductase inhibitors in human vascular smooth muscle cells. | Atherosclerosis 20021101 |
| Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study. | Atherosclerosis 20021101 |
| Association of factor VII levels with inflammatory parameters in hypercholesterolemic patients. | Atherosclerosis 20021101 |
| Beyond lipid lowering: the role of statins in vascular protection. | International journal of cardiology 20021101 |
| Liver-specific distribution of rosuvastatin in rats: comparison with pravastatin and simvastatin. | Drug metabolism and disposition: the biological fate of chemicals 20021101 |
| Squalestatin 1-inducible expression of rat CYP2B: evidence that an endogenous isoprenoid is an activator of the constitutive androstane receptor. | Molecular pharmacology 20021101 |
| Early statin therapy for acute coronary syndromes. | The Annals of pharmacotherapy 20021101 |
| Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021101 |
| Plasminogen activator inhibitor-1: physiologic role, regulation, and the influence of common pharmacologic agents. | Journal of clinical pharmacology 20021101 |
| 3-hydroxy-3-methylglutaryl coenzyme A reductase-independent inhibition of CD40 expression by atorvastatin in human endothelial cells. | Arteriosclerosis, thrombosis, and vascular biology 20021101 |
| Functional analysis of mlcR, a regulatory gene for ML-236B (compactin) biosynthesis in Penicillium citrinum. | Molecular genetics and genomics : MGG 20021101 |
| Zeroing in on how low cholesterol should go. | Heart advisor 20021101 |
| Pravastatin promotes coronary collateral circulation in patients with coronary artery disease. | Coronary artery disease 20021101 |
| Preclinical pharmacokinetics of statins. | Methods and findings in experimental and clinical pharmacology 20021101 |
| Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin. | European journal of pharmacology 20021025 |
| Cholesterol-lowering therapy with pravastatin in patients with average cholesterol levels and established ischaemic heart disease: is it cost-effective? | The Medical journal of Australia 20021021 |
| Low-density lipoprotein lowering and atherosclerosis progression: does more mean less? | Circulation 20021015 |
| ARBITER: Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol: a randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness. | Circulation 20021015 |
| The lower the LDL, the better. | Circulation 20021015 |
| Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients. | Atherosclerosis 20021001 |
| A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system. | The Journal of pharmacology and experimental therapeutics 20021001 |
| Testing cognitive function in elderly populations: the PROSPER study. PROspective Study of Pravastatin in the Elderly at Risk. | Journal of neurology, neurosurgery, and psychiatry 20021001 |
| Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, are able to reduce superoxide anion production by NADPH oxidase in THP-1-derived monocytes. | Journal of cardiovascular pharmacology 20021001 |
| Factors affecting low-density lipoprotein and high-density lipoprotein cholesterol response to pravastatin in the West Of Scotland Coronary Prevention Study (WOSCOPS). | The American journal of cardiology 20021001 |
| Frequency of new coronary events in older persons with peripheral arterial disease and serum low-density lipoprotein cholesterol > or = 125 mg/dl treated with statins versus no lipid-lowering drug. | The American journal of cardiology 20021001 |
| Severe rhabdomyolysis after laparoscopic surgery for adenocarcinoma of the rectum in two patients treated with statins. | Anesthesiology 20021001 |
| Statin lipid-lowering therapy for acute myocardial infarction and unstable angina: efficacy and mechanism of benefit. | Mayo Clinic proceedings 20021001 |
| Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001 |
| Antioxidative effects of fluvastatin and its metabolites against DNA damage in streptozotocin-treated mice. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001 |
| Evaluation and management of dyslipidemia in patients with HIV infection. | Journal of general internal medicine 20021001 |
| Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosporin A. | International journal of clinical pharmacology and therapeutics 20021001 |
| Clinical inquiries. What is the target for low-density lipoprotein cholesterol in patients with heart disease? | The Journal of family practice 20021001 |
| [A survey on the status of lipid-lowering therapy in 180 hypercholesterolemic patients]. | Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20021001 |
| Prevention of chronic rejection by pravastatin in a rat kidney transplant model. | Transplantation 20020927 |
| Reducing the risk for stroke in patients with myocardial infarction: a Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) substudy. | Circulation 20020924 |
| Lipid modification of proteins in Archaea: attachment of a mevalonic acid-based lipid moiety to the surface-layer glycoprotein of Haloferax volcanii follows protein translocation. | The Biochemical journal 20020915 |
| Statin treatment following coronary artery stenting and one-year survival. | Journal of the American College of Cardiology 20020904 |
| Clinical implications of statin event trials. | Current atherosclerosis reports 20020901 |
| Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20020901 |
| Effects of phalloidin on the biliary excretion of cholephilic compounds in rats. | Pharmacology 20020901 |
| Effects of pravastatin sodium on mevalonate metabolism in common marmosets. | Journal of biochemistry 20020901 |
| A review of the pharmacologic and pharmacokinetic aspects of rosuvastatin. | Journal of clinical pharmacology 20020901 |
| Update on the management of dyslipidemia. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020901 |
| Japanese familial hypercholesterolaemia with a 327insC mutation in the LDL receptor gene. | Annals of clinical biochemistry 20020901 |
| Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol. | Arteriosclerosis, thrombosis, and vascular biology 20020901 |
| [Utility of pravastin in cardiac transplant dyslipidemia]. | Revista clinica espanola 20020901 |
| Effect of increased dosage of the ML-236B (compactin) biosynthetic gene cluster on ML-236B production in Penicillium citrinum. | Molecular genetics and genomics : MGG 20020901 |
| Management of dyslipidemia in the primary prevention of coronary heart disease. | Current opinion in cardiology 20020901 |
| [Primary prevention of diabetes mellitus by pharmacological intervention]. | Nihon rinsho. Japanese journal of clinical medicine 20020901 |
| Massive postoperative rhabdomyolysis following combined CABG/abdominal aortic replacement: a possible association with HMG-CoA reductase inhibitors. | Cardiovascular drugs and therapy 20020901 |
| [Antilipemic agents in combined therapy]. | Orvosi hetilap 20020825 |
| Pravastatin and Aspirin. | Circulation 20020806 |
| Sex difference in inhibition of in vitro mexazolam metabolism by various 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors in rat liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20020801 |
| Chronic hydroxymethylglutaryl coenzyme a reductase inhibition and endothelial function of the normocholesterolemic rat: comparison with angiotensin-converting enzyme inhibition. | Journal of cardiovascular pharmacology 20020801 |
| Pravastatin does not alter protease inhibitor exposure or virologic efficacy during a 24-week period of therapy. | Journal of acquired immune deficiency syndromes (1999) 20020801 |
| Reduction of bFGF-induced smooth muscle cell proliferation and endothelin receptor mRNA expression by mevastatin and atorvastatin. | Biochemical pharmacology 20020801 |
| Pharmacology of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), including rosuvastatin and pitavastatin. | Journal of clinical pharmacology 20020801 |
| HMG-CoA reductase inhibition and PPAR- alpha activation both inhibit cyclosporin A induced endothelin-1 secretion in cultured endothelial cells. | Clinical science (London, England : 1979) 20020801 |
| The potential of pill splitting to achieve cost savings. | The American journal of managed care 20020801 |
| Early use of pravastatin in patients with acute myocardial infarction undergoing coronary angioplasty. | Acta cardiologica 20020801 |
| The HMG Co-A reductase inhibitors ('statins') and myotoxic effects. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020801 |
| The extent of late in-stent neointima formation is modified by treatment with pravastatin: a preliminary study with intravascular ultrasound. | Italian heart journal : official journal of the Italian Federation of Cardiology 20020801 |
| Association between enhanced soluble CD40L and prothrombotic state in hypercholesterolemia: effects of statin therapy. | Circulation 20020723 |
| Relations of lipoprotein subclass levels and low-density lipoprotein size to progression of coronary artery disease in the Pravastatin Limitation of Atherosclerosis in the Coronary Arteries (PLAC-I) trial. | The American journal of cardiology 20020715 |
| Effect of pravastatin on apolipoproteins B and C-III in very-low-density lipoproteins and low-density lipoproteins. | The American journal of cardiology 20020715 |
| Rho/Rho-kinase is involved in the synthesis of tissue factor in human monocytes. | Atherosclerosis 20020701 |
| Effect of pravastatin on proteinuria in patients with well-controlled hypertension. | Hypertension (Dallas, Tex. : 1979) 20020701 |
| Effects of combined treatment with pravastatin and ursodeoxycholic acid on hepatic cholesterol metabolism. | European journal of clinical investigation 20020701 |
| Are some statins more equal than others. | Diabetes, obesity & metabolism 20020701 |
| Molecular cloning and characterization of an ML-236B (compactin) biosynthetic gene cluster in Penicillium citrinum. | Molecular genetics and genomics : MGG 20020701 |
| Why stopping drugs abruptly can endanger cardiac recovery. | Heart advisor 20020701 |
| Resource management in prevention of coronary heart disease: optimising prescription of lipid-lowering drugs. | Lancet (London, England) 20020629 |
| Inhibition of Rho/Rho-kinase signaling downregulates plasminogen activator inhibitor-1 synthesis in cultured human monocytes. | Biochimica et biophysica acta 20020612 |
| Increased transforming growth factor-beta(1) circulating levels and production in human monocytes after 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase inhibition with pravastatin. | Journal of the American College of Cardiology 20020605 |
| Effects of pravastatin in the elderly. | Annals of internal medicine 20020604 |
| Cholestasis associated with the use of pravastatin sodium. | The Medical journal of Australia 20020603 |
| Pravastatin sodium, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, decreases serum total cholesterol in Japanese White rabbits by two different mechanisms. | Atherosclerosis 20020601 |
| A 16-week fenofibrate treatment increases LDL particle size in type IIA dyslipidemic patients. | Atherosclerosis 20020601 |
| A randomized, double-blind trial comparing the efficacy and safety of pitavastatin versus pravastatin in patients with primary hypercholesterolemia. | Atherosclerosis 20020601 |
| Apolipoprotein A-I deficiency with accumulated risk for CHD but no symptoms of CHD. | Atherosclerosis 20020601 |
| Extremely high dose pravastatin may suppress amyloidogenesis in a mouse model. | Annals of the rheumatic diseases 20020601 |
| Isotopomer spectral analysis of intermediates of cholesterol synthesis in human subjects and hepatic cells. | American journal of physiology. Endocrinology and metabolism 20020601 |
| Effect of apoE genotype on the hypolipidaemic response to pravastatin in an outpatient setting. | Journal of internal medicine 20020601 |
| A randomized crossover trial of combination pharmacologic therapy in children with familial hyperlipidemia. | Pediatric research 20020601 |
| Implementation of a therapeutic-interchange clinic for HMG-CoA reductase inhibitors. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020601 |
| Pravastatin treatment-associated reduction in plasma homocysteine in heart-transplanted patients. | Transplantation proceedings 20020601 |
| The history of antibiotics: the Japanese story. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20020601 |
| Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects. | Journal of neuroscience research 20020601 |
| Policosanol: a new treatment for cardiovascular disease? | Alternative medicine review : a journal of clinical therapeutic 20020601 |
| Statin therapy: rationale for a new agent, rosuvastatin. | International journal of clinical practice 20020601 |
| Gateways to Clinical Trials. June 2002. | Methods and findings in experimental and clinical pharmacology 20020601 |
| Safety and tolerability of pravastatin in long-term clinical trials: prospective Pravastatin Pooling (PPP) Project. | Circulation 20020521 |
| Cost-effectiveness of intensive glycemic control, intensified hypertension control, and serum cholesterol level reduction for type 2 diabetes. | JAMA 20020515 |
| Effects of streptozotocin-induced diabetes on acetoacetyl-CoA synthetase activity in rats. | Biochemical pharmacology 20020515 |
| Importance of NAD(P)H oxidase-mediated oxidative stress and contractile type smooth muscle myosin heavy chain SM2 at the early stage of atherosclerosis. | Circulation 20020514 |
| Statins and risk of polyneuropathy: a case-control study. | Neurology 20020514 |
| Statin use, hyperlipidaemia, and the risk of breast cancer. | British journal of cancer 20020506 |
| A comparison of pravastatin and gemfibrozil in the treatment of dyslipoproteinemia in patients with non-insulin-dependent diabetes mellitus. | Atherosclerosis 20020501 |
| Statin use and the risk of breast and prostate cancer. | Epidemiology (Cambridge, Mass.) 20020501 |
| Atorvastatin inhibition of cytokine-inducible nitric oxide synthase expression in native endothelial cells in situ. | British journal of pharmacology 20020501 |
| Lipid-lowering drug use and cardiovascular events after myocardial infarction. | The Annals of pharmacotherapy 20020501 |
| [Results of clinical epidemiology and intervention trial of hyperlipidemia in Japan]. | Nihon rinsho. Japanese journal of clinical medicine 20020501 |
| Immunosuppressive effects of statins. | Atherosclerosis. Supplements 20020501 |
| Pharmacological interactions of statins. | Atherosclerosis. Supplements 20020501 |
| The choice of hormone replacement therapy or statin therapy in the treatment of hyperlipidemic postmenopausal women. | Atherosclerosis. Supplements 20020501 |
| Issues concerning the monitoring of statin therapy in hypercholesterolemic subjects with high plasma lipoprotein(a) levels. | Lipids 20020501 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020501 |
| Statins as immunomodulators. | Transplant immunology 20020501 |
| Comparison of the efficacy and safety of pravastatin and simvastatin in heart transplantation. | The Journal of the Association of Physicians of India 20020501 |
| Risk-benefit of HMG-CoA reductase inhibitors in the treatment of HIV protease inhibitor-related hyperlipidaemia. | Expert opinion on drug safety 20020501 |
| Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the LIPID trial follow-up. | Lancet (London, England) 20020420 |
| Interaction between ritonavir and statins. | The American journal of medicine 20020415 |
| Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae. | Atherosclerosis 20020401 |
| The effects of hydroxy-methyl-glutaryl co-enzyme A reductase inhibitors on platelet thrombus formation. | Atherosclerosis 20020401 |
| CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase. | Blood 20020401 |
| Comparison of low-density lipoprotein cholesterol lowering by pravastatin to <100 mg/dl versus >100 mg/dl on brachial artery vasoreactivity in patients with severe hypercholesterolemia and previous atherosclerotic events or diabetes mellitus. | The American journal of cardiology 20020401 |
| Design of the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT)-TIMI 22 trial. | The American journal of cardiology 20020401 |
| Influence of simvastatin, pravastatin, and BM 15.766 on neutral sterols in liver and testis of guinea pigs. | Metabolism: clinical and experimental 20020401 |
| Effects of hypocholesterolaemic agents on the expression and activity of 3-hydroxy-3-methylglutaryl-CoA reductase in the fat body of the German cockroach. | Archives of insect biochemistry and physiology 20020401 |
| Interleukin-6 -174G>C polymorphism and risk of coronary heart disease in West of Scotland coronary prevention study (WOSCOPS). | Arteriosclerosis, thrombosis, and vascular biology 20020401 |
| Drug-induced liver damage -- a three-year study of patients from one gastroenterological department. | Medical science monitor : international medical journal of experimental and clinical research 20020401 |
| Biosynthesis and biotechnological production of statins by filamentous fungi and application of these cholesterol-lowering drugs. | Applied microbiology and biotechnology 20020401 |
| A new reality: achieving cholesterol-lowering goals in clinical practice. | Atherosclerosis. Supplements 20020401 |
| The lower the better? Reviewing the evidence for more aggressive cholesterol reduction and goal attainment. | Atherosclerosis. Supplements 20020401 |
| Effect of vitamins C and E on progression of transplant-associated arteriosclerosis: a randomised trial. | Lancet (London, England) 20020330 |
| Coronary heart disease in patients with low LDL-cholesterol: benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factors. | Circulation 20020326 |
| Withdrawal of statins increases event rates in patients with acute coronary syndromes. | Circulation 20020326 |
| Relationship between lipid levels and clinical outcomes in the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Trial: to what extent is the reduction in coronary events with pravastatin explained by on-study lipid levels? | Circulation 20020312 |
| Pharmacokinetic interactions between protease inhibitors and statins in HIV seronegative volunteers: ACTG Study A5047. | AIDS (London, England) 20020308 |
| Managing dyslipidemia in the high-risk patient. | The American journal of cardiology 20020307 |
| [Myotoxicity and rhabdomyolisis due to statins]. | Nederlands tijdschrift voor geneeskunde 20020302 |
| 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and rhabdomyolysis: considerations in the renal failure patient. | Current opinion in nephrology and hypertension 20020301 |
| Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions. | The Journal of pharmacology and experimental therapeutics 20020301 |
| Early benefits of pravastatin to experimentally induced atherosclerosis. | Journal of cardiovascular pharmacology 20020301 |
| Beta-blockers are associated with lower C-reactive protein concentrations in patients with coronary artery disease. | The American journal of medicine 20020301 |
| Simvastatin and lovastatin, but not pravastatin, interact with MDR1. | The Journal of pharmacy and pharmacology 20020301 |
| Experimental model of escape phenomenon in hamsters and the effectiveness of YM-53601 in the model. | British journal of pharmacology 20020301 |
| Assessment of ADRs associated with lipid-lowering agents recorded in the Department of Internal Medicine, University Hospital, Jena. | International journal of clinical pharmacology and therapeutics 20020301 |
| Evaluation of myopathy risk for HMG-CoA reductase inhibitors by urethane infusion method. | Biological & pharmaceutical bulletin 20020301 |
| Effects of an HMG-CoA reductase inhibitor in combination with an ACE inhibitor or angiotensin II type 1 receptor antagonist on myocardial metabolism in ischemic rabbit hearts. | Hypertension research : official journal of the Japanese Society of Hypertension 20020301 |
| HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells. | Cardiovascular drugs and therapy 20020301 |
| Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia. | Expert opinion on investigational drugs 20020301 |
| Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2). | The Journal of biological chemistry 20020222 |
| Effects of probucol and pravastatin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia. Fukuoka Atherosclerosis Trial (FAST). | Journal of the American College of Cardiology 20020220 |
| Statins as novel therapies for osteoporosis? | European journal of obstetrics, gynecology, and reproductive biology 20020210 |
| Expedient, stereocontrolled synthesis of (+)-compactin lactone via intramolecular Reformatsky reaction. | The Journal of organic chemistry 20020208 |
| Fluvastatin enhances apoptosis in cytokine-stimulated vascular smooth muscle cells. | Journal of cardiovascular pharmacology 20020201 |
| Statins and mortality. | European heart journal 20020201 |
| Effects of pravastatin on mortality in patients with and without coronary heart disease across a broad range of cholesterol levels. The Prospective Pravastatin Pooling project. | European heart journal 20020201 |
| Caveolae and cholesterol distribution in vascular smooth muscle cells of different phenotypes. | The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020201 |
| Do lipid-lowering drugs cause erectile dysfunction? A systematic review. | Family practice 20020201 |
| Pharmacokinetic and pharmacodynamic assessments of HMG-CoA reductase inhibitors when coadministered with everolimus. | Journal of clinical pharmacology 20020201 |
| Safety and efficacy of atorvastatin in heart transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020201 |
| Policosanol: clinical pharmacology and therapeutic significance of a new lipid-lowering agent. | American heart journal 20020201 |
| Leptin concentrations in GH deficiency: the effect of GH insensitivity. | The Journal of clinical endocrinology and metabolism 20020201 |
| Modulation of inflammatory mediators and PPARgamma and NFkappaB expression by pravastatin in response to lipoproteins in human monocytes in vitro. | Pharmacological research 20020201 |
| FDA adverse event reports on statin-associated rhabdomyolysis. | The Annals of pharmacotherapy 20020201 |
| Lipid-lowering therapy with fluvastatin inhibits oxidative modification of low density lipoprotein and improves vascular endothelial function in hypercholesterolemic patients. | Atherosclerosis 20020201 |
| The subcellular localization of an unusual rice calmodulin isoform, OsCaM61, depends on its prenylation status. | Plant molecular biology 20020201 |
| Effect of fluvastatin and pravastatin, HMG-CoA reductase inhibitors, on fluconazole activity against Candida albicans. | Journal of medical microbiology 20020201 |
| Detection of coronary microvascular disease by means of cardiac scintigraphy. | The Canadian journal of cardiology 20020201 |
| [Unexpected drug-interaction]. | Rinsho byori. The Japanese journal of clinical pathology 20020201 |
| Effect of pravastatin treatment on the evolution of extracoronary atherosclerosis in renal transplant patients. | Transplantation proceedings 20020201 |
| Pravastatin improves low-density lipoprotein oxidation in renal transplantation. | Transplantation proceedings 20020201 |
| Angiographic intervention trial using HMG CoA reductase inhibitor to evaluate retardation of obstructive multiple atheroma in West Japan (ATHEROMA study): rationale, design and baseline. | Journal of cardiovascular risk 20020201 |
| Atorvastatin versus four statin-fibrate combinations in patients with familial combined hyperlipidaemia. | Journal of cardiovascular risk 20020201 |
| Distinct mechanisms of bisphosphonate action between osteoblasts and breast cancer cells: identity of a potent new bisphosphonate analogue. | Breast cancer research and treatment 20020201 |
| Role of transporters in the tissue-selective distribution and elimination of drugs: transporters in the liver, small intestine, brain and kidney. | Journal of controlled release : official journal of the Controlled Release Society 20020117 |
| Prevention of primary nonfunction of canine islet autografts by treatment with pravastatin. | Transplantation 20020115 |
| Hypercholesterolaemia and lipid lowering treatment do not affect the acute endogenous fibrinolytic capacity in vivo. | Heart (British Cardiac Society) 20020101 |
| Fluorescein uptake by a monocarboxylic acid transporter in human intestinal Caco-2 cells. | Biochemical pharmacology 20020101 |
| Effects of pravastatin treatment on lipoprotein subclass profiles and particle size in the PLAC-I trial. | Atherosclerosis 20020101 |
| Pravastatin suppress superoxide and fibronectin production of glomerular mesangial cells induced by oxidized-LDL and high glucose. | Atherosclerosis 20020101 |
| A pharmacoepidemiological assessment of the effect of statins and fibrates on fibrinogen concentration. | Atherosclerosis 20020101 |
| Effect of pravastatin on responsiveness to N-monomethyl-L-arginine in patients with hypercholesterolaemia. | Atherosclerosis 20020101 |
| Remarkably high prevalence of small dense low-density lipoprotein in Japanese men with coronary artery disease, irrespective of the presence of diabetes. | Atherosclerosis 20020101 |
| Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia. | Expert opinion on investigational drugs 20020101 |
| Rhabdomyolysis and statin therapy: relevance to the elderly. | The American journal of geriatric cardiology 20020101 |
| HMG CoA reductase inhibitors affect the fibrinolytic system of human vascular cells in vitro: a comparative study using different statins. | British journal of pharmacology 20020101 |
| Maintenance of low-density lipoprotein goal with step-down pravastatin therapy. | Pharmacotherapy 20020101 |
| Cholesterol-dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons. | Journal of neurochemistry 20020101 |
| Poststroke emotional incontinence and decreased sexual activity. | Cerebrovascular diseases (Basel, Switzerland) 20020101 |
| Cholesterol, essential fatty acids, and suicide. | Pharmacopsychiatry 20020101 |
| Influence of high cholesterol diet and pravastatin sodium on the initiation of liver regeneration in rats after partial hepatectomy. | Nutrition (Burbank, Los Angeles County, Calif.) 20020101 |
| Effect of early telephone and postal reminders on medication compliance with pravastatin therapy. | Clinical therapeutics 20020101 |
| Effects of pravastatin on superoxide and fibronectin production of mesangial cells induced by low-density lipoprotein. | Kidney & blood pressure research 20020101 |
| Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia. | Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians 20020101 |
| Statins, platelet aggregation and coronary heart disease. | Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians 20020101 |
| Requirement of Rho-family GTPases in the invasion of Type 1-piliated uropathogenic Escherichia coli. | Cellular microbiology 20020101 |
| Effect of simvastatin on bone markers in osteopenic women: a placebo-controlled, dose-ranging trial [ISRCTN85429598]. | BMC musculoskeletal disorders 20020101 |
| The case for early statin therapy in acute coronary syndromes. | Cardiology in review 20020101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020101 |
| Effects of pravastatin on exercise electrocardiography test performance and cardiovascular mortality and morbidity in patients with hypercholesterolemia: Lipid Intervention Study in Kyoto. | Circulation journal : official journal of the Japanese Circulation Society 20020101 |
| Statins as modulators of bone formation. | Arthritis research 20020101 |
| Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. | Clinical pharmacokinetics 20020101 |
| The role of statins as potential targets for bone formation. | Arthritis research 20020101 |
| Statin specific toxicity in organ transplant recipients: case report and review of the literature. | Journal of nephrology 20020101 |
| Interventions in the management of serum lipids for preventing stroke recurrence. | The Cochrane database of systematic reviews 20020101 |
| A 'bad responder' to statins. | Cardiology 20020101 |
| The effects of combination therapy with niceritrol and pravastatin on hyperlipidaemia. | The Journal of international medical research 20020101 |
| Micronised fenofibrate: an updated review of its clinical efficacy in the management of dyslipidaemia. | Drugs 20020101 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020101 |
| Prognosis of hypercholesterolemic patients taking pravastatin for five years: the Chiba Lipid Intervention Program (CLIP) Study. | Journal of atherosclerosis and thrombosis 20020101 |
| [Hypothyroidism, pravastatin therapy and myopathy]. | Duodecim; laaketieteellinen aikakauskirja 20020101 |
| Oxysterol-induced apoptosis of vascular smooth muscle cells is reduced by HMG-CoA reductase inhibitor, pravastatin. | Journal of atherosclerosis and thrombosis 20020101 |
| Oxidation injury in patients receiving HMG-CoA reductase inhibitors: occurrence in patients without enzyme elevation or myopathy. | Drug safety 20020101 |
| Rosuvastatin. | Drugs 20020101 |
| [Concentration on Diapak C 16 capsules of lovastatin, mevinolinic acid and other inhibitors of biosynthesis of sterins produced by Penicillium citrinum 89]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101 |
| Health-related quality of life and long-term therapy with pravastatin and tocopherol (vitamin E) in older adults. | Drugs & aging 20020101 |
| Mevastatin, an inhibitor of HMG-CoA reductase, induces apoptosis, differentiation and Rap1 expression in HL-60 cells. | Physiological chemistry and physics and medical NMR 20020101 |
| Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection. | Clinical pharmacokinetics 20020101 |
| Effect of pravastatin-induced LDL-cholesterol reduction on coronary heart disease and cerebrovascular disease in Japanese: Hokuriku lipid coronary heart disease study-pravastatin atherosclerosis trial (Holicos-PAT). | Journal of atherosclerosis and thrombosis 20020101 |
| Colchicine-induced acute myopathy in a patient with concomitant use of simvastatin. | Clinical neuropharmacology 20020101 |
| Benefits and menaces related to the use of statins in patients after renal transplantation. | Annals of transplantation 20020101 |
| Role of inflammation in cardiovascular disease: how to use C-reactive protein in clinical practice. | Progress in cardiovascular nursing 20020101 |
| Statins and menopause. | Drugs 20020101 |
| A multidisciplinary program for achieving lipid goals in chronic hemodialysis patients. | BMC nephrology 20020101 |
| The anatomy of a clinical trial. The West of Scotland Coronary Prevention Study. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20020101 |
| [Pravastatin: pharmacological action, pleiotropic effects and efficacy in prevention of atherosclerosis]. | Kardiologiia 20020101 |
| [Correction of atherogenic exogenously-induced postprandial hyperlipidemia with pravastatin]. | Kardiologiia 20020101 |
| The discovery and development of atorvastatin, a potent novel hypolipidemic agent. | Progress in medicinal chemistry 20020101 |
| The in vitro inhibitory effects of crude extracts of traditional Chinese herbs on 3-hydroxy-3-methylglutaryl-coenzyme A reductase on Vero cells. | The American journal of Chinese medicine 20020101 |
| Differential effect of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on plasma paraoxonase 1 activity in the rat. | Polish journal of pharmacology 20020101 |
| The eye lens evaluation of the atorvastatin-treated white rat. | Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101 |
| Strategies for minimizing hyperlipidemia after cardiac transplantation. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101 |
| Management of protease inhibitor-associated hyperlipidemia. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101 |
| How do HMG-CoA reductase inhibitors prevent stroke? | American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101 |
| Integrating cost-effectiveness evidence into clinical practice guidelines in Australia for acute myocardial infarction. | The European journal of health economics : HEPAC : health economics in prevention and care 20020101 |
| Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins. | The Journal of biological chemistry 20011214 |
| Estrogen/progesterone replacement versus pravastatin and their sequential association in hypercholesterolemic postmenopausal women. | Maturitas 20011214 |
| Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells. | The Biochemical journal 20011201 |
| Effect of pravastatin on endothelial function in patients with coronary artery disease (cholesterol-independent effect of pravastatin). | The American journal of cardiology 20011201 |
| Participant recruitment in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). | Controlled clinical trials 20011201 |
| The effects of lipid-lowering and antioxidant vitamin therapies on flow-mediated vasodilation of the brachial artery in older adults with hypercholesterolemia. | Journal of the American College of Cardiology 20011201 |
| Pravastatin improves cerebral vasomotor reactivity in patients with subcortical small-vessel disease. | Stroke 20011201 |
| Downregulation of angiotensin II type 1 receptor by hydrophobic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in vascular smooth muscle cells. | Arteriosclerosis, thrombosis, and vascular biology 20011201 |
| Effect of statin therapy on remnant lipoprotein cholesterol levels in patients with combined hyperlipidemia. | Arteriosclerosis, thrombosis, and vascular biology 20011201 |
| Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin. | Clinical pharmacology and therapeutics 20011201 |
| Can the potential benefits of statins in general medical practice be extrapolated to liver transplantation? | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20011201 |
| Alpha tocopheryl succinate, retinoic acid and polar carotenoids enhanced the growth-inhibitory effect of a cholesterol-lowering drug on immortalized and transformed nerve cells in culture. | Journal of the American College of Nutrition 20011201 |
| Cost-effectiveness analysis of applying the Cholesterol and Recurrent Events (CARE) study protocol in Hong Kong. | Hong Kong medical journal = Xianggang yi xue za zhi 20011201 |
| [Lipid-lowering drugs]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20011201 |
| A comparison of continuous combined hormone replacement therapy, HMG-CoA reductase inhibitor and combined treatment for the management of hypercholesterolemia in postmenopausal women. | The journal of obstetrics and gynaecology research 20011201 |
| Stability of atheromatous plaque affected by lesional composition: study of WHHL rabbits treated with statins. | Annals of the New York Academy of Sciences 20011201 |
| The use of fibrates and of statins in preventing atherosclerosis in diabetes. | Current opinion in lipidology 20011201 |
| Antioxidative effects of fluvastatin and its metabolites against oxidative DNA damage in mammalian cultured cells. | Free radical research 20011201 |
| Fluvastatin depresses the enhanced lipid peroxidation in vitamin E-deficient hamsters. | Free radical research 20011201 |
| Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolaemic patients: a randomized, double-blind study. | Journal of cardiovascular risk 20011201 |
| Effect of diet and treatment with statins on platelet-dependent thrombin generation in hypercholesterolemic subjects. | Nutrition, metabolism, and cardiovascular diseases : NMCD 20011201 |
| Low-density-lipoprotein cholesterol goals for patients with coronary disease: treating between the lines. | Circulation 20011127 |
| High-sensitivity C-reactive protein: potential adjunct for global risk assessment in the primary prevention of cardiovascular disease. | Circulation 20011127 |
| Effect of pravastatin on myocardial protection during coronary angioplasty and the role of adenosine. | The American journal of cardiology 20011115 |
| Cholesterol lowering with statins reduces exercise-induced myocardial ischemia in hypercholesterolemic patients with coronary artery disease. | The American journal of cardiology 20011115 |
| Do statins reduce the risk for diabetes by improving exercise capacity? | Circulation 20011113 |
| CNS synaptogenesis promoted by glia-derived cholesterol. | Science (New York, N.Y.) 20011109 |
| Locking a leukocyte integrin with statins. | The New England journal of medicine 20011108 |
| Cost-effectiveness of prescribing statins according to pharmaceutical benefits scheme criteria. | The Medical journal of Australia 20011105 |
| Use of a reporter gene assay to predict and rank the potency and efficacy of CYP3A4 inducers. | Drug metabolism and disposition: the biological fate of chemicals 20011101 |
| Pravastatin and endothelium dependent vasomotion after coronary angioplasty: the PREFACE trial. | Heart (British Cardiac Society) 20011101 |
| Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, attenuates renal injury in an experimental model of ischemia-reperfusion. | The Journal of surgical research 20011101 |
| HMG-CoA reductase inhibitors reduce vascular monocyte chemotactic protein-1 expression in early lesions from hypercholesterolemic swine independently of their effect on plasma cholesterol levels. | Atherosclerosis 20011101 |
| In patients with heart disease, is the benefit of lipid-lowering therapy with statins similar in older patients to that in younger patients? | The Journal of family practice 20011101 |
| Development of indicators for assessing the quality of prescribing of lipid-lowering drugs: data from the pharmacotherapeutic quality circles in Hesse, Germany. | International journal of clinical pharmacology and therapeutics 20011101 |
| Lovastatin increases nitric oxide synthesis in IL-1 beta-stimulated smooth muscle cells. | Chinese medical journal 20011101 |
| The use over time of statins in coronary patients in an Italian tertiary referral center. | Italian heart journal : official journal of the Italian Federation of Cardiology 20011101 |
| Healthy ageing: addressing acute coronary syndrome? | European heart journal 20011101 |
| Effect of hydroxymethylglutaryl coenzyme a reductase inhibitors on the progression of calcific aortic stenosis. | Circulation 20011030 |
| Potency of select statin drugs in a new mouse model of hyperlipidemia and atherosclerosis. | International journal of pharmaceutics 20011023 |
| Alzheimer's disease. Bad for the heart, bad for the mind? | Science (New York, N.Y.) 20011019 |
| [Can the action of statins reveal etiology of coronary diseases?]. | Lakartidningen 20011017 |
| beta-Oxidation of simvastatin in mouse liver preparations. | Drug metabolism and disposition: the biological fate of chemicals 20011001 |
| Hyperlipidaemia and cardiovascular disease. | Current opinion in lipidology 20011001 |
| Effects of low-dose pravastatin on plasma levels of lipids and apolipoproteins in Japanese type II hyperlipoproteinemic subjects with apolipoprotein E phenotype E3/2, E3/3, and E4/3. | Journal of clinical pharmacology 20011001 |
| Clinically relevant differences between the statins: implications for therapeutic selection. | The American journal of medicine 20011001 |
| The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, ezetimibe, in combination with 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors in dogs. | Metabolism: clinical and experimental 20011001 |
| Effect of lipid-lowering therapy with pravastatin on myocardial blood flow in young mildly hypercholesterolemic adults. | Journal of cardiovascular pharmacology 20011001 |
| Effect of statins on bone mineral density and bone histomorphometry in rodents. | Arteriosclerosis, thrombosis, and vascular biology 20011001 |
| [Cholesterol, omega-3 fatty acids, and suicide risk: empirical evidence and pathophysiological hypotheses]. | Fortschritte der Neurologie-Psychiatrie 20011001 |
| Pravastatin suppresses the interleukin-8 production induced by thrombin in human aortic endothelial cells cultured with high glucose by inhibiting the p44/42 mitogen activated protein kinase. | British journal of pharmacology 20011001 |
| Paraoxonase genotype modifies the effect of pravastatin on high-density lipoprotein cholesterol. | Pharmacogenetics 20011001 |
| Simvastatin and atorvastatin enhance hypotensive effect of diltiazem in rats. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20011001 |
| Effects of pravastatin therapy on serum lipids and coronary reactivity are not associated with SREBP cleavage-activating protein polymorphism in healthy young men. | Clinical genetics 20011001 |
| Managed care trends in statin usage. | Managed care (Langhorne, Pa.) 20011001 |
| [Effect of hypolipemic agents on levels of total plasma homocysteine]. | Vnitrni lekarstvi 20011001 |
| Fluvastatin in combination with rad significantly reduces graft vascular disease in rat cardiac allografts. | Transplantation 20010927 |
| Low-density lipoprotein size, pravastatin treatment, and coronary events. | JAMA 20010926 |
| Effect of pravastatin-to-simvastatin conversion on low-density-lipoprotein cholesterol. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010915 |
| [Hypersensitivity pneumonitis in a patient taking pravastatin]. | Revue des maladies respiratoires 20010901 |
| Serum leptin levels in wild and captive populations of baboons (papio): implications for the ancestral role of leptin. | The Journal of clinical endocrinology and metabolism 20010901 |
| Effects of lovastatin and pravastatin on cognitive function in military aircrew. | Aviation, space, and environmental medicine 20010901 |
| Improvement of endothelial function in insulin-resistant carotid arteries treated with pravastatin. | Journal of neurosurgery 20010901 |
| Smoking diminishes the beneficial effect of statins: observations from the landmark trials. | Angiology 20010901 |
| [Cholesterin synthase inhibition and atherosclerosis]. | Der Internist 20010901 |
| Rhabdomyolysis and HMG-CoA reductase inhibitors. | The Annals of pharmacotherapy 20010901 |
| Cerivastatin versus branded pravastatin in the treatment of primary hypercholesterolemia in primary care practice in Canada: a one-year, open-label, randomized, comparative study of efficacy, safety, and cost-effectiveness. | Clinical therapeutics 20010901 |
| Statins in acute coronary syndromes: from bench to bedside. | International journal of clinical practice 20010901 |
| Long-term efficacy and safety of cerivastatin 0.8 mg in patients with primary hypercholesterolemia. | Clinical cardiology 20010901 |
| Role of cardiac ATP-sensitive K+ channels induced by HMG CoA reductase inhibitor in ischemic rabbit hearts. | Hypertension research : official journal of the Japanese Society of Hypertension 20010901 |
| Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner. | Methods and findings in experimental and clinical pharmacology 20010901 |
| Statins in the 21st century: end of the simple story? | Expert opinion on investigational drugs 20010901 |
| Antiinflammatory and antiarteriosclerotic actions of HMG-CoA reductase inhibitors in a rat model of chronic inhibition of nitric oxide synthesis. | Circulation research 20010831 |
| Dietary advice with or without pravastatin for the management of hypercholesterolaemia associated with protease inhibitor therapy. | AIDS (London, England) 20010817 |
| Are we aggressive enough in lowering cholesterol? | The American journal of cardiology 20010816 |
| Achieving and maintaining National Cholesterol Education Program low-density lipoprotein cholesterol goals with five statins. | The American journal of medicine 20010815 |
| The platelet Pl(A2) and angiotensin-converting enzyme (ACE) D allele polymorphisms and the risk of recurrent events after acute myocardial infarction. | The American journal of cardiology 20010815 |
| Inhibitory effects of fluvastain and its metabolites on the formation of several reactive oxygen species. | Life sciences 20010810 |
| Correlation of non-high-density lipoprotein cholesterol with apolipoprotein B: effect of 5 hydroxymethylglutaryl coenzyme A reductase inhibitors on non-high-density lipoprotein cholesterol levels. | The American journal of cardiology 20010801 |
| Reduced levels of TNF alpha in hypercholesterolemic individuals after treatment with pravastatin for 8 weeks. | Atherosclerosis 20010801 |
| Combined treatment with low-dose pravastatin and fish oil in post-renal transplantation dislipidemia. | Nephron 20010801 |
| The effect of pravastatin and atorvastatin on coenzyme Q10. | American heart journal 20010801 |
| Foundations for blockbuster drugs in federally sponsored research. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801 |
| Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins). | British journal of pharmacology 20010801 |
| Possible relationship between statin use and decreased incidence of dementia: are we ready for a new indication for these drugs? | Archives of internal medicine 20010801 |
| A new statin: a new standard. | Clinical cardiology 20010801 |
| Shoulder stiffness: a common adverse effect of HMG-CoA reductase inhibitors in women? | Internal medicine (Tokyo, Japan) 20010801 |
| Possible active transport mechanism in pharmacokinetics of flunixin-meglumin in rabbits. | The Journal of veterinary medical science 20010801 |
| Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitors (statins). | European journal of clinical pharmacology 20010801 |
| Effect of pravastatin in mildly hypercholesterolemic young men on serum matrix metalloproteinases. | The American journal of cardiology 20010715 |
| Effect of cholesterol-lowering therapy on endothelial function. | Circulation 20010710 |
| Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study. | JAMA 20010704 |
| Placing PRINCE in perspective. | JAMA 20010704 |
| HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. | Carcinogenesis 20010701 |
| Is pseudocholinesterase activity related to markers of triacylglycerol synthesis in Type II diabetes mellitus? | Clinical science (London, England : 1979) 20010701 |
| Influence of pravastatin on lipoproteins, and on endothelial, platelet, and inflammatory markers in subjects with peripheral artery disease. | The American journal of cardiology 20010701 |
| Fibromuscular cap composition is important for the stability of established atherosclerotic plaques in mature WHHL rabbits treated with statins. | Atherosclerosis 20010701 |
| Lipophilic statins augment inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes. | Journal of cardiovascular pharmacology 20010701 |
| Statins and dementia. | Archives of neurology 20010701 |
| Long-term risk stratification for survivors of acute coronary syndromes. Results from the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Study. LIPID Study Investigators. | Journal of the American College of Cardiology 20010701 |
| Pravastatin reduces myocardial lesions induced by acute inhibition of nitric oxide biosynthesis in normocholesterolemic rats. | International journal of cardiology 20010701 |
| Effects of fluvastatin and its major metabolites on low-density lipoprotein oxidation and cholesterol esterification in macrophages. | Japanese journal of pharmacology 20010701 |
| Short-term effects of statin therapy in patients with hyperlipoproteinemia after liver transplantation: results of a randomized cross-over trial. | Journal of hepatology 20010701 |
| Heart lines. Can statins help prevent diabetes? | Harvard heart letter : from Harvard Medical School 20010701 |
| The role of cytochrome P450-mediated drug-drug interactions in determining the safety of statins. | Expert opinion on pharmacotherapy 20010701 |
| The in vitro inhibitory effect of flavonoid astilbin on 3-hydroxy-3-methylglutaryl coenzyme A reductase on Vero cells. | Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20010701 |
| Conversion of cyclic nonaketides to lovastatin and compactin by a lovC deficient mutant of Aspergillus terreus. | Bioorganic & medicinal chemistry letters 20010618 |
| Statins and fractures. | Lancet (London, England) 20010609 |
| Compactin enhances osteogenesis in murine embryonic stem cells. | Biochemical and biophysical research communications 20010608 |
| Limitation of heart growth in neonatal piglets by simvastatin and atorvastatin: comparison with pravastatin. | American journal of physiology. Heart and circulatory physiology 20010601 |
| Human liver-specific organic anion transporter, LST-1, mediates uptake of pravastatin by human hepatocytes. | The Journal of pharmacology and experimental therapeutics 20010601 |
| PRINCE's prospects: statins, inflammation, and coronary risk. | American heart journal 20010601 |
| The pravastatin inflammation CRP evaluation (PRINCE): rationale and design. | American heart journal 20010601 |
| Randomized clinical trials and recent patterns in the use of statins. | American heart journal 20010601 |
| Fluvastatin suppresses oxidative stress and fibrosis in the interstitium of mouse kidneys with unilateral ureteral obstruction. | Kidney international 20010601 |
| Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site. | Nature medicine 20010601 |
| Effect of lovastatin, an HMG CoA reductase inhibitor, on acute renal allograft rejection. | Clinical transplantation 20010601 |
| HMG-CoA reductase inhibitors prevent migration of human coronary smooth muscle cells through suppression of increase in oxidative stress. | Arteriosclerosis, thrombosis, and vascular biology 20010601 |
| Simvastatin-associated memory loss. | Pharmacotherapy 20010601 |
| Safety and efficacy of pravastatin therapy for the prevention of hyperlipidemia in pediatric and adolescent cardiac transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20010601 |
| Statin therapy and the prevention of dementia. | Archives of neurology 20010601 |
| Pravastatin therapy increases procollagen I N-terminal propeptide (PINP), a marker of bone formation in post-menopausal women. | Clinica chimica acta; international journal of clinical chemistry 20010601 |
| Inhibition of growth of methane-producing bacteria of the ruminant forestomach by hydroxymethylglutaryl-SCoA reductase inhibitors. | Journal of dairy science 20010601 |
| The effects of postal and telephone reminders on compliance with pravastatin therapy in a national registry: results of the first myocardial infarction risk reduction program. | Clinical therapeutics 20010601 |
| [Stroke, cholesterol and statins--are there new data about stroke prevention?]. | Deutsche medizinische Wochenschrift (1946) 20010601 |
| Diabetes, statins and cardiovascular disease. | International journal of clinical practice 20010601 |
| Pravastatin in acute ischaemic syndromes: results of a randomised placebo-controlled trial. | International journal of clinical practice 20010601 |
| Plasmodium falciparum: the lethal effects of tunicamycin and mevastatin on the parasite are not mediated by the inhibition of N-linked oligosaccharide biosynthesis. | Experimental parasitology 20010601 |
| HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein. | Pharmaceutical research 20010601 |
| [CSE inhibitors after coronary event. How soon administered?]. | MMW Fortschritte der Medizin 20010531 |
| Chromatographic purification of some 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. | Journal of chromatography. A 20010525 |
| Synthesis and biological evaluations of condensed pyridine and condensed pyrimidine-based HMG-CoA reductase inhibitors. | Bioorganic & medicinal chemistry letters 20010521 |
| Benefits of pravastatin on cardiovascular events and mortality in older patients with coronary heart disease are equal to or exceed those seen in younger patients: Results from the LIPID trial. | Annals of internal medicine 20010515 |
| Summaries for patients. Benefits of lowering cholesterol levels in older patients. | Annals of internal medicine 20010515 |
| [Statins as new therapeutic possibility in osteoporosis?]. | Deutsche medizinische Wochenschrift (1946) 20010511 |
| Cholesterol ester accumulation: an immediate consequence of acute in vivo ischemic renal injury. | Kidney international 20010501 |
| Aggressive versus moderate lipid-lowering therapy in postmenopausal women with hypercholesterolemia: Rationale and design of the Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES) trial. | American heart journal 20010501 |
| Cost-effectiveness of pravastatin therapy for survivors of myocardial infarction with average cholesterol levels. | American heart journal 20010501 |
| Effects of 1-year treatment with fluvastatin or pravastatin on bone. | The American journal of medicine 20010501 |
| Interactions of leptin and thyrotropin 24-hour secretory profiles in short normal children. | The Journal of clinical endocrinology and metabolism 20010501 |
| The in vitro inhibitory effect of tannin derivatives on 3-hydroxy-3-methylglutaryl-coenzyme a reductase on vero cells. | Pharmacology 20010501 |
| What do the statin trials tell us? | The American journal of managed care 20010501 |
| [Pravastatin and the development of diabetes mellitus. Evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010501 |
| Statin induced myopathy does not show up in MIBI scintigraphy. | Nuclear medicine communications 20010501 |
| Protective effects of Saiko-ka-ryukotsu-borei-to (Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) against atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. | Pharmacological research 20010501 |
| A cost-effectiveness model of alternative statins to achieve target LDL-cholesterol levels. | International journal of clinical practice 20010501 |
| Reassuring effect of pravastatin on natural killer cell activity in stable renal transplant patients. | Transplantation 20010427 |
| New pharmacologic aspects of CS-866, the newest angiotensin II receptor antagonist. | The American journal of cardiology 20010419 |
| [Acute coronary syndrome. Early lipid reduction decreases risk of recurrence]. | MMW Fortschritte der Medizin 20010419 |
| Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels. | Circulation 20010417 |
| Assessing the results: phase 1 hyperlipidemia outcomes in 27 health plans. | The American journal of medicine 20010416 |
| [Effect on plasma fibrinogen of hypercholesterolaemia treatment with pravastatin]. | Atencion primaria 20010415 |
| Safety of statins (hydroxymethyl glutaryl coenzyme a reductase inhibitors): different mechanisms of metabolism and drug transport may have clinical relevance. | Archives of internal medicine 20010409 |
| Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts. | Journal of cellular physiology 20010401 |
| Comparative study of HMG-CoA reductase inhibitors on fibrinogen. | Atherosclerosis 20010401 |
| Recent clinical trial highlights in hypertension. | Current hypertension reports 20010401 |
| A new simvastatin (mevinolin)-resistance marker from Haloarcula hispanica and a new Haloferax volcanii strain cured of plasmid pHV2. | Microbiology (Reading, England) 20010401 |
| Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice. | Stroke 20010401 |
| Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial. | British journal of cancer 20010401 |
| Therapeutic change of HMG-CoA reductase inhibitors in patients with coronary artery disease. | Pharmacotherapy 20010401 |
| Baseline characteristics of the diabetic participants in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). | Diabetes care 20010401 |
| Pravastatin attenuates lower torso ischaemia-reperfusion-induced lung injury by upregulating constitutive endothelial nitric oxide synthase. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20010401 |
| [Secondary prevention of coronary artery disease with lipid-lowering drugs]. | Annales de medecine interne 20010401 |
| [Does statin therapy reduce the risk of stroke? A meta-analysis]. | Annales de medecine interne 20010401 |
| Statins enhance arachidonic acid synthesis in hypercholesterolemic patients. | Nutrition, metabolism, and cardiovascular diseases : NMCD 20010401 |
| The relationship between low-density lipoprotein cholesterol goal attainment and prevention of coronary heart disease--related events. | Journal of cardiovascular pharmacology and therapeutics 20010401 |
| The effect of HMG-CoA reductase inhibitors on chronic allograft rejection. | Expert opinion on emerging drugs 20010401 |
| Pravastatin and coronary heart disease. | Lancet (London, England) 20010331 |
| Dementia and statins. PROSPER study group. | Lancet (London, England) 20010317 |
| Dementia and statins. | Lancet (London, England) 20010317 |
| 3-Hydroxy-3-methylglutaryl coenzyme A synthase-1 of Blattella germanica has structural and functional features of an active retrogene. | Insect biochemistry and molecular biology 20010315 |
| Effect of pravastatin on plasma markers of inflammation and peripheral endothelial function in male heart transplant recipients. | The American journal of cardiology 20010315 |
| Statin therapy: where are we? Where do we go next? | The American journal of cardiology 20010308 |
| Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. | The American journal of cardiology 20010308 |
| A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro. | Drug metabolism and disposition: the biological fate of chemicals 20010301 |
| Design and rationale of the ARBITER trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol)--a randomized trial comparing the effects of atorvastatin and pravastatin on carotid artery intima-media thickness. | American heart journal 20010301 |
| HMG-CoA reductase inhibitors and P-glycoprotein modulation. | British journal of pharmacology 20010301 |
| Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228. | International journal of cancer 20010301 |
| Statin therapy--what now? | Drug and therapeutics bulletin 20010301 |
| Statin-fibrate combinations in patients with combined hyperlipedemia. | Atherosclerosis 20010301 |
| Medical-economical aspects of high sensitivity C-reactive protein assay for the prediction of coronary heart disease. An analysis in Germany and Italy. | Italian heart journal : official journal of the Italian Federation of Cardiology 20010301 |
| [Treatment with statins for the reduction of cardiovascular risk]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010301 |
| [Effects of pravastatin in 3260 patients with unstable angina: results from the LIPID study]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010301 |
| Role of fibrates and HMG-CoA reductase inhibitors in gallstone formation: epidemiological study in an unselected population. | Digestive diseases and sciences 20010301 |
| Is a statin a statin? | International journal of clinical practice 20010301 |
| [WOSCOPS [West of Scotland Coronary Prevention Study]]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| [LIPID study [Long-term Intervention with Pravastatin in Ischaemic Disease study]]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| [REGRESS [The Regression Growth Evaluation Statin Study]]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| [CARE[ Cholesterol and Recurrent Events Trial]]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| [PATE Study [Pravastatin anti-Atherosclerosis Trial in the Elderly Study]]. | Nihon rinsho. Japanese journal of clinical medicine 20010301 |
| Statins: new drugs for treating osteoporosis? | Expert opinion on investigational drugs 20010301 |
| A clinical focus on statins. | Current opinion in investigational drugs (London, England : 2000) 20010301 |
| Suppression of recurrent transient ischemic attacks by a statin agent. | Neurology 20010227 |
| Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. | Circulation 20010220 |
| Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits. | Circulation 20010220 |
| Effect of pravastatin on frequency of fracture in the LIPID study: secondary analysis of a randomised controlled trial. Long-term Intervention with Pravastatin in Ischaemic Disease. | Lancet (London, England) 20010217 |
| [Acute coronary syndrome. Statins in the early phase save lives]. | MMW Fortschritte der Medizin 20010208 |
| Operational aspects of terminating the doxazosin arm of The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). | Controlled clinical trials 20010201 |
| Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition. | Molecular and cellular neurosciences 20010201 |
| Do HMG-CoA reductase inhibitors affect fibrinogen? | The Annals of pharmacotherapy 20010201 |
| Protective effect of fluvastatin on degradation of apolipoprotein B by a radical reaction in human plasma. | Biological & pharmaceutical bulletin 20010201 |
| [Statins: intervention studies, facts and perspectives]. | Annales d'endocrinologie 20010201 |
| Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes. | The Journal of pharmacy and pharmacology 20010201 |
| Clinical relevance of statins: instituting treatment early in acute coronary syndrome patients. | Atherosclerosis. Supplements 20010201 |
| Clinical relevance of statins: their role in secondary prevention. | Atherosclerosis. Supplements 20010201 |
| [Determination of pravastatin in rat liver by RP-HPLC]. | Yao xue xue bao = Acta pharmaceutica Sinica 20010201 |
| Beneficial effects of pravastatin in peri- and postmenopausal hyperlipidemic women: a 5-year study on serum lipid and sex hormone levels. | Maturitas 20010131 |
| Interim monitoring of clinical trials based on long-term binary endpoints. | Statistics in medicine 20010130 |
| Do interventions to reduce coronary heart disease reduce the incidence of type 2 diabetes? A possible role for inflammatory factors. | Circulation 20010123 |
| Statins for stroke: the second story? | Circulation 20010123 |
| Pravastatin and the development of diabetes mellitus: evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study. | Circulation 20010123 |
| Reduction of stroke events with pravastatin: the Prospective Pravastatin Pooling (PPP) Project. | Circulation 20010123 |
| Use of the statins in patients after acute myocardial infarction: does evidence change practice? | Archives of internal medicine 20010122 |
| [Metabolic interactions with statins]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20010120 |
| Effective use of statins to prevent coronary heart disease. | American family physician 20010115 |
| Statin trials in progress: unanswered questions. | Current atherosclerosis reports 20010101 |
| New statins and new doses of older statins. | Current atherosclerosis reports 20010101 |
| Effects of initial and long-term lipid-lowering therapy on vascular wall characteristics. | Atherosclerosis 20010101 |
| Inflammation and coronary heart disease: an overview. | Cardiology in review 20010101 |
| [Antioxidative effects of fluvastatin, and its major metabolites [II]]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010101 |
| Systolic and pulse blood pressures (but not diastolic blood pressure and serum cholesterol) are associated with alterations in carotid intima-media thickness in the moderately hypercholesterolaemic hypertensive patients of the Plaque Hypertension Lipid Lowering Italian Study. PHYLLIS study group. | Journal of hypertension 20010101 |
| Similar effects of atorvastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia. | Thrombosis and haemostasis 20010101 |
| Cholesterol-dependent modulation of tau phosphorylation in cultured neurons. | Journal of neurochemistry 20010101 |
| Hypolipidemic effect of NK-104 and other 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in guinea pigs. | Arzneimittel-Forschung 20010101 |
| Protective effects of fluvastatin against reactive oxygen species induced DNA damage and mutagenesis. | Free radical research 20010101 |
| Advantages of lipid-lowering therapy in cerebral ischemia: role of HMG-CoA reductase inhibitors. | Cerebrovascular diseases (Basel, Switzerland) 20010101 |
| Cost effectiveness of HMG-CoA reductase inhibition in Canada. | The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20010101 |
| New OTC drugs and devices 2000: a selective review. | Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 20010101 |
| Stimulation of inflammatory responses in vitro and in vivo by lipophilic HMG-CoA reductase inhibitors. | International immunopharmacology 20010101 |
| The devil is in the details. | The American journal of geriatric cardiology 20010101 |
| Statin-stimulated nitric oxide release from endothelium. | Medical science monitor : international medical journal of experimental and clinical research 20010101 |
| Elevated baseline triglyceride levels modulate effects of HMGCoA reductase inhibitors on plasma lipoproteins. | Journal of cardiovascular pharmacology and therapeutics 20010101 |
| The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study. | BMC medical research methodology 20010101 |
| [Rhabdomyolysis and acute renal failure secondary to statins]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101 |
| Transplanted livers and kidneys for HIV+ people. | TreatmentUpdate 20010101 |
| Statins for the reduction of risk of Alzheimer's disease. | The Cochrane database of systematic reviews 20010101 |
| Statins for the prevention of Alzheimer's disease. | The Cochrane database of systematic reviews 20010101 |
| Atorvastatin: an updated review of its pharmacological properties and use in dyslipidaemia. | Drugs 20010101 |
| Prolongation of islet allograft survival in mice by combined treatment with pravastatin and low-dose cyclosporine. | Cell transplantation 20010101 |
| Pharmacological intervention in renal fibrosis and vascular sclerosis. | Journal of nephrology 20010101 |
| New data affirm the long-term safety of prevastatin. | Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20010101 |
| [Microbiological research for the Hungarian pharmaceutical industry]. | Acta pharmaceutica Hungarica 20010101 |
| A comparison of low versus standard dose pravastatin therapy for the prevention of cardiovascular events in the elderly: the pravastatin anti-atherosclerosis trial in the elderly (PATE). | Journal of atherosclerosis and thrombosis 20010101 |
| What does the future hold for diabetic dyslipidaemia? | Acta diabetologica 20010101 |
| Efficacy of n-3 polyunsaturated fatty acids after myocardial infarction: results of GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico. | Lipids 20010101 |
| Some nutritional factors influencing mevinolin production by Aspergillus terreus strain. | Folia microbiologica 20010101 |
| Atorvastatin plus pravastatin for the treatment of heterozygous familial hypercholesterolaemia--a pilot study. | Current medical research and opinion 20010101 |
| If LDL-C is the answer...what was the question? What do the data really show? | Heart disease (Hagerstown, Md.) 20010101 |
| Lovastatin inhibits phenylephrine-induced ERK activation and growth of cardiac. | Cardiovascular toxicology 20010101 |
| Differences in the effects of HMG-CoA reductase inhibitors on proliferation and viability of smooth muscle cells in culture. | Atherosclerosis 20000601 |
| Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells. | Biochemical and biophysical research communications 20000519 |
| Pravastatin compared to bezafibrate in the treatment of dyslipidemia in insulin-treated patients with type 2 diabetes mellitus. | Diabetes/metabolism research and reviews 20000101 |
| ras p21 Isoprenylation inhibition induces flat colon tumors in Wistar rats. | Diseases of the colon and rectum 20000101 |
| Rhabdomyolysis and acute renal failure after changing statin-fibrate combinations. | Cardiology 20000101 |
| Acute cholestatic hepatitis associated with pravastatin. | The American journal of gastroenterology 19990501 |
| Two different types of exercise-induced muscle pain without myopathy and CK-elevation during HMG-Co-enzyme-A-reductase inhibitor treatment. | Atherosclerosis 19990401 |
| Polymyalgia, hypersensitivity pneumonitis and other reactions in patients receiving HMG-CoA reductase inhibitors: a report of ten cases. | Chest 19990301 |
| Myotonia associated with sarcoidosis: marked exacerbation with pravastatin. | Clinical neuropharmacology 19990101 |
| Porphyria cutanea tarda induced by the use of pravastatin. | Archives of dermatology 19981001 |
| [Influence of pravastatin therapy on expression of P-selectin]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 19980901 |
| Peripheral neuropathy and lipid-lowering therapy. | Southern medical journal 19980701 |
| Purification and characterization of two mevalonate pyrophosphate decarboxylases from rat liver: a novel molecular species of 37 kDa. | Journal of biochemistry 19970901 |
| Effects of HMG-CoA reductase inhibitors on growth and differentiation of cultured rat skeletal muscle cells. | Biochimica et biophysica acta 19960412 |
| [Reduction of cardiovascular events with pravastatin. A pooled analysis of clinical events within the scope of the Pravastatin Atherosclerosis Intervention Program]. | Fortschritte der Medizin 19960320 |
| Reduction in cardiovascular events during pravastatin therapy. Pooled analysis of clinical events of the Pravastatin Atherosclerosis Intervention Program. | Circulation 19951101 |
| (Aryloxy)methylsilane derivatives as new cholesterol biosynthesis inhibitors: synthesis and hypocholesterolemic activity of a new class of squalene epoxidase inhibitors. | Journal of medicinal chemistry 19950818 |
| Pravastatin-associated myopathy. Report of a case. | Recenti progressi in medicina 19950501 |
| HMG-CoA reductase inhibitor therapy and peripheral neuropathy. | Annals of internal medicine 19940601 |
| [Porphyria cutanea tarda induced by HMG CoA reductase inhibitors: simvastatin, pravastatin]. | Annales de dermatologie et de venereologie 19940101 |
| Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors. | Journal of medicinal chemistry 19931112 |
| Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors. | Journal of medicinal chemistry 19931112 |
| Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase. | Biochemical pharmacology 19930609 |
| RG 12561 (dalvastatin): a novel synthetic inhibitor of HMG-CoA reductase and cholesterol-lowering agent. | Pharmacology 19930101 |
| Depressive symptoms in hypercholesterolaemic patients treated with pravastatin. | Lancet (London, England) 19921010 |
| Synthesis and biological evaluation of dihydroeptastatin, a novel inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase. | Journal of medicinal chemistry 19920904 |
| Pravastatin-associated inflammatory myopathy. | The New England journal of medicine 19920827 |
| Myopathy associated with HMG-CoA reductase inhibitors (HMGRIs) and cyclosporin A: evaluation in a rat model. | European heart journal 19920701 |
| Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5-disubstituted- pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones. | Journal of medicinal chemistry 19920529 |
| Hepatotoxicity of hydroxy-methyl-glutaryl-coenzyme A reductase inhibitors. | Minerva gastroenterologica e dietologica 19920101 |
| Lack of hypotension with lovastatin and pravastatin. | Lancet (London, England) 19911123 |
| HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies. | The Journal of pharmacology and experimental therapeutics 19910601 |
| Purification and regulation of mevalonate kinase from rat liver. | The Journal of biological chemistry 19900205 |
| Treatment of heterozygous familial hypercholesterolemia with lipid-lowering drugs. | Arteriosclerosis (Dallas, Tex.) 19890101 |